Product Image

Sports Energy Extreme

NOW Sports
4.6
★ ★ ★ ★ ★
(2059 ratings)
Iodine 150 mcg
Vitamin B12 1000 mcg
Chromium 200 mcg
Caffeine 100 mg
Thiamin 10 mg
Vitamin B5 20 mg
Tyrosine 250 mg
Product Image
Score73
A disclosed caffeine dose, tyrosine, and energy cofactors directly support acute alertness. A moderate disclosed caffeine amount and B vitamins provide the clearest energy support, while many amino acids, adaptogens, and performance ingredients are too lightly dosed for focused effects.
How scoring works
Quantity:90 Capsule(s) • (45 servings)
Goals:
Mental Focus
Metabolism Boost
Productivity Boost
Energy
Weight Loss
Cognitive Support
Brain Health
Fitness

Score 73

A disclosed caffeine dose, tyrosine, and energy cofactors directly support acute alertness. A moderate disclosed caffeine amount and B vitamins provide the clearest energy support, while many amino acids, adaptogens, and performance ingredients are too lightly dosed for focused effects.
How scoring works
$12.85($0.28 per serving)
Daily Vita
$ 17.40
iHerb
$ 18.36
Pure Formulas
$ 15.62
Vitacost
$ 18.36
Vitacost
$ 18.36
Amazon
$ 12.85
Report prices

Analysis

A disclosed caffeine dose, tyrosine, and energy cofactors directly support acute alertness. Caffeine supplies the clearest and best-supported contribution.

A moderate disclosed caffeine amount and B vitamins provide the clearest energy support, while many amino acids, adaptogens, and performance ingredients are too lightly dosed for focused effects. Guarana, green tea, and yerba mate may add unquantified caffeine, making total stimulant exposure less predictable for sensitive users.

Methylcobalamin, folate, B6, and iodine provide limited support for cell division and thyroid-related hair maintenance. Their role is mainly corrective when nutrient status is low.

Who is it for
  • Adults seeking Mental Focus support
  • People comfortable with a multi-ingredient capsule formula
  • Users who can review the ingredient list against medicines and existing supplements
Best for
  • Mental Focus
  • Metabolism Boost
  • Productivity Boost

Pros

  • A disclosed caffeine dose, tyrosine, and energy cofactors directly support acute alertness
  • Strongest formulation fit is Mental Focus
  • Main label amounts are disclosed for Thiamine, Riboflavin, Niacin
  • Includes a meaningful Iodine component

Cons

  • too lightly dosed for focused effects
  • Weak fit for Hair Health
  • Several secondary ingredients add breadth without equally strong dose or form support
  • Long ingredient list makes the combined effects and trade-offs harder to predict

Warnings

  • Taurine and rhodiola are modestly dosed, magnesium is minimal, and stacked caffeine sources can disrupt sleep or cause jitteriness in sensitive users.
  • Total caffeine exceeds the stated caffeine powder because several plant sources may contribute more, increasing the risk of jitters, sleep disruption, or a rapid heart rate.

Nutrient quality

64 Moderate impact

Caffeine and several useful nutrient forms directly support energy and alertness. Unknown added caffeine and many lightly dosed actives reduce balance and depth.

.

Ingredient transparency

79 High impact

Most active ingredients and their amounts are clearly listed. Daily directions, a complete excipient panel, and some form details are missing from the supplied data.

.

Customer satisfaction

66 High impact

The aggregate rating is favorable and supported by solid feedback volume. Complaint-level experiences are unavailable, so repeated drawbacks and purpose fit remain uncertain.

.

Value for money

80 High impact

Meaningful core ingredients and a low serving cost provide good practical value. Secondary formula limitations do not outweigh the strong economy.

.
Report analysis

Goals

Mental Focus
Mental Focus
Impact
High effect
A- Goal FitC+ Strength of SupportB+ CoverageC+ Formula Quality
Folate · 667 mcg DFEVitamin B6 · 10 mgVitamin B12 · 1000 mcgMagnesium · 15 mgCaffeine · 100 mg

A disclosed caffeine dose, tyrosine, and energy cofactors directly support acute alertness. Caffeine supplies the clearest and best-supported contribution.

Additional caffeine from guarana, green tea, and yerba mate is not quantified, which weakens dose control. The combined stimulant exposure may cause restlessness or sleep disruption, especially when used late in the day.

Study evidence
Caffeine Supportive 128 studies
Metabolism Boost
Metabolism Boost
Impact
High effect
B+ Goal FitC+ Strength of SupportB CoverageB- Formula Quality
Niacin · 20 mgVitamin B12 · 1000 mcgRiboflavin · 10 mgThiamin · 10 mgVitamin B5 · 20 mgVitamin B6 · 10 mgMagnesium · 15 mgCoenzyme Q-10 · 30 mgGreen Tea · 50 mgCaffeine · 100 mg

Caffeine, chromium, iodine, carnitine, and CoQ10 address several metabolic pathways. The stimulant amount is useful, while green tea, carnitine, and CoQ10 are modest for focused support.

B vitamins complement the energy-focused actives and make the formula logically constructed. Several caffeine-containing botanicals leave total stimulant exposure less clear and may trouble sensitive users.

Study evidence
Caffeine Disputed 40 studies
Chromium Supportive 47 studies
Coenzyme Q-10 Disputed 11 studies
Green Tea Supportive 31 studies
Iodine Mixed 17 studies
Magnesium Supportive 61 studies
Productivity Boost
Productivity Boost
Impact
High effect
B+ Goal FitC+ Strength of SupportB CoverageC+ Formula Quality
Vitamin B12 · 1000 mcgVitamin B12 · 1000 mcgVitamin B6 · 10 mgMagnesium · 15 mgEleuthero · 50 mgEleuthero · 50 mgCaffeine · 100 mg

Caffeine, tyrosine, taurine, carnitine, rhodiola, eleuthero, ginseng, and B vitamins create a clear energy-and-productivity formula. The caffeine amount is practical, but tyrosine and the adaptogens are well below common full study doses.

Multiple stimulant plants may add caffeine beyond the stated powder amount, which makes total exposure less predictable. The stack should support short-term alertness more reliably than sustained stress resilience, and stimulant-sensitive users may experience restlessness or sleep disruption.

Study evidence
Caffeine Supportive 108 studies
Eleuthero No effect 1 study
Eleuthero Not classified

No linked studies yet.

Rhodiola Supportive 7 studies
Energy
Energy
Impact
High effect
A- Goal FitC Strength of SupportB CoverageD Formula Quality
Iodine · 150 mcgVitamin B5 · 20 mgMagnesium · 15 mgRiboflavin · 10 mgThiamin · 10 mgVitamin B12 · 1000 mcgCoenzyme Q-10 · 30 mgCaffeine · 100 mg

A clearly listed 100 mg caffeine dose and 1,000 mcg of methylcobalamin provide direct alertness and metabolic support. B vitamins, tyrosine, carnitine, taurine, and adaptogens broaden the formula across several energy pathways.

Guarana, green tea, and yerba mate may add unknown caffeine beyond the stated amount. Rhodiola, eleuthero, citrulline, CoQ10, and several amino acids are too lightly dosed, making the long formula much broader than it is deep.

Study evidence
Caffeine Supportive 68 studies
Citrulline No effect 14 studies
Coenzyme Q-10 Supportive 32 studies
Eleuthero Disputed 3 studies
Guarana No effect 8 studies
Magnesium Supportive 4 studies
Rhodiola Supportive 18 studies
Vitamin B12 Disputed 14 studies
Weight Loss
Weight Loss
Impact
High effect
B+ Goal FitC+ Strength of SupportC+ CoverageD Formula Quality
Iodine · 150 mcgMagnesium · 15 mgGreen Tea · 50 mgCaffeine · 100 mg

Disclosed caffeine provides a direct thermogenic and training-energy effect, with guarana, green tea, and yerba mate likely adding further stimulation. Chromium and iodine support metabolic context, while tyrosine and taurine may help training focus but do not preserve muscle like protein or creatine.

The formula covers several pathways, yet most botanicals and performance ingredients are below focused amounts. Total caffeine exceeds the stated caffeine powder because several plant sources may contribute more, increasing the risk of jitters, sleep disruption, or a rapid heart rate.

