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Chelated Magnesium 250 mg

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4.8
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(5576 ratings)
Magnesium 250 mg
Product Image
Score77
A cheap mixed chelate-and-oxide tablet offers basic magnesium support, but ambiguous form quantities and oxide content limit confidence.
How scoring works
Quantity:240 Tablet(s) • (240 servings)
Goals:
General Health
Heart Health
Energy
Cardiovascular Support

Score 77

A cheap mixed chelate-and-oxide tablet offers basic magnesium support, but ambiguous form quantities and oxide content limit confidence.
How scoring works

Also available as

2 options
180 servings Magnesium 250 mg • 180 Tablet(s) • 180 servings $20.49 ($0.11 per serving) 90 servings Magnesium 250 mg • 90 Tablet(s) • 90 servings $14.99 ($0.16 per serving)
$22.49($0.09 per serving)
Vitacost
$ 22.49
iHerb
$ 22.49
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Analysis

The product is presented as providing 250 mg of chelated magnesium, while the supplied ingredient data repeat 250 mg for amino acid chelate, oxide, and rice protein entries. Users should confirm whether 250 mg is the total elemental amount rather than adding those entries together.

An amino acid chelate can support systemic absorption, but the oxide portion is less efficiently absorbed and more likely to affect the bowel. A one-tablet serving and very low cost are practical strengths.

It fits budget-focused users who accept a mixed-form product. People seeking a reliably gentle or fully chelated magnesium should choose a formula with an explicit form ratio.

Who is it for
  • Budget-focused adults
  • People comfortable with mixed magnesium forms
  • Users wanting one-tablet convenience
Best for
  • Low-cost general magnesium use
  • Mixed-form supplementation
  • Large-count convenience

Pros

  • Includes an amino acid chelate
  • One-tablet serving
  • Large bottle supply
  • Very low serving cost

Cons

  • Contains poorly absorbed magnesium oxide
  • Form ratios are not clear
  • Repeated 250 mg entries create dose ambiguity
  • May be less gentle than a pure chelate

Warnings

  • Confirm the current label rather than adding the repeated 250 mg form entries together.
  • The oxide-containing serving of supplemental magnesium may cause loose stools, cramping, or nausea; a smaller divided amount may be easier to tolerate.
  • Magnesium can reduce absorption of tetracycline or quinolone antibiotics; follow the prescriber or pharmacist’s spacing instructions.
  • Magnesium can interfere with levothyroxine absorption and should be separated according to medication guidance.

Nutrient quality

78 High impact

An amino acid chelate is paired with poorly absorbed magnesium oxide, creating mixed form quality. The elemental amount is meaningful for daily supplementation, while the moderate total is reasonable, although the oxide portion may loosen stools.

Ingredient transparency

71 High impact

Multiple magnesium source lines share the same amount, making elemental and compound contributions ambiguous. Serving totals are apparent, but full directions and inactive ingredients are not supplied.

Customer satisfaction

72 High impact

The supplied average rating is exceptionally strong. The very large rating base makes the average unusually stable, while complaint and firsthand experience details are unavailable.

Value for money

91 Highest impact

Formula quality supports the asking position well. The serving value is highly competitive within the category.

Report analysis

Goals

General Health
Stress Resilience
General Health
Impact
High effect
A Goal FitB- Strength of SupportC CoverageA- Formula Quality
Magnesium · 250 mg

A substantial magnesium amount directly supports a foundational mineral need involved in hundreds of metabolic reactions. The formula is focused, fully quantified, and includes an amino acid chelate component.

Magnesium oxide lowers expected absorption quality and may be more likely to cause loose stools than gentler forms. It can support general magnesium intake, but the mixed-form label prevents judging how much comes from the better chelated source.

Study evidence
Magnesium Supportive 114 studies
Heart Health
Healthy Blood Pressure
Heart Health
Impact
High effect
A- Goal FitB Strength of SupportC- CoverageA Formula Quality
Magnesium · 250 mg

Magnesium supports normal vascular tone, cardiac rhythm, and cellular energy at a substantial daily amount. Its cardiovascular role is well established, especially when intake is inadequate.

Amino acid chelation improves part of the formula, while magnesium oxide lowers expected absorption. The focused tablet supports one mineral pathway without broader lipid, vascular, or cardiac-energy coverage.

