Super B-Complex with Folic Acid plus Vitamin C

Super B-Complex with Folic Acid plus Vitamin C

Nature's Bounty4.7 (71,274 ratings)
Format:Tablet Quantity: 150 Tablet(s) · 150 servings
Goals
$13.43 $0.08 per serving

Product analysis

71 out of 100

Super B-Complex with Folic Acid plus Vitamin C combines nutrients involved in normal energy use with vitamin C. Low cost for several B vitamins supports value, though comparative quality remains uncertain for part of the formula.

AI assessment of the formula, label and price. How scoring works

Nutrient Quality53

D-biotin and clearly identified niacinamide are useful strengths, while the thiamin and riboflavin preparations are more basic. Quality remains uncertain for several other vitamins, so the whole mixture cannot be judged equally confidently.

Ingredient Transparency96

Ingredient amounts and nearly all vitamin forms are stated, helping compare the formula. The folate form remains unspecified, leaving that preparation less clear.

Value For Money56

The serving cost is favorable for riboflavin and niacin, while thiamin offers more limited value. The other nutrients make a biotin-only cost comparison less informative, and the remaining vitamin comparisons are uncertain.

Customer Satisfaction92

Customer ratings are very positive across a very large body of responses. The breadth makes the satisfaction picture more informative without establishing health benefits.

Product Focus69

The combination keeps a coherent focus on B-vitamin nutrition with added vitamin C. Its several related purposes do not establish an extra energy boost for everyone.

Format
Tablet
Container
150 Tablet(s)
Per serving
$0.08
Customer rating
4.7 · 71,274 ratings
Report analysis

Goals

Impact
Highest effect
A Ingredient FitB+ PathwaysB+ EvidenceA+ Formulation Logic
Folate · 666 mcg DFEVitamin B12 · 100 mcgVitamin C · 60 mg
Study evidence
Folate Supportive 80 studies
Vitamin C Supportive 56 studies
Impact
High effect
A- Ingredient FitF PathwaysB EvidenceA+ Formulation Logic
Vitamin B5 · 5.5 mgRiboflavin · 20 mgThiamin · 25 mgVitamin B12 · 100 mcg
Study evidence
Thiamin Disputed 12 studies
Impact
High effect
B Ingredient FitF PathwaysA+ EvidenceA+ Formulation Logic
Biotin · 1000 mcgNiacin · 25 mgVitamin B12 · 100 mcgRiboflavin · 20 mgThiamin · 25 mgVitamin B5 · 5.5 mgVitamin B6 · 5 mg
Study evidence
Biotin Supportive 5 studies
Niacin Supportive 17 studies
Thiamin Supportive 11 studies
Vitamin B6 Supportive 16 studies
Impact
High effect
B+ Ingredient FitF PathwaysB+ EvidenceA+ Formulation Logic
Biotin · 1000 mcgVitamin C · 60 mg
Study evidence
Biotin Supportive 4 studies
Folate Mixed 15 studies
Niacin Disputed 2 studies

Ingredients

IngredientAmount per servingScore
Vitamin C (Ascorbic Acid)
60 mg
Thiamine (Thiamine Mononitrate)
25 mg 65
Riboflavin
20 mg 58
Niacin (Niacinamide)
25 mg 81
Vitamin B6 (Pyridoxine Hydrochloride)
5 mg
Folate
666 mcg DFE
Vitamin B12 (Cyanocobalamin)
100 mcg 21
Biotin (D-Biotin)
1000 mcg 76
Pantothenic Acid (D-Calcium Pantothenate)
5.5 mg
Gluten Free Adults 18–50 Dairy Free Sugar Free Vegetarian
Report overview
A- Active Ingredient Quality & BioavailabilityC+ Dose, Safety & Label TransparencyA+ Value
A serving provides 25 mg of niacin as niacinamide at a low cost per serving. Niacinamide is a non-flushing form, and the amount and source are stated.
How this ingredient is rated

Active Ingredient Quality & Bioavailability86

Niacinamide provides a standard form of niacin.
Niacin Form & Goal Alignment
Niacinamide is a form used for general niacin support.
Precursor Source Quality
The niacin source is niacinamide.

Dose, Safety & Label Transparency67

The serving contains 25 mg of niacin. The niacinamide form is non-flushing.
Clarity of Chemical Form
Both the niacin amount and niacinamide form are stated.
Form-Specific Dosage Efficacy
The serving contains 25 mg of niacin.
Flush Risk & Safety Labeling
Niacinamide is a non-flushing form.

