Bone Restore with Vitamin K2

Bone Restore with Vitamin K2

Life Extension4.8 (10,642 ratings)
Format:Capsule Quantity: 120 Capsule(s) · 30 servings
Goals

Product analysis

66 out of 100

Bone Restore with Vitamin K2 combines calcium with vitamins D and K to help fill nutritional gaps relevant to bone health. Its magnesium uses a less readily absorbed form, which matters if magnesium is a main reason for choosing it.

AI assessment of the formula, label and price. How scoring works

Nutrient Quality55

Calcium, vitamin K and boron use favorable forms, while magnesium oxide has limited absorption potential. The horsetail-derived silicon is less clearly characterized, leaving its absorption uncertain.

Ingredient Transparency80

All listed nutrient amounts and forms are disclosed, making the formula straightforward to identify. The split between the calcium sources is missing, so their individual contributions remain unclear.

Value For Money45

Vitamin K compares favorably on price, while calcium sits in the middle range. Magnesium and boron are less appealing on value, with several other nutrient comparisons uncertain.

Customer Satisfaction93

Customer feedback is strongly positive across a large number of reviews. The volume gives a broad picture of satisfaction without establishing bone or heart benefits.

Product Focus69

Bone nutrition is the clearest purpose, especially when mineral intake is low. The wider set of intended uses has more limited or conditional support.

Format
Capsule
Container
120 Capsule(s)
Per serving
$0.59
Customer rating
4.8 · 10,642 ratings
Report analysis

Goals

Bone Health
Impact
Highest effect
B+ Ingredient FitA+ PathwaysA+ EvidenceA+ Formulation Logic
Vitamin K · 200 mcgMagnesium · 300 mgCalcium · 700 mgVitamin D · 25 mcgManganese · 1 mgBoron · 3 mgZinc · 2 mg

Calcium and magnesium help fill mineral intake gaps, while vitamin D supports calcium absorption and normal mineralization. MK-7 vitamin K adds a connection to bone-protein activation, with limited bone-density findings in postmenopausal women rather than established general fracture prevention. The 200 mcg MK-7 serving is close to the amount used in one long-term trial. Horsetail-derived silicon does not establish equivalence to the choline-stabilized preparation behind the supplied exploratory findings.

How this product is rated for Bone Health

Ingredient fit81

The ingredients are closely focused on bone-related roles, with substantial but uneven amount support. Zinc is too low to be counted.
Goal fit
All counted ingredients relate to the bone focus, although the product is linked to other goals too.
Dose adequacy
Calcium, magnesium, vitamin D and MK-7 supply meaningful amounts; the supporting ingredients contribute unevenly.

Pathways100

The combination covers mineral supply, calcium regulation and bone-protein activation in the supplied findings.
Depth
Bone mineral supply is fully covered through the supplied calcium and magnesium contributions.
Breadth
Mineral supply, calcium regulation and bone-protein activation reach the coverage threshold.

Evidence99

Calcium supplies the strongest saved evidence foundation. Silicon's horsetail source differs from the specific preparation in the exploratory bone studies.
Evidence strength
Calcium leads the saved evidence ranking, chiefly for its nutritional mineral role.
Studied preparation
Most counted preparations are recognized; silicon does not match the specifically studied preparation.

Formulation logic100

The counted ingredients have their designated partners or can contribute independently. No evaluated conflict was found.
Partner coverage
All designated partner requirements are met.
Conflicts
No evaluated ingredient conflict was identified.
Effective doses
All seven counted ingredients reach the qualifying amount threshold; zinc is below it.
Study evidence
Boron Supportive 5 studies
Calcium Supportive 144 studies
Magnesium Supportive 48 studies
Manganese Adverse 12 studies
Silicon Supportive 13 studies
Vitamin D Supportive 202 studies
Vitamin K Supportive 78 studies
Zinc Supportive 33 studies
Impact
Highest effect
B Ingredient FitB+ PathwaysA- EvidenceA+ Formulation Logic
Vitamin D · 25 mcgMagnesium · 300 mgVitamin K · 200 mcgBoron · 3 mgZinc · 2 mg

Magnesium can make a substantial contribution to a dietary gap; its amount does not establish an extra energy, sleep or stress benefit. Calcium helps fill low intake that can otherwise contribute to bone loss. Vitamin D contributes to ordinary nutritional needs; higher quantities do not establish added general-health benefit.

