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50 & Wiser Men

Garden of Life Vitamin Code
4.7
★ ★ ★ ★ ★
(3370 ratings)
Selenium 55 mcg
Boron 1 mg
Molybdenum 45 mcg
Manganese 2.3 mg
Vitamin K 120 mcg
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Score65

A broad older-men's multivitamin with useful vitamin forms and chelated trace minerals. Opaque blends, four capsules, and token specialty ingredients reduce its appeal.

How scoring works
Quantity:120 Capsule(s) • (30 servings)
Goals:
General Health
Immunity

Score 65

A broad older-men's multivitamin with useful vitamin forms and chelated trace minerals. Opaque blends, four capsules, and token specialty ingredients reduce its appeal.

How scoring works

Also available as

1 option
240 servings 2 Capsule(s) • 240 Capsule(s) • 60 servings $60.89 ($1.01 per serving)
$32.19($1.07 per serving)
Vitacost
$ 37.89
Amazon
$ 68.72
Pure Formulas
$ 34.29
iHerb
$ 34.29
Walmart
$ 32.19
Report prices

Analysis

The four-capsule serving supplies vitamin D3, natural vitamin E, vitamin K1, methylcobalamin, zinc, selenium, manganese, molybdenum, and other core vitamins. Beta-carotene supplies vitamin A without preformed retinol.

A 546 mg fruit and vegetable blend and smaller probiotic, enzyme, and antioxidant blends lack individual doses. CoQ10 at 425 mcg and lycopene at 250 mcg are token amounts rather than meaningful cardiovascular actives.

The formula fits older men wanting broad multivitamin maintenance and who accept a high capsule count. No calcium or magnesium is included, and the small MK-4 amount does not create complete bone support.

Who is it for
  • Men over 50 seeking broad micronutrient coverage
  • Users who prefer food- and yeast-based nutrients
  • People comfortable taking four capsules
Best for
  • General multivitamin maintenance
  • Vitamin D and zinc intake
  • Iron-free micronutrient coverage

Pros

  • Uses vitamin D3 and methylcobalamin
  • Natural vitamin E
  • Includes chelated zinc and manganese
  • Broad vitamin profile
  • Iron-free design

Cons

  • Four-capsule serving
  • Several blends lack individual amounts
  • CoQ10 and lycopene are token doses
  • No calcium or magnesium
  • Only 20 mcg MK-4

Warnings

  • Vitamin K can alter warfarin and other vitamin K antagonist management
  • Probiotic and enzyme blends may not suit every digestive tolerance
  • Kelp-derived iodine may matter for people with thyroid conditions
  • Opaque blends make allergy screening more difficult

Nutrient quality

75 High impact

The formula covers many daily nutrients but has a material dose or coverage weakness. Useful forms remain present, while small extras and vague blends do not correct the gap.

Ingredient transparency

63 Moderate impact

Main vitamin and mineral amounts are shown, but one or more blends hide their components. Complete inactive ingredients and full use directions are also not supplied.

Customer satisfaction

71 High impact

The aggregate satisfaction signal is strong and the supplied volume is substantial. No specific experience details are supplied to assess repeated complaints or purpose-related outcomes.

Value for money

53 Moderate impact

Broad coverage partly supports the market position, but the serving value is weak. Opaque blends and token specialty ingredients reduce competitiveness.

Report analysis

Goals

General Health
General Health
Impact
High effect
A- Goal FitB Strength of SupportB CoverageB- Formula Quality
Folate · 400 mcg DFEVitamin B12 · 40.01 mcgVitamin D · 50 mcgVitamin K · 20 mcgBoron · 1 mgSelenium · 55 mcgZinc · 11 mgVitamin C · 90 mg

The age-focused multivitamin covers many essential vitamins and trace minerals, including vitamin D3, methylcobalamin, zinc, and selenium. The moderate nutrient amounts are generally more suitable for daily maintenance than megadose use.

Vitamin K2 is present as short-acting MK-4 at a small amount, and the exact chemistry of several yeast-bound minerals is unclear. The fruit, enzyme, and antioxidant blends are too small and opaque to add much confidence.

Study evidence
Boron Supportive 6 studies
Selenium Supportive 70 studies
Vitamin K Supportive 34 studies
Zinc Supportive 60 studies
Immunity
Immunity
Impact
High effect
A- Goal FitB- Strength of SupportB+ CoverageC+ Formula Quality
Vitamin C · 90 mgZinc · 11 mgVitamin A · 1080 mcgVitamin D · 50 mcgSelenium · 55 mcg

Vitamin A, vitamin C, vitamin D3, zinc, and selenium cover several complementary immune functions. Vitamin D3 is substantial, and selenium yeast offers favorable absorption potential.

Vitamin C and selenium fall below stronger immune-focused amounts, while small proprietary complexes cannot be evaluated ingredient by ingredient. Vitamin K can interfere with warfarin, so users of that medicine need clinician-guided dosing.

