CellularActive Coenzyme B-Complex

CellularActive Coenzyme B-Complex

Bluebonnet4.8 (198 ratings)
Format:Capsule Quantity: 100 Capsule(s) · 100 servings
Goals
$28.76 $0.28 per serving

Product analysis

68 out of 100

CellularActive Coenzyme B-Complex supports normal energy use and blood formation when B-vitamin intake falls short. Several vitamin blends omit their proportions, so the label cannot show how much of each form you receive.

AI assessment of the formula, label and price. How scoring works

Nutrient Quality71

Several B-vitamin forms are favorable choices, including B6, biotin and B5. Mixed forms and incomplete information for other ingredients limit a close comparison of the full formula.

Ingredient Transparency77

All ingredient amounts and almost all forms are listed. The proportions of several mixed vitamin forms are missing, leaving their individual contributions unclear.

Value For Money51

Riboflavin and B6 offer favorable value at the serving price. B5 is comparatively costly, and value for some other ingredients remains unresolved.

Customer Satisfaction75

Customer ratings indicate very high satisfaction. The smaller pool of customer ratings leaves more uncertainty about wider satisfaction.

Product Focus66

The B-vitamin blend covers several related nutritional functions. Its clearest benefits come from correcting low intake, without established added mood, memory or energy benefits once intake is adequate.

Format
Capsule
Container
100 Capsule(s)
Per serving
$0.28
Customer rating
4.8 · 198 ratings
Report analysis

Goals

Impact
High effect
B+ Ingredient FitF PathwaysB+ EvidenceA+ Formulation Logic
Vitamin B5 · 25 mgRiboflavin · 25 mgThiamin · 25 mgVitamin B12 · 250 mcg
Study evidence
Thiamin Disputed 12 studies
Impact
High effect
B+ Ingredient FitF PathwaysA+ EvidenceA+ Formulation Logic
Biotin · 300 mcgNiacin · 25 mgVitamin B12 · 250 mcgRiboflavin · 25 mgThiamin · 25 mgVitamin B5 · 25 mgVitamin B6 · 25 mg
Study evidence
Biotin Supportive 5 studies
Niacin Supportive 17 studies
Thiamin Supportive 11 studies
Vitamin B6 Supportive 16 studies

Ingredients

IngredientAmount per servingScore
Thiamin (Cocarboxylase, Thiamine Mononitrate)
25 mg 65
Riboflavin (Riboflavin 5-Phosphate)
25 mg 79
Niacin (Inositol Hexaniacinate, Niacinamide)
25 mg 66
Vitamin B6 (Pyridoxal 5-Phosphate, Pyridoxine Hydrochloride)
25 mg 82
Folate ((6S)-5-Methyltetrahydrofolic Acid, Folic Acid)
600 mcg DFE
Vitamin B12 (Methylcobalamin)
250 mcg 67
Biotin (D-Biotin)
300 mcg 66
Pantothenic Acid (Calcium D-Pantothenate)
25 mg 61
Inositol (Inositol Hexanicotinate)
25 mg
Para-Aminobenzoic Acid
25 mg 78
Gluten Free Adults 18–50 Vegan Kosher Dairy Free Sugar Free Vegetarian
Report overview
A+ Ingredient Form & Label QualityC Dose, Safety & Label TransparencyA- Value
A serving provides 25 mg of B6 at a moderate cost per mg. The amount exceeds the European adult upper limit of 12 mg per day. The B6 sources are Pyridoxal 5-Phosphate and Pyridoxine Hydrochloride but their proportions are unknown.
How this ingredient is rated

Ingredient Form & Label Quality100

The B6 sources are Pyridoxal 5-Phosphate and Pyridoxine Hydrochloride but their proportions are unknown. No artificial colors, titanium dioxide or talc are indicated in the available additive findings.
Vitamin B6 Form Identification
The B6 sources are Pyridoxal 5-Phosphate and Pyridoxine Hydrochloride but their proportions are unknown.
Clean Label and Excipient Purity
No artificial colors, titanium dioxide or talc are indicated in the available additive findings.

Dose, Safety & Label Transparency60

25 mg per serving exceeds the European adult upper limit of 12 mg per day; total daily intake also includes food and other supplements. The source is named.
Vitamin B6 Dose & Safety Policy
25 mg per serving exceeds the European adult upper limit of 12 mg per day; total daily intake also includes food and other supplements.
Label Transparency
The label identifies Pyridoxal 5-Phosphate and Pyridoxine Hydrochloride as the B6 sources.

