Advanced B Complex

Advanced B Complex

Format:Capsule Quantity: 90 Capsule(s) · 90 servings
Goals

Product analysis

60 out of 100

Advanced B Complex supplies nutrients involved in normal energy use and blood formation. Conflicting declarations for several B-vitamin amounts make it harder to judge what a serving provides.

AI assessment of the formula, label and price. How scoring works

Nutrient Quality55

Several B-vitamin forms are clearly identified, but the niacin description does not specify its chemical form. Other quality conclusions remain uncertain, and the shares within mixed B5 sources are undisclosed.

Ingredient Transparency77

Amounts are listed, but conflicting declarations for several B vitamins make the serving less clear. Most forms are named, while the shares within the B5 and inositol mixtures remain undisclosed.

Value For Money34

Vitamin B6 compares favourably on cost, while niacin, B5 and choline compare poorly. Several other value comparisons remain uncertain.

Customer Satisfaction89

Customer ratings are generally positive across a substantial review base. The feedback does not establish effectiveness or safety.

Product Focus51

The main purpose is B-vitamin nutrition that may help when intake is low. Conflicting declarations for several amounts limit expectations, and additional energy or mood benefits above adequate nutrition remain uncertain.

Format
Capsule
Container
90 Capsule(s)
Per serving
$0.34
Customer rating
4.8 · 3,090 ratings
Report analysis

Goals

Impact
Moderate effect
C- Ingredient FitF PathwaysB EvidenceA- Formulation Logic
Vitamin B5 · 100 mgRiboflavin · 2.5 mgThiamin · 33 mgVitamin B12 · 333 mcg

Pantothenic acid, riboflavin and folate support normal nutritional functions related to energy and tiredness. Several other B-vitamin amounts conflict in the supplied panel, limiting their assessment. Higher vitamin amounts do not establish extra energy once needs are met.

How this product is rated for Energy

Ingredient fit58

Focus share 87.5 from 7 credited ingredients and 2 off-goal actives (Choline, Inositol); link focus 55.0 from 8 linked goals. Goal focus = 70% × share + 30% × link focus The saved amount assessment is limited; unresolved individual amounts limit the assessed contribution.
Goal fit
Focus share 87.5 from 7 credited ingredients and 2 off-goal actives (Choline, Inositol); link focus 55.0 from 8 linked goals. Goal focus = 70% × share + 30% × link focus
Dose adequacy
The saved amount assessment is limited; unresolved individual amounts limit the assessed contribution.

Pathways0

No assessed energy pathway has meaningful coverage. 0 of 3 target areas meet the saved coverage threshold.
Depth
No assessed energy pathway has meaningful coverage.
Breadth
0 of 3 target areas meet the saved coverage threshold.

Evidence78

Vitamin B2 (Riboflavin) is the strongest evidence contributor at an eligible amount in the saved findings. The eligible ingredients match preparations accepted in the saved assessment.
Evidence strength
Vitamin B2 (Riboflavin) is the strongest evidence contributor at an eligible amount in the saved findings.
Studied preparation
The eligible ingredients match preparations accepted in the saved assessment.

Formulation logic86

The assessed ingredients can contribute alone or have their required partners. No configured ingredient conflicts were identified in the supplied facts. 3 of 7 assessed ingredients meet the saved minimum amount threshold; below it: Vitamin B1 (Thiamin), Vitamin B12, Vitamin B6, Niacin.
Partner coverage
The assessed ingredients can contribute alone or have their required partners.
Conflicts
No configured ingredient conflicts were identified in the supplied facts.
Effective doses
3 of 7 assessed ingredients meet the saved minimum amount threshold; below it: Vitamin B1 (Thiamin), Vitamin B12, Vitamin B6, Niacin.
Study evidence
Thiamin Disputed 12 studies
Impact
Moderate effect
D+ Ingredient FitF PathwaysA+ EvidenceB+ Formulation Logic
Biotin · 167 mcgNiacin · 118 mgVitamin B12 · 333 mcgRiboflavin · 2.5 mgThiamin · 33 mgVitamin B5 · 100 mgVitamin B6 · 33 mg

B vitamins help your body use energy from food, with thiamin playing a part in normal carbohydrate metabolism. That everyday role doesn't mean taking extra will make you burn more calories when you already get enough. The nutrients here relate mainly to normal metabolic function; a lasting rise in energy expenditure or weight loss remains uncertain. Conflicting declarations leave several B-vitamin amounts unresolved.