Study evidence
Magnesium Supportive 158 studies
Energy
Energy
Impact
High effect
A- Goal FitB+ Strength of SupportC- CoverageA- Formula Quality
Magnesium · 250 mg

A substantial magnesium amount supports ATP-dependent enzymes and may help when low intake contributes to fatigue. The blend includes an amino-acid chelate but also relies on poorly absorbed magnesium oxide.

Its single-mineral focus provides strong depth without alertness or stress-resilience coverage. The oxide component may also cause loose stools or stomach discomfort in sensitive users.

Study evidence
Magnesium Supportive 4 studies
Cardiovascular Support
Cardiovascular Support
Impact
High effect
B- Goal FitB- Strength of SupportD CoverageC+ Formula Quality
Magnesium · 250 mg

The disclosed magnesium amount supports vascular tone and normal heart rhythm, but absorption quality is mixed. Magnesium oxide weakens the systemic value of the accompanying amino acid chelate.

The elemental amount is practical for routine use and the cardiovascular purpose is focused. Multiple magnesium sources are not clearly justified, and the oxide component may cause loose stools in sensitive users.

Study evidence
Magnesium Supportive 123 studies
Stress Relief
Stress Relief
Impact
Moderate effect
C+ Goal FitC+ Strength of SupportD- CoverageC+ Formula Quality
Magnesium · 250 mg

The magnesium amount is well aligned for foundational nervous-system support, but the blend includes poorly absorbed magnesium oxide. An amino acid chelate may improve part of the delivery, yet the label does not show how much each form contributes.

The single-mineral purpose is clear and avoids unrelated active ingredients. Magnesium oxide can cause loose stools or abdominal discomfort in sensitive users, especially at the full serving.

Study evidence
Magnesium Supportive 13 studies
Testosterone Support
Testosterone Support
Impact
Moderate effect
C- Goal FitB- Strength of SupportD- CoverageB Formula Quality
Magnesium · 250 mg

Magnesium provides a legitimate but narrow nutritional contribution to healthy hormone function. The product does not cover the broader pathways expected from a testosterone-support formula.

The elemental amount is useful and inexpensive, but magnesium oxide lowers absorption confidence. The mixed form may also be more likely to cause loose stools in sensitive users.

Study evidence
Magnesium Disputed 5 studies

Ingredients

IngredientAmount per serving
Magnesium (Magnesium Amino Acid Chelate, Magnesium Oxide, Rice Protein)
 250 mg
Gluten Free Adults 18–50 Vegan Kosher Dairy Free Sugar Free Vegetarian
Report overview
Magnesium (Magnesium Amino Acid Chelate, Magnesium Oxide, Rice Protein) · 250 mg OverallScore60
F Active Ingredient Quality & BioavailabilityA Dose, Safety & Label TransparencyD+ Value

Amino acid chelate is paired with poorly absorbed magnesium oxide, creating mixed absorption quality despite a well-aligned elemental amount. No patented chelation standard or uptake co-factor is disclosed. The very low serving cost partly offsets the oxide component, which may also increase the chance of loose stools.

View ingredientView products
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Magnesium Bisglycinate Chelate