How this product is rated for Everyday Health

Ingredient fit76

Relevant nutrients share the formula with ingredients for broader purposes, reducing its focus on the assessed general-health roles. Amount support is partial.
Goal fit
Relevant nutrients share the formula with ingredients for broader purposes, reducing its focus on the assessed general-health roles.
Dose adequacy
Amount support is partial under the saved comparison criteria; small or unresolved quantities limit the contribution assigned.

Pathways80

The main saved connection is energy metabolism cofactors. 2 assessed pathways meet the saved coverage requirement, spanning several nutritional roles rather than proving multiple clinical benefits.
Depth
The strongest saved connection is energy metabolism cofactors; this describes a supported ingredient role rather than a measured health improvement.
Breadth
2 assessed pathways meet the saved coverage requirement, spanning several nutritional roles rather than proving multiple clinical benefits.

Evidence86

Magnesium supplies the strongest included support in the saved findings; the scientific context confines expectations to nutritional contribution or narrowly studied outcomes.
Evidence strength
Magnesium supplies the strongest included support in the saved findings; the scientific context confines expectations to nutritional contribution or narrowly studied outcomes.
Studied preparation
The saved findings accept the included preparations; no chemical-form or delivery advantage follows from that match.

Formulation logic100

No required ingredient partner is missing in the saved findings; this does not establish an added benefit from combining ingredients. No configured ingredient conflict was identified in the supplied findings.
Partner coverage
No required ingredient partner is missing in the saved findings; this does not establish an added benefit from combining ingredients.
Conflicts
No configured ingredient conflict was identified in the supplied findings.
Effective doses
All counted ingredients meet the saved minimum amount criterion; this does not make it a proven clinical threshold.
Study evidence
Boron Supportive 6 studies
Magnesium Supportive 114 studies
Vitamin D Supportive 115 studies
Vitamin K Supportive 34 studies
Zinc Supportive 60 studies
Longevity
Impact
High effect
C+ Ingredient FitF PathwaysA EvidenceA+ Formulation Logic
Magnesium · 300 mgVitamin K · 200 mcgVitamin D · 25 mcg

Vitamin D can support muscle function when deficiency contributes to weakness, with no established extra benefit when status is adequate. MK-7 has selected arterial-stiffness findings in postmenopausal women using identified MenaQ7, but this vitamin K2 declaration does not establish that preparation. Magnesium's supplied functional trial was limited to exercising older women, especially those with low intake; it does not establish general preservation of aging-related function.

How this product is rated for Longevity

Ingredient fit66

Vitamin D, vitamin K2 and magnesium provide several nutritional and vascular connections.
Goal fit
Vitamin D, vitamin K2 and magnesium provide several nutritional and vascular connections.
Dose adequacy
The included amounts provide mixed comparison coverage; zinc falls below the saved minimum.

Pathways19

The saved findings show a limited arterial-calcification contribution.
Depth
The saved findings show a limited arterial-calcification contribution.
Breadth
No route reaches substantial coverage in the saved findings.

Evidence94

Magnesium leads the saved evidence finding, with limited applicability from its older-women exercise trial.
Evidence strength
Magnesium leads the saved evidence finding, with limited applicability from its older-women exercise trial.
Studied preparation
Vitamin K2 is unidentified relative to MenaQ7, and boron lacks studied-preparation support in the saved finding.

Formulation logic100

The included ingredients need no missing partner, and no configured ingredient conflict was found.
Partner coverage
The included ingredients work independently or have their required partner.
Conflicts
No configured ingredient conflict was found.
Effective doses
All included ingredients meet the saved minimum amount comparison; this does not prove a clinically effective anti-aging dose.
Study evidence
Boron Not classified

No linked studies yet.

