Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.
- Effects of vitamin D supplementation on markers for cardiovascular disease and type 2 diabetes: an individual participant data meta-analysis of randomized controlled trials.
Swart KM; Lips P; Brouwer IA; Jorde R; Heymans MW; Grimnes G; Grübler MR; Gaksch M; Tomaschitz A; Pilz S; Eiriksdottir G; Gudnason V; Wamberg L; Rejnmark L; Sempos CT; Durazo-Arvizu RA; Dowling KG; Hull G; Škrabáková Z; Kiely M; Cashman KD; van Schoor NM · The American journal of clinical nutrition · 2019
Meta-analysis2,994 participants12 studies pooledflagCardiovascular Support forscienceVitamin D
- Vitamin D supplementation and hospitalization for infection in older adults: A post-hoc analysis of data from the Australian D-Health Trial.
Pham H; Waterhouse M; Baxter C; Romero BD; McLeod DS; Armstrong BK; Ebeling PR; English DR; Hartel G; O'Connell RL; van der Pols JC; Venn AJ; Webb PM; Whiteman DC; Neale RE · The American journal of clinical nutrition · 2023
Randomized trial21,315 participantsflagImmunity forscienceVitamin D
- Vitamin D and risk of cause specific death: systematic review and meta-analysis of observational cohort and randomised intervention studies.
Chowdhury R; Kunutsor S; Vitezova A; Oliver-Williams C; Chowdhury S; Kiefte-de-Jong JC; Khan H; Baena CP; Prabhakaran D; Hoshen MB; Feldman BS; Pan A; Johnson L; Crowe F; Hu FB; Franco OH · BMJ (Clinical research ed.) · 2014
Meta-analysis95 studies pooledflagGeneral Health forscienceVitamin D
- Effects of Vitamin D Supplementation on Cardiovascular and Glycemic Biomarkers.
Miao J; Bachmann KN; Huang S; Su YR; Dusek J; Newton-Cheh C; Arora P; Wang TJ · Journal of the American Heart Association · 2021
Randomized trial289 participantsflagAnti-Inflammatory Support forscienceVitamin D
- Vitamin D deficiency as a risk factor for cognitive decline in individuals aged 50 or older.
Cochar-Soares N; da Silva TBP; Luiz MM; Tofani PS; Delinocente MLB; de Oliveira Máximo R; Steptoe A; de Oliveira C; da Silva Alexandre T · GeroScience · 2026
Cohort study2,625 participantsflagCognitive Support forscienceVitamin D
- A placebo-controlled trial of omega-3 fatty acid (ethyl eicosapentaenoic acid) supplementation for residual symptoms and cognitive impairment in schizophrenia.
Fenton WS; Dickerson F; Boronow J; Hibbeln JR; Knable M · The American journal of psychiatry · 2002
Randomized trial87 participantsflagCognitive Support forscienceEPA (Eicosapentaenoic Acid)
- Vitamin D for the management of multiple sclerosis.
Jagannath VA; Filippini G; Di Pietrantonj C; Asokan GV; Robak EW; Whamond L; Robinson SA · The Cochrane database of systematic reviews · 2018
Meta-analysis933 participants12 studies pooledflagEnergy forscienceVitamin D
- Effect of cholecalciferol supplementation on arterial stiffness: a systematic review and meta-analysis.
Upala S; Sanguankeo A; Congrete S; Jaruvongvanich V · Scandinavian cardiovascular journal : SCJ · 2017
Meta-analysis547 participants7 studies pooledflagCardiovascular Support forscienceVitamin D
- Effect of vitamin D status and vitamin D supplementation on immune function and prevention of acute respiratory tract infections in dark-skinned individuals: a systematic review and meta-analysis.
Bournot AR; Darling AL; Givens ID; Lovegrove JA; Lanham-New SA; Hart KH · Public health nutrition · 2024
Meta-analysis36,707 participants18 studies pooledflagImmunity forscienceVitamin D
- Vitamin D supplementation in people with IBS has no effect on symptom severity and quality of life: results of a randomised controlled trial.
Williams CE; Williams EA; Corfe BM · European journal of nutrition · 2022
Randomized trial135 participantsflagGeneral Health forscienceVitamin D
- Could vitamin D reduce obesity-associated inflammation? Observational and Mendelian randomization study.
Palaniswamy S; Gill D; De Silva NM; Lowry E; Jokelainen J; Karhu T; Mutt SJ; Dehghan A; Sliz E; Chasman DI; Timonen M; Viinamäki H; Keinänen-Kiukaanniemi S; Hyppönen E; Herzig KH; Sebert S; Järvelin MR · The American journal of clinical nutrition · 2020
Observational study3,586 participantsflagAnti-Inflammatory Support forscienceVitamin D
- Severe vitamin D deficiency and risk of mild cognitive impairment in patients with chronic kidney disease: A cohort study.
Li YY; Weng HL; Lai YC; Hung KC · Medicine · 2025
Cohort study35,090 participantsflagCognitive Support forscienceVitamin D
- Fish intake, n-3 fatty acid body status, and risk of cognitive decline: a systematic review and a dose-response meta-analysis of observational and experimental studies.
Kosti RI; Kasdagli MI; Kyrozis A; Orsini N; Lagiou P; Taiganidou F; Naska A · Nutrition reviews · 2022
Meta-analysis5 studies pooledflagCognitive Support forscienceEPA (Eicosapentaenoic Acid)
- Vitamin D levels and menopause-related symptoms.
LeBlanc ES; Desai M; Perrin N; Wactawski-Wende J; Manson JE; Cauley JA; Michael YL; Tang J; Womack C; Song Y; Johnson KC; O'Sullivan MJ; Woods N; Stefanick ML · Menopause (New York, N.Y.) · 2015
Cross-sectional study530 participantsflagEnergy forscienceVitamin D
- Effect of Early High-Dose Vitamin D3 Repletion on Cognitive Outcomes in Critically Ill Adults.
Han JH; Ginde AA; Brown SM; Baughman A; Collar EM; Ely EW; Gong MN; Hope AA; Hou PC; Hough CL; Iwashyna TJ; Jackson JC; Khan A; Orun OM; Patel MB; Raman R; Rice TW; Ringwood N; Semler MW; Shapiro NI; Talmor DS; Self WH; Vitamin D to Improve Outcomes by Leveraging Early Treatment Network Investigators · Chest · 2022
Randomized trial95 participantsflagCognitive Support forscienceVitamin D
- Effects of Vitamin D3 Supplementation on Muscle Strength, Mass, and Physical Performance in Women with Vitamin D Insufficiency: A Randomized Placebo-Controlled Trial.
Bislev LS; Langagergaard Rødbro L; Rolighed L; Sikjaer T; Rejnmark L · Calcified tissue international · 2019
Randomized trial81 participantsflagGeneral Health forscienceVitamin D
- Vitamin D status and Its association with haematological inflammatory indices and cardiometabolic risk profiles: a retrospective cross-sectional study.
Al-Essa YM; Aljumah HK; Al Saeed ZY; AlQattan RA; Alquwayzani DY; Al-Yousef GK; Al Owdah AS; Alzuwayr MA; Elsheikh E · Frontiers in cardiovascular medicine · 2026
Cross-sectional study1,100 participantsflagCardiovascular Support forscienceVitamin D
- The relationship between dietary lipids and cognitive performance in an elderly population.
González S; Huerta JM; Fernández S; Patterson AM; Lasheras C · International journal of food sciences and nutrition · 2010
Cohort study304 participantsflagCognitive Support forscienceEPA (Eicosapentaenoic Acid)
- [The impact of the severity of chronic sinusitis with nasal polyps and the coexistence of Th2-type inflammation on 25(OH) D and pulmonary function].
He J; Yang F; Zhang Y; Zhang N; Hu J; Feng N; Wen W; Shen X; Zhao Y; Ma R · Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2026
Observational study159 participantsflagAnti-Inflammatory Support forscienceVitamin D
- Association Between Vitamin D and Influenza: Meta-Analysis and Systematic Review of Randomized Controlled Trials.
Zhu Z; Zhu X; Gu L; Zhan Y; Chen L; Li X · Frontiers in nutrition · 2022
Meta-analysis4,859 participants10 studies pooledflagImmunity forscienceVitamin D
- Vitamin D Supplementation in Adolescents and Young Adults With Juvenile Systemic Lupus Erythematosus for Improvement in Disease Activity and Fatigue Scores: A Randomized, Double-Blind, Placebo-Controlled Trial.
Lima GL; Paupitz J; Aikawa NE; Takayama L; Bonfa E; Pereira RM · Arthritis care & research · 2016
Randomized trial40 participantsflagEnergy forscienceVitamin D
- Vitamin D supplementation for prevention of mortality in adults.
Bjelakovic G; Gluud LL; Nikolova D; Whitfield K; Wetterslev J; Simonetti RG; Bjelakovic M; Gluud C · The Cochrane database of systematic reviews · 2014
Meta-analysis95,286 participants159 studies pooledflagGeneral Health forscienceVitamin D
- Vitamin D deficiency and C-reactive protein: a bidirectional Mendelian randomization study.