Study evidence
Selenium Mixed 37 studies
Vitamin A Supportive 107 studies
Vitamin C Supportive 53 studies
Vitamin D Supportive 85 studies
Zinc Supportive 73 studies
Bone Health
Bone Health
Impact
Moderate effect
B- Goal FitD Strength of SupportD+ CoverageC- Formula Quality
Vitamin K · 20 mcgVitamin D · 50 mcgManganese · 2.3 mgBoron · 1 mgZinc · 11 mgVitamin C · 90 mg

Vitamin D3, vitamin K1, a small amount of K2 as MK-4, zinc, manganese, and boron provide partial skeletal support. The vitamins address mineral signaling even though the product is not a dedicated bone supplement.

Calcium and magnesium are absent, boron is low, and MK-4 is modest compared with a focused K2 serving. The formula cannot supply the structural minerals needed for comprehensive bone support.

Study evidence
Boron Supportive 5 studies
Manganese Adverse 12 studies
Vitamin D Supportive 202 studies
Vitamin K Supportive 78 studies
Zinc Supportive 33 studies
Cardiovascular Support
Cardiovascular Support
Impact
Moderate effect
C Goal FitD+ Strength of SupportD+ CoverageC- Formula Quality
Vitamin K · 20 mcgVitamin D · 50 mcgCoenzyme Q-10 · 425 mcgSelenium · 55 mcgVitamin B12 · 40.01 mcgVitamin B6 · 3.4 mgVitamin E · 15 mgLycopene · 250 mcgFolate · 400 mcg DFENiacin · 16 mgVitamin C · 90 mg

Vitamin D3, low-dose vitamin K2, B vitamins, and trace CoQ10 provide several heart-related nutrient signals. The general vitamins are adequate, while K2 and CoQ10 make only token cardiovascular contributions.

No omega fatty acids, meaningful CoQ10, magnesium support, or vasodilator anchors the formula. The broad raw-food multivitamin contains many ingredients without direct cardiovascular value.

Study evidence
Vitamin K Supportive 40 studies
Anti-Aging
Anti-Aging
Impact
Moderate effect
D+ Goal FitD+ Strength of SupportC- CoverageD+ Formula Quality
Coenzyme Q-10 · 425 mcgFolate · 400 mcg DFEVitamin B12 · 40.01 mcgVitamin K · 20 mcgVitamin D · 50 mcg

Vitamins, minerals, and antioxidant nutrients provide broad nutritional support relevant to healthy aging. The formula includes CoQ10, but only at a token microgram amount.

No mitochondrial, NAD-related, glycation, collagen, or omega-3 active reaches a meaningful anti-aging dose. The broad wellness blends make the label look comprehensive while individual secondary ingredients remain difficult to assess.

Ingredients

IngredientAmount per serving
Vitamin A (Beta-Carotene)
 1080 mcg
Vitamin C (S. cerevisiae)
 90 mg
Vitamin D (D3)
 50 mcg
Vitamin E (D-Alpha-Tocopherol)
 15 mg
Vitamin K (K1)
 120 mcg
Thiamin (S. cerevisiae)
 6.36 mg
Riboflavin (S. cerevisiae)
 3.12 mg
Niacin (Niacinamide)
 16 mg
Vitamin B6 (S. cerevisiae)
 3.4 mg
Folate (S. cerevisiae)
 400 mcg DFE
Vitamin B12 (Methylcobalamin)
 40.01 mcg
Biotin (Saccharomyces cerevisiae)
 30 mcg
Pantothenic Acid (S. cerevisiae)
 10 mg
Iodine (organic Sea Kelp)
 75 mcg
Zinc (Brown Rice Chelate)
 11 mg
Selenium (S. cerevisiae)
 55 mcg
Manganese (Brown Rice Chelate)
 2.3 mg
Chromium (S. cerevisiae)
 35 mcg
Molybdenum (Brown Rice Chelate)
 45 mcg
Vitamin K2 (Menaquinone-4)
 20 mcg
CoQ10
425 mcg
Lycopene
250 mcg
Boron (S. cerevisiae)
 1 mg
Vanadium (S. cerevisiae)
 10 mcg
Raw Organic Fruit & Vegetable Blend
546 mg
Raw Probiotic & Enzyme Blend
40 mg
Raw Antioxidant & Immune Support Complex
20 mg
Men 50+ Gluten Free Kosher Dairy Free
Report overview
Selenium (S. cerevisiae) · 55 mcg OverallScore65
B+ Active Ingredient Quality & BioavailabilityB Dose, Safety & Label TransparencyF Value

selenium yeast offers strong absorption potential. The 55 mcg serving stays safely below the upper limit but falls short of the stated maintenance target. Selenium-specific value is weak after standardizing to the target amount, although other ingredients may contribute separate value.

View ingredientView products
Boron (S. cerevisiae) · 1 mg OverallScore45
D- Active Ingredient Quality & BioavailabilityC+ Dose, Safety & Label TransparencyF Value

A yeast-bound source does not confirm a validated organic chelate or nature-identical boron form. The elemental amount is clearly disclosed but remains below the stated maintenance level. Very high normalized cost makes it weak value for boron-focused use.