Value100

The cost per serving is low for the niacin contribution.
Price Per Effective Serving
The cost per serving is low for the niacin contribution.
A+ Active Ingredient Quality & BioavailabilityC Dose, Safety & Label TransparencyC Value
A serving provides 1000 mcg of biotin. The biotin-only cost appears high, but it assigns the full serving price to biotin and includes other nutrients. The listed form is D-biotin. No artificial colors or sweeteners are recorded.
How this ingredient is rated

Active Ingredient Quality & Bioavailability100

The listed form is D-biotin. No artificial colors or sweeteners are recorded.
Biologically Active d-Biotin Isomer
The listed form is D-biotin.
Excipient Purity
No artificial colors or sweeteners are recorded.

Dose, Safety & Label Transparency60

A serving provides 1000 mcg of biotin. The amount is stated clearly.
Biotin Potency for Health Goals
A serving provides 1000 mcg of biotin.
Label Transparency & Exact Disclosure
The label states the biotin amount per serving.

Value60

The biotin-only cost appears high, but it assigns the full serving price to biotin and includes other nutrients. It also includes vitamin B5, calcium.
Price per 5,000 mcg Biotin
The biotin-only cost appears high, but it assigns the full serving price to biotin and includes other nutrients. It also includes vitamin B5, calcium.
B- Active Ingredient Quality & BioavailabilityB- Dose, Safety & Label TransparencyD- Value
Each serving provides 25 mg of thiamin, with a high cost per 100 mg. It uses Thiamine Mononitrate. The amount is a moderate amount.
How this ingredient is rated

Active Ingredient Quality & Bioavailability70

Thiamine Mononitrate is named. The ingredient information does not establish an additive-free formula.
Thiamin Chemical Form
Thiamine Mononitrate is the named thiamin form.
Excipient Purity
The available ingredient information does not indicate the specified unwanted additives, though it does not establish an additive-free formula.

Dose, Safety & Label Transparency72

The label states 25 mg per serving, a moderate amount of thiamin.
Thiamin Dosage Potency
25 mg per serving is a moderate amount of thiamin.
Label Transparency & Proprietary Blends
The thiamin amount is stated as 25 mg per serving.

