Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.
- Vitamin D Supplementation Ameliorates Metabolic Dysfunction in Patients with PCOS: A SystematicReview of RCTs and Insight into the Underlying Mechanism.
Guo S; Tal R; Jiang H; Yuan T; Liu Y · International journal of endocrinology · 2022
Meta-analysis824 participants13 studies pooledflagTestosterone Support forscienceVitamin D
- Vitamin D for the management of multiple sclerosis.
Jagannath VA; Filippini G; Di Pietrantonj C; Asokan GV; Robak EW; Whamond L; Robinson SA · The Cochrane database of systematic reviews · 2018
Meta-analysis933 participants12 studies pooledflagEnergy forscienceVitamin D
- The Effect of Vitamin D Supplementation on the Androgenic Profile in Patients with Polycystic Ovary Syndrome: A Systematic Review and Meta-Analysis of Clinical Trials.
Azadi-Yazdi M; Nadjarzadeh A; Khosravi-Boroujeni H; Salehi-Abargouei A · Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme · 2017
Meta-analysis183 participants6 studies pooledflagTestosterone Support forscienceVitamin D
- Vitamin D levels and menopause-related symptoms.
LeBlanc ES; Desai M; Perrin N; Wactawski-Wende J; Manson JE; Cauley JA; Michael YL; Tang J; Womack C; Song Y; Johnson KC; O'Sullivan MJ; Woods N; Stefanick ML · Menopause (New York, N.Y.) · 2015
Cross-sectional study530 participantsflagEnergy forscienceVitamin D
- Effect of vitamin D on pregnancy in women with polycystic ovary syndrome: retrospective and prospective studies.
Piao C; Li J; Liang C; Zhang J; Li X; Zhao Z; Wang K · Reproductive biomedicine online · 2024
OtherflagTestosterone Support forscienceVitamin D
- Vitamin D Supplementation in Adolescents and Young Adults With Juvenile Systemic Lupus Erythematosus for Improvement in Disease Activity and Fatigue Scores: A Randomized, Double-Blind, Placebo-Controlled Trial.
Lima GL; Paupitz J; Aikawa NE; Takayama L; Bonfa E; Pereira RM · Arthritis care & research · 2016
Randomized trial40 participantsflagEnergy forscienceVitamin D
- Androgens and hirsutism score of overweight women with polycystic ovary syndrome improved after vitamin D treatment: A randomized placebo controlled clinical trial.
Al-Bayyari N; Al-Domi H; Zayed F; Hailat R; Eaton A · Clinical nutrition (Edinburgh, Scotland) · 2021
Randomized trial60 participantsflagTestosterone Support forscienceVitamin D
- Effect of Vitamin D Supplementation on Fatigue in Multiple Sclerosis: A Systematic Review and Meta-Analysis.
López-Muñoz P; Torres-Costoso AI; Fernández-Rodríguez R; Guzmán-Pavón MJ; de Arenas-Arroyo SN; Basco-López JÁ; Reina-Gutiérrez S · Nutrients · 2023
Meta-analysis345 participants5 studies pooledflagEnergy forscienceVitamin D
- Effect of Two Different Doses of Vitamin D Supplementation on Metabolic Profiles of Insulin-Resistant Patients with Polycystic Ovary Syndrome.
Jamilian M; Foroozanfard F; Rahmani E; Talebi M; Bahmani F; Asemi Z · Nutrients · 2018
Randomized trial90 participantsflagTestosterone Support forscienceVitamin D
- Vitamin D in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome After COVID-19 or Vaccination: A Randomized Controlled Trial.
Kodama S; Nakata M; Konishi N; Yoshino M; Fujisawa A; Naganuma M; Kobayashi Y; Hirai Y; Kitagawa A; Miyokawa M; Mishima R; Teramukai S; Fukushima M · Nutrients · 2026
Randomized trial91 participantsflagEnergy forscienceVitamin D
- Supplementation with vitamin D does not increase serum testosterone levels in healthy males.
