Ortho Thyroid

Ortho Thyroid

Protocol For Life Balance4.7 (696 ratings)
Format:Capsule Quantity: 90 Capsule(s) · 45 servings
Goals
$23.00 $0.51 per serving

Product analysis

62 out of 100

Ortho Thyroid supplies iodine and supporting nutrients for normal thyroid and immune functions when intake is low.

AI assessment of the formula, label and price. How scoring works

Nutrient Quality52

The iodine and zinc forms appear favorable for absorption. Quality across the rest of the mix remains less certain, and the folate and tyrosine forms are not disclosed.

Ingredient Transparency93

All ingredient amounts and most forms are stated. The missing folate and tyrosine forms leave a small but meaningful gap for product comparisons.

Value For Money40

The iodine and copper comparisons suggest moderate value, while zinc looks less economical. Value from the remaining nutrients and herbs is uncertain.

Customer Satisfaction79

Customer ratings are favorable across a substantial body of feedback. That gives a useful satisfaction picture without proving thyroid or hormone effects.

Product Focus51

The clearest role is supporting normal thyroid function when iodine intake is low. The broader aims rely mainly on filling nutrient gaps and do not establish faster metabolism or higher testosterone with adequate intake.

Format
Capsule
Container
90 Capsule(s)
Per serving
$0.51
Customer rating
4.7 · 696 ratings
Report analysis

Goals

Impact
Moderate effect
C- Ingredient FitF PathwaysA+ EvidenceA+ Formulation Logic
Vitamin B12 · 60 mcgVitamin B6 · 2 mgZinc · 25 mg
Study evidence
Iodine Mixed 17 studies
Selenium Mixed 28 studies
Vitamin B6 Supportive 16 studies
Zinc Supportive 12 studies
Hair Health
Impact
Moderate effect
C- Ingredient FitF PathwaysA+ EvidenceA+ Formulation Logic
Zinc · 25 mg
Study evidence
Copper Adverse 4 studies
Folate Mixed 15 studies
Iodine No effect 1 study
Selenium Disputed 7 studies
Zinc Supportive 22 studies
Everyday Health
Impact
High effect
C+ Ingredient FitC PathwaysB+ EvidenceA+ Formulation Logic
Folate · 680 mcg DFEVitamin B12 · 60 mcgSelenium · 50 mcgAshwagandha · 50 mgZinc · 25 mg
Study evidence
Folate Supportive 80 studies
Selenium Supportive 70 studies
Zinc Supportive 60 studies
Immunity
Impact
High effect
C Ingredient FitF PathwaysA+ EvidenceA+ Formulation Logic
Zinc · 25 mgSelenium · 50 mcg
Study evidence
Selenium Mixed 37 studies
Zinc Supportive 73 studies
Fitness
Impact
Lower effect
F Ingredient FitF PathwaysD+ EvidenceA+ Formulation Logic
Ashwagandha · 50 mg
Study evidence
Zinc Supportive 7 studies
Skin Health
Impact
Moderate effect
D Ingredient FitF PathwaysA- EvidenceA+ Formulation Logic
Zinc · 25 mgCopper · 1 mgSelenium · 50 mcg
Study evidence
Copper Supportive 16 studies
Selenium Supportive 22 studies
Zinc Supportive 66 studies

Ingredients

IngredientAmount per servingScore
Vitamin B6 (Pyridoxine Hydrochloride)
2 mg
Folate
680 mcg DFE
Vitamin B12 (Methylcobalamin)
60 mcg
Iodine (Potassium Iodide)
225 mcg 90
Zinc (L-OptiZinc Zinc L-Methionine Complex)
25 mg 82
Selenium (L-Selenomethionine)
50 mcg
Copper (Copper Amino Acid Chelate)
1 mg 62
L-Tyrosine
1 Gram(s)
Guggul (Commiphora mukul) (gum resin) standardized extract (Guggulsterones)
75 mg
Ashwagandha Root Extract (Withanolides)
50 mg 85
Gluten Free Adults 18–50 Dairy Free Women
Report overview
A+ Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyD+ Value
The serving provides 225 mcg iodine at a higher cost per serving. The iodine comes from potassium iodide.
How this ingredient is rated

Active Ingredient Quality & Bioavailability100

The iodine comes from potassium iodide. No marine source is indicated, so seaweed-specific purity concerns do not apply to the stated source.
Iodine Form & Bioavailability
The iodine comes from potassium iodide.
Marine Source Purity & Sourcing
No marine source is indicated, so seaweed-specific purity concerns do not apply to the stated source.

