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Vitamins Only

Solgar
4.7
★ ★ ★ ★ ★
(782 ratings)
Niacin 50 mg
Vitamin B6 50 mg
Thiamin 50 mg
Riboflavin 50 mg
Choline 21 mg
Product Image
Score78
Broad vitamin coverage supports everyday metabolic nutrition, but ordinary forms and high-dose B6 are important long-term trade-offs.
How scoring works
Quantity:90 Capsule(s) • (90 servings)
Goals:
Metabolism Boost
Energy

Score 78

Broad vitamin coverage supports everyday metabolic nutrition, but ordinary forms and high-dose B6 are important long-term trade-offs.
How scoring works
$19.92($0.22 per serving)
Walmart
$ 20.99
Daily Vita
$ 20.99
Vitacost
$ 21.19
Amazon
$ 20.99
iHerb
$ 19.92
Pure Formulas
$ 20.99
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Analysis

The multi-vitamin formula provides several B vitamins at amounts that can support energy metabolism. Its broader vitamin coverage makes it more versatile than a narrow B complex.

Many ingredients use conventional forms without a clear absorption advantage. Choline is present but not at a strong standalone amount, so it should be viewed as supporting rather than central.

The capsule offers a practical option for people who want vitamins without minerals. Vitamin B6 at 50 mg is aggressive for routine use and is the clearest reason to review total daily intake.

Who is it for
  • Adults seeking a vitamin-only formula
  • People wanting broad B-vitamin support
Best for
  • Foundational vitamin coverage
  • Nutritional support for energy metabolism

Pros

  • Broad vitamin profile
  • Meaningful B-vitamin amounts
  • Convenient capsule format

Cons

  • Several standard nutrient forms
  • Choline is modest for targeted use
  • Does not provide mineral coverage

Warnings

  • Vitamin B6 at 50 mg may cause nerve symptoms with prolonged daily intake
  • Combining it with another B complex can raise B6 exposure further

Nutrient quality

79 High impact

Natural vitamin E, cholecalciferol, beta-carotene, and choline bitartrate are useful forms, though several B vitamins remain conventional. Most vitamins have meaningful amounts, while choline is modest and the pantothenic-acid entry appears negligible or unclear.

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Ingredient transparency

81 Highest impact

Most active vitamins have specific amounts, though the pantothenic-acid unit appears questionable. A complete inactive ingredient list was not supplied.

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Customer satisfaction

68 High impact

The available aggregate rating is reasonably strong for this category. No firsthand outcome details were supplied, so alignment with the intended use is uncertain.

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Value for money

82 Highest impact

Broad vitamin coverage and several useful forms provide reasonable quality for the serving cost. The product is reasonably competitive among broad vitamin formulas.

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Goals

Metabolism Boost
Metabolism Boost
Impact
Highest effect
A- Goal FitB+ Strength of SupportB+ CoverageB Formula Quality
Biotin · 50 mcgNiacin · 50 mgVitamin B12 · 50 mcgRiboflavin · 50 mgThiamin · 50 mgVitamin B5 · 50 mcgVitamin B6 · 50 mgVitamin D · 10 mcg

The broad B-vitamin profile is well aligned with converting carbohydrates, fats, and protein into cellular energy. High-potency thiamin, riboflavin, niacin, and vitamin B6 provide substantial cofactor support.

Several ingredients use standard forms rather than their active coenzyme forms, and the riboflavin form is not identified. The wide formula remains coherent, though very small carotenoid amounts add little to the metabolic purpose.

Study evidence
Niacin Supportive 17 studies
Riboflavin Mixed 5 studies
Thiamin Supportive 11 studies
Vitamin B6 Supportive 16 studies
Energy
Energy
Impact
High effect
A- Goal FitB Strength of SupportB- CoverageB Formula Quality
Vitamin D · 10 mcgVitamin B5 · 50 mcgRiboflavin · 50 mgThiamin · 50 mgVitamin B12 · 50 mcg

High thiamine and riboflavin amounts directly support carbohydrate use and mitochondrial energy metabolism. The broader vitamin profile can help prevent several deficiency-related causes of fatigue.

Riboflavin and B12 forms are not fully specified, while many tiny carotenoid entries add little to energy support. The vitamin B6 amount is high enough that long-term daily use may contribute to nerve symptoms in susceptible users.