How this product is rated for Metabolism Support

Ingredient fit54

The B vitamins help normal energy metabolism; extra intake is not known to increase calorie burning.
Goal fit
The B vitamins help normal energy metabolism; extra intake is not known to increase calorie burning.
Dose adequacy
Vitamin B5 is declared at 100 mg and riboflavin at 2.5 mg; conflicting declarations leave five other B-vitamin amounts unresolved.

Pathways0

Normal nutrient-dependent metabolism is distinct from directly increasing whole-body energy expenditure.
Depth
Normal nutrient-dependent metabolism is distinct from directly increasing whole-body energy expenditure.
Breadth
No direct calorie-burning mechanism is identified for these nutrient roles.

Evidence96

The B vitamins help normal energy metabolism; extra intake is not known to increase calorie burning.
Evidence strength
The B vitamins help normal energy metabolism; extra intake is not known to increase calorie burning.
Studied preparation
The declared ingredient forms match the relevant preparation descriptions; this alone does not predict the size of a benefit.

Formulation logic82

No particular ingredient conflict or missing required partner is identified.
Partner coverage
No required companion ingredient is missing for the ingredient roles described here.
Conflicts
No particular ingredient conflict is identified.
Effective doses
Vitamin B5 is declared at 100 mg and riboflavin at 2.5 mg; conflicting declarations leave five other B-vitamin amounts unresolved.
Study evidence
Biotin Supportive 5 studies
Niacin Supportive 17 studies
Thiamin Supportive 11 studies
Vitamin B6 Supportive 16 studies

Ingredients

IngredientAmount per servingScore
Thiamine (Benfotiamine)
33 mg 73
Riboflavin (Riboflavin 5-Phosphate Sodium)
2.5 mg
Niacin (Vitamin B3)
118 mg 33
Vitamin B6 (Pyridoxal 5-Phosphate)
33 mg 79
Folate (Calcium L-5-Methyltetrahydrofolate)
555 mcg DFE
Vitamin B12 (Methylcobalamin)
333 mcg 67
Biotin
167 mcg
Pantothenic Acid (Calcium D-Pantothenate, Pantethine, Vitamin B5)
100 mg 70
Choline (Choline Bitartrate)
80 mg 55
Inositol (Inositol Hexanicotinate)
131 mg
Gluten Free Adults 18–50 Vegan Dairy Free Vegetarian
Report overview
A+ Ingredient Form & Label QualityD+ Dose, Safety & Label TransparencyA Value
Each serving contains 33 mg of vitamin B6, exceeding the European adult daily upper limit. The source is pyridoxal 5-phosphate; B6 from food or other supplements also adds to total intake.
How this ingredient is rated

Ingredient Form & Label Quality100

Vitamin B6 is supplied as pyridoxal 5-phosphate. No artificial colors, titanium dioxide or talc are flagged in the saved evaluation; other excipients may still be present.
Vitamin B6 Form Identification
The identified vitamin B6 source is pyridoxal 5-phosphate.
Clean Label and Excipient Purity
No artificial colors, titanium dioxide or talc are flagged in the saved evaluation; other excipients may still be present.

Dose, Safety & Label Transparency53

A serving contains 33 mg of vitamin B6. One serving exceeds the European adult daily upper limit for B6; intake from food and other supplements also counts.
Vitamin B6 Dose & Safety Policy
A serving contains 33 mg of B6. One serving exceeds the European adult daily upper limit for B6; intake from food and other supplements also counts.
Label Transparency
The saved facts identify pyridoxal 5-phosphate as the vitamin B6 source.

Value90

At the whole-product price, the equivalent cost is about 1.04 cents per mg of vitamin B6.
Vitamin B6 Price Efficiency
At the whole-product price, the equivalent cost is about 1.04 cents per mg of vitamin B6.
A Active Ingredient Quality & BioavailabilityB- Dose, Safety & Label TransparencyD- Value
A serving provides 33 mg of thiamin from benfotiamine, a fat-soluble form. The whole-product price is about $1.04 per 100 mg of thiamin.
How this ingredient is rated

Active Ingredient Quality & Bioavailability91

Benfotiamine is the recorded fat-soluble source. No evaluated additives were flagged in the available other-ingredient information.
Thiamin Chemical Form
Benfotiamine is the recorded fat-soluble thiamin source.
Excipient Purity
The available other-ingredient information did not flag the evaluated sweeteners, titanium dioxide or artificial colors.