View ingredientView products
Molybdenum (Brown Rice Chelate) · 45 mcg OverallScore44
F Active Ingredient Quality & BioavailabilityC Dose, Safety & Label TransparencyF Value

Brown rice chelate names a source but does not identify the specific ligand binding the molybdenum. The 45 mcg serving falls below the collection minimum, though it remains well within the adult safety limit. Serving cost is high, and the below-target molybdenum amount makes the value weak.

View ingredientView products
Loading alternative details
88 Performance

Men Over 55 One Daily

MegaFood
<p>Stronger ingredient quality and focus come from a simpler design: broad vitamins and several useful nutrient forms provide practical one-daily maintenance for older men. Yeast-bound trace minerals are less specific than named chelates, and the phenolic blend adds uncertain value.</p>
88 Performance

Raw One For Men

Garden of Life Vitamin Code
<p>Stronger ingredient quality and focus come from a simpler design: a compact one-capsule formula with vitamin D3, selenium, manganese, molybdenum, and broad vitamins supports men’s maintenance needs. Small botanical and enzyme blends remain vague, though they do not overwhelm the nutrient base.</p>
78 Performance

50 & Wiser Women

Garden of Life Vitamin Code
<p>Stronger ingredient quality and focus come from a simpler design: broad vitamins, vitamin D3, selenium, manganese, and molybdenum support maintenance needs for older women. A four-capsule serving and opaque specialty blends still limit convenience and transparency. The formula targets women, so its iron and other sex-specific amounts should be checked against individual needs.</p>
91 Budget

Men Over 55 One Daily

MegaFood
<p>Better serving value comes with a simpler profile: a one-daily formula uses useful nutrient forms and balanced maintenance amounts for older men. The small phenolic blend and incomplete inactive-ingredient details leave some uncertainty.</p>
87 Budget

Raw One For Men

Garden of Life Vitamin Code
<p>Better serving value comes with a simpler profile: a one-capsule formula with vitamin D3, selenium, manganese, molybdenum, and broad vitamins provides focused coverage for men. A zero-value enzyme entry and vague small blends create avoidable label uncertainty.</p>
91 Budget

Women Over 55 One Daily

MegaFood
<p>Better serving value comes with a simpler profile: a one-daily formula with useful vitamin forms, manganese, and molybdenum provides efficient coverage for older women. Vitamin K is limited to K1, several major minerals are absent, and the phenolic blend is not fully detailed. The formula targets women, so its iron and other sex-specific amounts should be checked against individual needs.</p>
90 Value

Men Over 55 One Daily

MegaFood
<p>A better balance of nutrient quality, convenience, and cost comes from a simpler design: a one-daily formula combines useful nutrient forms with balanced maintenance amounts for older men. The small phenolic blend and incomplete inactive-ingredient details temper transparency.</p>
90 Value

Women Over 55 One Daily

MegaFood
<p>A better balance of nutrient quality, convenience, and cost comes from a simpler design: a one-daily formula with thoughtful vitamin forms, manganese, and molybdenum provides focused coverage for older women. Vitamin K is limited to K1, several major minerals are absent, and the small phenolic blend is opaque. The formula targets women, so its iron and other sex-specific amounts should be checked against individual needs.</p>
78 Value

