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Adrenal Response Complete Care

INNATE Response Formulas
4.5
★ ★ ★ ★ ★
(119 ratings)
Ashwagandha 250 mg
Rhodiola
Vitamin B5 30 mg
Astragalus 100 mg
Reishi mushroom 200 mg
Product Image
Score69
A broad adaptogen formula led by well-identified ashwagandha and a useful rhodiola amount, balanced by high cost, uneven extract detail, and several safety-fit considerations.
How scoring works
Quantity:90 Tablet(s) • (45 servings)
Goals:
Stress Relief
Brain Health
Cognitive Support
General Health
Energy
Mood Support
Mental Focus
Productivity Boost

Score 69

A broad adaptogen formula led by well-identified ashwagandha and a useful rhodiola amount, balanced by high cost, uneven extract detail, and several safety-fit considerations.
How scoring works
$67.49($1.49 per serving)
Walmart
$ 80.96
iHerb
$ 67.49
Amazon
$ 80.65
Pure Formulas
$ 89.99
Vitacost
$ 89.99
Report prices

Analysis

Branded Sensoril ashwagandha and rhodiola form the strongest part of the formula, supporting stress resilience and mental-fatigue management. L-serine, holy basil, schisandra, reishi, astragalus, magnesium, and pantothenic acid add breadth across related pathways.

The main adaptogen amounts are individually stated, and the ashwagandha form has useful identity detail. Rhodiola, astragalus, and mushroom quality are less defined because active-marker or extraction information is missing.

The blend fits adults seeking broad, non-stimulant stress and energy support rather than a simple single-ingredient product. Its complex ingredient list raises the chance of individual tolerance or medication-fit issues, and the serving is costly for routine use.

Who is it for
  • Adults seeking non-stimulant stress support
  • People managing mental fatigue
  • Users comfortable with a multi-adaptogen formula
Best for
  • Stress resilience
  • Steady energy support
  • Mental-fatigue management

Pros

  • Branded Sensoril ashwagandha
  • Useful rhodiola amount
  • Broad but coherent adaptogen coverage

Cons

  • Several extracts lack marker standardization
  • High cost per serving
  • Complex formula makes individual response harder to predict

Warnings

  • Ashwagandha may affect thyroid function and warrants clinician guidance with thyroid conditions or thyroid medicines
  • Avoid during pregnancy unless a qualified professional specifically approves the formula
  • Ashwagandha has rare liver-injury reports, so stop use and seek advice if liver-related symptoms appear
  • Astragalus may conflict with immune-suppressing medicines
  • The adaptogen blend may cause drowsiness, stomach upset, or sensitivity in some users

Nutrient quality

85 Highest impact

Sensoril ashwagandha and calcium pantothenate are favorable forms, while several botanicals lack standardization. Ashwagandha, rhodiola, serine, and holy basil provide useful blend-level amounts.

.

Ingredient transparency

77 High impact

All listed active ingredients have specific amounts. The supplied data does not include a complete inactive ingredient list.

.

Customer satisfaction

61 Moderate impact

The aggregate satisfaction measure is strong enough to support a favorable first impression. The limited volume and missing feedback themes leave repeat complaints and purpose fit uncertain.

.

Value for money

45 Lower impact

The premium price is difficult to justify despite several thoughtful ingredients. Each serving is very costly for the dose depth provided.

.
Report analysis

Goals

Stress Relief
Impact
Highest effect
A- Goal FitA+ Strength of SupportB+ CoverageB+ Formula Quality
Ashwagandha · 250 mgMagnesium · 40 mgVitamin C · 100 mg

Adrenal Response Complete Care provides 250 mg branded Sensoril ashwagandha, 200 mg rhodiola and 40 mg magnesium and has 115 reviews averaging 4.51, indicating favorable customer satisfaction. NSF distinguishes facility GMP oversight from finished-product certification, so a current product-specific quality mark should be checked rather than assumed.

