BioCoenzymated Active B Complex

BioCoenzymated Active B Complex

Natural Factors4.8 (5,026 ratings)
Format:Capsule Quantity: 60 Capsule(s) · 60 servings
Goals
$20.97 $0.34 per serving

Product analysis

68 out of 100

BioCoenzymated Active B Complex supports normal energy use and can help fill B-vitamin gaps. Undisclosed proportions in the thiamin mixture make the relative amounts of its two forms unclear.

AI assessment of the formula, label and price. How scoring works

Nutrient Quality68

Several B vitamins use specifically identified forms with favorable quality findings. The thiamin mixture's proportions are unknown, and the information does not establish a quality advantage for every ingredient.

Ingredient Transparency74

All ingredient amounts and most forms are stated, making the formula easier to compare. Missing thiamin-mixture proportions leave the amounts of its two sources unclear.

Value For Money50

Value is more favorable for riboflavin and B6 than for B5 and choline. Missing comparisons for some other ingredients prevent a firm conclusion about the whole mix's value.

Customer Satisfaction91

Buyer ratings are strongly favorable. The large rating pool gives a broad picture of satisfaction without establishing extra benefits from active-form names.

Product Focus63

The clearest role is filling B-vitamin gaps that affect normal energy use, blood formation and nerve function. The many additional aims make it less concentrated on a single nutritional need.

Format
Capsule
Container
60 Capsule(s)
Per serving
$0.34
Customer rating
4.8 · 5,026 ratings
Report analysis

Goals

Impact
High effect
B Ingredient FitF PathwaysB+ EvidenceA+ Formulation Logic
Vitamin B5 · 100 mgRiboflavin · 10 mgThiamin · 30 mgVitamin B12 · 500 mcg

Riboflavin, B5, folate and niacin can help address fatigue linked to low intake, alongside vitamin B6. Their roles in normal metabolism do not establish extra energy when intake is adequate or make high amounts more effective. Vitamin B12 also contributes when low intake causes fatigue, with only a partial amount allowance here.

How this product is rated for Energy

Ingredient fit77

The relevant nutrients receive the main saved allowances. The declared amounts receive partial or mixed comparison allowances.
Goal fit
The relevant nutrients supply the main saved ingredient connection; other actives and broader product purposes affect focus.
Dose adequacy
The counted amounts receive partial or mixed allowances; smaller amounts limit the saved contribution without proving the ingredients ineffective.

Pathways0

No contribution is assigned to the configured energy pathways. Nutritional correction remains a distinct role.
Depth
No contribution is assigned to the configured energy pathways, despite the separate nutrient allowances.
Breadth
No configured energy pathway reaches the saved breadth criterion; this does not negate a nutrient’s role in correcting low intake.

Evidence81

The strongest relevant support concerns low-intake fatigue rather than extra energy with adequate nutrition. Saved allowances do not resolve the supplied limits for routine use.
Evidence strength
Vitamin B12 anchors the saved evidence finding; its allowance does not establish extra energy in adults with adequate intake.
Studied preparation
The counted preparations receive the saved comparison allowance, without establishing superior energy effects for a particular form.

Formulation logic100

The counted ingredients meet the minimum amount criterion and have no missing required partner or identified configured conflict.
Partner coverage
No required ingredient partner is missing for the counted ingredients.
Conflicts
No configured ingredient conflict was identified; this does not establish individual suitability.
Effective doses
The counted ingredients meet the saved minimum amount criterion; this threshold does not establish a fatigue-treatment dose.
Study evidence
Thiamin Disputed 12 studies
Impact
Highest effect
A- Ingredient FitB+ PathwaysB+ EvidenceA+ Formulation Logic
Folate · 680 mcg DFEVitamin B12 · 500 mcg

B vitamins contribute nutrients used in normal energy metabolism; folate contributes to normal blood formation. These nutrients can help fill dietary shortfalls; additional benefit above adequate intake is not established.

How this product is rated for Everyday Health

Ingredient fit88

The formula offers several nutritional contributions, with differing amounts and some ingredients outside the supported general-health roles.
Goal fit
Recognized nutrients support the general-health connection; other actives and wider product uses affect how specifically the formula addresses nutritional gaps.
Dose adequacy
The counted amounts reach the supplied comparison endpoints; higher quantities do not establish additional health benefit.

