Adrenal Assist

Adrenal Assist

Vitanica4.6 (667 ratings)
Format:Capsule Quantity: 90 Capsule(s) · 30 servings
Goals

Product analysis

55 out of 100

Adrenal Assist supplies vitamins and minerals to help fill dietary gaps, with herbs that may help stress-related fatigue. The unspecified herbal preparations make their benefits harder to predict.

AI assessment of the formula, label and price. How scoring works

Nutrient Quality43

The B6 form is clearly identified, and B5 uses a favorable form. Several other ingredients cannot be judged confidently, with most herbal preparations left unspecified.

Ingredient Transparency79

Amounts are disclosed, making the serving easier to compare. Many forms are omitted, especially among the herbs, so the preparations are less clearly described.

Value For Money37

B6 offers reasonably favorable value, but vitamin C, B5 and several herbs are expensive for the amounts supplied. Value for much of the remaining mixture is uncertain.

Customer Satisfaction77

Customer ratings are very positive across a substantial amount of feedback. The review volume gives a broader satisfaction picture without proving a stress or fatigue benefit.

Product Focus49

The clearest benefits involve filling nutritional gaps, with possible stress-related help from selected herbs. Their effects depend on the preparation and amount, so the broad mixture does not establish reliable mood, focus or productivity improvements.

Format
Capsule
Container
90 Capsule(s)
Per serving
$1.05
Customer rating
4.6 · 667 ratings
Report analysis

Goals

Energy
Impact
Lower effect
B- Ingredient FitF PathwaysD- EvidenceA+ Formulation Logic
Vitamin B5 · 100 mgMagnesium · 50 mg
Study evidence
Eleuthero Disputed 3 studies
Magnesium Supportive 4 studies
Rhodiola Supportive 18 studies
Mood Support
Impact
High effect
C Ingredient FitC PathwaysA+ EvidenceA+ Formulation Logic
Vitamin B6 · 50 mgMagnesium · 50 mgAshwagandha · 100 mg

Vitamin B6 supports normal mood when deficiency disrupts its functions. Ashwagandha may support stress-associated emotional well-being, but this small amount of an unidentified extract has limited applicability to trials of named extracts. Rhodiola findings chiefly concern fatigue or clinical depression rather than routine mood improvement. Zinc findings also come mainly from diagnosed depression alongside medication; the small magnesium amount contributes little to the saved findings.

How this product is rated for Mood Support

Ingredient fit61

The mood-related contribution comes from the relevant ingredients at their declared serving amounts, with the ingredient-specific limits described above.
Goal fit
The contributing ingredients address mood-related roles within a broader formula containing ingredients intended for other purposes.
Dose adequacy
Amounts vary in their contribution; Ashwagandha and Magnesium fall below the saved contribution threshold.

Pathways60

The ingredients represent the areas described below; these are ingredient relationships rather than proof that every mechanism produces a mood benefit.
Depth
The strongest represented area is monoamine signalling, reflecting the ingredients and amounts retained in the saved findings.
Breadth
The saved findings cover monoamine signalling.

Evidence96

The retained evidence and preparation findings below must be interpreted alongside each ingredient’s direct mood outcomes and the populations studied.
Evidence strength
Vitamin B6 provides the strongest retained evidence contribution, with the population and outcome limits described for that ingredient.
Studied preparation
The retained preparations meet the saved matching check; this does not remove the population or outcome limits of their supporting findings.

Formulation logic100

The supplied partner, conflict and minimum-amount checks are satisfied for the retained contributors, without establishing synergy or medication suitability.
Partner coverage
No contributing ingredient is missing a required partner in the supplied checks; this does not establish added benefit from combining ingredients.
Conflicts
No listed ingredient conflict was triggered by the supplied product facts; this check does not establish general medication compatibility.
Effective doses
All retained contributors meet the saved minimum amount threshold; that threshold is not a proven effective dose for improving mood.
Study evidence
Magnesium Supportive 60 studies
Rhodiola Supportive 15 studies
Vitamin B6 Supportive 19 studies
Zinc Supportive 43 studies
Brain Health
Impact
High effect
D+ Ingredient FitC PathwaysA EvidenceA+ Formulation Logic
Vitamin B6 · 50 mgMagnesium · 50 mgAshwagandha · 100 mg

B6 and zinc support normal nutritional function, without established extra cognitive benefit when intake is adequate. Rhodiola has findings in stress-related fatigue, but these depend on the studied preparation and population. The small magnesium and ashwagandha amounts did not contribute to the saved comparison, and their presence does not establish cognitive improvement.