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<p>Magnesium glycinate is a well-absorbed form that is often gentle on digestion. Its stated magnesium form and dose may improve formulation value, although the supplied serving cost is not lower than the original.</p>
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<p>A substantial amount of magnesium citrate offers useful absorption and a focused formula. Its stated magnesium form and dose may improve formulation value, although the supplied serving cost is not lower than the original.</p>
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Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. The effect of food, vitamin, or mineral supplements on chronic constipation in adults: A systematic review and meta-analysis of randomized controlled trials.
    van der Schoot A; Creedon A; Whelan K; Dimidi E · Neurogastroenterology and motility · 2023
    Meta-analysis787 participants8 studies pooledDigestive Health forMagnesium
  2. A Randomized Double-blind Placebo-controlled Trial on the Effect of Magnesium Oxide in Patients With Chronic Constipation.
    Mori S; Tomita T; Fujimura K; Asano H; Ogawa T; Yamasaki T; Kondo T; Kono T; Tozawa K; Oshima T; Fukui H; Kimura T; Watari J; Miwa H · Journal of neurogastroenterology and motility · 2022
    Randomized trial34 participantsDigestive Health forMagnesium
  3. Lactobacillus reuteri DSM 17938 and Magnesium Oxide in Children with Functional Chronic Constipation: A Double-Blind and Randomized Clinical Trial.
    Kubota M; Ito K; Tomimoto K; Kanazaki M; Tsukiyama K; Kubota A; Kuroki H; Fujita M; Vandenplas Y · Nutrients · 2020
    Randomized trial60 participantsDigestive Health forMagnesium
  4. Diagnosis of magnesium-induced diarrhea.
    Fine KD; Santa Ana CA; Fordtran JS · The New England journal of medicine · 1991
    Clinical trial19 participantsDigestive Health forMagnesium
  5. Association between Serum Magnesium and Fractures: A Systematic Review and Meta-Analysis of Observational Studies.
    Dominguez LJ; Veronese N; Ciriminna S; Pérez-Albela JL; Vásquez-López VF; Rodas-Regalado S; Di Bella G; Parisi A; Tagliaferri F; Barbagallo M · Nutrients · 2023
    Meta-analysis119,755 participants4 studies pooledBone Health forMagnesium
  6. Bioabsorbable Magnesium-Based Materials Potential and Safety in Bone Surgery: A Systematic Review.
    Hung CH; Kwok YC; Yip J; Wong HH; Leung YY · Craniomaxillofacial trauma & reconstruction · 2025
    Systematic review386 participants8 studies pooledBone Health forMagnesium
  7. Vascularized bone grafting fixed by biodegradable magnesium screw for treating osteonecrosis of the femoral head.
    Zhao D; Huang S; Lu F; Wang B; Yang L; Qin L; Yang K; Li Y; Li W; Wang W; Tian S; Zhang X; Gao W; Wang Z; Zhang Y; Xie X; Wang J; Li J · Biomaterials · 2016
    Randomized trial48 participantsBone Health forMagnesium
  8. An update on magnesium and bone health.
    Rondanelli M; Faliva MA; Tartara A; Gasparri C; Perna S; Infantino V; Riva A; Petrangolini G; Peroni G · Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2022
    Narrative reviewBone Health forMagnesium
  9. Sex-specific differences in the association of magnesium intake with femoral neck bone mineral density among older adults.
    Wang B; Tan X; Yao X; Zhu Z · Endocrine connections · 2025
    Cross-sectional study1,343 participantsBone Health forMagnesium
  10. Circulating and dietary magnesium and risk of cardiovascular disease: a systematic review and meta-analysis of prospective studies.
    Del Gobbo LC; Imamura F; Wu JH; de Oliveira Otto MC; Chiuve SE; Mozaffarian D · The American journal of clinical nutrition · 2013
    Meta-analysis313,041 participants16 studies pooledCardiovascular Support forMagnesium
  11. Magnesium and the risk of cardiovascular events: a meta-analysis of prospective cohort studies.
    Qu X; Jin F; Hao Y; Li H; Tang T; Wang H; Yan W; Dai K · PloS one · 2013
    Meta-analysis532,979 participants19 studies pooledCardiovascular Support forMagnesium
  12. Quantitative Association Between Serum/Dietary Magnesium and Cardiovascular Disease/Coronary Heart Disease Risk: A Dose-Response Meta-analysis of Prospective Cohort Studies.
    Zhao L; Hu M; Yang L; Xu H; Song W; Qian Y; Zhao M · Journal of cardiovascular pharmacology · 2020
    Meta-analysis544,581 participants18 studies pooledCardiovascular Support Heart Health forMagnesium
