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UNIQUE OMEGA E+

A.C. Grace Company
4.4
★ ★ ★ ★ ★
(22 ratings)
Fish Oil 1500 mg
Product Image
Score63
A broad lipid and antioxidant blend with a favorable oil form, but undisclosed EPA and DHA keep its core potency uncertain.
How scoring works
Quantity:60 Softgel(s) • (30 servings)
Goals:
Cardiovascular Support
Anti-Inflammatory Support

Score 63

A broad lipid and antioxidant blend with a favorable oil form, but undisclosed EPA and DHA keep its core potency uncertain.
How scoring works
$37.63($1.25 per serving)
Pure Formulas
$ 53.31
iHerb
$ 37.63
Vitacost
$ 49.89
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Analysis

Triglyceride-form marine oil is a useful absorption feature, and natural vitamin E helps protect the oil from oxidation. CoQ10, carotenoids, and vitamin D broaden the formula beyond omega-3 support.

EPA and DHA quantities are the key missing facts. Without them, the substantial total oil amount cannot show whether the serving delivers meaningful cardiovascular or inflammatory support.

The vitamin E dose is unusually prominent and may suit someone specifically seeking mixed tocopherol and tocotrienol support. Anyone who mainly wants a clearly dosed omega-3 should choose a label that states its EPA and DHA yield.

Who is it for
  • Adults seeking combined omega-3 and antioxidant support
  • People who value triglyceride-form fish oil
Best for
  • A multi-nutrient cardiovascular support routine
  • Users specifically interested in natural vitamin E forms

Pros

  • Triglyceride-form marine oil
  • Includes tocopherol and tocotrienol vitamin E
  • Adds CoQ10, vitamin D3, and carotenoids
  • Focused softgel delivery

Cons

  • EPA and DHA amounts are not stated
  • Fish species and purification method are not provided
  • Active omega-3 value cannot be judged
  • CoQ10 amount is modest

Warnings

  • The high vitamin E exposure may increase bleeding tendency with anticoagulant or antiplatelet medicines.
  • Contains marine fish oil and is unsuitable for people with a fish allergy.

Nutrient quality

68 High impact

Triglyceride fish oil and natural vitamin E provide credible absorption and oxidation support. Missing EPA and DHA amounts prevent confirmation of a meaningful omega-three dose.

Ingredient transparency

74 High impact

Listed ingredient amounts and serving details are stated clearly. EPA and DHA amounts and a complete non-active ingredient list are not supplied.

Customer satisfaction

55 Moderate impact

The supplied average rating is favorable but less compelling than the leaders, and a small response volume makes the average rating less reliable. No comment-level feedback is supplied to judge recurring complaints or purpose-specific experiences.

Value for money

51 Moderate impact

High serving cost is difficult to justify without active omega-three disclosure. Formula focus and disclosure determine whether that value holds up in practice.

Report analysis

Goals

Cardiovascular Support
Cardiovascular Support
Impact
High effect
A- Goal FitC- Strength of SupportB- CoverageA- Formula Quality
Vitamin D · 600 IUCoenzyme Q-10 · 40 mgFish Oil · 1500 mgVitamin E · 192 mg

Fish oil, vitamin E, CoQ10, and carotenoids target lipid handling, oxidative stress, and cardiac energy. Human evidence is strong for adequate EPA and DHA, but the label does not disclose either active fatty acid.

Triglyceride-form fish oil and broad vitamin E forms support absorption and oxidation protection. The high vitamin E exposure may increase bleeding risk with anticoagulants, while the missing EPA and DHA amounts prevent confirmation of cardiovascular potency.

Study evidence
Fish Oil Supportive 185 studies
Vitamin E Mixed 79 studies
Anti-Inflammatory Support
Anti-Inflammatory Support
Impact
High effect
B Goal FitD- Strength of SupportC CoverageA- Formula Quality
Vitamin D · 600 IUFish Oil · 1500 mgCoenzyme Q-10 · 40 mgVitamin E · 192 mg

Fish oil, natural vitamin E, tocotrienols, CoQ10, and carotenoids create a relevant antioxidant and lipid-mediator formula. Evidence is strongest for EPA and DHA, but their amounts are not disclosed.

