Product Image

Male Response

Source Naturals
4.2
★ ★ ★ ★ ★
(337 ratings)
Copper 1 mg
Vitamin B6 25 mg
Selenium 150 mcg
Vitamin B5 50 mg
Stinging Nettle 60 mg
Eleuthero 200 mg
Tribulus 500 mg
Product Image
Score59
Zinc, selenium, ashwagandha, nettle, saw palmetto, tribulus, eleuthero, and other botanicals create a clear male-vitality formula, but standardization and effective dosing are inconsistent. Yohimbe bark extract may raise heart rate, blood pressure, or anxiety and poses added risk with cardiovascular conditions, stimulants, antidepressants, or blood-pressure medicines.
How scoring works
Quantity:90 Tablet(s) • (30 servings)
Goals:

Score 59

Zinc, selenium, ashwagandha, nettle, saw palmetto, tribulus, eleuthero, and other botanicals create a clear male-vitality formula, but standardization and effective dosing are inconsistent. Yohimbe bark extract may raise heart rate, blood pressure, or anxiety and poses added risk with cardiovascular conditions, stimulants, antidepressants, or blood-pressure medicines.
How scoring works
$23.79($0.79 per serving)
iHerb
$ 23.79
Vitacost
$ 23.79
Report prices

Analysis

Zinc, selenium, ashwagandha, nettle, saw palmetto, tribulus, eleuthero, and other botanicals create a clear male-vitality formula, but standardization and effective dosing are inconsistent. Yohimbe bark extract may raise heart rate, blood pressure, or anxiety and poses added risk with cardiovascular conditions, stimulants, antidepressants, or blood-pressure medicines.

Copper sebacate is a well-absorbed organic form. 1 mg meets the daily allowance but remains below the collection median.

Saw palmetto, zinc, selenium, copper, vitamin E, and ashwagandha create a plausible male hair-support profile centered on androgen balance, mineral status, and oxidative protection. Saw palmetto and ashwagandha lack clear standardization, which makes their active potency uncertain.

Who is it for
  • Adults focused on hair health
  • Adults focused on testosterone support
  • Adults focused on cognitive support
Best for
  • Copper supplementation
  • Vitamin B6 supplementation
  • Selenium supplementation

Pros

  • Provides a disclosed 250.00mg of ashwagandha root extract
  • Provides a disclosed 200.00mg of saw palmetto
  • Provides a disclosed 225.00mg of yohimbe bark extract

Cons

  • Yohimbe creates meaningful cardiovascular and anxiety risk
  • Botanical standardization is inconsistent
  • Several actives may be too lightly dosed for their intended role

Warnings

  • Yohimbe may raise heart rate, blood pressure, or anxiety and is risky with cardiovascular disease.
  • Do not combine yohimbe casually with stimulants, antidepressants, or blood-pressure medicines.
  • Saw palmetto and nettle can complicate interpretation of urinary symptoms that warrant medical assessment.

Nutrient quality

57 Moderate impact

Zinc methionine and selenomethionine are useful forms, while most botanicals lack active standardization. Several herbs are present at material amounts, but arginine is too low for a strong blood-flow effect and yohimbe potency is unknown.

.

Ingredient transparency

71 High impact

Amounts are listed, but yohimbine yield and most botanical standardizations are missing. Complete non-active ingredient details are not included in the supplied label data.

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Customer satisfaction

62 Moderate impact

The supplied average rating provides limited high-level context. Detailed firsthand feedback is unavailable, so recurring complaints and purpose fit cannot be assessed.

.

Value for money

44 Lower impact

The premium serving cost is not well supported by uneven evidence and missing standardization. Many material doses are present, but uncertain potency and overlap reduce practical value.

.
Report analysis

Goals

Hair Health
Hair Health
Impact
Moderate effect
C+ Goal FitC Strength of SupportC CoverageC Formula Quality
Zinc · 15 mg

Saw palmetto, zinc, selenium, copper, vitamin E, and ashwagandha create a plausible male hair-support profile centered on androgen balance, mineral status, and oxidative protection. Saw palmetto and ashwagandha lack clear standardization, which makes their active potency uncertain.

The formula has more direct hormonal relevance than a basic multivitamin but does not supply biotin, iron, sulfur amino acids, or structural protein. Yohimbe may raise heart rate or blood pressure and makes the serving unsuitable for some people with cardiovascular conditions or stimulant use.

Study evidence
Ashwagandha Supportive 2 studies
Copper Adverse 4 studies
Saw Palmetto Supportive 5 studies
Selenium Disputed 7 studies
Vitamin E No effect 3 studies
Zinc Supportive 22 studies
Testosterone Support
Testosterone Support
Impact
Moderate effect
C+ Goal FitD+ Strength of SupportC+ CoverageD+ Formula Quality
Zinc · 15 mgAshwagandha · 250 mg

Ashwagandha, zinc, stinging nettle, selenium, and several male-health botanicals give the formula clear relevance to hormone and stress pathways. Evidence is strongest for ashwagandha and adequate zinc status, while tribulus and several libido herbs have less consistent support for testosterone.