How this product is rated for Brain Health

Ingredient fit55

Amounts give a mixed or partial overall finding. Small magnesium and ashwagandha amounts were excluded.
Goal fit
Relevant ingredients contribute, but the broader formula and its links to other goals reduce its focus on brain health.
Dose adequacy
The declared relevant amounts receive partial overall allowance; this reflects the saved comparison rather than a proven benefit threshold.

Pathways60

The saved findings concentrate on nutrient involvement in neurotransmitter production. This does not demonstrate broad cognitive effects.
Depth
The strongest saved finding concerns nutrient involvement in neurotransmitter production, reaching the comparison's coverage target.
Breadth
Only nutrient involvement in neurotransmitter production reaches the saved breadth threshold, so coverage remains concentrated.

Evidence92

Vitamin B6 is the strongest contributor to the saved evidence finding. The practical support is chiefly nutritional, with no established extra cognitive benefit from adequate intake.
Evidence strength
Vitamin B6 leads the saved evidence finding. Nutritional necessity does not establish extra cognitive improvement.
Studied preparation
Qualifying ingredients meet the saved preparation criteria; this does not remove the population and preparation limitations in the supplied science.

Formulation logic100

The saved findings show no unmet partner or matched conflict. Amount thresholds describe the comparison and do not establish combination benefits.
Partner coverage
The relevant ingredients have no unmet required partner in the saved findings; this does not demonstrate added benefit from combining them.
Conflicts
No configured conflict was matched. The caffeine amount penalties were inapplicable; this is not a general safety finding.
Effective doses
All ingredients included in this rule meet its saved amount threshold; that threshold is not a proven effective dose.
Study evidence
Magnesium Supportive 86 studies
Rhodiola Supportive 8 studies
Vitamin B6 Supportive 29 studies
Zinc Supportive 38 studies
Stress Relief
Impact
High effect
C Ingredient FitB+ PathwaysC+ EvidenceA+ Formulation Logic
Ashwagandha · 100 mgMagnesium · 50 mgVitamin B6 · 50 mgVitamin C · 500 mgEleuthero · 50 mg

Ashwagandha and rhodiola may help with perceived stress and stress-related fatigue, but their effects depend on extract identity and repeated-use findings. Holy basil has extract-specific stress evidence; this declaration did not match a studied preparation. Vitamin C has some subjective stress findings, while B6, B5 and zinc provide more conditional or indirect support. Several amounts provide only partial contributions, and the small magnesium and eleuthero amounts were not counted.

How this product is rated for Stress Relief

Ingredient fit63

Stress-related ingredients are part of a broader formula with ingredients serving other needs. The disclosed amounts provide partial coverage of the saved references, limiting how strongly the formula matches those amount expectations.
Goal fit
Stress-related ingredients are part of a broader formula with ingredients serving other needs.
Dose adequacy
The disclosed amounts provide partial coverage of the saved references, limiting how strongly the formula matches those amount expectations.

Pathways80

The strongest saved finding concerns stress-hormone regulation, rather than equal support across every aspect of stress. The saved findings cover stress-hormone regulation, mood and neurotransmitter synthesis. These ingredient roles do not establish distinct clinical benefits.
Depth
The strongest saved finding concerns stress-hormone regulation, rather than equal support across every aspect of stress.
Breadth
The saved findings cover stress-hormone regulation, mood and neurotransmitter synthesis. These ingredient roles do not establish distinct clinical benefits.

Evidence70

Ashwagandha provides the strongest supplied support here; study populations, preparations and outcomes limit how broadly relief can be expected.
Evidence strength
Ashwagandha provides the strongest supplied support here; study populations, preparations and outcomes limit how broadly relief can be expected.
Studied preparation
Ashwagandha and holy basil did not meet the saved studied-preparation finding; their effects cannot be assumed equivalent to identified trial extracts.