The triglyceride oil form and broad vitamin E profile improve quality and oxidation control. Missing fatty-acid yields prevent confirmation of the primary anti-inflammatory dose, while the supporting CoQ10 amount is modest.

Study evidence
Fish Oil Supportive 68 studies
Vitamin E Supportive 20 studies

Ingredients

IngredientAmount per serving
Total Fat
1.5 Gram(s)
Calories
14 {Calories}
Marine Fish Oil (Triglycerides)
 1500 mg
Vitamin E (D-Alpha-Tocopherol, Tocotrienols)
 192 mg
Vitamin D3 (Cholecalciferol)
 600 IU
Coenzyme Q10 (Ubiquinone)
 40 mg
natural Carotenoids
8 mg
Adults 18–50 Children 4+
Report overview
Fish Oil (Triglycerides) · 1500 mg OverallScore22
D- Active Ingredient Quality & BioavailabilityF Dose, Safety & Label TransparencyF Value

The triglyceride form supports absorption, while a substantial natural vitamin E blend protects against oxidation. Fish species, purification, and independent testing are not identified. EPA and DHA amounts are missing, so active potency, concentration, and cost efficiency remain unknown.

View ingredientView products
Loading alternative details
84 Performance

Mega EPA/DHA

Life Extension
Clearly listed EPA at 720 mg and DHA at 480 mg make the active omega-3 amount easy to assess. Compared with the original, the explicit EPA and DHA disclosure makes potency easier to judge and provides a more focused basis for cardiovascular and inflammatory support.
87 Performance

Omega-3

Solgar
Clearly listed EPA at 1008 mg and DHA at 756 mg make the active omega-3 amount easy to assess. Compared with the original, the explicit EPA and DHA disclosure makes potency easier to judge and provides a more focused basis for cardiovascular and inflammatory support.
84 Performance

Alaska Wild Fish Oil Mega Omega-3

21st Century
Clearly listed EPA at 965 mg and DHA at 385 mg make the active omega-3 amount easy to assess. Compared with the original, the explicit EPA and DHA disclosure makes potency easier to judge and provides a more focused basis for cardiovascular and inflammatory support.
82 Budget

Ultra Strength One-per-Day RxOmega-3

Natural Factors
The label states 900 mg of total omega-3 fatty acids, but its two DHA ethyl ester entries leave the EPA-to-DHA split unclear. Compared with the original, it lowers serving cost, but missing separate EPA and DHA amounts make the potency trade-off harder to judge.
79 Budget

Omega-3 Fish Oil with Vitamin D 1000 mg Lemon Flavored

Swanson
Clearly listed EPA at 180 mg and DHA at 120 mg make the active omega-3 amount easy to assess. Compared with the original, it lowers serving cost and gives clearer information about active EPA and DHA, although other added ingredients may be absent.
76 Budget

Omega-3 Fish Oil 1000 mg Lemon

Natrol
Clearly listed EPA at 180 mg and DHA at 120 mg make the active omega-3 amount easy to assess. Compared with the original, it lowers serving cost and gives clearer information about active EPA and DHA, although other added ingredients may be absent.
83 Value

Ultra Strength One-per-Day RxOmega-3 with Vitamin D3 25 mcg (1000IU)

Natural Factors
The label states 900 mg of total omega-3 fatty acids, but its two DHA ethyl ester entries leave the EPA-to-DHA split unclear. Compared with the original, serving economics are favorable, but the missing EPA and DHA breakdown limits confidence in the value comparison.
70 Value

Fish Oil 1000 mg

Spring Valley
A stated 260 mg of combined EPA and DHA makes the main omega-3 amount easy to assess. Compared with the original, clear EPA and DHA disclosure combines with favorable serving economics to improve practical value, while the formula remains focused.
67 Value