NIH notes that ashwagandha can cause drowsiness or stomach upset and may affect thyroid function or interact with medicines, so individual safety fit matters.

Study evidence
Ashwagandha Supportive 47 studies
Magnesium Supportive 13 studies
Rhodiola Supportive 16 studies
Brain Health
Impact
Highest effect
B+ Goal FitA+ Strength of SupportB- CoverageB Formula Quality
Magnesium · 40 mgAshwagandha · 250 mg

Adrenal Response Complete Care aligns with Brain Health mainly through Ashwagandha and Rhodiola, while the supplied collection analyses average 70.4 and supplied customer feedback is 4.51 from 115 reviews.

Its strongest feature is dose adequacy, while coverage remains intentionally narrow; it appears better suited to a targeted role within a broader routine.

Study evidence
Ashwagandha Supportive 12 studies
Rhodiola Supportive 8 studies
Cognitive Support
Impact
Highest effect
B+ Goal FitA+ Strength of SupportB- CoverageB Formula Quality
Magnesium · 40 mgAshwagandha · 250 mg

Adrenal Response Complete Care aligns with Cognitive Support mainly through Ashwagandha and Rhodiola, while the supplied collection analyses average 70.4 and supplied customer feedback is 4.51 from 115 reviews.

Its strongest feature is dose adequacy, while coverage remains intentionally narrow; it appears better suited to a targeted role within a broader routine.

Study evidence
Ashwagandha Supportive 17 studies
Rhodiola Supportive 7 studies
General Health
Impact
Highest effect
B+ Goal FitA+ Strength of SupportB- CoverageB Formula Quality
Magnesium · 40 mgAshwagandha · 250 mgVitamin C · 100 mg

Adrenal Response Complete Care aligns with General Health mainly through Ashwagandha and Rhodiola, while the supplied collection analyses average 70.4 and supplied customer feedback is 4.51 from 115 reviews.

Its strongest feature is dose adequacy, while coverage remains intentionally narrow; it appears better suited to a targeted role within a broader routine.

Study evidence
Ashwagandha Supportive 31 studies
Rhodiola Supportive 7 studies
Energy
Impact
Highest effect
B+ Goal FitB+ Strength of SupportB CoverageA- Formula Quality
Vitamin B5 · 30 mgMagnesium · 40 mg

Adrenal Response Complete Care is reasonably aligned with the Energy goal because its highlighted actives include Rhodiola rosea root extract at 200 mg, Sensoril Ashwagandha root & leaf extract at 250 mg, Pantothenic Acid at 30 mg, and Magnesium at 40 mg; evidence quality for the formula as a whole is good.

Customer feedback averages 4.51 out of 5 across 115 reviews; ashwagandha warrants caution during pregnancy and with thyroid, liver, or interacting-medication concerns.

Study evidence
Ashwagandha Supportive 9 studies
Magnesium Supportive 4 studies
Rhodiola Supportive 18 studies
Mood Support
Impact
High effect
B+ Goal FitB- Strength of SupportB+ CoverageB- Formula Quality
Magnesium · 40 mgAshwagandha · 250 mg

Adrenal Response Complete Care from INNATE Response Formulas covers neurotransmitter support, stress-response or HPA-axis support, structural or anti-inflammatory support, producing strong alignment with mood support.

Collection-specific evidence indicates moderate dose adequacy and good form or disclosure quality, with the main limitation being variable evidence across the included actives.

Study evidence
Ashwagandha Supportive 29 studies
Rhodiola Supportive 15 studies

Ingredients

IngredientAmount per serving
Vitamin C (organic Orange)
100 mg
Pantothenic Acid (Calcium D-Pantothenate)
30 mg
Magnesium (S. cerevisiae)
40 mg
Sensoril Ashwagandha root & leaf extract (Withanolides)
250 mg
L-Serine
200 mg
Reishi Mushroom (Purple Corn optimized biomass)
200 mg
Rhodiola rosea root extract
200 mg
Holy Basil leaf extract
175 mg
organic Astragalus
100 mg
organic Schisandra
100 mg
Gluten Free Adults 18–50 Kosher Dairy Free Vegetarian
Report overview
A- Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyF Value

Reported customer feedback averages 4.51 out of 5 across 115 reviews. A clinically studied branded extract provides strong ingredient-form quality; the disclosed amount aligns with the applicable rubric target, while the exact milligram quantity is transparent. Ashwagandha may affect thyroid function and has rare liver-injury reports, so pregnancy, thyroid or liver concerns, and potentially interacting medicines warrant clinician guidance.

