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NeuroMag

Designs for Health
4.8
★ ★ ★ ★ ★
(203 ratings)
Magnesium 144 mg
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Score75
Clearly dosed Magtein suits users specifically seeking magnesium L-threonate. Modest elemental magnesium, three capsules, and very high cost make it weak for general repletion or value.
How scoring works
Quantity:90 Capsule(s) • (30 servings)
Goals:
Testosterone Support
General Health
Stress Relief
Energy
Cardiovascular Support
Heart Health

Score 75

Clearly dosed Magtein suits users specifically seeking magnesium L-threonate. Modest elemental magnesium, three capsules, and very high cost make it weak for general repletion or value.
How scoring works
$72.49($2.41 per serving)
iHerb
$ 72.49
Pure Formulas
$ 72.49
iHerb
$ 72.49
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Analysis

The three-capsule serving uses 2,000 mg of Magtein magnesium L-threonate to provide 144 mg of elemental magnesium. The raw material and elemental figures are both clear, avoiding a common dose-labeling confusion.

L-threonate is a specialized form, but the elemental amount is modest for users mainly trying to fill a broad magnesium gap. The general heart, bone, digestive, and energy goals are less directly served than a form-specific use case.

Thirty servings and a three-capsule dose make routine use less convenient. The very high serving cost means buyers are paying for the specific branded form rather than magnesium quantity.

Who is it for
  • Adults specifically seeking Magtein L-threonate
  • Users prioritizing form over elemental amount
  • People comfortable with a premium three-capsule serving
Best for
  • Branded magnesium L-threonate
  • A specialized magnesium form
  • Clear raw-material and elemental dosing

Pros

  • Uses branded Magtein
  • Clearly states 144 mg elemental magnesium
  • Avoids an ambiguous proprietary blend
  • Provides a specialized form

Cons

  • Provides modest elemental magnesium
  • Requires three capsules
  • Offers only 30 servings
  • Has very poor serving value

Warnings

  • The 144 mg magnesium serving may cause diarrhea, cramping, or nausea, especially when taken at once.
  • Reduced kidney function can impair magnesium clearance, so regular supplemental use requires medical guidance in that situation.
  • Magnesium can reduce absorption of levothyroxine, bisphosphonates, and certain antibiotics; follow the medicine-specific spacing interval.

Nutrient quality

92 Highest impact

Form quality is favorable and the magnesium amount is meaningful. The focused ingredient profile remains aligned with its intended use.

.

Ingredient transparency

81 Highest impact

The elemental amount is clearly stated without a hidden key dose. Complete directions and inactive ingredients are not supplied.

.

Customer satisfaction

66 High impact

The average customer rating is very strong. The rating base is adequate but not especially deep, while specific review experiences were not supplied.

.

Value for money

54 Moderate impact

Serving economics are weak for the supplied amount. Form or label limitations keep value moderate.

.
Report analysis

Goals

Testosterone Support
Testosterone Support
Impact
Highest effect
A- Goal FitA Strength of SupportC CoverageA Formula Quality
Magnesium · 2000 mg

Magnesium provides a relevant route to testosterone support. The disclosed amount appears meaningful for that focused role.

The formula remains narrow rather than comprehensive. The large magnesium amount may cause diarrhea, cramping, and fluid loss, especially because an oxide form is present.

Study evidence
Magnesium Disputed 5 studies
General Health
General Health
Impact
Highest effect
B+ Goal FitA Strength of SupportC CoverageA Formula Quality
Magnesium · 2000 mg

Branded magnesium L-threonate provides focused magnesium support with unusually clear raw-material and elemental disclosure. Its form may appeal to users prioritizing nervous-system delivery over a larger elemental magnesium amount.

The formula is narrow and supplies less elemental magnesium than many general-purpose products. Its premium format may be difficult to justify for users who only want routine magnesium repletion.

