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Vitamin D3 5000 IU

Spring Valley
4.8
★ ★ ★ ★ ★
(7573 ratings)
Vitamin D 5000 IU
Product Image
Score80
Best suited to general health, with the clearest benefits coming from the disclosed active ingredients. The duplicate vitamin D entries make the active disclosure ambiguous, and the amount may exceed some users' maintenance needs.
How scoring works
Quantity:100 Softgel(s) • (100 servings)
Goals:
General Health
Immunity
Testosterone Support
Anti-Aging
Anti-Inflammatory Support
Energy

Score 80

Best suited to general health, with the clearest benefits coming from the disclosed active ingredients. The duplicate vitamin D entries make the active disclosure ambiguous, and the amount may exceed some users' maintenance needs.
How scoring works
$5.94($0.05 per serving)
Walmart
$ 5.94
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Analysis

An economical softgel supplies a substantial D3 amount in a suitable delivery format. The duplicate vitamin D entries make the active disclosure ambiguous, and the amount may exceed some users' maintenance needs.

Vitamin D3 directly supports a foundational nutrient need tied to immune function, calcium handling, and bone maintenance. The cholecalciferol softgel uses a suitable form and lipid-based delivery. The 5000 IU serving is concentrated and may fit people with a demonstrated need better than routine unsupervised use.

Vitamin D3 may improve fatigue or muscle weakness when low status is the underlying problem. The softgel provides clear cholecalciferol dosing in a format suited to a fat-soluble vitamin. The amount exceeds the adult daily upper intake level used for routine unsupervised intake.

Who is it for
  • People seeking general health support
  • People seeking immunity support
  • People seeking testosterone support support
Best for
  • General Health
  • Immunity
  • Testosterone Support

Pros

  • An economical softgel supplies a substantial D3 amount in a suitable delivery format.
  • The duplicate vitamin D entries make the active disclosure ambiguous, and the amount may exceed some users' maintenance needs.
  • Vitamin D3 directly supports a foundational nutrient need tied to immune function, calcium handling, and bone maintenance.
  • The cholecalciferol softgel uses a suitable form and lipid-based delivery.
  • The 5000 IU serving is concentrated and may fit people with a demonstrated need better than routine unsupervised use.

Cons

  • The duplicate vitamin D entries make the active disclosure ambiguous, and the amount may exceed some users' maintenance needs.
  • Raw-material sourcing and independent quality testing are not disclosed.
  • The high amount is not a balanced substitute for direct anti-inflammatory actives.
  • Vitamin D3 may improve fatigue or muscle weakness when low status is the underlying problem.
  • Its raw source and independent quality verification are not disclosed.

Warnings

  • The 5000 IU serving is concentrated and may fit people with a demonstrated need better than routine unsupervised use.
  • Daily use at this level may exceed routine maintenance needs and can raise calcium excessively in susceptible users.
  • The 5,000 IU daily amount is high for routine unsupervised use and may raise calcium or kidney-stone risk in susceptible users.
  • The amount exceeds the adult daily upper intake level used for routine unsupervised intake.

Nutrient quality

86 Highest impact

Cholecalciferol in a softgel is a well-absorbed form and suitable delivery format. The vitamin D3 amount is substantial when a high dose is needed.

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Ingredient transparency

70 High impact

The same vitamin D amount appears twice under overlapping names, creating uncertainty about the declaration. A complete oil carrier and inactive ingredient list was not supplied.

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Customer satisfaction

72 High impact

The available aggregate rating is strong for this category. No firsthand outcome details were supplied, so alignment with the intended use is uncertain.

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Value for money

96 Highest impact

The strong softgel format provides good quality despite the duplicate label entry. The product is highly competitive on serving value among concentrated vitamin D softgels.

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Report analysis

Goals

General Health
Impact
Highest effect
A+ Goal FitA- Strength of SupportC CoverageA Formula Quality
Vitamin D · 5000 IU

Vitamin D3 directly supports a foundational nutrient need tied to immune function, calcium handling, and bone maintenance. The cholecalciferol softgel uses a suitable form and lipid-based delivery.

The 5000 IU serving is concentrated and may fit people with a demonstrated need better than routine unsupervised use. Raw-material sourcing and independent quality testing are not disclosed.

Study evidence
Vitamin D Supportive 115 studies
Immunity
Impact
High effect
A Goal FitC+ Strength of SupportD+ CoverageA+ Formula Quality
Vitamin D · 5000 IU

Vitamin D3 directly supports immune-cell regulation and barrier function in a lipid-based softgel. The concentrated amount may suit people with a confirmed higher requirement.

