Product Image

Bone Strength Collagen Formula

Life Extension
4.7
★ ★ ★ ★ ★
(732 ratings)
Boron 3 mg
Silicon 5 mg
Calcium 300 mg
Product Image
Score76
Useful vitamin D3, magnesium citrate, boron, and moderate calcium support bone health, but the collagen name is not matched by listed collagen.
How scoring works
Quantity:120 Capsule(s) • (30 servings)
Goals:
General Health
Bone Health
Testosterone Support

Score 76

Useful vitamin D3, magnesium citrate, boron, and moderate calcium support bone health, but the collagen name is not matched by listed collagen.
How scoring works
$33.75($1.12 per serving)
Vitacost
$ 33.75
Vitacost
$ 33.75
iHerb
$ 33.75
Walmart
$ 33.75
Amazon
$ 33.75
Pure Formulas
$ 33.75
Report prices

Analysis

The serving provides 300 mg calcium, 100 mg magnesium citrate, 25 mcg vitamin D3, and 3 mg boron. Those ingredients give the formula meaningful bone relevance without an unusually large calcium load.

Bamboo extract contributes 5 mg silicon and dried plum extract adds 100 mg polyphenols, but neither ingredient is characterized in enough detail to judge its active yield closely. Despite the product name, no collagen is listed in the supplied ingredients.

Four capsules make a serving, and the bottle lasts 30 days. The product is best viewed as a moderate bone-support formula rather than a collagen or hair supplement.

Who is it for
  • Adults seeking moderate-dose bone support
  • Users who prefer magnesium citrate
  • People who do not want a very high calcium serving
Best for
  • Bone health support
  • Vitamin D3 and boron intake
  • Moderate calcium supplementation

Pros

  • 25 mcg vitamin D3
  • 100 mg magnesium citrate
  • 3 mg boron
  • Moderate 300 mg calcium

Cons

  • Four capsules per serving
  • No collagen appears in the supplied ingredients
  • Bamboo silicon is not standardized
  • Only 30 servings

Warnings

  • The 300 mg calcium serving should be included when reviewing total calcium intake or a kidney-stone prevention plan

Nutrient quality

86 Highest impact

The core amounts provide meaningful support for the intended use. Form quality is mixed or strong, while secondary ingredients add less depth.

Ingredient transparency

82 Highest impact

The listed active ingredients have specific amounts and no proprietary blend hides the core doses. Full use directions and a complete inactive-ingredient list are not supplied.

Customer satisfaction

68 High impact

The aggregate satisfaction signal is strong and the supplied volume is moderate. No specific experience details are supplied to assess repeated complaints or purpose-related outcomes.

Value for money

61 Moderate impact

The core actives provide some quality, but serving value is only modest or weak. Limited targeting, uncertain forms, or a heavy serving reduce competitiveness.

Report analysis

Goals

General Health
General Health
Impact
Highest effect
A- Goal FitA- Strength of SupportB+ CoverageA Formula Quality
Vitamin D · 25 mcgMagnesium · 100 mgBoron · 3 mg

Vitamin D3, calcium, magnesium, silicon, boron, and plum extract form a broad structural-health blend. The combination supports mineral metabolism and bone-related pathways more comprehensively than boron alone.

Calcium fructoborate and magnesium citrate are useful forms, and the key mineral amounts are clearly stated. Magnesium is modest relative to calcium, while the plum and silicon amounts provide less certain depth.

Study evidence
Boron Supportive 6 studies
Magnesium Supportive 114 studies
Vitamin D Supportive 115 studies
Bone Health
Bone Health
Impact
High effect
B+ Goal FitB Strength of SupportB CoverageB+ Formula Quality
Magnesium · 100 mgCalcium · 300 mgVitamin D · 25 mcgBoron · 3 mg

Calcium, magnesium, vitamin D3, boron, silicon, and plum polyphenols provide broad skeletal support. The calcium and magnesium amounts are moderate, while vitamin D3 and boron add meaningful regulatory support.

Despite the product name, no collagen ingredient is listed in the supplied data, so direct protein-matrix support cannot be credited. Magnesium citrate is favorable, while the calcium form and bamboo silicon standardization remain unclear.