Dose, Safety & Label Transparency100

The serving provides 225 mcg iodine, an amount suited to daily thyroid maintenance. The 225 mcg per serving is below the adult upper intake level of 1,100 mcg.
Dosage Efficacy for Daily Support
The serving provides 225 mcg iodine, an amount suited to daily thyroid maintenance.
Dosage Safety & Upper Limits
The 225 mcg per serving is below the adult upper intake level of 1,100 mcg.
Elemental Iodine Transparency
The iodine amount per serving is stated.

Value50

The cost per serving is higher.
Price Per Effective Serving
The cost per serving is higher.
A+ Active Ingredient Quality & BioavailabilityA Dose, Safety & Label TransparencyF Value
The serving provides 25 mg of zinc at a high cost per serving. It uses Zinc L-Monomethionine Sulfate. It also provides 1 mg copper.
How this ingredient is rated

Active Ingredient Quality & Bioavailability100

It uses Zinc L-Monomethionine Sulfate.
Zinc Form Bioavailability
It uses Zinc L-Monomethionine Sulfate.

Dose, Safety & Label Transparency91

The serving provides 25 mg of zinc per serving. The serving also contains 1 mg copper.
Elemental Dose Transparency
The elemental zinc amount and source are stated.
Zinc Dosage Safety & Effectiveness
The serving provides 25 mg of zinc per serving.
Zinc-to-Copper Mineral Balance
The serving also contains 1 mg copper.

Value30

The cost per serving is high.
Price Per Serving Efficiency
The cost per serving is high.
C- Active Ingredient Quality & BioavailabilityB- Dose, Safety & Label TransparencyD+ Value
The serving provides 1 mg of copper at a moderate cost per serving. The copper source is Copper Amino Acid Chelate. The specific amino acid in the chelate is not named.
How this ingredient is rated

Active Ingredient Quality & Bioavailability58

The copper source is Copper Amino Acid Chelate. The specific amino acid in the chelate is not named.
Copper Form Bioavailability
The copper source is Copper Amino Acid Chelate. The specific amino acid in the chelate is not named.
Elemental Copper Labeling Clarity
The label states both the elemental copper amount and its source.

Dose, Safety & Label Transparency71

The serving supplies 1 mg of copper. It also provides 25 mg of zinc per serving.
Copper Dosage Safety & Efficacy
The serving supplies 1 mg of copper.
Zinc-to-Copper Balance
The serving contains 25 mg zinc alongside 1 mg copper.