The disclosed amounts are helpful, but ashwagandha lacks a withanolide standard and the ginger and nettle doses are modest. Yohimbe at 225 mg may raise heart rate or blood pressure, especially for people with cardiovascular conditions or those using stimulants.

Study evidence
Ashwagandha Supportive 17 studies
Ginger Not classified

No linked studies yet.

Selenium No effect 16 studies
Tribulus Disputed 13 studies
Zinc Disputed 7 studies
Cognitive Support
Cognitive Support
Impact
Moderate effect
C Goal FitC- Strength of SupportC+ CoverageF Formula Quality
Vitamin B6 · 25 mgAshwagandha · 250 mg

Ashwagandha, Eleuthero, ginkgo, and Panax ginseng may support stress resilience, mental stamina, and circulation. Several are supplied at plausible supporting amounts.

The libido-oriented formula includes many unrelated botanicals and does not standardize its main cognitive extracts. Yohimbe may raise heart rate or blood pressure and can be unsuitable with cardiovascular conditions or stimulant use.

Study evidence
Ashwagandha Supportive 17 studies
Eleuthero No effect 1 study
Ginkgo Supportive 87 studies
Immunity
Immunity
Impact
Moderate effect
D+ Goal FitB- Strength of SupportD+ CoverageF Formula Quality
Zinc · 15 mgSelenium · 150 mcg

Zinc and selenium provide direct immune support, while eleuthero and several adaptogens may help resilience under stress. The product’s primary purpose is male sexual and vitality support rather than immune health.

Yohimbe can raise heart rate and blood pressure and may interact with stimulant, blood-pressure, or psychiatric medicines. The crowded botanical formula also lacks standardization details for many extracts, limiting confidence in immune relevance.

Study evidence
Eleuthero Supportive 1 study
Ginger Not classified

No linked studies yet.

Selenium Mixed 37 studies
Zinc Supportive 73 studies
General Health
General Health
Impact
Moderate effect
D+ Goal FitC- Strength of SupportC- CoverageD Formula Quality
Selenium · 150 mcgAshwagandha · 250 mgZinc · 15 mg

A few ingredients support stress resilience and antioxidant function, but the formula is mainly aimed at male sexual performance. Ashwagandha, zinc, and selenium provide the clearest connection to broader wellness.

Many botanicals lack standardization, and the wide stimulant-like blend offers uncertain general-health value. Yohimbe bark extract may raise heart rate or blood pressure, especially for people with cardiovascular conditions or those using stimulants.

Study evidence
Ashwagandha Supportive 31 studies
Selenium Supportive 70 studies
Zinc Supportive 60 studies

Ingredients

IngredientAmount per serving
Calories
10 Calorie(s)
Total Carbohydrates
1 Gram(s)
Vitamin E (Vitamin E Succinate)
 100 IU
Vitamin B6 (Pyridoxine Hydrochloride)
 25 mg
Pantothenic Acid (Calcium D-Pantothenate)
 50 mg
Zinc (OptiZinc)
 15 mg
Selenium (L-Selenomethionine, Sodium Selenite)
 150 mcg
Copper (Copper Sebacate)
 1 mg
Sodium
10 mg
Tribulus fruit extract
500 mg
Maca
300 mg
Epimedium aerial parts extract (Flavonoids)
 300 mg
L-Arginine (L-Arginine Pyroglutamate)
 300 mg
Ashwagandha Root Extract
250 mg
Yohimbe Bark Extract
225 mg
Asian Ginseng root extract
210 mg
Oat tops extract
200 mg
Damiana
200 mg
Saw Palmetto
200 mg
Sarsaparilla
200 mg
Eleuthero Root Extract
200 mg
Ginkgo leaf extract
60 mg
Stinging Nettle Root Extract
60 mg
Ginger
60 mg
Men 18–50
Report overview
Copper (Copper Sebacate) · 1 mg OverallScore76
B Active Ingredient Quality & BioavailabilityA- Dose, Safety & Label TransparencyD+ Value
Copper sebacate is a well-absorbed organic form. 1 mg meets the daily allowance but remains below the collection median. The zinc-to-copper ratio of about 15.0:1 falls within the preferred balance range. Per-serving cost is around the collection’s moderate-value benchmark.
View ingredientView products
Vitamin B6 (Pyridoxine Hydrochloride) · 25 mg OverallScore70
F Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyB+ Value

Pyridoxine hydrochloride is the sole disclosed B6 form and no riboflavin conversion support is listed. The 25 mg serving sits within the preferred range and below the chronic neuropathy ceiling. Value is good when the comprehensive active profile is considered.