The daily serving exceeds the adult upper intake level, so routine use is better guided by vitamin D status and professional advice. A single nutrient cannot cover antioxidant, mucosal, and acute-symptom pathways on its own.

Study evidence
Vitamin D Supportive 85 studies
Testosterone Support
Impact
High effect
B- Goal FitA- Strength of SupportD CoverageA+ Formula Quality
Vitamin D · 5000 IU

Vitamin D3 may support testosterone when vitamin D status is low, although human trials are mixed. The concentrated amount is clearly disclosed in a softgel suited to absorption.

Daily use at this level may exceed routine maintenance needs and can raise calcium excessively in susceptible users. Vitamin D and calcium status can help determine whether the amount is appropriate.

Study evidence
Vitamin D Supportive 56 studies
Anti-Aging
Impact
High effect
B- Goal FitB Strength of SupportD+ CoverageA Formula Quality
Vitamin D · 5000 IU

Vitamin D3 supports bone integrity, muscle function, and immune regulation, which are foundational to healthy aging. Its value is greatest when correcting or preventing inadequate vitamin D status rather than acting as a broad longevity intervention.

The cholecalciferol form and exact amount are clearly disclosed in a focused formula. The 5,000 IU daily amount is high for routine unsupervised use and may raise calcium or kidney-stone risk in susceptible users.

Study evidence
Vitamin D Supportive 50 studies
Anti-Inflammatory Support
Impact
High effect
B Goal FitB- Strength of SupportD- CoverageA- Formula Quality
Vitamin D · 5000 IU

Potent vitamin D3 may support healthier immune signaling when deficiency is present. The high amount is not a balanced substitute for direct anti-inflammatory actives.

It is better suited to monitored vitamin D repletion than broad inflammation support. Regular use at 5,000 IU warrants attention to total intake and vitamin D blood levels.

Study evidence
Vitamin D Supportive 101 studies
Energy
Impact
High effect
B- Goal FitB- Strength of SupportF CoverageA- Formula Quality
Vitamin D · 5000 IU

Vitamin D3 may improve fatigue or muscle weakness when low status is the underlying problem. The softgel provides clear cholecalciferol dosing in a format suited to a fat-soluble vitamin.

The amount exceeds the adult daily upper intake level used for routine unsupervised intake. Long-term use at this level can raise calcium exposure, so it is better matched to a documented need and monitored vitamin D status.

Study evidence
Vitamin D Supportive 32 studies

Ingredients

IngredientAmount per serving
Vitamin D (Cholecalciferol, Vitamin D3)
5000 IU
Gluten Free Adults 18–50 Dairy Free Sugar Free
Report overview
A Active Ingredient Quality & BioavailabilityC+ Dose, Safety & Label TransparencyA+ Value

The softgel provides vitamin D3 at the upper end of the preferred daily range with a lipid-based delivery format. Its raw source and independent quality verification are not disclosed. The concentrated dose delivers excellent vitamin D efficiency for users who need this intake level.