Dose, Safety & Label Transparency72

A serving provides 33 mg of thiamin. The source form is recorded.
Thiamin Dosage Potency
A serving provides 33 mg of thiamin.
Label Transparency & Proprietary Blends
The saved facts record the thiamin amount per serving.

Value40

Based on the recorded thiamin amount, the whole-product price is about $1.04 per 100 mg of thiamin.
Price per Declared Dose
Based on the recorded thiamin amount, the whole-product price is about $1.04 per 100 mg of thiamin.
A Active Ingredient Quality & BioavailabilityB- Dose, Safety & Label TransparencyF Value
Each serving lists 100 mg of vitamin B5 from calcium D-pantothenate and pantethine, but their proportions are not disclosed. The whole product costs about $1.71 per 500 mg of B5, which is expensive on this ingredient measure.
How this ingredient is rated

Active Ingredient Quality & Bioavailability92

Calcium D-pantothenate and pantethine are named B5 forms, but their individual proportions are not disclosed.
Vitamin B5 Chemical Form
The label names calcium D-pantothenate and pantethine without stating how much comes from each form.

Dose, Safety & Label Transparency74

The label lists 100 mg of B5 per serving and names both sources, without separating their amounts.
Dosage Potency and Efficacy
Each serving supplies 100 mg of vitamin B5.
Label Transparency & Source Clarity
The label names both forms and gives the total B5 amount, but not their individual proportions.