Men

Garden of Life Vitamin Code
<p>A better balance of nutrient quality, convenience, and cost comes from a simpler design: vitamin D3, zinc, selenium, methylcobalamin, and broad vitamins provide practical daily coverage for men. The four-capsule serving and several opaque blends weaken convenience and transparency.</p>
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Three-year low-dose menaquinone-7 supplementation helps decrease bone loss in healthy postmenopausal women.
    Knapen MH; Drummen NE; Smit E; Vermeer C; Theuwissen E · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2014
    Randomized trial244 participantsBone Health forVitamin K
  2. Investigating the interrelationship of vitamin K and vitamin D status on bone density: results from the VITamin D and OmegA-3 TriaL.
    Chou SH; Booth SL; Cook NR; Kim E; Kotler G; Fu X; Buring JE; Manson JE; LeBoff MS · JBMR plus · 2026
    Randomized trial771 participantsBone Health forVitamin K
  3. Efficacy and safety of vitamin K2 for postmenopausal women with osteoporosis at a long-term follow-up: meta-analysis and systematic review.
    Zhou M; Han S; Zhang W; Wu D · Journal of bone and mineral metabolism · 2022
    Meta-analysis6,853 participants9 studies pooledBone Health forVitamin K
  4. [Comparative study of the urinary excretion of boron, calcium, magnesium and phosphorus in postmenopausal women with and without osteoporosis].
    José Ramón V; Mora Mora M; Marino Alarcón O; Hernández G; Josefina Linares L; Urdaneta Romero H; Arévalo González E · Investigacion clinica · 2013
    Case-control study45 participantsBone Health forBoron
  5. Effect of dietary boron on mineral, estrogen, and testosterone metabolism in postmenopausal women.
    Nielsen FH; Hunt CD; Mullen LM; Hunt JR · FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 1987
    Single-arm trial12 participantsBone Health forBoron
  6. The relationship between boron and magnesium status and bone mineral density in the human: a review.
    Volpe SL; Taper LJ; Meacham S · Magnesium research · 1994
    Narrative reviewBone Health forBoron
  7. Effects of boron supplementation on bone mineral density and dietary, blood, and urinary calcium, phosphorus, magnesium, and boron in female athletes.
    Meacham SL; Taper LJ; Volpe SL · Environmental health perspectives · 1995
    Randomized trial28 participantsBone Health forBoron
  8. Metabolic responses of postmenopausal women to supplemental dietary boron and aluminum during usual and low magnesium intake: boron, calcium, and magnesium absorption and retention and blood mineral concentrations
    C D Hunt, J L Herbel, F H Nielsen · The American Journal of Clinical Nutrition · 1997
    Non-randomized trial11 participantsBone Health forBoron
  9. Risk of Environmental Chemicals on Bone Fractures Is Independent of Low Bone Mass in US Adults: Insights from 2017 to 2018 NHANES.
    Ling R; Ai Y; Chen C; Zhang J; Zou Z; Cheng S; Li C; Li X; Wang B · Metabolites · 2023
    Cross-sectional study2,640 participantsBone Health forManganese
  10. The Manganese-Bone Connection: Investigating the Role of Manganese in Bone Health.
    Taskozhina G; Batyrova G; Umarova G; Issanguzhina Z; Kereyeva N · Journal of clinical medicine · 2024
    Narrative reviewBone Health forManganese
  11. Associations of multiple metals with bone mineral density: A population-based study in US adults.
    Wei MH; Cui Y; Zhou HL; Song WJ; Di DS; Zhang RY; Huang Q; Liu JA; Wang Q · Chemosphere · 2021
    Cross-sectional studyBone Health forManganese
  12. Sex-specific associations of urinary mixed-metal concentrations with femoral bone mineral density among older people: an NHANES (2017-2020) analysis.
    Li H; Li G; Yi M; Zhou J; Deng Y; Huang Y; He S; Meng X; Liu L · Frontiers in public health · 2024
    Cross-sectional study31 participantsBone Health forManganese
  13. Relationship between blood manganese and bone mineral density and bone mineral content in adults: A population-based cross-sectional study.
    Wang C; Zhu Y; Long H; Ou M; Zhao S · PloS one · 2022
    Cross-sectional study9,732 participantsBone Health forManganese
  14. Pregnancy vitamin D supplementation and offspring bone mineral density in childhood follow-up of a randomized controlled trial.
    Moon RJ; D' Angelo S; Curtis EM; Ward KA; Crozier SR; Schoenmakers I; Javaid MK; Bishop NJ; Godfrey KM; Cooper C; Harvey NC; MAVIDOS Trial Group · The American journal of clinical nutrition · 2024
    Randomized trial454 participantsBone Health forVitamin D
  15. Vitamin D analogs and bone: preclinical and clinical studies with eldecalcitol.
    Matsumoto T; Takano T; Saito H; Takahashi F · BoneKEy reports · 2014
    Narrative reviewBone Health forVitamin D
  16. Efficacy of vitamin D fortified foods on bone mineral density and serum bone biomarkers: A systematic review and meta-analysis of interventional studies.
    Tangestani H; Djafarian K; Emamat H; Arabzadegan N; Shab-Bidar S · Critical reviews in food science and nutrition · 2020
