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Super Kidney Cleanse

Health Plus
4.6
★ ★ ★ ★ ★
(1531 ratings)
Riboflavin 30 mg
Vitamin B6 37 mg
Thiamin 25 mg
Copper 0.8 mg
Vitamin B12 525 mcg
Vitamin K 210 mcg
Stinging Nettle 40 mg
Product Image
Score62
The formula combines high-potency B vitamins, magnesium citrate, vitamin K1, and a modest urinary-herb blend, but it is not a balanced kidney or general-health supplement. Uva ursi is not suited to prolonged routine use, the diuretic herbs may be risky with kidney disease or fluid-balance medicines, and vitamin K1 can interfere with warfarin control.
How scoring works
Quantity:90 Capsule(s) • (45 servings)
Goals:
Energy
General Health

Score 62

The formula combines high-potency B vitamins, magnesium citrate, vitamin K1, and a modest urinary-herb blend, but it is not a balanced kidney or general-health supplement. Uva ursi is not suited to prolonged routine use, the diuretic herbs may be risky with kidney disease or fluid-balance medicines, and vitamin K1 can interfere with warfarin control.
How scoring works
$21.29($0.47 per serving)
iHerb
$ 21.29
Amazon
$ 21.29
Pure Formulas
$ 21.29
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Analysis

The formula combines high-potency B vitamins, magnesium citrate, vitamin K1, and a modest urinary-herb blend, but it is not a balanced kidney or general-health supplement. Uva ursi is not suited to prolonged routine use, the diuretic herbs may be risky with kidney disease or fluid-balance medicines, and vitamin K1 can interfere with warfarin control.

Pyridoxine hydrochloride is less direct than active P-5-P, though riboflavin may support its conversion. The 37 mg dose fits the preferred range and is clearly delivered in two capsules.

Vitamin B12 reaches a targeted amount, while thiamine, riboflavin, and vitamin B6 support metabolic energy production. Magnesium citrate adds modest support for ATP-dependent reactions.

Who is it for
  • Adults focused on energy
  • Adults focused on general health
  • Adults focused on anti-aging
Best for
  • Vitamin B6 supplementation
  • Riboflavin supplementation
  • Thiamin supplementation

Pros

  • Provides a disclosed 210.00mcg of vitamin k1
  • Provides a disclosed 75.00mg of magnesium
  • Provides a disclosed 40.00mg of uva ursi leaf extract

Cons

  • Uva ursi is not suited to prolonged routine use
  • Several herbs may increase fluid loss
  • The formula is not a balanced kidney-support product

Warnings

  • Uva ursi is not suited to prolonged routine use and may be especially inappropriate with kidney disease.
  • Dandelion, parsley, and related diuretic herbs may worsen dehydration or interact with diuretic and fluid-balance medicines.
  • Vitamin K1 can oppose warfarin and related medicines, so intake should remain consistent and medically coordinated.

Nutrient quality

50 Moderate impact

Magnesium citrate is a useful form, while the B vitamins and most herbal extracts use basic or unspecified forms. Several vitamins are substantial, but the kidney-cleanse herbs are modest and not well standardized.

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Ingredient transparency

77 High impact

Active amounts are disclosed, but most herbal extracts lack standardization details. Complete non-active ingredient details are not included in the supplied label data.

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Customer satisfaction

70 High impact

The supplied average rating provides limited high-level context. Detailed firsthand feedback is unavailable, so recurring complaints and purpose fit cannot be assessed.

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Value for money

46 Lower impact

The moderate serving cost buys broad ingredients but mixed form and evidence quality. Several lightly dosed botanicals limit effective serving value.

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Report analysis

Goals

Energy
Energy
Impact
Moderate effect
D+ Goal FitC+ Strength of SupportD+ CoverageD+ Formula Quality
Magnesium · 75 mgRiboflavin · 30 mgThiamin · 25 mgVitamin B12 · 525 mcg

Vitamin B12 reaches a targeted amount, while thiamine, riboflavin, and vitamin B6 support metabolic energy production. Magnesium citrate adds modest support for ATP-dependent reactions.