  13. Comparative Efficacy of Nutraceuticals on Endothelial Function: A Systematic Review and Network Meta-Analysis.
    Norouzzadeh M; Rashedi MH; Mahdavi-Mazdeh G; Kosari A; Shahinfar H · Current atherosclerosis reports · 2026
    Meta-analysisCardiovascular Support Heart Health forMagnesium
  14. Serum magnesium, mortality, and cardiovascular disease in chronic kidney disease and end-stage renal disease patients: a systematic review and meta-analysis.
    Xiong J; He T; Wang M; Nie L; Zhang Y; Wang Y; Huang Y; Feng B; Zhang J; Zhao J · Journal of nephrology · 2020
    Meta-analysis200,934 participants20 studies pooledCardiovascular Support forMagnesium
  15. Efficacy of oral magnesium therapy in the treatment of chronic constipation in spastic cerebral palsy children: a randomized controlled trial.
    Hassanein SMA; Deifallah SM; Bastawy HA · World journal of pediatrics : WJP · 2021
    Randomized trial100 participantsDigestive Health forMagnesium
  16. Ca:Mg ratio, medium-chain fatty acids, and the gut microbiome.
    Fan L; Zhu X; Sun S; Yu C; Huang X; Ness R; Dugan LL; Shu L; Seidner DL; Murff HJ; Fodor AA; Azcarate-Peril MA; Shrubsole MJ; Dai Q · Clinical nutrition (Edinburgh, Scotland) · 2022
    Randomized trial240 participantsDigestive Health forMagnesium
  17. The Magnesium-Rich Formula for Functional Constipation in Infants: a Randomized Comparator-Controlled Study.
    Benninga MA; MENA Infant Constipation Study Group; Vandenplas Y · Pediatric gastroenterology, hepatology & nutrition · 2022
    Randomized trial286 participantsDigestive Health forMagnesium
  18. Magnesium treatment increases gut microbiome synthesizing vitamin D and inhibiting colorectal cancer: results from a double-blind precision-based randomized placebo-controlled trial.
    Sun E; Zhu X; Ness RM; Murff HJ; Sun S; Yu C; Fan L; Azcarate-Peril MA; Shrubsole MJ; Dai Q · The American journal of clinical nutrition · 2025
    Randomized trial240 participantsDigestive Health forMagnesium
  19. Magnesium-L-threonate improves sleep quality and daytime functioning in adults with self-reported sleep problems: A randomized controlled trial.
    Hausenblas HA; Lynch T; Hooper S; Shrestha A; Rosendale D; Gu J · Sleep medicine: X · 2025
    Randomized trial80 participantsEnergy forMagnesium
  20. Total magnesium intake and risk of frailty in older women.
    Struijk EA; Fung TT; Bischoff-Ferrari HA; Willett WC; Lopez-Garcia E · Journal of cachexia, sarcopenia and muscle · 2024
    Cohort study81,524 participantsEnergy forMagnesium
  21. Red blood cell magnesium and chronic fatigue syndrome.
    Cox IM; Campbell MJ; Dowson D · Lancet (London, England) · 1991
    Randomized trial32 participantsEnergy forMagnesium
  22. Exercise, magnesium and immune function.
    Laires MJ; Monteiro C · Magnesium research · 2008
    Narrative reviewEnergy forMagnesium
  23. Perioperative systemic magnesium to minimize postoperative pain: a meta-analysis of randomized controlled trials.
    De Oliveira GS; Castro-Alves LJ; Khan JH; McCarthy RJ · Anesthesiology · 2013
    Meta-analysis1,257 participants20 studies pooledGeneral Health forMagnesium
  24. Long-term outcome after intravenous magnesium sulphate in suspected acute myocardial infarction: the second Leicester Intravenous Magnesium Intervention Trial (LIMIT-2).
    Woods KL; Fletcher S · Lancet (London, England) · 1994
    Randomized trial2,316 participantsGeneral Health forMagnesium
  25. Association of magnesium sulfate use with mortality in critically ill patients with sepsis: a retrospective propensity score-matched cohort study.
    Gu WJ; Duan XJ; Liu XZ; Cen Y; Tao LY; Lyu J; Yin HY · British journal of anaesthesia · 2023
    Cohort study10,999 participantsGeneral Health forMagnesium
  26. Hypomagnesemia and Mortality in Incident Hemodialysis Patients.
    Li L; Streja E; Rhee CM; Mehrotra R; Soohoo M; Brunelli SM; Kovesdy CP; Kalantar-Zadeh K · American journal of kidney diseases : the official journal of the National Kidney Foundation · 2016
    Cohort study9,359 participantsGeneral Health forMagnesium
  27. The effects of magnesium supplementation on abnormal uterine bleeding, alopecia, quality of life, and acne in women with polycystic ovary syndrome: a randomized clinical trial.
