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Chelated Magnesium 250 mg

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4.8
★ ★ ★ ★ ★
(5597 ratings)
Magnesium 250 mg
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Score80
A good-value mixed-form magnesium, with useful dosing but limited clarity about its chelated and oxide shares.
How scoring works
Quantity:180 Tablet(s) • (180 servings)
Goals:
Stress Relief
General Health
Energy
Heart Health
Cardiovascular Support

Score 80

A good-value mixed-form magnesium, with useful dosing but limited clarity about its chelated and oxide shares.
How scoring works
$20.49($0.11 per serving)
Vitacost
$ 20.49
Pure Formulas
$ 20.49
Vitacost
$ 20.49
iHerb
$ 20.49
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Analysis

The moderate magnesium amount and large tablet supply support straightforward daily use. An amino acid chelate gives the blend better potential than an oxide-only formula.

Magnesium oxide still lowers the likely absorption quality and may increase bowel effects. Repeating the same amount for both forms does not explain how much elemental magnesium each source contributes.

The larger bottle offers favorable practical value. Users prioritizing form quality may still prefer a product made entirely with citrate or bisglycinate.

Who is it for
  • Long-term tablet users
  • Adults wanting moderate daily magnesium
  • Value-focused shoppers
Best for
  • Routine magnesium intake
  • Muscle and nerve support
  • Longer-supply purchasing

Pros

  • Contains an amino acid chelate
  • Moderate magnesium amount
  • Favorable value from the larger supply

Cons

  • Contains low-absorption oxide
  • Form contributions are not separated
  • No complementary nutrients

Warnings

  • Magnesium oxide may cause loose stools or cramping
  • A full tablet may be difficult for people sensitive to magnesium
  • Impaired kidney function can increase magnesium accumulation risk

Nutrient quality

78 High impact

An amino acid chelate and oxide blend provides the main quality signal, while a moderate magnesium amount shapes likely usefulness. Absorption, tolerability, and the formula's focus determine the main trade-off.

Ingredient transparency

66 High impact

Active amounts are only partly clear, and no proprietary blend hides the total formula. Specific ingredient names make the core actives reasonably easy to assess.

Customer satisfaction

91 Highest impact

The high average rating is supported by substantial review volume. No specific review comments are supplied, so repeated complaints and purpose alignment cannot be confirmed directly.

Value for money

94 Highest impact

Value is favorable for the form quality and disclosed amount. The focused formula avoids paying for token extras, while category competitiveness depends on absorption quality.

Report analysis

Goals

Stress Relief
Impact
High effect
B+ Goal FitB+ Strength of SupportC- CoverageA Formula Quality
Magnesium · 250 mg

A meaningful magnesium amount supports normal nervous-system regulation and may help when low magnesium status worsens stress sensitivity. Its benefit is most likely for users with inadequate intake rather than as a rapid calming agent.

The amino-acid chelate may absorb reasonably, but magnesium oxide lowers systemic availability. The oxide component may also cause loose stools in sensitive users. The single-mineral focus provides useful depth but does not address neurotransmitters or the stress-response axis directly.

Study evidence
Magnesium Supportive 13 studies
Impact
High effect
A Goal FitB- Strength of SupportD CoverageA- Formula Quality
Magnesium · 250 mg

Magnesium directly supports energy metabolism, muscle function, and nervous-system health. The clearly stated elemental amount provides useful daily coverage.

An amino acid chelate may improve uptake, but the accompanying oxide prevents a consistently well-absorbed profile. The focused single-mineral design avoids unrelated additions.

Study evidence
Magnesium Supportive 114 studies
Energy
Impact
High effect
B+ Goal FitB Strength of SupportC- CoverageA- Formula Quality
Magnesium · 250 mg

Magnesium directly supports ATP-dependent metabolism at a practical daily amount. The focused tablet may help when inadequate intake contributes to tiredness.

An amino acid chelate is included, but magnesium oxide lowers confidence in absorption. The formula does not address alertness, mitochondrial cofactors beyond magnesium, or stress resilience.

