Thyroid Synergy

Thyroid Synergy

Designs for Health4.9 (176 ratings)
Format:Capsule Quantity: 120 Capsule(s) · 60 servings
Goals
$49.99 $0.83 per serving

About this product

The formula covers several nutrients involved in normal thyroid and energy metabolism, including 100 mcg iodine, riboflavin, zinc and selenium. Its clearest fit is filling specific nutrient gaps rather than producing broad thyroid or hormone effects.

Label detail is a strength: amounts are stated throughout, and nearly every ingredient has a named form. Zinc glycinate, manganese glycinate and chromium nicotinate glycinate are useful form disclosures, while the N-acetyl L-tyrosine form is not identified and quality findings for several other ingredients remain uncertain.

The 25 mg zinc serving stands out, but only 0.5 mg copper accompanies it, creating a zinc-heavy 50:1 balance in the supplied assessment. The formula also carries a relatively high serving cost, and its wide mix of vitamins, minerals and botanicals makes it less focused for any single goal.

Who is it for
  • Adults whose diet may be low in iodine, zinc, selenium or riboflavin
  • People who prefer clearly stated ingredient amounts and mostly named forms
  • Users seeking broad nutritional support rather than a single-ingredient supplement
Best for
  • Nutritional support when iodine or zinc intake is low
  • Normal energy metabolism and antioxidant nutrient coverage
  • People comfortable with a broad capsule formula

Pros

  • Discloses all active amounts and nearly all forms
  • Provides 100 mcg iodine and 25 mg zinc per serving
  • Uses clearly identified chelated forms for zinc, copper, manganese and chromium
  • Includes riboflavin, selenium and other nutrients with complementary nutritional roles

Cons

  • Relatively high cost for the amounts of several nutrients
  • The 50:1 zinc-to-copper balance is less favorable in the supplied assessment
  • N-acetyl L-tyrosine form is not disclosed
  • Broad ingredient mix reduces focus for any one stated goal

Warnings

  • The 25 mg zinc serving is paired with only 0.5 mg copper; long-term use alongside other zinc products could further skew zinc and copper intake.
  • The formula contains iodine, so people already managing thyroid function or using thyroid medication should confirm that added iodine fits their plan.

Product analysis

64 out of 100

Thyroid Synergy may help fill nutrient gaps relevant to normal thyroid, immune and skin functions. Its zinc form is a quality strength, though the full product is relatively expensive for several nutrients.

AI assessment of the formula, label and price. How scoring works

Nutrient Quality58

The zinc form is a clear quality strength, with positive findings also for chromium and manganese. Quality conclusions for most other ingredients remain uncertain.

Ingredient Transparency97

Amounts and almost all forms are disclosed, which makes ingredient comparisons straightforward. Only the N-acetyl tyrosine form lacks those details.

Value For Money33

The full product cost is relatively high when considered for zinc, vitamin A, manganese or chromium. Value for the remaining nutrients is uncertain.

Customer Satisfaction76

Customers give strongly positive feedback. The moderate review base gives useful perspective on satisfaction without proving thyroid benefits.

Product Focus63

The clearest role is nutritional support when intake is low, including iodine for normal thyroid function. The wider eye, hair and hormone claims are conditional, and the vitamin A amount remains unclear for judging its contribution.

Format
Capsule
Container
120 Capsule(s)
Per serving
$0.83
Customer rating
4.9 · 176 ratings
Report analysis