Value50

The cost per serving is moderate.
Price Per Serving Efficiency
The cost per serving is moderate.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Effects of multi-herb and ashwagandha root formulas on stress modulation: a randomized, double-blind, placebo-controlled clinical study.
    McKinney E; Stewart J; Kewalramani R; Singh S · Trials · 2026
    Randomized trial186 participantsEnergy forAshwagandha
  2. Efficacy and Safety of Low-Dose Ashwagandha Supplementation on Exercise Endurance: A Randomized, Placebo-Controlled, Double-Blind, Clinical Trial.
    Prajapati H; Satia M; Shah D; Basera I; Shah T · Phytotherapy research : PTR · 2026
    Randomized trialEnergy forAshwagandha
  3. Acute and Repeated Ashwagandha Supplementation Improves Markers of Cognitive Function and Mood.
    Leonard M; Dickerson B; Estes L; Gonzalez DE; Jenkins V; Johnson S; Xing D; Yoo C; Ko J; Purpura M; Jäger R; Faries M; Kephart W; Sowinski R; Rasmussen CJ; Kreider RB · Nutrients · 2024
    Randomized trial59 participantsEnergy forAshwagandha
  4. Enhancing healthspan with Ashwagandha (Withania somnifera): a comprehensive review of its multifaceted geroprotective benefits.
    Vittal M; Vinciguerra M · Biogerontology · 2025
    Narrative reviewEnergy forAshwagandha
  5. Safety and Efficacy of Ashwagandha Root Extract on Cognition, Energy and Mood Problems in Adults: Prospective, Randomized, Placebo-Controlled Study.
    Kale S; Lopresti A; Suri R; Garg N; Langade D · Journal of psychoactive drugs · 2026
    Randomized trial120 participantsEnergy forAshwagandha
  6. Association of radioactive iodine treatment with survivorship symptoms and primary care utilisation in women of reproductive age with thyroid cancer: a retrospective cohort study.
    Devanarayan P; Hartman M; Partin M · Family medicine and community health · 2026
    Cohort study10,882 participantsEnergy forIodine
  7. Energy level and fatigue after surgery for thyroid cancer: A population-based study of patient-reported outcomes.
    Hughes DT; Reyes-Gastelum D; Kovatch KJ; Hamilton AS; Ward KC; Haymart MR · Surgery · 2020
    Cohort study2,584 participantsEnergy forIodine
  8. Health-Related Quality of Life in Differentiated Thyroid Cancer Survivors: A Cross-Sectional Study From Turkey.
    Gültekin A; Kahraman MY; Şengöz T; Şimşek FS · Head & neck · 2026
    Cross-sectional study202 participantsEnergy forIodine
  9. A new perspective on vitamin B12 deficiency in rheumatology: a case-based review.
    Dułak NA; Rytlewska M; Jaskólska M; Chmielewski M · Rheumatology international · 2024
    Case series3 participantsEnergy forVitamin B12
  10. Effects of Vitamin B12 Supplementation on Cognitive Function, Depressive Symptoms, and Fatigue: A Systematic Review, Meta-Analysis, and Meta-Regression.
    Markun S; Gravestock I; Jäger L; Rosemann T; Pichierri G; Burgstaller JM · Nutrients · 2021
    Meta-analysis6,276 participants16 studies pooledEnergy forVitamin B12
  11. Patients' experiences with methylcobalamin injections in amyotrophic lateral sclerosis.
    Zubair AS; Saab L; Scharer K; Khokhar B · Brain circulation · 2024
    Qualitative study5 participantsEnergy forVitamin B12
  12. Cobalamin deficiency: clinical picture and radiological findings.
    Briani C; Dalla Torre C; Citton V; Manara R; Pompanin S; Binotto G; Adami F · Nutrients · 2014
    Narrative reviewEnergy forVitamin B12
  13. Vitamin B12 Deficiency: Common Questions and Answers.
    Patel H; McGuirk R · American family physician · 2025
    Narrative reviewEnergy forVitamin B12
  14. A randomized, double blind, placebo controlled study to evaluate the effects of ashwagandha (Withania somnifera) extract on sleep quality in healthy adults.
    Deshpande A; Irani N; Balkrishnan R; Benny IR · Sleep medicine · 2021
    Randomized trial150 participantsEveryday Health forAshwagandha
  15. Effects of Ashwagandha ( Withania somnifera) standardized root extract on physical endurance and VO 2max in healthy adults performing resistance training: An eight-week, prospective, randomized, double-blind, placebo-controlled study.
    Verma N; Gupta SK; Patil S; Tiwari S; Mishra AK · F1000Research · 2024
    Randomized trial80 participantsEveryday Health Fitness forAshwagandha
  16. Efficacy of Ashwagandha (Withania somnifera [L.] Dunal) in improving cardiorespiratory endurance in healthy athletic adults.
    Choudhary B; Shetty A; Langade DG · Ayu · 2016
    Randomized trial50 participantsEveryday Health Fitness forAshwagandha
  17. Withania somnifera (L.) Dunal as Add-On Therapy for COPD Patients: A Randomized, Placebo-Controlled, Double-Blind Study.
    Singh P; Salman KA; Shameem M; Warsi MS · Frontiers in pharmacology · 2022
    Randomized trial150 participantsEveryday Health forAshwagandha
  18. Effect of Ashwagandha (Withania somnifera) extract on sleep: A systematic review and meta-analysis.
    Cheah KL; Norhayati MN; Husniati Yaacob L; Abdul Rahman R · PloS one · 2021
    Meta-analysis400 participants5 studies pooledEveryday Health forAshwagandha
  19. Intakes of Folate, Vitamin B6, and Vitamin B12 in Relation to All-Cause and Cause-Specific Mortality: A National Population-Based Cohort.
    Bo Y; Xu H; Zhang H; Zhang J; Wan Z; Zhao X; Yu Z · Nutrients · 2022
    Cohort study55,569 participantsEveryday Health forFolate
  20. The responsiveness of plasma homocysteine to small increases in dietary folic acid: a primary care study.
    Schorah CJ; Devitt H; Lucock M; Dowell AC · European journal of clinical nutrition · 1998
    Randomized trial119 participantsEveryday Health forFolate