Formulation logic96

B6 and B5 lack their configured B-vitamin partners, reducing the saved combination finding. No specified ingredient conflict was identified in the saved findings.
Partner coverage
B6 and B5 lack their configured B-vitamin partners, reducing the saved combination finding.
Conflicts
No specified ingredient conflict was identified in the saved findings.
Effective doses
All counted ingredients meet the saved minimum amount criterion; this does not establish independent stress relief from each ingredient.
Study evidence
Magnesium Supportive 13 studies
Rhodiola Supportive 16 studies
Vitamin C Supportive 11 studies
Zinc Supportive 9 studies
Mental Focus
Impact
Moderate effect
C Ingredient FitF PathwaysD- EvidenceA+ Formulation Logic
Vitamin B6 · 50 mgMagnesium · 50 mg

Rhodiola at 200 mg provides the main assessed connection to stress and fatigue, with smaller amounts of eleuthero and ashwagandha alongside it. The evidence depends on particular extracts and study conditions, so those findings cannot be freely transferred between preparations. B6, zinc and magnesium add normal nutrient support.

How this product is rated for Mental Focus

Ingredient fit62

The blend serves broader purposes, with only part of its assessed ingredients directed at focus. The counted amounts broadly support the supplied comparison ranges, although support varies by ingredient.
Goal fit
The blend serves broader purposes, with only part of its assessed ingredients directed at focus.
Dose adequacy
The counted amounts broadly support the supplied comparison ranges, although support varies by ingredient.

Pathways15

The strongest assessed connection is stress and fatigue resilience, with limited coverage. No mechanism reaches the saved broader-coverage threshold.
Depth
The strongest assessed connection is stress and fatigue resilience, with limited coverage.
Breadth
No mechanism reaches the saved broader-coverage threshold.

Evidence42

Rhodiola provides the strongest relevant evidence among ingredients counted at meaningful amounts. The findings remain specific to the reviewed context. Only part of the assessed contribution matches preparations accepted in the reviewed evidence.
Evidence strength
Rhodiola provides the strongest relevant evidence among ingredients counted at meaningful amounts. The findings remain specific to the reviewed context.
Studied preparation
Only part of the assessed contribution matches preparations accepted in the reviewed evidence.

Formulation logic100

The counted ingredients can contribute independently or have their required partner. No ingredient conflict was identified in the saved assessment. 3 of 3 counted ingredients reach the saved meaningful-amount threshold.
Partner coverage
The counted ingredients can contribute independently or have their required partner.
Conflicts
No ingredient conflict was identified in the saved assessment.
Effective doses
3 of 3 counted ingredients reach the saved meaningful-amount threshold.
Study evidence
Eleuthero Disputed 3 studies
Magnesium Supportive 6 studies
Rhodiola Supportive 15 studies
Zinc Mixed 16 studies
Cognitive Support
Impact
Moderate effect
C Ingredient FitF PathwaysA EvidenceA+ Formulation Logic
Vitamin B6 · 50 mgMagnesium · 50 mgAshwagandha · 100 mg

Rhodiola relates to mental performance during stress and fatigue, but the 200 mg material is not confirmed as the studied preparation. Ashwagandha findings also depend on the extract used; B6 supports neurotransmitter metabolism, without establishing routine cognitive enhancement.

How this product is rated for Cognitive Support

Ingredient fit61

Some ingredients relate to cognitive support, within a broader mix serving several purposes. The assessed amounts partly align with the saved ingredient comparisons, with uneven coverage.
Goal fit
Some ingredients relate to cognitive support, within a broader mix serving several purposes.
Dose adequacy
The assessed amounts partly align with the saved ingredient comparisons, with uneven coverage.

Pathways11

The saved findings identify limited coverage related to stress and arousal regulation. No reviewed mechanism reaches the saved coverage threshold.
Depth
The saved findings identify limited coverage related to stress and arousal regulation.
Breadth
No reviewed mechanism reaches the saved coverage threshold.

