B-50 Gels

B-50 Gels

Carlson4.7 (379 ratings)
Format:Softgel Quantity: 50 Softgel(s) · 50 servings
Goals
$14.37 $0.28 per serving

Product analysis

65 out of 100

B-50 Gels supplies B vitamins that support normal energy use and may help with tiredness when intake is low. Folate and biotin forms are unspecified, making those ingredients harder to compare with more fully described alternatives.

AI assessment of the formula, label and price. How scoring works

Nutrient Quality57

The B vitamins use a mix of clearly identified forms, with vitamin B5 providing a favorable form choice. Plain riboflavin is less favorable, while folate and biotin forms are omitted.

Ingredient Transparency84

All listed ingredient amounts and several vitamin forms are stated. Folate, biotin and some other preparations are omitted, so the label is clearer about quantities than every ingredient form.

Value For Money48

Vitamin B6 and riboflavin offer good value, while niacin and vitamin B5 are relatively expensive for the amount supplied. Value for several other ingredients remains uncertain.

Customer Satisfaction76

Customer ratings are very positive across hundreds of ratings. The feedback describes satisfaction without establishing effectiveness or safety.

Product Focus67

The main purpose is B-vitamin nutrition for normal energy metabolism. Benefits for tiredness are most relevant when intake is low, rather than as extra energy or greater calorie burning with adequate nutrition.

Format
Softgel
Container
50 Softgel(s)
Per serving
$0.28
Customer rating
4.7 · 379 ratings
Report analysis

Goals

Impact
High effect
A Ingredient FitF PathwaysB EvidenceA+ Formulation Logic
Vitamin B5 · 50 mgRiboflavin · 50 mgThiamin · 50 mgVitamin B12 · 50 mcg

Riboflavin, niacin, vitamin B5, vitamin B6 and folate can help reduce tiredness when low intake or deficiency disrupts normal nutrition or causes anaemia. Their large declared amounts do not establish extra energy when nutritional status is already adequate. Vitamin B12 is present but falls below the amount counted in the saved findings, which is distinct from saying that the declared amount has no nutritional value.

How this product is rated for Energy

Ingredient fit93

Goal-related ingredients share the formula with components aimed at other nutritional or wellness purposes.
Goal fit
Goal-related ingredients share the formula with components aimed at other nutritional or wellness purposes.
Dose adequacy
The saved amount comparison is partial; it does not establish a treatment dose or additional benefit above nutritional adequacy.

Pathways0

The saved findings assign no energy-pathway coverage. Nutritional contributions remain distinct from acute alertness or exercise-fatigue effects.
Depth
No energy pathway received coverage in the saved findings; nutritional recognition is separate.
Breadth
No energy area reaches the saved breadth comparison.

Evidence78

Vitamin B2 (Riboflavin) anchors the saved evidence finding; its relevant benefit depends on correcting low intake or deficiency.
Evidence strength
Vitamin B2 (Riboflavin) anchors the saved evidence finding; its relevant benefit depends on correcting low intake or deficiency.
Studied preparation
The saved findings recognize the counted preparations; this does not establish superiority of their forms.

Formulation logic100

The counted ingredients have no missing required partner or configured sedating conflict, and their amounts meet the saved minimum comparison.
Partner coverage
The counted ingredients have no missing required partner for their assigned contributions.
Conflicts
No configured sedating-ingredient conflict was identified in the supplied findings.
Effective doses
All 6 counted ingredients meet the saved minimum amount comparison; this is not proof of clinical effectiveness.
Study evidence
Thiamin Disputed 12 studies
Impact
High effect
A- Ingredient FitF PathwaysA+ EvidenceA+ Formulation Logic
Biotin · 50 mcgNiacin · 50 mgVitamin B12 · 50 mcgRiboflavin · 50 mgThiamin · 50 mgVitamin B5 · 50 mgVitamin B6 · 50 mg

The B vitamins support normal energy metabolism, without evidence that extra amounts raise calorie expenditure when intake is adequate.