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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Vitamin D and risk of cause specific death: systematic review and meta-analysis of observational cohort and randomised intervention studies.
    Chowdhury R; Kunutsor S; Vitezova A; Oliver-Williams C; Chowdhury S; Kiefte-de-Jong JC; Khan H; Baena CP; Prabhakaran D; Hoshen MB; Feldman BS; Pan A; Johnson L; Crowe F; Hu FB; Franco OH · BMJ (Clinical research ed.) · 2014
    Meta-analysis95 studies pooledGeneral Health forVitamin D
  2. Vitamin D supplementation for prevention of mortality in adults.
    Bjelakovic G; Gluud LL; Nikolova D; Whitfield K; Wetterslev J; Simonetti RG; Bjelakovic M; Gluud C · The Cochrane database of systematic reviews · 2014
    Meta-analysis95,286 participants159 studies pooledGeneral Health forVitamin D
  3. The effects of vitamin D on all-cause mortality in different diseases: an evidence-map and umbrella review of 116 randomized controlled trials.
    Cao M; He C; Gong M; Wu S; He J · Frontiers in nutrition · 2023
    Meta-analysis149,865 participants116 studies pooledGeneral Health forVitamin D
  4. Vitamin D Status and Mortality: A Systematic Review of Observational Studies.
    Heath AK; Kim IY; Hodge AM; English DR; Muller DC · International journal of environmental research and public health · 2019
    Systematic review84 studies pooledGeneral Health forVitamin D
  5. Current opinion on the role of vitamin D supplementation in respiratory infections and asthma/COPD exacerbations: A need to establish publication guidelines for overcoming the unpublished data.
    Anitua E; Tierno R; Alkhraisat MH · Clinical nutrition (Edinburgh, Scotland) · 2022
    Meta-analysis50,554 participants65 studies pooledImmunity forVitamin D
  6. Association Between Vitamin D and Influenza: Meta-Analysis and Systematic Review of Randomized Controlled Trials.
    Zhu Z; Zhu X; Gu L; Zhan Y; Chen L; Li X · Frontiers in nutrition · 2022
    Meta-analysis4,859 participants10 studies pooledImmunity forVitamin D
  7. Vitamin D supplementation and hospitalization for infection in older adults: A post-hoc analysis of data from the Australian D-Health Trial.
    Pham H; Waterhouse M; Baxter C; Romero BD; McLeod DS; Armstrong BK; Ebeling PR; English DR; Hartel G; O'Connell RL; van der Pols JC; Venn AJ; Webb PM; Whiteman DC; Neale RE · The American journal of clinical nutrition · 2023
    Randomized trial21,315 participantsImmunity forVitamin D
  8. Effect of vitamin D status and vitamin D supplementation on immune function and prevention of acute respiratory tract infections in dark-skinned individuals: a systematic review and meta-analysis.
    Bournot AR; Darling AL; Givens ID; Lovegrove JA; Lanham-New SA; Hart KH · Public health nutrition · 2024
    Meta-analysis36,707 participants18 studies pooledImmunity forVitamin D
  9. Effect of moderate or high versus low dose daily vitamin D on COVID-19 incidence: A double-blind, parallel-group randomized clinical trial.
    Meltzer DO; Moy JN; Schram AW; Tate A; Hyman MJ; Cursio JF; Vokes T; Yeo KJ; Prochaska M; Jacobs JJ; Solway J · Clinical nutrition (Edinburgh, Scotland) · 2026
    Randomized trial955 participantsImmunity forVitamin D
  10. Effect of Vitamin D Supplementation on Fatigue in Multiple Sclerosis: A Systematic Review and Meta-Analysis.
    López-Muñoz P; Torres-Costoso AI; Fernández-Rodríguez R; Guzmán-Pavón MJ; de Arenas-Arroyo SN; Basco-López JÁ; Reina-Gutiérrez S · Nutrients · 2023
    Meta-analysis345 participants5 studies pooledEnergy forVitamin D
  11. Vitamin D for the management of multiple sclerosis.
    Jagannath VA; Filippini G; Di Pietrantonj C; Asokan GV; Robak EW; Whamond L; Robinson SA · The Cochrane database of systematic reviews · 2018
    Meta-analysis933 participants12 studies pooledEnergy forVitamin D
  12. Vitamin D levels and menopause-related symptoms.
    LeBlanc ES; Desai M; Perrin N; Wactawski-Wende J; Manson JE; Cauley JA; Michael YL; Tang J; Womack C; Song Y; Johnson KC; O'Sullivan MJ; Woods N; Stefanick ML · Menopause (New York, N.Y.) · 2015
    Cross-sectional study530 participantsEnergy forVitamin D
  13. Fatigue and Vitamin D Status in Frail Elderly with and without Cancer, and Healthy Controls of Different Ages: Results from the IMAGE Study.