Super DPA Fish Oil 1000 mg

Swanson
1000 mg of fish oil is clearly listed, but the label does not state separate EPA and DHA amounts. Compared with the original, serving economics are favorable, but the missing EPA and DHA breakdown limits confidence in the value comparison.
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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Dose-dependent effects of fish oil on cardio-metabolic biomarkers in healthy middle-aged and elderly Chinese people: a double-blind randomized controlled trial.
    Song J; Hu M; Li C; Yang B; Ding Q; Wang C; Mao L · Food & function · 2018
    Randomized trial201 participantsAnti-Inflammatory Support forFish Oil
  2. Eicosapentaenoic acid supplementation alleviates pruritus, enhances skin moisture, and mitigates depression in maintenance hemodialysis patients.
    Lin YL; Wang CL; Chiang TI · Frontiers in nephrology · 2024
    Randomized trial60 participantsAnti-Inflammatory Support forFish Oil
  3. Lowering effects of fish oil supplementation on proinflammatory markers in hypertension: results from a randomized controlled trial.
    Yang B; Ren XL; Li ZH; Shi MQ; Ding F; Su KP; Guo XJ; Li D · Food & function · 2020
    Randomized trial77 participantsAnti-Inflammatory Support forFish Oil
  4. The effects of ω-3 fish oil emulsion-based parenteral nutrition plus combination treatment for acute paraquat poisoning.
    Meng Z; Dong Y; Gao H; Yao D; Gong Y; Meng Q; Zheng T; Cui X; Su X; Tian Y · The Journal of international medical research · 2019
    Randomized trial174 participantsAnti-Inflammatory Support forFish Oil
  5. Effects of Omega-3 Fatty Acid Intake in Patients Undergoing Dialysis: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
    Liu R; Jiang J; Fu Z; Liu C; Yao L; Quan H · Journal of the American Nutrition Association · 2022
    Meta-analysis49 studies pooledAnti-Inflammatory Support forFish Oil
  6. Effects of delta-tocotrienol supplementation on Glycemic Control, oxidative stress, inflammatory biomarkers and miRNA expression in type 2 diabetes mellitus: A randomized control trial.
    Mahjabeen W; Khan DA; Mirza SA; Pervez MA · Phytotherapy research : PTR · 2021
    Randomized trial110 participantsAnti-Inflammatory Support forVitamin E
  7. Effect of vitamin E supplementation on serum C-reactive protein level: a meta-analysis of randomized controlled trials.
    Saboori S; Shab-Bidar S; Speakman JR; Yousefi Rad E; Djafarian K · European journal of clinical nutrition · 2016
    Meta-analysis495 participants12 studies pooledAnti-Inflammatory Support forVitamin E
  8. Efficacy of Nutritional Interventions on Inflammatory Markers in Haemodialysis Patients: A Systematic Review and Limited Meta-Analysis.
    Khor BH; Narayanan SS; Sahathevan S; Gafor AHA; Daud ZAM; Khosla P; Sabatino A; Fiaccadori E; Chinna K; Karupaiah T · Nutrients · 2018
    Meta-analysis46 studies pooledAnti-Inflammatory Support forVitamin E
  9. Vitamin E improves serum markers and histology in adults with metabolic dysfunction-associated steatotic liver disease: Systematic review and meta-analysis.
    Chee NM; Sinnanaidu RP; Chan WK · Journal of gastroenterology and hepatology · 2024
    Meta-analysis8 studies pooledAnti-Inflammatory Support forVitamin E
  10. Delta-tocotrienol supplementation improves biochemical markers of hepatocellular injury and steatosis in patients with nonalcoholic fatty liver disease: A randomized, placebo-controlled trial.