Evidence92

Vitamin B6 provides the strongest saved ingredient finding; its normal metabolic role does not imply broad cognitive enhancement. Most qualifying preparations match the saved comparisons, while rhodiola is not identified as the studied preparation.
Evidence strength
Vitamin B6 provides the strongest saved ingredient finding; its normal metabolic role does not imply broad cognitive enhancement.
Studied preparation
Most qualifying preparations match the saved comparisons, while rhodiola is not identified as the studied preparation.

Formulation logic100

The saved findings identify no missing required ingredient partner. No configured ingredient conflict was identified in the saved findings. All ingredients assessed for amounts meet the saved minimum comparison level.
Partner coverage
The saved findings identify no missing required ingredient partner.
Conflicts
No configured ingredient conflict was identified in the saved findings.
Effective doses
All ingredients assessed for amounts meet the saved minimum comparison level.
Study evidence
Magnesium Supportive 24 studies
Rhodiola Supportive 7 studies
Vitamin B6 Supportive 17 studies
Zinc Supportive 48 studies

Ingredients

IngredientAmount per servingScore
Vitamin C (Calcium Ascorbate)
500 mg 73
Vitamin B6 (Pyridoxal 5-Phosphate)
50 mg 69
Vitamin B5 (Calcium Pantothenate)
100 mg 70
Calcium (Calcium Pantothenate)
57 mg
Magnesium (Magnesium Bisglycinate Chelate)
50 mg
Zinc (Zinc Bisglycinate Chelate)
10 mg
Rhodiola rosea root extract
200 mg 63
Astragalus
150 mg 100
Maca
125 mg
Ashwagandha root extract
100 mg 65
Holy Basil leaf extract
100 mg
American Ginseng root extract
100 mg
Schizandra
75 mg
Eleutherococcus senticosus root extract
50 mg 70
Gluten Free Adults 18–50 Vegan Dairy Free Sugar Free Women Vegetarian
Report overview
A+ Ingredient Form & Label QualityF Dose, Safety & Label TransparencyB- Value
Each serving provides 50 mg of vitamin B6, a relatively large amount, at a moderate cost for that amount. The source is Pyridoxal 5-Phosphate. The listed ingredients do not indicate artificial colors, titanium dioxide, hydrogenated oils or talc.
How this ingredient is rated

Ingredient Form & Label Quality100

The source is Pyridoxal 5-Phosphate. The listed ingredients do not indicate artificial colors, titanium dioxide, hydrogenated oils or talc.
Vitamin B6 Form Identification
The source is Pyridoxal 5-Phosphate.
Clean Label and Excipient Purity
The listed ingredients do not indicate artificial colors, titanium dioxide, hydrogenated oils or talc.

Dose, Safety & Label Transparency37

The label states 50 mg of vitamin B6 per serving and names its source.
Vitamin B6 Dose & Safety Policy
Each serving provides 50 mg of vitamin B6, a relatively large amount.
Label Transparency
The label names Pyridoxal 5-Phosphate as the source.

Value71

The cost is moderate for the amount of vitamin B6.
Vitamin B6 Price Efficiency
The cost is moderate for the amount of vitamin B6.
A Active Ingredient Quality & BioavailabilityB Dose, Safety & Label TransparencyF Value
Each serving supplies 100 mg of vitamin B5, at a high cost for the amount supplied. It uses Calcium Pantothenate, a stable and well-absorbed form.
How this ingredient is rated

Active Ingredient Quality & Bioavailability90

Calcium Pantothenate is a stable, well-absorbed form of vitamin B5.
Vitamin B5 Chemical Form
Calcium Pantothenate is a stable, well-absorbed form of vitamin B5.

Dose, Safety & Label Transparency76

Each serving provides 100 mg of vitamin B5. The label states both the B5 amount and its Calcium Pantothenate source.
Dosage Potency and Efficacy
Each serving provides 100 mg of vitamin B5.
Label Transparency & Source Clarity
The label states both the B5 amount and its Calcium Pantothenate source.