The formula is primarily an herbal kidney product rather than an energy supplement. Buchu, uva ursi, dandelion, and nettle do not provide strong evidence for energy or stamina, and their diuretic focus may be counterproductive for some users.

Study evidence
Magnesium Supportive 4 studies
Riboflavin Mixed 6 studies
Thiamin Disputed 12 studies
Vitamin B12 Disputed 14 studies
General Health
General Health
Impact
Moderate effect
D- Goal FitC- Strength of SupportD- CoverageC Formula Quality
Vitamin B12 · 525 mcgMagnesium · 75 mgVitamin K · 210 mcg

The kidney-focused herbal blend is a niche formula rather than a balanced general-health product. B vitamins and magnesium provide some foundational value, but the product omits most major vitamins, minerals, and essential fats.

Botanical extracts are individually listed but lack standardization details and appear at modest amounts. Uva ursi is not suited to prolonged routine use, and the high vitamin K1 amount can interfere with warfarin management.

Study evidence
Magnesium Supportive 114 studies
Vitamin K Supportive 34 studies

Ingredients

IngredientAmount per serving
Total Carbohydrates
1 Gram(s)
Vitamin K1
210 mcg
Thiamine (Thiamine Hydrochloride, Vitamin B1)
 25 mg
Riboflavin (Vitamin B2)
 30 mg
Vitamin B6 (Pyridoxine Hydrochloride)
 37 mg
Vitamin B12 (Cyanocobalamin)
 525 mcg
Calcium
42 mg
Magnesium (Magnesium Citrate)
 75 mg
Copper (Chlorophyllin Copper Complex Sodium)
 0.8 mg
Buchu leaf extract
100 mg
Yellowdock root
50 mg
Uva Ursi leaf extract
40 mg
Dandelion
40 mg
Stinging Nettles
40 mg
Astaxanthin
500 mcg
Adults 18–50
Report overview
Vitamin B6 (Pyridoxine Hydrochloride) · 37 mg OverallScore68
C+ Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyF Value

Pyridoxine hydrochloride is less direct than active P-5-P, though riboflavin may support its conversion. The 37 mg dose fits the preferred range and is clearly delivered in two capsules. The botanical kidney formula is costly when judged mainly as a source of synthetic-form B6.

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Riboflavin (Vitamin B2) · 30 mg OverallScore68
D- Active Ingredient Quality & BioavailabilityA- Dose, Safety & Label TransparencyB+ Value

The 30 mg standard riboflavin dose provides moderate metabolic support, though it requires conversion to the active coenzyme form. The capsule format supports efficient release, and no artificial colors, flavors, or synthetic sweeteners are listed. Cost efficiency is favorable for the potency supplied.

View ingredientView products
Thiamin (Thiamine Hydrochloride, Vitamin B1) · 25 mg OverallScore65
B- Active Ingredient Quality & BioavailabilityB- Dose, Safety & Label TransparencyD- Value

Thiamine hydrochloride supplies a standard form at a moderate dose in a botanical kidney-support formula. The capsule is conventional, while the exact active amount is clearly disclosed outside the herbs. Its near-median serving cost and small thiamine dose make it poor value for targeted B1 support.