View ingredientView products
Vitamin B5 (Calcium D-Pantothenate) · 50 mg OverallScore66
B Active Ingredient Quality & BioavailabilityB Dose, Safety & Label TransparencyF Value

A clearly identified calcium pantothenate form offers stable, well-absorbed vitamin B5 for general metabolic support. The disclosed dose is adequate for maintenance but below stronger targeted levels. Missing excipient details and a high cost per active amount limit confidence in purity and value.

View ingredientView products
Loading alternative details
69 Performance

Adrenal Support

Vital Nutrients
<p>Eleuthero, ashwagandha, cordyceps, and pantothenic acid provide a more focused stress-and-fatigue strategy without yohimbe. It is not targeted to testosterone or libido, and bovine glandular ingredients plus adaptogen interactions require consideration.</p>
81 Performance

ThyroSense

Natural Factors WS WomenSense
<p>Well-chosen minerals and meaningful tyrosine provide a clearer foundation than the original’s wide, unevenly standardized blend. Thyroid-focused iodine, guggul, tyrosine, and ashwagandha need careful screening, and direct libido coverage is narrower.</p>
68 Performance

Adrenal Support

Vital Nutrients
<p>The eleuthero, ashwagandha, cordyceps, and pantothenic acid formula avoids the original’s undisclosed yohimbine exposure and high selenium total. Bovine glandular ingredients and medication interactions remain trade-offs, and testosterone alignment is limited.</p>
81 Budget

ThyroSense

Natural Factors WS WomenSense
<p>The much lower serving cost provides well-chosen minerals, substantial tyrosine, and ashwagandha with better practical value. It omits tribulus, maca, eleuthero, yohimbe, and most libido botanicals, while iodine and guggul require thyroid-related caution.</p>
80 Budget

Thyroid Health Formula

Natural Factors
<p>Tyrosine, minerals, and ashwagandha offer a simpler vitality formula at lower serving cost. It is thyroid-focused rather than libido-focused and requires caution with thyroid conditions or medication.</p>
80 Budget

ThyroSense

Natural Factors WS WomenSense
<p>The lower-cost blend supplies tyrosine, minerals, and ashwagandha with strong label value. Tribulus, maca, eleuthero, yohimbe, and the original’s broad male-vitality botanical system are absent.</p>
80 Value

Thyroid Health Formula

Natural Factors
<p>Practical serving value and well-chosen mineral forms make this a clearer vitality-focused option. It lacks tribulus, maca, epimedium, yohimbe, and most libido ingredients, while its thyroid actives require condition-specific caution.</p>
80 Value

ThyroSense

Natural Factors WS WomenSense
<p>The concise tyrosine, mineral, and ashwagandha strategy is easier to assess and more economical. The product serves a thyroid-support goal rather than the original’s broad male-response positioning.</p>
40 Value