    Dahlén E; Hedman C; Mily A; Alisjahbana A; Spulber G; Holmström-Edstedt J; Bergman P; Buggert M; Björkhem-Bergman L · Gerontology · 2025
    Cohort study273 participantsEnergy forVitamin D
  14. Role of vitamin D as adjuvant therapy on multiple sclerosis: an updated systematic review and meta-analysis of randomized controlled trials.
    Serag I; Abouzid M; Alsaadany KR; Hendawy M; Ali HT; Yaseen Y; Moawad MHED · European journal of medical research · 2025
    Meta-analysis1,903 participants21 studies pooledEnergy forVitamin D
  15. Joint association of serum 25-hydroxyvitamin D concentration and body mass index on the acceleration of clinical biomarker-based biological aging.
    Pan Z; Zeng J; Chen Z; Chen S; Yang J; Li H; Wang S; Wang J; Li N; Gong Y; Liu M; Li C · The journals of gerontology. Series A, Biological sciences and medical sciences · 2026
    Cohort study389,217 participantsAnti-Aging forVitamin D
  16. Serum 25-Hydroxyvitamin D Levels as an Aging Marker: Strong Associations With Age and All-Cause Mortality Independent From Telomere Length, Epigenetic Age Acceleration, and 8-Isoprostane Levels.
    Schöttker B; Hagen L; Zhang Y; Gào X; Holleczek B; Gao X; Brenner H · The journals of gerontology. Series A, Biological sciences and medical sciences · 2019
    Cohort study9,940 participantsAnti-Aging forVitamin D
  17. Sex-specific associations of serum 25-hydroxyvitamin D concentrations with incident sarcopenia in older adults: A 2-year follow-up study.
    Song S; Lim JY; Kim M; Won CW; Park HY · The journal of nutrition, health & aging · 2025
    Cohort study1,292 participantsAnti-Aging forVitamin D
  18. Vitamin D deficit is associated with accelerated brain aging in the general population.
    Terock J; Bonk S; Frenzel S; Wittfeld K; Garvert L; Hosten N; Nauck M; Völzke H; Van der Auwera S; Grabe HJ · Psychiatry research. Neuroimaging · 2022
    Cross-sectional study1,865 participantsAnti-Aging forVitamin D
  19. Vitamin D intake is associated with dementia risk in the Washington Heights-Inwood Columbia Aging Project (WHICAP).
    Zhao C; Tsapanou A; Manly J; Schupf N; Brickman AM; Gu Y · Alzheimer's & dementia : the journal of the Alzheimer's Association · 2021
    Cohort study1,759 participantsAnti-Aging forVitamin D
  20. Vitamin D deficiency and C-reactive protein: a bidirectional Mendelian randomization study.
    Zhou A; Hyppönen E · International journal of epidemiology · 2023
    Observational study294,970 participantsAnti-Inflammatory Support forVitamin D
  21. Vitamin D in Children With Inflammatory Bowel Disease: A Randomized Controlled Clinical Trial.
    El Amrousy D; El Ashry H; Hodeib H; Hassan S · Journal of clinical gastroenterology · 2021
    Randomized trial120 participantsAnti-Inflammatory Support forVitamin D
  22. Vitamin D supplementation reduces infection rate and promotes wound healing in patients with diabetic foot ulcers.
    Gao YQ; Gao YH; Xing JH · World journal of diabetes · 2025
    Randomized trial120 participantsAnti-Inflammatory Support forVitamin D
  23. Associations of C-reactive Protein with 25-hydroxyvitamin D in 24 Specific Diseases: A Cross-sectional Study from NHANES.
    Yang F; Sun M; Sun C; Li J; Yang X; Bi C; Wang M; Pu L; Wang J; Wang C; Xie M; Yao Y; Jin L · Scientific reports · 2020
    Cross-sectional study9,809 participantsAnti-Inflammatory Support forVitamin D
  24. Combined effects of vitamin D deficiency and systemic inflammation on all-cause mortality and cause-specific mortality in older adults.
    Zhang C; Cui J; Li S; Shen J; Luo X; Yao Y; Shi H · BMC geriatrics · 2024
    Cohort study3,072 participantsAnti-Inflammatory Support forVitamin D
  25. Vitamin D Supplementation in Adolescents and Young Adults With Juvenile Systemic Lupus Erythematosus for Improvement in Disease Activity and Fatigue Scores: A Randomized, Double-Blind, Placebo-Controlled Trial.
    Lima GL; Paupitz J; Aikawa NE; Takayama L; Bonfa E; Pereira RM · Arthritis care & research · 2016
    Randomized trial40 participantsEnergy forVitamin D
  26. Vitamin D in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome After COVID-19 or Vaccination: A Randomized Controlled Trial.