Study evidence
Boron Supportive 5 studies
Calcium Supportive 144 studies
Magnesium Supportive 48 studies
Silicon Supportive 13 studies
Vitamin D Supportive 202 studies
Testosterone Support
Testosterone Support
Impact
High effect
B Goal FitB Strength of SupportB- CoverageB- Formula Quality
Magnesium · 100 mgVitamin D · 25 mcgBoron · 3 mg

Vitamin D3, boron, and magnesium provide several relevant foundations for endocrine health. Vitamin D and boron have useful human evidence, while magnesium benefit depends largely on baseline status.

Boron is well dosed, vitamin D is moderate, and magnesium provides a smaller supportive amount. D3, magnesium citrate, and calcium fructoborate are favorable and clearly specified forms.

Study evidence
Boron Disputed 3 studies
Magnesium Disputed 5 studies
Vitamin D Supportive 56 studies
Hair Health
Hair Health
Impact
Moderate effect
C- Goal FitC+ Strength of SupportD CoverageD Formula Quality
Vitamin D · 25 mcg

Silicon may support hair-shaft strength, while vitamin D adds a deficiency-related follicle nutrient. The hair evidence is supportive rather than direct because the formula was built mainly for bone health.

Five milligrams of silicon reaches the preferred range and vitamin D is supplied at a meaningful amount. The silicon amount is clear, but bamboo extract lacks a stated silica percentage or extraction standard.

Study evidence
Silicon Supportive 2 studies
Vitamin D Disputed 34 studies
Nail Health
Nail Health
Impact
Moderate effect
D+ Goal FitC- Strength of SupportD- CoverageF Formula Quality
Silicon · 5 mg

Silicon may support nail hardness and connective-tissue structure, while zinc and vitamin D provide secondary nutritional support only in limited form. The product is designed for bone health, so most of its mineral load does not directly target nails.

The silicon amount is visible but its active yield from bamboo extract is not standardized. Large calcium and magnesium amounts create a bulky serving with limited additional nail benefit.

Study evidence
Calcium Supportive 1 study
Magnesium Not classified

No linked studies yet.

Silicon Supportive 2 studies
Vitamin D Supportive 8 studies

Ingredients

IngredientAmount per serving
Vitamin D3 (Cholecalciferol)
 25 mcg
Calcium
300 mg
Magnesium (Magnesium Citrate)
 100 mg
Silicon (Bamboo extract)
 5 mg
dried Plum extract (Polyphenols)
 100 mg
Boron (Calcium Fructoborate)
 3 mg
Adults 18–50
Report overview
Boron (Calcium Fructoborate) · 3 mg OverallScore70
A- Active Ingredient Quality & BioavailabilityA- Dose, Safety & Label TransparencyF Value

Calcium fructoborate offers a high-quality form at a well-aligned 3 mg serving. The source is not trademarked and the amount is not explicitly identified as elemental boron. Boron-specific value is poor because the product also includes collagen-support and broader bone-health ingredients.

View ingredientView products
Silicon (Bamboo extract) · 5 mg OverallScore59
D+ Active Ingredient Quality & BioavailabilityB+ Dose, Safety & Label TransparencyF Value

Bamboo-derived silicon reaches the preferred elemental dose range and comes from a clearly identified botanical source. No silica percentage, extract ratio, or trademarked source is disclosed, so absorption and extract consistency remain uncertain. The high serving cost weakens value when judged specifically as a silicon supplement.

View ingredientView products
Calcium · 300 mg OverallScore49
F Active Ingredient Quality & BioavailabilityB+ Dose, Safety & Label TransparencyF Value

The undisclosed calcium form prevents a meaningful absorption assessment. The serving amount supports general supplementation rather than high calcium needs on its own; no listed purity concern materially weakens the formulation. The high serving cost limits value.

