Life Extension Mix Powder

Life Extension Mix Powder

Life Extension4.4 (733 ratings)
Format:Powder Quantity: 360 Gram(s) · 30 servings
Goals

Product analysis

44 out of 100

Life Extension Mix Powder offers broad nutritional support for normal energy use, immunity and bone maintenance when diet falls short. Unnamed blend components and missing proportions make it harder to judge the contribution of its many extras.

AI assessment of the formula, label and price. How scoring works

Nutrient Quality42

Some vitamins and minerals use favorable forms, including iodine and zinc. Unknown blend proportions and incomplete form details limit a clear judgment of the whole mixture.

Ingredient Transparency71

Ingredient amounts and many forms are stated, helping you identify much of the formula. Missing mixture proportions and unnamed blend components prevent precise comparison.

Value For Money34

The broad formula is relatively costly for many of its individual nutrients. Vitamin B6 is better value within the mix, but several botanical contributions remain difficult to judge.

Customer Satisfaction73

Customer feedback is generally positive across several hundred ratings. That gives a useful picture of satisfaction without showing which ingredients provide a benefit.

Product Focus0

The extensive ingredient list spreads across many health aims rather than one clear purpose. Its strongest practical role is filling nutritional gaps, with uncertain added benefit from many extras.

Format
Powder
Container
360 Gram(s)
Per serving
$1.80
Customer rating
4.4 · 733 ratings
Report analysis

Goals

Impact
Moderate effect
F Ingredient FitD PathwaysA EvidenceA+ Formulation Logic
Folate · 400 mcg DFEVitamin B12 · 600 mcgVitamin B6 · 105 mgMolybdenum · 125 mcgSelenium · 200 mcgMagnesium · 420 mgVitamin E · 60 mgZinc · 35 mgVitamin C · 970 mgTaurine · 200 mgRiboflavin · 50 mg

Folate, B12 and B6 support methyl-group metabolism, while riboflavin contributes to coenzyme function and selenium supports antioxidant systems. The many other ingredients make the connection to this goal broad and mainly nutritional; NAC and taurine add related mechanisms without establishing routine toxin removal.

How this product is rated for Liver & Detox

Ingredient fit40

8 ingredients relate to this goal, alongside 32 actives aimed at other needs. The relevant amounts provide partial support in the saved comparison; some are modest or unclear.
Goal fit
8 ingredients relate to this goal, alongside 32 actives aimed at other needs.
Dose adequacy
The relevant amounts provide partial support in the saved comparison; some are modest or unclear.

Pathways49

Methyl-group supply is the strongest mechanism in the saved assessment, with substantial coverage. 1 of the three target mechanisms meets the saved coverage level.
Depth
Methyl-group supply is the strongest mechanism in the saved assessment, with substantial coverage.
Breadth
1 of the three target mechanisms meets the saved coverage level.

Evidence91

Magnesium provides the strongest evidence contribution among the assessed amounts. This remains specific to the supplied evidence and its context.
Evidence strength
Magnesium provides the strongest evidence contribution among the assessed amounts. This remains specific to the supplied evidence and its context.
Studied preparation
Most of the assessed contribution matches preparations recognized in the saved assessment; Molybdenum, Vitamin B2 (Riboflavin), Vitamin B6 does not.

Formulation logic100

All 8 assessed ingredients meet the saved amount threshold. No conflict was recorded by the supplied checks.
Partner coverage
The assessed ingredients can work alone or have their required partners present.
Conflicts
No conflict was recorded by the supplied checks.
Effective doses
All 8 assessed ingredients meet the saved amount threshold.
Study evidence
Folate Supportive 16 studies
Green Tea Disputed 16 studies
Magnesium Supportive 19 studies
Selenium Supportive 10 studies
Taurine Supportive 2 studies
Vitamin C Supportive 9 studies
Vitamin E Supportive 23 studies
Zinc Supportive 30 studies
Impact
High effect
D+ Ingredient FitA+ PathwaysA- EvidenceA+ Formulation Logic
Folate · 400 mcg DFEVitamin B12 · 600 mcgVitamin D · 50 mcgMagnesium · 420 mgBoron · 3 mgSelenium · 200 mcgTaurine · 200 mgAshwagandha · 125 mgZinc · 35 mgVitamin C · 970 mg

B vitamins contribute nutrients used in normal energy metabolism; folate and B12 contribute to blood formation and one-carbon metabolism. Magnesium contributes to normal energy and mineral metabolism. Vitamin D contributes to normal bone and mineral metabolism. Vitamin C, Zinc and Selenium provide nutrients involved in normal antioxidant or immune functions. Iodine contributes to thyroid nutrient needs when intake is low. These nutritional contributions matter most when intake falls short; extra benefit with adequate intake is not established.