Femesse

Arthur Andrew Medical
<p>Natural vitamin E and selenomethionine retain two nutrient elements at a somewhat lower serving cost. Two proprietary blends hide most actives, the formula targets a different population, and weak transparency makes it a poor direct alternative.</p>
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Carotenoids and carotenoids plus vitamin E protect against ultraviolet light-induced erythema in humans.
    Stahl W; Heinrich U; Jungmann H; Sies H; Tronnier H · The American journal of clinical nutrition · 2000
    Randomized trialSkin Health forVitamin E
  2. Selenium supplementation and secondary prevention of nonmelanoma skin cancer in a randomized trial.
    Duffield-Lillico AJ; Slate EH; Reid ME; Turnbull BW; Wilkins PA; Combs GF; Park HK; Gross EG; Graham GF; Stratton MS; Marshall JR; Clark LC; Nutritional Prevention of Cancer Study Group · Journal of the National Cancer Institute · 2003
    Randomized trial1,312 participantsSkin Health forSelenium
  3. Zinc, Copper, and Iron in Selected Skin Diseases.
    Podgórska A; Kicman A; Naliwajko S; Wacewicz-Muczyńska M; Niczyporuk M · International journal of molecular sciences · 2024
    Narrative reviewSkin Health forCopper
  4. Effect of ashwagandha (Withania somnifera) extract with Sominone (Somin-On™) to improve memory in adults with mild cognitive impairment: A randomized, double-blind, placebo-controlled study.
    Rai HP; Mishra DN · Journal of psychopharmacology (Oxford, England) · 2025
    Randomized trial40 participantsCognitive Support forAshwagandha
  5. Acute and Repeated Ashwagandha Supplementation Improves Markers of Cognitive Function and Mood.
    Leonard M; Dickerson B; Estes L; Gonzalez DE; Jenkins V; Johnson S; Xing D; Yoo C; Ko J; Purpura M; Jäger R; Faries M; Kephart W; Sowinski R; Rasmussen CJ; Kreider RB · Nutrients · 2024
    Randomized trial59 participantsCognitive Support forAshwagandha
  6. A standardized Ashwagandha root extract alleviates stress, anxiety, and improves quality of life in healthy adults by modulating stress hormones: Results from a randomized, double-blind, placebo-controlled study.
    Majeed M; Nagabhushanam K; Mundkur L · Medicine · 2023
    Randomized trial54 participantsCognitive Support forAshwagandha
  7. Efficacy and safety of ashwagandha root extract in children and adolescents with mild attention-deficit/hyperactivity disorder: a randomized, double-blind, placebo-controlled trial.
    Naik S; Muralidhar G; Rao BS; Agarwal S; Jain M · Journal of medicine and life · 2026
    Randomized trial58 participantsCognitive Support forAshwagandha
  8. Efficacy of Withania somnifera supplementation on adult's cognition and mood.
    Remenapp A; Coyle K; Orange T; Lynch T; Hooper D; Hooper S; Conway K; Hausenblas HA · Journal of Ayurveda and integrative medicine · 2022
    Randomized trial60 participantsCognitive Support forAshwagandha
  9. No benefit adding eleutherococcus senticosus to stress management training in stress-related fatigue/weakness, impaired work or concentration, a randomized controlled study.
    Schaffler K; Wolf OT; Burkart M · Pharmacopsychiatry · 2014
    Randomized trial144 participantsCognitive Support forEleuthero
  10. Efficacy of Ginkgo biloba extract EGb 761® in dementia with behavioural and psychological symptoms: A systematic review.
    von Gunten A; Schlaefke S; Überla K · The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry · 2017
    Meta-analysis1,628 participants4 studies pooledCognitive Support forGinkgo
  11. Efficacy of ginkgo diterpene lactone meglumine on cognitive function in patients with acute ischemic stroke: a predefined exploratory analysis of a multicenter, double-blind, randomized controlled trial.
    Tian X; Xu Q; Xia X; Zhang Y; Meng X; Wang A · Journal of neurology · 2024
    Randomized trial3,163 participantsCognitive Support forGinkgo
  12. A placebo-controlled, double-blind, randomized trial of an extract of Ginkgo biloba for dementia. North American EGb Study Group.
    Le Bars PL; Katz MM; Berman N; Itil TM; Freedman AM; Schatzberg AF · JAMA · 1997
    Randomized trial309 participantsCognitive Support forGinkgo
  13. Alleviating neuropsychiatric symptoms in dementia: the effects of Ginkgo biloba extract EGb 761. Findings from a randomized controlled trial.
    Bachinskaya N; Hoerr R; Ihl R · Neuropsychiatric disease and treatment · 2011
    Randomized trial410 participantsCognitive Support forGinkgo
  14. Efficacy and safety of a once-daily formulation of Ginkgo biloba extract EGb 761 in dementia with neuropsychiatric features: a randomized controlled trial.
    Ihl R; Bachinskaya N; Korczyn AD; Vakhapova V; Tribanek M; Hoerr R; Napryeyenko O; GOTADAY Study Group · International journal of geriatric psychiatry · 2013
    Randomized trial410 participantsCognitive Support forGinkgo