Study evidence
Magnesium Supportive 114 studies
Stress Relief
Stress Relief
Impact
Highest effect
B- Goal FitA Strength of SupportC CoverageA+ Formula Quality
Magnesium · 2000 mg

Patented magnesium L-threonate provides a well-defined form intended to deliver magnesium to the nervous system. The disclosed elemental amount matches the typical serving for this specialized material.

Evidence is more developed for cognitive support than for direct relief of perceived stress, so the goal fit is narrower than with leading calming actives. The formula remains focused and free of distracting add-ons.

Study evidence
Magnesium Supportive 13 studies
Energy
Energy
Impact
High effect
B+ Goal FitA- Strength of SupportC- CoverageA Formula Quality
Magnesium · 2000 mg

Magnesium contributes to cellular energy, muscle function, and normal nerve signaling. Magtein supplies a patented magnesium L-threonate form with precise elemental disclosure.

The 144 mg magnesium amount matches the studied L-threonate serving but provides less elemental magnesium than common general-purpose products. Its specialized form offers focused depth rather than broad foundational coverage.

Study evidence
Magnesium Supportive 4 studies
Cardiovascular Support
Cardiovascular Support
Impact
High effect
C Goal FitB Strength of SupportF CoverageA Formula Quality
Magnesium · 2000 mg

Magnesium supports normal vascular and cardiac function, but the amount is moderate rather than robust. Magnesium L-threonate is designed mainly for nervous-system delivery and has less direct cardiovascular evidence than common glycinate or citrate forms.

The branded source and exact elemental yield are clearly disclosed. A focused formula avoids padding but leaves every other major heart-health pathway uncovered.

Study evidence
Magnesium Supportive 123 studies
Heart Health
Heart Health
Impact
High effect
C Goal FitB Strength of SupportF CoverageA Formula Quality
Magnesium · 2000 mg

Magnesium supports normal vascular and cardiac function, but the amount is moderate rather than robust. Magnesium L-threonate is designed mainly for nervous-system delivery and has less direct cardiovascular evidence than common glycinate or citrate forms.

The branded source and exact elemental yield are clearly disclosed. A focused formula avoids padding but leaves every other major heart-health pathway uncovered.

Study evidence
Magnesium Supportive 158 studies

Ingredients

IngredientAmount per serving
Magnesium (Magnesium L-Threonate)
 144 mg
Magtein(TM) (Magnesium L-Threonate)
 2000 mg
Gluten Free Adults 18–50
Report overview
Magnesium (Magnesium L-Threonate) · 144 mg OverallScore90
A+ Active Ingredient Quality & BioavailabilityA Dose, Safety & Label TransparencyB- Value

The patented L-threonate form offers strong absorption potential and a validated raw material. The elemental amount is clearly disclosed at the studied L-threonate level. The focused formula lacks added cofactors, while the patented material partly justifies its premium cost.

View ingredientView products
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85 Performance

Magnesium Bisglycinate Chelate

Healthy Origins
<p>Its label clearly provides 200 mg of Magnesium as TRAACS Magnesium Bisglycinate Chelate, making it a more clearly defined magnesium option. Compared with the original, its ingredient and goal alignment is stronger, although the input does not provide independent testing or absorption evidence.</p>
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Albion Chelated Magnesium Glycinate

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<p>Its label clearly provides 400 mg of Magnesium as TRAACS Magnesium Bisglycinate Chelate, making it a more clearly defined magnesium option. Compared with the original, its ingredient and goal alignment is stronger, although the input does not provide independent testing or absorption evidence.</p>
80 Performance

Magnesium Glycinate Chelate

Designs for Health
<p>Its label clearly provides 300 mg of Magnesium as TRAACS Magnesium Glycinate Chelate buffered, making it a more clearly defined magnesium option. Compared with the original, its ingredient and goal alignment is stronger, although the input does not provide independent testing or absorption evidence.</p>
91 Budget