How this product is rated for Metabolism Support

Ingredient fit85

Vitamin B1 (Thiamin) leads the relevant ingredient finding. The saved amount comparison remains distinct from proof of a metabolism boost.
Goal fit
Vitamin B1 (Thiamin) provides a relevant connection within a broader formula, reducing its focus on this goal.
Dose adequacy
The relevant amounts partly match the saved comparison exposures; this limits the amount finding without quantifying a change in calorie expenditure.

Pathways0

Normal metabolic roles do not translate into meaningful coverage of the reviewed energy-expenditure mechanisms.
Depth
No reviewed energy-expenditure mechanism received a meaningful contribution, despite the ingredients’ normal metabolic roles.
Breadth
No reviewed mechanism reaches the saved coverage threshold, so broad energy-expenditure support is not established.

Evidence100

Vitamin B1 (Thiamin) leads the saved evidence comparison. Clinical context limits any claim that these ingredients increase whole-body energy expenditure.
Evidence strength
Vitamin B1 (Thiamin) anchors the saved evidence finding, while the supplied human evidence does not establish a routine metabolism boost in adequately nourished adults.
Studied preparation
The included ingredients match preparations recognized in the saved comparison. Matching a preparation does not establish that it increases calorie expenditure.

Formulation logic100

No missing required partner or matched conflict was identified. The included ingredients meet the saved amount threshold.
Partner coverage
The relevant ingredients act independently or have their required partner; this does not establish an added benefit from their combination.
Conflicts
No conflict was identified in the supplied checks; this is a limited formulation finding rather than a general safety conclusion.
Effective doses
The included ingredients meet the saved amount threshold; this threshold is not a proven minimum dose for increasing metabolism.
Study evidence
Biotin Supportive 5 studies
Niacin Supportive 17 studies
Thiamin Supportive 11 studies
Vitamin B6 Supportive 16 studies

Ingredients

IngredientAmount per servingScore
Calories
10 Calorie(s)
Total Fat
1 Gram(s)
Protein
1 Gram(s)
Thiamine (Thiamine Mononitrate)
50 mg 76
Riboflavin
50 mg 68
Niacin (Niacinamide)
50 mg 65
Vitamin B6 (Pyridoxine Hydrochloride)
50 mg 75
Folate
680 mcg DFE
Vitamin B12 (Cyanocobalamin)
50 mcg
Biotin
50 mcg
Pantothenic Acid (D-Calcium Pantothenate)
50 mg 70
Phosphatidyl Choline (Soybeans)
50 mg
Gluten Free Adults 18–50 Women
Report overview
A+ Ingredient Form & Label QualityF Dose, Safety & Label TransparencyA+ Value
Each serving provides 50 mg of vitamin B6 as pyridoxine hydrochloride, which exceeds the European adult daily upper limit. The whole-product serving costs about $0.29 and has a low price per mg of B6, but the amount remains a concern.
How this ingredient is rated

Ingredient Form & Label Quality100

The B6 source is identified as pyridoxine hydrochloride. The evaluation records no artificial dyes, titanium dioxide or talc among the checked markers.
Vitamin B6 Form Identification
The B6 source is identified as pyridoxine hydrochloride.
Clean Label and Excipient Purity
The evaluation records no artificial dyes, titanium dioxide or talc among the checked markers.

Dose, Safety & Label Transparency37

The identified source is pyridoxine hydrochloride. The 50 mg of B6 per serving exceeds the European adult daily upper limit.
Vitamin B6 Dose & Safety Policy
The 50 mg of B6 per serving exceeds the European adult daily upper limit.
Label Transparency
The chemical source of B6 is identified as pyridoxine hydrochloride.

Value99

The whole-product serving costs about $0.29; based on its B6 content, that is a low cost per mg in the comparison.
Vitamin B6 Price Efficiency
The whole-product price works out to about $0.0057 per mg of B6; the serving price also covers the other ingredients.
B- Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyD- Value
Each serving provides 50 mg of thiamin from thiamine mononitrate, a standard water-soluble form. The evaluation considers that a high amount for its dose comparison.
How this ingredient is rated

Active Ingredient Quality & Bioavailability70

Thiamine Mononitrate is a standard water-soluble source of thiamin. The evaluation does not flag the specified artificial colors or sweeteners in the saved information.
Thiamin Chemical Form
Thiamine Mononitrate is a standard water-soluble form of thiamin.
Excipient Purity
The evaluation does not flag the specified artificial colors or sweeteners in the saved information.