Value20

The cost is high for the amount of vitamin B5 provided.
Price per 500mg Vitamin B5
The cost is high for the amount of vitamin B5 provided.
B+ Active Ingredient Quality & BioavailabilityA Dose, Safety & Label TransparencyF Value
Each serving provides 500 mg of vitamin C as Calcium Ascorbate, at a high cost based on the full serving price. The vitamin C amount is clearly stated.
How this ingredient is rated

Active Ingredient Quality & Bioavailability83

It uses Calcium Ascorbate. The mineral ascorbate form is buffered.
Vitamin C Chemical Form & Delivery System
It uses Calcium Ascorbate.
Gastric Comfort & pH Balance
The mineral ascorbate form is buffered.

Dose, Safety & Label Transparency91

The serving provides 500 mg of vitamin C. No flagged sweeteners or artificial colors are noted in the Other Ingredients.
Optimal Dosage Targeting
Each serving provides 500 mg of vitamin C.
Purity & Excipient Quality
No flagged sweeteners or artificial colors are noted in the Other Ingredients.
Mineral & Source Transparency
The vitamin C amount and 57 mg of calcium are disclosed.

Value20

The cost based on the full serving price is high for the vitamin C supplied; other ingredients may contribute to that price.
Price per Gram of Vitamin C
The cost based on the full serving price is high for the vitamin C supplied; other ingredients may contribute to that price.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Acute and Repeated Ashwagandha Supplementation Improves Markers of Cognitive Function and Mood.
    Leonard M; Dickerson B; Estes L; Gonzalez DE; Jenkins V; Johnson S; Xing D; Yoo C; Ko J; Purpura M; Jäger R; Faries M; Kephart W; Sowinski R; Rasmussen CJ; Kreider RB · Nutrients · 2024
    Randomized trial59 participantsBrain Health Cognitive Support Energy forAshwagandha
  2. Effect of ashwagandha (Withania somnifera) extract with Sominone (Somin-On™) to improve memory in adults with mild cognitive impairment: A randomized, double-blind, placebo-controlled study.
    Rai HP; Mishra DN · Journal of psychopharmacology (Oxford, England) · 2025
    Randomized trial40 participantsBrain Health Cognitive Support Mental Focus forAshwagandha
  3. Efficacy of Withania somnifera supplementation on adult's cognition and mood.
    Remenapp A; Coyle K; Orange T; Lynch T; Hooper D; Hooper S; Conway K; Hausenblas HA · Journal of Ayurveda and integrative medicine · 2022
    Randomized trial60 participantsBrain Health Cognitive Support Productivity Boost forAshwagandha
  4. A clinical assessment of the therapeutic effects of Ashwagandha root extract on cognitive performance, sleep, and fatigue in children aged 6-12 years.
    Saxena A; Lopresti A; Sharif M; Elon N; Suri R; Langade DK · Frontiers in nutrition · 2026
    Randomized trial85 participantsBrain Health Mental Focus forAshwagandha
  5. Efficacy and Safety of Ashwagandha Root Extract on Cognitive Functions in Healthy, Stressed Adults: A Randomized, Double-Blind, Placebo-Controlled Study.
    Gopukumar K; Thanawala S; Somepalli V; Rao TSS; Thamatam VB; Chauhan S · Evidence-based complementary and alternative medicine : eCAM · 2022
    Randomized trial130 participantsBrain Health Stress Relief forAshwagandha
  6. Antenatal magnesium sulfate and neuroprotection.
    Doyle LW · Current opinion in pediatrics · 2012
    Meta-analysis6,145 participants5 studies pooledBrain Health forMagnesium
  7. No. 376-Magnesium Sulphate for Fetal Neuroprotection.
    Magee LA; De Silva DA; Sawchuck D; Synnes A; von Dadelszen P · Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC · 2020
    Guideline / consensus4,446 participantsBrain Health forMagnesium
  8. Magnesium Sulfate Before Preterm Birth for Neuroprotection: An Updated Cochrane Systematic Review.
    Shepherd ES; Goldsmith S; Doyle LW; Middleton P; Marret S; Rouse DJ; Pryde P; Wolf HT; Crowther CA · Obstetrics and gynecology · 2024
    Systematic review5,917 participants6 studies pooledBrain Health forMagnesium