View ingredientView products
Loading alternative details
83 Performance

Nutra-Support Bone

Carlson
<p>Calcium citrate, magnesium citrate, vitamin D3, chelated zinc and manganese, and boron create broader bone support with well-chosen forms. The four-softgel serving is less convenient, but the mineral quality is more consistent.</p>
81 Performance

Bone Restore with Vitamin K2

Life Extension
<p>Multiple calcium forms, vitamin D3, boron, and a substantial MK-7 addition cover calcium use more completely than the original. Magnesium oxide remains a limitation, and vitamin K requires care with warfarin-type medicines.</p>
84 Performance

Advanced Bone Support

Thorne
<p>Calcium malate, magnesium malate, vitamin D3, and boron give the core bone nutrients stronger disclosed forms. Active vitamin B6 and methylcobalamin add useful cofactors, though vitamin K is absent.</p>
77 Budget

Calcium Magnesium plus Boron

Solgar
<p>Substantial calcium and magnesium plus boron provide a lower-cost mineral-focused alternative. Citrate and gluconate forms are useful, although carbonate and oxide make the blend less consistently absorbable than the original.</p>
77 Budget

Calcium Citrate Magnesium and Zinc

Kirkland Signature
<p>Calcium, vitamin D3, magnesium, zinc, and boron preserve the main bone-support role at a much lower serving cost. Mineral forms are not disclosed, so absorption quality is less certain than with the original magnesium citrate.</p>
85 Budget

BoneUp

Jarrow Formulas
<p>Microcrystalline hydroxyapatite calcium adds vitamin K2 and a broader trace-mineral network while costing less per serving. Magnesium oxide is a weaker form, but the formula covers more calcium-handling pathways than the original.</p>
83 Value

Calcium Bone Maker Complex with MCH-Cal and VitaMK7

Doctor's Best
<p>Hydroxyapatite calcium, magnesium malate, vitamin D3, MK-7, and boron provide broad bone support at favorable value. Its trace-mineral forms are also well chosen, although one zinc unit is unclear in the supplied label data.</p>
76 Value

Bone Strength

NATURELO Premium Supplements
<p>Aquamin calcium and magnesium combine with vitamin D3, MK-7, zinc, boron, and vitamin C for balanced bone coverage. The serving is not the cheapest and the magnesium form is incompletely described, but the broader formula improves value for users wanting vitamin K2.</p>
83 Value