How this product is rated for Everyday Health

Ingredient fit52

The main relevant ingredients are Vitamin B1 (Thiamin), Vitamin B2 (Riboflavin), Vitamin B3 (Niacin), Vitamin B5 (Pantothenic Acid), Magnesium, Vitamin B9 (Folate), Vitamin B12, Vitamin B6, Vitamin D, Vitamin C, Zinc, Selenium and Iodine. Their value is nutritional, rather than a demonstrated broad health improvement.
Goal fit
The nutrient core fits several routine nutritional needs, while additional actives and links to other goals make the formula less focused.
Dose adequacy
The selected serving provides several meaningful nutrient amounts, although contributions vary across ingredients.

Pathways100

The main areas represented are energy metabolism cofactors, one-carbon metabolism and blood formation, antioxidant and immune defence.
Depth
The strongest supported area is energy metabolism cofactors, through the relevant nutrients.
Breadth
The main areas represented are energy metabolism cofactors, one-carbon metabolism and blood formation, antioxidant and immune defence.

Evidence86

Magnesium supports a nutritional role, chiefly when intake is low; this does not establish extra benefit with adequate intake.
Evidence strength
Magnesium supports a nutritional role, chiefly when intake is low; this does not establish extra benefit with adequate intake.
Studied preparation
The relevant nutrient preparations were accepted in the saved comparison; no superior form or delivery benefit is established.

Formulation logic100

The relevant ingredients can contribute independently or have their required partner; their combination does not establish added benefit. No conflict was identified by the evaluated checks.
Partner coverage
The relevant ingredients can contribute independently or have their required partner; their combination does not establish added benefit.
Conflicts
No conflict was identified by the evaluated checks.
Effective doses
The counted ingredients reach the comparison’s minimum amount criterion; this is not proof of a clinical benefit.
Study evidence
Boron Supportive 6 studies
Bromelain Supportive 11 studies
Folate Supportive 80 studies
Magnesium Supportive 114 studies
Selenium Supportive 70 studies
Taurine No effect 3 studies
Vitamin C Supportive 56 studies
Vitamin D Supportive 115 studies
Zinc Supportive 60 studies
Heart Health
Impact
Moderate effect
D- Ingredient FitC PathwaysA- EvidenceA+ Formulation Logic
Magnesium · 420 mgVitamin B12 · 600 mcgVitamin B6 · 105 mgTaurine · 200 mgGreen Tea · 325 mgFolate · 400 mcg DFEVitamin D · 50 mcg

Folate, vitamin B6 and vitamin B12 support normal homocysteine metabolism, but changes in this marker do not reliably predict fewer heart events. Thiamin and selenium mainly contribute by helping meet nutritional needs, with little reason to expect added heart benefit once needs are met.

Magnesium at 140 mg adds limited blood-vessel support. Taurine and grape-seed extract are present at small amounts relative to the supplied trial exposures, and green-tea findings depend on the specific preparation.

How this product is rated for Heart Health

Ingredient fit40

Heart-related ingredients sit alongside ingredients aimed at other health goals. The assessed amounts provide partial and uneven coverage of the saved comparison references.
Goal fit
Heart-related ingredients sit alongside ingredients aimed at other health goals.
Dose adequacy
The assessed amounts provide partial and uneven coverage of the saved comparison references.

Pathways60

The strongest assessed connection is to homocysteine metabolism, a marker-related function rather than a demonstrated reduction in heart events. One heart-related process has meaningful coverage, with limited coverage elsewhere.
Depth
The strongest assessed connection is to homocysteine metabolism, a marker-related function rather than a demonstrated reduction in heart events.
Breadth
One heart-related process has meaningful coverage, with limited coverage elsewhere.