Zhou A; Hyppönen E · International journal of epidemiology · 2023
Observational study294,970 participantsflagAnti-Inflammatory Support forscienceVitamin D
- Cardiovascular disease and vitamin D supplementation: trial analysis, systematic review, and meta-analysis.
Ford JA; MacLennan GS; Avenell A; Bolland M; Grey A; Witham M; RECORD Trial Group · The American journal of clinical nutrition · 2015
Meta-analysis13,033 participants21 studies pooledflagCardiovascular Support forscienceVitamin D
- Effect of moderate or high versus low dose daily vitamin D on COVID-19 incidence: A double-blind, parallel-group randomized clinical trial.
Meltzer DO; Moy JN; Schram AW; Tate A; Hyman MJ; Cursio JF; Vokes T; Yeo KJ; Prochaska M; Jacobs JJ; Solway J · Clinical nutrition (Edinburgh, Scotland) · 2026
Randomized trial955 participantsflagImmunity forscienceVitamin D
- Effects of vitamin D supplementation on cognitive function and blood Aβ-related biomarkers in older adults with Alzheimer's disease: a randomised, double-blind, placebo-controlled trial.
Jia J; Hu J; Huo X; Miao R; Zhang Y; Ma F · Journal of neurology, neurosurgery, and psychiatry · 2020
Randomized trial210 participantsflagCognitive Support forscienceVitamin D
- Blood polyunsaturated omega-3 fatty acids, brain atrophy, cognitive decline, and dementia risk.
Thomas A; Baillet M; Proust-Lima C; Féart C; Foubert-Samier A; Helmer C; Catheline G; Samieri C · Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024
Cohort study1,279 participantsflagCognitive Support forscienceEPA (Eicosapentaenoic Acid)
- Effect of Vitamin D Supplementation on Fatigue in Multiple Sclerosis: A Systematic Review and Meta-Analysis.
López-Muñoz P; Torres-Costoso AI; Fernández-Rodríguez R; Guzmán-Pavón MJ; de Arenas-Arroyo SN; Basco-López JÁ; Reina-Gutiérrez S · Nutrients · 2023
Meta-analysis345 participants5 studies pooledflagEnergy forscienceVitamin D
- Vitamin D in Children With Inflammatory Bowel Disease: A Randomized Controlled Clinical Trial.
El Amrousy D; El Ashry H; Hodeib H; Hassan S · Journal of clinical gastroenterology · 2021
Randomized trial120 participantsflagAnti-Inflammatory Support forscienceVitamin D
- The effects of vitamin D on all-cause mortality in different diseases: an evidence-map and umbrella review of 116 randomized controlled trials.
Cao M; He C; Gong M; Wu S; He J · Frontiers in nutrition · 2023
Meta-analysis149,865 participants116 studies pooledflagGeneral Health forscienceVitamin D
- Cholecalciferol treatment to reduce blood pressure in older patients with isolated systolic hypertension: the VitDISH randomized controlled trial.
Witham MD; Price RJ; Struthers AD; Donnan PT; Messow CM; Ford I; McMurdo ME · JAMA internal medicine · 2014
Randomized trial159 participantsflagCardiovascular Support forscienceVitamin D
- Vitamin D Supplementation Improves Cognitive Function Through Reducing Oxidative Stress Regulated by Telomere Length in Older Adults with Mild Cognitive Impairment: A 12-Month Randomized Controlled Trial.
Yang T; Wang H; Xiong Y; Chen C; Duan K; Jia J; Ma F · Journal of Alzheimer's disease : JAD · 2021
Randomized trial183 participantsflagCognitive Support forscienceVitamin D
- Impact of Vitamin D Supplementation on Influenza Vaccine Response and Immune Functions in Deficient Elderly Persons: A Randomized Placebo-Controlled Trial.
Goncalves-Mendes N; Talvas J; Dualé C; Guttmann A; Corbin V; Marceau G; Sapin V; Brachet P; Evrard B; Laurichesse H; Vasson MP · Frontiers in immunology · 2019
Randomized trial38 participantsflagImmunity forscienceVitamin D
- Thirteen-year prospective study between fish consumption, long-chain n-3 fatty acids intakes and cognitive function.
Kesse-Guyot E; Péneau S; Ferry M; Jeandel C; Hercberg S; Galan P; SU.VI.MAX 2 Research Group · The journal of nutrition, health & aging · 2011
Cohort study3,294 participantsflagCognitive Support forscienceEPA (Eicosapentaenoic Acid)
- Vitamin D in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome After COVID-19 or Vaccination: A Randomized Controlled Trial.
Kodama S; Nakata M; Konishi N; Yoshino M; Fujisawa A; Naganuma M; Kobayashi Y; Hirai Y; Kitagawa A; Miyokawa M; Mishima R; Teramukai S; Fukushima M · Nutrients · 2026
Randomized trial91 participantsflagEnergy forscienceVitamin D
- Effects of Vitamin D3 on asymmetric- and symmetric dimethylarginine in arterial hypertension.
Grübler MR; Gaksch M; Kienreich K; Verheyen ND; Schmid J; Müllner C; Richtig G; Scharnagl H; Trummer C; Schwetz V; Meinitzer A; Pieske B; März W; Tomaschitz A; Pilz S · The Journal of steroid biochemistry and molecular biology · 2017
Randomized trial200 participantsflagCardiovascular Support forscienceVitamin D
- Vitamin D supplementation for prevention of cancer in adults.
Bjelakovic G; Gluud LL; Nikolova D; Whitfield K; Krstic G; Wetterslev J; Gluud C · The Cochrane database of systematic reviews · 2015
Meta-analysis50,623 participants18 studies pooledflagGeneral Health forscienceVitamin D
- Effect of Vitamin D Supplementation on Inflammatory Markers in Non-Obese Lebanese Patients with Type 2 Diabetes: A Randomized Controlled Trial.
El Hajj C; Walrand S; Helou M; Yammine K · Nutrients · 2021
Randomized trial88 participantsflagAnti-Inflammatory Support forscienceVitamin D
- High-dose oral vitamin D supplementation for prevention of infections in children aged 0 to 59 months: a systematic review and meta-analysis.
Carboo JA; Dolman-Macleod RC; Malan L; Lombard MJ · Nutrition reviews · 2024
Meta-analysis5,748 participants7 studies pooledflagImmunity forscienceVitamin D
- Effect of vitamin D on cognitive decline: results from two ancillary studies of the VITAL randomized trial.
Kang JH; Vyas CM; Okereke OI; Ogata S; Albert M; Lee IM; D'Agostino D; Buring JE; Cook NR; Grodstein F; Manson JE · Scientific reports · 2022
Randomized trialflagCognitive Support forscienceVitamin D
- The effects of vitamin D supplementation on disease activity and fatigue in Libyan rheumatoid arthritis patients.
Elfituri S · Reumatologia · 2024
Randomized trial68 participantsflagEnergy forscienceVitamin D
- Serum ω-3 Fatty Acids and Cognitive Domains in Community-Dwelling Older Adults from the NuAge Study: Exploring the Associations with Other Fatty Acids and Sex.
Duchaine CS; Fiocco AJ; Carmichael PH; Cunnane SC; Plourde M; Lampuré A; Allès B; Belleville S; Gaudreau P; Presse N; Ferland G; Laurin D · The Journal of nutrition · 2022
Cross-sectional study386 participantsflagCognitive Support forscienceEPA (Eicosapentaenoic Acid)
- No effect of high-dose vitamin D supplementation on glycemic status or cardiovascular risk factors in subjects with prediabetes.
Sollid ST; Hutchinson MY; Fuskevåg OM; Figenschau Y; Joakimsen RM; Schirmer H; Njølstad I; Svartberg J; Kamycheva E; Jorde R · Diabetes care · 2015
Randomized trial511 participantsflagCardiovascular Support forscienceVitamin D
- Effect of vitamin D3 supplementation on cellular immunity and inflammatory markers in COVID-19 patients admitted to the ICU.
Bychinin MV; Klypa TV; Mandel IA; Yusubalieva GM; Baklaushev VP; Kolyshkina NA; Troitsky AV · Scientific reports · 2022
Randomized trial110 participantsflagImmunity forscienceVitamin D
- Vitamin D status and incident cardiovascular disease and all-cause mortality: a general population study.
Skaaby T; Husemoen LL; Pisinger C; Jørgensen T; Thuesen BH; Fenger M; Linneberg A · Endocrine · 2013
Cohort study9,146 participantsflagGeneral Health forscienceVitamin D
- Effects of Vitamin D3 and Marine Omega-3 Fatty Acids Supplementation on Biomarkers of Systemic Inflammation: 4-Year Findings from the VITAL Randomized Trial.
Dong Y; Zhu H; Chen L; Huang Y; Christen W; Cook NR; Copeland T; Mora S; Buring JE; Lee IM; Costenbader KH; Manson JE · Nutrients · 2022
Randomized trial1,054 participantsflagAnti-Inflammatory Support forscienceVitamin D
- Vitamin D supplementation and incident dementia: Effects of sex, APOE, and baseline cognitive status.