Study evidence
Caffeine Disputed 14 studies
Chromium No effect 24 studies
Green Tea Supportive 42 studies
Iodine Adverse 3 studies
Cognitive Support
Cognitive Support
Impact
High effect
B Goal FitC Strength of SupportC+ CoverageC+ Formula Quality
Thiamin · 10 mgVitamin B6 · 10 mgFolate · 667 mcg DFEVitamin B12 · 1000 mcgMagnesium · 15 mgGreen Tea · 50 mg

The sports energy formula is strongly aligned with alertness and mental-drive support. Caffeine, tyrosine, taurine, carnitine, rhodiola, B vitamins, and coenzyme Q10 span stimulation, neurotransmitter precursors, stress, and energy metabolism.

Caffeine is meaningfully dosed, but most supporting actives are below common targeted amounts. The stack is coherent for short-term energy but less convincing for memory or broad cognitive improvement.

Study evidence
Rhodiola Supportive 7 studies

Ingredients

IngredientAmount per serving
Thiamine (Thiamine Hydrochloride, Vitamin B1)
 10 mg
Riboflavin (Vitamin B2)
 10 mg
Niacin (Niacinamide, Vitamin B3)
 20 mg
Vitamin B6 (Pyridoxine Hydrochloride)
 10 mg
Folate
667 mcg DFE
Vitamin B12 (Methylcobalamin)
 1000 mcg
Pantothenic Acid (Calcium Pantothenate)
 20 mg
Iodine (Potassium Iodide)
 150 mcg
Magnesium (Magnesium Malate)
 15 mg
Chromium (Chromium Nicotinate Glycinate)
 200 mcg
natural Caffeine powder
100 mg
Guarana extract
80 mg
Green Tea extract
50 mg
Yerba Mate extract
50 mg
Rhodiola extract
50 mg
organic Eleuthero
50 mg
Panax ginseng
50 mg
Taurine
250 mg
L-Tyrosine
250 mg
L-Carnitine
250 mg
L-Citrulline
100 mg
CoQ10
30 mg
Gluten Free Adults 18–50 Kosher Dairy Free
Report overview
Iodine (Potassium Iodide) · 150 mcg OverallScore96
A+ Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyB+ Value

150 mcg falls within the preferred range for daily iodine support. Potassium iodide is a stable, water-soluble, and readily absorbed iodine form. The serving cost offers good value for an effective iodine dose.

View ingredientView products
Vitamin B12 (Methylcobalamin) · 1000 mcg OverallScore85
A- Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyD+ Value

Bioactive methylcobalamin is clearly disclosed at a level intended for higher needs. The swallowed capsule format relies on normal digestive absorption rather than mucosal delivery. Cost efficiency is moderate after accounting for the bioactive form.

View ingredientView products
Chromium (Chromium Nicotinate Glycinate) · 200 mcg OverallScore77
B- Active Ingredient Quality & BioavailabilityA- Dose, Safety & Label TransparencyB Value

Chromium nicotinate glycinate is an organic, well-absorbed form, but the label gives no branded source. The 200 mcg amount meets the target range, but a single listed weight leaves elemental content ambiguous and dose-adjusted value is favorable. Chromium may lower blood sugar, so people using insulin or sulfonylureas should monitor for hypoglycemia with their prescriber.

View ingredientView products
Loading alternative details
74 Performance

Emotional Balance Support

Thorne
<p>Active B6, methylcobalamin, tyrosine, eleuthero, and rhodiola provide a gentler energy and stress-support pattern without the original’s uncertain multi-source caffeine load. It is not a sports-performance formula, and 5-HTP can interact with serotonin-raising medicines.</p>
68 Budget

Energy Boost Delayed-Release

Swanson
<p>Kola nut, guarana, green tea, ginseng, and eleuthero preserve stimulant-led energy support at slightly lower recurring cost. Multiple caffeine sources make total exposure unclear, and the formula loses the original’s tyrosine, carnitine, taurine, chromium, and CoQ10.</p>
73 Budget

Diet Support

NOW
<p>Green tea EGCG, chromium, iodine, forskolin, and carnitine maintain metabolism and weight-management relevance at slightly lower cost. The formula avoids the original’s stacked caffeine sources, but uva ursi is a poor choice for prolonged use and carnitine remains modest.</p>
68 Value