Krebs Magnesium Potassium Complex

Nature's Way
<p>Its label clearly provides 250 mg of Magnesium as Magnesium Lysinate, preserving relevant magnesium coverage. Compared with the original, it lowers the serving cost, although the input does not provide independent testing or absorption evidence.</p>
88 Budget

Magnesium Bisglycinate Powder

NOW
<p>Its label clearly provides 250 mg of Magnesium as Magnesium Bisglycinate, preserving relevant magnesium coverage. Compared with the original, it lowers the serving cost, although the input does not provide independent testing or absorption evidence.</p>
80 Budget

Magnesium Caps 500 mg

Life Extension
<p>Its label clearly provides 500 mg of Magnesium as Magnesium Citrate, preserving relevant magnesium coverage. Compared with the original, it lowers the serving cost, although the input does not provide independent testing or absorption evidence.</p>
84 Value

Magnesium Bisglycinate Chelate

Healthy Origins
<p>Its label clearly provides 200 mg of Magnesium as TRAACS Magnesium Bisglycinate Chelate, keeping the formula relevant to magnesium. Compared with the original, the lower serving cost and ingredient detail create a useful quality-to-cost balance, although the input does not provide independent testing or absorption evidence.</p>
84 Value

Magnesium Glycinate

NOW
<p>Its label clearly provides 200 mg of Magnesium, keeping the formula relevant to magnesium. Compared with the original, the lower serving cost and ingredient detail create a useful quality-to-cost balance, although the input does not provide independent testing or absorption evidence.</p>
81 Value