Goals

Immunity
Impact
High effect
D+ Ingredient FitC- PathwaysA+ EvidenceA Formulation Logic
Zinc · 25 mgVitamin A · 2000 IUSelenium · 50 mcg
Study evidence
Selenium Mixed 37 studies
Vitamin A Supportive 107 studies
Zinc Supportive 73 studies
Everyday Health
Impact
High effect
B- Ingredient FitB+ PathwaysB+ EvidenceA+ Formulation Logic
Selenium · 50 mcgZinc · 25 mg
Study evidence
Selenium Supportive 70 studies
Zinc Supportive 60 studies
Impact
Moderate effect
C- Ingredient FitF PathwaysA EvidenceA+ Formulation Logic
Zinc · 25 mg
Study evidence
Selenium No effect 16 studies
Zinc Disputed 7 studies
Hair Health
Impact
Moderate effect
C Ingredient FitF PathwaysA+ EvidenceA+ Formulation Logic
Zinc · 25 mg
Study evidence
Copper Adverse 4 studies
Iodine No effect 1 study
Selenium Disputed 7 studies
Vitamin A Disputed 13 studies
Zinc Supportive 22 studies
Impact
High effect
C- Ingredient FitB+ PathwaysA- EvidenceA+ Formulation Logic
Zinc · 25 mgCopper · 500 mcgVitamin A · 2000 IU
Study evidence
Copper Supportive 7 studies
Riboflavin Supportive 69 studies
Selenium Supportive 15 studies
Vitamin A Supportive 65 studies
Zinc Supportive 39 studies
Skin Health
Impact
Moderate effect
C- Ingredient FitF PathwaysA- EvidenceA+ Formulation Logic
Zinc · 25 mgCopper · 500 mcgSelenium · 50 mcg
Study evidence
Copper Supportive 16 studies
Selenium Supportive 22 studies
Vitamin A Supportive 106 studies
Zinc Supportive 66 studies

Ingredients

IngredientAmount per servingScore
Vitamin A (Vitamin A Palmitate)
2000 IU 36
Riboflavin (Riboflavin 5-Phosphate)
5 mg
Iodine (Potassium Iodide)
100 mcg
Zinc (TRAACS Zinc Glycinate Chelate)
25 mg 78
Selenium (Selenomethionine)
50 mcg
Copper (TRAACS Copper Glycinate Chelate)
500 mcg
Manganese (TRAACS Manganese Glycinate Chelate)
5 mg 72
Chromium (TRAACS Chromium Nicotinate Glycinate Chelate)
50 mcg 48
N-Acetyl L-Tyrosine
200 mg
American Ginseng (Ginsenosides)
200 mg
ForsLean(R) Extract (Forskolin)
50 mg
Gluten Free Adults 18–50
Report overview
B- Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyF Value
It provides 5 mg of manganese per serving at a high cost per serving, an amount aligned with the stated bone and joint support purpose. The source is manganese glycinate.
How this ingredient is rated

Active Ingredient Quality & Bioavailability70

The source is manganese glycinate; its form has a provisional assessment.
Manganese Chemical Form
The source is manganese glycinate; its form has a provisional assessment.

Dose, Safety & Label Transparency100

The serving provides 5 mg of manganese, an amount aligned with the stated bone and joint support purpose. The amount is clearly stated.
Manganese Dosage Efficacy & Safety
5 mg per serving is an amount aligned with the stated bone and joint support purpose.
Elemental Weight Disclosure
The label states both the manganese amount and its source.

Value20

The cost per serving is high.
Price per Serving vs. Median
The cost per serving is high.
A+ Active Ingredient Quality & BioavailabilityB Dose, Safety & Label TransparencyF Value
Each serving provides 25 mg of zinc at a high cost per serving. It uses Zinc Bisglycinate, and the amount is substantial. It also provides 0.5 mg of copper.
How this ingredient is rated

Active Ingredient Quality & Bioavailability100

The zinc is supplied as Zinc Bisglycinate.
Zinc Form Bioavailability
The zinc comes from Zinc Bisglycinate.

Dose, Safety & Label Transparency79

The label states 25 mg of zinc per serving, a substantial amount. It also contains 0.5 mg of copper, giving a zinc-to-copper ratio of 50:1.
Elemental Dose Transparency
The label states both the 25 mg zinc amount and its source.
Zinc Dosage Safety & Effectiveness
The 25 mg per serving is a substantial amount.
Zinc-to-Copper Mineral Balance
It also contains 0.5 mg of copper, giving a zinc-to-copper ratio of 50:1.