Ghahremani M; Smith EE; Chen HY; Creese B; Goodarzi Z; Ismail Z · Alzheimer's & dementia (Amsterdam, Netherlands) · 2024
Cohort study12,388 participantsflagCognitive Support forscienceVitamin D
- Role of vitamin D as adjuvant therapy on multiple sclerosis: an updated systematic review and meta-analysis of randomized controlled trials.
Serag I; Abouzid M; Alsaadany KR; Hendawy M; Ali HT; Yaseen Y; Moawad MHED · European journal of medical research · 2025
Meta-analysis1,903 participants21 studies pooledflagEnergy forscienceVitamin D
- Association of Red Blood Cell Omega-3 Fatty Acids With MRI Markers and Cognitive Function in Midlife: The Framingham Heart Study.
Satizabal CL; Himali JJ; Beiser AS; Ramachandran V; Melo van Lent D; Himali D; Aparicio HJ; Maillard P; DeCarli CS; Harris WS; Seshadri S · Neurology · 2023
Cross-sectional study2,183 participantsflagCognitive Support forscienceEPA (Eicosapentaenoic Acid)
- Vitamin D Supplementation, Serum 25(OH)D Concentrations and Cardiovascular Disease Risk Factors: A Systematic Review and Meta-Analysis.
Mirhosseini N; Rainsbury J; Kimball SM · Frontiers in cardiovascular medicine · 2020
Meta-analysis81 studies pooledflagCardiovascular Support flagHeart Health forscienceVitamin D
- The impact of vitamin D administration on mortality in COVID-19 patients: a systematic review and meta-analysis of randomized controlled trials.
Kow CS; Ramachandram DS; Hasan SS; Wong Z; Thiruchelvam K · Inflammopharmacology · 2024
Meta-analysis2,495 participants19 studies pooledflagGeneral Health forscienceVitamin D
- Current opinion on the role of vitamin D supplementation in respiratory infections and asthma/COPD exacerbations: A need to establish publication guidelines for overcoming the unpublished data.
Anitua E; Tierno R; Alkhraisat MH · Clinical nutrition (Edinburgh, Scotland) · 2022
Meta-analysis50,554 participants65 studies pooledflagImmunity forscienceVitamin D
- Dietary vitamin D intake and 2-year changes in cognitive function in older adults with overweight or obesity and metabolic syndrome.
Vázquez-Lorente H; Ni J; Paz-Graniel I; Toledo E; Corella D; Castañer O; Martínez JA; Alonso-Gómez ÁM; Wärnberg J; Vioque J; Romaguera D; López-Miranda J; Estruch R; Tinahones FJ; Lapetra J; Serra-Majem L; Bouzalmate-Hajjaj A; Tur JA; Pérez RMM; Fanlo M; Delgado-Rodríguez M; Bustelo AB; Vidal J; Vázquez C; Daimiel L; Ros E; Fernández-Aranda F; Rognoni T; Babio N; Asensio EM; Pérez-Vega KA; Garcia-Rios A; Compañ-Gabucio L; Cueto-Galán R; Zulet MA; Nafria M; Casas R; Cano-Ibáñez N; Tojal-Sierra L; Gómez-Pérez AM; Goñi N; Sorli JV; Zomeño MD; Arenas-Larriva AP; Jiménez-Sellés P; Basterra-Gortari J; Fitó M; Salas-Salvadó J · GeroScience · 2025
Cohort study5,454 participantsflagCognitive Support forscienceVitamin D
- Vitamin D and inflammation.
Cannell JJ; Grant WB; Holick MF · Dermato-endocrinology · 2015
Systematic review39 studies pooledflagAnti-Inflammatory Support forscienceVitamin D
- Effect of Vitamin D Supplementation on the Prognosis of Post-stroke Fatigue: A Retrospective Cohort Study.
Wang L; Zhao XM; Wang FY; Wu JC; Wang Y · Frontiers in neurology · 2021
Cohort study139 participantsflagEnergy forscienceVitamin D
- Omega-3 Long-Chain Polyunsaturated Fatty Acids: Are They Beneficial for Physical and Cognitive Functioning in Older Adults?
Erhardt R; Cardoso BR; Meyer BJ; Brownell S; O'Connell S; Mirzaee S; Duckham RL; Macpherson H · The journal of nutrition, health & aging · 2021
Cross-sectional study142 participantsflagCognitive Support forscienceEPA (Eicosapentaenoic Acid)
- A Randomized Trial of Vitamin D Supplementation on Vascular Function in CKD.
Kumar V; Yadav AK; Lal A; Kumar V; Singhal M; Billot L; Gupta KL; Banerjee D; Jha V · Journal of the American Society of Nephrology : JASN · 2017
Randomized trial120 participantsflagCardiovascular Support forscienceVitamin D
- Vitamin D for the Prevention of Disease: An Endocrine Society Clinical Practice Guideline.
Demay MB; Pittas AG; Bikle DD; Diab DL; Kiely ME; Lazaretti-Castro M; Lips P; Mitchell DM; Murad MH; Powers S; Rao SD; Scragg R; Tayek JA; Valent AM; Walsh JME; McCartney CR · The Journal of clinical endocrinology and metabolism · 2024
Guideline / consensusflagGeneral Health forscienceVitamin D
- Cholecalciferol decreases inflammation and improves vitamin D regulatory enzymes in lymphocytes in the uremic environment: A randomized controlled pilot trial.
Carvalho JTG; Schneider M; Cuppari L; Grabulosa CC; T Aoike D; Q Redublo BM; C Batista M; Cendoroglo M; Maria Moyses R; Dalboni MA · PloS one · 2017
Randomized trial44 participantsflagImmunity forscienceVitamin D
- Oral Vitamin D Rapidly Attenuates Inflammation from Sunburn: An Interventional Study.
Scott JF; Das LM; Ahsanuddin S; Qiu Y; Binko AM; Traylor ZP; Debanne SM; Cooper KD; Boxer R; Lu KQ · The Journal of investigative dermatology · 2017
Randomized trial20 participantsflagAnti-Inflammatory Support forscienceVitamin D
- Effect of 2000 IU compared with 800 IU vitamin D on cognitive performance among adults age 60 years and older: a randomized controlled trial.
Schietzel S; Fischer K; Brugger P; Orav EJ; Renerts K; Gagesch M; Freystaetter G; Stähelin HB; Egli A; Bischoff-Ferrari HA · The American journal of clinical nutrition · 2020
Randomized trial273 participantsflagCognitive Support forscienceVitamin D
- The effect of home-based aerobic training and vitamin D supplementation on fatigue and quality of life in patients with multiple sclerosis during COVID-19 outbreak.
Bahmani E; Hoseini R; Amiri E · Science & sports · 2022
Randomized trial40 participantsflagEnergy forscienceVitamin D
- Eicosapentaenoic and docosahexaenoic acids, cognition, and behavior in children with attention-deficit/hyperactivity disorder: a randomized controlled trial.
Milte CM; Parletta N; Buckley JD; Coates AM; Young RM; Howe PR · Nutrition (Burbank, Los Angeles County, Calif.) · 2012
Randomized trial90 participantsflagCognitive Support forscienceEPA (Eicosapentaenoic Acid)
- Effect of vitamin D3 supplementation on vascular and metabolic health of vitamin D-deficient overweight and obese children: a randomized clinical trial.
Rajakumar K; Moore CG; Khalid AT; Vallejo AN; Virji MA; Holick MF; Greenspan SL; Arslanian S; Reis SE · The American journal of clinical nutrition · 2020
Randomized trial225 participantsflagCardiovascular Support forscienceVitamin D
- Vitamin D Status and Mortality: A Systematic Review of Observational Studies.
Heath AK; Kim IY; Hodge AM; English DR; Muller DC · International journal of environmental research and public health · 2019
Systematic review84 studies pooledflagGeneral Health forscienceVitamin D
- Effect of weekly vitamin D supplementation on the severity of atopic dermatitis and type 2 immunity biomarkers in children: A randomized controlled trial.
Borzutzky A; Iturriaga C; Pérez-Mateluna G; Cristi F; Cifuentes L; Silva-Valenzuela S; Vera-Kellet C; Cabalín C; Hoyos-Bachiloglu R; Navarrete-Dechent C; Cossio ML; Le Roy C; Camargo CA · Journal of the European Academy of Dermatology and Venereology : JEADV · 2024
Randomized trial101 participantsflagImmunity forscienceVitamin D
- Vitamin D supplementation reduces infection rate and promotes wound healing in patients with diabetic foot ulcers.
Gao YQ; Gao YH; Xing JH · World journal of diabetes · 2025
Randomized trial120 participantsflagAnti-Inflammatory Support forscienceVitamin D
- The impact of vitamin D food fortification and health outcomes in children: a systematic review and meta-regression.
Al Khalifah R; Alsheikh R; Alnasser Y; Alsheikh R; Alhelali N; Naji A; Al Backer N · Systematic reviews · 2021
Meta-analysis20 studies pooledflagCognitive Support forscienceVitamin D
- Fatigue and Vitamin D Status in Frail Elderly with and without Cancer, and Healthy Controls of Different Ages: Results from the IMAGE Study.