Jorde R; Grimnes G; Hutchinson MS; Kjærgaard M; Kamycheva E; Svartberg J · Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme · 2014
Randomized trialflagTestosterone Support forscienceVitamin D
- The effects of vitamin D supplementation on disease activity and fatigue in Libyan rheumatoid arthritis patients.
Elfituri S · Reumatologia · 2024
Randomized trial68 participantsflagEnergy forscienceVitamin D
- Vitamin D and calcium supplementation, skeletal muscle strength and serum testosterone in young healthy adult males: Randomized control trial.
Saha S; Goswami R; Ramakrishnan L; Vishnubhatla S; Mahtab S; Kar P; Srinivasan S; Singh N; Singh U · Clinical endocrinology · 2019
Randomized trial228 participantsflagTestosterone Support forscienceVitamin D
- Role of vitamin D as adjuvant therapy on multiple sclerosis: an updated systematic review and meta-analysis of randomized controlled trials.
Serag I; Abouzid M; Alsaadany KR; Hendawy M; Ali HT; Yaseen Y; Moawad MHED · European journal of medical research · 2025
Meta-analysis1,903 participants21 studies pooledflagEnergy forscienceVitamin D
- The effect of vitamin D supplementation in combination with low-calorie diet on anthropometric indices and androgen hormones in women with polycystic ovary syndrome: a double-blind, randomized, placebo-controlled trial.
Jafari-Sfidvajani S; Ahangari R; Hozoori M; Mozaffari-Khosravi H; Fallahzadeh H; Nadjarzadeh A · Journal of endocrinological investigation · 2018
Randomized trial60 participantsflagTestosterone Support forscienceVitamin D
- Effect of Vitamin D Supplementation on the Prognosis of Post-stroke Fatigue: A Retrospective Cohort Study.
Wang L; Zhao XM; Wang FY; Wu JC; Wang Y · Frontiers in neurology · 2021
Cohort study139 participantsflagEnergy forscienceVitamin D
- Associations of vitamin D status and vitamin D-related polymorphisms with sex hormones in older men.
Rafiq R; van Schoor NM; Sohl E; Zillikens MC; Oosterwerff MM; Schaap L; Lips P; de Jongh RT · The Journal of steroid biochemistry and molecular biology · 2017
Cohort study643 participantsflagTestosterone Support forscienceVitamin D
- The effect of home-based aerobic training and vitamin D supplementation on fatigue and quality of life in patients with multiple sclerosis during COVID-19 outbreak.
Bahmani E; Hoseini R; Amiri E · Science & sports · 2022
Randomized trial40 participantsflagEnergy forscienceVitamin D
- Vitamin D Supplementation and Testosterone Levels in Breast Cancer Survivors.
Minopoli A; Di Gennaro P; Porciello G; Palumbo E; Vitale S; Grimaldi M; Pica R; Falzone L; Montagnese C; de Falco R; Crispo A; Giannascoli D; Di Capua L; Meola S; Pinto M; De Laurentiis M; Di Lauro V; Ferraù F; Catalano F; Messina F; D'Aiuto M; Rinaldo M; Montesarchio V; Gatti D; Steffan A; Massarut S; Polesel J; Libra M; Cavalcanti E; Celentano E; Augustin LSA · International journal of molecular sciences · 2025
Randomized trial253 participantsflagTestosterone Support forscienceVitamin D
- Fatigue and Vitamin D Status in Frail Elderly with and without Cancer, and Healthy Controls of Different Ages: Results from the IMAGE Study.
Dahlén E; Hedman C; Mily A; Alisjahbana A; Spulber G; Holmström-Edstedt J; Bergman P; Buggert M; Björkhem-Bergman L · Gerontology · 2025
Cohort study273 participantsflagEnergy forscienceVitamin D
- Joint association of serum 25-hydroxyvitamin D concentration and body mass index on the acceleration of clinical biomarker-based biological aging.