Ultra-Mag

Source Naturals
<p>Its label clearly provides 30 mg of Vitamin B6 as Pyridoxine Hydrochloride, keeping the formula relevant to magnesium. Compared with the original, the lower serving cost and ingredient detail create a useful quality-to-cost balance, although the input does not provide independent testing or absorption evidence.</p>
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Magnesium-L-threonate improves sleep quality and daytime functioning in adults with self-reported sleep problems: A randomized controlled trial.
    Hausenblas HA; Lynch T; Hooper S; Shrestha A; Rosendale D; Gu J · Sleep medicine: X · 2025
    Randomized trial80 participantsEnergy forMagnesium
  2. Exercise, magnesium and immune function.
    Laires MJ; Monteiro C · Magnesium research · 2008
    Narrative reviewEnergy forMagnesium
  3. Quantitative Association Between Serum/Dietary Magnesium and Cardiovascular Disease/Coronary Heart Disease Risk: A Dose-Response Meta-analysis of Prospective Cohort Studies.
    Zhao L; Hu M; Yang L; Xu H; Song W; Qian Y; Zhao M · Journal of cardiovascular pharmacology · 2020
    Meta-analysis544,581 participants18 studies pooledHeart Health Cardiovascular Support forMagnesium
  4. Effects of long-term magnesium supplementation on endothelial function and cardiometabolic risk markers: A randomized controlled trial in overweight/obese adults.
    Joris PJ; Plat J; Bakker SJ; Mensink RP · Scientific reports · 2018
    Randomized trial52 participantsHeart Health forMagnesium
  5. An update on magnesium and bone health.
    Rondanelli M; Faliva MA; Tartara A; Gasparri C; Perna S; Infantino V; Riva A; Petrangolini G; Peroni G · Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2022
    Narrative reviewBone Health forMagnesium
  6. Magnesium intake, bone mineral density, and fractures: results from the Women's Health Initiative Observational Study.
    Orchard TS; Larson JC; Alghothani N; Bout-Tabaku S; Cauley JA; Chen Z; LaCroix AZ; Wactawski-Wende J; Jackson RD · The American journal of clinical nutrition · 2014
    Cohort study73,684 participantsBone Health forMagnesium
  7. A Randomized Double-blind Placebo-controlled Trial on the Effect of Magnesium Oxide in Patients With Chronic Constipation.
    Mori S; Tomita T; Fujimura K; Asano H; Ogawa T; Yamasaki T; Kondo T; Kono T; Tozawa K; Oshima T; Fukui H; Kimura T; Watari J; Miwa H · Journal of neurogastroenterology and motility · 2022
    Randomized trial34 participantsDigestive Health forMagnesium
  8. Diagnosis of magnesium-induced diarrhea.
    Fine KD; Santa Ana CA; Fordtran JS · The New England journal of medicine · 1991
    Clinical trial19 participantsDigestive Health forMagnesium
  9. Association between Serum Magnesium and Fractures: A Systematic Review and Meta-Analysis of Observational Studies.
    Dominguez LJ; Veronese N; Ciriminna S; Pérez-Albela JL; Vásquez-López VF; Rodas-Regalado S; Di Bella G; Parisi A; Tagliaferri F; Barbagallo M · Nutrients · 2023
    Meta-analysis119,755 participants4 studies pooledBone Health forMagnesium
  10. Bioabsorbable Magnesium-Based Materials Potential and Safety in Bone Surgery: A Systematic Review.
    Hung CH; Kwok YC; Yip J; Wong HH; Leung YY · Craniomaxillofacial trauma & reconstruction · 2025
    Systematic review386 participants8 studies pooledBone Health forMagnesium
  11. Vascularized bone grafting fixed by biodegradable magnesium screw for treating osteonecrosis of the femoral head.
    Zhao D; Huang S; Lu F; Wang B; Yang L; Qin L; Yang K; Li Y; Li W; Wang W; Tian S; Zhang X; Gao W; Wang Z; Zhang Y; Xie X; Wang J; Li J · Biomaterials · 2016
    Randomized trial48 participantsBone Health forMagnesium
  12. Sex-specific differences in the association of magnesium intake with femoral neck bone mineral density among older adults.
    Wang B; Tan X; Yao X; Zhu Z · Endocrine connections · 2025
    Cross-sectional study1,343 participantsBone Health forMagnesium
  13. Circulating and dietary magnesium and risk of cardiovascular disease: a systematic review and meta-analysis of prospective studies.
    Del Gobbo LC; Imamura F; Wu JH; de Oliveira Otto MC; Chiuve SE; Mozaffarian D · The American journal of clinical nutrition · 2013
    Meta-analysis313,041 participants16 studies pooledCardiovascular Support forMagnesium