Value30

The cost per serving is high.
Price Per Serving Efficiency
The cost per serving is high.
F Active Ingredient Quality & BioavailabilityD Dose, Safety & Label TransparencyF Value
A serving provides 2,000 IU of vitamin A at a high cost for the vitamin A amount. The source is retinyl palmitate.
How this ingredient is rated

Active Ingredient Quality & Bioavailability30

The source is retinyl palmitate.
Vitamin A Chemical Form & Source
The source is retinyl palmitate.

Dose, Safety & Label Transparency49

A serving provides 2,000 IU of vitamin A. The source is named as retinyl palmitate.
Dosage Efficacy & Safety Thresholds
A serving provides 2,000 IU of vitamin A.
Label Transparency of Specific Forms
The source is retinyl palmitate.

Value20

The cost for the vitamin A amount is high.
Price per 5,000 IU Dose
The cost for the vitamin A amount is high.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Associations of selenium status with all-cause and cause-specific mortality: a systematic review and meta-analysis of cohort studies.
    Cui Z; Xie R; Lu X; Schomburg L; Brenner H; Schöttker B · Redox biology · 2025
    Meta-analysis95 participants20 studies pooledEveryday Health forSelenium
  2. Dietary Antioxidants, Circulating Antioxidant Concentrations, Total Antioxidant Capacity, and Risk of All-Cause Mortality: A Systematic Review and Dose-Response Meta-Analysis of Prospective Observational Studies.
    Jayedi A; Rashidy-Pour A; Parohan M; Zargar MS; Shab-Bidar S · Advances in nutrition (Bethesda, Md.) · 2019
    Meta-analysis507,251 participants41 studies pooledEveryday Health forSelenium
  3. The efficacy and safety of selenium supplementation versus placebo in the treatment of Graves' orbitopathy: A systematic review and meta-analysis of randomised controlled trials.
    Sharabati I; Qafesha RM; Hindawi MD; Amro S; Ayesh BM · Clinical endocrinology · 2024
    Meta-analysis4 studies pooledEveryday Health Eye Health forSelenium
  4. Associations of plasma metal concentrations with the risks of all-cause and cardiovascular disease mortality in Chinese adults.
    Shi L; Yuan Y; Xiao Y; Long P; Li W; Yu Y; Liu Y; Liu K; Wang H; Zhou L; Yang H; Li X; He M; Wu T · Environment international · 2021
    Cohort study6,155 participantsEveryday Health forSelenium
  5. Updates on clinical studies of selenium supplementation in radiotherapy.
    Puspitasari IM; Abdulah R; Yamazaki C; Kameo S; Nakano T; Koyama H · Radiation oncology (London, England) · 2015
    Systematic review16 studies pooledEveryday Health forSelenium
  6. Effectiveness of sodium bicarbonate and zinc chloride mouthwashes in the treatment of oral mucositis and quality of life in patients with cancer under chemotherapy.
    Mohammadi F; Oshvandi K; Kamallan SR; Khazaei S; Ranjbar H; Ahmadi-Motamayel F; Gillespie M; Jenabi E; Vafaei SY · Nursing open · 2022
    Randomized trial144 participantsEveryday Health forZinc
  7. Zinc supplementation in young children with acute diarrhea in India.
    Sazawal S; Black RE; Bhan MK; Bhandari N; Sinha A; Jalla S · The New England journal of medicine · 1995
    Randomized trial937 participantsEveryday Health forZinc
  8. Associations of mortality with ocular disorders and an intervention of high-dose antioxidants and zinc in the Age-Related Eye Disease Study: AREDS Report No. 13.
    Clemons TE; Kurinij N; Sperduto RD; AREDS Research Group · Archives of ophthalmology (Chicago, Ill. : 1960) · 2004
    Randomized trial4,753 participantsEveryday Health forZinc