Value40

The cost per 100 mg of declared thiamin is high.
Price per Declared Dose
The cost per 100 mg of declared thiamin is high.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Physicochemical properties of and volatile compounds in riboflavin fortified cloudy apple juice; study of its effect on job fatigue among Egyptian construction workers.
    Fouad S; Ibrahim GE; Hussein AMS; Ibrahim FA; El Gendy A · Heliyon · 2021
    Non-randomized trialEnergy forRiboflavin
  2. Vitamin B status in patients with chronic fatigue syndrome.
    Heap LC; Peters TJ; Wessely S · Journal of the Royal Society of Medicine · 1999
    Case-control study30 participantsEnergy forRiboflavin
  3. B-vitamins, related vitamers, and metabolites in patients with quiescent inflammatory bowel disease and chronic fatigue treated with high dose oral thiamine.
    Bager P; Hvas CL; Hansen MM; Ueland P; Dahlerup JF · Molecular medicine (Cambridge, Mass.) · 2023
    Observational studyEnergy forRiboflavin
  4. Metabolic features of chronic fatigue syndrome.
    Naviaux RK; Naviaux JC; Li K; Bright AT; Alaynick WA; Wang L; Baxter A; Nathan N; Anderson W; Gordon E · Proceedings of the National Academy of Sciences of the United States of America · 2024
    Case-control study84 participantsEnergy forRiboflavin
  5. Effectiveness of Riboflavin in Inherited Metabolic Diseases: A Systematic Review
    Bregje Jaeger, Nina N Stolwijk, Femke Aaldering, Charlotte A Ruys, Marije Smits, Nicole I Wolf, Carla E M Hollak, Annet M Bosch · Journal of Inherited Metabolic Disease · 2026
    Systematic review381 studies pooledEnergy Metabolism Support forRiboflavin
  6. Influence of thiamin supplementation on the health and general well-being of an elderly Irish population with marginal thiamin deficiency.
    Smidt LJ; Cremin FM; Grivetti LE; Clifford AJ · Journal of gerontology · 1991
    Randomized trial80 participantsEnergy forThiamin
  7. Randomised clinical trial: high-dose oral thiamine versus placebo for chronic fatigue in patients with quiescent inflammatory bowel disease.
    Bager P; Hvas CL; Rud CL; Dahlerup JF · Alimentary pharmacology & therapeutics · 2021
    Randomized trial40 participantsEnergy forThiamin
  8. Dietary reference values for thiamin.
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA); Turck D; Bresson JL; Burlingame B; Dean T; Fairweather-Tait S; Heinonen M; Hirsch-Ernst KI; Mangelsdorf I; McArdle HJ; Naska A; Nowicka G; Pentieva K; Sanz Y; Siani A; Sjödin A; Stern M; Tomé D; Van Loveren H; Vinceti M; Willatts P; Lamberg-Allardt C; Przyrembel H; Tetens I; Gudelj Rakic J; Ioannidou S; de Sesmaisons-Lecarré A; Forss AC; Neuhäuser-Berthold M · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusEnergy forThiamin
  9. Effects of thiamine supplementation on exercise-induced fatigue.
    Suzuki M; Itokawa Y · Metabolic brain disease · 1996
    Randomized trial16 participantsEnergy forThiamin
  10. Long-term maintenance treatment with 300 mg thiamine for fatigue in patients with inflammatory bowel disease: results from an open-label extension of the TARIF study.
    Bager P; Hvas CL; Rud CL; Dahlerup JF · Scandinavian journal of gastroenterology · 2022
    Randomized trialEnergy forThiamin
  11. A new perspective on vitamin B12 deficiency in rheumatology: a case-based review.
    Dułak NA; Rytlewska M; Jaskólska M; Chmielewski M · Rheumatology international · 2024
    Case series3 participantsEnergy forVitamin B12
  12. Effects of Vitamin B12 Supplementation on Cognitive Function, Depressive Symptoms, and Fatigue: A Systematic Review, Meta-Analysis, and Meta-Regression.
    Markun S; Gravestock I; Jäger L; Rosemann T; Pichierri G; Burgstaller JM · Nutrients · 2021
    Meta-analysis6,276 participants16 studies pooledEnergy forVitamin B12
  13. Patients' experiences with methylcobalamin injections in amyotrophic lateral sclerosis.
    Zubair AS; Saab L; Scharer K; Khokhar B · Brain circulation · 2024
    Qualitative study5 participantsEnergy forVitamin B12
  14. Cobalamin deficiency: clinical picture and radiological findings.
    Briani C; Dalla Torre C; Citton V; Manara R; Pompanin S; Binotto G; Adami F · Nutrients · 2014
    Narrative reviewEnergy forVitamin B12
  15. Vitamin B12 Deficiency: Common Questions and Answers.
    Patel H; McGuirk R · American family physician · 2025
    Narrative reviewEnergy forVitamin B12
  16. Intakes of Folate, Vitamin B6, and Vitamin B12 in Relation to All-Cause and Cause-Specific Mortality: A National Population-Based Cohort.
    Bo Y; Xu H; Zhang H; Zhang J; Wan Z; Zhao X; Yu Z · Nutrients · 2022
    Cohort study55,569 participantsEveryday Health forFolate
  17. The responsiveness of plasma homocysteine to small increases in dietary folic acid: a primary care study.
    Schorah CJ; Devitt H; Lucock M; Dowell AC · European journal of clinical nutrition · 1998
    Randomized trial119 participantsEveryday Health forFolate
  18. Associations of Serum Folate and Homocysteine Concentrations with All-Cause, Cardiovascular Disease, and Cancer Mortality in Men and Women in Korea: the Cardiovascular Disease Association Study.
    Song S; Song BM; Park HY · The Journal of nutrition · 2023
    Cohort study21,260 participantsEveryday Health forFolate
  19. The concept of folic acid supplementation and its role in prevention of neural tube defect among pregnant women: PRISMA.
    Seyoum Tola F · Medicine · 2024
    Systematic reviewEveryday Health forFolate
  20. Systematic review of adverse health outcomes associated with high serum or red blood cell folate concentrations.
    Colapinto CK; O'Connor DL; Sampson M; Williams B; Tremblay MS · Journal of public health (Oxford, England) · 2017
    Systematic review71,847 participants46 studies pooledEveryday Health forFolate