Dose, Safety & Label Transparency100

The serving supplies 50 mg of thiamin, which the evaluation considers a high amount. The amount is separately specified.
Thiamin Dosage Potency
The declared 50 mg of thiamin is considered a high amount in the evaluation.
Label Transparency & Proprietary Blends
The amount is stated as 50 mg of thiamin per serving.

Value40

The normalized cost is about $0.57 per 100 mg of thiamin, in the higher band used for this evaluation. It reflects the cost of the whole product, including its other contents.
Price per Declared Dose
The cost is about $0.57 per 100 mg of thiamin, based on whole-product pricing; the evaluation places it in the higher band.
Riboflavin · 50 mg OverallScore68
F Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyB+ Value
The serving lists 50 mg of standard riboflavin, a higher amount in this comparison. The body converts this form to an active form, and the whole-product price is about $0.29 per serving.
How this ingredient is rated

Active Ingredient Quality & Bioavailability30

Standard riboflavin requires conversion in the body to its active form.
Riboflavin Form Quality
Standard riboflavin requires conversion in the body to its active form.

Dose, Safety & Label Transparency100

The serving lists 50 mg of standard riboflavin, a higher amount in this comparison.
Dosage for Energy & Metabolism
The 50 mg of riboflavin per serving is a higher amount in this comparison.
R5P Elemental Yield Transparency
The phosphate-compound yield issue does not apply to standard riboflavin.
Additive Purity
The evaluated ingredient information did not identify artificial dyes or synthetic sweeteners.