Value88

The cost per mg of B6 is moderate.
Vitamin B6 Price Efficiency
The cost per mg of B6 is moderate.
PABA · 25 mg OverallScore78
B+ Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyD- Value
The serving contains 25 mg of PABA. The whole-product cost per 100 mg of PABA is high; it may overstate the cost attributable to PABA. PABA is named, but no pharmaceutical grade or purity claim is available. The other ingredients do not list artificial colors, titanium dioxide or hydrogenated oils.
How this ingredient is rated

Active Ingredient Quality & Bioavailability80

PABA is named, but no pharmaceutical grade or purity claim is available.
PABA Source & Grade
PABA is named, but no pharmaceutical grade or purity claim is available.

Dose, Safety & Label Transparency95

The serving contains 25 mg of PABA. The other ingredients do not list artificial colors, titanium dioxide or hydrogenated oils.
PABA Dosage Alignment
The serving contains 25 mg of PABA.
Label Disclosure Clarity
The PABA amount is stated as 25 mg per serving.
Additive and Excipient Quality
The other ingredients do not list artificial colors, titanium dioxide or hydrogenated oils.

Value40

The whole-product cost per 100 mg of PABA is high; it may overstate the cost attributable to PABA.
Price per 100mg PABA
The whole-product cost per 100 mg of PABA is high; it may overstate the cost attributable to PABA.
B Active Ingredient Quality & BioavailabilityC+ Dose, Safety & Label TransparencyD- Value
Each serving provides 25 mg of niacin. The price per serving is moderate to high for the niacin form. It combines inositol hexanicotinate and niacinamide, but their proportions are unknown.
How this ingredient is rated

Active Ingredient Quality & Bioavailability79

It combines inositol hexanicotinate and niacinamide, but their proportions are unknown.
Niacin Form & Goal Alignment
It combines inositol hexanicotinate and niacinamide, but their proportions are unknown.
Precursor Source Quality
The blend includes niacinamide and inositol hexanicotinate.

Dose, Safety & Label Transparency67

Each serving provides 25 mg of niacin. The blend includes forms used without flushing, though no no-flush claim is recorded.
Clarity of Chemical Form
Both forms are named, but their proportions are not disclosed.
Form-Specific Dosage Efficacy
Each serving provides 25 mg of niacin.
Flush Risk & Safety Labeling
The blend includes forms used without flushing, though no no-flush claim is recorded.