    Kodama S; Nakata M; Konishi N; Yoshino M; Fujisawa A; Naganuma M; Kobayashi Y; Hirai Y; Kitagawa A; Miyokawa M; Mishima R; Teramukai S; Fukushima M · Nutrients · 2026
    Randomized trial91 participantsEnergy forVitamin D
  27. The effects of vitamin D supplementation on disease activity and fatigue in Libyan rheumatoid arthritis patients.
    Elfituri S · Reumatologia · 2024
    Randomized trial68 participantsEnergy forVitamin D
  28. The effect of home-based aerobic training and vitamin D supplementation on fatigue and quality of life in patients with multiple sclerosis during COVID-19 outbreak.
    Bahmani E; Hoseini R; Amiri E · Science & sports · 2022
    Randomized trial40 participantsEnergy forVitamin D
  29. Effect of vitamin D on gastrointestinal symptoms and health-related quality of life in irritable bowel syndrome patients: a randomized double-blind clinical trial.
    Abbasnezhad A; Amani R; Hajiani E; Alavinejad P; Cheraghian B; Ghadiri A · Neurogastroenterology and motility · 2018
    Randomized trial90 participantsGeneral Health forVitamin D
  30. The impact of vitamin D administration on mortality in COVID-19 patients: a systematic review and meta-analysis of randomized controlled trials.
    Kow CS; Ramachandram DS; Hasan SS; Wong Z; Thiruchelvam K · Inflammopharmacology · 2024
    Meta-analysis2,495 participants19 studies pooledGeneral Health forVitamin D
  31. Meta-analysis of long-term vitamin D supplementation on overall mortality.
    Zheng Y; Zhu J; Zhou M; Cui L; Yao W; Liu Y · PloS one · 2014
    Meta-analysis42 studies pooledGeneral Health forVitamin D
  32. Vitamin D supplementation to prevent acute respiratory infections: individual participant data meta-analysis.
    Martineau AR; Jolliffe DA; Greenberg L; Aloia JF; Bergman P; Dubnov-Raz G; Esposito S; Ganmaa D; Ginde AA; Goodall EC; Grant CC; Janssens W; Jensen ME; Kerley CP; Laaksi I; Manaseki-Holland S; Mauger D; Murdoch DR; Neale R; Rees JR; Simpson S; Stelmach I; Trilok Kumar G; Urashima M; Camargo CA; Griffiths CJ; Hooper RL · Health technology assessment (Winchester, England) · 2020
    Meta-analysis11,321 participants25 studies pooledImmunity forVitamin D
  33. Vitamin D3 and deconvoluting a rash.
    Ernst MK; Evans ST; Techner JM; Rothbaum RM; Christensen LF; Onay UV; Biyashev D; Demczuk MM; Nguyen CV; Honda KS; McCormick TS; Tsoi LC; Gudjonsson JE; Cooper KD; Lu KQ · JCI insight · 2023
    Randomized trial28 participantsImmunity forVitamin D
  34. Effect of vitamin D3 supplementation on cellular immunity and inflammatory markers in COVID-19 patients admitted to the ICU.
    Bychinin MV; Klypa TV; Mandel IA; Yusubalieva GM; Baklaushev VP; Kolyshkina NA; Troitsky AV · Scientific reports · 2022
    Randomized trial110 participantsImmunity forVitamin D
  35. Effect of Two Different Doses of Vitamin D Supplementation on Metabolic Profiles of Insulin-Resistant Patients with Polycystic Ovary Syndrome.
    Jamilian M; Foroozanfard F; Rahmani E; Talebi M; Bahmani F; Asemi Z · Nutrients · 2018
    Randomized trial90 participantsTestosterone Support forVitamin D
  36. Androgens and hirsutism score of overweight women with polycystic ovary syndrome improved after vitamin D treatment: A randomized placebo controlled clinical trial.
    Al-Bayyari N; Al-Domi H; Zayed F; Hailat R; Eaton A · Clinical nutrition (Edinburgh, Scotland) · 2021
    Randomized trial60 participantsTestosterone Support forVitamin D
  37. Association between plasma 25-OH vitamin D and testosterone levels in men.
    Nimptsch K; Platz EA; Willett WC; Giovannucci E · Clinical endocrinology · 2012
    Case-control study1,362 participantsTestosterone Support forVitamin D
  38. Causal Link Between Vitamin D and Total Testosterone in Men: A Mendelian Randomization Analysis.
    Chen C; Zhai H; Cheng J; Weng P; Chen Y; Li Q; Wang C; Xia F; Wang N; Lu Y · The Journal of clinical endocrinology and metabolism · 2020
    Other4,254 participantsTestosterone Support forVitamin D
  39. Associations of vitamin D status and vitamin D-related polymorphisms with sex hormones in older men.
    Rafiq R; van Schoor NM; Sohl E; Zillikens MC; Oosterwerff MM; Schaap L; Lips P; de Jongh RT · The Journal of steroid biochemistry and molecular biology · 2017
    Cohort study643 participantsTestosterone Support forVitamin D