Cal/Mag Citrate

NaturesPlus
<p>Calcium citrate, magnesium citrate, and boron citrate offer clearly disclosed, practical mineral amounts with favorable form quality. The narrower formula omits vitamin D3 and silicon, but it delivers the central minerals more economically.</p>
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Associations of dietary calcium intake with metabolic syndrome and bone mineral density among the Korean population: KNHANES 2008-2011.
    Kim MK; Chon SJ; Noe EB; Roh YH; Yun BH; Cho S; Choi YS; Lee BS; Seo SK · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2018
    Cross-sectional study14,705 participantsBone Health forCalcium
  2. Calcium supplementation during pregnancy and maternal and offspring bone health: a systematic review and meta-analysis.
    Tihtonen K; Korhonen P; Isojärvi J; Ojala R; Ashorn U; Ashorn P; Tammela O · Annals of the New York Academy of Sciences · 2022
    Meta-analysis1,566 participants7 studies pooledBone Health forCalcium
  3. Bone turnover and the response to alendronate treatment in postmenopausal osteoporosis.
    Gonnelli S; Cepollaro C; Pondrelli C; Martini S; Montagnani A; Monaco R; Gennari C · Calcified tissue international · 1999
    Randomized trial100 participantsBone Health forCalcium
  4. [Comparative study of the urinary excretion of boron, calcium, magnesium and phosphorus in postmenopausal women with and without osteoporosis].
    José Ramón V; Mora Mora M; Marino Alarcón O; Hernández G; Josefina Linares L; Urdaneta Romero H; Arévalo González E · Investigacion clinica · 2013
    Case-control study45 participantsBone Health forBoron
  5. Effects of boron supplementation on bone mineral density and dietary, blood, and urinary calcium, phosphorus, magnesium, and boron in female athletes.
    Meacham SL; Taper LJ; Volpe SL · Environmental health perspectives · 1995
    Randomized trial28 participantsBone Health forBoron
  6. Effect of dietary boron on mineral, estrogen, and testosterone metabolism in postmenopausal women.
    Nielsen FH; Hunt CD; Mullen LM; Hunt JR · FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 1987
    Single-arm trial12 participantsBone Health forBoron
  7. The relationship between boron and magnesium status and bone mineral density in the human: a review.
    Volpe SL; Taper LJ; Meacham S · Magnesium research · 1994
    Narrative reviewBone Health forBoron
  8. Metabolic responses of postmenopausal women to supplemental dietary boron and aluminum during usual and low magnesium intake: boron, calcium, and magnesium absorption and retention and blood mineral concentrations
    C D Hunt, J L Herbel, F H Nielsen · The American Journal of Clinical Nutrition · 1997
    Non-randomized trial11 participantsBone Health forBoron
  9. What is the impact of daily oral supplementation of vitamin D3 (cholecalciferol) plus calcium on the incidence of hip fracture in older people? A systematic review and meta-analysis.
    Manoj P; Derwin R; George S · International journal of older people nursing · 2023
    Meta-analysis12,620 participants7 studies pooledBone Health forCalcium
  10. Calcium supplementation prevents seasonal bone loss and changes in biochemical markers of bone turnover in elderly New England women: a randomized placebo-controlled trial.
    Storm D; Eslin R; Porter ES; Musgrave K; Vereault D; Patton C; Kessenich C; Mohan S; Chen T; Holick MF; Rosen CJ · The Journal of clinical endocrinology and metabolism · 1998
    Randomized trial60 participantsBone Health forCalcium
  11. The effects of calcium supplementation (milk powder or tablets) and exercise on bone density in postmenopausal women.
    Prince R; Devine A; Dick I; Criddle A; Kerr D; Kent N; Price R; Randell A · Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 1995
    Randomized trial168 participantsBone Health forCalcium
  12. The efficacy of calcium supplementation alone in elderly Thai women over a 2-year period: a randomized controlled trial.
    Rajatanavin R; Chailurkit L; Saetung S; Thakkinstian A; Nimitphong H · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2014
    Randomized trial404 participantsBone Health forCalcium
  13. Calcium-enriched foods and bone mass growth in prepubertal girls: a randomized, double-blind, placebo-controlled trial.