Triple Action Thyroid

Life Extension
<p>Methylcobalamin, tyrosine, branded ashwagandha, and fermented ginseng provide substantial energy and stress-support ingredients without stacked stimulants. The serving costs more, while repeated iodine and ashwagandha entries plus thyroid-related interaction concerns weaken practical value.</p>
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Patients' experiences with methylcobalamin injections in amyotrophic lateral sclerosis.
    Zubair AS; Saab L; Scharer K; Khokhar B · Brain circulation · 2024
    Qualitative study5 participantsEnergy forVitamin B12
  2. Association between serum vitamin B12 level and frailty in older adults.
    Dokuzlar O; Soysal P; Isik AT · Northern clinics of Istanbul · 2022
    Cross-sectional study335 participantsEnergy forVitamin B12
  3. Physicochemical properties of and volatile compounds in riboflavin fortified cloudy apple juice; study of its effect on job fatigue among Egyptian construction workers.
    Fouad S; Ibrahim GE; Hussein AMS; Ibrahim FA; El Gendy A · Heliyon · 2021
    Non-randomized trialEnergy forRiboflavin
  4. Vitamin B status in patients with chronic fatigue syndrome.
    Heap LC; Peters TJ; Wessely S · Journal of the Royal Society of Medicine · 1999
    Case-control study30 participantsEnergy forRiboflavin
  5. Evidence-based efficacy of adaptogens in fatigue, and molecular mechanisms related to their stress-protective activity.
    Panossian A; Wikman G · Current clinical pharmacology · 2009
    Narrative reviewEnergy forEleuthero Cognitive Support forRhodiola
  6. Randomized controlled trial of Siberian ginseng for chronic fatigue.
    Hartz AJ; Bentler S; Noyes R; Hoehns J; Logemann C; Sinift S; Butani Y; Wang W; Brake K; Ernst M; Kautzman H · Psychological medicine · 2004
    Randomized trial96 participantsEnergy forEleuthero
  7. Dietary supplements and fatigue in patients with breast cancer: a systematic review.
    Pereira PTVT; Reis AD; Diniz RR; Lima FA; Leite RD; da Silva MCP; Guerra RNM; de Moraes Vieira ÉB; Garcia JBS · Breast cancer research and treatment · 2019
    Systematic review932 participants8 studies pooledEnergy forGuarana
  8. Effects of Acute Guarana (Paullinia cupana) Ingestion on Mental Performance and Vagal Modulation Compared to a Low Dose of Caffeine.
    Talik TN; Penna EM; Hack BP; Harp A; Millard-Stafford M · Nutrients · 2024
    Randomized trial20 participantsEnergy forGuarana
  9. Differential cognitive effects of energy drink ingredients: caffeine, taurine, and glucose.
    Giles GE; Mahoney CR; Brunyé TT; Gardony AL; Taylor HA; Kanarek RB · Pharmacology, biochemistry, and behavior · 2013
    Randomized trial48 participantsEnergy forCaffeine
  10. No effects of caffeine on cycling to exhaustion and perceptual responses in non-caffeine-restricted subjects.
    Weippert M; Behrens M; Schlegel M; Schröder T; Tillmann M; Rühe N; Römer R; Mau-Möller A; Bruhn S · Journal of the International Society of Sports Nutrition · 2025
    Randomized trial56 participantsEnergy forCaffeine
  11. A critical review of caffeine withdrawal: empirical validation of symptoms and signs, incidence, severity, and associated features.
    Juliano LM; Griffiths RR · Psychopharmacology · 2005
    Systematic review66 studies pooledEnergy forCaffeine
  12. Effects of modafinil and caffeine on night-time vigilance of air force crewmembers: A randomized controlled trial.
    Wingelaar-Jagt YQ; Bottenheft C; Riedel WJ; Ramaekers JG · Journal of psychopharmacology (Oxford, England) · 2023
    Randomized trial32 participantsMental Focus forCaffeine
  13. Acute effects of caffeine on attention: a comparison of non-consumers and withdrawn consumers.
    Smith AP; Christopher G; Sutherland D · Journal of psychopharmacology (Oxford, England) · 2013
    Randomized trial70 participantsMental Focus forCaffeine
  14. Caffeinated Coffee and Tea Consumption, Genetic Variation and Cognitive Function in the UK Biobank.
    Cornelis MC; Weintraub S; Morris MC · The Journal of nutrition · 2020
    Cross-sectional study445,786 participantsMental Focus forCaffeine
  15. Quantitative Analysis of Selected Circulating Hematological Biomarkers, Essential Minerals, Vitamins, and Thyroid Hormones in Females Affected by Hair Loss.
    Al-Fawaeir S; Al-Odat I · Diseases (Basel, Switzerland) · 2025
    Case-control study200 participantsHair Health forVitamin B12
  16. A comprehensive investigation of biochemical status in patients with telogen effluvium: Analysis of Hb, ferritin, vitamin B12, vitamin D, thyroid function tests, zinc, copper, biotin, and selenium levels.
    Durusu Turkoglu IN; Turkoglu AK; Soylu S; Gencer G; Duman R · Journal of cosmetic dermatology · 2024
    Case-control study180 participantsHair Health forVitamin B12
  17. Hair Loss After Laparoscopic Sleeve Gastrectomy.
    Katsogridaki G; Tzovaras G; Sioka E; Perivoliotis K; Zachari E; Magouliotis D; Tasiopoulou V; Chatedaki C; Zacharoulis D · Obesity surgery · 2019
    Cohort study50 participantsHair Health forVitamin B12
  18. [Evaluation of the role of dietary intake in the occurrence of alopecia].
    El Fékih N; Kamoun H; Fazaa B; El Ati J; Zouari B; Kamoun MR; Gaigi S · Revue medicale de Liege · 2010
    Case-control study272 participantsHair Health forIodine
  19. Comparison of nutritional supplements in improving glycolipid metabolism and endocrine function in polycystic ovary syndrome: a systematic review and network meta-analysis.
    Hu X; Wang W; Su X; Peng H; Tan Z; Li Y; Huang Y · PeerJ · 2023
    Meta-analysis2,362 participants41 studies pooledMetabolism Boost forChromium Metabolism Boost forCoenzyme Q-10
  20. Improved meta-analytic methods show no effect of chromium supplements on fasting glucose.
    Bailey CH · Biological trace element research · 2014
    Meta-analysis809 participants16 studies pooledMetabolism Boost forChromium
  21. Chromium supplementation in non-obese non-diabetic subjects is associated with a decline in insulin sensitivity.
    Masharani U; Gjerde C; McCoy S; Maddux BA; Hessler D; Goldfine ID; Youngren JF · BMC endocrine disorders · 2013
    Randomized trial31 participantsMetabolism Boost forChromium
  22. Dose-Response Effects of Short-Term Rhodiola rosea (Golden Root Extract) Supplementation on Anaerobic Exercise Performance and Cognitive Function in Resistance-Trained Athletes: A Randomized, Crossover, Double-Blind, and Placebo-Controlled Study.
    Koozehchian MS; Newton AT; Mabrey G; Bonness FM; Rafajlovska R; Naderi A · Nutrients · 2025
    Randomized trial27 participantsBrain Health Fitness forRhodiola
  23. A combination of green tea, rhodiola, magnesium and B vitamins modulates brain activity and protects against the effects of induced social stress in healthy volunteers.
    Boyle NB; Billington J; Lawton C; Quadt F; Dye L · Nutritional neuroscience · 2022
    Randomized trial100 participantsBrain Health forRhodiola
  24. Rosenroot (Rhodiola rosea): traditional use, chemical composition, pharmacology and clinical efficacy.
    Panossian A; Wikman G; Sarris J · Phytomedicine : international journal of phytotherapy and phytopharmacology · 2010
    Narrative reviewBrain Health forRhodiola
  25. Rhodiola rosea in stress induced fatigue--a double blind cross-over study of a standardized extract SHR-5 with a repeated low-dose regimen on the mental performance of healthy physicians during night duty.
    Darbinyan V; Kteyan A; Panossian A; Gabrielian E; Wikman G; Wagner H · Phytomedicine : international journal of phytotherapy and phytopharmacology · 2001
    Randomized trial56 participantsBrain Health General Health Productivity Boost forRhodiola
  26. Effects of a Rhodiola rosea extract on mental resource allocation and attention: An event-related potential dual task study.
    Koop T; Dienel A; Heldmann M; Münte TF · Phytotherapy research : PTR · 2021
    Single-arm trial50 participantsBrain Health Cognitive Support forRhodiola
  27. Combined L-carnosine and L-tyrosine supplementation as an ergogenic strategy for physical and cognitive performance under fatigue in professional football players.