    Meta-analysis1,786 participants20 studies pooledBone Health forVitamin D
  17. Cholecalciferol Supplementation Attenuates Bone Loss in Incident Kidney Transplant Recipients: A Prespecified Secondary Endpoint Analysis of a Randomized Controlled Trial.
    Tsujita M; Doi Y; Obi Y; Hamano T; Tomosugi T; Futamura K; Okada M; Hiramitsu T; Goto N; Isaka Y; Takeda A; Narumi S; Watarai Y · Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2022
    Randomized trial193 participantsBone Health forVitamin D
  18. Vitamin D supplementation and bone health in post-menopausal women: a 24-month randomized controlled intervention with enhanced bioavailability formulations.
    Rasool N; Munir Y · European journal of clinical nutrition · 2026
    Randomized trial612 participantsBone Health forVitamin D
  19. Vitamin K and the prevention of fractures: systematic review and meta-analysis of randomized controlled trials.
    Cockayne S; Adamson J; Lanham-New S; Shearer MJ; Gilbody S; Torgerson DJ · Archives of internal medicine · 2006
    Meta-analysis13 studies pooledBone Health forVitamin K
  20. Effect of combined administration of vitamin D3 and vitamin K2 on bone mineral density of the lumbar spine in postmenopausal women with osteoporosis.
    Iwamoto J; Takeda T; Ichimura S · Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association · 2001
    Randomized trial92 participantsBone Health forVitamin K
  21. Low-dose vitamin K2 (MK-4) supplementation for 12 months improves bone metabolism and prevents forearm bone loss in postmenopausal Japanese women.
    Koitaya N; Sekiguchi M; Tousen Y; Nishide Y; Morita A; Yamauchi J; Gando Y; Miyachi M; Aoki M; Komatsu M; Watanabe F; Morishita K; Ishimi Y · Journal of bone and mineral metabolism · 2015
    Randomized trial48 participantsBone Health forVitamin K
  22. Increased incidence of fractures in middle-aged and elderly men with low intakes of phosphorus and zinc.
    Elmståhl S; Gullberg B; Janzon L; Johnell O; Elmståhl B · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 1999
    Cohort study6,576 participantsBone Health forZinc
  23. Zinc Supplementation Increases Procollagen Type 1 Amino-Terminal Propeptide in Premenarcheal Girls: A Randomized Controlled Trial.
    Berger PK; Pollock NK; Laing EM; Chertin V; Bernard PJ; Grider A; Shapses SA; Ding KH; Isales CM; Lewis RD · The Journal of nutrition · 2016
    Randomized trial147 participantsBone Health forZinc
  24. Randomized controlled trial of prenatal zinc supplementation and fetal bone growth.
    Merialdi M; Caulfield LE; Zavaleta N; Figueroa A; Costigan KA; Dominici F; Dipietro JA · The American journal of clinical nutrition · 2004
    Randomized trial242 participantsBone Health forZinc
  25. The effects of zinc supplementation on serum zinc, alkaline phosphatase activity and fracture healing of bones.
    Sadighi A; Roshan MM; Moradi A; Ostadrahimi A · Saudi medical journal · 2009
    Randomized trial60 participantsBone Health forZinc
  26. Is Zinc an Important Trace Element on Bone-Related Diseases and Complications? A Meta-analysis and Systematic Review from Serum Level, Dietary Intake, and Supplementation Aspects.
    Ceylan MN; Akdas S; Yazihan N · Biological trace element research · 2021
    Meta-analysis40 studies pooledBone Health forZinc
  27. Vitamin K Intake and Atherosclerotic Cardiovascular Disease in the Danish Diet Cancer and Health Study.
    Bellinge JW; Dalgaard F; Murray K; Connolly E; Blekkenhorst LC; Bondonno CP; Lewis JR; Sim M; Croft KD; Gislason G; Torp-Pedersen C; Tjønneland A; Overvad K; Hodgson JM; Schultz C; Bondonno NP · Journal of the American Heart Association · 2021
    Cohort study53,372 participantsCardiovascular Support forVitamin K
  28. Menaquinone-7 supplementation improves arterial stiffness in healthy postmenopausal women. A double-blind randomised clinical trial.
    Knapen MH; Braam LA; Drummen NE; Bekers O; Hoeks AP; Vermeer C · Thrombosis and haemostasis · 2016
    Randomized trial244 participantsCardiovascular Support forVitamin K
  29. Effects of One-Year Menaquinone-7 Supplementation on Vascular Stiffness and Blood Pressure in Post-Menopausal Women.
    de Vries F; Bittner R; Maresz K; Machuron F; Gåserød O; Jeanne JF; Schurgers LJ · Nutrients · 2025
    Randomized trial165 participantsCardiovascular Support forVitamin K
  30. Dietary Vitamin K1 Intake and Incident Aortic Valve Stenosis.
    Schultz CJ; Dalgaard F; Bellinge JW; Murray K; Sim M; Connolly E; Blekkenhorst LC; Bondonno CP; Lewis JR; Gislason GH; Tjønneland A; Overvad K; Hodgson JM; Bondonno NP · Arteriosclerosis, thrombosis, and vascular biology · 2024
    Cohort study55,545 participantsCardiovascular Support forVitamin K
  31. Association between vitamin K1 intake and mortality in the Danish Diet, Cancer, and Health cohort.