Evidence89

Magnesium provides the strongest evidence contribution among the assessed ingredients, within the supplied evidence's limits. The assessed ingredients match the preparation categories used in the saved review.
Evidence strength
Magnesium provides the strongest evidence contribution among the assessed ingredients, within the supplied evidence's limits.
Studied preparation
The assessed ingredients match the preparation categories used in the saved review.

Formulation logic96

The assessed ingredients can contribute individually or have their required companion present. No configured ingredient conflict was identified in the supplied assessment. Quercetin falls below the saved minimum amount threshold.
Partner coverage
The assessed ingredients can contribute individually or have their required companion present.
Conflicts
No configured ingredient conflict was identified in the supplied assessment.
Effective doses
Quercetin falls below the saved minimum amount threshold.
Study evidence
Folate Supportive 116 studies
Green Tea Supportive 84 studies
Magnesium Supportive 158 studies
Niacin Supportive 105 studies
Potassium Supportive 182 studies
Selenium Mixed 89 studies
Taurine Supportive 25 studies
Vitamin B6 Supportive 44 studies
Vitamin D Mixed 164 studies
Impact
Moderate effect
F Ingredient FitF PathwaysA EvidenceA+ Formulation Logic
Vitamin D · 50 mcgVitamin E · 60 mgTaurine · 200 mgVitamin C · 970 mgGreen Tea · 325 mg

Getting enough zinc or magnesium may help when low nutrient levels contribute to low-grade inflammation. That conditional benefit does not imply that extra amounts reduce inflammation when you already get enough. Normal nutrient functions and changes in blood markers are also different from relief of symptoms or treatment of an inflammatory condition.

How this product is rated for Inflammation

Ingredient fit31

Getting enough zinc or magnesium may help when low nutrient levels contribute to low-grade inflammation.
Goal fit
Getting enough zinc or magnesium may help when low nutrient levels contribute to low-grade inflammation.
Dose adequacy
Quercetin: 5 mg per serving. An amount alone does not predict an increase in inflammatory symptom relief.

Pathways18

Getting enough zinc or magnesium may help when low nutrient levels contribute to low-grade inflammation.
Depth
Getting enough zinc or magnesium may help when low nutrient levels contribute to low-grade inflammation.
Breadth
Changes in inflammatory blood markers do not necessarily mean symptom relief or a broad health benefit.

Evidence93

Getting enough zinc or magnesium may help when low nutrient levels contribute to low-grade inflammation.
Evidence strength
Getting enough zinc or magnesium may help when low nutrient levels contribute to low-grade inflammation.
Studied preparation
The preparation matters: different forms and extracts cannot automatically share the same anti-inflammatory effects.

Formulation logic100

No particular ingredient conflict or missing required partner is identified.
Partner coverage
No missing required ingredient partner is identified.
Conflicts
No particular ingredient conflict is identified.
Effective doses
Quercetin: 5 mg per serving. This is a label-serving amount, not an inferred daily intake.
Study evidence
Apigenin No effect 1 study
Bromelain Supportive 12 studies
Luteolin Not classified

No linked studies yet.

Lycopene Supportive 15 studies
Magnesium Supportive 41 studies
Selenium Supportive 34 studies
Taurine Supportive 12 studies
Vitamin C Supportive 50 studies
Vitamin D Supportive 101 studies
Vitamin E Supportive 20 studies
Zinc Supportive 64 studies
Immunity
Impact
High effect
D- Ingredient FitB- PathwaysA+ EvidenceA+ Formulation Logic
Magnesium · 420 mgVitamin C · 970 mgZinc · 35 mgVitamin A · 1500 mcg RAEVitamin D · 50 mcgSelenium · 200 mcg

Zinc supports immune-cell function, while vitamin A helps maintain normal barriers. B vitamins and copper can help restore immune function when intake is deficient, and selenium supports antioxidant systems when intake is insufficient. These nutrient roles do not establish additional infection prevention when nutrition is adequate. Vitamin C also has limited regular-use cold-duration evidence; the unresolved elder declaration adds no confirmed contribution.