    Bonjour JP; Carrie AL; Ferrari S; Clavien H; Slosman D; Theintz G; Rizzoli R · The Journal of clinical investigation · 1997
    Randomized trial149 participantsBone Health forCalcium
  14. Association between Serum Magnesium and Fractures: A Systematic Review and Meta-Analysis of Observational Studies.
    Dominguez LJ; Veronese N; Ciriminna S; Pérez-Albela JL; Vásquez-López VF; Rodas-Regalado S; Di Bella G; Parisi A; Tagliaferri F; Barbagallo M · Nutrients · 2023
    Meta-analysis119,755 participants4 studies pooledBone Health forMagnesium
  15. Bioabsorbable Magnesium-Based Materials Potential and Safety in Bone Surgery: A Systematic Review.
    Hung CH; Kwok YC; Yip J; Wong HH; Leung YY · Craniomaxillofacial trauma & reconstruction · 2025
    Systematic review386 participants8 studies pooledBone Health forMagnesium
  16. Vascularized bone grafting fixed by biodegradable magnesium screw for treating osteonecrosis of the femoral head.
    Zhao D; Huang S; Lu F; Wang B; Yang L; Qin L; Yang K; Li Y; Li W; Wang W; Tian S; Zhang X; Gao W; Wang Z; Zhang Y; Xie X; Wang J; Li J · Biomaterials · 2016
    Randomized trial48 participantsBone Health forMagnesium
  17. An update on magnesium and bone health.
    Rondanelli M; Faliva MA; Tartara A; Gasparri C; Perna S; Infantino V; Riva A; Petrangolini G; Peroni G · Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2022
    Narrative reviewBone Health forMagnesium
  18. Sex-specific differences in the association of magnesium intake with femoral neck bone mineral density among older adults.
    Wang B; Tan X; Yao X; Zhu Z · Endocrine connections · 2025
    Cross-sectional study1,343 participantsBone Health forMagnesium
  19. The effect of choline-stabilized orthosilicic acid in patients with peri-implantitis: an exploratory randomized, double-blind, placebo controlled study.
    Teughels W; Celik GU; Tarce M; De Cock I; Persyn SM; Haytac MC · BMC oral health · 2021
    Randomized trial21 participantsBone Health forSilicon
  20. Calcium Phosphate Modified with Silicon vs. Bovine Hydroxyapatite for Alveolar Ridge Preservation: Densitometric Evaluation, Morphological Changes and Histomorphometric Study.
    Cadenas-Vacas G; Martínez-Rodríguez N; Barona-Dorado C; Sánchez-Labrador L; Cortés-Bretón Brinkmann J; Meniz-García C; Martínez-González JM · Materials (Basel, Switzerland) · 2021
    Non-randomized trialBone Health forSilicon
  21. Silicon: a review of its potential role in the prevention and treatment of postmenopausal osteoporosis.
    Price CT; Koval KJ; Langford JR · International journal of endocrinology · 2013
    Narrative reviewBone Health forSilicon
  22. Osteogenic Effect of a Bioactive Calcium Alkali Phosphate Bone Substitute in Humans.
    Knabe C; Adel-Khattab D; Rezk M; Cheng J; Berger G; Gildenhaar R; Wilbig J; Günster J; Rack A; Heiland M; Knauf T; Stiller M · Bioengineering (Basel, Switzerland) · 2023
    Clinical trial38 participantsBone Health forSilicon
  23. Silicon and bone health.
    Jugdaohsingh R · The journal of nutrition, health & aging · 2007
    Narrative reviewBone Health forSilicon
  24. Pregnancy vitamin D supplementation and offspring bone mineral density in childhood follow-up of a randomized controlled trial.
    Moon RJ; D' Angelo S; Curtis EM; Ward KA; Crozier SR; Schoenmakers I; Javaid MK; Bishop NJ; Godfrey KM; Cooper C; Harvey NC; MAVIDOS Trial Group · The American journal of clinical nutrition · 2024
    Randomized trial454 participantsBone Health forVitamin D
  25. Vitamin D analogs and bone: preclinical and clinical studies with eldecalcitol.
    Matsumoto T; Takano T; Saito H; Takahashi F · BoneKEy reports · 2014
    Narrative reviewBone Health forVitamin D
  26. Efficacy of vitamin D fortified foods on bone mineral density and serum bone biomarkers: A systematic review and meta-analysis of interventional studies.
    Tangestani H; Djafarian K; Emamat H; Arabzadegan N; Shab-Bidar S · Critical reviews in food science and nutrition · 2020
    Meta-analysis1,786 participants20 studies pooledBone Health forVitamin D
  27. Cholecalciferol Supplementation Attenuates Bone Loss in Incident Kidney Transplant Recipients: A Prespecified Secondary Endpoint Analysis of a Randomized Controlled Trial.
    Tsujita M; Doi Y; Obi Y; Hamano T; Tomosugi T; Futamura K; Okada M; Hiramitsu T; Goto N; Isaka Y; Takeda A; Narumi S; Watarai Y · Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2022