Study evidence
Riboflavin Mixed 6 studies
Thiamin Disputed 12 studies

Ingredients

IngredientAmount per serving
Vitamin A (Beta-Carotene, Vitamin A Palmitate)
 1531 mcg
Vitamin C (L-Ascorbic Acid)
 250 mg
Vitamin D (Cholecalciferol)
 10 mcg
Vitamin E (D-Alpha-Tocopheryl Acid Succinate)
 100 mg
Thiamine (Thiamine Mononitrate)
 50 mg
Riboflavin
50 mg
Niacin (Niacinamide)
 50 mg
Vitamin B6 (Pyridoxine Hydrochloride)
 50 mg
Folate
666 mcg DFE
Vitamin B12 (Cobalamin)
 50 mcg
Biotin
50 mcg
Pantothenic Acid (D-Calcium Pantothenate)
 50 mcg
Choline (Choline Bitartrate)
 21 mg
Inositol
50 mg
Mixed Carotenoids (Beta-Carotene, Cryptoxanthin, Lutein, Zeaxanthin, Alpha-Carotene)
 29 mcg
Gluten Free Adults 18–50 Kosher Dairy Free Sugar Free
Report overview
Niacin (Niacinamide) · 50 mg OverallScore84
B+ Active Ingredient Quality & BioavailabilityA- Dose, Safety & Label TransparencyB+ Value

The 50 mg niacinamide dose fits a general multivitamin role and should not cause the typical nicotinic-acid flush. Its broad vitamin profile adds practical value, but niacinamide is not the preferred form for lipid-focused use. The ordinary capsule has no stated release feature, and the supplied label details do not call it no-flush.

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Vitamin B6 (Pyridoxine Hydrochloride) · 50 mg OverallScore82
C- Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyA+ Value

The B6 uses pyridoxine hydrochloride, while included riboflavin may help convert it to the active form. Its 50 mg dose is within the preferred range and the broad vitamin formula comes in one capsule. The low serving cost is favorable, but excipient purity cannot be confirmed from the supplied data.

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Thiamin (Thiamine Mononitrate) · 50 mg OverallScore76
B- Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyD- Value

Thiamine mononitrate reaches the lower edge of the preferred high-potency range and is clearly labeled. The multi-vitamin formula offers broad nutrient coverage but is less focused on thiamine alone. Its cost per active thiamine amount is comparatively high for a standard form.

View ingredientView products
Loading alternative details
79 Performance

B Complex Plus

Seeking Health
<p>Active riboflavin, vitamin B6, and vitamin B12 forms create a well-designed B-complex with meaningful amounts. Its ingredient forms and goal coverage compare favorably because the original already supplies substantial vitamin B6, although its concentrated doses are more appropriate for deliberate use than casual stacking.</p>
80 Performance

B-Complex '100'

Solgar
<p>A broad high-potency B-vitamin profile supports normal energy metabolism, but most forms are conventional and several amounts greatly exceed routine needs. Its ingredient forms and goal coverage compare favorably because the original already supplies substantial vitamin B6, although the high pyridoxine amount is less suitable for long-term daily use.</p>
80 Performance

B-100 Complex with B2 Coenzyme

Nature's Way
<p>Active riboflavin and partial P-5-P improve this otherwise conventional high-potency B-complex. Its ingredient forms and goal coverage compare favorably because the original already supplies substantial vitamin B6, although the high pyridoxine amount is less suitable for long-term daily use.</p>
77 Budget

B-50

NOW
<p>A large supply offers broad B-vitamin dosing at excellent serving value. Its lower serving cost improves value compared with the original, although the high pyridoxine amount is less suitable for long-term daily use.</p>
78 Budget

B-50 Complex

21st Century
<p>A budget B-complex provides substantial core B-vitamin amounts with clear active disclosure and a long supply. Its lower serving cost improves value compared with the original, although the high pyridoxine amount is less suitable for long-term daily use.</p>
74 Budget

B-Complex '50'

Solgar
<p>Broad B-vitamin coverage fits energy metabolism, but the formula relies on conventional forms and an unnecessarily high vitamin B6 amount. Its lower serving cost improves value compared with the original, although the high pyridoxine amount is less suitable for long-term daily use.</p>
76 Value

Megasorb B-Complex '50'

Solgar
<p>Active riboflavin and vitamin B6 forms improve a broad B-complex base, but the dose profile is unnecessarily aggressive. The balance of ingredient quality, goal fit, and serving cost is favorable versus the original, although the high pyridoxine amount is less suitable for long-term daily use.</p>
77 Value

B-50 Complex

Nature's Way
<p>Active riboflavin improves a broad and clearly dosed B-complex base, but the vitamin B6 amount is unnecessarily high. The balance of ingredient quality, goal fit, and serving cost is favorable versus the original, although the high pyridoxine amount is less suitable for long-term daily use.</p>
75 Value