View ingredientView products
Loading alternative details
78 Performance

Methylfolate B Complex

Codeage
<p>Active riboflavin, B6, methylfolate, and methylcobalamin improve B-vitamin form quality over the original. The concentrated formula is suited to targeted methylation support and provides neither magnesium nor the original kidney-focused herbs.</p>
78 Performance

Homocysteine Resist

Life Extension
<p>Active B6, methylfolate, and methylcobalamin create a more transparent, focused B-vitamin formula. High folate and vitamin B6 make prolonged unsupervised use a concern, and the product does not serve the original kidney-cleanse purpose.</p>
74 Performance

HomocysteX Plus

Seeking Health
<p>Active B6, riboflavin, folate, and trimethylglycine provide a coherent and clearly dosed methylation formula. The B12 form is not fully identified, and the product omits magnesium plus the original botanical blend.</p>
78 Budget

B-50 Complex

21st Century
<p>The far lower serving cost provides broad B-vitamin coverage with clearer active amounts than the original herbal blend. Conventional forms and high vitamin B6 limit long-term use, while the formula provides no kidney-focused herbs or magnesium.</p>
63 Budget

Ultra B-100 Complex

Mason Natural
<p>The much lower serving cost retains broad B-vitamin coverage but uses mostly conventional forms. Excessive pyridoxine and a vague food base make it unbalanced, and it does not replace the original kidney-oriented botanicals.</p>
83 Budget

Living Calcium Advanced

Garden of Life
<p>The lower serving cost provides magnesium, vitamin D3, vitamin K2, calcium, and trace minerals with clearer amounts. It is a bone formula rather than a kidney product, and the high mineral load plus aggressive vitamin B6 reduce routine-use flexibility.</p>
71 Value

Neurobion USA High Potency Formula

OTC Pharmaceutical Products
<p>The lower serving cost and simple three-vitamin formula make dosing clearer than the original multi-herb product. All forms are conventional and vitamin B6 is extremely high, while no kidney-focused ingredients are supplied.</p>
82 Value

Women's Iron Restore

Carlson
<p>Chelated iron, vitamin C, copper, molybdenum, and B vitamins provide substantial nutrients at a lower serving cost. High iron and preformed vitamin A require a documented need, and the formula is not an alternative for kidney cleansing.</p>
69 Value