How this product is rated for Immunity

Ingredient fit41

Relevant nutrient amounts contribute, while the formula’s focus and serving quantities determine the saved ingredient finding.
Goal fit
Relevant ingredients sit within a broader formula containing ingredients directed at other goals.
Dose adequacy
The declared serving makes a partial contribution against the saved amount comparisons, which are not clinical benefit thresholds.

Pathways70

The strongest assigned area is oxidative and inflammatory balance. These ingredient associations do not establish how much infection risk changes.
Depth
The saved findings emphasize oxidative and inflammatory balance; this describes the assigned ingredient roles rather than proven protection against infection.
Breadth
Coverage is concentrated in two immune areas, with less support across the remaining areas.

Evidence100

The evidence supports bounded nutrient functions or preparation-specific findings, rather than a general promise of infection prevention.
Evidence strength
Vitamin C leads the saved evidence finding; its supported role does not establish general infection prevention.
Studied preparation
The saved preparation finding is complete for the included ingredients; it does not establish that this whole product reproduces a clinical regimen.

Formulation logic100

The included ingredients have no missing required partners or configured conflicts. Meeting the saved amount comparisons does not prove a combined clinical benefit.
Partner coverage
No missing required partner limits the included ingredients in the saved findings; this does not demonstrate an added benefit from combining them.
Conflicts
No configured ingredient conflict was identified. This finding does not establish overall safety or cover every possible interaction.
Effective doses
The included ingredients reach the saved minimum amount threshold; this threshold is not proof of a clinically effective immune dose.
Study evidence
Bromelain Not classified 1 study
Green Tea Not classified 2 studies
Magnesium Supportive 8 studies
Selenium Mixed 37 studies
Vitamin A Supportive 107 studies
Vitamin C Supportive 53 studies
Vitamin D Supportive 85 studies
Vitamin E Supportive 21 studies
Zinc Supportive 73 studies
Impact
Moderate effect
D Ingredient FitF PathwaysA EvidenceA+ Formulation Logic
Iodine · 150 mcgVitamin D · 50 mcgVitamin B5 · 600 mgMagnesium · 420 mgRiboflavin · 50 mgThiamin · 125 mgVitamin B12 · 600 mcgPotassium · 35 mg

B vitamins support normal energy metabolism, while folate, B12 and vitamin C may help with tiredness when a dietary shortfall is involved. Larger amounts do not by themselves provide extra energy once nutritional needs are met. Magnesium adds nutritional support, while the small ashwagandha amount has uncertain relevance to fatigue.

How this product is rated for Energy

Ingredient fit47

11 assessed ingredients relate to energy alongside 32 other active ingredients, giving the formula a broader focus. The assessed amounts meet part of the saved dose benchmarks.
Goal fit
11 assessed ingredients relate to energy alongside 32 other active ingredients, giving the formula a broader focus.
Dose adequacy
The assessed amounts meet part of the saved dose benchmarks.

Pathways0

The saved findings identify no coverage of the assessed alertness, muscle-energy, mitochondrial, stress-fatigue or circulation mechanisms. None of the three target areas reaches the saved threshold for substantial coverage.
Depth
The saved findings identify no coverage of the assessed alertness, muscle-energy, mitochondrial, stress-fatigue or circulation mechanisms.
Breadth
None of the three target areas reaches the saved threshold for substantial coverage.

Evidence95

Vitamin D provides the strongest saved evidence among ingredients meeting the amount benchmark. That finding does not establish extra energy from the whole formula. Preparation matching is incomplete for Iodine, limiting direct transfer of results from specific preparations.
Evidence strength
Vitamin D provides the strongest saved evidence among ingredients meeting the amount benchmark. That finding does not establish extra energy from the whole formula.
Studied preparation
Preparation matching is incomplete for Iodine, limiting direct transfer of results from specific preparations.