B-Complex 50

Bluebonnet
<p>A complete B-vitamin pattern provides focused energy-metabolism support at reasonable serving value. The balance of ingredient quality, goal fit, and serving cost is favorable versus the original, although the high pyridoxine amount is less suitable for long-term daily use.</p>
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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Physicochemical properties of and volatile compounds in riboflavin fortified cloudy apple juice; study of its effect on job fatigue among Egyptian construction workers.
    Fouad S; Ibrahim GE; Hussein AMS; Ibrahim FA; El Gendy A · Heliyon · 2021
    Non-randomized trialEnergy forRiboflavin
  2. Vitamin B status in patients with chronic fatigue syndrome.
    Heap LC; Peters TJ; Wessely S · Journal of the Royal Society of Medicine · 1999
    Case-control study30 participantsEnergy forRiboflavin
  3. B-vitamins, related vitamers, and metabolites in patients with quiescent inflammatory bowel disease and chronic fatigue treated with high dose oral thiamine.
    Bager P; Hvas CL; Hansen MM; Ueland P; Dahlerup JF · Molecular medicine (Cambridge, Mass.) · 2023
    Observational studyEnergy forRiboflavin
  4. Metabolic features of chronic fatigue syndrome.
    Naviaux RK; Naviaux JC; Li K; Bright AT; Alaynick WA; Wang L; Baxter A; Nathan N; Anderson W; Gordon E · Proceedings of the National Academy of Sciences of the United States of America · 2024
    Case-control study84 participantsEnergy forRiboflavin
  5. Effectiveness of Riboflavin in Inherited Metabolic Diseases: A Systematic Review
    Bregje Jaeger, Nina N Stolwijk, Femke Aaldering, Charlotte A Ruys, Marije Smits, Nicole I Wolf, Carla E M Hollak, Annet M Bosch · Journal of Inherited Metabolic Disease · 2026
    Systematic review381 studies pooledEnergy Metabolism Boost forRiboflavin
  6. Influence of thiamin supplementation on the health and general well-being of an elderly Irish population with marginal thiamin deficiency.
    Smidt LJ; Cremin FM; Grivetti LE; Clifford AJ · Journal of gerontology · 1991
    Randomized trial80 participantsEnergy forThiamin
  7. Randomised clinical trial: high-dose oral thiamine versus placebo for chronic fatigue in patients with quiescent inflammatory bowel disease.
    Bager P; Hvas CL; Rud CL; Dahlerup JF · Alimentary pharmacology & therapeutics · 2021
    Randomized trial40 participantsEnergy forThiamin
  8. Dietary reference values for thiamin.
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA); Turck D; Bresson JL; Burlingame B; Dean T; Fairweather-Tait S; Heinonen M; Hirsch-Ernst KI; Mangelsdorf I; McArdle HJ; Naska A; Nowicka G; Pentieva K; Sanz Y; Siani A; Sjödin A; Stern M; Tomé D; Van Loveren H; Vinceti M; Willatts P; Lamberg-Allardt C; Przyrembel H; Tetens I; Gudelj Rakic J; Ioannidou S; de Sesmaisons-Lecarré A; Forss AC; Neuhäuser-Berthold M · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusEnergy forThiamin
  9. Effects of thiamine supplementation on exercise-induced fatigue.
    Suzuki M; Itokawa Y · Metabolic brain disease · 1996
    Randomized trial16 participantsEnergy forThiamin
  10. Long-term maintenance treatment with 300 mg thiamine for fatigue in patients with inflammatory bowel disease: results from an open-label extension of the TARIF study.
    Bager P; Hvas CL; Rud CL; Dahlerup JF · Scandinavian journal of gastroenterology · 2022
    Randomized trialEnergy forThiamin
  11. Niacin and contribution to normal energy-yielding metabolism: evaluation of a health claim pursuant to Article 14 of Regulation (EC) No 1924/2006.
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusMetabolism Boost forNiacin
  12. Targeted Microbiome Intervention by Microencapsulated Delayed-Release Niacin Beneficially Affects Insulin Sensitivity in Humans.
    Fangmann D; Theismann EM; Türk K; Schulte DM; Relling I; Hartmann K; Keppler JK; Knipp JR; Rehman A; Heinsen FA; Franke A; Lenk L; Freitag-Wolf S; Appel E; Gorb S; Brenner C; Seegert D; Waetzig GH; Rosenstiel P; Schreiber S; Schwarz K; Laudes M · Diabetes care · 2018
    Clinical trialMetabolism Boost forNiacin
  13. The differential impact of three different NAD+ boosters on circulatory NAD and microbial metabolism in humans.
    Christen S; Redeuil K; Goulet L; Giner MP; Breton I; Rota R; Frézal A; Nazari A; Van den Abbeele P; Godin JP; Nutten S; Cuenoud B · Nature metabolism · 2026
    Randomized trial65 participantsMetabolism Boost forNiacin