Pathways80

The strongest saved connection is energy metabolism cofactors, reflecting nutritional roles rather than demonstrated broad health outcomes.
Depth
The strongest saved connection is energy metabolism cofactors, reflecting nutritional roles rather than demonstrated broad health outcomes.
Breadth
The covered functions are energy metabolism cofactors, one-carbon metabolism and blood formation.

Evidence82

The evidence supports nutrient availability and correction of dietary gaps, rather than extra benefit when intake is adequate.
Evidence strength
Vitamin B9 (Folate) leads the saved evidence finding, with benefit limited to its supported nutritional role and filling low intake.
Studied preparation
The counted preparations match those recognized in the supplied comparison, without establishing superiority of a particular chemical form or delivery method.

Formulation logic100

No unmet partner requirement or specified conflict was identified, and the counted ingredients meet the supplied minimum amount comparisons.
Partner coverage
No counted ingredient has an unmet partner requirement in the supplied findings; this does not establish added benefit from combining ingredients.
Conflicts
No specified ingredient conflict was identified in the supplied findings.
Effective doses
All counted ingredients meet the supplied minimum amount comparison; this is not a proven threshold for broad health benefit.
Study evidence
Folate Supportive 80 studies
Impact
High effect
B Ingredient FitF PathwaysA+ EvidenceA+ Formulation Logic
Biotin · 250 mcgNiacin · 100 mgVitamin B12 · 500 mcgRiboflavin · 10 mgThiamin · 30 mgVitamin B5 · 100 mgVitamin B6 · 25 mg

The nutrients support normal energy-related processes, but physiological necessity does not establish that extra supplementation increases calorie burning. B vitamins help process nutrients into usable energy without demonstrating a higher whole-body energy expenditure.

How this product is rated for Metabolism Support

Ingredient fit80

Vitamin B1 (Thiamin) leads the included ingredient findings. The retained amounts make uneven contributions against their references.
Goal fit
The relevant ingredients share the formula with ingredients aimed at other health goals, reducing its concentration on this outcome.
Dose adequacy
The included amounts make partial contributions against their references, limiting the amount-based finding without establishing an effective metabolism-boosting dose.

Pathways0

The saved findings do not assign coverage to a specific rate-increasing route. Normal nutrient-dependent energy metabolism remains a separate outcome.
Depth
No specific route receives coverage in the saved findings, despite recognition of the ingredients’ normal metabolic roles.
Breadth
No route reaches meaningful coverage, leaving little breadth across distinct processes related to increased energy expenditure.

Evidence100

The leading nutrient references describe normal metabolic roles or selected-population findings, rather than a demonstrated general increase in calorie burning.
Evidence strength
Vitamin B1 (Thiamin) leads the included evidence finding; its normal role or specific study outcomes do not establish a general metabolism boost.
Studied preparation
The retained ingredients meet the saved preparation comparison; this does not establish that the product increases whole-body energy expenditure.

Formulation logic100

The retained ingredients meet the partner and minimum amount conditions, with no listed conflict triggered. These findings do not establish a lasting metabolic-rate or weight-loss effect.
Partner coverage
The retained ingredients have no unmet partner requirement; this does not establish extra calorie expenditure from combining them.
Conflicts
None of the listed ingredient-conflict conditions was triggered by the supplied facts.
Effective doses
All retained ingredients meet the minimum amount condition, which is not a proven dose for raising whole-body energy expenditure.
Study evidence
Biotin Supportive 5 studies
Niacin Supportive 17 studies
Thiamin Supportive 11 studies
Vitamin B6 Supportive 16 studies
Hair Health
Impact
Moderate effect
B- Ingredient FitF PathwaysB EvidenceA Formulation Logic
Biotin · 250 mcg

Biotin's relevance to shedding is mainly when a deficiency is responsible. Taking more when you already get enough isn't known to produce regrowth. B12 and the other B vitamins contribute nutritional cofactors, but that doesn't show an added hair benefit from combining them. The folate amount is unresolved in the available product facts.