Value20

At about $1.71 per 500 mg of B5, the price reflects the whole product and its other ingredients.
Price per 500mg Vitamin B5
The whole product costs about $1.71 per 500 mg of B5, placing it in the higher-cost category for this comparison.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Physicochemical properties of and volatile compounds in riboflavin fortified cloudy apple juice; study of its effect on job fatigue among Egyptian construction workers.
    Fouad S; Ibrahim GE; Hussein AMS; Ibrahim FA; El Gendy A · Heliyon · 2021
    Non-randomized trialEnergy forRiboflavin
  2. Vitamin B status in patients with chronic fatigue syndrome.
    Heap LC; Peters TJ; Wessely S · Journal of the Royal Society of Medicine · 1999
    Case-control study30 participantsEnergy forRiboflavin
  3. B-vitamins, related vitamers, and metabolites in patients with quiescent inflammatory bowel disease and chronic fatigue treated with high dose oral thiamine.
    Bager P; Hvas CL; Hansen MM; Ueland P; Dahlerup JF · Molecular medicine (Cambridge, Mass.) · 2023
    Observational studyEnergy forRiboflavin
  4. Metabolic features of chronic fatigue syndrome.
    Naviaux RK; Naviaux JC; Li K; Bright AT; Alaynick WA; Wang L; Baxter A; Nathan N; Anderson W; Gordon E · Proceedings of the National Academy of Sciences of the United States of America · 2024
    Case-control study84 participantsEnergy forRiboflavin
  5. Effectiveness of Riboflavin in Inherited Metabolic Diseases: A Systematic Review
    Bregje Jaeger, Nina N Stolwijk, Femke Aaldering, Charlotte A Ruys, Marije Smits, Nicole I Wolf, Carla E M Hollak, Annet M Bosch · Journal of Inherited Metabolic Disease · 2026
    Systematic review381 studies pooledEnergy Metabolism Support forRiboflavin
  6. Influence of thiamin supplementation on the health and general well-being of an elderly Irish population with marginal thiamin deficiency.
    Smidt LJ; Cremin FM; Grivetti LE; Clifford AJ · Journal of gerontology · 1991
    Randomized trial80 participantsEnergy forThiamin
  7. Randomised clinical trial: high-dose oral thiamine versus placebo for chronic fatigue in patients with quiescent inflammatory bowel disease.
    Bager P; Hvas CL; Rud CL; Dahlerup JF · Alimentary pharmacology & therapeutics · 2021
    Randomized trial40 participantsEnergy forThiamin
  8. Dietary reference values for thiamin.
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA); Turck D; Bresson JL; Burlingame B; Dean T; Fairweather-Tait S; Heinonen M; Hirsch-Ernst KI; Mangelsdorf I; McArdle HJ; Naska A; Nowicka G; Pentieva K; Sanz Y; Siani A; Sjödin A; Stern M; Tomé D; Van Loveren H; Vinceti M; Willatts P; Lamberg-Allardt C; Przyrembel H; Tetens I; Gudelj Rakic J; Ioannidou S; de Sesmaisons-Lecarré A; Forss AC; Neuhäuser-Berthold M · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusEnergy forThiamin
  9. Effects of thiamine supplementation on exercise-induced fatigue.
    Suzuki M; Itokawa Y · Metabolic brain disease · 1996
    Randomized trial16 participantsEnergy forThiamin
  10. Long-term maintenance treatment with 300 mg thiamine for fatigue in patients with inflammatory bowel disease: results from an open-label extension of the TARIF study.
    Bager P; Hvas CL; Rud CL; Dahlerup JF · Scandinavian journal of gastroenterology · 2022
    Randomized trialEnergy forThiamin
  11. A new perspective on vitamin B12 deficiency in rheumatology: a case-based review.
    Dułak NA; Rytlewska M; Jaskólska M; Chmielewski M · Rheumatology international · 2024
    Case series3 participantsEnergy forVitamin B12
  12. Effects of Vitamin B12 Supplementation on Cognitive Function, Depressive Symptoms, and Fatigue: A Systematic Review, Meta-Analysis, and Meta-Regression.
    Markun S; Gravestock I; Jäger L; Rosemann T; Pichierri G; Burgstaller JM · Nutrients · 2021
    Meta-analysis6,276 participants16 studies pooledEnergy forVitamin B12
  13. Patients' experiences with methylcobalamin injections in amyotrophic lateral sclerosis.
    Zubair AS; Saab L; Scharer K; Khokhar B · Brain circulation · 2024
    Qualitative study5 participantsEnergy forVitamin B12
  14. Cobalamin deficiency: clinical picture and radiological findings.
    Briani C; Dalla Torre C; Citton V; Manara R; Pompanin S; Binotto G; Adami F · Nutrients · 2014
    Narrative reviewEnergy forVitamin B12
  15. Vitamin B12 Deficiency: Common Questions and Answers.
    Patel H; McGuirk R · American family physician · 2025
    Narrative reviewEnergy forVitamin B12
  16. Biotin and contribution to normal energy-yielding metabolism: evaluation of a health claim pursuant to Article 14 of Regulation (EC) No 1924/2006.
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusMetabolism Support forBiotin
  17. Pregnancy and lactation alter biomarkers of biotin metabolism in women consuming a controlled diet.
    Perry CA; West AA; Gayle A; Lucas LK; Yan J; Jiang X; Malysheva O; Caudill MA · The Journal of nutrition · 2015
    Clinical trial75 participantsMetabolism Support forBiotin
  18. Survey of the effect of biotin on glycemic control and plasma lipid concentrations in type 1 diabetic patients in kermanshah in iran (2008-2009)
    Hemmati M, Babaei H, Abdolsalehei M · Oman Medical Journal · 2013
    Randomized trial70 participantsMetabolism Support forBiotin
  19. Chromium picolinate and biotin combination improves glucose metabolism in treated, uncontrolled overweight to obese patients with type 2 diabetes
    César A Albarracin, Bobby C Fuqua, James L Evans, Ira D Goldfine · Diabetes/Metabolism Research and Reviews · 2008
    Randomized trial348 participantsMetabolism Support forBiotin
  20. Biotin supplementation reduces plasma triacylglycerol and VLDL in type 2 diabetic patients and in nondiabetic subjects with hypertriglyceridemia
    Cristina Revilla-Monsalve, Iván Zendejas-Ruiz, Sergio Islas-Andrade, Armida Báez-Saldaña, Miguel Angel Palomino-Garibay, Pedro Martín Hernández-Quiróz, Cristina Fernandez-Mejia · Biomedicine & Pharmacotherapy · 2006
    Randomized trial33 participantsMetabolism Support forBiotin