$41.99 $0.69 per serving
Product analysis
Coenzyme B-Complex Advanced provides nutrients that help the body use food for energy and support normal blood formation when intake is low. The coenzyme and methylated forms do not establish extra health benefits when nutrition is already adequate.
AI assessment of the formula, label and price. How scoring works
Nutrient Quality70
Several B-vitamin forms are clearly identified, and biotin is in its biologically active form. Unstated blend proportions and uncertain quality for some other ingredients limit close comparisons.
Ingredient Transparency77
Ingredient amounts and nearly all forms are stated, giving a useful picture of the mix. Missing proportions in six blends and differing thiamin quantities make the exact composition less clear.
Value For Money45
Vitamin B6 provides a clear price strength, while niacin and vitamin B5 are costly for what they supply. Several other ingredient values are uncertain, leaving a mixed picture of the whole formula.
Customer Satisfaction89
Customer ratings are very positive. Feedback from 3,245 ratings gives a broad picture of satisfaction.
Product Focus62
The broad formula links several related functions through B-vitamin nutrition. Benefits are clearest when intake is low, rather than as added energy, sharper thinking or better mood with adequate intake.
- Format
Capsule - Container
- 120 Capsule(s)
- Per serving
- $0.69
- Also available
Coenzyme B-Complex Advanced$26.79- Customer rating
- 4.8 · 3,245 ratings
Goals
Impact
High effect
Vitamin B5 · 76 mgRiboflavin · 37 mgThiamin · 25 mgVitamin B12 · 400 mcg
B vitamins support normal energy metabolism, with B12 and folate particularly relevant to fatigue associated with deficiency-related anaemia. Riboflavin, B5, B6, niacin and vitamin C can also help when low intake contributes to tiredness. These roles do not establish extra energy when intake is adequate. The different vitamin forms and generous amounts do not establish superior fatigue relief.
How this product is rated for Energy
Ingredient fit85
The formula’s relevance depends on its energy-related ingredients and their declared amounts.
Goal fit
The relevant ingredients dominate the formula, though its uses extend beyond energy.
Dose adequacy
The declared amounts provide a partial match to the comparison ranges, with some contributions smaller than others.
Pathways0
The findings identify nutritional support without a separate alertness, exercise or stress-fatigue contribution.
Depth
The findings identify nutritional support without a separate alertness, exercise or stress-fatigue contribution.
Breadth
No additional alertness, exercise-capacity or stress-fatigue route was established.
Evidence81
Vitamin B12 provides the strongest evidence connection here, subject to the population and benefit limits described above.
Evidence strength
Vitamin B12 provides the strongest evidence connection here, subject to the population and benefit limits described above.
Studied preparation
The recognized preparations matched the saved comparison; this does not establish superiority of particular forms.
Formulation logic100
The recognized ingredients have their required support, with no configured conflict identified.
Partner coverage
The recognized ingredients have no missing required partner in these findings.
Conflicts
No configured ingredient conflict was identified.
Effective doses
All recognized ingredients meet the saved minimum amount threshold; that threshold does not prove clinical benefit.
Vitamin B5 Not classified
No linked studies yet.
Impact
High effect
Biotin · 300 mcgNiacin · 53 mgVitamin B12 · 400 mcgRiboflavin · 37 mgThiamin · 25 mgVitamin B5 · 76 mgVitamin B6 · 50 mg
B vitamins help the body use carbohydrate, fat and protein for normal energy production. Extra B vitamins do not establish a faster metabolic rate when intake is adequate.
How this product is rated for Metabolism Support
Ingredient fit77
The formula combines credited metabolic nutrients with differing amounts and, in some cases, ingredients serving other purposes.
Goal fit
Several nutrients receive credit for metabolic roles, alongside ingredients serving other purposes.
Dose adequacy
Declared amounts support varying contributions; a comparison amount does not establish a clinically effective thermogenic dose.
Pathways0
No evaluated energy-expenditure pathway receives a contribution; normal nutrient metabolism is a separate role.
Depth
No evaluated energy-expenditure pathway receives a contribution; normal nutrient metabolism is a separate role.
Breadth
No evaluated pathway reaches the saved coverage benchmark.