Study evidence
Magnesium Supportive 4 studies
Impact
High effect
B Goal FitB Strength of SupportD+ CoverageA Formula Quality
Magnesium · 250 mg

A clearly disclosed 250 mg magnesium amount provides focused support for vascular tone and normal heart rhythm. The simple single-mineral approach gives one cardiovascular pathway meaningful depth.

An amino acid chelate improves the source blend, but included magnesium oxide lowers absorption quality. No potassium, CoQ10, omega-3, nitric oxide, or homocysteine pathway broadens the formula.

Study evidence
Magnesium Supportive 158 studies
Cardiovascular Support
Impact
High effect
B+ Goal FitB Strength of SupportD CoverageA+ Formula Quality
Magnesium · 250 mg

Magnesium may support vascular relaxation and stable cardiac electrical activity when intake is low. The elemental amount is useful for daily supplementation.

An amino-acid chelate may improve absorption, but the accompanying oxide prevents a premium form profile. The focused formula provides good depth in one pathway without broader lipid or endothelial support.

Study evidence
Magnesium Supportive 123 studies
Bone Health
Impact
Moderate effect
C+ Goal FitC+ Strength of SupportF CoverageB Formula Quality
Magnesium · 250 mg

A 250 mg magnesium serving supports mineralization and normal calcium regulation. The amino acid chelate may improve uptake, while the accompanying oxide lowers the overall form quality.

Coverage remains limited to one mineral pathway because calcium, vitamins D and K, and matrix-support ingredients are absent. The simple formula avoids distractions and provides useful depth for magnesium alone.

Study evidence
Magnesium Supportive 48 studies

Ingredients

IngredientAmount per serving
Magnesium (Magnesium Amino Acid Chelate, Magnesium Oxide)
250 mg
Gluten Free Adults 18–50 Vegan Kosher Dairy Free Sugar Free Vegetarian
Report overview
D- Active Ingredient Quality & BioavailabilityA Dose, Safety & Label TransparencyB+ Value

An amino acid chelate may improve absorption, but the accompanying oxide prevents a fully premium profile. 250 mg of elemental magnesium is clearly disclosed and falls in the standard supplemental range; the clean single-mineral design is simple but adds no uptake or bone-health cofactor. The low serving cost provides good value despite the mixed or moderate-quality form.