    Bilgin S; Bozyılan E; Buzdağlı Y; Karaç Öcal Y; Gürkan O; Toktaş S; İnan H; Egil İ; Yarayan YE · Frontiers in nutrition · 2026
    Randomized trial24 participantsBrain Health forTyrosine
  28. Effect of tyrosine supplementation on clinical and healthy populations under stress or cognitive demands--A review.
    Jongkees BJ; Hommel B; Kühn S; Colzato LS · Journal of psychiatric research · 2016
    Narrative reviewBrain Health forTyrosine
  29. Influence of nutritional tyrosine on cognition and functional connectivity in healthy old humans.
    Hensel C; Becker M; Düzel S; Demuth I; Norman K; Steinhagen-Thiessen E; Gallinat J; Lindenberger U; Kühn S · NeuroImage · 2019
    Cross-sectional study286 participantsBrain Health forTyrosine
  30. Dietary Tyrosine Intake (FFQ) Is Associated with Locus Coeruleus, Attention and Grey Matter Maintenance: An MRI Structural Study on 398 Healthy Individuals of the Berlin Aging Study-II.
    Plini ERG; Melnychuk MC; Harkin A; Dahl MJ; McAuslan M; Kühn S; Boyle RT; Whelan R; Andrews R; Düzel S; Drewelies J; Wagner GG; Lindenberger U; Norman K; Robertson IH; Dockree PM · The journal of nutrition, health & aging · 2023
    Cross-sectional study398 participantsBrain Health forTyrosine
  31. Baseline-dependent effect of dopamine's precursor L-tyrosine on working memory gating but not updating.
    Jongkees BJ · Cognitive, affective & behavioral neuroscience · 2021
    Randomized trial45 participantsBrain Health forTyrosine
  32. Central additive effect of Ginkgo biloba and Rhodiola rosea on psychomotor vigilance task and short-term working memory accuracy.
    Al-Kuraishy HM · Journal of intercultural ethnopharmacology · 2016
    Clinical trial112 participantsCognitive Support forRhodiola
  33. Clinical evidence for the adaptogenic effects of Withania somnifera and Rhodiola rosea - A systematic review with molecular interpretation of psychometric outcomes.
    Łuszczak J; Kocki J · Annals of agricultural and environmental medicine : AAEM · 2026
    Systematic review19 studies pooledCognitive Support forRhodiola
  34. A randomised, double-blind, placebo-controlled, parallel-group study of the standardised extract shr-5 of the roots of Rhodiola rosea in the treatment of subjects with stress-related fatigue.
    Olsson EM; von Schéele B; Panossian AG · Planta medica · 2009
    Randomized trial60 participantsCognitive Support Productivity Boost forRhodiola
  35. Cognitive and mood improvements of caffeine in habitual consumers and habitual non-consumers of caffeine.
    Haskell CF; Kennedy DO; Wesnes KA; Scholey AB · Psychopharmacology · 2005
    Randomized trial48 participantsEnergy forCaffeine
  36. Caffeine-containing energy drink improves physical performance of elite rugby players during a simulated match.
    Del Coso J; Ramírez JA; Muñoz G; Portillo J; Gonzalez-Millán C; Muñoz V; Barbero-Álvarez JC; Muñoz-Guerra J · Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme · 2016
    Randomized trial26 participantsEnergy forCaffeine
  37. Does Single or Combined Caffeine and Taurine Supplementation Improve Athletic and Cognitive Performance without Affecting Fatigue Level in Elite Boxers? A Double-Blind, Placebo-Controlled Study.
    Ozan M; Buzdagli Y; Eyipinar CD; Baygutalp NK; Yüce N; Oget F; Kan E; Baygutalp F · Nutrients · 2022
    Randomized trial20 participantsEnergy forCaffeine
  38. Trait Energy and Fatigue Modify the Effects of Caffeine on Mood, Cognitive and Fine-Motor Task Performance: A Post-Hoc Study.
    Fuller DT; Smith ML; Boolani A · Nutrients · 2021
    Randomized trialEnergy forCaffeine
  39. Acute Effect of Citrulline Malate on Repetition Performance During Strength Training: A Systematic Review and Meta-Analysis.
    Vårvik FT; Bjørnsen T; Gonzalez AM · International journal of sport nutrition and exercise metabolism · 2021
    Meta-analysis137 participants8 studies pooledEnergy forCitrulline
  40. Oral L-citrulline supplementation enhances cycling time trial performance in healthy trained men: Double-blind randomized placebo-controlled 2-way crossover study.
    Suzuki T; Morita M; Kobayashi Y; Kamimura A · Journal of the International Society of Sports Nutrition · 2016
    Randomized trial22 participantsEnergy forCitrulline
  41. Citrulline malate enhances athletic anaerobic performance and relieves muscle soreness.
    Pérez-Guisado J; Jakeman PM · Journal of strength and conditioning research · 2010
    Randomized trial41 participantsEnergy forCitrulline
  42. Citrulline/malate promotes aerobic energy production in human exercising muscle.
    Bendahan D; Mattei JP; Ghattas B; Confort-Gouny S; Le Guern ME; Cozzone PJ · British journal of sports medicine · 2002
    Single-arm trial18 participantsEnergy forCitrulline
  43. The Effect of Citrulline Malate Supplementation on Muscle Fatigue Among Healthy Participants.
    Farney TM; Bliss MV; Hearon CM; Salazar DA · Journal of strength and conditioning research · 2019
    Randomized trial12 participantsEnergy forCitrulline
  44. Effects of Coenzyme Q10 on Statin-Induced Myopathy: An Updated Meta-Analysis of Randomized Controlled Trials.
    Qu H; Guo M; Chai H; Wang WT; Gao ZY; Shi DZ · Journal of the American Heart Association · 2019
    Meta-analysis575 participants12 studies pooledEnergy forCoenzyme Q-10
  45. Coenzyme Q10 Supplementation in Athletes: A Systematic Review.
    Fernandes MSS; Fidelis DEDS; Aidar FJ; Badicu G; Greco G; Cataldi S; Santos GCJ; de Souza RF; Ardigò LP · Nutrients · 2026
    Systematic review16 studies pooledEnergy forCoenzyme Q-10
  46. Effectiveness of Coenzyme Q10 Supplementation for Reducing Fatigue: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
    Tsai IC; Hsu CW; Chang CH; Tseng PT; Chang KV · Frontiers in pharmacology · 2024
    Meta-analysis1,126 participants13 studies pooledEnergy forCoenzyme Q-10
  47. Antifatigue effects of coenzyme Q10 during physical fatigue.
    Mizuno K; Tanaka M; Nozaki S; Mizuma H; Ataka S; Tahara T; Sugino T; Shirai T; Kajimoto Y; Kuratsune H; Kajimoto O; Watanabe Y · Nutrition (Burbank, Los Angeles County, Calif.) · 2008
    Randomized trial17 participantsEnergy forCoenzyme Q-10
  48. Effect of coenzyme Q10 supplementation on fatigue: A systematic review of interventional studies.
    Mehrabani S; Askari G; Miraghajani M; Tavakoly R; Arab A · Complementary therapies in medicine · 2019
    Systematic review16 studies pooledEnergy forCoenzyme Q-10
  49. The effect of eight weeks of supplementation with Eleutherococcus senticosus on endurance capacity and metabolism in human
    J Kuo, K W Chen, I S Cheng, P H Tsai, Y J Lu, N Y Lee · Chinese Journal of Physiology · 2010
    Randomized trial9 participantsEnergy forEleuthero
  50. Purified dry extract of Paullinia cupana (guaraná) (PC-18) for chemotherapy-related fatigue in patients with solid tumors: an early discontinuation study.
    del Giglio AB; Cubero Dde I; Lerner TG; Guariento RT; de Azevedo RG; Paiva H; Goldman C; Carelli B; Cruz FM; Schindler F; Pianowski L; de Matos LL; del Giglio A · Journal of dietary supplements · 2014
    Randomized trial40 participantsEnergy forGuarana
  51. Placebo-Controlled, Double-Blind, Randomized Study of a Dry Guarana Extract in Patients with Head and Neck Tumors Undergoing Chemoradiotherapy: Effects on Fatigue and Quality of Life.
    Martins SPDS; Ferreira CL; Del Giglio A · Journal of dietary supplements · 2019
    Randomized trial60 participantsEnergy forGuarana
  52. Effectiveness of guaraná (Paullinia cupana) for postradiation fatigue and depression: results of a pilot double-blind randomized study.
    da Costa Miranda V; Trufelli DC; Santos J; Campos MP; Nobuo M; da Costa Miranda M; Schlinder F; Riechelmann R; del Giglio A · Journal of alternative and complementary medicine (New York, N.Y.) · 2009
    Randomized trial36 participantsEnergy forGuarana
  53. Magnesium-L-threonate improves sleep quality and daytime functioning in adults with self-reported sleep problems: A randomized controlled trial.
    Hausenblas HA; Lynch T; Hooper S; Shrestha A; Rosendale D; Gu J · Sleep medicine: X · 2025