Dahlén E; Hedman C; Mily A; Alisjahbana A; Spulber G; Holmström-Edstedt J; Bergman P; Buggert M; Björkhem-Bergman L · Gerontology · 2025
Cohort study273 participantsflagEnergy forscienceVitamin D
- Breast milk EPA associated with infant distractibility when EPA level is low.
Jia K; Feng Y; Brenna JT; Luo ZC; Zhao J; Li H; Li P; Zhang Q; Zhao Q; Dai Q; Zhong Y; Lambers T; Zhang H; Zhou H; Gao Y · Nutrition (Burbank, Los Angeles County, Calif.) · 2021
Cohort study120 participantsflagCognitive Support forscienceEPA (Eicosapentaenoic Acid)
- Effect of omega-3 fatty acids on the telomere length: A mini meta-analysis of clinical trials.
Ali S; Scapagnini G; Davinelli S · Biomolecular concepts · 2022
Meta-analysis337 participants5 studies pooledflagAnti-Aging forscienceOmega-3
- Omega-3 supplementation and stress reactivity of cellular aging biomarkers: an ancillary substudy of a randomized, controlled trial in midlife adults.
Madison AA; Belury MA; Andridge R; Renna ME; Rosie Shrout M; Malarkey WB; Lin J; Epel ES; Kiecolt-Glaser JK · Molecular psychiatry · 2022
Randomized trial138 participantsflagAnti-Aging forscienceOmega-3
- Omega-3 Polyunsaturated Fatty Acids and Cognitive Decline in Adults with Non-Dementia or Mild Cognitive Impairment: An Overview of Systematic Reviews.
Barros MI; Brandão T; Irving SC; Alves P; Gomes F; Correia M · Nutrients · 2025
Meta-analysis26,881 participants9 studies pooledflagAnti-Aging forscienceOmega-3
- Association of marine omega-3 fatty acid levels with telomeric aging in patients with coronary heart disease.
Farzaneh-Far R; Lin J; Epel ES; Harris WS; Blackburn EH; Whooley MA · JAMA · 2010
Cohort study608 participantsflagAnti-Aging forscienceOmega-3
- Long-chain omega-3 fatty acids improve brain function and structure in older adults.
Witte AV; Kerti L; Hermannstädter HM; Fiebach JB; Schreiber SJ; Schuchardt JP; Hahn A; Flöel A · Cerebral cortex (New York, N.Y. : 1991) · 2015
Randomized trial65 participantsflagAnti-Aging forscienceOmega-3
- Joint association of serum 25-hydroxyvitamin D concentration and body mass index on the acceleration of clinical biomarker-based biological aging.
Pan Z; Zeng J; Chen Z; Chen S; Yang J; Li H; Wang S; Wang J; Li N; Gong Y; Liu M; Li C · The journals of gerontology. Series A, Biological sciences and medical sciences · 2026
Cohort study389,217 participantsflagAnti-Aging forscienceVitamin D
- Serum 25-Hydroxyvitamin D Levels as an Aging Marker: Strong Associations With Age and All-Cause Mortality Independent From Telomere Length, Epigenetic Age Acceleration, and 8-Isoprostane Levels.
Schöttker B; Hagen L; Zhang Y; Gào X; Holleczek B; Gao X; Brenner H · The journals of gerontology. Series A, Biological sciences and medical sciences · 2019
Cohort study9,940 participantsflagAnti-Aging forscienceVitamin D
- Sex-specific associations of serum 25-hydroxyvitamin D concentrations with incident sarcopenia in older adults: A 2-year follow-up study.
Song S; Lim JY; Kim M; Won CW; Park HY · The journal of nutrition, health & aging · 2025
Cohort study1,292 participantsflagAnti-Aging forscienceVitamin D
- Vitamin D deficit is associated with accelerated brain aging in the general population.
Terock J; Bonk S; Frenzel S; Wittfeld K; Garvert L; Hosten N; Nauck M; Völzke H; Van der Auwera S; Grabe HJ · Psychiatry research. Neuroimaging · 2022
Cross-sectional study1,865 participantsflagAnti-Aging forscienceVitamin D
- Vitamin D intake is associated with dementia risk in the Washington Heights-Inwood Columbia Aging Project (WHICAP).
Zhao C; Tsapanou A; Manly J; Schupf N; Brickman AM; Gu Y · Alzheimer's & dementia : the journal of the Alzheimer's Association · 2021
Cohort study1,759 participantsflagAnti-Aging forscienceVitamin D
- Low dietary vitamin E intake is associated with high risk of incident dementia among older adults: The Shanghai Aging Study.
Liu S; Luo J; Xiao Z; Wu W; Liang X; Ding S; Zhao Q; Zhao X; Wang Y; Ding D · Frontiers in nutrition · 2024
Cohort study1,550 participantsflagAnti-Aging forscienceVitamin E
- Nutrients and bioactives in green leafy vegetables and cognitive decline: Prospective study.
Morris MC; Wang Y; Barnes LL; Bennett DA; Dawson-Hughes B; Booth SL · Neurology · 2019
Cohort study960 participantsflagAnti-Aging forscienceVitamin E
- Low Intake of Vitamin E Accelerates Cellular Aging in Patients With Established Cardiovascular Disease: The CORDIOPREV Study.
Corina A; Rangel-Zúñiga OA; Jiménez-Lucena R; Alcalá-Díaz JF; Quintana-Navarro G; Yubero-Serrano EM; López-Moreno J; Delgado-Lista J; Tinahones F; Ordovás JM; López-Miranda J; Pérez-Martínez P · The journals of gerontology. Series A, Biological sciences and medical sciences · 2020
Observational study1,002 participantsflagAnti-Aging forscienceVitamin E
- The L-shaped link between total antioxidant capacity and phenotypic age acceleration: evidence from NHANES 2003-2010.
Wu Y; Xiang M; Zhao Y; Zhang Y; Cheng W; Deng J · Biogerontology · 2025
Cross-sectional study16,395 participantsflagAnti-Aging forscienceVitamin E
- Serum levels of vitamin E forms and risk of cognitive impairment in a Finnish cohort of older adults.
Mangialasche F; Solomon A; Kåreholt I; Hooshmand B; Cecchetti R; Fratiglioni L; Soininen H; Laatikainen T; Mecocci P; Kivipelto M · Experimental gerontology · 2014
Cohort study140 participantsflagAnti-Aging forscienceVitamin E
- Dose-dependent effects of fish oil on cardio-metabolic biomarkers in healthy middle-aged and elderly Chinese people: a double-blind randomized controlled trial.
Song J; Hu M; Li C; Yang B; Ding Q; Wang C; Mao L · Food & function · 2018
Randomized trial201 participantsflagAnti-Inflammatory Support forscienceFish Oil
- Eicosapentaenoic acid supplementation alleviates pruritus, enhances skin moisture, and mitigates depression in maintenance hemodialysis patients.
Lin YL; Wang CL; Chiang TI · Frontiers in nephrology · 2024
Randomized trial60 participantsflagAnti-Inflammatory Support forscienceFish Oil
- Lowering effects of fish oil supplementation on proinflammatory markers in hypertension: results from a randomized controlled trial.
Yang B; Ren XL; Li ZH; Shi MQ; Ding F; Su KP; Guo XJ; Li D · Food & function · 2020
Randomized trial77 participantsflagAnti-Inflammatory Support forscienceFish Oil
- The effects of ω-3 fish oil emulsion-based parenteral nutrition plus combination treatment for acute paraquat poisoning.
Meng Z; Dong Y; Gao H; Yao D; Gong Y; Meng Q; Zheng T; Cui X; Su X; Tian Y · The Journal of international medical research · 2019
Randomized trial174 participantsflagAnti-Inflammatory Support forscienceFish Oil
- Effects of Omega-3 Fatty Acid Intake in Patients Undergoing Dialysis: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
Liu R; Jiang J; Fu Z; Liu C; Yao L; Quan H · Journal of the American Nutrition Association · 2022
Meta-analysis49 studies pooledflagAnti-Inflammatory Support forscienceFish Oil
- Associations of C-reactive Protein with 25-hydroxyvitamin D in 24 Specific Diseases: A Cross-sectional Study from NHANES.
Yang F; Sun M; Sun C; Li J; Yang X; Bi C; Wang M; Pu L; Wang J; Wang C; Xie M; Yao Y; Jin L · Scientific reports · 2020
Cross-sectional study9,809 participantsflagAnti-Inflammatory Support forscienceVitamin D
- Combined effects of vitamin D deficiency and systemic inflammation on all-cause mortality and cause-specific mortality in older adults.
Zhang C; Cui J; Li S; Shen J; Luo X; Yao Y; Shi H · BMC geriatrics · 2024
Cohort study3,072 participantsflagAnti-Inflammatory Support forscienceVitamin D
- Effects of delta-tocotrienol supplementation on Glycemic Control, oxidative stress, inflammatory biomarkers and miRNA expression in type 2 diabetes mellitus: A randomized control trial.