How this product is rated for Hair Health

Ingredient fit70

Biotin may help deficiency-related shedding, rather than routine regrowth in adults who already get enough.
Goal fit
Biotin may help deficiency-related shedding, rather than routine regrowth in adults who already get enough.
Dose adequacy
Thiamin (B1) 30 mg, Riboflavin (B2) 10 mg, Pantothenic acid (B5) 100 mg per selected serving; these amounts are comparisons, not predictions of hair growth.

Pathways0

The ingredients relate to nutrient adequacy rather than a demonstrated direct effect on the listed hair mechanisms.
Depth
The ingredients relate to nutrient adequacy rather than a demonstrated direct effect on the listed hair mechanisms.
Breadth
The ingredients relate to nutrient adequacy rather than a demonstrated direct effect on the listed hair mechanisms.

Evidence78

The declared nutrient forms do not by themselves show superior hair growth. Nutritional roles should be distinguished from visible hair regrowth.
Evidence strength
Biotin may help deficiency-related shedding, rather than routine regrowth in adults who already get enough.
Studied preparation
The declared nutrient forms do not by themselves show superior hair growth.

Formulation logic92

No specific ingredient conflict or required missing partner is identified. Combining the ingredients does not by itself demonstrate an added hair benefit.
Partner coverage
No required missing partner is identified for the ingredients contributing here.
Conflicts
No particular ingredient conflict is identified in these product facts.
Effective doses
B12 supplies 500 mcg and niacin 100 mg per serving; biotin is 250 mcg. These amounts do not predict regrowth.
Study evidence
Biotin Supportive 4 studies
Folate Mixed 15 studies
Niacin Disputed 2 studies

Ingredients

IngredientAmount per servingScore
Thiamine (Benfotiamine, Thiamine Hydrochloride)
30 mg 67
Riboflavin (Riboflavin 5-Phosphate)
10 mg 82
Niacin (Inositol Hexanicotinate)
100 mg 62
Vitamin B6 (Pyridoxal 5-Phosphate)
25 mg 81
Folate ((6S)-5-Methyltetrahydrofolic Acid, Glucosamine Salt)
680 mcg DFE
Vitamin B12 (Methylcobalamin)
500 mcg 76
Biotin
250 mcg 59
Pantothenic Acid (Calcium D-Pantothenate)
100 mg 70
Choline (Choline Dihydrogen Citrate)
50 mg 55
Inositol
25 mg
Gluten Free Adults 18–50 Vegan Dairy Free Sugar Free Vegetarian
Report overview
A+ Ingredient Form & Label QualityC Dose, Safety & Label TransparencyB+ Value
Each serving provides 25 mg of vitamin B6 from pyridoxal 5-phosphate, a high amount that the evaluation treats cautiously for safety. The whole-product serving costs about $0.35, which is low when compared by its B6 amount.
How this ingredient is rated

Ingredient Form & Label Quality100

The vitamin B6 source is identified as pyridoxal 5-phosphate.
Vitamin B6 Form Identification
The vitamin B6 source is identified as pyridoxal 5-phosphate.
Clean Label and Excipient Purity
The evaluation did not flag the additives it checks for.

Dose, Safety & Label Transparency60

The vitamin B6 amount of 25 mg per serving is a high amount that the evaluation treats cautiously for safety.
Vitamin B6 Dose & Safety Policy
A serving contains 25 mg of vitamin B6, a high amount that the evaluation treats cautiously for safety.
Label Transparency
The recorded B6 source is identified as pyridoxal 5-phosphate.

Value83

The whole-product price is low relative to its vitamin B6 amount.
Vitamin B6 Price Efficiency
The whole-product serving costs about $0.35 and supplies 25 mg of vitamin B6.
B- Active Ingredient Quality & BioavailabilityB- Dose, Safety & Label TransparencyD- Value
Each serving provides 30 mg of thiamin from benfotiamine and thiamine hydrochloride. The individual source proportions are not established in the available facts.
How this ingredient is rated

Active Ingredient Quality & Bioavailability74

The identified sources are benfotiamine and thiamine hydrochloride; their proportions are not established.
Thiamin Chemical Form
Thiamin comes from benfotiamine and thiamine hydrochloride, with their individual proportions unknown.
Excipient Purity
The available other-ingredient information has no corn syrup, selected artificial sweeteners, titanium dioxide or artificial colors flagged by the evaluation.