Super B-Complex

Pure Synergy
<p>Broad B-vitamin coverage and meaningful choline provide a simpler metabolic formula. Several forms are unspecified, the serving cost is above the original, and the formula omits magnesium and kidney-focused herbs.</p>
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Randomised clinical trial: high-dose oral thiamine versus placebo for chronic fatigue in patients with quiescent inflammatory bowel disease.
    Bager P; Hvas CL; Rud CL; Dahlerup JF · Alimentary pharmacology & therapeutics · 2021
    Randomized trial40 participantsEnergy forThiamin
  2. High-dose oral thiamine versus placebo for chronic fatigue in patients with primary biliary cholangitis: A crossover randomized clinical trial.
    Bager P; Bossen L; Gantzel R; Grønbæk H · PloS one · 2024
    Randomized trial36 participantsEnergy forThiamin
  3. Effects of thiamine supplementation on exercise-induced fatigue.
    Suzuki M; Itokawa Y · Metabolic brain disease · 1996
    Randomized trial16 participantsEnergy forThiamin
  4. Physicochemical properties of and volatile compounds in riboflavin fortified cloudy apple juice; study of its effect on job fatigue among Egyptian construction workers.
    Fouad S; Ibrahim GE; Hussein AMS; Ibrahim FA; El Gendy A · Heliyon · 2021
    Non-randomized trialEnergy forRiboflavin
  5. Vitamin B status in patients with chronic fatigue syndrome.
    Heap LC; Peters TJ; Wessely S · Journal of the Royal Society of Medicine · 1999
    Case-control study30 participantsEnergy forRiboflavin
  6. Magnesium-L-threonate improves sleep quality and daytime functioning in adults with self-reported sleep problems: A randomized controlled trial.
    Hausenblas HA; Lynch T; Hooper S; Shrestha A; Rosendale D; Gu J · Sleep medicine: X · 2025
    Randomized trial80 participantsEnergy forMagnesium
  7. Total magnesium intake and risk of frailty in older women.
    Struijk EA; Fung TT; Bischoff-Ferrari HA; Willett WC; Lopez-Garcia E · Journal of cachexia, sarcopenia and muscle · 2024
    Cohort study81,524 participantsEnergy forMagnesium
  8. Red blood cell magnesium and chronic fatigue syndrome.
    Cox IM; Campbell MJ; Dowson D · Lancet (London, England) · 1991
    Randomized trial32 participantsEnergy forMagnesium
  9. Exercise, magnesium and immune function.
    Laires MJ; Monteiro C · Magnesium research · 2008
    Narrative reviewEnergy forMagnesium
  10. B-vitamins, related vitamers, and metabolites in patients with quiescent inflammatory bowel disease and chronic fatigue treated with high dose oral thiamine.
    Bager P; Hvas CL; Hansen MM; Ueland P; Dahlerup JF · Molecular medicine (Cambridge, Mass.) · 2023
    Observational studyEnergy forRiboflavin
  11. Metabolic features of chronic fatigue syndrome.
    Naviaux RK; Naviaux JC; Li K; Bright AT; Alaynick WA; Wang L; Baxter A; Nathan N; Anderson W; Gordon E · Proceedings of the National Academy of Sciences of the United States of America · 2024
    Case-control study84 participantsEnergy forRiboflavin
  12. Effectiveness of Riboflavin in Inherited Metabolic Diseases: A Systematic Review
    Bregje Jaeger, Nina N Stolwijk, Femke Aaldering, Charlotte A Ruys, Marije Smits, Nicole I Wolf, Carla E M Hollak, Annet M Bosch · Journal of Inherited Metabolic Disease · 2026
    Systematic review381 studies pooledEnergy forRiboflavin
  13. Influence of thiamin supplementation on the health and general well-being of an elderly Irish population with marginal thiamin deficiency.
    Smidt LJ; Cremin FM; Grivetti LE; Clifford AJ · Journal of gerontology · 1991
    Randomized trial80 participantsEnergy forThiamin
  14. Dietary reference values for thiamin.
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA); Turck D; Bresson JL; Burlingame B; Dean T; Fairweather-Tait S; Heinonen M; Hirsch-Ernst KI; Mangelsdorf I; McArdle HJ; Naska A; Nowicka G; Pentieva K; Sanz Y; Siani A; Sjödin A; Stern M; Tomé D; Van Loveren H; Vinceti M; Willatts P; Lamberg-Allardt C; Przyrembel H; Tetens I; Gudelj Rakic J; Ioannidou S; de Sesmaisons-Lecarré A; Forss AC; Neuhäuser-Berthold M · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusEnergy forThiamin
  15. Long-term maintenance treatment with 300 mg thiamine for fatigue in patients with inflammatory bowel disease: results from an open-label extension of the TARIF study.
    Bager P; Hvas CL; Rud CL; Dahlerup JF · Scandinavian journal of gastroenterology · 2022