Mahjabeen W; Khan DA; Mirza SA; Pervez MA · Phytotherapy research : PTR · 2021
Randomized trial110 participantsflagAnti-Inflammatory Support forscienceVitamin E
- Effect of vitamin E supplementation on serum C-reactive protein level: a meta-analysis of randomized controlled trials.
Saboori S; Shab-Bidar S; Speakman JR; Yousefi Rad E; Djafarian K · European journal of clinical nutrition · 2016
Meta-analysis495 participants12 studies pooledflagAnti-Inflammatory Support forscienceVitamin E
- Efficacy of Nutritional Interventions on Inflammatory Markers in Haemodialysis Patients: A Systematic Review and Limited Meta-Analysis.
Khor BH; Narayanan SS; Sahathevan S; Gafor AHA; Daud ZAM; Khosla P; Sabatino A; Fiaccadori E; Chinna K; Karupaiah T · Nutrients · 2018
Meta-analysis46 studies pooledflagAnti-Inflammatory Support forscienceVitamin E
- Vitamin E improves serum markers and histology in adults with metabolic dysfunction-associated steatotic liver disease: Systematic review and meta-analysis.
Chee NM; Sinnanaidu RP; Chan WK · Journal of gastroenterology and hepatology · 2024
Meta-analysis8 studies pooledflagAnti-Inflammatory Support forscienceVitamin E
- Delta-tocotrienol supplementation improves biochemical markers of hepatocellular injury and steatosis in patients with nonalcoholic fatty liver disease: A randomized, placebo-controlled trial.
Pervez MA; Khan DA; Slehria AUR; Ijaz A · Complementary therapies in medicine · 2021
Randomized trial71 participantsflagAnti-Inflammatory Support forscienceVitamin E
- Marine Omega-3 Supplementation and Cardiovascular Disease: An Updated Meta-Analysis of 13 Randomized Controlled Trials Involving 127 477 Participants.
Hu Y; Hu FB; Manson JE · Journal of the American Heart Association · 2020
Meta-analysis127,477 participants13 studies pooledflagCardiovascular Support forscienceFish Oil
- Impact of omega-3 fatty acids on hypertriglyceridemia, lipidomics, and gut microbiome in patients with type 2 diabetes.
Lu J; Liu R; Ren H; Wang S; Hu C; Shi Z; Li M; Liu W; Wan Q; Su Q; Li Q; Zheng H; Qu S; Yang F; Ji H; Lin H; Qi H; Wu X; Wu K; Chen Y; Xu Y; Xu M; Wang T; Zheng J; Ning G; Zheng R; Bi Y; Zhong H; Wang W · Med (New York, N.Y.) · 2025
Randomized trial309 participantsflagCardiovascular Support forscienceFish Oil
- A systematic review of fish-oil supplements for the prevention and treatment of hypertension.
Campbell F; Dickinson HO; Critchley JA; Ford GA; Bradburn M · European journal of preventive cardiology · 2013
Meta-analysis1,524 participants17 studies pooledflagCardiovascular Support forscienceFish Oil
- Effects of fish oil-derived fatty acids on suboptimal cardiovascular health: A multicenter, randomized, double-blind, placebo-controlled trial.
Zeng Q; Dong SY; Liu YP; Fu J; Shuai P; Zhao ZM; Li TX · Nutrition, metabolism, and cardiovascular diseases : NMCD · 2017
Randomized trial422 participantsflagCardiovascular Support forscienceFish Oil
- Effect of High-Dose Marine Omega-3 Fatty Acids on Atherosclerosis: A Systematic Review and Meta-Analysis of Randomized Clinical Trials.
Sekikawa A; Cui C; Sugiyama D; Fabio A; Harris WS; Zhang X · Nutrients · 2020
Meta-analysis6 studies pooledflagCardiovascular Support forscienceFish Oil
- Comparative Efficacy of Nutraceuticals on Endothelial Function: A Systematic Review and Network Meta-Analysis.
Norouzzadeh M; Rashedi MH; Mahdavi-Mazdeh G; Kosari A; Shahinfar H · Current atherosclerosis reports · 2026
Meta-analysisflagCardiovascular Support flagHeart Health forscienceVitamin D
- Randomized, placebo-controlled, double-blind clinical trial on the contributions of vitamin D in the control of cardiovascular risk factors, depressive symptoms and suicide risk.
Porto C; Petribu K; Barbosa N; Magalhães R; Lira C; Porto AB; Markman-Filho B; Lordsleem A; Calado E; Magalhães J; Sougey E; Silva T; Junio A; Bandeira F; Leão R · American heart journal plus : cardiology research and practice · 2025
Randomized trial224 participantsflagCardiovascular Support forscienceVitamin D
- Dose responses of vitamin D3 supplementation on arterial stiffness in overweight African Americans with vitamin D deficiency: A placebo controlled randomized trial.
Raed A; Bhagatwala J; Zhu H; Pollock NK; Parikh SJ; Huang Y; Havens R; Kotak I; Guo DH; Dong Y · PloS one · 2017
Randomized trial70 participantsflagCardiovascular Support forscienceVitamin D
- Paricalcitol and endothelial function in chronic kidney disease trial.
Zoccali C; Curatola G; Panuccio V; Tripepi R; Pizzini P; Versace M; Bolignano D; Cutrupi S; Politi R; Tripepi G; Ghiadoni L; Thadhani R; Mallamaci F · Hypertension (Dallas, Tex. : 1979) · 2015
Randomized trial88 participantsflagCardiovascular Support flagHeart Health forscienceVitamin D
- Supplementation with vitamin E alone is associated with reduced myocardial infarction: a meta-analysis.
Loffredo L; Perri L; Di Castelnuovo A; Iacoviello L; De Gaetano G; Violi F · Nutrition, metabolism, and cardiovascular diseases : NMCD · 2016
Meta-analysis16 studies pooledflagCardiovascular Support forscienceVitamin E
- Vitamin E ameliorates blood cholesterol level and alters gut microbiota composition: A randomized controlled trial.
Chen B; Li Y; Li Z; Hu X; Zhen H; Chen H; Nie C; Hou Y; Zhu S; Xiao L; Li T · Nutrition, metabolism, and cardiovascular diseases : NMCD · 2025
Randomized trial90 participantsflagCardiovascular Support forscienceVitamin E
- Effects of long-term vitamin E supplementation on cardiovascular events and cancer: a randomized controlled trial.
Lonn E; Bosch J; Yusuf S; Sheridan P; Pogue J; Arnold JM; Ross C; Arnold A; Sleight P; Probstfield J; Dagenais GR; HOPE and HOPE-TOO Trial Investigators · JAMA · 2005
Randomized trial9,541 participantsflagCardiovascular Support forscienceVitamin E
- Independent and combined associations of dietary antioxidant exposure with all-cause and cause-specific mortality in the general population.
Liu Z; He Z; Xing Y · Journal of nutritional science · 2026
Cohort study34,955 participantsflagCardiovascular Support forscienceVitamin E
- Tocotrienol rich fraction supplementation improved lipid profile and oxidative status in healthy older adults: A randomized controlled study.
Chin SF; Ibahim J; Makpol S; Abdul Hamid NA; Abdul Latiff A; Zakaria Z; Mazlan M; Mohd Yusof YA; Abdul Karim A; Wan Ngah WZ · Nutrition & metabolism · 2011
Randomized trial62 participantsflagCardiovascular Support forscienceVitamin E
- Gestational vitamin D concentration and child cognitive development: a longitudinal cohort study in the Environmental influences on Child Health Outcomes Program.
Melough MM; McGrath M; Palmore M; Collett BR; Kerver JM; Hockett CW; Schmidt RJ; Kelly RS; Lyall K; Zhao Q; Hipwell AE; Korrick SA; Gilbert-Diamond D; Weiss ST; Chu SH; Mirzakhani H; Porter JM; Sathyanarayana S; ECHO Cohort Consortium · The American journal of clinical nutrition · 2025
Cohort study912 participantsflagCognitive Support forscienceVitamin D
- Omega-3 Fatty Acid Supplementation for 12 Weeks Increases Resting and Exercise Metabolic Rate in Healthy Community-Dwelling Older Females.
Logan SL; Spriet LL · PloS one · 2016
Randomized trial24 participantsflagEnergy forscienceFish Oil
- Effects of fish oil during hemodialysis on nutritional status and quality of life: a randomized double-blinded trial.
Zhang C; Ge C; Wang J; Sun D · Food & nutrition research · 2022
Randomized trial103 participantsflagEnergy flagGeneral Health forscienceFish Oil
- Supplementation of fish oil and olive oil in patients with rheumatoid arthritis.
Berbert AA; Kondo CR; Almendra CL; Matsuo T; Dichi I · Nutrition (Burbank, Los Angeles County, Calif.) · 2005
Randomized trial43 participantsflagEnergy forscienceFish Oil flagJoint Health forscienceOmega-3
- DHA-rich Fish Oil Increases the Omega-3 Index and Lowers the Oxygen Cost of Physiologically Stressful Cycling in Trained Individuals.