    Randomized trial80 participantsEnergy forMagnesium
  54. Total magnesium intake and risk of frailty in older women.
    Struijk EA; Fung TT; Bischoff-Ferrari HA; Willett WC; Lopez-Garcia E · Journal of cachexia, sarcopenia and muscle · 2024
    Cohort study81,524 participantsEnergy forMagnesium
  55. Red blood cell magnesium and chronic fatigue syndrome.
    Cox IM; Campbell MJ; Dowson D · Lancet (London, England) · 1991
    Randomized trial32 participantsEnergy forMagnesium
  56. Exercise, magnesium and immune function.
    Laires MJ; Monteiro C · Magnesium research · 2008
    Narrative reviewEnergy forMagnesium
  57. The Effect of Short-Term Rhodiola rosea Supplementation on Simulated Game Time, Perceived Fatigue, and Performance in Basketball Players.
    Wang J; Zhao H; Yu L; Zhao K; Jiang W; Liu S; Dai J; Xu L; Sun P; Yun H; Liu C · Nutrients · 2025
    Randomized trial48 participantsEnergy Fitness forRhodiola
  58. Effects of Rhodiola rosea on Physical and Decision-Making Performance in Football Players: A Randomised Controlled Trial.
    Dou Y; Wang Y; Zhang W; Jiang Y; Zhang J; Yang T; Han Z; Li Y; Liu C; Ren D · Nutrients · 2026
    Randomized trial24 participantsEnergy Fitness forRhodiola
  59. Combined Effects of Rhodiola Rosea and Caffeine Supplementation on Straight Punch Explosive Power in Untrained and Trained Boxing Volunteers: A Synergistic Approach.
    Tao B; Sun H; Li H; Xu Z; Xu Y; Chen L; Ma C; Zhang X; Yu L; Bao S; Liu C · Metabolites · 2025
    Randomized trial96 participantsEnergy forRhodiola
  60. Rhodiola rosea in Subjects with Prolonged or Chronic Fatigue Symptoms: Results of an Open-Label Clinical Trial.
    Lekomtseva Y; Zhukova I; Wacker A · Complementary medicine research · 2019
    Single-arm trial100 participantsEnergy General Health forRhodiola
  61. Combined Rhodiola rosea and eccentric training boost endurance performance and lower-limb reactive strength in recreationally active women.
    Wang IL; Su Y; Zhang L; Tang M; Chen YM · Frontiers in physiology · 2025
    Randomized trial30 participantsEnergy Fitness forRhodiola
  62. A new perspective on vitamin B12 deficiency in rheumatology: a case-based review.
    Dułak NA; Rytlewska M; Jaskólska M; Chmielewski M · Rheumatology international · 2024
    Case series3 participantsEnergy forVitamin B12
  63. Effects of Vitamin B12 Supplementation on Cognitive Function, Depressive Symptoms, and Fatigue: A Systematic Review, Meta-Analysis, and Meta-Regression.
    Markun S; Gravestock I; Jäger L; Rosemann T; Pichierri G; Burgstaller JM · Nutrients · 2021
    Meta-analysis6,276 participants16 studies pooledEnergy forVitamin B12
  64. Cobalamin deficiency: clinical picture and radiological findings.
    Briani C; Dalla Torre C; Citton V; Manara R; Pompanin S; Binotto G; Adami F · Nutrients · 2014
    Narrative reviewEnergy forVitamin B12
  65. Vitamin B12 Deficiency: Common Questions and Answers.
    Patel H; McGuirk R · American family physician · 2025
    Narrative reviewEnergy forVitamin B12
  66. Effect of caffeine ingestion on cycling performance: a systematic review and meta-analysis.
    Wu J; Xu K; Yin M; Ding X; Wang T; Zhang Q; Wu X; Xiao N · Frontiers in nutrition · 2026
    Meta-analysis226 participants20 studies pooledFitness forCaffeine
  67. Effects of Caffeine Intake on Endurance Running Performance and Time to Exhaustion: A Systematic Review and Meta-Analysis.
    Wang Z; Qiu B; Gao J; Del Coso J · Nutrients · 2023
    Meta-analysis254 participants21 studies pooledFitness forCaffeine
  68. Acute Effects of Caffeine Supplementation on Movement Velocity in Resistance Exercise: A Systematic Review and Meta-analysis.
    Raya-González J; Rendo-Urteaga T; Domínguez R; Castillo D; Rodríguez-Fernández A; Grgic J · Sports medicine (Auckland, N.Z.) · 2021
    Meta-analysis12 studies pooledFitness forCaffeine
  69. Sex Differences in the Ergogenic Response of Acute Caffeine Intake on Muscular Strength, Power and Endurance Performance in Resistance-Trained Individuals: A Randomized Controlled Trial.
    Montalvo-Alonso JJ; Ferragut C; Del Val-Manzano M; Valadés D; Roberts J; Pérez-López A · Nutrients · 2024
    Randomized trial76 participantsFitness forCaffeine
  70. Can I Have My Coffee and Drink It? A Systematic Review and Meta-analysis to Determine Whether Habitual Caffeine Consumption Affects the Ergogenic Effect of Caffeine.
    Carvalho A; Marticorena FM; Grecco BH; Barreto G; Saunders B · Sports medicine (Auckland, N.Z.) · 2022
    Meta-analysis60 studies pooledFitness forCaffeine
  71. The Effects of Combined Exercise with Citrulline Supplementation on Body Composition and Lower Limb Function of Overweight Older Adults: A Systematic Review and Meta-Analysis.
    Xie S; Li S; Shaharudin S · Journal of sports science & medicine · 2023
    Meta-analysis303 participants7 studies pooledFitness forCitrulline
  72. Effect of High-Intensity Interval Training Combined with L-Citrulline Supplementation on Functional Capacities and Muscle Function in Dynapenic-Obese Older Adults.
    Buckinx F; Gouspillou G; Carvalho LP; Marcangeli V; El Hajj Boutros G; Dulac M; Noirez P; Morais JA; Gaudreau P; Aubertin-Leheudre M · Journal of clinical medicine · 2020
    Randomized trial56 participantsFitness forCitrulline
  73. Initial Dietary Protein Intake Influence Muscle Function Adaptations in Older Men and Women Following High-Intensity Interval Training Combined with Citrulline.
    Buckinx F; Marcangeli V; Pinheiro Carvalho L; Dulac M; Hajj Boutros G; Gouspillou G; Gaudreau P; Morais J; Noirez P; Aubertin-Leheudre M · Nutrients · 2020
    Randomized trial73 participantsFitness forCitrulline
  74. Effects of Citrulline alone or combined with exercise on muscle mass, muscle strength, and physical performance among older adults: a systematic review.
    Aubertin-Leheudre M; Buckinx F · Current opinion in clinical nutrition and metabolic care · 2021
    Systematic review250 participants6 studies pooledFitness forCitrulline
  75. Combined Vs. Single Supplementation of L-Citrulline and Sodium Bicarbonate During Sprint Interval Training in Basketball Players: Effects on Physical Performance and Hormonal Adaptations.
    Wang Y; Wang Y; Qian K · Journal of sports science & medicine · 2025
    Randomized trial40 participantsFitness forCitrulline
  76. A systematic review and meta-analysis of propionyl-L-carnitine effects on exercise performance in patients with claudication.
    Brass EP; Koster D; Hiatt WR; Amato A · Vascular medicine (London, England) · 2013
    Meta-analysis13 studies pooledFitness forL-Carnitine
  77. Oral acetyl-L-carnitine therapy reduces fatigue in overt hepatic encephalopathy: a randomized, double-blind, placebo-controlled study.
    Malaguarnera M; Vacante M; Giordano M; Pennisi G; Bella R; Rampello L; Malaguarnera M; Li Volti G; Galvano F · The American journal of clinical nutrition · 2011
    Randomized trial121 participantsFitness forL-Carnitine
  78. Prolonged oral L-carnitine substitution increases bicycle ergometer performance in patients with severe, ischemically induced cardiac insufficiency.
    Löster H; Miehe K; Punzel M; Stiller O; Pankau H; Schauer J · Cardiovascular drugs and therapy · 2000
    Randomized trial41 participantsFitness forL-Carnitine
  79. L-Carnitine treatment reduces severity of physical and mental fatigue and increases cognitive functions in centenarians: a randomized and controlled clinical trial.
    Malaguarnera M; Cammalleri L; Gargante MP; Vacante M; Colonna V; Motta M · The American journal of clinical nutrition · 2008
    Randomized trial66 participantsFitness forL-Carnitine
  80. Effects of nine weeks L-Carnitine supplementation on exercise performance, anaerobic power, and exercise-induced oxidative stress in resistance-trained males.
    Koozehchian MS; Daneshfar A; Fallah E; Agha-Alinejad H; Samadi M; Kaviani M; Kaveh B M; Jung YP; Sablouei MH; Moradi N; Earnest CP; Chandler TJ; Kreider RB · Journal of exercise nutrition & biochemistry · 2020
    Randomized trial23 participantsFitness forL-Carnitine