Dose, Safety & Label Transparency72

Each serving provides 30 mg of thiamin. Both sources are named, but their separate shares are unclear.
Thiamin Dosage Potency
Each serving provides 30 mg of thiamin. That amount fits the evaluated moderate category.
Label Transparency & Proprietary Blends
The 30 mg total and both sources are identified, but their individual proportions are not established.

Value40

Based on the whole-product price, the cost is about $1.16 per 100 mg of thiamin; the price covers the entire product.
Price per Declared Dose
Based on the whole-product price, the cost is about $1.16 per 100 mg of thiamin; the price covers the entire product.
C- Active Ingredient Quality & BioavailabilityC+ Dose, Safety & Label TransparencyC Value
Each serving provides 100 mg of niacin from inositol hexanicotinate. The cost is about $0.35 per whole-product serving.
How this ingredient is rated

Active Ingredient Quality & Bioavailability57

Inositol hexanicotinate is the named niacin form.
Niacin Form & Goal Alignment
Inositol hexanicotinate is the named form; the product also states a skin-support goal.
Precursor Source Quality
The source is inositol hexanicotinate; no branded advanced precursor is identified in the saved facts.

Dose, Safety & Label Transparency67

The saved facts give 100 mg of niacin per serving and identify its form.
Clarity of Chemical Form
The saved facts identify the niacin source as inositol hexanicotinate.
Form-Specific Dosage Efficacy
The serving contains 100 mg of niacin.
Flush Risk & Safety Labeling
Inositol hexanicotinate is generally considered non-flushing; no explicit no-flush claim is recorded in the saved facts.