  15. A randomized, double blind, placebo controlled study to evaluate the effects of ashwagandha (Withania somnifera) extract on sleep quality in healthy adults.
    Deshpande A; Irani N; Balkrishnan R; Benny IR · Sleep medicine · 2021
    Randomized trial150 participantsGeneral Health forAshwagandha
  16. Effects of Ashwagandha ( Withania somnifera) standardized root extract on physical endurance and VO 2max in healthy adults performing resistance training: An eight-week, prospective, randomized, double-blind, placebo-controlled study.
    Verma N; Gupta SK; Patil S; Tiwari S; Mishra AK · F1000Research · 2024
    Randomized trial80 participantsGeneral Health forAshwagandha
  17. Efficacy of Ashwagandha (Withania somnifera [L.] Dunal) in improving cardiorespiratory endurance in healthy athletic adults.
    Choudhary B; Shetty A; Langade DG · Ayu · 2016
    Randomized trial50 participantsGeneral Health forAshwagandha
  18. Withania somnifera (L.) Dunal as Add-On Therapy for COPD Patients: A Randomized, Placebo-Controlled, Double-Blind Study.
    Singh P; Salman KA; Shameem M; Warsi MS · Frontiers in pharmacology · 2022
    Randomized trial150 participantsGeneral Health forAshwagandha
  19. Effect of Ashwagandha (Withania somnifera) extract on sleep: A systematic review and meta-analysis.
    Cheah KL; Norhayati MN; Husniati Yaacob L; Abdul Rahman R · PloS one · 2021
    Meta-analysis400 participants5 studies pooledGeneral Health forAshwagandha
  20. Associations of selenium status with all-cause and cause-specific mortality: a systematic review and meta-analysis of cohort studies.
    Cui Z; Xie R; Lu X; Schomburg L; Brenner H; Schöttker B · Redox biology · 2025
    Meta-analysis95 participants20 studies pooledGeneral Health forSelenium
  21. Dietary Antioxidants, Circulating Antioxidant Concentrations, Total Antioxidant Capacity, and Risk of All-Cause Mortality: A Systematic Review and Dose-Response Meta-Analysis of Prospective Observational Studies.
    Jayedi A; Rashidy-Pour A; Parohan M; Zargar MS; Shab-Bidar S · Advances in nutrition (Bethesda, Md.) · 2019
    Meta-analysis507,251 participants41 studies pooledGeneral Health forSelenium
  22. The efficacy and safety of selenium supplementation versus placebo in the treatment of Graves' orbitopathy: A systematic review and meta-analysis of randomised controlled trials.
    Sharabati I; Qafesha RM; Hindawi MD; Amro S; Ayesh BM · Clinical endocrinology · 2024
    Meta-analysis4 studies pooledGeneral Health forSelenium
  23. Associations of plasma metal concentrations with the risks of all-cause and cardiovascular disease mortality in Chinese adults.
    Shi L; Yuan Y; Xiao Y; Long P; Li W; Yu Y; Liu Y; Liu K; Wang H; Zhou L; Yang H; Li X; He M; Wu T · Environment international · 2021
    Cohort study6,155 participantsGeneral Health forSelenium
  24. Updates on clinical studies of selenium supplementation in radiotherapy.
    Puspitasari IM; Abdulah R; Yamazaki C; Kameo S; Nakano T; Koyama H · Radiation oncology (London, England) · 2015
    Systematic review16 studies pooledGeneral Health forSelenium
  25. Effectiveness of sodium bicarbonate and zinc chloride mouthwashes in the treatment of oral mucositis and quality of life in patients with cancer under chemotherapy.
    Mohammadi F; Oshvandi K; Kamallan SR; Khazaei S; Ranjbar H; Ahmadi-Motamayel F; Gillespie M; Jenabi E; Vafaei SY · Nursing open · 2022
    Randomized trial144 participantsGeneral Health forZinc
  26. Zinc supplementation in young children with acute diarrhea in India.
    Sazawal S; Black RE; Bhan MK; Bhandari N; Sinha A; Jalla S · The New England journal of medicine · 1995
    Randomized trial937 participantsGeneral Health forZinc
  27. Associations of mortality with ocular disorders and an intervention of high-dose antioxidants and zinc in the Age-Related Eye Disease Study: AREDS Report No. 13.
    Clemons TE; Kurinij N; Sperduto RD; AREDS Research Group · Archives of ophthalmology (Chicago, Ill. : 1960) · 2004
    Randomized trial4,753 participantsGeneral Health forZinc
  28. Effects of zinc and probiotic co-supplementation on inflammation, gastrointestinal symptoms, quality of life, and mood in irritable bowel syndrome patients.
    Rezazadegan M; Soheilipour M; Amani R · Scientific reports · 2026
    Randomized trial84 participantsGeneral Health forZinc
  29. Effect of zinc sulfate supplementation on premenstrual syndrome and health-related quality of life: Clinical randomized controlled trial.
    Siahbazi S; Behboudi-Gandevani S; Moghaddam-Banaem L; Montazeri A · The journal of obstetrics and gynaecology research · 2018
    Randomized trial142 participantsGeneral Health forZinc
  30. Effects of Withania somnifera root extract serum application on hair health in healthy adults: A prospective, double-blind, randomized, parallel, placebo-controlled study.
    Yerram C; Jillella A; Reddy V · Journal of Ayurveda and integrative medicine · 2023