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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Long-term outcome after intravenous magnesium sulphate in suspected acute myocardial infarction: the second Leicester Intravenous Magnesium Intervention Trial (LIMIT-2).
    Woods KL; Fletcher S · Lancet (London, England) · 1994
    Randomized trial2,316 participantsGeneral Health forMagnesium
  2. Hospital-Acquired Dysmagnesemia and In-Hospital Mortality.
    Cheungpasitporn W; Thongprayoon C; Chewcharat A; Petnak T; Mao MA; Davis PW; Bathini T; Vallabhajosyula S; Qureshi F; Erickson SB · Medical sciences (Basel, Switzerland) · 2024
    Cohort study26,020 participantsGeneral Health forMagnesium
  3. A Randomized Double-blind Placebo-controlled Trial on the Effect of Magnesium Oxide in Patients With Chronic Constipation.
    Mori S; Tomita T; Fujimura K; Asano H; Ogawa T; Yamasaki T; Kondo T; Kono T; Tozawa K; Oshima T; Fukui H; Kimura T; Watari J; Miwa H · Journal of neurogastroenterology and motility · 2022
    Randomized trial34 participantsDigestive Health forMagnesium
  4. Diagnosis of magnesium-induced diarrhea.
    Fine KD; Santa Ana CA; Fordtran JS · The New England journal of medicine · 1991
    Clinical trial19 participantsDigestive Health forMagnesium
  5. Association between Serum Magnesium and Fractures: A Systematic Review and Meta-Analysis of Observational Studies.
    Dominguez LJ; Veronese N; Ciriminna S; Pérez-Albela JL; Vásquez-López VF; Rodas-Regalado S; Di Bella G; Parisi A; Tagliaferri F; Barbagallo M · Nutrients · 2023
    Meta-analysis119,755 participants4 studies pooledBone Health forMagnesium
  6. Bioabsorbable Magnesium-Based Materials Potential and Safety in Bone Surgery: A Systematic Review.
    Hung CH; Kwok YC; Yip J; Wong HH; Leung YY · Craniomaxillofacial trauma & reconstruction · 2025
    Systematic review386 participants8 studies pooledBone Health forMagnesium
  7. Vascularized bone grafting fixed by biodegradable magnesium screw for treating osteonecrosis of the femoral head.
    Zhao D; Huang S; Lu F; Wang B; Yang L; Qin L; Yang K; Li Y; Li W; Wang W; Tian S; Zhang X; Gao W; Wang Z; Zhang Y; Xie X; Wang J; Li J · Biomaterials · 2016
    Randomized trial48 participantsBone Health forMagnesium
  8. An update on magnesium and bone health.
    Rondanelli M; Faliva MA; Tartara A; Gasparri C; Perna S; Infantino V; Riva A; Petrangolini G; Peroni G · Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2022
    Narrative reviewBone Health forMagnesium
  9. Sex-specific differences in the association of magnesium intake with femoral neck bone mineral density among older adults.
    Wang B; Tan X; Yao X; Zhu Z · Endocrine connections · 2025
    Cross-sectional study1,343 participantsBone Health forMagnesium
  10. Circulating and dietary magnesium and risk of cardiovascular disease: a systematic review and meta-analysis of prospective studies.
    Del Gobbo LC; Imamura F; Wu JH; de Oliveira Otto MC; Chiuve SE; Mozaffarian D · The American journal of clinical nutrition · 2013
    Meta-analysis313,041 participants16 studies pooledCardiovascular Support forMagnesium
  11. Magnesium and the risk of cardiovascular events: a meta-analysis of prospective cohort studies.
    Qu X; Jin F; Hao Y; Li H; Tang T; Wang H; Yan W; Dai K · PloS one · 2013
    Meta-analysis532,979 participants19 studies pooledCardiovascular Support forMagnesium
  12. Quantitative Association Between Serum/Dietary Magnesium and Cardiovascular Disease/Coronary Heart Disease Risk: A Dose-Response Meta-analysis of Prospective Cohort Studies.
    Zhao L; Hu M; Yang L; Xu H; Song W; Qian Y; Zhao M · Journal of cardiovascular pharmacology · 2020
    Meta-analysis544,581 participants18 studies pooledCardiovascular Support Heart Health forMagnesium
  13. Comparative Efficacy of Nutraceuticals on Endothelial Function: A Systematic Review and Network Meta-Analysis.
    Norouzzadeh M; Rashedi MH; Mahdavi-Mazdeh G; Kosari A; Shahinfar H · Current atherosclerosis reports · 2026
    Meta-analysisCardiovascular Support Heart Health forMagnesium