Formulation logic100

The assessed ingredients can act independently or have their required partner present. No configured ingredient conflicts were identified in the saved findings. 11 of 11 assessed ingredients meet the saved minimum amount benchmark.
Partner coverage
The assessed ingredients can act independently or have their required partner present.
Conflicts
No configured ingredient conflicts were identified in the saved findings.
Effective doses
11 of 11 assessed ingredients meet the saved minimum amount benchmark.
Study evidence
Iodine Adverse 3 studies
Magnesium Supportive 4 studies
Potassium Supportive 2 studies
Thiamin Disputed 12 studies
Vitamin D Supportive 32 studies

Ingredients

IngredientAmount per servingScore
Vitamin A (Beta-Carotene, Vitamin A Acetate)
1500 mcg RAE
Vitamin C (Acerola Extract, Ascorbic Acid, Ascorbyl Palmitate, Calcium Ascorbate, Magnesium Ascorbate, Niacinamide Ascorbate)
970 mg 58
Vitamin D3 (Cholecalciferol)
50 mcg
Vitamin E (D-Alpha-Tocopherol, D-Alpha-Tocopheryl Succinate)
67 mg
Thiamine (Thiamine Hydrochloride)
125 mg 76
Riboflavin (Riboflavin 5-Phosphate)
50 mg 70
Niacin (Niacinamide, Niacinamide Ascorbate)
190 mg NE
Vitamin B6
105 mg 68
Folate (L-5-Methyltetrahydrofolate, Calcium Salt)
400 mcg DFE
Vitamin B12 (Methylcobalamin)
600 mcg 76
Biotin
3000 mcg 78
Pantothenic Acid (D-Calcium Pantothenate)
600 mg 80
Calcium (Calcium Ascorbate, Calcium D-Glucarate, Calcium D-Pantothenate, Dicalcium Phosphate)
140 mg
Iodine (Potassium Iodide)
150 mcg 84
Magnesium (Magnesium Arginate, Magnesium Ascorbate, Magnesium Citrate, Magnesium Glycinate, Magnesium Oxide, Magnesium Taurinate)
420 mg 53
Zinc (L-OptiZinc Zinc Mono-L-Methionine Sulfate, Zinc Citrate)
35 mg 71
Selenium (Se-Methyl L-Selenocysteine, SelenoExcell High Selenium Yeast, Sodium Selenite)
200 mcg 64
Copper (Copper Bisglycinate Chelate)
1 mg 72
Manganese (Manganese Citrate, Manganese Gluconate)
1 mg
Chromium (Crominex 3+ Chromium)
500 mcg 54
Molybdenum (Molybdenum Amino Acid Chelate)
125 mcg 58
Potassium (Potassium Citrate)
35 mg
Broccoli concentrate blend (Broccoli powder, extract, Calcium D-Glucarate)
725 mg
N-Acetyl-L-Cysteine
600 mg
decaffeinated Green Tea extract (Epigallocatechin Gallate)
325 mg 61
Acerola extract
300 mg 35
Inositol
250 mg
Bitter Orange Citrus Bioflavonoids (Hesperidin)
200 mg
Fruit/Berry Proprietary Blend
200 mg
Taurine
200 mg 50
Wild Blueberry Anthocyanin extract
150 mg
Sensoril Ashwagandha extract (Glycoside Conjugates, Oligosaccharides)
125 mg 50
Silymarin (Milk Thistle extract)
100 mg
Trimethylglycine (Betaine Anhydrous)
100 mg
CherryPure Sour Cherry (Tart Cherry) Proanthocyanidin powder
85 mg
Pomella Pomegranate extract (Punicalagins)
85 mg
natural Mixed Tocopherols (Alpha-Tocopherol, Beta-Tocopherol, Delta Tocopherol, Gamma-Tocopherol)
60 mg
MirtoSelect Bilberry extract
30 mg
BioVin Grape Proanthocyanidin extract
25 mg
Leucoselect Grape seed Proanthocyanidin extract
25 mg
Bio-Quercetin Phytosome
15 mg
Bromelain (Pineapple)
15 mg
Lutein (Marigold extract)
15 mg
Olive extract (Hydroxytyrosol, Oleuropein, Polyphenols, Tyrosol)
12.5 mg
Sesame seed Lignan extract
10 mg
Luteolin (Japanese Sophora)
8 mg
Apigenin
5 mg 39
Boron (Boron Amino Acid Chelate)
3 mg 59
Lycopene (LycoBeads natural Tomato extract)
3 mg 70
Delphinidins (Delphinol Maqui berry (Aristotelia chilensis) extract)
2 mg
Cyanidin-3-Glucoside (Black Currant extract)
1.25 mg
Adults 18–50
Report overview
A+ Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyF Value
B+ Active Ingredient Quality & BioavailabilityB Dose, Safety & Label TransparencyF Value
+13
Each serving provides a substantial 35 mg of zinc alongside 1 mg of copper, giving a zinc-heavy balance in the saved evaluation. The citrate and L-monomethionine sulfate sources are identified, but their individual proportions remain unknown.
How this ingredient is rated