Magnesium Supportive 12 studies
Vitamin D Supportive 50 studies
Vitamin K Supportive 27 studies
Zinc Supportive 10 studies
Impact
High effect
C Ingredient FitB PathwaysA- EvidenceA+ Formulation Logic
Vitamin K · 200 mcgMagnesium · 300 mgVitamin D · 25 mcg

Magnesium contributes to blood-pressure regulation, with small and inconsistent study results. MK-7 has limited evidence for arterial-stiffness changes in postmenopausal women, particularly those with greater baseline stiffness. Vitamin D does not add established cardiovascular prevention benefit, and the combination does not establish an additional effect.

How this product is rated for Heart Health

Ingredient fit63

Heart-related ingredients sit within a broader formula with other active ingredients. The relevant declared amounts provide substantial but incomplete coverage of the saved exposure comparison.
Goal fit
Heart-related ingredients sit within a broader formula with other active ingredients.
Dose adequacy
The relevant declared amounts provide substantial but incomplete coverage of the saved exposure comparison.

Pathways78

The strongest saved connection is to the arterial-stiffness category. Coverage across other heart-related roles is limited.
Depth
The strongest saved connection is to the arterial-stiffness category.
Breadth
The broader saved findings cover blood-pressure and vascular-tone support, the arterial-stiffness category. .

Evidence89

Magnesium leads the saved evidence finding. Accepted preparation matches do not remove the ingredient-specific limitations described above.
Evidence strength
Magnesium provides the leading evidence contribution in the saved comparison; its clinical limitations still apply.
Studied preparation
The saved finding accepts the preparations used for its included ingredients; it does not establish that every labelled preparation matches a clinical trial.

Formulation logic100

The saved checks find no missing required partner or configured conflict. The included amounts pass the minimum comparison screen.
Partner coverage
The included ingredients do not lack a required partner under the saved finding; this does not establish added benefit from combining them.
Conflicts
No configured ingredient conflict was triggered by the supplied facts.
Effective doses
All ingredients included in this amount screen meet its minimum comparison level; that level is not a proven effective dose.
Study evidence
Magnesium Supportive 158 studies
Vitamin D Mixed 164 studies
Vitamin K Mixed 62 studies
Cardiovascular Support
Impact
High effect
C Ingredient FitB+ PathwaysB EvidenceA+ Formulation Logic
Vitamin K · 200 mcgMagnesium · 300 mgVitamin D · 25 mcg

Magnesium may support arterial stiffness and blood-pressure regulation, particularly with low status or elevated blood pressure, but trial findings are mixed. MK-7 has limited support for arterial-stiffness measures in postmenopausal women. Vitamin D can correct deficiency, without established cardiovascular-event prevention from routine supplementation.

How this product is rated for Cardiovascular Support

Ingredient fit63

Magnesium, Vitamin K, Vitamin D account for the relevant ingredient roles. Their serving amounts give partial coverage of the comparison ranges.
Goal fit
Magnesium, Vitamin K, Vitamin D provide the relevant connection; the formula also includes ingredients outside these supported roles.
Dose adequacy
The relevant serving amounts provide only partial exposure relative to the saved comparison ranges.

Pathways80

The main connection is arterial calcification control. Coverage extends to vascular tone and sodium balance, arterial calcification control.
Depth
The strongest connection is arterial calcification control, rather than broad cardiovascular outcomes.
Breadth
The supported coverage is concentrated in vascular tone and sodium balance, arterial calcification control.

Evidence79

Magnesium leads the supplied evidence among qualifying ingredients. The accepted preparations do not remove the limits of the underlying findings.
Evidence strength
Magnesium provides the strongest supplied evidence among the qualifying ingredients, with the population and outcome limits described above.
Studied preparation
The qualifying preparations match those accepted in the supplied comparison; this does not establish superior benefit for their forms.

Formulation logic100

The relevant ingredients need no missing partner and no listed conflict was found. Their qualifying amounts do not establish added benefit from combining them.
Partner coverage
The relevant ingredients can contribute independently or have the required partner; no extra combined benefit is established.
Conflicts
No listed ingredient conflict was found in the supplied checks.
Effective doses
The qualifying ingredients meet the saved minimum amount criterion, which is not a proven benefit threshold.
Study evidence
Magnesium Supportive 123 studies
Vitamin D Mixed 170 studies
Vitamin K Supportive 40 studies
Joint Health
Impact
Moderate effect
B- Ingredient FitF PathwaysC+ EvidenceA+ Formulation Logic

Magnesium, vitamin D and vitamin K provide general nutritional support, while manganese is involved in enzymes that help build cartilage components. These normal roles do not imply that additional supplementation improves joint comfort when nutritional needs are already met.