  81. The Impact of Rhodiola Rosea Extract on Strength Performance in Alternative Bench-Press and Bench-Pull Exercises Under Resting and Mental Fatigue Conditions: A Randomized, Triple-Blinded, Placebo-Controlled, Crossover Trial.
    Marcos-Frutos D; Leban Ž; Li Z; Zhang X; Lara PM; Alix-Fages C; Jiménez-Martínez P; Zebboudji N; Caillet A; Redondo B; Vera J; Janicijevic D; García-Ramos A · Nutrients · 2025
    Randomized trial18 participantsFitness forRhodiola
  82. Taurine supplementation enhances anaerobic power in elite speed skaters: A double-blind, randomized, placebo-controlled, crossover study.
    Buzdağlı Y; Eyipınar CD; Öget F; Şıktar E; Forbes SC; Tekin A · Biology of sport · 2023
    Randomized trial30 participantsFitness forTaurine
  83. The effect of acute taurine ingestion on 3-km running performance in trained middle-distance runners.
    Balshaw TG; Bampouras TM; Barry TJ; Sparks SA · Amino acids · 2013
    Randomized trial8 participantsFitness forTaurine
  84. Effects of different doses of taurine supplementation on repeated-sprint performance after exhaustive exercise in a high temperature and humidity environment.
    Cheng X; Lin Y; Li Z · Frontiers in nutrition · 2026
    Randomized trial16 participantsFitness forTaurine
  85. Oral taurine improves critical power and severe-intensity exercise tolerance.
    Waldron M; Patterson SD; Jeffries O · Amino acids · 2020
    Randomized trial12 participantsFitness forTaurine
  86. Acute taurine supplementation enhances thermoregulation and endurance cycling performance in the heat.
    Page LK; Jeffries O; Waldron M · European journal of sport science · 2019
    Randomized trial11 participantsFitness forTaurine
  87. Perioperative systemic magnesium to minimize postoperative pain: a meta-analysis of randomized controlled trials.
    De Oliveira GS; Castro-Alves LJ; Khan JH; McCarthy RJ · Anesthesiology · 2013
    Meta-analysis1,257 participants20 studies pooledGeneral Health forMagnesium
  88. Long-term outcome after intravenous magnesium sulphate in suspected acute myocardial infarction: the second Leicester Intravenous Magnesium Intervention Trial (LIMIT-2).
    Woods KL; Fletcher S · Lancet (London, England) · 1994
    Randomized trial2,316 participantsGeneral Health forMagnesium
  89. Association of magnesium sulfate use with mortality in critically ill patients with sepsis: a retrospective propensity score-matched cohort study.
    Gu WJ; Duan XJ; Liu XZ; Cen Y; Tao LY; Lyu J; Yin HY · British journal of anaesthesia · 2023
    Cohort study10,999 participantsGeneral Health forMagnesium
  90. Hypomagnesemia and Mortality in Incident Hemodialysis Patients.
    Li L; Streja E; Rhee CM; Mehrotra R; Soohoo M; Brunelli SM; Kovesdy CP; Kalantar-Zadeh K · American journal of kidney diseases : the official journal of the National Kidney Foundation · 2016
    Cohort study9,359 participantsGeneral Health forMagnesium
  91. The effects of magnesium supplementation on abnormal uterine bleeding, alopecia, quality of life, and acne in women with polycystic ovary syndrome: a randomized clinical trial.
    Jaripur M; Ghasemi-Tehrani H; Askari G; Gholizadeh-Moghaddam M; Clark CCT; Rouhani MH · Reproductive biology and endocrinology : RB&E · 2022
    Randomized trial64 participantsGeneral Health forMagnesium
  92. Actaea racemosa L. Is More Effective in Combination with Rhodiola rosea L. for Relief of Menopausal Symptoms: A Randomized, Double-Blind, Placebo-Controlled Study.
    Pkhaladze L; Davidova N; Khomasuridze A; Shengelia R; Panossian AG · Pharmaceuticals (Basel, Switzerland) · 2024
    Randomized trial220 participantsGeneral Health forRhodiola
  93. A double-blind, placebo-controlled pilot study of the stimulating and adaptogenic effect of Rhodiola rosea SHR-5 extract on the fatigue of students caused by stress during an examination period with a repeated low-dose regimen.
    Spasov AA; Wikman GK; Mandrikov VB; Mironova IA; Neumoin VV · Phytomedicine : international journal of phytotherapy and phytopharmacology · 2000
    Randomized trialGeneral Health Productivity Boost forRhodiola
  94. [The effect of the preparation rodakson on the psychophysiological and physical adaptation of students to an academic load].
    Spasov AA; Mandrikov VB; Mironova IA · Eksperimental'naia i klinicheskaia farmakologiia · 2000
    Clinical trialGeneral Health forRhodiola
  95. Cognitive Effects of Taurine and Related Sulphur-Containing Amino Acids: A Systematic Review of Human Trials and Considerations for Plant-Based Dietary Transitions.
    Moore JA; Cousins AL; Taylor RMJ; Griffiths AR; Young HA · Foods (Basel, Switzerland) · 2026
    Systematic review244 participants8 studies pooledGeneral Health forTaurine
  96. Association between habitual dietary taurine intake and the risk of metabolic dysfunction-associated steatotic liver disease: a prospective cohort study.
    Zhang S; Xu X; Wang D; Gu Y; Wu H; Meng G; Zhang Q; Liu L; Borné Y; Niu K; Bai L · Food & function · 2026
    Cohort study16,699 participantsGeneral Health forTaurine
  97. Effects of Oral Taurine Supplementation on Cardiometabolic Risk Factors: A Meta-analysis and Systematic Review of Randomized Clinical Trials.
    Nie Z; Liu Y; Zhang M; Wu C; Cao Q; Xu J; Zheng Y; Min Z; Zhang W; Han S · Nutrition reviews · 2025
    Meta-analysis34 studies pooledGeneral Health forTaurine
  98. Oral Vitamin B12 versus Placebo for the Prevention of Chemotherapy-Induced Peripheral Neuropathy in Gynecological Cancer Patients: A Randomized, Double-Blind, Placebo-Controlled Trial.
    Insin P; Chaiwongsa T; Prueksaritanond N · Asian Pacific journal of cancer prevention : APJCP · 2026
    Randomized trial40 participantsGeneral Health forVitamin B12
  99. Vitamin B12 Supplementation in Diabetic Neuropathy: A 1-Year, Randomized, Double-Blind, Placebo-Controlled Trial.
    Didangelos T; Karlafti E; Kotzakioulafi E; Margariti E; Giannoulaki P; Batanis G; Tesfaye S; Kantartzis K · Nutrients · 2021
    Randomized trial90 participantsGeneral Health forVitamin B12
  100. A single-center randomized controlled trial of local methylcobalamin injection for subacute herpetic neuralgia.
    Xu G; Lv ZW; Feng Y; Tang WZ; Xu GX · Pain medicine (Malden, Mass.) · 2014
    Randomized trial98 participantsGeneral Health forVitamin B12
  101. Local Injection of Methylcobalamin Combined with Lidocaine for Acute Herpetic Neuralgia.
    Xǔ G; Xu S; Tang WZ; Xú G; Cheng C; Xu J · Pain medicine (Malden, Mass.) · 2017
    Randomized trial204 participantsGeneral Health forVitamin B12
  102. The Effect of Vitamin B12 and Folic Acid Supplementation on Serum Homocysteine, Anemia Status and Quality of Life of Patients with Multiple Sclerosis.
    Nozari E; Ghavamzadeh S; Razazian N · Clinical nutrition research · 2022
    Clinical trial50 participantsGeneral Health forVitamin B12
  103. Performance and alertness effects of caffeine, dextroamphetamine, and modafinil during sleep deprivation.
    Wesensten NJ; Killgore WD; Balkin TJ · Journal of sleep research · 2006
    Randomized trial48 participantsMental Focus forCaffeine
  104. Effects of caffeine on mood and performance: a study of realistic consumption.
    Brice CF; Smith AP · Psychopharmacology · 2003
    Clinical trial24 participantsMental Focus forCaffeine
  105. Effects of caffeine or diphenhydramine on visual vigilance.
    Fine BJ; Kobrick JL; Lieberman HR; Marlowe B; Riley RH; Tharion WJ · Psychopharmacology · 1995
    Randomized trial24 participantsMental Focus forCaffeine
  106. A Randomized Study to Examine the Ability of a Caffeine-Based Energy Drink to Impact Energy Expenditure, Fat Oxidation, and Cognitive Performance.
    Krieger J; Schrautemeier A; Hagele A; Gaige C; Mennemeyer O; Tolbert S; Iannotti J; Kerksick C; Noonan C; Mumford P · Nutrients · 2025
    Randomized trial60 participantsMetabolism Boost forCaffeine
  107. Oolong tea increases metabolic rate and fat oxidation in men.
    Rumpler W; Seale J; Clevidence B; Judd J; Wiley E; Yamamoto S; Komatsu T; Sawaki T; Ishikura Y; Hosoda K · The Journal of nutrition · 2001