    Randomized trial193 participantsBone Health forVitamin D
  28. Vitamin D supplementation and bone health in post-menopausal women: a 24-month randomized controlled intervention with enhanced bioavailability formulations.
    Rasool N; Munir Y · European journal of clinical nutrition · 2026
    Randomized trial612 participantsBone Health forVitamin D
  29. Effects of boron supplementation on the severity and duration of pain in primary dysmenorrhea.
    Nikkhah S; Dolatian M; Naghii MR; Zaeri F; Taheri SM · Complementary therapies in clinical practice · 2015
    Randomized trial113 participantsGeneral Health forBoron
  30. Efficacy and safety of tavaborole topical solution, 5%, a novel boron-based antifungal agent, for the treatment of toenail onychomycosis: Results from 2 randomized phase-III studies.
    Elewski BE; Aly R; Baldwin SL; González Soto RF; Rich P; Weisfeld M; Wiltz H; Zane LT; Pollak R · Journal of the American Academy of Dermatology · 2015
    Randomized trialGeneral Health forBoron
  31. The efficacy and safety of tavaborole, a novel, boron-based pharmaceutical agent: phase 2 studies conducted for the topical treatment of toenail onychomycosis.
    Toledo-Bahena ME; Bucko A; Ocampo-Candiani J; Herz-Ruelas ME; Jones TM; Jarratt MT; Pollak RA; Zane LT · Journal of drugs in dermatology : JDD · 2015
    Clinical trial336 participantsGeneral Health forBoron
  32. Boron neutron capture therapy (BNCT) for glioblastoma multiforme: a phase II study evaluating a prolonged high-dose of boronophenylalanine (BPA).
    Henriksson R; Capala J; Michanek A; Lindahl SA; Salford LG; Franzén L; Blomquist E; Westlin JE; Bergenheim AT; Swedish Brain Tumour Study Group · Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology · 2009
    Single-arm trial30 participantsGeneral Health forBoron
  33. Effects of Calcium Fructoborate on Levels of C-Reactive Protein, Total Cholesterol, Low-Density Lipoprotein, Triglycerides, IL-1β, IL-6, and MCP-1: a Double-blind, Placebo-controlled Clinical Study
    Otilia-Constantina Rogoveanu, George Dan Mogosanu, Cornelia Bejenaru, Ludovic Everard Bejenaru, Octavian Croitoru, Johny Neamtu, Zbigniew Pietrzkowski, Tania Reyes-Izquierdo, Andrei Bita, Iulia Daria Scorei, Romulus Ion Scorei · Biological Trace Element Research · 2015
    Randomized trial78 participantsGeneral Health forBoron
  34. Perioperative systemic magnesium to minimize postoperative pain: a meta-analysis of randomized controlled trials.
    De Oliveira GS; Castro-Alves LJ; Khan JH; McCarthy RJ · Anesthesiology · 2013
    Meta-analysis1,257 participants20 studies pooledGeneral Health forMagnesium
  35. Long-term outcome after intravenous magnesium sulphate in suspected acute myocardial infarction: the second Leicester Intravenous Magnesium Intervention Trial (LIMIT-2).
    Woods KL; Fletcher S · Lancet (London, England) · 1994
    Randomized trial2,316 participantsGeneral Health forMagnesium
  36. Association of magnesium sulfate use with mortality in critically ill patients with sepsis: a retrospective propensity score-matched cohort study.
    Gu WJ; Duan XJ; Liu XZ; Cen Y; Tao LY; Lyu J; Yin HY · British journal of anaesthesia · 2023
    Cohort study10,999 participantsGeneral Health forMagnesium
  37. Hypomagnesemia and Mortality in Incident Hemodialysis Patients.
    Li L; Streja E; Rhee CM; Mehrotra R; Soohoo M; Brunelli SM; Kovesdy CP; Kalantar-Zadeh K · American journal of kidney diseases : the official journal of the National Kidney Foundation · 2016
    Cohort study9,359 participantsGeneral Health forMagnesium
  38. The effects of magnesium supplementation on abnormal uterine bleeding, alopecia, quality of life, and acne in women with polycystic ovary syndrome: a randomized clinical trial.
    Jaripur M; Ghasemi-Tehrani H; Askari G; Gholizadeh-Moghaddam M; Clark CCT; Rouhani MH · Reproductive biology and endocrinology : RB&E · 2022
    Randomized trial64 participantsGeneral Health forMagnesium
  39. Vitamin D supplementation for prevention of mortality in adults.
    Bjelakovic G; Gluud LL; Nikolova D; Whitfield K; Wetterslev J; Simonetti RG; Bjelakovic M; Gluud C · The Cochrane database of systematic reviews · 2014
    Meta-analysis95,286 participants159 studies pooledGeneral Health forVitamin D