    Randomized trial61 participantsHair Health forAshwagandha
  31. A Prospective, Randomized, Double-Blind, Placebo-Controlled Clinical Study of Efficacy and Safety of Ashwagandha Root Extract Capsule on Skin and Hair Health in Healthy Adults.
    Jillella A; Keerthi N; Venkateswar Reddy J · Phytotherapy research : PTR · 2026
    Randomized trialHair Health forAshwagandha
  32. Menkes disease and response to copper histidine: An Indian case series.
    Yoganathan S; Sudhakar SV; Arunachal G; Thomas M; Subramanian A; George R; Danda S · Annals of Indian Academy of Neurology · 2022
    Case series4 participantsHair Health forCopper
  33. Trace element levels in alopecia areata.
    Bhat YJ; Manzoor S; Khan AR; Qayoom S · Indian journal of dermatology, venereology and leprology · 2009
    Case-control study100 participantsHair Health forCopper
  34. UV damage to hair and the effect of antioxidants and metal chelators.
    Millington KR; Marsh JM · International journal of cosmetic science · 2021
    In vitro / ex vivo studyHair Health forCopper
  35. Preserving fibre health: reducing oxidative stress throughout the life of the hair fibre.
    Marsh JM; Davis MG; Lucas RL; Reilman R; Styczynski PB; Li C; Mamak M; McComb DW; Williams RE; Godfrey S; Navqi KR; Chechik V · International journal of cosmetic science · 2016
    In vitro / ex vivo studyHair Health forCopper
  36. The Safety and Efficacy of a Proprietary Bioactive Fatty Acids Extract From Saw Palmetto (Serenoa repens) for Promoting Hair Growth and Reducing Hair Loss in Adults With Self-Perceived Thinning Hair: 90-Day Results.
    Ablon G · Journal of cosmetic dermatology · 2025
    Randomized trial60 participantsHair Health forSaw Palmetto
  37. Effects of dietary supplements on androgenetic alopecia: a systematic review and network meta-analysis.
    Zhou L; Zhu W; Chen Y · Frontiers in nutrition · 2026
    Meta-analysis1,658 participants19 studies pooledHair Health forSaw Palmetto Hair Health forVitamin E
  38. The Safety and Efficacy of a Novel Saw Palmetto (Serenoa repens) Extract for Promoting Hair Growth in Adults With Self-Perceived Thinning Hair: 180-Day Results.
    Ablon G · Journal of cosmetic dermatology · 2026
    Randomized trial60 participantsHair Health forSaw Palmetto
  39. Beyond Minoxidil: Off-Label Therapies for Male Androgenetic Alopecia-A Systematic Review with Network Meta-Analyses.
    Gupta AK; Compton SAH; Liddy A; Talukder M; Wang T; Bamimore MA · Medicina (Kaunas, Lithuania) · 2026
    Meta-analysis50 participants23 studies pooledHair Health forSaw Palmetto
  40. Comparitive effectiveness of finasteride vs Serenoa repens in male androgenetic alopecia: a two-year study.
    Rossi A; Mari E; Scarno M; Garelli V; Maxia C; Scali E; Iorio A; Carlesimo M · International journal of immunopathology and pharmacology · 2013
    Non-randomized trial100 participantsHair Health forSaw Palmetto
  41. Beyond Efficacy: 0.6% Selenium Disulfide Shampoo Matches 2% Ketoconazole for Seborrheic Dermatitis with Superior Cosmesis.
    Farris PK; Barbosa V; Houshman EB; Kovylkina N · Journal of drugs in dermatology : JDD · 2026
    Randomized trial87 participantsHair Health forSelenium
  42. Selenium Disulfide-based shampoo applied for 4 weeks significantly improves dandruff and seborrheic dermatitis.
    Turcu G; Artenie C; Nowicka D; Arenbergerová M; Lazaridou E; Khobzei K; Ataseven A; Part M; Leclerc-Mercier S · European journal of dermatology : EJD · 2023
    Observational study1,407 participantsHair Health forSelenium
  43. A Comparative Randomized Clinical Study Assessing the Efficacy of a 1% Selenium Disulfide-Based Shampoo versus 2% Ketoconazole Shampoo in Subjects with Moderate to Severe Scalp Seborrheic Dermatitis.
    Barbosa V; Melo DF; Vañó-Galván S; Lutchmanen-Kolanthan V; Sant'Anna B; Leclerc-Mercier S; Reygagne P · Skin appendage disorders · 2025
    Randomized trial64 participantsHair Health forSelenium
  44. Changes of serum trace elements level in patients with alopecia areata: A meta-analysis.
    Jin W; Zheng H; Shan B; Wu Y · The Journal of dermatology · 2018
    Meta-analysis764 participantsHair Health forSelenium
  45. Scientific opinion on the tolerable upper intake level for selenium.
    EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA); Turck D; Bohn T; Castenmiller J; de Henauw S; Hirsch-Ernst KI; Knutsen HK; Maciuk A; Mangelsdorf I; McArdle HJ; Peláez C; Pentieva K; Siani A; Thies F; Tsabouri S; Vinceti M; Aggett P; Crous Bou M; Cubadda F; Ciccolallo L; de Sesmaisons Lecarré A; Fabiani L; Titz A; Naska A · EFSA journal. European Food Safety Authority · 2023
    Systematic reviewHair Health forSelenium
  46. Effects of tocotrienol supplementation on hair growth in human volunteers.
    Beoy LA; Woei WJ; Hay YK · Tropical life sciences research · 2014