  14. Magnesium and the risk of cardiovascular events: a meta-analysis of prospective cohort studies.
    Qu X; Jin F; Hao Y; Li H; Tang T; Wang H; Yan W; Dai K · PloS one · 2013
    Meta-analysis532,979 participants19 studies pooledCardiovascular Support forMagnesium
  15. Comparative Efficacy of Nutraceuticals on Endothelial Function: A Systematic Review and Network Meta-Analysis.
    Norouzzadeh M; Rashedi MH; Mahdavi-Mazdeh G; Kosari A; Shahinfar H · Current atherosclerosis reports · 2026
    Meta-analysisCardiovascular Support Heart Health forMagnesium
  16. Serum magnesium, mortality, and cardiovascular disease in chronic kidney disease and end-stage renal disease patients: a systematic review and meta-analysis.
    Xiong J; He T; Wang M; Nie L; Zhang Y; Wang Y; Huang Y; Feng B; Zhang J; Zhao J · Journal of nephrology · 2020
    Meta-analysis200,934 participants20 studies pooledCardiovascular Support forMagnesium
  17. Efficacy of oral magnesium therapy in the treatment of chronic constipation in spastic cerebral palsy children: a randomized controlled trial.
    Hassanein SMA; Deifallah SM; Bastawy HA · World journal of pediatrics : WJP · 2021
    Randomized trial100 participantsDigestive Health forMagnesium
  18. Ca:Mg ratio, medium-chain fatty acids, and the gut microbiome.
    Fan L; Zhu X; Sun S; Yu C; Huang X; Ness R; Dugan LL; Shu L; Seidner DL; Murff HJ; Fodor AA; Azcarate-Peril MA; Shrubsole MJ; Dai Q · Clinical nutrition (Edinburgh, Scotland) · 2022
    Randomized trial240 participantsDigestive Health forMagnesium
  19. The Magnesium-Rich Formula for Functional Constipation in Infants: a Randomized Comparator-Controlled Study.
    Benninga MA; MENA Infant Constipation Study Group; Vandenplas Y · Pediatric gastroenterology, hepatology & nutrition · 2022
    Randomized trial286 participantsDigestive Health forMagnesium
  20. Magnesium treatment increases gut microbiome synthesizing vitamin D and inhibiting colorectal cancer: results from a double-blind precision-based randomized placebo-controlled trial.
    Sun E; Zhu X; Ness RM; Murff HJ; Sun S; Yu C; Fan L; Azcarate-Peril MA; Shrubsole MJ; Dai Q · The American journal of clinical nutrition · 2025
    Randomized trial240 participantsDigestive Health forMagnesium
  21. Total magnesium intake and risk of frailty in older women.
    Struijk EA; Fung TT; Bischoff-Ferrari HA; Willett WC; Lopez-Garcia E · Journal of cachexia, sarcopenia and muscle · 2024
    Cohort study81,524 participantsEnergy forMagnesium
  22. Red blood cell magnesium and chronic fatigue syndrome.
    Cox IM; Campbell MJ; Dowson D · Lancet (London, England) · 1991
    Randomized trial32 participantsEnergy forMagnesium
  23. Perioperative systemic magnesium to minimize postoperative pain: a meta-analysis of randomized controlled trials.
    De Oliveira GS; Castro-Alves LJ; Khan JH; McCarthy RJ · Anesthesiology · 2013
    Meta-analysis1,257 participants20 studies pooledGeneral Health forMagnesium
  24. Long-term outcome after intravenous magnesium sulphate in suspected acute myocardial infarction: the second Leicester Intravenous Magnesium Intervention Trial (LIMIT-2).
    Woods KL; Fletcher S · Lancet (London, England) · 1994
    Randomized trial2,316 participantsGeneral Health forMagnesium
  25. Association of magnesium sulfate use with mortality in critically ill patients with sepsis: a retrospective propensity score-matched cohort study.
    Gu WJ; Duan XJ; Liu XZ; Cen Y; Tao LY; Lyu J; Yin HY · British journal of anaesthesia · 2023
    Cohort study10,999 participantsGeneral Health forMagnesium
  26. Hypomagnesemia and Mortality in Incident Hemodialysis Patients.
    Li L; Streja E; Rhee CM; Mehrotra R; Soohoo M; Brunelli SM; Kovesdy CP; Kalantar-Zadeh K · American journal of kidney diseases : the official journal of the National Kidney Foundation · 2016
    Cohort study9,359 participantsGeneral Health forMagnesium
  27. The effects of magnesium supplementation on abnormal uterine bleeding, alopecia, quality of life, and acne in women with polycystic ovary syndrome: a randomized clinical trial.
    Jaripur M; Ghasemi-Tehrani H; Askari G; Gholizadeh-Moghaddam M; Clark CCT; Rouhani MH · Reproductive biology and endocrinology : RB&E · 2022