Evidence100
Thiamin leads the saved evidence finding, but its normal carbohydrate-metabolism role does not prove extra energy expenditure with adequate intake.
Evidence strength
Thiamin leads the saved evidence finding, but its normal carbohydrate-metabolism role does not prove extra energy expenditure with adequate intake.
Studied preparation
Qualifying ingredients meet the saved preparation criteria; this does not by itself demonstrate a thermogenic benefit.
Formulation logic100
Credited ingredients meet partner requirements and no configured conflicts were found. Their amount thresholds do not establish extra energy expenditure.
Partner coverage
No credited ingredient has an unmet partner requirement in the supplied findings.
Conflicts
No configured ingredient conflict was identified in the supplied facts.
Effective doses
All credited ingredients meet the saved amount threshold, which is a comparison criterion rather than proof of a metabolic-rate effect.
Ingredients
| Ingredient | Amount per serving | Score |
|---|---|---|
Vitamin C (Ascorbic Acid, Calcium Ascorbate, Chromium Ascorbate, Copper Ascorbate, Magnesium Ascorbate, Manganese Ascorbate, Potassium Ascorbate, Zinc Ascorbate) | 60 mg | |
Thiamin (Thiamine Cocarboxylase Chloride, Thiamine Hydrochloride) | 26 mg | |
Riboflavin (Riboflavin 5-Phosphate) | 37 mg | |
Niacin (Inositol Hexaniacinate, Nicotinamide Adenine Dinucleotide) | 53 mg | |
Vitamin B6 (Pyridoxal 5-Phosphate, Pyridoxine Alpha-Ketoglutarate Hydrochloride, Pyridoxine Hydrochloride) | 50 mg | |
Folate ((6S)-5-Methyltetrahydrofolate-Glucosamine Salt) | 360 mcg DFE | |
Vitamin B12 (Methylcobalamin) | 400 mcg | |
Biotin (D-Biotin) | 300 mcg | |
Pantothenic Acid (Calcium D-Pantothenate, Pantethine) | 76 mg | |
Benfotiamine | 25 mg | |
LifePQQ (Pyrroloquinoline Quinone Disodium Salt) | 5 mg | |
Nicotinamide Adenine Dinucleotide | 500 mcg |
Vitamin B6 (Pyridoxal 5-Phosphate, Pyridoxine Alpha-Ketoglutarate Hydrochloride, Pyridoxine Hydrochloride) · 50 mg OverallScore71
A serving provides 50 mg of vitamin B6, exceeding the European adult daily upper limit. The B6 sources are identified, although their proportions are unknown.
How this ingredient is rated
Ingredient Form & Label Quality100
The B6 sources are identified, but their individual proportions are unknown.
Vitamin B6 Form Identification
The B6 sources are pyridoxal 5-phosphate, pyridoxine alpha-ketoglutarate hydrochloride and pyridoxine hydrochloride; their individual proportions are unknown.
Clean Label and Excipient Purity
No artificial dyes, titanium dioxide or talc were flagged in the saved additive evaluation.
Dose, Safety & Label Transparency37
A serving supplies 50 mg of B6, more than the European adult daily upper limit. The B6 source is identified.
Vitamin B6 Dose & Safety Policy
One serving provides 50 mg of B6, exceeding the European adult daily upper limit; total daily intake can be higher.
Label Transparency
The chemical source of B6 is identified in the saved information.
Value83
At about $0.014 per mg of vitamin B6, the cost is relatively low in the B6 comparison.
Vitamin B6 Price Efficiency
At about $0.014 per mg of vitamin B6, the cost is relatively low in the B6 comparison.
Each serving lists 26 mg of thiamin and 25 mg of benfotiamine, the latter being a compound amount rather than additional confirmed thiamin. The named sources include thiamine cocarboxylase chloride, thiamine hydrochloride and benfotiamine, but their contributions to the thiamin amount are not fully known.
How this ingredient is rated
Active Ingredient Quality & Bioavailability74
The named sources are thiamine cocarboxylase chloride, thiamine hydrochloride and benfotiamine, with their complete proportions unknown. The evaluation does not flag the specified artificial colors or sweeteners in the saved information.