Pan Z; Zeng J; Chen Z; Chen S; Yang J; Li H; Wang S; Wang J; Li N; Gong Y; Liu M; Li C · The journals of gerontology. Series A, Biological sciences and medical sciences · 2026
Cohort study389,217 participantsflagAnti-Aging forscienceVitamin D
- Serum 25-Hydroxyvitamin D Levels as an Aging Marker: Strong Associations With Age and All-Cause Mortality Independent From Telomere Length, Epigenetic Age Acceleration, and 8-Isoprostane Levels.
Schöttker B; Hagen L; Zhang Y; Gào X; Holleczek B; Gao X; Brenner H · The journals of gerontology. Series A, Biological sciences and medical sciences · 2019
Cohort study9,940 participantsflagAnti-Aging forscienceVitamin D
- Sex-specific associations of serum 25-hydroxyvitamin D concentrations with incident sarcopenia in older adults: A 2-year follow-up study.
Song S; Lim JY; Kim M; Won CW; Park HY · The journal of nutrition, health & aging · 2025
Cohort study1,292 participantsflagAnti-Aging forscienceVitamin D
- Vitamin D deficit is associated with accelerated brain aging in the general population.
Terock J; Bonk S; Frenzel S; Wittfeld K; Garvert L; Hosten N; Nauck M; Völzke H; Van der Auwera S; Grabe HJ · Psychiatry research. Neuroimaging · 2022
Cross-sectional study1,865 participantsflagAnti-Aging forscienceVitamin D
- Vitamin D intake is associated with dementia risk in the Washington Heights-Inwood Columbia Aging Project (WHICAP).
Zhao C; Tsapanou A; Manly J; Schupf N; Brickman AM; Gu Y · Alzheimer's & dementia : the journal of the Alzheimer's Association · 2021
Cohort study1,759 participantsflagAnti-Aging forscienceVitamin D
- Vitamin D deficiency and C-reactive protein: a bidirectional Mendelian randomization study.
Zhou A; Hyppönen E · International journal of epidemiology · 2023
Observational study294,970 participantsflagAnti-Inflammatory Support forscienceVitamin D
- Vitamin D in Children With Inflammatory Bowel Disease: A Randomized Controlled Clinical Trial.
El Amrousy D; El Ashry H; Hodeib H; Hassan S · Journal of clinical gastroenterology · 2021
Randomized trial120 participantsflagAnti-Inflammatory Support forscienceVitamin D
- Vitamin D supplementation reduces infection rate and promotes wound healing in patients with diabetic foot ulcers.
Gao YQ; Gao YH; Xing JH · World journal of diabetes · 2025
Randomized trial120 participantsflagAnti-Inflammatory Support forscienceVitamin D
- Associations of C-reactive Protein with 25-hydroxyvitamin D in 24 Specific Diseases: A Cross-sectional Study from NHANES.
Yang F; Sun M; Sun C; Li J; Yang X; Bi C; Wang M; Pu L; Wang J; Wang C; Xie M; Yao Y; Jin L · Scientific reports · 2020
Cross-sectional study9,809 participantsflagAnti-Inflammatory Support forscienceVitamin D
- Combined effects of vitamin D deficiency and systemic inflammation on all-cause mortality and cause-specific mortality in older adults.
Zhang C; Cui J; Li S; Shen J; Luo X; Yao Y; Shi H · BMC geriatrics · 2024
Cohort study3,072 participantsflagAnti-Inflammatory Support forscienceVitamin D
- Vitamin D supplementation for prevention of mortality in adults.
Bjelakovic G; Gluud LL; Nikolova D; Whitfield K; Wetterslev J; Simonetti RG; Bjelakovic M; Gluud C · The Cochrane database of systematic reviews · 2014
Meta-analysis95,286 participants159 studies pooledflagGeneral Health forscienceVitamin D
- Effect of vitamin D on gastrointestinal symptoms and health-related quality of life in irritable bowel syndrome patients: a randomized double-blind clinical trial.