Rhodiola · 200 mg OverallScore61
C Active Ingredient Quality & BioavailabilityA Dose, Safety & Label TransparencyF Value

Adrenal Response Complete Care provides 200 mg of Rhodiola rosea root extract, and marker standardization is not documented. The amount is in the target range and individually disclosed. Customer feedback averages 4.51 across 115 reviews; third-party listings report non-GMO and pesticide-testing credentials, while the label advises clinical review during pregnancy, nursing, or when managing a health condition.

A- Active Ingredient Quality & BioavailabilityD+ Dose, Safety & Label TransparencyF Value

D-calcium pantothenate provides a stable and well-absorbed vitamin B5 form. The 30 mg serving meets a basic intake but lacks therapeutic potency. The active amount is costly when normalized to a therapeutic dose, while no controversial additive is shown, though complete excipient details are unavailable.

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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Dual impact of Ashwagandha: Significant cortisol reduction but no effects on perceived stress - A systematic review and meta-analysis.
    Albalawi AA · Nutrition and health · 2025
    Meta-analysis488 participants13 studies pooledStress Relief forAshwagandha
  2. An investigation into the stress-relieving and pharmacological actions of an ashwagandha (Withania somnifera) extract: A randomized, double-blind, placebo-controlled study.
    Lopresti AL; Smith SJ; Malvi H; Kodgule R · Medicine · 2019
    Randomized trial60 participantsStress Relief forAshwagandha
  3. Scientific Opinion on the substantiation of a health claim related to Rhodiola rosea L. extract and reduction of mental fatigue pursuant to Article 13(5) of Regulation (EC) No 1924/2006.
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusStress Relief forRhodiola
  4. The Effectiveness of Rhodiola rosea L. Preparations in Alleviating Various Aspects of Life-Stress Symptoms and Stress-Induced Conditions-Encouraging Clinical Evidence.
    Ivanova Stojcheva E; Quintela JC · Molecules (Basel, Switzerland) · 2022
    Narrative reviewStress Relief Productivity Boost forRhodiola
  5. Acute and Repeated Ashwagandha Supplementation Improves Markers of Cognitive Function and Mood.
    Leonard M; Dickerson B; Estes L; Gonzalez DE; Jenkins V; Johnson S; Xing D; Yoo C; Ko J; Purpura M; Jäger R; Faries M; Kephart W; Sowinski R; Rasmussen CJ; Kreider RB · Nutrients · 2024
    Randomized trial59 participantsBrain Health Cognitive Support Energy forAshwagandha
  6. Effect of ashwagandha (Withania somnifera) extract with Sominone (Somin-On™) to improve memory in adults with mild cognitive impairment: A randomized, double-blind, placebo-controlled study.
    Rai HP; Mishra DN · Journal of psychopharmacology (Oxford, England) · 2025
    Randomized trial40 participantsBrain Health Cognitive Support Mental Focus forAshwagandha
  7. Efficacy of Withania somnifera supplementation on adult's cognition and mood.
    Remenapp A; Coyle K; Orange T; Lynch T; Hooper D; Hooper S; Conway K; Hausenblas HA · Journal of Ayurveda and integrative medicine · 2022
    Randomized trial60 participantsBrain Health Cognitive Support Productivity Boost forAshwagandha
  8. A clinical assessment of the therapeutic effects of Ashwagandha root extract on cognitive performance, sleep, and fatigue in children aged 6-12 years.
    Saxena A; Lopresti A; Sharif M; Elon N; Suri R; Langade DK · Frontiers in nutrition · 2026
    Randomized trial85 participantsBrain Health Mental Focus forAshwagandha
