B-Complex 100

B-Complex 100

The Vitamin Shoppe4.7 (195 ratings)
Format:Capsule Quantity: 100 Capsule(s) · 100 servings
Goals
$23.99 $0.23 per serving

Product analysis

68 out of 100

B-Complex 100 may help with tiredness when low B-vitamin intake is responsible.

AI assessment of the formula, label and price. How scoring works

Nutrient Quality58

Ingredient-form quality varies across the formula, with clearly identified B6 and active biotin among its strengths. Folate and inositol are unspecified, while some other forms offer more modest quality.

Ingredient Transparency93

All ingredient amounts and most forms are clearly stated for comparison. Folate and inositol are the exceptions because their forms are unspecified.

Value For Money53

Value is mixed, with favorable costs for riboflavin and B6 but weaker value for B5 and choline. Several other ingredients lack reliable cost comparisons.

Customer Satisfaction73

Customer feedback is strongly positive. The modest number of reviews gives a useful but limited picture of satisfaction.

Product Focus69

The clearest use is filling B-vitamin gaps that contribute to fatigue or impaired normal nutrient functions. The high vitamin B6 amount calls for care with routine use.

Format
Capsule
Container
100 Capsule(s)
Per serving
$0.23
Customer rating
4.7 · 195 ratings
Report analysis

Goals

Impact
High effect
A- Ingredient FitF PathwaysB EvidenceA+ Formulation Logic
Vitamin B5 · 100 mgRiboflavin · 100 mgThiamin · 100 mgVitamin B12 · 100 mcg

Folate, Niacin, Vitamin B6, Vitamin B12, Vitamin B5 and Vitamin B2 (Riboflavin) can help reduce tiredness when inadequate intake causes deficiency-related fatigue. B12 and folate support normal red-blood-cell formation; deficiency-related anaemia can cause weakness. These functions do not establish an energy boost when intake is already adequate. The B12 amount falls below the saved comparison threshold, despite its nutritional role.

How this product is rated for Energy

Ingredient fit87

Vitamin B2 (Riboflavin) anchors the recognized ingredient fit, with declared amounts fully meeting the saved comparisons.
Goal fit
Recognized energy-related ingredients share the formula with ingredients serving other goals, reducing its focus.
Dose adequacy
The declared amounts fully meet the saved comparisons; these are not proven fatigue-treatment doses.

Pathways0

The saved result identifies no coverage of its specific energy pathways. Nutritional fatigue support remains distinct from alertness or exercise capacity.
Depth
No specific energy pathway receives coverage, even though the saved result recognizes nutritional contributions.
Breadth
No energy pathway reaches the saved breadth threshold.

Evidence78

Vitamin B2 (Riboflavin) leads the recognized evidence, but the supplied context limits how broadly its findings apply.
Evidence strength
Vitamin B2 (Riboflavin) supplies the strongest recognized evidence here, subject to the population and application limits described for it.
Studied preparation
The saved findings accept the qualifying preparations; this does not establish form superiority.

Formulation logic100

No required partner is missing, and no configured sedative conflict is present. The recognized amounts reach the saved minimum comparison.
Partner coverage
The recognized ingredients have no missing required partner for their assigned contributions.
Conflicts
No configured sedative conflict applies: valerian, kava, qualifying tryptophan and melatonin are absent.
Effective doses
All recognized ingredients reach the saved minimum amount comparison; that threshold is not proof of a clinical energy effect.
Study evidence
Thiamin Disputed 12 studies
Impact
Highest effect
A- Ingredient FitB+ PathwaysB+ EvidenceA Formulation Logic
Folate · 667 mcg DFEVitamin B12 · 100 mcg

The B vitamins provide nutrients used in everyday metabolism, while folate contributes to the nutrients involved in blood formation. These contributions are most useful when dietary intake falls short; larger amounts do not establish better energy or disease prevention, and the different forms receive no demonstrated superiority. The 100 mg vitamin B6 serving triggers the supplied high-dose formulation concern.

How this product is rated for Everyday Health

Ingredient fit88

The declared nutrients provide the product’s connection to general health. Amount coverage is partial in the saved finding.
Goal fit
The nutritional ingredients provide the main connection to this goal, although the product is linked to other health aims.
Dose adequacy
The counted amounts provide partial coverage of the saved reference range; this does not measure clinical benefit or nutrient absorption.

Pathways80

The strongest connection is energy metabolism cofactors. The broader findings also reflect the functional areas identified by the individual rules.
Depth
The strongest recorded connection is energy metabolism cofactors, with full coverage in the saved findings.
Breadth
The recorded findings cover energy metabolism cofactors, one-carbon metabolism and blood formation. Other general-health functions receive less or no coverage.