    Randomized trial38 participantsHair Health forVitamin E
  47. Evaluation of the Safety and Effectiveness of Nutritional Supplements for Treating Hair Loss: A Systematic Review.
    Drake L; Reyes-Hadsall S; Martinez J; Heinrich C; Huang K; Mostaghimi A · JAMA dermatology · 2023
    Systematic review30 studies pooledHair Health forVitamin E
  48. The effects of minoxidil, 1% pyrithione zinc and a combination of both on hair density: a randomized controlled trial.
    Berger RS; Fu JL; Smiles KA; Turner CB; Schnell BM; Werchowski KM; Lammers KM · The British journal of dermatology · 2003
    Randomized trial200 participantsHair Health forZinc
  49. Incubatory environment of the scalp impacts pre-emergent hair to affect post-emergent hair cuticle integrity.
    Schwartz JR; Henry JP; Kerr KM; Flagler MJ; Page SH; Redman-Furey N · Journal of cosmetic dermatology · 2018
    Randomized trialHair Health forZinc
  50. A comparison of hair quality and cosmetic acceptance following the use of two anti-dandruff shampoos.
    Draelos ZD; Kenneally DC; Hodges LT; Billhimer W; Copas M; Margraf C · The journal of investigative dermatology. Symposium proceedings · 2006
    Randomized trial40 participantsHair Health forZinc
  51. BMI and levels of zinc, copper in hair, serum and urine of Turkish male patients with androgenetic alopecia.
    Ozturk P; Kurutas E; Ataseven A; Dokur N; Gumusalan Y; Gorur A; Tamer L; Inaloz S · Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) · 2015
    Case-control study216 participantsHair Health forZinc
  52. Analysis of serum zinc and copper concentrations in hair loss.
    Kil MS; Kim CW; Kim SS · Annals of dermatology · 2013
    Case-control study342 participantsHair Health forZinc
  53. Flow-cytometric studies with eleutherococcus senticosus extract as an immunomodulatory agent.
    Bohn B; Nebe CT; Birr C · Arzneimittel-Forschung · 1988
    Randomized trial36 participantsImmunity forEleuthero
  54. Effects of selenium supplementation on selenoprotein gene expression and response to influenza vaccine challenge: a randomised controlled trial.
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    Janbakhsh A; Mansouri F; Vaziri S; Sayad B; Afsharian M; Rahimi M; Shahebrahimi K; Salari F · Caspian journal of internal medicine · 2013
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    Gärtner R; Gasnier BC; Dietrich JW; Krebs B; Angstwurm MW · The Journal of clinical endocrinology and metabolism · 2002
    Randomized trial70 participantsImmunity forSelenium
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    Vlieg-Boerstra B; de Jong N; Meyer R; Agostoni C; De Cosmi V; Grimshaw K; Milani GP; Muraro A; Oude Elberink H; Pali-Schöll I; Roduit C; Sasaki M; Skypala I; Sokolowska M; van Splunter M; Untersmayr E; Venter C; O'Mahony L; Nwaru BI · Allergy · 2022
    Meta-analysis199,055 participants115 studies pooledImmunity forZinc
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    Sazawal S; Black RE; Jalla S; Mazumdar S; Sinha A; Bhan MK · Pediatrics · 1998
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    Rerksuppaphol S; Rerksuppaphol L · Pediatric reports · 2020
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    Fortes C; Forastiere F; Agabiti N; Fano V; Pacifici R; Virgili F; Piras G; Guidi L; Bartoloni C; Tricerri A; Zuccaro P; Ebrahim S; Perucci CA · Journal of the American Geriatrics Society · 1998
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    Vecchietti A; Strano P; Minutolo G; Grieco V; Cappuccio G; Granvillano G; Confalonieri L; Briganti GL; Raso E; Chimienti M; Pellegrini M; Mercogliano M; Spatari G; Lugli C; Urbano T; Lorenzon A · Journal of preventive medicine and hygiene · 2026
    Systematic review13 studies pooledImmunity forZinc
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    Zhu X; Zeng Q; Lei Y; Xu D · Frontiers in pharmacology · 2026
    Meta-analysis1,249 participants20 studies pooledTestosterone Support forAshwagandha
  65. Effect of standardized root extract of ashwagandha (Withania somnifera) on well-being and sexual performance in adult males: A randomized controlled trial.
    Chauhan S; Srivastava MK; Pathak AK · Health science reports · 2024
    Randomized trial50 participantsTestosterone Support forAshwagandha
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    Smith SJ; Lopresti AL; Teo SYM; Fairchild TJ · Advances in nutrition (Bethesda, Md.) · 2021
    Systematic review32 studies pooledTestosterone Support forAshwagandha
  67. Do "testosterone boosters" really increase serum total testosterone? A systematic review.
    Morgado A; Tsampoukas G; Sokolakis I; Schoentgen N; Urkmez A; Sarikaya S · International journal of impotence research · 2024
    Systematic review3 studies pooledTestosterone Support forAshwagandha
  68. Safety and Tolerability of Withania somnifera Root Extract in Healthy Male Participants: A Pilot Randomized, Double-Blind, Placebo-Controlled Clinical Trial.