  9. Efficacy and Safety of Ashwagandha Root Extract on Cognitive Functions in Healthy, Stressed Adults: A Randomized, Double-Blind, Placebo-Controlled Study.
    Gopukumar K; Thanawala S; Somepalli V; Rao TSS; Thamatam VB; Chauhan S · Evidence-based complementary and alternative medicine : eCAM · 2022
    Randomized trial130 participantsBrain Health Stress Relief forAshwagandha
  10. Dose-Response Effects of Short-Term Rhodiola rosea (Golden Root Extract) Supplementation on Anaerobic Exercise Performance and Cognitive Function in Resistance-Trained Athletes: A Randomized, Crossover, Double-Blind, and Placebo-Controlled Study.
    Koozehchian MS; Newton AT; Mabrey G; Bonness FM; Rafajlovska R; Naderi A · Nutrients · 2025
    Randomized trial27 participantsBrain Health Mental Focus forRhodiola
  11. A combination of green tea, rhodiola, magnesium and B vitamins modulates brain activity and protects against the effects of induced social stress in healthy volunteers.
    Boyle NB; Billington J; Lawton C; Quadt F; Dye L · Nutritional neuroscience · 2022
    Randomized trial100 participantsBrain Health forRhodiola
  12. Rosenroot (Rhodiola rosea): traditional use, chemical composition, pharmacology and clinical efficacy.
    Panossian A; Wikman G; Sarris J · Phytomedicine : international journal of phytotherapy and phytopharmacology · 2010
    Narrative reviewBrain Health forRhodiola
  13. Rhodiola rosea in stress induced fatigue--a double blind cross-over study of a standardized extract SHR-5 with a repeated low-dose regimen on the mental performance of healthy physicians during night duty.
    Darbinyan V; Kteyan A; Panossian A; Gabrielian E; Wikman G; Wagner H · Phytomedicine : international journal of phytotherapy and phytopharmacology · 2001
    Randomized trial56 participantsBrain Health General Health Productivity Boost forRhodiola
  14. Effects of a Rhodiola rosea extract on mental resource allocation and attention: An event-related potential dual task study.
    Koop T; Dienel A; Heldmann M; Münte TF · Phytotherapy research : PTR · 2021
    Single-arm trial50 participantsBrain Health Cognitive Support forRhodiola
  15. A standardized Ashwagandha root extract alleviates stress, anxiety, and improves quality of life in healthy adults by modulating stress hormones: Results from a randomized, double-blind, placebo-controlled study.
    Majeed M; Nagabhushanam K; Mundkur L · Medicine · 2023
    Randomized trial54 participantsCognitive Support Mental Focus forAshwagandha
  16. Efficacy and safety of ashwagandha root extract in children and adolescents with mild attention-deficit/hyperactivity disorder: a randomized, double-blind, placebo-controlled trial.
    Naik S; Muralidhar G; Rao BS; Agarwal S; Jain M · Journal of medicine and life · 2026
    Randomized trial58 participantsCognitive Support Mental Focus forAshwagandha
  17. Evidence-based efficacy of adaptogens in fatigue, and molecular mechanisms related to their stress-protective activity.
    Panossian A; Wikman G · Current clinical pharmacology · 2009
    Narrative reviewCognitive Support Mental Focus forRhodiola
  18. Central additive effect of Ginkgo biloba and Rhodiola rosea on psychomotor vigilance task and short-term working memory accuracy.
    Al-Kuraishy HM · Journal of intercultural ethnopharmacology · 2016
    Clinical trial112 participantsCognitive Support forRhodiola
  19. Clinical evidence for the adaptogenic effects of Withania somnifera and Rhodiola rosea - A systematic review with molecular interpretation of psychometric outcomes.
    Łuszczak J; Kocki J · Annals of agricultural and environmental medicine : AAEM · 2026