Value40

The price per serving is moderate to high for the niacin form.
Price Per Effective Serving
The price per serving is moderate to high for the niacin form.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Physicochemical properties of and volatile compounds in riboflavin fortified cloudy apple juice; study of its effect on job fatigue among Egyptian construction workers.
    Fouad S; Ibrahim GE; Hussein AMS; Ibrahim FA; El Gendy A · Heliyon · 2021
    Non-randomized trialEnergy forRiboflavin
  2. Vitamin B status in patients with chronic fatigue syndrome.
    Heap LC; Peters TJ; Wessely S · Journal of the Royal Society of Medicine · 1999
    Case-control study30 participantsEnergy forRiboflavin
  3. B-vitamins, related vitamers, and metabolites in patients with quiescent inflammatory bowel disease and chronic fatigue treated with high dose oral thiamine.
    Bager P; Hvas CL; Hansen MM; Ueland P; Dahlerup JF · Molecular medicine (Cambridge, Mass.) · 2023
    Observational studyEnergy forRiboflavin
  4. Metabolic features of chronic fatigue syndrome.
    Naviaux RK; Naviaux JC; Li K; Bright AT; Alaynick WA; Wang L; Baxter A; Nathan N; Anderson W; Gordon E · Proceedings of the National Academy of Sciences of the United States of America · 2024
    Case-control study84 participantsEnergy forRiboflavin
  5. Effectiveness of Riboflavin in Inherited Metabolic Diseases: A Systematic Review
    Bregje Jaeger, Nina N Stolwijk, Femke Aaldering, Charlotte A Ruys, Marije Smits, Nicole I Wolf, Carla E M Hollak, Annet M Bosch · Journal of Inherited Metabolic Disease · 2026
    Systematic review381 studies pooledEnergy Metabolism Support forRiboflavin
  6. Influence of thiamin supplementation on the health and general well-being of an elderly Irish population with marginal thiamin deficiency.
    Smidt LJ; Cremin FM; Grivetti LE; Clifford AJ · Journal of gerontology · 1991
    Randomized trial80 participantsEnergy forThiamin
  7. Randomised clinical trial: high-dose oral thiamine versus placebo for chronic fatigue in patients with quiescent inflammatory bowel disease.
    Bager P; Hvas CL; Rud CL; Dahlerup JF · Alimentary pharmacology & therapeutics · 2021
    Randomized trial40 participantsEnergy forThiamin
  8. Dietary reference values for thiamin.
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA); Turck D; Bresson JL; Burlingame B; Dean T; Fairweather-Tait S; Heinonen M; Hirsch-Ernst KI; Mangelsdorf I; McArdle HJ; Naska A; Nowicka G; Pentieva K; Sanz Y; Siani A; Sjödin A; Stern M; Tomé D; Van Loveren H; Vinceti M; Willatts P; Lamberg-Allardt C; Przyrembel H; Tetens I; Gudelj Rakic J; Ioannidou S; de Sesmaisons-Lecarré A; Forss AC; Neuhäuser-Berthold M · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusEnergy forThiamin
  9. Effects of thiamine supplementation on exercise-induced fatigue.
    Suzuki M; Itokawa Y · Metabolic brain disease · 1996
    Randomized trial16 participantsEnergy forThiamin
  10. Long-term maintenance treatment with 300 mg thiamine for fatigue in patients with inflammatory bowel disease: results from an open-label extension of the TARIF study.
    Bager P; Hvas CL; Rud CL; Dahlerup JF · Scandinavian journal of gastroenterology · 2022
    Randomized trialEnergy forThiamin
  11. A new perspective on vitamin B12 deficiency in rheumatology: a case-based review.
    Dułak NA; Rytlewska M; Jaskólska M; Chmielewski M · Rheumatology international · 2024
    Case series3 participantsEnergy forVitamin B12
  12. Effects of Vitamin B12 Supplementation on Cognitive Function, Depressive Symptoms, and Fatigue: A Systematic Review, Meta-Analysis, and Meta-Regression.
    Markun S; Gravestock I; Jäger L; Rosemann T; Pichierri G; Burgstaller JM · Nutrients · 2021
    Meta-analysis6,276 participants16 studies pooledEnergy forVitamin B12
  13. Patients' experiences with methylcobalamin injections in amyotrophic lateral sclerosis.
    Zubair AS; Saab L; Scharer K; Khokhar B · Brain circulation · 2024
    Qualitative study5 participantsEnergy forVitamin B12
  14. Cobalamin deficiency: clinical picture and radiological findings.
    Briani C; Dalla Torre C; Citton V; Manara R; Pompanin S; Binotto G; Adami F · Nutrients · 2014
    Narrative reviewEnergy forVitamin B12
  15. Vitamin B12 Deficiency: Common Questions and Answers.
    Patel H; McGuirk R · American family physician · 2025
    Narrative reviewEnergy forVitamin B12
  16. Biotin and contribution to normal energy-yielding metabolism: evaluation of a health claim pursuant to Article 14 of Regulation (EC) No 1924/2006.
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusMetabolism Support forBiotin
  17. Pregnancy and lactation alter biomarkers of biotin metabolism in women consuming a controlled diet.
    Perry CA; West AA; Gayle A; Lucas LK; Yan J; Jiang X; Malysheva O; Caudill MA · The Journal of nutrition · 2015
    Clinical trial75 participantsMetabolism Support forBiotin
  18. Survey of the effect of biotin on glycemic control and plasma lipid concentrations in type 1 diabetic patients in kermanshah in iran (2008-2009)
    Hemmati M, Babaei H, Abdolsalehei M · Oman Medical Journal · 2013
    Randomized trial70 participantsMetabolism Support forBiotin
  19. Chromium picolinate and biotin combination improves glucose metabolism in treated, uncontrolled overweight to obese patients with type 2 diabetes
    César A Albarracin, Bobby C Fuqua, James L Evans, Ira D Goldfine · Diabetes/Metabolism Research and Reviews · 2008
    Randomized trial348 participantsMetabolism Support forBiotin
  20. Biotin supplementation reduces plasma triacylglycerol and VLDL in type 2 diabetic patients and in nondiabetic subjects with hypertriglyceridemia
    Cristina Revilla-Monsalve, Iván Zendejas-Ruiz, Sergio Islas-Andrade, Armida Báez-Saldaña, Miguel Angel Palomino-Garibay, Pedro Martín Hernández-Quiróz, Cristina Fernandez-Mejia · Biomedicine & Pharmacotherapy · 2006
    Randomized trial33 participantsMetabolism Support forBiotin