    Jaripur M; Ghasemi-Tehrani H; Askari G; Gholizadeh-Moghaddam M; Clark CCT; Rouhani MH · Reproductive biology and endocrinology : RB&E · 2022
    Randomized trial64 participantsGeneral Health forMagnesium
  28. Effects of magnesium supplementation on improving hyperglycemia, hypercholesterolemia, and hypertension in type 2 diabetes: A pooled analysis of 24 randomized controlled trials.
    Xu L; Li X; Wang X; Xu M · Frontiers in nutrition · 2023
    Meta-analysis1,325 participants24 studies pooledHeart Health forMagnesium
  29. The effect of lowering blood pressure by magnesium supplementation in diabetic hypertensive adults with low serum magnesium levels: a randomized, double-blind, placebo-controlled clinical trial.
    Guerrero-Romero F; Rodríguez-Morán M · Journal of human hypertension · 2009
    Randomized trial82 participantsHeart Health forMagnesium
  30. Positive effects of magnesium supplementation in metabolic syndrome.
    Kisters S; Kisters K; Werner T; Vormann J; Tokmak F; Westhoff T; Gröber U; Predel HG; Reuter H · International journal of clinical pharmacology and therapeutics · 2024
    Randomized trial54 participantsHeart Health forMagnesium
  31. Role of magnesium supplementation in the treatment of depression: A randomized clinical trial.
    Tarleton EK; Littenberg B; MacLean CD; Kennedy AG; Daley C · PloS one · 2017
    Randomized trial126 participantsStress Relief forMagnesium
  32. Effects of Intravenous Esketamine or Magnesium Sulfate on Early Postoperative Negative Emotions and Pain in Patients Undergoing Endoscopic Sinus Surgery: A Randomized Controlled Trial.
    Wang L; Zhou J; Liu Q; Qian K; Wang L; Xie C · Therapeutics and clinical risk management · 2026
    Randomized trial137 participantsStress Relief forMagnesium
  33. Effect of short-term magnesium supplementation on anxiety, depression and sleep quality in patients after open-heart surgery.
    Saba S; Faizi F; Sepandi M; Nehrir B · Magnesium research · 2022
    Non-randomized trial60 participantsStress Relief forMagnesium
  34. Effects of dry needling compared to magnesium infiltration in trigger points for patients with myofascial pain syndrome: a randomized controlled study in Tunisia.
    Dhouibi J; Moncer R; Kalbousi N; Gaddour M; Laayouni S; Ouanes W; Kacem B; Jemni S · Korean journal of family medicine · 2026
    Randomized trial45 participantsStress Relief forMagnesium
  35. Effect of magnesium and vitamin B6 supplementation on mental health and quality of life in stressed healthy adults: Post-hoc analysis of a randomised controlled trial.
    Noah L; Dye L; Bois De Fer B; Mazur A; Pickering G; Pouteau E · Stress and health : journal of the International Society for the Investigation of Stress · 2021
    Randomized trialStress Relief forMagnesium
  36. Magnesium and anabolic hormones in older men.
    Maggio M; Ceda GP; Lauretani F; Cattabiani C; Avantaggiato E; Morganti S; Ablondi F; Bandinelli S; Dominguez LJ; Barbagallo M; Paolisso G; Semba RD; Ferrucci L · International journal of andrology · 2012
    Cohort study399 participantsTestosterone Support forMagnesium
  37. Analysis of the relationship between the blood concentration of several metals, macro- and micronutrients and endocrine disorders associated with male aging.
    Rotter I; Kosik-Bogacka DI; Dołęgowska B; Safranow K; Kuczyńska M; Laszczyńska M · Environmental geochemistry and health · 2017
    Cross-sectional study313 participantsTestosterone Support forMagnesium
  38. Effect of magnesium supplementation in improving hyperandrogenism, hirsutism, and sleep quality in women with polycystic ovary syndrome: A randomized, placebo-controlled clinical trial.
    Gholizadeh-Moghaddam M; Ghasemi-Tehrani H; Askari G; Jaripur M; Clark CCT; Rouhani MH · Health science reports · 2024
    Randomized trial64 participantsTestosterone Support forMagnesium
  39. The effects of trace element supplementation on glycolipid metabolism in PCOS: a systematic review and meta-analysis.
    Yang L; Gao Y; Zhao W; Qi Y; Duo X; Wang H · Frontiers in nutrition · 2025
    Meta-analysis1,600 participants25 studies pooledTestosterone Support forMagnesium
  40. Effects of magnesium supplementation on testosterone levels of athletes and sedentary subjects at rest and after exhaustion.
    Cinar V; Polat Y; Baltaci AK; Mogulkoc R · Biological trace element research · 2011
    Non-randomized trial20 participantsTestosterone Support forMagnesium