Active Ingredient Quality & Bioavailability84

Zinc citrate and zinc L-monomethionine sulfate are favorable form choices, but their actual proportions are unknown. The blend cannot be treated as an equal split.
Zinc Form Bioavailability
Both zinc sources are identified, but their actual shares are undisclosed, limiting how precisely the combination can be compared.

Dose, Safety & Label Transparency79

The zinc and copper amounts are both known, but their balance is zinc-heavy in the supplied assessment.
Elemental Dose Transparency
The label clearly identifies 35 mg elemental zinc per serving and names its sources.
Zinc Dosage Safety & Effectiveness
35 mg per serving provides a substantial zinc amount with a favorable amount assessment.
Zinc-to-Copper Mineral Balance
35 mg zinc and 1 mg copper give a 35:1 ratio, a zinc-heavy balance in the supplied assessment.

Value30

The whole-product serving costs about $1.80. The price is high in the supplied comparison.
Price Per Serving Efficiency
About $1.80 per whole-product serving. The price covers the complete formula, not zinc alone.
F Active Ingredient Quality & BioavailabilityA- Dose, Safety & Label TransparencyD- Value
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. [Comparative study of the urinary excretion of boron, calcium, magnesium and phosphorus in postmenopausal women with and without osteoporosis].
    José Ramón V; Mora Mora M; Marino Alarcón O; Hernández G; Josefina Linares L; Urdaneta Romero H; Arévalo González E · Investigacion clinica · 2013
    Case-control study45 participantsBone Health forBoron
  2. Effect of dietary boron on mineral, estrogen, and testosterone metabolism in postmenopausal women.
    Nielsen FH; Hunt CD; Mullen LM; Hunt JR · FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 1987
    Single-arm trial12 participantsBone Health forBoron
  3. The relationship between boron and magnesium status and bone mineral density in the human: a review.
    Volpe SL; Taper LJ; Meacham S · Magnesium research · 1994
    Narrative reviewBone Health forBoron
  4. Effects of boron supplementation on bone mineral density and dietary, blood, and urinary calcium, phosphorus, magnesium, and boron in female athletes.
    Meacham SL; Taper LJ; Volpe SL · Environmental health perspectives · 1995
    Randomized trial28 participantsBone Health forBoron
  5. Metabolic responses of postmenopausal women to supplemental dietary boron and aluminum during usual and low magnesium intake: boron, calcium, and magnesium absorption and retention and blood mineral concentrations
    C D Hunt, J L Herbel, F H Nielsen · The American Journal of Clinical Nutrition · 1997
    Non-randomized trial11 participantsBone Health forBoron
  6. What is the impact of daily oral supplementation of vitamin D3 (cholecalciferol) plus calcium on the incidence of hip fracture in older people? A systematic review and meta-analysis.
    Manoj P; Derwin R; George S · International journal of older people nursing · 2023
    Meta-analysis12,620 participants7 studies pooledBone Health forCalcium
  7. Calcium supplementation prevents seasonal bone loss and changes in biochemical markers of bone turnover in elderly New England women: a randomized placebo-controlled trial.
    Storm D; Eslin R; Porter ES; Musgrave K; Vereault D; Patton C; Kessenich C; Mohan S; Chen T; Holick MF; Rosen CJ · The Journal of clinical endocrinology and metabolism · 1998
    Randomized trial60 participantsBone Health forCalcium
  8. The effects of calcium supplementation (milk powder or tablets) and exercise on bone density in postmenopausal women.
    Prince R; Devine A; Dick I; Criddle A; Kerr D; Kent N; Price R; Randell A · Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 1995
