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Mitochondrial Energy Optimizer with PQQ

Life Extension

4.5
(2111 ratings)
Vitamin B6 100 mg
Thiamin 150 mg
Carnosine 1000 mg
Taurine 800 mg
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Score 93.0

This Life Extension supplement is a powerful blend targeting mitochondrial health, energy production, and cellular protection through key ingredients like PQQ, R-Lipoic Acid, Benfotiamine, Carnosine, and Taurine. It aims to support overall vitality, brain function, and cardiovascular health with high-quality, bioavailable forms of nutrients.

Quantity: 120 Capsule(s)Servings size: 2 Vegetarian Capsule(s) (60 servings)
Selected goals:
Other goals:
Energy
Brain Health
Mood Support
General Health
Cognitive Support

Score 93.0

This Life Extension supplement is a powerful blend targeting mitochondrial health, energy production, and cellular protection through key ingredients like PQQ, R-Lipoic Acid, Benfotiamine, Carnosine, and Taurine. It aims to support overall vitality, brain function, and cardiovascular health with high-quality, bioavailable forms of nutrients.

Analysis

Life Extension's Mitochondrial Energy Optimizer with PQQ is designed to enhance cellular energy production and protect cells from oxidative stress, addressing a wide array of health goals. It features a synergistic combination of ingredients, including PQQ for mitochondrial biogenesis, R-Lipoic Acid (Na-RALA) and Benfotiamine for metabolic and antioxidant support, and Carnosine and Taurine for cellular protection and physiological balance. The use of active B6 (Pyridoxal 5-Phosphate) further boosts its efficacy in supporting nervous system health and energy metabolism. This product stands out due to its targeted blend of premium ingredients, which are generally well-regarded in the scientific and nutritional communities for their roles in mitochondrial function and overall vitality, making it a comprehensive choice for those seeking advanced cellular support.

Pros
  • Contains PQQ, a novel compound shown to promote mitochondrial biogenesis, which is crucial for cellular energy and anti-aging processes.
  • Utilizes highly bioavailable and effective forms of nutrients, such as Na-RALA (R-Lipoic Acid) and Pyridoxal 5-Phosphate (active B6), ensuring better absorption and utilization by the body.
  • Offers a comprehensive approach to mitochondrial health with synergistic ingredients that work together to enhance energy production, provide robust antioxidant defense, and support cellular longevity.
  • The doses of key ingredients like Carnosine (1000mg) and L-Taurine (800mg) are substantial and clinically relevant, contributing effectively to their beneficial physiological effects.
Cons
  • The claim for 'Testosterone Support' is not directly or strongly supported by the listed ingredients; while overall health benefits may indirectly support hormone balance, these specific ingredients are not primary testosterone boosters.
  • The specialized nature and inclusion of premium ingredients contribute to a higher price point per serving compared to basic single-nutrient supplements, which might not be suitable for all consumer budgets.
Warnings
  • Individuals with specific medical conditions, especially those affecting blood sugar regulation (due to R-Lipoic Acid and Benfotiamine), or those taking other medications should consult a healthcare professional before use to avoid potential interactions.
  • Although generally well-tolerated, some individuals may experience mild gastrointestinal upset or other sensitivities to high doses of B vitamins or alpha-lipoic acid.
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$48.75($0.81 per serving)
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Effectiveness for goals

Dosage, timing & forms

Safety & interactions

Ingredients

IngredientAmount per serving
Vitamin B6 (Pyridoxal 5-Phosphate) 100 mg
Sodium 18 mg
Carnosine 1000 mg
L-Taurine 800 mg
Benfotiamine 150 mg
R-Lipoic Acid (Na-RALA Sodium R-Lipoate) 150 mg
PQQ (Pyrroloquinoline Quinone) Disodium Salt 10 mg
Gluten Free Adults 18–50
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Categories

The product features Benfotiamine, which is a highly bioavailable, fat-soluble form of Vitamin B1, offering superior absorption and efficacy, especially for nerve and metabolic support, compared to conventional thiamine forms.
It contains Pyridoxal 5-Phosphate (P-5-P), the active coenzyme form of Vitamin B6, ensuring direct utilization by the body for critical metabolic and neurological functions without requiring liver conversion.
With a substantial dose of 1000mg, the product provides effective levels of Carnosine, known for its powerful antioxidant, anti-glycation, and cellular protective properties relevant to longevity and muscle health.

Goals

PQQ, R-Lipoic Acid, and Benfotiamine are directly involved in mitochondrial function and cellular energy production pathways, providing foundational support for sustained energy levels. Taurine also plays a role in energy metabolism.
PQQ's role in mitochondrial biogenesis and the potent antioxidant and anti-glycation properties of R-Lipoic Acid, Benfotiamine, and Carnosine directly support cellular repair, longevity, and defense against age-related damage.
Ingredients such as PQQ and R-Lipoic Acid are neuroprotective, while Benfotiamine supports nerve health and P-5-P B6 is vital for neurotransmitter synthesis, collectively enhancing overall brain health and function.
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This product from the same brand offers a significantly higher dose of Benfotiamine (600mg vs 150mg), directly enhancing its benefits for metabolic health, nerve support, and anti-glycation effects, which aligns with several goals of the original product. Although marketed for liver, Benfotiamine's core actions make it a potent alternative for energy and cellular protection.
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Two-Per-Day Capsules

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From the same reputable brand, this comprehensive multivitamin offers a broad spectrum of essential vitamins and minerals, including high doses of B vitamins (75mg B1, 75mg B6), to holistically support energy, brain, cardiovascular, and general health. It covers many of the original product's goals in a more complete manner at a much lower price per serving.
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B-Complex '100'

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(15200 ratings)
This Solgar B-Complex '100' provides high potencies of multiple B vitamins, including 100mg of both B1 and B6, which are foundational for energy production, brain health, and metabolism. While it doesn't contain Benfotiamine or Carnosine, its comprehensive B-vitamin profile from a trusted brand offers strong support for the core energy and brain goals at a more accessible price point.
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