  40. Effect of vitamin D on gastrointestinal symptoms and health-related quality of life in irritable bowel syndrome patients: a randomized double-blind clinical trial.
    Abbasnezhad A; Amani R; Hajiani E; Alavinejad P; Cheraghian B; Ghadiri A · Neurogastroenterology and motility · 2018
    Randomized trial90 participantsGeneral Health forVitamin D
  41. The impact of vitamin D administration on mortality in COVID-19 patients: a systematic review and meta-analysis of randomized controlled trials.
    Kow CS; Ramachandram DS; Hasan SS; Wong Z; Thiruchelvam K · Inflammopharmacology · 2024
    Meta-analysis2,495 participants19 studies pooledGeneral Health forVitamin D
  42. Vitamin D Status and Mortality: A Systematic Review of Observational Studies.
    Heath AK; Kim IY; Hodge AM; English DR; Muller DC · International journal of environmental research and public health · 2019
    Systematic review84 studies pooledGeneral Health forVitamin D
  43. Meta-analysis of long-term vitamin D supplementation on overall mortality.
    Zheng Y; Zhu J; Zhou M; Cui L; Yao W; Liu Y · PloS one · 2014
    Meta-analysis42 studies pooledGeneral Health forVitamin D
  44. Effect of oral intake of choline-stabilized orthosilicic acid on skin, nails and hair in women with photodamaged skin.
    Barel A; Calomme M; Timchenko A; De Paepe K; Demeester N; Rogiers V; Clarys P; Vanden Berghe D · Archives of dermatological research · 2006
    Randomized trial50 participantsHair Health Nail Health forSilicon
  45. Effect of oral intake of choline-stabilized orthosilicic acid on hair tensile strength and morphology in women with fine hair
    R R Wickett, E Kossmann, A Barel, N Demeester, P Clarys, D Vanden Berghe, M Calomme · Archives of Dermatological Research · 2007
    Randomized trial48 participantsHair Health forSilicon
  46. Increased prevalence of vitamin D deficiency in patients with alopecia areata: a systematic review and meta-analysis.
    Lee S; Kim BJ; Lee CH; Lee WS · Journal of the European Academy of Dermatology and Venereology : JEADV · 2018
    Meta-analysis2,039 participants14 studies pooledHair Health forVitamin D
  47. Intralesional vitamin D3 in treatment of alopecia areata: A randomized controlled clinical trial.
    Rashad AF; Elgamal E; Fouda I · Journal of cosmetic dermatology · 2022
    Randomized trial60 participantsHair Health forVitamin D
  48. Vitamin D and its Analogs in Treatment of Mild to Moderate Alopecia Areata: Systematic Review and Meta-Analysis.
    Alsaati AA; Kaliyadan F; Alsaadoun D; Alzakry LM; Alzabadin RA; Hakami TH; Rubaian NFB · Indian dermatology online journal · 2025
    Meta-analysisHair Health forVitamin D
  49. Topical calcipotriol vs narrowband ultraviolet B in treatment of alopecia areata: a randomized-controlled trial.
    El Taieb MA; Hegazy EM; Ibrahim HM; Osman AB; Abualhamd M · Archives of dermatological research · 2020
    Randomized trial60 participantsHair Health forVitamin D
  50. Serum 25 hydroxyvitamin D in non-scarring alopecia: A systematic review and meta-analysis.
    Chen Y; Dong X; Wang Y; Li Y; Xiong L; Li L · Journal of cosmetic dermatology · 2024
    Meta-analysis10,670 participants23 studies pooledHair Health forVitamin D
  51. Predictive Model of Nail Consistency Using Scanning Electron Microscopy with Energy-Dispersive X-Ray.
    Mingorance Álvarez E; Martínez Quintana R; Pérez Pico AM; Mayordomo R · Biology · 2021
    Cross-sectional study57 participantsNail Health forCalcium
  52. Nail Supplements: When, How, and Why?
    Zaraa I; Richert B · Skin appendage disorders · 2026
    Narrative reviewNail Health forSilicon
  53. Recommendations for the definition, evaluation, and treatment of nail psoriasis in adult patients with no or mild skin psoriasis: A dermatologist and nail expert group consensus.
    Rigopoulos D; Baran R; Chiheb S; Daniel CR; Di Chiacchio N; Gregoriou S; Grover C; Haneke E; Iorizzo M; Pasch M; Piraccini BM; Rich P; Richert B; Rompoti N; Rubin AI; Singal A; Starace M; Tosti A; Triantafyllopoulou I; Zaiac M · Journal of the American Academy of Dermatology · 2019
    Guideline / consensusNail Health forVitamin D
  54. Vitamins for the Management of Nail Disease: A Literature Review.
    Curtis KL; Lipner SR · Skin appendage disorders · 2025
    Narrative reviewNail Health forVitamin D
  55. Nail involvement in psoriatic arthritis.
    Sobolewski P; Walecka I; Dopytalska K · Reumatologia · 2019