    Randomized trial64 participantsGeneral Health forMagnesium
  28. Effects of magnesium supplementation on improving hyperglycemia, hypercholesterolemia, and hypertension in type 2 diabetes: A pooled analysis of 24 randomized controlled trials.
    Xu L; Li X; Wang X; Xu M · Frontiers in nutrition · 2023
    Meta-analysis1,325 participants24 studies pooledHeart Health forMagnesium
  29. The effect of lowering blood pressure by magnesium supplementation in diabetic hypertensive adults with low serum magnesium levels: a randomized, double-blind, placebo-controlled clinical trial.
    Guerrero-Romero F; Rodríguez-Morán M · Journal of human hypertension · 2009
    Randomized trial82 participantsHeart Health forMagnesium
  30. Positive effects of magnesium supplementation in metabolic syndrome.
    Kisters S; Kisters K; Werner T; Vormann J; Tokmak F; Westhoff T; Gröber U; Predel HG; Reuter H · International journal of clinical pharmacology and therapeutics · 2024
    Randomized trial54 participantsHeart Health forMagnesium
  31. Role of magnesium supplementation in the treatment of depression: A randomized clinical trial.
    Tarleton EK; Littenberg B; MacLean CD; Kennedy AG; Daley C · PloS one · 2017
    Randomized trial126 participantsStress Relief forMagnesium
  32. Effects of Intravenous Esketamine or Magnesium Sulfate on Early Postoperative Negative Emotions and Pain in Patients Undergoing Endoscopic Sinus Surgery: A Randomized Controlled Trial.
    Wang L; Zhou J; Liu Q; Qian K; Wang L; Xie C · Therapeutics and clinical risk management · 2026
    Randomized trial137 participantsStress Relief forMagnesium
  33. Effect of short-term magnesium supplementation on anxiety, depression and sleep quality in patients after open-heart surgery.
    Saba S; Faizi F; Sepandi M; Nehrir B · Magnesium research · 2022
    Non-randomized trial60 participantsStress Relief forMagnesium
  34. Effects of dry needling compared to magnesium infiltration in trigger points for patients with myofascial pain syndrome: a randomized controlled study in Tunisia.
    Dhouibi J; Moncer R; Kalbousi N; Gaddour M; Laayouni S; Ouanes W; Kacem B; Jemni S · Korean journal of family medicine · 2026
    Randomized trial45 participantsStress Relief forMagnesium
  35. Effect of magnesium and vitamin B6 supplementation on mental health and quality of life in stressed healthy adults: Post-hoc analysis of a randomised controlled trial.
    Noah L; Dye L; Bois De Fer B; Mazur A; Pickering G; Pouteau E · Stress and health : journal of the International Society for the Investigation of Stress · 2021
    Randomized trialStress Relief forMagnesium
  36. Magnesium and anabolic hormones in older men.
    Maggio M; Ceda GP; Lauretani F; Cattabiani C; Avantaggiato E; Morganti S; Ablondi F; Bandinelli S; Dominguez LJ; Barbagallo M; Paolisso G; Semba RD; Ferrucci L · International journal of andrology · 2012
    Cohort study399 participantsTestosterone Support forMagnesium
  37. Analysis of the relationship between the blood concentration of several metals, macro- and micronutrients and endocrine disorders associated with male aging.
    Rotter I; Kosik-Bogacka DI; Dołęgowska B; Safranow K; Kuczyńska M; Laszczyńska M · Environmental geochemistry and health · 2017
    Cross-sectional study313 participantsTestosterone Support forMagnesium
  38. Effect of magnesium supplementation in improving hyperandrogenism, hirsutism, and sleep quality in women with polycystic ovary syndrome: A randomized, placebo-controlled clinical trial.
    Gholizadeh-Moghaddam M; Ghasemi-Tehrani H; Askari G; Jaripur M; Clark CCT; Rouhani MH · Health science reports · 2024
    Randomized trial64 participantsTestosterone Support forMagnesium
  39. The effects of trace element supplementation on glycolipid metabolism in PCOS: a systematic review and meta-analysis.
    Yang L; Gao Y; Zhao W; Qi Y; Duo X; Wang H · Frontiers in nutrition · 2025
    Meta-analysis1,600 participants25 studies pooledTestosterone Support forMagnesium
  40. Effects of magnesium supplementation on testosterone levels of athletes and sedentary subjects at rest and after exhaustion.
    Cinar V; Polat Y; Baltaci AK; Mogulkoc R · Biological trace element research · 2011
    Non-randomized trial20 participantsTestosterone Support forMagnesium