Value80

The whole-product price is about $0.29 per serving, relatively low in this comparison.
Price per Serving Value
The whole-product price is about $0.29 per serving, relatively low in this comparison.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Physicochemical properties of and volatile compounds in riboflavin fortified cloudy apple juice; study of its effect on job fatigue among Egyptian construction workers.
    Fouad S; Ibrahim GE; Hussein AMS; Ibrahim FA; El Gendy A · Heliyon · 2021
    Non-randomized trialEnergy forRiboflavin
  2. Vitamin B status in patients with chronic fatigue syndrome.
    Heap LC; Peters TJ; Wessely S · Journal of the Royal Society of Medicine · 1999
    Case-control study30 participantsEnergy forRiboflavin
  3. B-vitamins, related vitamers, and metabolites in patients with quiescent inflammatory bowel disease and chronic fatigue treated with high dose oral thiamine.
    Bager P; Hvas CL; Hansen MM; Ueland P; Dahlerup JF · Molecular medicine (Cambridge, Mass.) · 2023
    Observational studyEnergy forRiboflavin
  4. Metabolic features of chronic fatigue syndrome.
    Naviaux RK; Naviaux JC; Li K; Bright AT; Alaynick WA; Wang L; Baxter A; Nathan N; Anderson W; Gordon E · Proceedings of the National Academy of Sciences of the United States of America · 2024
    Case-control study84 participantsEnergy forRiboflavin
  5. Effectiveness of Riboflavin in Inherited Metabolic Diseases: A Systematic Review
    Bregje Jaeger, Nina N Stolwijk, Femke Aaldering, Charlotte A Ruys, Marije Smits, Nicole I Wolf, Carla E M Hollak, Annet M Bosch · Journal of Inherited Metabolic Disease · 2026
    Systematic review381 studies pooledEnergy Metabolism Support forRiboflavin
  6. Influence of thiamin supplementation on the health and general well-being of an elderly Irish population with marginal thiamin deficiency.
    Smidt LJ; Cremin FM; Grivetti LE; Clifford AJ · Journal of gerontology · 1991
    Randomized trial80 participantsEnergy forThiamin
  7. Randomised clinical trial: high-dose oral thiamine versus placebo for chronic fatigue in patients with quiescent inflammatory bowel disease.
    Bager P; Hvas CL; Rud CL; Dahlerup JF · Alimentary pharmacology & therapeutics · 2021
    Randomized trial40 participantsEnergy forThiamin
  8. Dietary reference values for thiamin.
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA); Turck D; Bresson JL; Burlingame B; Dean T; Fairweather-Tait S; Heinonen M; Hirsch-Ernst KI; Mangelsdorf I; McArdle HJ; Naska A; Nowicka G; Pentieva K; Sanz Y; Siani A; Sjödin A; Stern M; Tomé D; Van Loveren H; Vinceti M; Willatts P; Lamberg-Allardt C; Przyrembel H; Tetens I; Gudelj Rakic J; Ioannidou S; de Sesmaisons-Lecarré A; Forss AC; Neuhäuser-Berthold M · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusEnergy forThiamin
  9. Effects of thiamine supplementation on exercise-induced fatigue.
    Suzuki M; Itokawa Y · Metabolic brain disease · 1996
    Randomized trial16 participantsEnergy forThiamin
  10. Long-term maintenance treatment with 300 mg thiamine for fatigue in patients with inflammatory bowel disease: results from an open-label extension of the TARIF study.
    Bager P; Hvas CL; Rud CL; Dahlerup JF · Scandinavian journal of gastroenterology · 2022
    Randomized trialEnergy forThiamin
  11. A new perspective on vitamin B12 deficiency in rheumatology: a case-based review.
    Dułak NA; Rytlewska M; Jaskólska M; Chmielewski M · Rheumatology international · 2024
    Case series3 participantsEnergy forVitamin B12
  12. Effects of Vitamin B12 Supplementation on Cognitive Function, Depressive Symptoms, and Fatigue: A Systematic Review, Meta-Analysis, and Meta-Regression.
    Markun S; Gravestock I; Jäger L; Rosemann T; Pichierri G; Burgstaller JM · Nutrients · 2021
    Meta-analysis6,276 participants16 studies pooledEnergy forVitamin B12
  13. Patients' experiences with methylcobalamin injections in amyotrophic lateral sclerosis.
    Zubair AS; Saab L; Scharer K; Khokhar B · Brain circulation · 2024
    Qualitative study5 participantsEnergy forVitamin B12
  14. Cobalamin deficiency: clinical picture and radiological findings.
    Briani C; Dalla Torre C; Citton V; Manara R; Pompanin S; Binotto G; Adami F · Nutrients · 2014
    Narrative reviewEnergy forVitamin B12
  15. Vitamin B12 Deficiency: Common Questions and Answers.
    Patel H; McGuirk R · American family physician · 2025
    Narrative reviewEnergy forVitamin B12
  16. Biotin and contribution to normal energy-yielding metabolism: evaluation of a health claim pursuant to Article 14 of Regulation (EC) No 1924/2006.
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusMetabolism Support forBiotin
  17. Pregnancy and lactation alter biomarkers of biotin metabolism in women consuming a controlled diet.
    Perry CA; West AA; Gayle A; Lucas LK; Yan J; Jiang X; Malysheva O; Caudill MA · The Journal of nutrition · 2015
    Clinical trial75 participantsMetabolism Support forBiotin
  18. Survey of the effect of biotin on glycemic control and plasma lipid concentrations in type 1 diabetic patients in kermanshah in iran (2008-2009)
    Hemmati M, Babaei H, Abdolsalehei M · Oman Medical Journal · 2013
    Randomized trial70 participantsMetabolism Support forBiotin
  19. Chromium picolinate and biotin combination improves glucose metabolism in treated, uncontrolled overweight to obese patients with type 2 diabetes
    César A Albarracin, Bobby C Fuqua, James L Evans, Ira D Goldfine · Diabetes/Metabolism Research and Reviews · 2008
    Randomized trial348 participantsMetabolism Support forBiotin
  20. Biotin supplementation reduces plasma triacylglycerol and VLDL in type 2 diabetic patients and in nondiabetic subjects with hypertriglyceridemia
    Cristina Revilla-Monsalve, Iván Zendejas-Ruiz, Sergio Islas-Andrade, Armida Báez-Saldaña, Miguel Angel Palomino-Garibay, Pedro Martín Hernández-Quiróz, Cristina Fernandez-Mejia · Biomedicine & Pharmacotherapy · 2006
    Randomized trial33 participantsMetabolism Support forBiotin