    Systematic review19 studies pooledCognitive Support Stress Relief forRhodiola
  20. A randomised, double-blind, placebo-controlled, parallel-group study of the standardised extract shr-5 of the roots of Rhodiola rosea in the treatment of subjects with stress-related fatigue.
    Olsson EM; von Schéele B; Panossian AG · Planta medica · 2009
    Randomized trial60 participantsCognitive Support Productivity Boost forRhodiola
  21. Effects of multi-herb and ashwagandha root formulas on stress modulation: a randomized, double-blind, placebo-controlled clinical study.
    McKinney E; Stewart J; Kewalramani R; Singh S · Trials · 2026
    Randomized trial186 participantsEnergy Mood Support forAshwagandha
  22. Efficacy and Safety of Low-Dose Ashwagandha Supplementation on Exercise Endurance: A Randomized, Placebo-Controlled, Double-Blind, Clinical Trial.
    Prajapati H; Satia M; Shah D; Basera I; Shah T · Phytotherapy research : PTR · 2026
    Randomized trialEnergy forAshwagandha
  23. Enhancing healthspan with Ashwagandha (Withania somnifera): a comprehensive review of its multifaceted geroprotective benefits.
    Vittal M; Vinciguerra M · Biogerontology · 2025
    Narrative reviewEnergy forAshwagandha
  24. Safety and Efficacy of Ashwagandha Root Extract on Cognition, Energy and Mood Problems in Adults: Prospective, Randomized, Placebo-Controlled Study.
    Kale S; Lopresti A; Suri R; Garg N; Langade D · Journal of psychoactive drugs · 2026
    Randomized trial120 participantsEnergy Productivity Boost forAshwagandha
  25. Magnesium-L-threonate improves sleep quality and daytime functioning in adults with self-reported sleep problems: A randomized controlled trial.
    Hausenblas HA; Lynch T; Hooper S; Shrestha A; Rosendale D; Gu J · Sleep medicine: X · 2025
    Randomized trial80 participantsEnergy forMagnesium
  26. Total magnesium intake and risk of frailty in older women.
    Struijk EA; Fung TT; Bischoff-Ferrari HA; Willett WC; Lopez-Garcia E · Journal of cachexia, sarcopenia and muscle · 2024
    Cohort study81,524 participantsEnergy forMagnesium
  27. Red blood cell magnesium and chronic fatigue syndrome.
    Cox IM; Campbell MJ; Dowson D · Lancet (London, England) · 1991
    Randomized trial32 participantsEnergy forMagnesium
  28. Exercise, magnesium and immune function.
    Laires MJ; Monteiro C · Magnesium research · 2008
    Narrative reviewEnergy forMagnesium
  29. The Effect of Short-Term Rhodiola rosea Supplementation on Simulated Game Time, Perceived Fatigue, and Performance in Basketball Players.
    Wang J; Zhao H; Yu L; Zhao K; Jiang W; Liu S; Dai J; Xu L; Sun P; Yun H; Liu C · Nutrients · 2025
    Randomized trial48 participantsEnergy forRhodiola
  30. Effects of Rhodiola rosea on Physical and Decision-Making Performance in Football Players: A Randomised Controlled Trial.
    Dou Y; Wang Y; Zhang W; Jiang Y; Zhang J; Yang T; Han Z; Li Y; Liu C; Ren D · Nutrients · 2026
    Randomized trial24 participantsEnergy Mental Focus forRhodiola
  31. Combined Effects of Rhodiola Rosea and Caffeine Supplementation on Straight Punch Explosive Power in Untrained and Trained Boxing Volunteers: A Synergistic Approach.
    Tao B; Sun H; Li H; Xu Z; Xu Y; Chen L; Ma C; Zhang X; Yu L; Bao S; Liu C · Metabolites · 2025
    Randomized trial96 participantsEnergy forRhodiola
  32. Rhodiola rosea in Subjects with Prolonged or Chronic Fatigue Symptoms: Results of an Open-Label Clinical Trial.
    Lekomtseva Y; Zhukova I; Wacker A · Complementary medicine research · 2019
    Single-arm trial100 participantsEnergy General Health Stress Relief forRhodiola