    Randomized trial12 participantsMetabolism Boost forCaffeine
  108. Effect of caffeine intake on fat oxidation rate during exercise: is there a dose-response effect?
    Gutiérrez-Hellín J; Aguilar-Navarro M; Ruiz-Moreno C; Muñoz A; Varillas-Delgado D; Amaro-Gahete FJ; Del Coso J · European journal of nutrition · 2023
    Randomized trial18 participantsMetabolism Boost forCaffeine
  109. Comparison of changes in energy expenditure and body temperatures after caffeine consumption.
    Koot P; Deurenberg P · Annals of nutrition & metabolism · 1995
    Randomized trial12 participantsMetabolism Boost forCaffeine
  110. Caffeine Increases Work Done above Critical Power, but Not Anaerobic Work.
    Silveira R; Andrade-Souza VA; Arcoverde L; Tomazini F; Sansonio A; Bishop DJ; Bertuzzi R; Lima-Silva AE · Medicine and science in sports and exercise · 2018
    Randomized trial9 participantsMetabolism Boost forCaffeine
  111. Elevated intakes of supplemental chromium improve glucose and insulin variables in individuals with type 2 diabetes.
    Anderson RA; Cheng N; Bryden NA; Polansky MM; Cheng N; Chi J; Feng J · Diabetes · 1997
    Randomized trial180 participantsMetabolism Boost forChromium
  112. Chromium Supplementation and the Effects on Metabolic Status in Women with Polycystic Ovary Syndrome: A Randomized, Double-Blind, Placebo-Controlled Trial.
    Jamilian M; Asemi Z · Annals of nutrition & metabolism · 2016
    Randomized trial64 participantsMetabolism Boost forChromium
  113. A Comprehensive insight into the effect of chromium supplementation on oxidative stress indices in diabetes mellitus: A systematic review.
    Kooshki F; Tutunchi H; Vajdi M; Karimi A; Niazkar HR; Shoorei H; Pourghassem Gargari B · Clinical and experimental pharmacology & physiology · 2024
    Systematic review33 studies pooledMetabolism Boost forChromium
  114. [Chromium supplementation in patients with type 2 diabetes and high risk of type 2 diabetes: a meta-analysis of randomized controlled trials].
    San Mauro-Martin I; Ruiz-León AM; Camina-Martín MA; Garicano-Vilar E; Collado-Yurrita L; Mateo-Silleras Bd; Redondo Del Río Mde P · Nutricion hospitalaria · 2017
    Meta-analysis13 studies pooledMetabolism Boost forChromium
  115. Coenzyme Q10 supplementation improves adipokine profile in dyslipidemic individuals: a randomized controlled trial.
    Zhang P; Chen K; He T; Guo H; Chen X · Nutrition & metabolism · 2022
    Randomized trial101 participantsMetabolism Boost forCoenzyme Q-10
  116. Ubiquinol supplementation modulates energy metabolism and bone turnover during high intensity exercise.
    Diaz-Castro J; Mira-Rufino PJ; Moreno-Fernandez J; Chirosa I; Chirosa JL; Guisado R; Ochoa JJ · Food & function · 2021
    Randomized trial100 participantsMetabolism Boost forCoenzyme Q-10
  117. Effects of Coenzyme Q10 on Lipid, Glycemic, and Inflammatory Markers in Metabolic Disorders: A Systematic Review and Meta-Analysis.
    Zhang Z; Liu Z; Geng Y; Huang Y; Hu R; Li F; Song Y; Zhang M · Journal of diabetes research · 2026
    Meta-analysis3,422 participants64 studies pooledMetabolism Boost forCoenzyme Q-10
  118. The effect of coenzyme Q10 intake on metabolic profiles in women candidates for in-vitro fertilization: a randomised trial.
    Ahmadi Asouri S; Asemi R; Aghadavod E; Jamilian M · Annals of medicine and surgery (2012) · 2024
    Randomized trial40 participantsMetabolism Boost forCoenzyme Q-10
  119. Effect of green tea on glucose control and insulin sensitivity: a meta-analysis of 17 randomized controlled trials.
    Liu K; Zhou R; Wang B; Chen K; Shi LY; Zhu JD; Mi MT · The American journal of clinical nutrition · 2013
    Meta-analysis1,133 participants17 studies pooledMetabolism Boost forGreen Tea
  120. Green tea extract ingestion, fat oxidation, and glucose tolerance in healthy humans.
    Venables MC; Hulston CJ; Cox HR; Jeukendrup AE · The American journal of clinical nutrition · 2008
    Randomized trial23 participantsMetabolism Boost forGreen Tea
  121. Efficacy of a green tea extract rich in catechin polyphenols and caffeine in increasing 24-h energy expenditure and fat oxidation in humans.
    Dulloo AG; Duret C; Rohrer D; Girardier L; Mensi N; Fathi M; Chantre P; Vandermander J · The American journal of clinical nutrition · 1999
    Randomized trial10 participantsMetabolism Boost forGreen Tea
  122. A 60-Day Green Tea Extract Supplementation Counteracts the Dysfunction of Adipose Tissue in Overweight Post-Menopausal and Class I Obese Women.
    Rondanelli M; Gasparri C; Perna S; Petrangolini G; Allegrini P; Fazia T; Bernardinelli L; Cavioni A; Mansueto F; Oberto L; Patelli Z; Tartara A; Riva A · Nutrients · 2022
    Randomized trial28 participantsMetabolism Boost forGreen Tea
  123. Epigallocatechin gallate alleviates non-alcoholic fatty liver disease through the inhibition of the expression and activity of Dipeptide kinase 4.
    Yang M; Yan R; Sha R; Wang X; Zhou S; Li B; Zheng Q; Cao Y · Clinical nutrition (Edinburgh, Scotland) · 2024
    Randomized trialMetabolism Boost forGreen Tea
  124. Iodine Supplementation Decreases Hypercholesterolemia in Iodine-Deficient, Overweight Women: A Randomized Controlled Trial.
    Herter-Aeberli I; Cherkaoui M; El Ansari N; Rohner R; Stinca S; Chabaa L; von Eckardstein A; Aboussad A; Zimmermann MB · The Journal of nutrition · 2015
    Randomized trial163 participantsMetabolism Boost forIodine
  125. Effect of oral iodized oil on thyroid size and thyroid hormone metabolism in children with concurrent selenium and iodine deficiency.
    Zimmermann MB; Adou P; Torresani T; Zeder C; Hurrell RF · European journal of clinical nutrition · 2000
    Single-arm trial51 participantsMetabolism Boost forIodine
  126. Serum Iodine Concentration as a Biomarker for Individual Iodine Nutrition and Thyroid Function in Pregnant Women: A Cross-Sectional Study in Hubei Province.
    Xu M; Dai X; Wang Z; Guo C; Zhang B; Guo H · Public health nutrition · 2026
    Cross-sectional study1,197 participantsMetabolism Boost forIodine
  127. Iron status influences the efficacy of iodine prophylaxis in goitrous children in Côte d'Ivoire.
    Zimmermann MB · International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition · 2002
    OtherMetabolism Boost forIodine
  128. Persistence of goiter despite oral iodine supplementation in goitrous children with iron deficiency anemia in Côte d'Ivoire.
    Zimmermann M; Adou P; Torresani T; Zeder C; Hurrell R · The American journal of clinical nutrition · 2000
    Non-randomized trial109 participantsMetabolism Boost forIodine
  129. Association of magnesium consumption with type 2 diabetes and glucose metabolism: A systematic review and pooled study with trial sequential analysis.
    Zhao B; Deng H; Li B; Chen L; Zou F; Hu L; Wei Y; Zhang W · Diabetes/metabolism research and reviews · 2021
    Meta-analysis1,168 participants26 studies pooledMetabolism Boost forMagnesium
  130. Magnesium supplementation for glycemic status in women with gestational diabetes: a systematic review and meta-analysis.
    Tan X; Huang Y · Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology · 2022
    Meta-analysis4 studies pooledMetabolism Boost forMagnesium
  131. Impact of oral magnesium supplementation on glycemic and cardiometabolic outcomes in prediabetic adults: a systematic review and meta-analysis.
    Basit A; Kumar S; Ahmed H; Babar R; Saeed SS; Siddiqui TA; Khan S; Saeed A; Khan M; Hanif H; Fasih A; Shabbir S; Kumar H; Kumar L; Raja A; Kumar S; Chander S · Journal of diabetes and metabolic disorders · 2026
    Meta-analysis384 participants5 studies pooledMetabolism Boost forMagnesium
  132. Oral magnesium supplementation improves insulin sensitivity and metabolic control in type 2 diabetic subjects: a randomized double-blind controlled trial.
    Rodríguez-Morán M; Guerrero-Romero F · Diabetes care · 2003
    Randomized trial63 participantsMetabolism Boost forMagnesium
  133. Magnesium Supplementation and the Effects on Wound Healing and Metabolic Status in Patients with Diabetic Foot Ulcer: a Randomized, Double-Blind, Placebo-Controlled Trial.