    Pervez MA; Khan DA; Slehria AUR; Ijaz A · Complementary therapies in medicine · 2021
    Randomized trial71 participantsAnti-Inflammatory Support forVitamin E
  11. Marine Omega-3 Supplementation and Cardiovascular Disease: An Updated Meta-Analysis of 13 Randomized Controlled Trials Involving 127 477 Participants.
    Hu Y; Hu FB; Manson JE · Journal of the American Heart Association · 2020
    Meta-analysis127,477 participants13 studies pooledCardiovascular Support forFish Oil
  12. Impact of omega-3 fatty acids on hypertriglyceridemia, lipidomics, and gut microbiome in patients with type 2 diabetes.
    Lu J; Liu R; Ren H; Wang S; Hu C; Shi Z; Li M; Liu W; Wan Q; Su Q; Li Q; Zheng H; Qu S; Yang F; Ji H; Lin H; Qi H; Wu X; Wu K; Chen Y; Xu Y; Xu M; Wang T; Zheng J; Ning G; Zheng R; Bi Y; Zhong H; Wang W · Med (New York, N.Y.) · 2025
    Randomized trial309 participantsCardiovascular Support forFish Oil
  13. A systematic review of fish-oil supplements for the prevention and treatment of hypertension.
    Campbell F; Dickinson HO; Critchley JA; Ford GA; Bradburn M · European journal of preventive cardiology · 2013
    Meta-analysis1,524 participants17 studies pooledCardiovascular Support forFish Oil
  14. Effects of fish oil-derived fatty acids on suboptimal cardiovascular health: A multicenter, randomized, double-blind, placebo-controlled trial.
    Zeng Q; Dong SY; Liu YP; Fu J; Shuai P; Zhao ZM; Li TX · Nutrition, metabolism, and cardiovascular diseases : NMCD · 2017
    Randomized trial422 participantsCardiovascular Support forFish Oil
  15. Effect of High-Dose Marine Omega-3 Fatty Acids on Atherosclerosis: A Systematic Review and Meta-Analysis of Randomized Clinical Trials.
    Sekikawa A; Cui C; Sugiyama D; Fabio A; Harris WS; Zhang X · Nutrients · 2020
    Meta-analysis6 studies pooledCardiovascular Support forFish Oil
  16. Supplementation with vitamin E alone is associated with reduced myocardial infarction: a meta-analysis.
    Loffredo L; Perri L; Di Castelnuovo A; Iacoviello L; De Gaetano G; Violi F · Nutrition, metabolism, and cardiovascular diseases : NMCD · 2016
    Meta-analysis16 studies pooledCardiovascular Support forVitamin E
  17. Vitamin E ameliorates blood cholesterol level and alters gut microbiota composition: A randomized controlled trial.
    Chen B; Li Y; Li Z; Hu X; Zhen H; Chen H; Nie C; Hou Y; Zhu S; Xiao L; Li T · Nutrition, metabolism, and cardiovascular diseases : NMCD · 2025
    Randomized trial90 participantsCardiovascular Support forVitamin E
  18. Effects of long-term vitamin E supplementation on cardiovascular events and cancer: a randomized controlled trial.
    Lonn E; Bosch J; Yusuf S; Sheridan P; Pogue J; Arnold JM; Ross C; Arnold A; Sleight P; Probstfield J; Dagenais GR; HOPE and HOPE-TOO Trial Investigators · JAMA · 2005
    Randomized trial9,541 participantsCardiovascular Support forVitamin E
  19. Independent and combined associations of dietary antioxidant exposure with all-cause and cause-specific mortality in the general population.
    Liu Z; He Z; Xing Y · Journal of nutritional science · 2026
    Cohort study34,955 participantsCardiovascular Support forVitamin E
  20. Tocotrienol rich fraction supplementation improved lipid profile and oxidative status in healthy older adults: A randomized controlled study.
    Chin SF; Ibahim J; Makpol S; Abdul Hamid NA; Abdul Latiff A; Zakaria Z; Mazlan M; Mohd Yusof YA; Abdul Karim A; Wan Ngah WZ · Nutrition & metabolism · 2011
    Randomized trial62 participantsCardiovascular Support forVitamin E