  33. Combined Rhodiola rosea and eccentric training boost endurance performance and lower-limb reactive strength in recreationally active women.
    Wang IL; Su Y; Zhang L; Tang M; Chen YM · Frontiers in physiology · 2025
    Randomized trial30 participantsEnergy forRhodiola
  34. A randomized, double blind, placebo controlled study to evaluate the effects of ashwagandha (Withania somnifera) extract on sleep quality in healthy adults.
    Deshpande A; Irani N; Balkrishnan R; Benny IR · Sleep medicine · 2021
    Randomized trial150 participantsGeneral Health forAshwagandha
  35. Effects of Ashwagandha ( Withania somnifera) standardized root extract on physical endurance and VO 2max in healthy adults performing resistance training: An eight-week, prospective, randomized, double-blind, placebo-controlled study.
    Verma N; Gupta SK; Patil S; Tiwari S; Mishra AK · F1000Research · 2024
    Randomized trial80 participantsGeneral Health forAshwagandha
  36. Efficacy of Ashwagandha (Withania somnifera [L.] Dunal) in improving cardiorespiratory endurance in healthy athletic adults.
    Choudhary B; Shetty A; Langade DG · Ayu · 2016
    Randomized trial50 participantsGeneral Health forAshwagandha
  37. Withania somnifera (L.) Dunal as Add-On Therapy for COPD Patients: A Randomized, Placebo-Controlled, Double-Blind Study.
    Singh P; Salman KA; Shameem M; Warsi MS · Frontiers in pharmacology · 2022
    Randomized trial150 participantsGeneral Health forAshwagandha
  38. Effect of Ashwagandha (Withania somnifera) extract on sleep: A systematic review and meta-analysis.
    Cheah KL; Norhayati MN; Husniati Yaacob L; Abdul Rahman R · PloS one · 2021
    Meta-analysis400 participants5 studies pooledGeneral Health Productivity Boost forAshwagandha
  39. Actaea racemosa L. Is More Effective in Combination with Rhodiola rosea L. for Relief of Menopausal Symptoms: A Randomized, Double-Blind, Placebo-Controlled Study.
    Pkhaladze L; Davidova N; Khomasuridze A; Shengelia R; Panossian AG · Pharmaceuticals (Basel, Switzerland) · 2024
    Randomized trial220 participantsGeneral Health forRhodiola
  40. A double-blind, placebo-controlled pilot study of the stimulating and adaptogenic effect of Rhodiola rosea SHR-5 extract on the fatigue of students caused by stress during an examination period with a repeated low-dose regimen.
    Spasov AA; Wikman GK; Mandrikov VB; Mironova IA; Neumoin VV · Phytomedicine : international journal of phytotherapy and phytopharmacology · 2000
    Randomized trialGeneral Health Productivity Boost forRhodiola
  41. [The effect of the preparation rodakson on the psychophysiological and physical adaptation of students to an academic load].
    Spasov AA; Mandrikov VB; Mironova IA · Eksperimental'naia i klinicheskaia farmakologiia · 2000
    Clinical trialGeneral Health forRhodiola
  42. Efficacy and Safety of Ashwagandha (Withania somnifera (L.) Dunal) Root Extract in Improving Memory and Cognitive Functions.
    Choudhary D; Bhattacharyya S; Bose S · Journal of dietary supplements · 2018
    Randomized trial50 participantsMental Focus forAshwagandha
  43. Relationship between Whole-Blood Magnesium and Cognitive Performance among Chinese Adults.
    Lu Z; He R; Zhang Y; Li B; Li F; Fu Y; Rong S · Nutrients · 2023
    Cross-sectional study1,006 participantsMental Focus forMagnesium
  44. Serum Magnesium and Cognitive Function Among Qatari Adults.
    Al-Ghazali K; Eltayeb S; Musleh A; Al-Abdi T; Ganji V; Shi Z · Frontiers in aging neuroscience · 2020
    Cross-sectional study1,000 participantsMental Focus forMagnesium