  14. Serum magnesium, mortality, and cardiovascular disease in chronic kidney disease and end-stage renal disease patients: a systematic review and meta-analysis.
    Xiong J; He T; Wang M; Nie L; Zhang Y; Wang Y; Huang Y; Feng B; Zhang J; Zhao J · Journal of nephrology · 2020
    Meta-analysis200,934 participants20 studies pooledCardiovascular Support forMagnesium
  15. Efficacy of oral magnesium therapy in the treatment of chronic constipation in spastic cerebral palsy children: a randomized controlled trial.
    Hassanein SMA; Deifallah SM; Bastawy HA · World journal of pediatrics : WJP · 2021
    Randomized trial100 participantsDigestive Health forMagnesium
  16. Ca:Mg ratio, medium-chain fatty acids, and the gut microbiome.
    Fan L; Zhu X; Sun S; Yu C; Huang X; Ness R; Dugan LL; Shu L; Seidner DL; Murff HJ; Fodor AA; Azcarate-Peril MA; Shrubsole MJ; Dai Q · Clinical nutrition (Edinburgh, Scotland) · 2022
    Randomized trial240 participantsDigestive Health forMagnesium
  17. The Magnesium-Rich Formula for Functional Constipation in Infants: a Randomized Comparator-Controlled Study.
    Benninga MA; MENA Infant Constipation Study Group; Vandenplas Y · Pediatric gastroenterology, hepatology & nutrition · 2022
    Randomized trial286 participantsDigestive Health forMagnesium
  18. Magnesium treatment increases gut microbiome synthesizing vitamin D and inhibiting colorectal cancer: results from a double-blind precision-based randomized placebo-controlled trial.
    Sun E; Zhu X; Ness RM; Murff HJ; Sun S; Yu C; Fan L; Azcarate-Peril MA; Shrubsole MJ; Dai Q · The American journal of clinical nutrition · 2025
    Randomized trial240 participantsDigestive Health forMagnesium
  19. Magnesium-L-threonate improves sleep quality and daytime functioning in adults with self-reported sleep problems: A randomized controlled trial.
    Hausenblas HA; Lynch T; Hooper S; Shrestha A; Rosendale D; Gu J · Sleep medicine: X · 2025
    Randomized trial80 participantsEnergy forMagnesium
  20. Total magnesium intake and risk of frailty in older women.
    Struijk EA; Fung TT; Bischoff-Ferrari HA; Willett WC; Lopez-Garcia E · Journal of cachexia, sarcopenia and muscle · 2024
    Cohort study81,524 participantsEnergy forMagnesium
  21. Red blood cell magnesium and chronic fatigue syndrome.
    Cox IM; Campbell MJ; Dowson D · Lancet (London, England) · 1991
    Randomized trial32 participantsEnergy forMagnesium
  22. Exercise, magnesium and immune function.
    Laires MJ; Monteiro C · Magnesium research · 2008
    Narrative reviewEnergy forMagnesium
  23. Perioperative systemic magnesium to minimize postoperative pain: a meta-analysis of randomized controlled trials.
    De Oliveira GS; Castro-Alves LJ; Khan JH; McCarthy RJ · Anesthesiology · 2013
    Meta-analysis1,257 participants20 studies pooledGeneral Health forMagnesium
  24. Association of magnesium sulfate use with mortality in critically ill patients with sepsis: a retrospective propensity score-matched cohort study.
    Gu WJ; Duan XJ; Liu XZ; Cen Y; Tao LY; Lyu J; Yin HY · British journal of anaesthesia · 2023
    Cohort study10,999 participantsGeneral Health forMagnesium
  25. Hypomagnesemia and Mortality in Incident Hemodialysis Patients.
    Li L; Streja E; Rhee CM; Mehrotra R; Soohoo M; Brunelli SM; Kovesdy CP; Kalantar-Zadeh K · American journal of kidney diseases : the official journal of the National Kidney Foundation · 2016
    Cohort study9,359 participantsGeneral Health forMagnesium
  26. The effects of magnesium supplementation on abnormal uterine bleeding, alopecia, quality of life, and acne in women with polycystic ovary syndrome: a randomized clinical trial.
    Jaripur M; Ghasemi-Tehrani H; Askari G; Gholizadeh-Moghaddam M; Clark CCT; Rouhani MH · Reproductive biology and endocrinology : RB&E · 2022
    Randomized trial64 participantsGeneral Health forMagnesium
  27. Effects of magnesium supplementation on improving hyperglycemia, hypercholesterolemia, and hypertension in type 2 diabetes: A pooled analysis of 24 randomized controlled trials.