Abbasnezhad A; Amani R; Hajiani E; Alavinejad P; Cheraghian B; Ghadiri A · Neurogastroenterology and motility · 2018
Randomized trial90 participantsflagGeneral Health forscienceVitamin D
- The impact of vitamin D administration on mortality in COVID-19 patients: a systematic review and meta-analysis of randomized controlled trials.
Kow CS; Ramachandram DS; Hasan SS; Wong Z; Thiruchelvam K · Inflammopharmacology · 2024
Meta-analysis2,495 participants19 studies pooledflagGeneral Health forscienceVitamin D
- Vitamin D Status and Mortality: A Systematic Review of Observational Studies.
Heath AK; Kim IY; Hodge AM; English DR; Muller DC · International journal of environmental research and public health · 2019
Systematic review84 studies pooledflagGeneral Health forscienceVitamin D
- Meta-analysis of long-term vitamin D supplementation on overall mortality.
Zheng Y; Zhu J; Zhou M; Cui L; Yao W; Liu Y · PloS one · 2014
Meta-analysis42 studies pooledflagGeneral Health forscienceVitamin D
- Vitamin D supplementation to prevent acute respiratory infections: individual participant data meta-analysis.
Martineau AR; Jolliffe DA; Greenberg L; Aloia JF; Bergman P; Dubnov-Raz G; Esposito S; Ganmaa D; Ginde AA; Goodall EC; Grant CC; Janssens W; Jensen ME; Kerley CP; Laaksi I; Manaseki-Holland S; Mauger D; Murdoch DR; Neale R; Rees JR; Simpson S; Stelmach I; Trilok Kumar G; Urashima M; Camargo CA; Griffiths CJ; Hooper RL · Health technology assessment (Winchester, England) · 2020
Meta-analysis11,321 participants25 studies pooledflagImmunity forscienceVitamin D
- Association Between Vitamin D and Influenza: Meta-Analysis and Systematic Review of Randomized Controlled Trials.
Zhu Z; Zhu X; Gu L; Zhan Y; Chen L; Li X · Frontiers in nutrition · 2022
Meta-analysis4,859 participants10 studies pooledflagImmunity forscienceVitamin D
- Vitamin D3 and deconvoluting a rash.
Ernst MK; Evans ST; Techner JM; Rothbaum RM; Christensen LF; Onay UV; Biyashev D; Demczuk MM; Nguyen CV; Honda KS; McCormick TS; Tsoi LC; Gudjonsson JE; Cooper KD; Lu KQ · JCI insight · 2023
Randomized trial28 participantsflagImmunity forscienceVitamin D
- Effect of vitamin D3 supplementation on cellular immunity and inflammatory markers in COVID-19 patients admitted to the ICU.
Bychinin MV; Klypa TV; Mandel IA; Yusubalieva GM; Baklaushev VP; Kolyshkina NA; Troitsky AV · Scientific reports · 2022
Randomized trial110 participantsflagImmunity forscienceVitamin D
- Current opinion on the role of vitamin D supplementation in respiratory infections and asthma/COPD exacerbations: A need to establish publication guidelines for overcoming the unpublished data.
Anitua E; Tierno R; Alkhraisat MH · Clinical nutrition (Edinburgh, Scotland) · 2022
Meta-analysis50,554 participants65 studies pooledflagImmunity forscienceVitamin D
- Association between plasma 25-OH vitamin D and testosterone levels in men.
Nimptsch K; Platz EA; Willett WC; Giovannucci E · Clinical endocrinology · 2012
Case-control study1,362 participantsflagTestosterone Support forscienceVitamin D
- Causal Link Between Vitamin D and Total Testosterone in Men: A Mendelian Randomization Analysis.
Chen C; Zhai H; Cheng J; Weng P; Chen Y; Li Q; Wang C; Xia F; Wang N; Lu Y · The Journal of clinical endocrinology and metabolism · 2020
Other4,254 participantsflagTestosterone Support forscienceVitamin D