Hingley L; Macartney MJ; Brown MA; McLennan PL; Peoples GE · International journal of sport nutrition and exercise metabolism · 2018
Randomized trial26 participantsflagEnergy forscienceFish Oil
- Fish oil reduces heart rate and oxygen consumption during exercise.
Peoples GE; McLennan PL; Howe PR; Groeller H · Journal of cardiovascular pharmacology · 2009
Randomized trial16 participantsflagEnergy forscienceFish Oil
- Parenteral Nutrition Containing Fish Oil for Hospitalized Non-Intensive Care Unit (ICU) Patients: A Systematic Review, Meta-Analysis, and Cost-Effectiveness Analysis.
Pradelli L; Heller AR; Klek S; Mayer K; Rosenthal MD; Muscaritoli M · Nutrients · 2025
Meta-analysis29 studies pooledflagGeneral Health forscienceFish Oil
- The effects of fish oil plus vitamin D3 intervention on non-alcoholic fatty liver disease: a randomized controlled trial.
Guo XF; Wang C; Yang T; Ma WJ; Zhai J; Zhao T; Xu TC; Li J; Liu H; Sinclair AJ; Li D · European journal of nutrition · 2022
Randomized trial111 participantsflagGeneral Health forscienceFish Oil
- Circulating Docosahexaenoic Acid and Risk of All-Cause and Cause-Specific Mortality.
O'Keefe EL; O'Keefe JH; Tintle NL; Westra J; Albuisson L; Harris WS · Mayo Clinic proceedings · 2024
Meta-analysis117,702 participants17 studies pooledflagGeneral Health forscienceFish Oil
- Omega-3 dietary supplements and the risk of cardiovascular events: a systematic review.
Marik PE; Varon J · Clinical cardiology · 2010
Meta-analysis39,044 participants11 studies pooledflagGeneral Health forscienceFish Oil
- Effect of vitamin D on gastrointestinal symptoms and health-related quality of life in irritable bowel syndrome patients: a randomized double-blind clinical trial.
Abbasnezhad A; Amani R; Hajiani E; Alavinejad P; Cheraghian B; Ghadiri A · Neurogastroenterology and motility · 2018
Randomized trial90 participantsflagGeneral Health forscienceVitamin D
- Meta-analysis of long-term vitamin D supplementation on overall mortality.
Zheng Y; Zhu J; Zhou M; Cui L; Yao W; Liu Y · PloS one · 2014
Meta-analysis42 studies pooledflagGeneral Health forscienceVitamin D
- Effects of eicosapentaenoic acid on major coronary events in hypercholesterolaemic patients (JELIS): a randomised open-label, blinded endpoint analysis.
Yokoyama M; Origasa H; Matsuzaki M; Matsuzawa Y; Saito Y; Ishikawa Y; Oikawa S; Sasaki J; Hishida H; Itakura H; Kita T; Kitabatake A; Nakaya N; Sakata T; Shimada K; Shirato K; Japan EPA lipid intervention study (JELIS) Investigators · Lancet (London, England) · 2007
Randomized trial18,645 participantsflagHeart Health forscienceEPA (Eicosapentaenoic Acid)
- Effects of EPA on coronary artery disease in hypercholesterolemic patients with multiple risk factors: sub-analysis of primary prevention cases from the Japan EPA Lipid Intervention Study (JELIS).
Saito Y; Yokoyama M; Origasa H; Matsuzaki M; Matsuzawa Y; Ishikawa Y; Oikawa S; Sasaki J; Hishida H; Itakura H; Kita T; Kitabatake A; Nakaya N; Sakata T; Shimada K; Shirato K; JELIS Investigators, Japan · Atherosclerosis · 2008
Randomized trial14,981 participantsflagHeart Health forscienceEPA (Eicosapentaenoic Acid)
- Effects of omega-3 fatty acids on coronary revascularization and cardiovascular events: a meta-analysis.
Dinu M; Sofi F; Lotti S; Colombini B; Mattioli AV; Catapano AL; Casula M; Baragetti A; Wong ND; Steg PG; Ambrosio G · European journal of preventive cardiology · 2024
Meta-analysis134,144 participants18 studies pooledflagHeart Health forscienceEPA (Eicosapentaenoic Acid)
- Incremental effects of eicosapentaenoic acid on cardiovascular events in statin-treated patients with coronary artery disease.
Matsuzaki M; Yokoyama M; Saito Y; Origasa H; Ishikawa Y; Oikawa S; Sasaki J; Hishida H; Itakura H; Kita T; Kitabatake A; Nakaya N; Sakata T; Shimada K; Shirato K; Matsuzawa Y; JELIS Investigators · Circulation journal : official journal of the Japanese Circulation Society · 2009
Randomized trialflagHeart Health forscienceEPA (Eicosapentaenoic Acid)
- Omega-3 Fatty Acids for the Management of Hypertriglyceridemia: A Science Advisory From the American Heart Association.
Skulas-Ray AC; Wilson PWF; Harris WS; Brinton EA; Kris-Etherton PM; Richter CK; Jacobson TA; Engler MB; Miller M; Robinson JG; Blum CB; Rodriguez-Leyva D; de Ferranti SD; Welty FK; American Heart Association Council on Arteriosclerosis, Thrombosis and Vascular Biology; Council on Lifestyle and Cardiometabolic Health; Council on Cardiovascular Disease in the Young; Council on Cardiovascular and Stroke Nursing; and Council on Clinical Cardiology · Circulation · 2020
OtherflagHeart Health forscienceEPA (Eicosapentaenoic Acid)
- Vitamin D supplementation for cardiometabolic risk markers in pregnant women based on the gestational diabetes mellitus or obesity status : a randomized clinical trial.
Yin WJ; Wang P; Ma SS; Tao RX; Hu HL; Jiang XM; Zhang Y; Tao FB; Zhu P · European journal of nutrition · 2024
Randomized trial1,537 participantsflagHeart Health forscienceVitamin D
- Does vitamin D supplementation modulate metabolic risk factors of cardiovascular disease? A systematic review and meta-analysis of clinical trials.
Abumweis S; Alqadi S; Al Tarteer A; Alrefai W; Alzoughool F; Jew S; Qudah T · Asia Pacific journal of clinical nutrition · 2026
Meta-analysis45 studies pooledflagHeart Health forscienceVitamin D
- Effects of omega-3 fatty acids on hyper-inflammatory response and clinical outcomes in critically ill patients: a meta-analysis.
Liu T; Wang X; Wang XH; Wang C; Cai JZ; Wang HF · Intensive & critical care nursing · 2025
Meta-analysis3,152 participants41 studies pooledflagImmunity forscienceOmega-3
- Effect of ω-3 polyunsaturated fatty acid-supplemented parenteral nutrition on inflammatory and immune function in postoperative patients with gastrointestinal malignancy: A meta-analysis of randomized control trials in China.
Zhao Y; Wang C · Medicine · 2018
Meta-analysis1,008 participants16 studies pooledflagImmunity forscienceOmega-3
- Effects of omega-3 fatty acids on patients undergoing surgery for gastrointestinal malignancy: a systematic review and meta-analysis.
Yu J; Liu L; Zhang Y; Wei J; Yang F · BMC cancer · 2017
Meta-analysis623 participants9 studies pooledflagImmunity forscienceOmega-3
- Omega-3 PUFA supplementation and the response to evoked endotoxemia in healthy volunteers.
Ferguson JF; Mulvey CK; Patel PN; Shah RY; Doveikis J; Zhang W; Tabita-Martinez J; Terembula K; Eiden M; Koulman A; Griffin JL; Mehta NN; Shah R; Propert KJ; Song WL; Reilly MP · Molecular nutrition & food research · 2015
Randomized trial60 participantsflagImmunity forscienceOmega-3
- Omega-3 fatty acid supplementation during pregnancy and respiratory symptoms in children.
Escamilla-Nuñez MC; Barraza-Villarreal A; Hernández-Cadena L; Navarro-Olivos E; Sly PD; Romieu I · Chest · 2014
Randomized trial1,094 participantsflagImmunity forscienceOmega-3
- Vitamin D supplementation to prevent acute respiratory infections: individual participant data meta-analysis.
Martineau AR; Jolliffe DA; Greenberg L; Aloia JF; Bergman P; Dubnov-Raz G; Esposito S; Ganmaa D; Ginde AA; Goodall EC; Grant CC; Janssens W; Jensen ME; Kerley CP; Laaksi I; Manaseki-Holland S; Mauger D; Murdoch DR; Neale R; Rees JR; Simpson S; Stelmach I; Trilok Kumar G; Urashima M; Camargo CA; Griffiths CJ; Hooper RL · Health technology assessment (Winchester, England) · 2020
Meta-analysis11,321 participants25 studies pooledflagImmunity forscienceVitamin D
- Vitamin D3 and deconvoluting a rash.
Ernst MK; Evans ST; Techner JM; Rothbaum RM; Christensen LF; Onay UV; Biyashev D; Demczuk MM; Nguyen CV; Honda KS; McCormick TS; Tsoi LC; Gudjonsson JE; Cooper KD; Lu KQ · JCI insight · 2023
Randomized trial28 participantsflagImmunity forscienceVitamin D
- Krill oil improved osteoarthritic knee pain in adults with mild to moderate knee osteoarthritis: a 6-month multicenter, randomized, double-blind, placebo-controlled trial.