  14. Effects of extended-release niacin on lipid profile and adipocyte biology in patients with impaired glucose tolerance.
    Linke A; Sonnabend M; Fasshauer M; Höllriegel R; Schuler G; Niebauer J; Stumvoll M; Blüher M · Atherosclerosis · 2009
    Randomized trial30 participantsMetabolism Boost forNiacin
  15. Effect of the antilipolytic nicotinic acid analogue acipimox on whole-body and skeletal muscle glucose metabolism in patients with non-insulin-dependent diabetes mellitus.
    Vaag A; Skött P; Damsbo P; Gall MA; Richter EA; Beck-Nielsen H · The Journal of clinical investigation · 1991
    Clinical trial12 participantsMetabolism Boost forNiacin
  16. Disorders of flavin adenine dinucleotide metabolism: MADD and related deficiencies.
    Mereis M; Wanders RJA; Schoonen M; Dercksen M; Smuts I; van der Westhuizen FH · The international journal of biochemistry & cell biology · 2024
    Systematic reviewMetabolism Boost forRiboflavin
  17. Anaemia during pregnancy: could riboflavin deficiency be implicated?
    Duffy B; McNulty H; Ward M; Pentieva K · The Proceedings of the Nutrition Society · 2026
    Narrative reviewMetabolism Boost forRiboflavin
  18. Effects of riboflavin and folic acid supplementation on plasma homocysteine levels in healthy subjects.
    Chuang CZ; Boyles A; Legardeur B; Su J; Japa S; Lopez-S A · The American journal of the medical sciences · 2006
    Non-randomized trial34 participantsMetabolism Boost forRiboflavin
  19. Riboflavin and riboflavin-derived cofactors in adolescent girls with anorexia nervosa.
    Capo-chichi CD; Guéant JL; Lefebvre E; Bennani N; Lorentz E; Vidailhet C; Vidailhet M · The American journal of clinical nutrition · 1999
    Clinical trial34 participantsMetabolism Boost forRiboflavin
  20. Neurological, Psychiatric, and Biochemical Aspects of Thiamine Deficiency in Children and Adults.
    Dhir S; Tarasenko M; Napoli E; Giulivi C · Frontiers in psychiatry · 2026
    Narrative reviewMetabolism Boost forThiamin
  21. Plasma vitamin profiles and their associations with metabolic health and mental wellbeing in midlife Asian women.
    Tan KML; Tint MT; Cabral RM; Lau R; Kee MZL; Garg V; De Iorio M; Tan SSL; Eriksson JG · Scientific reports · 2026
    Cohort study662 participantsMetabolism Boost forThiamin
  22. High-resolution plasma metabolomics and thiamine status in critically Ill adult patients.
    Gundogan K; Nellis MM; Ozer NT; Ergul SS; Sahin GG; Temel S; Yuksel RC; Teeny S; Alvarez JA; Sungur M; Jones DP; Ziegler TR · Metabolomics : Official journal of the Metabolomic Society · 2024
    Cross-sectional study76 participantsMetabolism Boost forThiamin
  23. Pathophysiology, prevention, and treatment of beriberi after gastric surgery.
    Wilson RB · Nutrition reviews · 2021
    Narrative reviewMetabolism Boost forThiamin
  24. Red blood cell transketolase activity and the effect of thiamine supplementation in patients with chronic liver disease.
    Rossouw JE; Labadarios D; Krasner N; Davis M; Williams R · Scandinavian journal of gastroenterology · 1978
    Single-arm trialMetabolism Boost forThiamin
  25. Plasma vitamin B6 vitamers before and after oral vitamin B6 treatment: a randomized placebo-controlled study.
    Bor MV; Refsum H; Bisp MR; Bleie Ø; Schneede J; Nordrehaug JE; Ueland PM; Nygard OK; Nexø E · Clinical chemistry · 2003
    Randomized trial90 participantsMetabolism Boost forVitamin B6
  26. Dietary one-carbon metabolism nutrients and risk of MASLD progression: a prospective cohort study.
    Shen L; Wang K; Li R; Li Y; Guo Y; Li F; Yuan J; Yang Z; Xia B; Lin X · European journal of clinical nutrition · 2026
    Cohort study46,800 participantsMetabolism Boost forVitamin B6
  27. Associations of Vitamin B6 Intake and Plasma Pyridoxal 5'-Phosphate with Plasma Polyunsaturated Fatty Acids in US Older Adults: Findings from NHANES 2003-2004.
    Kim H; Enrione EB; Narayanan V; Li T; Campa A · Nutrients · 2022
    Cross-sectional study461 participantsMetabolism Boost forVitamin B6
  28. Influence of oral contraceptives, pyridoxine (vitamin B6), and tryptophan on carbohydrate metabolism.
    Adams PW; Wynn V; Folkard J; Seed M · Lancet (London, England) · 1976
    Clinical trial46 participantsMetabolism Boost forVitamin B6
  29. Effect of oral contraceptives and vitamin B6 deficiency on carbohydrate metabolism.
    Rose DP; Leklem JE; Brown RR; Linkswiler HM · The American journal of clinical nutrition · 1975
    Clinical trialMetabolism Boost forVitamin B6