  45. Magnesium status and attention deficit hyperactivity disorder (ADHD): A meta-analysis.
    Effatpanah M; Rezaei M; Effatpanah H; Effatpanah Z; Varkaneh HK; Mousavi SM; Fatahi S; Rinaldi G; Hashemi R · Psychiatry research · 2019
    Meta-analysisMental Focus forMagnesium
  46. The effect of vitamin D and magnesium supplementation on the mental health status of attention-deficit hyperactive children: a randomized controlled trial.
    Hemamy M; Pahlavani N; Amanollahi A; Islam SMS; McVicar J; Askari G; Malekahmadi M · BMC pediatrics · 2021
    Randomized trial33 participantsMental Focus forMagnesium
  47. The effects of magnesium L-threonate (Magtein®) on cognitive performance and sleep quality in adults: a randomised, double-blind, placebo-controlled trial.
    Lopresti AL; Smith SJ · Frontiers in nutrition · 2026
    Randomized trial100 participantsMental Focus forMagnesium
  48. The effectiveness and efficacy of Rhodiola rosea L.: a systematic review of randomized clinical trials.
    Hung SK; Perry R; Ernst E · Phytomedicine : international journal of phytotherapy and phytopharmacology · 2012
    Systematic review11 studies pooledMental Focus forRhodiola
  49. Effects of Rhodiola rosea supplementation on mental performance, physical capacity, and oxidative stress biomarkers in healthy men.
    Jówko E; Sadowski J; Długołęcka B; Gierczuk D; Opaszowski B; Cieśliński I · Journal of sport and health science · 2022
    Randomized trial26 participantsMental Focus Productivity Boost forRhodiola
  50. A proprietary herbal extract of ashwagandha root for stress and anxiety in healthy adults: a randomized, double-blind, three-arm, placebo-controlled efficacy and safety study.
    West RE; Biswas A; Rao R; Tayade H; Ademola J · Journal of medicine and life · 2026
    Randomized trial141 participantsMood Support forAshwagandha
  51. Safety and efficacy of Withania somnifera for anxiety and insomnia: Systematic review and meta-analysis.
    Fatima K; Malik J; Muskan F; Raza G; Waseem A; Shahid H; Jaffery SF; Khan U; Zaheer MK; Shaikh Y; Rashid AM · Human psychopharmacology · 2024
    Meta-analysis254 participants5 studies pooledMood Support forAshwagandha
  52. A prospective, randomized double-blind, placebo-controlled study of safety and efficacy of a high-concentration full-spectrum extract of ashwagandha root in reducing stress and anxiety in adults.
    Chandrasekhar K; Kapoor J; Anishetty S · Indian journal of psychological medicine · 2013
    Randomized trial64 participantsMood Support Stress Relief forAshwagandha
  53. Medicinal herbs for the treatment of anxiety: A systematic review and network meta-analysis.
    Zhang W; Yan Y; Wu Y; Yang H; Zhu P; Yan F; Zhao R; Tian P; Wang T; Fan Q; Su Z · Pharmacological research · 2022
    Meta-analysis29 participants29 studies pooledMood Support forAshwagandha
  54. Efficacy of Pharmacological Interventions in Milder Depression: A Systematic Review and Meta-Analysis.
    Urata M; Sakurai H; Ueno F; Maruki T; Tada T; Uchida T; Matsumoto Y; Murao M; Tomita M; Baba H; Kato M; Tsuboi T; Watanabe K · Neuropsychopharmacology reports · 2025
    Meta-analysis1,049 participants2 studies pooledMood Support forRhodiola
  55. The Effect of Acute Rhodiola rosea Ingestion on Exercise Heart Rate, Substrate Utilisation, Mood State, and Perceptions of Exertion, Arousal, and Pleasure/Displeasure in Active Men.
    Duncan MJ; Clarke ND · Journal of sports medicine (Hindawi Publishing Corporation) · 2015
    Clinical trial10 participantsMood Support forRhodiola