Stonehouse W; Benassi-Evans B; Bednarz J; Vincent AD; Hall S; Hill CL · The American journal of clinical nutrition · 2022
Randomized trial235 participantsflagJoint Health forscienceOmega-3
- Effects of omega-3 supplementation on lipid metabolism, inflammation, and disease activity in rheumatoid arthritis: a meta-analysis of randomized controlled trials.
Wang W; Xu Y; Zhou J; Zang Y · Clinical rheumatology · 2024
Meta-analysis1,018 participants18 studies pooledflagJoint Health forscienceOmega-3
- Impact of type and dose of oral polyunsaturated fatty acid supplementation on disease activity in inflammatory rheumatic diseases: a systematic literature review and meta-analysis.
Sigaux J; Mathieu S; Nguyen Y; Sanchez P; Letarouilly JG; Soubrier M; Czernichow S; Flipo RM; Sellam J; Daïen C · Arthritis research & therapy · 2022
Meta-analysis1,420 participants30 studies pooledflagJoint Health forscienceOmega-3
- A meta-analysis of the analgesic effects of omega-3 polyunsaturated fatty acid supplementation for inflammatory joint pain.
Goldberg RJ; Katz J · Pain · 2007
Meta-analysis17 studies pooledflagJoint Health forscienceOmega-3
- Knee effusion-synovitis volume measurement and effects of vitamin D supplementation in patients with knee osteoarthritis.
Wang X; Cicuttini F; Jin X; Wluka AE; Han W; Zhu Z; Blizzard L; Antony B; Winzenberg T; Jones G; Ding C · Osteoarthritis and cartilage · 2018
Randomized trial413 participantsflagJoint Health forscienceVitamin D
- Vitamin D Deficiency Leads to Poorer Health Outcomes and Greater Length of Stay After Total Knee Arthroplasty and Supplementation Improves Outcomes: A Systematic Review and Meta-Analysis.
Vivek K; Kamal R; Perera E; Gupte CM · JBJS reviews · 2024
Meta-analysis146,054 participants10 studies pooledflagJoint Health forscienceVitamin D
- Does vitamin D improve symptomatic and structural outcomes in knee osteoarthritis? A systematic review and meta-analysis.
Zhao ZX; He Y; Peng LH; Luo X; Liu M; He CS; Chen J · Aging clinical and experimental research · 2021
Meta-analysis1,599 participants6 studies pooledflagJoint Health forscienceVitamin D
- Baseline 25-hydroxyvitamin D levels predict the effects of vitamin D supplementation on joint symptoms and cartilage loss in patients with knee osteoarthritis.
Wang T; Zheng S; Jin X; Cen H; Zhu Z; Han W; Wluka A; Cicuttini F; Cao P; Ding C · Rheumatology advances in practice · 2025
Randomized trial413 participantsflagJoint Health forscienceVitamin D
- The Efficacy and Safety of Disease-Modifying Osteoarthritis Drugs for Knee and Hip Osteoarthritis-a Systematic Review and Network Meta-Analysis.
Yang W; Sun C; He SQ; Chen JY; Wang Y; Zhuo Q · Journal of general internal medicine · 2021
Meta-analysis11,890 participants28 studies pooledflagJoint Health forscienceVitamin D
- The influence of n-3 polyunsaturated fatty acids on cognitive function in individuals without dementia: a systematic review and dose-response meta-analysis.
Suh SW; Lim E; Burm SY; Lee H; Bae JB; Han JW; Kim KW · BMC medicine · 2024
Meta-analysis9,660 participants24 studies pooledflagMental Focus forscienceEPA (Eicosapentaenoic Acid)
- EPA supplementation improves teacher-rated behaviour and oppositional symptoms in children with ADHD.
Gustafsson PA; Birberg-Thornberg U; Duchén K; Landgren M; Malmberg K; Pelling H; Strandvik B; Karlsson T · Acta paediatrica (Oslo, Norway : 1992) · 2011
Randomized trial92 participantsflagMental Focus forscienceEPA (Eicosapentaenoic Acid)
- Docosahexaenoic Acid (DHA) and Eicosapentaenoic Acid (EPA)-Should They Be Mandatory Supplements in Pregnancy?
Amza M; Haj Hamoud B; Sima RM; Dinu MD; Gorecki GP; Popescu M; Gică N; Poenaru MO; Pleș L · Biomedicines · 2024
Narrative reviewflagMental Focus forscienceEPA (Eicosapentaenoic Acid)
- Supplementation with oil rich in eicosapentaenoic acid, but not in docosahexaenoic acid, improves global cognitive function in healthy, young adults: results from randomized controlled trials.
Patan MJ; Kennedy DO; Husberg C; Hustvedt SO; Calder PC; Khan J; Forster J; Jackson PA · The American journal of clinical nutrition · 2021
Randomized trial310 participantsflagMental Focus forscienceEPA (Eicosapentaenoic Acid)
- Three Doses of Vitamin D and Cognitive Outcomes in Older Women: A Double-Blind Randomized Controlled Trial.
Castle M; Fiedler N; Pop LC; Schneider SJ; Schlussel Y; Sukumar D; Hao L; Shapses SA · The journals of gerontology. Series A, Biological sciences and medical sciences · 2021
Randomized trialflagMental Focus forscienceVitamin D
- Vitamin D and executive function: a preliminary report.
Hansen AL; Dahl L; Bakke L; Thayer JF · Perceptual and motor skills · 2012
Cross-sectional study25 participantsflagMental Focus forscienceVitamin D
- Effects of Vitamin D Supplementation on Cognitive Function in Older Adults: A Grading of Recommendations Assessment, Development, and Evaluation (GRADE) Methodology-Assessed Systematic Review and Meta-Analysis of Randomized Clinical Trials.
Behrouzi R; Shahinfar H; Jazayeri S · Nutrition reviews · 2026
Meta-analysis9 studies pooledflagMental Focus forscienceVitamin D
- Maternal vitamin D concentrations are associated with faster childhood reaction time and response speed, but not with motor fluency and flexibility, at the age of 5-6 years: the Amsterdam Born Children and their Development (ABCD) Study.
Brouwer-Brolsma EM; Vrijkotte TGM; Feskens EJM · The British journal of nutrition · 2019
Cohort study1,854 participantsflagMental Focus forscienceVitamin D
- Serum 25-hydroxyvitamin D and cognitive decline in the very old: the Newcastle 85+ Study.
Granic A; Hill TR; Kirkwood TB; Davies K; Collerton J; Martin-Ruiz C; von Zglinicki T; Saxby BK; Wesnes KA; Collerton D; Mathers JC; Jagger C · European journal of neurology · 2015
Cohort study775 participantsflagMental Focus forscienceVitamin D
- Effects of omega-3 supplementation on glucose and lipid metabolism in patients with gestational diabetes: A meta-analysis of randomized controlled trials.
Liu W; Gao M; Yang S; Sun C; Bi Y; Li Y; Wang J; Yuan X · Journal of diabetes and its complications · 2023
Meta-analysis331 participants6 studies pooledflagMetabolism Boost forscienceOmega-3
- Hepatic de novo lipogenesis is suppressed and fat oxidation is increased by omega-3 fatty acids at the expense of glucose metabolism.
Green CJ; Pramfalk C; Charlton CA; Gunn PJ; Cornfield T; Pavlides M; Karpe F; Hodson L · BMJ open diabetes research & care · 2021
Randomized trial38 participantsflagMetabolism Boost forscienceOmega-3
- Clinical and metabolic response to flaxseed oil omega-3 fatty acids supplementation in patients with diabetic foot ulcer: A randomized, double-blind, placebo-controlled trial.
Soleimani Z; Hashemdokht F; Bahmani F; Taghizadeh M; Memarzadeh MR; Asemi Z · Journal of diabetes and its complications · 2018
Randomized trial60 participantsflagMetabolism Boost flagSkin Health forscienceOmega-3
- The Effects of Flaxseed Oil Omega-3 Fatty Acids Supplementation on Metabolic Status of Patients with Polycystic Ovary Syndrome: A Randomized, Double-Blind, Placebo-Controlled Trial.
Mirmasoumi G; Fazilati M; Foroozanfard F; Vahedpoor Z; Mahmoodi S; Taghizadeh M; Esfeh NK; Mohseni M; Karbassizadeh H; Asemi Z · Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association · 2018
Randomized trial60 participantsflagMetabolism Boost forscienceOmega-3
- A combination of omega-3 and plant sterols regulate glucose and lipid metabolism in individuals with impaired glucose regulation: a randomized and controlled clinical trial.
Wang JF; Zhang HM; Li YY; Xia S; Wei Y; Yang L; Wang D; Ye JJ; Li HX; Yuan J; Pan RR · Lipids in health and disease · 2019
Randomized trial200 participantsflagMetabolism Boost forscienceOmega-3
- Effects of vitamin D supplementation on insulin resistance and lipid metabolic profiles in women with gestational diabetes mellitus: A randomized controlled trial.