Value60

The price is about $0.35 per whole-product serving.
Price Per Effective Serving
The price is about $0.35 per whole-product serving.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Physicochemical properties of and volatile compounds in riboflavin fortified cloudy apple juice; study of its effect on job fatigue among Egyptian construction workers.
    Fouad S; Ibrahim GE; Hussein AMS; Ibrahim FA; El Gendy A · Heliyon · 2021
    Non-randomized trialEnergy forRiboflavin
  2. Vitamin B status in patients with chronic fatigue syndrome.
    Heap LC; Peters TJ; Wessely S · Journal of the Royal Society of Medicine · 1999
    Case-control study30 participantsEnergy forRiboflavin
  3. B-vitamins, related vitamers, and metabolites in patients with quiescent inflammatory bowel disease and chronic fatigue treated with high dose oral thiamine.
    Bager P; Hvas CL; Hansen MM; Ueland P; Dahlerup JF · Molecular medicine (Cambridge, Mass.) · 2023
    Observational studyEnergy forRiboflavin
  4. Metabolic features of chronic fatigue syndrome.
    Naviaux RK; Naviaux JC; Li K; Bright AT; Alaynick WA; Wang L; Baxter A; Nathan N; Anderson W; Gordon E · Proceedings of the National Academy of Sciences of the United States of America · 2024
    Case-control study84 participantsEnergy forRiboflavin
  5. Effectiveness of Riboflavin in Inherited Metabolic Diseases: A Systematic Review
    Bregje Jaeger, Nina N Stolwijk, Femke Aaldering, Charlotte A Ruys, Marije Smits, Nicole I Wolf, Carla E M Hollak, Annet M Bosch · Journal of Inherited Metabolic Disease · 2026
    Systematic review381 studies pooledEnergy Metabolism Support forRiboflavin
  6. Influence of thiamin supplementation on the health and general well-being of an elderly Irish population with marginal thiamin deficiency.
    Smidt LJ; Cremin FM; Grivetti LE; Clifford AJ · Journal of gerontology · 1991
    Randomized trial80 participantsEnergy forThiamin
  7. Randomised clinical trial: high-dose oral thiamine versus placebo for chronic fatigue in patients with quiescent inflammatory bowel disease.
    Bager P; Hvas CL; Rud CL; Dahlerup JF · Alimentary pharmacology & therapeutics · 2021
    Randomized trial40 participantsEnergy forThiamin
  8. Dietary reference values for thiamin.
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA); Turck D; Bresson JL; Burlingame B; Dean T; Fairweather-Tait S; Heinonen M; Hirsch-Ernst KI; Mangelsdorf I; McArdle HJ; Naska A; Nowicka G; Pentieva K; Sanz Y; Siani A; Sjödin A; Stern M; Tomé D; Van Loveren H; Vinceti M; Willatts P; Lamberg-Allardt C; Przyrembel H; Tetens I; Gudelj Rakic J; Ioannidou S; de Sesmaisons-Lecarré A; Forss AC; Neuhäuser-Berthold M · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusEnergy forThiamin
  9. Effects of thiamine supplementation on exercise-induced fatigue.
    Suzuki M; Itokawa Y · Metabolic brain disease · 1996
    Randomized trial16 participantsEnergy forThiamin
  10. Long-term maintenance treatment with 300 mg thiamine for fatigue in patients with inflammatory bowel disease: results from an open-label extension of the TARIF study.
    Bager P; Hvas CL; Rud CL; Dahlerup JF · Scandinavian journal of gastroenterology · 2022
    Randomized trialEnergy forThiamin
  11. A new perspective on vitamin B12 deficiency in rheumatology: a case-based review.
    Dułak NA; Rytlewska M; Jaskólska M; Chmielewski M · Rheumatology international · 2024
    Case series3 participantsEnergy forVitamin B12
  12. Effects of Vitamin B12 Supplementation on Cognitive Function, Depressive Symptoms, and Fatigue: A Systematic Review, Meta-Analysis, and Meta-Regression.
    Markun S; Gravestock I; Jäger L; Rosemann T; Pichierri G; Burgstaller JM · Nutrients · 2021
    Meta-analysis6,276 participants16 studies pooledEnergy forVitamin B12
  13. Patients' experiences with methylcobalamin injections in amyotrophic lateral sclerosis.
    Zubair AS; Saab L; Scharer K; Khokhar B · Brain circulation · 2024
    Qualitative study5 participantsEnergy forVitamin B12
  14. Cobalamin deficiency: clinical picture and radiological findings.
    Briani C; Dalla Torre C; Citton V; Manara R; Pompanin S; Binotto G; Adami F · Nutrients · 2014
    Narrative reviewEnergy forVitamin B12
  15. Vitamin B12 Deficiency: Common Questions and Answers.
    Patel H; McGuirk R · American family physician · 2025
    Narrative reviewEnergy forVitamin B12
  16. Intakes of Folate, Vitamin B6, and Vitamin B12 in Relation to All-Cause and Cause-Specific Mortality: A National Population-Based Cohort.
    Bo Y; Xu H; Zhang H; Zhang J; Wan Z; Zhao X; Yu Z · Nutrients · 2022
    Cohort study55,569 participantsEveryday Health forFolate
  17. The responsiveness of plasma homocysteine to small increases in dietary folic acid: a primary care study.
    Schorah CJ; Devitt H; Lucock M; Dowell AC · European journal of clinical nutrition · 1998
    Randomized trial119 participantsEveryday Health forFolate
  18. Associations of Serum Folate and Homocysteine Concentrations with All-Cause, Cardiovascular Disease, and Cancer Mortality in Men and Women in Korea: the Cardiovascular Disease Association Study.
    Song S; Song BM; Park HY · The Journal of nutrition · 2023
    Cohort study21,260 participantsEveryday Health forFolate
  19. The concept of folic acid supplementation and its role in prevention of neural tube defect among pregnant women: PRISMA.
    Seyoum Tola F · Medicine · 2024
    Systematic reviewEveryday Health forFolate
  20. Systematic review of adverse health outcomes associated with high serum or red blood cell folate concentrations.
    Colapinto CK; O'Connor DL; Sampson M; Williams B; Tremblay MS · Journal of public health (Oxford, England) · 2017
    Systematic review71,847 participants46 studies pooledEveryday Health forFolate