  9. Magnesium sulphate for fetal neuroprotection at imminent risk for preterm delivery: a systematic review with meta-analysis and trial sequential analysis.
    Wolf HT; Huusom LD; Henriksen TB; Hegaard HK; Brok J; Pinborg A · BJOG : an international journal of obstetrics and gynaecology · 2020
    Meta-analysis5,917 participants6 studies pooledBrain Health forMagnesium
  10. Magnesium sulfate and fetal neuroprotection: overview of clinical evidence.
    Chollat C; Marret S · Neural regeneration research · 2020
    Narrative reviewBrain Health forMagnesium
  11. Dose-Response Effects of Short-Term Rhodiola rosea (Golden Root Extract) Supplementation on Anaerobic Exercise Performance and Cognitive Function in Resistance-Trained Athletes: A Randomized, Crossover, Double-Blind, and Placebo-Controlled Study.
    Koozehchian MS; Newton AT; Mabrey G; Bonness FM; Rafajlovska R; Naderi A · Nutrients · 2025
    Randomized trial27 participantsBrain Health Mental Focus forRhodiola
  12. A combination of green tea, rhodiola, magnesium and B vitamins modulates brain activity and protects against the effects of induced social stress in healthy volunteers.
    Boyle NB; Billington J; Lawton C; Quadt F; Dye L · Nutritional neuroscience · 2022
    Randomized trial100 participantsBrain Health forRhodiola
  13. Rosenroot (Rhodiola rosea): traditional use, chemical composition, pharmacology and clinical efficacy.
    Panossian A; Wikman G; Sarris J · Phytomedicine : international journal of phytotherapy and phytopharmacology · 2010
    Narrative reviewBrain Health forRhodiola
  14. Rhodiola rosea in stress induced fatigue--a double blind cross-over study of a standardized extract SHR-5 with a repeated low-dose regimen on the mental performance of healthy physicians during night duty.
    Darbinyan V; Kteyan A; Panossian A; Gabrielian E; Wikman G; Wagner H · Phytomedicine : international journal of phytotherapy and phytopharmacology · 2001
    Randomized trial56 participantsBrain Health Everyday Health Productivity Boost forRhodiola
  15. Effects of a Rhodiola rosea extract on mental resource allocation and attention: An event-related potential dual task study.
    Koop T; Dienel A; Heldmann M; Münte TF · Phytotherapy research : PTR · 2021
    Single-arm trial50 participantsBrain Health Cognitive Support forRhodiola
  16. Vitamin B12, B6, or Folate and Cognitive Function in Community-Dwelling Older Adults: A Systematic Review and Meta-Analysis.
    Zhang C; Luo J; Yuan C; Ding D · Journal of Alzheimer's disease : JAD · 2021
    Meta-analysis21 studies pooledBrain Health forVitamin B6
  17. Relationship between serum pyridoxal 5'-phosphate concentration and cognitive function in older Japanese.
    Itoh K; Kuwabara A; Otsuka R; Sugimoto T; Sakurai T; Niida S; Ao M; Tanaka K; Takenaka S; Kanouchi H · Journal of clinical biochemistry and nutrition · 2025
    Cross-sectional study266 participantsBrain Health forVitamin B6
  18. A randomized, controlled trial to evaluate the efficacy of pyridoxine and ascorbic acid on cognitive function and quality of life in post-menopausal women.
    Dhivya K; Sarumathy S; Manigandan G · Naunyn-Schmiedeberg's archives of pharmacology · 2025
    Randomized trial180 participantsBrain Health forVitamin B6
  19. Lower Plasma Vitamin B-6 is Associated with 2-Year Cognitive Decline in the Boston Puerto Rican Health Study.
    Palacios N; Scott T; Sahasrabudhe N; Gao X; Tucker KL · The Journal of nutrition · 2020
    Cohort study949 participantsBrain Health Cognitive Support forVitamin B6
  20. Are Dietary Supplements and Nutraceuticals Effective for Musculoskeletal Health and Cognitive Function? A Scoping Review.
    Iolascon G; Gimigliano R; Bianco M; De Sire A; Moretti A; Giusti A; Malavolta N; Migliaccio S; Migliore A; Napoli N; Piscitelli P; Resmini G; Tarantino U; Gimigliano F · The journal of nutrition, health & aging · 2017
    Scoping review12 studies pooledBrain Health forVitamin B6