How this product is rated for Joint Health

Ingredient fit73

Joint-related ingredients share the formula with ingredients aimed at other health needs. The included amounts provide partial support against the saved dose benchmarks.
Goal fit
Joint-related ingredients share the formula with ingredients aimed at other health needs.
Dose adequacy
The included amounts provide partial support against the saved dose benchmarks.

Pathways0

No assessed joint mechanism has meaningful coverage in the saved findings. None of the three target mechanisms reaches the saved coverage threshold.
Depth
No assessed joint mechanism has meaningful coverage in the saved findings.
Breadth
None of the three target mechanisms reaches the saved coverage threshold.

Evidence65

Magnesium provides the strongest saved evidence rating here; that rating should not be read as proof of standalone joint-comfort benefit. The saved assessment recognizes the preparations of all ingredients included at qualifying amounts.
Evidence strength
Magnesium provides the strongest saved evidence rating here; that rating should not be read as proof of standalone joint-comfort benefit.
Studied preparation
The saved assessment recognizes the preparations of all ingredients included at qualifying amounts.

Formulation logic100

No required ingredient partner is missing in the saved findings. No configured ingredient conflict was found in the saved assessment. All ingredients included in this finding reach the saved minimum dose threshold.
Partner coverage
No required ingredient partner is missing in the saved findings.
Conflicts
No configured ingredient conflict was found in the saved assessment.
Effective doses
All ingredients included in this finding reach the saved minimum dose threshold.
Study evidence
Boron Supportive 3 studies
Magnesium Supportive 18 studies
Manganese Supportive 3 studies
Silicon Mixed 4 studies
Vitamin D Supportive 111 studies
Vitamin K Disputed 14 studies
Zinc Supportive 7 studies

Ingredients

IngredientAmount per servingScore
Vitamin D3 (Cholecalciferol)
25 mcg
Vitamin K2 (Menaquinone-7)
200 mcg 96
Calcium (Calcium Bisglycinate Chelate, Calcium Fructoborate, Dicalcium Malate)
700 mg 76
Magnesium (Magnesium Oxide)
300 mg 42
Zinc (Zinc Amino Acid Chelate)
2 mg
Manganese (Manganese Amino Acid Chelate)
1 mg
Silicon (Horsetail extract)
5 mg 59
Boron (Calcium Fructoborate)
3 mg 80
Gluten Free Adults 18–50
Report overview
A+ Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyB+ Value
A serving lists 200 mcg of vitamin K2 as trans-MK-7. A whole-product serving costs about $0.60.
How this ingredient is rated

Active Ingredient Quality & Bioavailability100

The vitamin K2 is identified as trans-MK-7.
Vitamin K Form (MK-7 vs. MK-4 vs. K1)
The identified form is vitamin K2 as trans-MK-7.
MK-7 Isomer Disclosure
The MK-7 source is identified as trans-MK-7.

Dose, Safety & Label Transparency100

The serving individually lists 200 mcg of MK-7.
Vitamin K2 (MK-7) Dosage Efficacy
The serving lists 200 mcg of MK-7.
Form and Subtype Transparency
The amount and subtype are identified as 200 mcg of trans-MK-7 per serving.

Value80

A whole-product serving costs about $0.60; the price covers the whole product, not vitamin K alone.
Price per Effective MK-7 Serving
A whole-product serving costs about $0.60; the price covers the whole product, not vitamin K alone.
A- Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyF Value
A serving supplies 3 mg boron as calcium fructoborate. The whole-product serving costs about $0.60.
How this ingredient is rated

Active Ingredient Quality & Bioavailability85

Boron is supplied as calcium fructoborate, a form rated favorably in the evaluation.
Boron Form & Bioavailability
Calcium Fructoborate is rated favorably in the form evaluation.
Trademarked & High-Purity Sources
The saved evaluation does not identify a recognized branded source or a qualifying purity marker.