  56. Herbal medicine for depression, anxiety and insomnia: a review of psychopharmacology and clinical evidence.
    Sarris J; Panossian A; Schweitzer I; Stough C; Scholey A · European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology · 2012
    Systematic review66 studies pooledMood Support forRhodiola
  57. Medicinal Plants in the Treatment of Depression. II: Evidence from Clinical Trials.
    Moragrega I; Ríos JL · Planta medica · 2022
    Systematic reviewMood Support forRhodiola
  58. Multicenter, open-label, exploratory clinical trial with Rhodiola rosea extract in patients suffering from burnout symptoms.
    Kasper S; Dienel A · Neuropsychiatric disease and treatment · 2020
    Single-arm trial118 participantsMood Support forRhodiola
  59. Clinical evaluation of the pharmacological impact of ashwagandha root extract on sleep in healthy volunteers and insomnia patients: A double-blind, randomized, parallel-group, placebo-controlled study.
    Langade D; Thakare V; Kanchi S; Kelgane S · Journal of ethnopharmacology · 2021
    Randomized trial80 participantsProductivity Boost forAshwagandha
  60. Effect of standardized aqueous extract of Withania somnifera on tests of cognitive and psychomotor performance in healthy human participants.
    Pingali U; Pilli R; Fatima N · Pharmacognosy research · 2014
    Randomized trial20 participantsProductivity Boost forAshwagandha
  61. Shoden promotes Relief from stress and anxiety: A randomized, double-blind, placebo-controlled study on healthy subjects with high stress levels.
    Mishra DN; Kumar M · Heliyon · 2024
    Randomized trial60 participantsStress Relief forAshwagandha
  62. Adaptogenic and Anxiolytic Effects of Ashwagandha Root Extract in Healthy Adults: A Double-blind, Randomized, Placebo-controlled Clinical Study.
    Salve J; Pate S; Debnath K; Langade D · Cureus · 2020
    Randomized trial60 participantsStress Relief forAshwagandha
  63. Role of magnesium supplementation in the treatment of depression: A randomized clinical trial.
    Tarleton EK; Littenberg B; MacLean CD; Kennedy AG; Daley C · PloS one · 2017
    Randomized trial126 participantsStress Relief forMagnesium
  64. Effects of Intravenous Esketamine or Magnesium Sulfate on Early Postoperative Negative Emotions and Pain in Patients Undergoing Endoscopic Sinus Surgery: A Randomized Controlled Trial.
    Wang L; Zhou J; Liu Q; Qian K; Wang L; Xie C · Therapeutics and clinical risk management · 2026
    Randomized trial137 participantsStress Relief forMagnesium
  65. Effect of short-term magnesium supplementation on anxiety, depression and sleep quality in patients after open-heart surgery.
    Saba S; Faizi F; Sepandi M; Nehrir B · Magnesium research · 2022
    Non-randomized trial60 participantsStress Relief forMagnesium
  66. Effects of dry needling compared to magnesium infiltration in trigger points for patients with myofascial pain syndrome: a randomized controlled study in Tunisia.
    Dhouibi J; Moncer R; Kalbousi N; Gaddour M; Laayouni S; Ouanes W; Kacem B; Jemni S · Korean journal of family medicine · 2026
    Randomized trial45 participantsStress Relief forMagnesium
  67. Effect of magnesium and vitamin B6 supplementation on mental health and quality of life in stressed healthy adults: Post-hoc analysis of a randomised controlled trial.
    Noah L; Dye L; Bois De Fer B; Mazur A; Pickering G; Pouteau E · Stress and health : journal of the International Society for the Investigation of Stress · 2021
    Randomized trialStress Relief forMagnesium
  68. Stress management and the role of Rhodiola rosea: a review.
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