    Vaidya N; Agarwal R; Kshirsagar P; Ganu G; Nagore D; Mehta A; Vora A; Nair S · Food science & nutrition · 2025
    Randomized trial40 participantsTestosterone Support forAshwagandha
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    Safarinejad MR; Safarinejad S · The Journal of urology · 2009
    Randomized trial468 participantsTestosterone Support forSelenium
  70. The association between metal exposure and semen quality in Chinese males: The mediating effect of androgens.
    Liu P; Yuan G; Zhou Q; Liu Y; He X; Zhang H; Guo Y; Wen Y; Huang S; Ke Y; Chen J · Environmental pollution (Barking, Essex : 1987) · 2020
    Cross-sectional study1,136 participantsTestosterone Support forSelenium
  71. In utero and peripubertal metals exposure in relation to reproductive hormones and sexual maturation and progression among girls in Mexico City.
    Ashrap P; Sánchez BN; Téllez-Rojo MM; Basu N; Tamayo-Ortiz M; Peterson KE; Meeker JD; Watkins DJ · Environmental research · 2019
    Observational study132 participantsTestosterone Support forSelenium
  72. Relationship between serum levels of testosterone, zinc and selenium in infertile males attending fertility clinic in Nnewi, south east Nigeria.
    Oluboyo AO; Adijeh RU; Onyenekwe CC; Oluboyo BO; Mbaeri TC; Odiegwu CN; Chukwuma GO; Onwuasoanya UF · African journal of medicine and medical sciences · 2013
    Observational studyTestosterone Support forSelenium
  73. EVALUATION OF MALE SEX HORMONES AND TRACE ELEMENTS IN MALE TYPE 2 DIABETIC PATIENTS ATTENDING NNAMDI AZIKIWE UNIVERSITY TEACHING HOSPITAL DIABETIC CLINICS.
    Ubajaka CF; Meludu SC; Dioka CE; Onah CE; Osuji CU; Modebe IA; Ifeadike GC; Okwara JE; Amah UK; Nnebue CC · Nigerian journal of medicine : journal of the National Association of Resident Doctors of Nigeria · 2015
    Cross-sectional studyTestosterone Support forSelenium
  74. Efficacy of Tribulus Terrestris for the treatment of premenopausal women with hypoactive sexual desire disorder: a randomized double-blinded, placebo-controlled trial.
    Vale FBC; Zanolla Dias de Souza K; Rezende CR; Geber S · Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology · 2018
    Randomized trial40 participantsTestosterone Support forTribulus
  75. The Effects of 6 Weeks of Tribulus terrestris L. Supplementation on Body Composition, Hormonal Response, Perceived Exertion, and CrossFit® Performance: A Randomized, Single-Blind, Placebo-Controlled Study.
    Fernández-Lázaro D; Mielgo-Ayuso J; Del Valle Soto M; Adams DP; González-Bernal JJ; Seco-Calvo J · Nutrients · 2021
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  76. Tribulus terrestris versus placebo in the treatment of erectile dysfunction and lower urinary tract symptoms in patients with late-onset hypogonadism: A placebo-controlled study.
    GamalEl Din SF; Abdel Salam MA; Mohamed MS; Ahmed AR; Motawaa AT; Saadeldin OA; Elnabarway RR · Urologia · 2019
    Randomized trial70 participantsTestosterone Support forTribulus
  77. Efficacy of Tribulus terrestris for the treatment of hypoactive sexual desire disorder in postmenopausal women: a randomized, double-blinded, placebo-controlled trial.
    de Souza KZ; Vale FB; Geber S · Menopause (New York, N.Y.) · 2018
    Randomized trial45 participantsTestosterone Support forTribulus
  78. Effect of oral administration of Tribulus terrestris extract on semen quality and body fat index of infertile men.
    Salgado RM; Marques-Silva MH; Gonçalves E; Mathias AC; Aguiar JG; Wolff P · Andrologia · 2018
    Single-arm trial65 participantsTestosterone Support forTribulus
  79. Environmental exposure to metals and male reproductive hormones: circulating testosterone is inversely associated with blood molybdenum.
    Meeker JD; Rossano MG; Protas B; Padmanahban V; Diamond MP; Puscheck E; Daly D; Paneth N; Wirth JJ · Fertility and sterility · 2010
    Cross-sectional study219 participantsTestosterone Support forZinc
  80. Nonpharmacological Interventions for the Management of Testosterone and Sperm Parameters: A Scoping Review.
    Santos HO; Cadegiani FA; Forbes SC · Clinical therapeutics · 2022
    Scoping reviewTestosterone Support forZinc
  81. Zinc is an Essential Element for Male Fertility: A Review of Zn Roles in Men's Health, Germination, Sperm Quality, and Fertilization.
    Fallah A; Mohammad-Hasani A; Colagar AH · Journal of reproduction & infertility · 2020
    Narrative reviewTestosterone Support forZinc
  82. Clinical, endocrinological and biochemical effects of zinc deficiency.
    Prasad AS · Clinics in endocrinology and metabolism · 1986
    Narrative reviewTestosterone Support forZinc
  83. Clinical, endocrinologic, and biochemical effects of zinc deficiency.
    Prasad AS · Special topics in endocrinology and metabolism · 1986
    Narrative reviewTestosterone Support forZinc