    Palmer CR; Bellinge JW; Dalgaard F; Sim M; Murray K; Connolly E; Blekkenhorst LC; Bondonno CP; Croft KD; Gislason G; Tjønneland A; Overvad K; Schultz C; Lewis JR; Hodgson JM; Bondonno NP · European journal of epidemiology · 2021
    Cohort study56,048 participantsCardiovascular Support forVitamin K
  32. Effects of boron supplementation on the severity and duration of pain in primary dysmenorrhea.
    Nikkhah S; Dolatian M; Naghii MR; Zaeri F; Taheri SM · Complementary therapies in clinical practice · 2015
    Randomized trial113 participantsGeneral Health forBoron
  33. Efficacy and safety of tavaborole topical solution, 5%, a novel boron-based antifungal agent, for the treatment of toenail onychomycosis: Results from 2 randomized phase-III studies.
    Elewski BE; Aly R; Baldwin SL; González Soto RF; Rich P; Weisfeld M; Wiltz H; Zane LT; Pollak R · Journal of the American Academy of Dermatology · 2015
    Randomized trialGeneral Health forBoron
  34. The efficacy and safety of tavaborole, a novel, boron-based pharmaceutical agent: phase 2 studies conducted for the topical treatment of toenail onychomycosis.
    Toledo-Bahena ME; Bucko A; Ocampo-Candiani J; Herz-Ruelas ME; Jones TM; Jarratt MT; Pollak RA; Zane LT · Journal of drugs in dermatology : JDD · 2015
    Clinical trial336 participantsGeneral Health forBoron
  35. Boron neutron capture therapy (BNCT) for glioblastoma multiforme: a phase II study evaluating a prolonged high-dose of boronophenylalanine (BPA).
    Henriksson R; Capala J; Michanek A; Lindahl SA; Salford LG; Franzén L; Blomquist E; Westlin JE; Bergenheim AT; Swedish Brain Tumour Study Group · Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology · 2009
    Single-arm trial30 participantsGeneral Health forBoron
  36. Effects of Calcium Fructoborate on Levels of C-Reactive Protein, Total Cholesterol, Low-Density Lipoprotein, Triglycerides, IL-1β, IL-6, and MCP-1: a Double-blind, Placebo-controlled Clinical Study
    Otilia-Constantina Rogoveanu, George Dan Mogosanu, Cornelia Bejenaru, Ludovic Everard Bejenaru, Octavian Croitoru, Johny Neamtu, Zbigniew Pietrzkowski, Tania Reyes-Izquierdo, Andrei Bita, Iulia Daria Scorei, Romulus Ion Scorei · Biological Trace Element Research · 2015
    Randomized trial78 participantsGeneral Health forBoron
  37. Associations of selenium status with all-cause and cause-specific mortality: a systematic review and meta-analysis of cohort studies.
    Cui Z; Xie R; Lu X; Schomburg L; Brenner H; Schöttker B · Redox biology · 2025
    Meta-analysis95 participants20 studies pooledGeneral Health forSelenium
  38. Dietary Antioxidants, Circulating Antioxidant Concentrations, Total Antioxidant Capacity, and Risk of All-Cause Mortality: A Systematic Review and Dose-Response Meta-Analysis of Prospective Observational Studies.
    Jayedi A; Rashidy-Pour A; Parohan M; Zargar MS; Shab-Bidar S · Advances in nutrition (Bethesda, Md.) · 2019
    Meta-analysis507,251 participants41 studies pooledGeneral Health forSelenium
  39. The efficacy and safety of selenium supplementation versus placebo in the treatment of Graves' orbitopathy: A systematic review and meta-analysis of randomised controlled trials.
    Sharabati I; Qafesha RM; Hindawi MD; Amro S; Ayesh BM · Clinical endocrinology · 2024
    Meta-analysis4 studies pooledGeneral Health forSelenium
  40. Associations of plasma metal concentrations with the risks of all-cause and cardiovascular disease mortality in Chinese adults.
    Shi L; Yuan Y; Xiao Y; Long P; Li W; Yu Y; Liu Y; Liu K; Wang H; Zhou L; Yang H; Li X; He M; Wu T · Environment international · 2021
    Cohort study6,155 participantsGeneral Health forSelenium
  41. Updates on clinical studies of selenium supplementation in radiotherapy.
    Puspitasari IM; Abdulah R; Yamazaki C; Kameo S; Nakano T; Koyama H · Radiation oncology (London, England) · 2015
    Systematic review16 studies pooledGeneral Health forSelenium
  42. Dietary vitamin K intake associates with reduced all-cause mortality in non-alcoholic fatty liver disease patients.
    Huang Y; Zhu X; Han L; Hu H · Scientific reports · 2025
    Cohort study7,857 participantsGeneral Health forVitamin K
  43. Vitamin K status, cardiovascular disease, and all-cause mortality: a participant-level meta-analysis of 3 US cohorts.
    Shea MK; Barger K; Booth SL; Matuszek G; Cushman M; Benjamin EJ; Kritchevsky SB; Weiner DE · The American journal of clinical nutrition · 2020
    Meta-analysis3,891 participants3 studies pooledGeneral Health forVitamin K
  44. The Effect of Topical Vitamin K1 on the Treatment of Cetuximab-Induced Skin Rashes in Metastatic Colorectal Cancer Patients.
    Roayaei M; Rezaei M; Najafizade N · Advanced biomedical research · 2024
    Randomized trial49 participantsGeneral Health forVitamin K
  45. Effect of vitamin K on improving post‑kidney transplant outcomes: a meta‑analysis.
    Sun Z; Zhu K; Liang G; Yan F; Chao S; Jia L; Niu Y · Experimental and therapeutic medicine · 2023
    Meta-analysis7 studies pooledGeneral Health forVitamin K