    Narrative reviewNail Health forVitamin D
  56. Psoriasis treatment in difficult locations: scalp, nails, and intertriginous areas.
    Wozel G · Clinics in dermatology · 2009
    Narrative reviewNail Health forVitamin D
  57. Nail psoriasis: clinical presentation and best practice recommendations.
    Edwards F; de Berker D · Drugs · 2010
    Narrative reviewNail Health forVitamin D
  58. Biochemical and physiologic consequences of boron deprivation in humans.
    Nielsen FH · Environmental health perspectives · 1995
    Single-arm trial12 participantsTestosterone Support forBoron
  59. Plasma boron and the effects of boron supplementation in males.
    Green NR; Ferrando AA · Environmental health perspectives · 1995
    Randomized trial19 participantsTestosterone Support forBoron
  60. Comparative effects of daily and weekly boron supplementation on plasma steroid hormones and proinflammatory cytokines
    Mohammad Reza Naghii, Mahmoud Mofid, Ali Reza Asgari, Mehdi Hedayati, Maryam-Saddat Daneshpour · Journal of Trace Elements in Medicine and Biology · 2011
    Non-randomized trial8 participantsTestosterone Support forBoron
  61. Magnesium and anabolic hormones in older men.
    Maggio M; Ceda GP; Lauretani F; Cattabiani C; Avantaggiato E; Morganti S; Ablondi F; Bandinelli S; Dominguez LJ; Barbagallo M; Paolisso G; Semba RD; Ferrucci L · International journal of andrology · 2012
    Cohort study399 participantsTestosterone Support forMagnesium
  62. Analysis of the relationship between the blood concentration of several metals, macro- and micronutrients and endocrine disorders associated with male aging.
    Rotter I; Kosik-Bogacka DI; Dołęgowska B; Safranow K; Kuczyńska M; Laszczyńska M · Environmental geochemistry and health · 2017
    Cross-sectional study313 participantsTestosterone Support forMagnesium
  63. Effect of magnesium supplementation in improving hyperandrogenism, hirsutism, and sleep quality in women with polycystic ovary syndrome: A randomized, placebo-controlled clinical trial.
    Gholizadeh-Moghaddam M; Ghasemi-Tehrani H; Askari G; Jaripur M; Clark CCT; Rouhani MH · Health science reports · 2024
    Randomized trial64 participantsTestosterone Support forMagnesium
  64. The effects of trace element supplementation on glycolipid metabolism in PCOS: a systematic review and meta-analysis.
    Yang L; Gao Y; Zhao W; Qi Y; Duo X; Wang H · Frontiers in nutrition · 2025
    Meta-analysis1,600 participants25 studies pooledTestosterone Support forMagnesium
  65. Effects of magnesium supplementation on testosterone levels of athletes and sedentary subjects at rest and after exhaustion.
    Cinar V; Polat Y; Baltaci AK; Mogulkoc R · Biological trace element research · 2011
    Non-randomized trial20 participantsTestosterone Support forMagnesium
  66. Effect of Two Different Doses of Vitamin D Supplementation on Metabolic Profiles of Insulin-Resistant Patients with Polycystic Ovary Syndrome.
    Jamilian M; Foroozanfard F; Rahmani E; Talebi M; Bahmani F; Asemi Z · Nutrients · 2018
    Randomized trial90 participantsTestosterone Support forVitamin D
  67. Androgens and hirsutism score of overweight women with polycystic ovary syndrome improved after vitamin D treatment: A randomized placebo controlled clinical trial.
    Al-Bayyari N; Al-Domi H; Zayed F; Hailat R; Eaton A · Clinical nutrition (Edinburgh, Scotland) · 2021
    Randomized trial60 participantsTestosterone Support forVitamin D
  68. Association between plasma 25-OH vitamin D and testosterone levels in men.
    Nimptsch K; Platz EA; Willett WC; Giovannucci E · Clinical endocrinology · 2012
    Case-control study1,362 participantsTestosterone Support forVitamin D
  69. Causal Link Between Vitamin D and Total Testosterone in Men: A Mendelian Randomization Analysis.
    Chen C; Zhai H; Cheng J; Weng P; Chen Y; Li Q; Wang C; Xia F; Wang N; Lu Y · The Journal of clinical endocrinology and metabolism · 2020
    Other4,254 participantsTestosterone Support forVitamin D
  70. Associations of vitamin D status and vitamin D-related polymorphisms with sex hormones in older men.
    Rafiq R; van Schoor NM; Sohl E; Zillikens MC; Oosterwerff MM; Schaap L; Lips P; de Jongh RT · The Journal of steroid biochemistry and molecular biology · 2017
    Cohort study643 participantsTestosterone Support forVitamin D