    Xu L; Li X; Wang X; Xu M · Frontiers in nutrition · 2023
    Meta-analysis1,325 participants24 studies pooledHeart Health forMagnesium
  28. The effect of lowering blood pressure by magnesium supplementation in diabetic hypertensive adults with low serum magnesium levels: a randomized, double-blind, placebo-controlled clinical trial.
    Guerrero-Romero F; Rodríguez-Morán M · Journal of human hypertension · 2009
    Randomized trial82 participantsHeart Health forMagnesium
  29. Positive effects of magnesium supplementation in metabolic syndrome.
    Kisters S; Kisters K; Werner T; Vormann J; Tokmak F; Westhoff T; Gröber U; Predel HG; Reuter H · International journal of clinical pharmacology and therapeutics · 2024
    Randomized trial54 participantsHeart Health forMagnesium
  30. Role of magnesium supplementation in the treatment of depression: A randomized clinical trial.
    Tarleton EK; Littenberg B; MacLean CD; Kennedy AG; Daley C · PloS one · 2017
    Randomized trial126 participantsStress Relief forMagnesium
  31. Effects of Intravenous Esketamine or Magnesium Sulfate on Early Postoperative Negative Emotions and Pain in Patients Undergoing Endoscopic Sinus Surgery: A Randomized Controlled Trial.
    Wang L; Zhou J; Liu Q; Qian K; Wang L; Xie C · Therapeutics and clinical risk management · 2026
    Randomized trial137 participantsStress Relief forMagnesium
  32. Effect of short-term magnesium supplementation on anxiety, depression and sleep quality in patients after open-heart surgery.
    Saba S; Faizi F; Sepandi M; Nehrir B · Magnesium research · 2022
    Non-randomized trial60 participantsStress Relief forMagnesium
  33. Effects of dry needling compared to magnesium infiltration in trigger points for patients with myofascial pain syndrome: a randomized controlled study in Tunisia.
    Dhouibi J; Moncer R; Kalbousi N; Gaddour M; Laayouni S; Ouanes W; Kacem B; Jemni S · Korean journal of family medicine · 2026
    Randomized trial45 participantsStress Relief forMagnesium
  34. Effect of magnesium and vitamin B6 supplementation on mental health and quality of life in stressed healthy adults: Post-hoc analysis of a randomised controlled trial.
    Noah L; Dye L; Bois De Fer B; Mazur A; Pickering G; Pouteau E · Stress and health : journal of the International Society for the Investigation of Stress · 2021
    Randomized trialStress Relief forMagnesium
  35. Magnesium and anabolic hormones in older men.
    Maggio M; Ceda GP; Lauretani F; Cattabiani C; Avantaggiato E; Morganti S; Ablondi F; Bandinelli S; Dominguez LJ; Barbagallo M; Paolisso G; Semba RD; Ferrucci L · International journal of andrology · 2012
    Cohort study399 participantsTestosterone Support forMagnesium
  36. Analysis of the relationship between the blood concentration of several metals, macro- and micronutrients and endocrine disorders associated with male aging.
    Rotter I; Kosik-Bogacka DI; Dołęgowska B; Safranow K; Kuczyńska M; Laszczyńska M · Environmental geochemistry and health · 2017
    Cross-sectional study313 participantsTestosterone Support forMagnesium
  37. Effect of magnesium supplementation in improving hyperandrogenism, hirsutism, and sleep quality in women with polycystic ovary syndrome: A randomized, placebo-controlled clinical trial.
    Gholizadeh-Moghaddam M; Ghasemi-Tehrani H; Askari G; Jaripur M; Clark CCT; Rouhani MH · Health science reports · 2024
    Randomized trial64 participantsTestosterone Support forMagnesium
  38. The effects of trace element supplementation on glycolipid metabolism in PCOS: a systematic review and meta-analysis.
    Yang L; Gao Y; Zhao W; Qi Y; Duo X; Wang H · Frontiers in nutrition · 2025
    Meta-analysis1,600 participants25 studies pooledTestosterone Support forMagnesium
  39. Effects of magnesium supplementation on testosterone levels of athletes and sedentary subjects at rest and after exhaustion.
    Cinar V; Polat Y; Baltaci AK; Mogulkoc R · Biological trace element research · 2011
    Non-randomized trial20 participantsTestosterone Support forMagnesium