    Randomized trialEnergy forThiamin
  16. A new perspective on vitamin B12 deficiency in rheumatology: a case-based review.
    Dułak NA; Rytlewska M; Jaskólska M; Chmielewski M · Rheumatology international · 2024
    Case series3 participantsEnergy forVitamin B12
  17. Effects of Vitamin B12 Supplementation on Cognitive Function, Depressive Symptoms, and Fatigue: A Systematic Review, Meta-Analysis, and Meta-Regression.
    Markun S; Gravestock I; Jäger L; Rosemann T; Pichierri G; Burgstaller JM · Nutrients · 2021
    Meta-analysis6,276 participants16 studies pooledEnergy forVitamin B12
  18. Patients' experiences with methylcobalamin injections in amyotrophic lateral sclerosis.
    Zubair AS; Saab L; Scharer K; Khokhar B · Brain circulation · 2024
    Qualitative study5 participantsEnergy forVitamin B12
  19. Cobalamin deficiency: clinical picture and radiological findings.
    Briani C; Dalla Torre C; Citton V; Manara R; Pompanin S; Binotto G; Adami F · Nutrients · 2014
    Narrative reviewEnergy forVitamin B12
  20. Vitamin B12 Deficiency: Common Questions and Answers.
    Patel H; McGuirk R · American family physician · 2025
    Narrative reviewEnergy forVitamin B12
  21. Perioperative systemic magnesium to minimize postoperative pain: a meta-analysis of randomized controlled trials.
    De Oliveira GS; Castro-Alves LJ; Khan JH; McCarthy RJ · Anesthesiology · 2013
    Meta-analysis1,257 participants20 studies pooledGeneral Health forMagnesium
  22. Long-term outcome after intravenous magnesium sulphate in suspected acute myocardial infarction: the second Leicester Intravenous Magnesium Intervention Trial (LIMIT-2).
    Woods KL; Fletcher S · Lancet (London, England) · 1994
    Randomized trial2,316 participantsGeneral Health forMagnesium
  23. Association of magnesium sulfate use with mortality in critically ill patients with sepsis: a retrospective propensity score-matched cohort study.
    Gu WJ; Duan XJ; Liu XZ; Cen Y; Tao LY; Lyu J; Yin HY · British journal of anaesthesia · 2023
    Cohort study10,999 participantsGeneral Health forMagnesium
  24. Hypomagnesemia and Mortality in Incident Hemodialysis Patients.
    Li L; Streja E; Rhee CM; Mehrotra R; Soohoo M; Brunelli SM; Kovesdy CP; Kalantar-Zadeh K · American journal of kidney diseases : the official journal of the National Kidney Foundation · 2016
    Cohort study9,359 participantsGeneral Health forMagnesium
  25. The effects of magnesium supplementation on abnormal uterine bleeding, alopecia, quality of life, and acne in women with polycystic ovary syndrome: a randomized clinical trial.
    Jaripur M; Ghasemi-Tehrani H; Askari G; Gholizadeh-Moghaddam M; Clark CCT; Rouhani MH · Reproductive biology and endocrinology : RB&E · 2022
    Randomized trial64 participantsGeneral Health forMagnesium
  26. Dietary vitamin K intake associates with reduced all-cause mortality in non-alcoholic fatty liver disease patients.
    Huang Y; Zhu X; Han L; Hu H · Scientific reports · 2025
    Cohort study7,857 participantsGeneral Health forVitamin K
  27. Vitamin K status, cardiovascular disease, and all-cause mortality: a participant-level meta-analysis of 3 US cohorts.
    Shea MK; Barger K; Booth SL; Matuszek G; Cushman M; Benjamin EJ; Kritchevsky SB; Weiner DE · The American journal of clinical nutrition · 2020
    Meta-analysis3,891 participants3 studies pooledGeneral Health forVitamin K
  28. The Effect of Topical Vitamin K1 on the Treatment of Cetuximab-Induced Skin Rashes in Metastatic Colorectal Cancer Patients.
    Roayaei M; Rezaei M; Najafizade N · Advanced biomedical research · 2024
    Randomized trial49 participantsGeneral Health forVitamin K
  29. Effect of vitamin K on improving post‑kidney transplant outcomes: a meta‑analysis.
    Sun Z; Zhu K; Liang G; Yan F; Chao S; Jia L; Niu Y · Experimental and therapeutic medicine · 2023
    Meta-analysis7 studies pooledGeneral Health forVitamin K
  30. Vitamin K1 intake is associated with lower risk for all-cause and cardiovascular disease mortality in community-dwelling older Australian women.
    Dupuy M; Radavelli-Bagatini S; Zhong L; Dalla Via J; Zhu K; Blekkenhorst LC; Bondonno NP; Linneberg A; Bellinge JW; Schultz C; Courtney W; Prince RL; Hodgson JM; Lewis JR; Sim M · Nutrition, metabolism, and cardiovascular diseases : NMCD · 2024
    Cohort study1,436 participantsGeneral Health forVitamin K