Dose, Safety & Label Transparency100

The serving states 3 mg elemental boron and names its source form.
Elemental Dose Transparency
The saved label facts give 3 mg elemental boron per serving and identify the source form.
Dosage Efficacy & Safety Margin
A serving provides 3 mg boron, an amount the evaluation rates favorably.

Value30

The scaled whole-product cost is about $0.60 per 3 mg boron.
Price per 3mg Elemental Boron
The whole-product cost scales to about $0.60 per 3 mg boron; it includes all ingredients in the product.
A+ Active Ingredient Quality & BioavailabilityC Dose, Safety & Label TransparencyD+ Value
A serving provides 700 mg of elemental calcium from calcium bisglycinate, calcium fructoborate and dicalcium malate. The evaluation cautions that absorption may be less efficient at this serving amount.
How this ingredient is rated

Active Ingredient Quality & Bioavailability100

Calcium is recorded from calcium bisglycinate, calcium fructoborate and dicalcium malate; the stated amount is elemental calcium.
Calcium Form & Absorption Potential
The recorded sources are calcium bisglycinate, calcium fructoborate and dicalcium malate; their individual proportions are not established.
Elemental Calcium Transparency
The recorded 700 mg per serving refers to calcium itself, rather than the weight of a source compound.

Dose, Safety & Label Transparency64

The serving provides 700 mg of elemental calcium. The evaluation cautions that absorption may be less efficient at this amount. No configured artificial additive or flow agent was identified; the sugar amount is not recorded.
Absorption-Optimized Serving Dose
A serving provides 700 mg of calcium; the evaluation cautions that absorption may be less efficient at this amount.
Formulation Purity & Additives
No configured artificial additive or flow agent was identified; the sugar amount is not recorded.