  46. Vitamin K1 intake is associated with lower risk for all-cause and cardiovascular disease mortality in community-dwelling older Australian women.
    Dupuy M; Radavelli-Bagatini S; Zhong L; Dalla Via J; Zhu K; Blekkenhorst LC; Bondonno NP; Linneberg A; Bellinge JW; Schultz C; Courtney W; Prince RL; Hodgson JM; Lewis JR; Sim M · Nutrition, metabolism, and cardiovascular diseases : NMCD · 2024
    Cohort study1,436 participantsGeneral Health forVitamin K
  47. Effectiveness of sodium bicarbonate and zinc chloride mouthwashes in the treatment of oral mucositis and quality of life in patients with cancer under chemotherapy.
    Mohammadi F; Oshvandi K; Kamallan SR; Khazaei S; Ranjbar H; Ahmadi-Motamayel F; Gillespie M; Jenabi E; Vafaei SY · Nursing open · 2022
    Randomized trial144 participantsGeneral Health forZinc
  48. Zinc supplementation in young children with acute diarrhea in India.
    Sazawal S; Black RE; Bhan MK; Bhandari N; Sinha A; Jalla S · The New England journal of medicine · 1995
    Randomized trial937 participantsGeneral Health forZinc
  49. Associations of mortality with ocular disorders and an intervention of high-dose antioxidants and zinc in the Age-Related Eye Disease Study: AREDS Report No. 13.
    Clemons TE; Kurinij N; Sperduto RD; AREDS Research Group · Archives of ophthalmology (Chicago, Ill. : 1960) · 2004
    Randomized trial4,753 participantsGeneral Health forZinc
  50. Effects of zinc and probiotic co-supplementation on inflammation, gastrointestinal symptoms, quality of life, and mood in irritable bowel syndrome patients.
    Rezazadegan M; Soheilipour M; Amani R · Scientific reports · 2026
    Randomized trial84 participantsGeneral Health forZinc
  51. Effect of zinc sulfate supplementation on premenstrual syndrome and health-related quality of life: Clinical randomized controlled trial.
    Siahbazi S; Behboudi-Gandevani S; Moghaddam-Banaem L; Montazeri A · The journal of obstetrics and gynaecology research · 2018
    Randomized trial142 participantsGeneral Health forZinc
  52. Effects of selenium supplementation on selenoprotein gene expression and response to influenza vaccine challenge: a randomised controlled trial.
    Goldson AJ; Fairweather-Tait SJ; Armah CN; Bao Y; Broadley MR; Dainty JR; Furniss C; Hart DJ; Teucher B; Hurst R · PloS one · 2011
    Randomized trial119 participantsImmunity forSelenium
  53. Effect of selenium on immune response against hepatitis B vaccine with accelerated method in insulin-dependent diabetes mellitus patients.
    Janbakhsh A; Mansouri F; Vaziri S; Sayad B; Afsharian M; Rahimi M; Shahebrahimi K; Salari F · Caspian journal of internal medicine · 2013
    Randomized trial62 participantsImmunity forSelenium
  54. Chemoprevention trial of human hepatitis with selenium supplementation in China.
    Yu SY; Li WG; Zhu YJ; Yu WP; Hou C · Biological trace element research · 1990
    Non-randomized trial20,847 participantsImmunity forSelenium
  55. Selenium nanoparticles as adjunctive therapy in sepsis: A pilot randomized clinical trial.
    Gu WJ; Huang W; Zhao FZ; Yuan XK; Jin K; Chen JL; Zhang CY; Huang Y; He L; Zhuang H; Yin HY; Chen T · Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy · 2026
    Randomized trial70 participantsImmunity forSelenium
  56. Selenium supplementation in patients with autoimmune thyroiditis decreases thyroid peroxidase antibodies concentrations.
    Gärtner R; Gasnier BC; Dietrich JW; Krebs B; Angstwurm MW · The Journal of clinical endocrinology and metabolism · 2002
    Randomized trial70 participantsImmunity forSelenium
  57. Depressed immune response to tetanus in children with vitamin A deficiency.
    Semba RD; Muhilal; Scott AL; Natadisastra G; Wirasasmita S; Mele L; Ridwan E; West KP; Sommer A · The Journal of nutrition · 1992
    Randomized trial236 participantsImmunity forVitamin A
  58. Impact of a single megadose of vitamin A at delivery on breastmilk of mothers and morbidity of their infants.
    Roy SK; Islam A; Molla A; Akramuzzaman SM; Jahan F; Fuchs G · European journal of clinical nutrition · 1997
    Randomized trial50 participantsImmunity forVitamin A
  59. Vitamin A supplementation reduces measles morbidity in young African children: a randomized, placebo-controlled, double-blind trial.
    Coutsoudis A; Broughton M; Coovadia HM · The American journal of clinical nutrition · 1991
    Randomized trial60 participantsImmunity forVitamin A
  60. Vitamin A supplementation enhances specific IgG antibody levels and total lymphocyte numbers while improving morbidity in measles.
    Coutsoudis A; Kiepiela P; Coovadia HM; Broughton M · The Pediatric infectious disease journal · 1992
    Randomized trial60 participantsImmunity forVitamin A
  61. Vitamin A supplementation reduces the monocyte chemoattractant protein-1 intestinal immune response of Mexican children.
    Long KZ; Santos JI; Estrada Garcia T; Haas M; Firestone M; Bhagwat J; Dupont HL; Hertzmark E; Rosado JL; Nanthakumar NN · The Journal of nutrition · 2006