Duan Y; Zhang S; Ma X; Li L; Jia K · African journal of reproductive health · 2026
Randomized trial120 participantsflagMetabolism Boost forscienceVitamin D
- Vitamin D3 improves glucose metabolism and attenuates inflammation in prediabetic human and mice.
Zhang Y; Ni P; Miao Y; Chen H; Tang L; Song H; Li W; Li X · The Journal of nutritional biochemistry · 2024
Randomized trialflagMetabolism Boost forscienceVitamin D
- Effects of vitamin D and calcium supplementation on pancreatic β cell function, insulin sensitivity, and glycemia in adults at high risk of diabetes: the Calcium and Vitamin D for Diabetes Mellitus (CaDDM) randomized controlled trial.
Mitri J; Dawson-Hughes B; Hu FB; Pittas AG · The American journal of clinical nutrition · 2011
Randomized trial92 participantsflagMetabolism Boost forscienceVitamin D
- The Effects of Vitamin D Supplementation on Glycemic Control, Lipid Profiles and C-Reactive Protein Among Patients with Cardiovascular Disease: a Systematic Review and Meta-Analysis of Randomized Controlled Trials.
Ostadmohammadi V; Milajerdi A; Ghayour-Mobarhan M; Ferns G; Taghizadeh M; Badehnoosh B; Mirzaei H; Asemi Z · Current pharmaceutical design · 2020
Meta-analysis630 participants8 studies pooledflagMetabolism Boost forscienceVitamin D
- The Effect of Improved Serum 25-Hydroxyvitamin D Status on Glycemic Control in Diabetic Patients: A Meta-Analysis.
Mirhosseini N; Vatanparast H; Mazidi M; Kimball SM · The Journal of clinical endocrinology and metabolism · 2017
Meta-analysis1,528 participants24 studies pooledflagMetabolism Boost forscienceVitamin D
- Dietetic intervention in psoriatic arthritis: the DIETA trial.
Leite BF; Morimoto MA; Gomes CMF; Klemz BNC; Genaro PS; Shivappa N; Hébert JR; Damasceno NRT; Pinheiro MM · Advances in rheumatology (London, England) · 2022
Randomized trial97 participantsflagSkin Health forscienceOmega-3
- Omega-3 fatty acid supplement skin cancer prophylaxis in lung transplant recipients: A randomized, controlled pilot trial.
Miura K; Vail A; Chambers D; Hopkins PM; Ferguson L; Grant M; Rhodes LE; Green AC · The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · 2019
Randomized trial49 participantsflagSkin Health forscienceOmega-3
- Treatment of hard-to-heal wounds in ischaemic lower extremities with a novel fish skin-derived matrix.
Lee YJ; Han HJ; Shim HS · Journal of wound care · 2024
Randomized trial50 participantsflagSkin Health forscienceOmega-3
- Effect of eicosapentaenoic acid, an omega-3 polyunsaturated fatty acid, on UVR-related cancer risk in humans. An assessment of early genotoxic markers.
Rhodes LE; Shahbakhti H; Azurdia RM; Moison RM; Steenwinkel MJ; Homburg MI; Dean MP; McArdle F; Beijersbergen van Henegouwen GM; Epe B; Vink AA · Carcinogenesis · 2003
Randomized trial42 participantsflagSkin Health forscienceOmega-3
- Randomized controlled trial using vitamins E and D supplementation in atopic dermatitis.
Javanbakht MH; Keshavarz SA; Djalali M; Siassi F; Eshraghian MR; Firooz A; Seirafi H; Ehsani AH; Chamari M; Mirshafiey A · The Journal of dermatological treatment · 2011
Randomized trial45 participantsflagSkin Health forscienceVitamin E
- Serum vitamin E levels and chronic inflammatory skin diseases: A systematic review and meta-analysis.
Liu X; Yang G; Luo M; Lan Q; Shi X; Deng H; Wang N; Xu X; Zhang C · PloS one · 2022
Meta-analysis20 studies pooledflagSkin Health forscienceVitamin E
- Evidence-Based Nutritional Interventions in Wound Care.
Saeg F; Orazi R; Bowers GM; Janis JE · Plastic and reconstructive surgery · 2021
Systematic review2,339 participants36 studies pooledflagSkin Health forscienceVitamin E
- Effects of tocotrienol on aging skin: A systematic review.
Ghazali NI; Mohd Rais RZ; Makpol S; Chin KY; Yap WN; Goon JA · Frontiers in pharmacology · 2022
Systematic reviewflagSkin Health forscienceVitamin E
- Carotenoids and carotenoids plus vitamin E protect against ultraviolet light-induced erythema in humans.
Stahl W; Heinrich U; Jungmann H; Sies H; Tronnier H · The American journal of clinical nutrition · 2000
Randomized trialflagSkin Health forscienceVitamin E
- Dietary supplementation with docosahexaenoic acid rich fish oil increases circulating levels of testosterone in overweight and obese men.
Abbott K; Burrows TL; Acharya S; Thota RN; Garg ML · Prostaglandins, leukotrienes, and essential fatty acids · 2021
Randomized trial61 participantsflagTestosterone Support forscienceFish Oil
- Fish oil produces an atherogenic lipid profile in hypertensive men.
Hughes GS; Ringer TV; Watts KC; DeLoof MJ; Francom SF; Spillers CR · Atherosclerosis · 1991
Randomized trial26 participantsflagTestosterone Support forscienceFish Oil
- Associations of Fish Oil Supplement Use With Testicular Function in Young Men.
Jensen TK; Priskorn L; Holmboe SA; Nassan FL; Andersson AM; Dalgård C; Petersen JH; Chavarro JE; Jørgensen N · JAMA network open · 2020
Cross-sectional study1,679 participantsflagTestosterone Support forscienceFish Oil
- Effect of Two Different Doses of Vitamin D Supplementation on Metabolic Profiles of Insulin-Resistant Patients with Polycystic Ovary Syndrome.
Jamilian M; Foroozanfard F; Rahmani E; Talebi M; Bahmani F; Asemi Z · Nutrients · 2018
Randomized trial90 participantsflagTestosterone Support forscienceVitamin D
- Androgens and hirsutism score of overweight women with polycystic ovary syndrome improved after vitamin D treatment: A randomized placebo controlled clinical trial.
Al-Bayyari N; Al-Domi H; Zayed F; Hailat R; Eaton A · Clinical nutrition (Edinburgh, Scotland) · 2021
Randomized trial60 participantsflagTestosterone Support forscienceVitamin D
- Association between plasma 25-OH vitamin D and testosterone levels in men.
Nimptsch K; Platz EA; Willett WC; Giovannucci E · Clinical endocrinology · 2012
Case-control study1,362 participantsflagTestosterone Support forscienceVitamin D
- Causal Link Between Vitamin D and Total Testosterone in Men: A Mendelian Randomization Analysis.
Chen C; Zhai H; Cheng J; Weng P; Chen Y; Li Q; Wang C; Xia F; Wang N; Lu Y · The Journal of clinical endocrinology and metabolism · 2020
Other4,254 participantsflagTestosterone Support forscienceVitamin D
- Associations of vitamin D status and vitamin D-related polymorphisms with sex hormones in older men.
Rafiq R; van Schoor NM; Sohl E; Zillikens MC; Oosterwerff MM; Schaap L; Lips P; de Jongh RT · The Journal of steroid biochemistry and molecular biology · 2017
Cohort study643 participantsflagTestosterone Support forscienceVitamin D
- Antioxidant vitamin and mineral supplements for preventing age-related macular degeneration.
Evans JR; Lawrenson JG · The Cochrane database of systematic reviews · 2018
Meta-analysis55,614 participants4 studies pooledflagVision Support forscienceVitamin E
- Dietary n-3 Fatty Acid, α-Tocopherol, Zinc, vitamin D, vitamin C, and β-carotene are Associated with Age-Related Macular Degeneration in Japan.
Aoki A; Inoue M; Nguyen E; Obata R; Kadonosono K; Shinkai S; Hashimoto H; Sasaki S; Yanagi Y · Scientific reports · 2017
Case-control study530 participantsflagVision Support forscienceVitamin E
- Dietary carotenoids, vitamins C and E, and risk of cataract in women: a prospective study.
Christen WG; Liu S; Glynn RJ; Gaziano JM; Buring JE · Archives of ophthalmology (Chicago, Ill. : 1960) · 2008
Cohort study35,551 participantsflagVision Support forscienceVitamin E
- Long-term nutrient intake and 5-year change in nuclear lens opacities.
Jacques PF; Taylor A; Moeller S; Hankinson SE; Rogers G; Tung W; Ludovico J; Willett WC; Chylack LT · Archives of ophthalmology (Chicago, Ill. : 1960) · 2005
Cohort study408 participantsflagVision Support forscienceVitamin E
- Dietary intake of antioxidants and risk of age-related macular degeneration.
van Leeuwen R; Boekhoorn S; Vingerling JR; Witteman JC; Klaver CC; Hofman A; de Jong PT · JAMA · 2005
Cohort study4,765 participantsflagVision Support forscienceVitamin E