    Razzaghi R; Pidar F; Momen-Heravi M; Bahmani F; Akbari H; Asemi Z · Biological trace element research · 2018
    Randomized trial70 participantsMetabolism Boost forMagnesium
  134. Effects of caffeine on alertness.
    Zwyghuizen-Doorenbos A; Roehrs TA; Lipschutz L; Timms V; Roth T · Psychopharmacology · 1990
    Randomized trial24 participantsProductivity Boost forCaffeine
  135. Effects of Different Sources of Low-Dose Caffeine on Mood/Arousal and Cognitive Performance.
    Irwin C; McCartney D; Grant G; Delang N; Bartrim K; Cox GR; Desbrow B · Perceptual and motor skills · 2023
    Randomized trial22 participantsProductivity Boost forCaffeine
  136. Effects of caffeine, sleep loss, and stress on cognitive performance and mood during U.S. Navy SEAL training. Sea-Air-Land.
    Lieberman HR; Tharion WJ; Shukitt-Hale B; Speckman KL; Tulley R · Psychopharmacology · 2003
    Randomized trial68 participantsProductivity Boost forCaffeine
  137. A review of caffeine's effects on cognitive, physical and occupational performance.
    McLellan TM; Caldwell JA; Lieberman HR · Neuroscience and biobehavioral reviews · 2017
    Narrative reviewProductivity Boost forCaffeine
  138. Acute caffeine supplementation as a nutrition-based strategy to mitigate sleep-loss-related cognitive and operational performance impairments in military personnel: a systematic review and meta-analysis.
    Wang R; Wang W; Meng L; Hao G; Gu G · Frontiers in nutrition · 2026
    Meta-analysis7 studies pooledProductivity Boost forCaffeine
  139. No benefit adding eleutherococcus senticosus to stress management training in stress-related fatigue/weakness, impaired work or concentration, a randomized controlled study.
    Schaffler K; Wolf OT; Burkart M · Pharmacopsychiatry · 2014
    Randomized trial144 participantsProductivity Boost forEleuthero
  140. Effects of Rhodiola rosea supplementation on mental performance, physical capacity, and oxidative stress biomarkers in healthy men.
    Jówko E; Sadowski J; Długołęcka B; Gierczuk D; Opaszowski B; Cieśliński I · Journal of sport and health science · 2022
    Randomized trial26 participantsProductivity Boost forRhodiola
  141. The Effectiveness of Rhodiola rosea L. Preparations in Alleviating Various Aspects of Life-Stress Symptoms and Stress-Induced Conditions-Encouraging Clinical Evidence.
    Ivanova Stojcheva E; Quintela JC · Molecules (Basel, Switzerland) · 2022
    Narrative reviewProductivity Boost forRhodiola
  142. Changes in caffeine intake and long-term weight change in men and women.
    Lopez-Garcia E; van Dam RM; Rajpathak S; Willett WC; Manson JE; Hu FB · The American journal of clinical nutrition · 2006
    Cohort study58,157 participantsWeight Loss forCaffeine
  143. Does caffeine ingestion before a short-term sprint interval training promote body fat loss?
    Ferreira GA; Felippe LC; Bertuzzi R; Bishop DJ; Ramos IS; De-Oliveira FR; Lima-Silva AE · Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas · 2020
    Randomized trial20 participantsWeight Loss forCaffeine
  144. Eight Weeks of Sprint Interval Training With Adding Caffeine Ingestion Leads to Greater Improvements in Health-Related Physiological Parameters in Obese Male Adults.
    Zhiang J; Song Q · Physiological research · 2026
    Randomized trial30 participantsWeight Loss forCaffeine
  145. Caffeine treatment prevented from weight regain after calorie shifting diet induced weight loss.
    Davoodi SH; Hajimiresmaiel SJ; Ajami M; Mohseni-Bandpei A; Ayatollahi SA; Dowlatshahi K; Javedan G; Pazoki-Toroudi H · Iranian journal of pharmaceutical research : IJPR · 2014
    Non-randomized trial60 participantsWeight Loss forCaffeine
  146. The effects of caffeine intake on weight loss: a systematic review and dos-response meta-analysis of randomized controlled trials.
    Tabrizi R; Saneei P; Lankarani KB; Akbari M; Kolahdooz F; Esmaillzadeh A; Nadi-Ravandi S; Mazoochi M; Asemi Z · Critical reviews in food science and nutrition · 2020
    Meta-analysis606 participants13 studies pooledWeight Loss forCaffeine
  147. The Influences of Chromium Supplementation on Metabolic Status in Patients with Type 2 Diabetes Mellitus and Coronary Heart Disease.
    Farrokhian A; Mahmoodian M; Bahmani F; Amirani E; Shafabakhsh R; Asemi Z · Biological trace element research · 2021
    Randomized trial64 participantsWeight Loss forChromium
  148. Chromium picolinate supplementation attenuates body weight gain and increases insulin sensitivity in subjects with type 2 diabetes.
    Martin J; Wang ZQ; Zhang XH; Wachtel D; Volaufova J; Matthews DE; Cefalu WT · Diabetes care · 2006
    Randomized trial37 participantsWeight Loss forChromium
  149. Chromium picolinate reduces insulin resistance in polycystic ovary syndrome: Randomized controlled trial.
    Ashoush S; Abou-Gamrah A; Bayoumy H; Othman N · The journal of obstetrics and gynaecology research · 2017
    Randomized trial100 participantsWeight Loss forChromium
  150. Chromium supplementation and polycystic ovary syndrome: A systematic review and meta-analysis.
    Fazelian S; Rouhani MH; Bank SS; Amani R · Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) · 2018
    Meta-analysis351 participants7 studies pooledWeight Loss forChromium
  151. Chromium picolinate balances the metabolic and clinical markers in nonalcoholic fatty liver disease: a randomized, double-blind, placebo-controlled trial.
    Kooshki F; Moradi F; Karimi A; Niazkar HR; Khoshbaten M; Maleki V; Pourghassem Gargari B · European journal of gastroenterology & hepatology · 2021
    Randomized trial46 participantsWeight Loss forChromium
  152. A green tea extract high in catechins reduces body fat and cardiovascular risks in humans.
    Nagao T; Hase T; Tokimitsu I · Obesity (Silver Spring, Md.) · 2007
    Randomized trial240 participantsWeight Loss forGreen Tea
  153. Green tea beverages enriched with catechins with a galloyl moiety reduce body fat in moderately obese adults: a randomized double-blind placebo-controlled trial.
    Kobayashi M; Kawano T; Ukawa Y; Sagesaka YM; Fukuhara I · Food & function · 2016
    Randomized trial126 participantsWeight Loss forGreen Tea
  154. Green tea catechin consumption enhances exercise-induced abdominal fat loss in overweight and obese adults.
    Maki KC; Reeves MS; Farmer M; Yasunaga K; Matsuo N; Katsuragi Y; Komikado M; Tokimitsu I; Wilder D; Jones F; Blumberg JB; Cartwright Y · The Journal of nutrition · 2009
    Randomized trial132 participantsWeight Loss forGreen Tea
  155. Effect of Decaffeinated Green Tea Polyphenols on Body Fat and Precocious Puberty in Obese Girls: A Randomized Controlled Trial.
    Xie L; Tang Q; Yao D; Gu Q; Zheng H; Wang X; Yu Z; Shen X · Frontiers in endocrinology · 2022
    Randomized trial62 participantsWeight Loss forGreen Tea
  156. Effectiveness of green tea on weight reduction in obese Thais: A randomized, controlled trial.
    Auvichayapat P; Prapochanung M; Tunkamnerdthai O; Sripanidkulchai BO; Auvichayapat N; Thinkhamrop B; Kunhasura S; Wongpratoom S; Sinawat S; Hongprapas P · Physiology & behavior · 2008
    Randomized trial60 participantsWeight Loss forGreen Tea
  157. Iodine deficiency among Belgian pregnant women not fully corrected by iodine-containing multivitamins: a national cross-sectional survey.
    Vandevijvere S; Amsalkhir S; Mourri AB; Van Oyen H; Moreno-Reyes R · The British journal of nutrition · 2013
    Cross-sectional study1,311 participantsWeight Loss forIodine
  158. Iodine Intake Estimated by 24 h Urine Collection in the Italian Adult Population: 2008-2012 Survey.
    Iacone R; Iaccarino Idelson P; Formisano P; Russo O; Lo Noce C; Donfrancesco C; Macchia PE; Palmieri L; Galeone D; di Lenarda A; Giampaoli S; Strazzullo P · Nutrients · 2021
    Cross-sectional study2,378 participantsWeight Loss forIodine
  159. Iodine intake in adults: Sociodemographic and dietary determinants from a National Health survey.
    Durán-Agüero S; Daga R · Clinical nutrition ESPEN · 2026
    Cross-sectional study1,230 participantsWeight Loss forIodine