Value50

The whole product costs about $0.60 per serving, a moderate serving price in the evaluation.
Price Per Serving Efficiency
A whole-product serving costs about $0.60; the comparison uses that serving price.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. [Comparative study of the urinary excretion of boron, calcium, magnesium and phosphorus in postmenopausal women with and without osteoporosis].
    José Ramón V; Mora Mora M; Marino Alarcón O; Hernández G; Josefina Linares L; Urdaneta Romero H; Arévalo González E · Investigacion clinica · 2013
    Case-control study45 participantsBone Health forBoron
  2. Effect of dietary boron on mineral, estrogen, and testosterone metabolism in postmenopausal women.
    Nielsen FH; Hunt CD; Mullen LM; Hunt JR · FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 1987
    Single-arm trial12 participantsBone Health forBoron
  3. The relationship between boron and magnesium status and bone mineral density in the human: a review.
    Volpe SL; Taper LJ; Meacham S · Magnesium research · 1994
    Narrative reviewBone Health forBoron
  4. Effects of boron supplementation on bone mineral density and dietary, blood, and urinary calcium, phosphorus, magnesium, and boron in female athletes.
    Meacham SL; Taper LJ; Volpe SL · Environmental health perspectives · 1995
    Randomized trial28 participantsBone Health forBoron
  5. Metabolic responses of postmenopausal women to supplemental dietary boron and aluminum during usual and low magnesium intake: boron, calcium, and magnesium absorption and retention and blood mineral concentrations
    C D Hunt, J L Herbel, F H Nielsen · The American Journal of Clinical Nutrition · 1997
    Non-randomized trial11 participantsBone Health forBoron
  6. What is the impact of daily oral supplementation of vitamin D3 (cholecalciferol) plus calcium on the incidence of hip fracture in older people? A systematic review and meta-analysis.
    Manoj P; Derwin R; George S · International journal of older people nursing · 2023
    Meta-analysis12,620 participants7 studies pooledBone Health forCalcium
  7. Calcium supplementation prevents seasonal bone loss and changes in biochemical markers of bone turnover in elderly New England women: a randomized placebo-controlled trial.
    Storm D; Eslin R; Porter ES; Musgrave K; Vereault D; Patton C; Kessenich C; Mohan S; Chen T; Holick MF; Rosen CJ · The Journal of clinical endocrinology and metabolism · 1998
    Randomized trial60 participantsBone Health forCalcium
  8. The effects of calcium supplementation (milk powder or tablets) and exercise on bone density in postmenopausal women.
    Prince R; Devine A; Dick I; Criddle A; Kerr D; Kent N; Price R; Randell A · Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 1995
    Randomized trial168 participantsBone Health forCalcium
  9. The efficacy of calcium supplementation alone in elderly Thai women over a 2-year period: a randomized controlled trial.
    Rajatanavin R; Chailurkit L; Saetung S; Thakkinstian A; Nimitphong H · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2014
    Randomized trial404 participantsBone Health forCalcium
  10. Calcium-enriched foods and bone mass growth in prepubertal girls: a randomized, double-blind, placebo-controlled trial.
    Bonjour JP; Carrie AL; Ferrari S; Clavien H; Slosman D; Theintz G; Rizzoli R · The Journal of clinical investigation · 1997
    Randomized trial149 participantsBone Health forCalcium
  11. Association between Serum Magnesium and Fractures: A Systematic Review and Meta-Analysis of Observational Studies.
    Dominguez LJ; Veronese N; Ciriminna S; Pérez-Albela JL; Vásquez-López VF; Rodas-Regalado S; Di Bella G; Parisi A; Tagliaferri F; Barbagallo M · Nutrients · 2023
    Meta-analysis119,755 participants4 studies pooledBone Health forMagnesium
  12. Bioabsorbable Magnesium-Based Materials Potential and Safety in Bone Surgery: A Systematic Review.
    Hung CH; Kwok YC; Yip J; Wong HH; Leung YY · Craniomaxillofacial trauma & reconstruction · 2025
    Systematic review386 participants8 studies pooledBone Health forMagnesium
  13. Vascularized bone grafting fixed by biodegradable magnesium screw for treating osteonecrosis of the femoral head.
    Zhao D; Huang S; Lu F; Wang B; Yang L; Qin L; Yang K; Li Y; Li W; Wang W; Tian S; Zhang X; Gao W; Wang Z; Zhang Y; Xie X; Wang J; Li J · Biomaterials · 2016
    Randomized trial48 participantsBone Health forMagnesium
  14. An update on magnesium and bone health.
    Rondanelli M; Faliva MA; Tartara A; Gasparri C; Perna S; Infantino V; Riva A; Petrangolini G; Peroni G · Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2022
    Narrative reviewBone Health forMagnesium
  15. Sex-specific differences in the association of magnesium intake with femoral neck bone mineral density among older adults.
    Wang B; Tan X; Yao X; Zhu Z · Endocrine connections · 2025
    Cross-sectional study1,343 participantsBone Health forMagnesium
  16. Risk of Environmental Chemicals on Bone Fractures Is Independent of Low Bone Mass in US Adults: Insights from 2017 to 2018 NHANES.
    Ling R; Ai Y; Chen C; Zhang J; Zou Z; Cheng S; Li C; Li X; Wang B · Metabolites · 2023
    Cross-sectional study2,640 participantsBone Health forManganese
  17. The Manganese-Bone Connection: Investigating the Role of Manganese in Bone Health.
    Taskozhina G; Batyrova G; Umarova G; Issanguzhina Z; Kereyeva N · Journal of clinical medicine · 2024
    Narrative reviewBone Health forManganese
  18. Associations of multiple metals with bone mineral density: A population-based study in US adults.
    Wei MH; Cui Y; Zhou HL; Song WJ; Di DS; Zhang RY; Huang Q; Liu JA; Wang Q · Chemosphere · 2021
    Cross-sectional studyBone Health forManganese
  19. Sex-specific associations of urinary mixed-metal concentrations with femoral bone mineral density among older people: an NHANES (2017-2020) analysis.
    Li H; Li G; Yi M; Zhou J; Deng Y; Huang Y; He S; Meng X; Liu L · Frontiers in public health · 2024
    Cross-sectional study31 participantsBone Health forManganese
  20. Relationship between blood manganese and bone mineral density and bone mineral content in adults: A population-based cross-sectional study.
    Wang C; Zhu Y; Long H; Ou M; Zhao S · PloS one · 2022
    Cross-sectional study9,732 participantsBone Health forManganese