    Randomized trial127 participantsImmunity forVitamin A
  62. Vitamin C and contribution to the normal function of the immune system: evaluation of a health claim pursuant to Article 14 of Regulation (EC) No 1924/2006.
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusImmunity forVitamin C
  63. Therapeutic effects of high-dose vitamin C supplementation in patients with COVID-19: a meta-analysis.
    Sun L; Zhao JH; Fan WY; Feng B; Liu WW; Chen RQ; Ban C; Dang AG; Wang M; Luo KT; Zhou GY; Yu FF; Ba Y · Nutrition reviews · 2024
    Meta-analysis2,334 participants14 studies pooledImmunity forVitamin C
  64. Effect of micronutrient supplements on influenza and other respiratory tract infections among adults: a systematic review and meta-analysis.
    Abioye AI; Bromage S; Fawzi W · BMJ global health · 2021
    Meta-analysisImmunity forVitamin C
  65. New evidence for antioxidant properties of vitamin C.
    Vojdani A; Bazargan M; Vojdani E; Wright J · Cancer detection and prevention · 2001
    Randomized trial20 participantsImmunity forVitamin C
  66. Enhanced Vitamin C Delivery: A Systematic Literature Review Assessing the Efficacy and Safety of Alternative Supplement Forms in Healthy Adults.
    Calder PC; Kreider RB; McKay DL · Nutrients · 2025
    Systematic review13 studies pooledImmunity forVitamin C
  67. Vitamin D supplementation to prevent acute respiratory infections: individual participant data meta-analysis.
    Martineau AR; Jolliffe DA; Greenberg L; Aloia JF; Bergman P; Dubnov-Raz G; Esposito S; Ganmaa D; Ginde AA; Goodall EC; Grant CC; Janssens W; Jensen ME; Kerley CP; Laaksi I; Manaseki-Holland S; Mauger D; Murdoch DR; Neale R; Rees JR; Simpson S; Stelmach I; Trilok Kumar G; Urashima M; Camargo CA; Griffiths CJ; Hooper RL · Health technology assessment (Winchester, England) · 2020
    Meta-analysis11,321 participants25 studies pooledImmunity forVitamin D
  68. Association Between Vitamin D and Influenza: Meta-Analysis and Systematic Review of Randomized Controlled Trials.
    Zhu Z; Zhu X; Gu L; Zhan Y; Chen L; Li X · Frontiers in nutrition · 2022
    Meta-analysis4,859 participants10 studies pooledImmunity forVitamin D
  69. Vitamin D3 and deconvoluting a rash.
    Ernst MK; Evans ST; Techner JM; Rothbaum RM; Christensen LF; Onay UV; Biyashev D; Demczuk MM; Nguyen CV; Honda KS; McCormick TS; Tsoi LC; Gudjonsson JE; Cooper KD; Lu KQ · JCI insight · 2023
    Randomized trial28 participantsImmunity forVitamin D
  70. Effect of vitamin D3 supplementation on cellular immunity and inflammatory markers in COVID-19 patients admitted to the ICU.
    Bychinin MV; Klypa TV; Mandel IA; Yusubalieva GM; Baklaushev VP; Kolyshkina NA; Troitsky AV · Scientific reports · 2022
    Randomized trial110 participantsImmunity forVitamin D
  71. Current opinion on the role of vitamin D supplementation in respiratory infections and asthma/COPD exacerbations: A need to establish publication guidelines for overcoming the unpublished data.
    Anitua E; Tierno R; Alkhraisat MH · Clinical nutrition (Edinburgh, Scotland) · 2022
    Meta-analysis50,554 participants65 studies pooledImmunity forVitamin D
  72. Nutrient supplementation for prevention of viral respiratory tract infections in healthy subjects: A systematic review and meta-analysis.
    Vlieg-Boerstra B; de Jong N; Meyer R; Agostoni C; De Cosmi V; Grimshaw K; Milani GP; Muraro A; Oude Elberink H; Pali-Schöll I; Roduit C; Sasaki M; Skypala I; Sokolowska M; van Splunter M; Untersmayr E; Venter C; O'Mahony L; Nwaru BI · Allergy · 2022
    Meta-analysis199,055 participants115 studies pooledImmunity forZinc
  73. Zinc supplementation reduces the incidence of acute lower respiratory infections in infants and preschool children: a double-blind, controlled trial.
    Sazawal S; Black RE; Jalla S; Mazumdar S; Sinha A; Bhan MK · Pediatrics · 1998
    Randomized trial609 participantsImmunity forZinc
  74. A randomized controlled trial of zinc supplementation in the treatment of acute respiratory tract infection in Thai children.
    Rerksuppaphol S; Rerksuppaphol L · Pediatric reports · 2020
    Randomized trial64 participantsImmunity forZinc
  75. The effect of zinc and vitamin A supplementation on immune response in an older population.
    Fortes C; Forastiere F; Agabiti N; Fano V; Pacifici R; Virgili F; Piras G; Guidi L; Bartoloni C; Tricerri A; Zuccaro P; Ebrahim S; Perucci CA · Journal of the American Geriatrics Society · 1998
    Randomized trial136 participantsImmunity forZinc
  76. The role of specific nutrients in preventing immune system and blood cell disorders: an umbrella review.
    Vecchietti A; Strano P; Minutolo G; Grieco V; Cappuccio G; Granvillano G; Confalonieri L; Briganti GL; Raso E; Chimienti M; Pellegrini M; Mercogliano M; Spatari G; Lugli C; Urbano T; Lorenzon A · Journal of preventive medicine and hygiene · 2026
    Systematic review13 studies pooledImmunity forZinc