  9. Effects of zinc and probiotic co-supplementation on inflammation, gastrointestinal symptoms, quality of life, and mood in irritable bowel syndrome patients.
    Rezazadegan M; Soheilipour M; Amani R · Scientific reports · 2026
    Randomized trial84 participantsEveryday Health forZinc
  10. Effect of zinc sulfate supplementation on premenstrual syndrome and health-related quality of life: Clinical randomized controlled trial.
    Siahbazi S; Behboudi-Gandevani S; Moghaddam-Banaem L; Montazeri A · The journal of obstetrics and gynaecology research · 2018
    Randomized trial142 participantsEveryday Health forZinc
  11. What did we learn in 35 years of research on nutrition and supplements for age-related macular degeneration: a systematic review.
    Pameijer EM; Heus P; Damen JAA; Spijker R; Hooft L; Ringens PJ; Imhof SM; van Leeuwen R · Acta ophthalmologica · 2023
    Systematic review27 studies pooledEye Health forCopper
  12. Dietary Nutrient Intake and Progression to Late Age-Related Macular Degeneration in the Age-Related Eye Disease Studies 1 and 2.
    Agrón E; Mares J; Clemons TE; Swaroop A; Chew EY; Keenan TDL; AREDS and AREDS2 Research Groups · Ophthalmology · 2021
    Cohort study8,242 participantsEye Health forCopper
  13. Association between late age-related macular degeneration and dietary intake of copper, iron, zinc and selenium: a 2005-2008 NHANES cross-sectional observational study.
    Lu Y; Li C; Liu Y; Wu T; Lu P · BMC ophthalmology · 2025
    Observational study4,996 participantsEye Health forCopper
  14. Associations between dietary nutrient intake and the risk of multiple age-related ocular diseases: evidence from longitudinal analysis.
    Yang Y; Zou H · The journal of nutrition, health & aging · 2026
    Cohort study103,192 participantsEye Health forCopper
  15. Dietary habits and dietary nutrient intake in patients with age-related macular degeneration: A case-control study.
    Šalková Kráľová J; Kolář P; Kapounová Z; Veselý P; Derflerová Brázdová Z · Central European journal of public health · 2023
    Case-control study151 participantsEye Health forCopper
  16. U.S. Multicenter Clinical Trial of Corneal Collagen Crosslinking for Treatment of Corneal Ectasia after Refractive Surgery.
    Hersh PS; Stulting RD; Muller D; Durrie DS; Rajpal RK; U.S. Crosslinking Study Group · Ophthalmology · 2017
    Randomized trial179 participantsEye Health forRiboflavin
  17. United States Multicenter Clinical Trial of Corneal Collagen Crosslinking for Keratoconus Treatment.
    Hersh PS; Stulting RD; Muller D; Durrie DS; Rajpal RK; United States Crosslinking Study Group · Ophthalmology · 2017
    Randomized trial205 participantsEye Health forRiboflavin
  18. EpiSmart Crosslinking for Keratoconus: A Phase 2 Study.
    Epstein RJ; Belin MW; Gravemann D; Littner R; Rubinfeld RS · Cornea · 2023
    Randomized trial2,228 participantsEye Health forRiboflavin
  19. Prospective Randomized Trial of Corneal Cross-linking Riboflavin Dosing Frequencies for Treatment of Keratoconus and Corneal Ectasia.
    Price MO; Fairchild K; Feng MT; Price FW · Ophthalmology · 2019
    Randomized trial510 participantsEye Health forRiboflavin
  20. Corneal collagen cross-linking for keratoconus: results of 3-year follow-up in Pakistani population.
    Khan WA; Zaheer N; Khan S · Canadian journal of ophthalmology. Journal canadien d'ophtalmologie · 2015
    Non-randomized trial66 participantsEye Health forRiboflavin