    Randomized trial168 participantsBone Health forCalcium
  9. The efficacy of calcium supplementation alone in elderly Thai women over a 2-year period: a randomized controlled trial.
    Rajatanavin R; Chailurkit L; Saetung S; Thakkinstian A; Nimitphong H · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2014
    Randomized trial404 participantsBone Health forCalcium
  10. Calcium-enriched foods and bone mass growth in prepubertal girls: a randomized, double-blind, placebo-controlled trial.
    Bonjour JP; Carrie AL; Ferrari S; Clavien H; Slosman D; Theintz G; Rizzoli R · The Journal of clinical investigation · 1997
    Randomized trial149 participantsBone Health forCalcium
  11. The Association between Dietary and Circulating Copper Levels and Osteoporosis: a Scoping Review.
    Ju Y; Xiong W; Pang Y; Chen Z; Hou J; Zheng S; Li Z; Liu T; Xia H; Xia M; Zhong Y; Li J; Jiang X · Biological trace element research · 2026
    Scoping review18 studies pooledBone Health forCopper
  12. Association between dietary copper, iron, zinc, selenium intake and osteopenia or osteoporosis in elderly hypertensive patients: a retrospective cohort study.
    Chen M; Jia L; Gao R · Frontiers in nutrition · 2024
    Cohort study5,286 participantsBone Health forCopper
  13. Associations of dietary copper intake with total bone mineral density and lumbar spine bone mineral density in American adults.
    Hu M; Wang Z; Li C; Zheng Y; Hu J · Medicine · 2025
    Cross-sectional studyBone Health forCopper
  14. The association between dietary mineral intake and bone mineral density: a cross-sectional study.
    Wei M; Wei J; Huang S · Journal of health, population, and nutrition · 2025
    Cross-sectional study11,520 participantsBone Health forCopper
  15. Association between dietary copper intake and bone mineral density in children and adolescents aged 8-19 years: A cross-sectional study.
    Cui A; Yan J; Li H; Fan Z; Wei X; Wang H; Zhuang Y · PloS one · 2024
    Cross-sectional study6,965 participantsBone Health forCopper
  16. Association between RBC folate and lumbar bone mineral density in postmenopausal women, a cross-sectional study from NHANES 2009-2018.
    Wei H; Jin Z; Zhou L; Tang G; Chai S; Che X; Tan Y; Zeng W · Frontiers in endocrinology · 2025
    Cross-sectional study1,315 participantsBone Health forFolate
  17. Genetic variants modify the associations of concentrations of methylmalonic acid, vitamin B-12, vitamin B-6, and folate with bone mineral density.
    Liu CT; Karasik D; Xu H; Zhou Y; Broe K; Cupples LA; Cpgm de Groot L; Ham A; Hannan MT; Hsu YH; Jacques P; McLean RR; Paul L; Selhub J; Trajanoska K; van der Velde N; van Schoor N; Kiel DP · The American journal of clinical nutrition · 2021
    Cohort study4,310 participantsBone Health forFolate
  18. Adequate Intake and Supplementation of B Vitamins, in Particular Folic Acid, can Play a Protective Role in Bone Health.
    Rondanelli M; Tartara A; Fossari F; Vecchio V; Faliva MA; Naso M; Perna S; Nichetti M; Peroni G · Current aging science · 2022
    Narrative review35,298 participants29 studies pooledBone Health forFolate Bone Health forVitamin B6
  19. Relation of homocysteine, folate, and vitamin B12 to bone mineral density of postmenopausal women.
    Cagnacci A; Baldassari F; Rivolta G; Arangino S; Volpe A · Bone · 2004
    Cross-sectional study161 participantsBone Health forFolate
  20. Dietary intake of folate, but not vitamin B2 or B12, is associated with increased bone mineral density 5 years after the menopause: results from a 10-year follow-up study in early postmenopausal women.
    Rejnmark L; Vestergaard P; Hermann AP; Brot C; Eiken P; Mosekilde L · Calcified tissue international · 2008
    Cohort study1,869 participantsBone Health forFolate