Thiamin Chemical Form
The named sources are thiamine cocarboxylase chloride, thiamine hydrochloride and benfotiamine; their proportions are not fully known.
Excipient Purity
The evaluation does not flag the specified artificial colors or sweeteners in the saved information.
Dose, Safety & Label Transparency72
The serving supplies 26 mg of thiamin, which the evaluation considers a moderate amount. The amount is separately specified.
Thiamin Dosage Potency
The declared 26 mg of thiamin is considered a moderate amount in the evaluation.
Label Transparency & Proprietary Blends
The amount is stated as 26 mg of thiamin per serving.
Value40
The normalized cost is about $2.69 per 100 mg of thiamin, in the higher band used for this evaluation. It reflects the cost of the whole product, including its other contents.
Price per Declared Dose
The cost is about $2.69 per 100 mg of thiamin, based on whole-product pricing; the evaluation places it in the higher band.
A serving provides 53 mg niacin from inositol hexanicotinate and nicotinamide adenine dinucleotide (NAD). Their individual contributions are not established in the available information.
How this ingredient is rated
Active Ingredient Quality & Bioavailability54
The recorded B3 sources are inositol hexanicotinate and nicotinamide adenine dinucleotide (NAD); their individual contributions are not established.
Niacin Form & Goal Alignment
Inositol hexanicotinate and NAD are named in an energy-related product context, but their source amounts are not established.
Precursor Source Quality
Both compounds are named; their individual amounts and any separate NR source are not established.
Dose, Safety & Label Transparency67
The serving records 53 mg niacin from two named forms, with their individual amounts unspecified.
Clarity of Chemical Form
Both source forms are identified, but the available information does not establish their individual shares.
Form-Specific Dosage Efficacy
The 53 mg niacin amount is the combined total, not a separate amount for each named source.
Flush Risk & Safety Labeling
A product-wide no-flush claim and a complete flushing profile for this mixture are not established in the available information.
Value20
The whole-product serving costs about $0.70.
Price Per Effective Serving
The whole-product serving costs about $0.70.
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Sources
Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.
- Physicochemical properties of and volatile compounds in riboflavin fortified cloudy apple juice; study of its effect on job fatigue among Egyptian construction workers.
- Vitamin B status in patients with chronic fatigue syndrome.
- B-vitamins, related vitamers, and metabolites in patients with quiescent inflammatory bowel disease and chronic fatigue treated with high dose oral thiamine.
- Metabolic features of chronic fatigue syndrome.
- Effectiveness of Riboflavin in Inherited Metabolic Diseases: A Systematic Review
- Influence of thiamin supplementation on the health and general well-being of an elderly Irish population with marginal thiamin deficiency.
- Randomised clinical trial: high-dose oral thiamine versus placebo for chronic fatigue in patients with quiescent inflammatory bowel disease.
- Dietary reference values for thiamin.
- Effects of thiamine supplementation on exercise-induced fatigue.
- Long-term maintenance treatment with 300 mg thiamine for fatigue in patients with inflammatory bowel disease: results from an open-label extension of the TARIF study.
- A new perspective on vitamin B12 deficiency in rheumatology: a case-based review.
- Effects of Vitamin B12 Supplementation on Cognitive Function, Depressive Symptoms, and Fatigue: A Systematic Review, Meta-Analysis, and Meta-Regression.
- Patients' experiences with methylcobalamin injections in amyotrophic lateral sclerosis.
- Cobalamin deficiency: clinical picture and radiological findings.
- Vitamin B12 Deficiency: Common Questions and Answers.
- Biotin and contribution to normal energy-yielding metabolism: evaluation of a health claim pursuant to Article 14 of Regulation (EC) No 1924/2006.
- Pregnancy and lactation alter biomarkers of biotin metabolism in women consuming a controlled diet.
- Survey of the effect of biotin on glycemic control and plasma lipid concentrations in type 1 diabetic patients in kermanshah in iran (2008-2009)
- Chromium picolinate and biotin combination improves glucose metabolism in treated, uncontrolled overweight to obese patients with type 2 diabetes
- Biotin supplementation reduces plasma triacylglycerol and VLDL in type 2 diabetic patients and in nondiabetic subjects with hypertriglyceridemia