Evidence82

Vitamin B9 (Folate) leads the saved evidence finding. Nutritional availability when intake is low is distinct from proven improvement above adequacy.
Evidence strength
Vitamin B9 (Folate) leads the saved evidence finding; the supplied context supports conditional nutrient availability, rather than extra benefit above adequacy.
Studied preparation
The counted preparations receive full recognition in the saved finding, without establishing superiority for their chemical forms or delivery methods.

Formulation logic93

The high vitamin B6 serving raises the recorded formulation concern, despite the counted ingredients meeting the amount threshold.
Partner coverage
No missing partner reduced the counted ingredients’ contributions; this finding does not establish synergy.
Conflicts
The 100 mg vitamin B6 serving triggers the supplied high-dose formulation concern.
Effective doses
All counted ingredients meet the saved amount threshold; smaller excluded amounts are distinct from proven ineffectiveness.
Study evidence
Folate Supportive 80 studies
Impact
High effect
B+ Ingredient FitF PathwaysA+ EvidenceA+ Formulation Logic
Biotin · 300 mcgNiacin · 100 mg NEVitamin B12 · 100 mcgRiboflavin · 100 mgThiamin · 100 mgVitamin B5 · 100 mgVitamin B6 · 100 mg

B vitamins help the body use carbohydrates, fats and protein through their coenzyme roles. Supplying more than adequate intake does not establish a rise in resting or daily energy expenditure. The formula's recognized amounts reflect a comparison framework rather than proof that high B-vitamin amounts accelerate metabolism. Methylcobalamin does not establish a superior metabolism-boost effect.

How this product is rated for Metabolism Support

Ingredient fit81

B vitamins supply the credited contributions, though linked to several goals.
Goal fit
B vitamins supply the credited contributions, though linked to several goals.
Dose adequacy
Most amounts reach their saved benchmarks; B12 and biotin receive partial amount recognition.

Pathways0

The saved findings show no coverage of the configured metabolic-rate pathways, despite recognizing the nutrients' amounts.
Depth
None of the configured metabolic-rate pathways receives coverage from the credited nutrients.
Breadth
No area reaches the saved threshold for substantial coverage.

Evidence100

Thiamin leads the saved evidence finding, and the credited preparations are recognized. Normal nutrient or cellular roles still differ from measured whole-body energy expenditure.
Evidence strength
Thiamin leads the saved evidence finding; the clinical scope and outcome limitations described above still apply.
Studied preparation
The saved findings recognize the credited preparations; this does not establish a sustained metabolism or fat-loss effect.

Formulation logic100

No unmet partner requirement or configured conflict was found. All credited ingredients clear the amount threshold used for inclusion.
Partner coverage
Each credited ingredient works independently or has its required partner.
Conflicts
No configured conflict was matched among the evaluated combinations.
Effective doses
All credited ingredients clear the inclusion threshold; this is not proof of an effective energy-expenditure dose.
Study evidence
Biotin Supportive 5 studies
Niacin Supportive 17 studies
Thiamin Supportive 11 studies
Vitamin B6 Supportive 16 studies
Hair Health
Impact
High effect
B Ingredient FitF PathwaysB EvidenceA+ Formulation Logic
Biotin · 300 mcg

Biotin can contribute when deficiency causes hair problems; this does not establish extra growth with adequate intake. Folate supports normal cell division, while vitamin B12 serves as a nutrient cofactor. These roles do not establish an independent hair-growth effect, and niacin’s proposed circulation role also lacks an established oral hair-outcome dose.

How this product is rated for Hair Health

Ingredient fit78

The formula includes relevant nutrients alongside other actives, making its focus broader than hair health. Most assessed amounts make substantial contributions against the comparison anchors, while some contribute less.
Goal fit
The formula includes relevant nutrients alongside other actives, making its focus broader than hair health.
Dose adequacy
Most assessed amounts make substantial contributions against the comparison anchors, while some contribute less.

Pathways0

No contribution was recorded for the specific hair mechanisms evaluated here.
Depth
No contribution was recorded for the specific hair mechanisms evaluated here.
Breadth
None of the evaluated hair mechanisms reached the coverage threshold.

Evidence78

Vitamin B12 leads the eligible evidence contribution. Normal nutrient roles and preparation matches do not by themselves prove routine hair regrowth.
Evidence strength
Vitamin B12 provides the strongest eligible evidence contribution, with the limitations of its specific hair-health role still applying.
Studied preparation
The eligible preparations were treated as matching those in the supplied comparisons; this does not establish benefit for every hair concern.

Formulation logic100

The relevant ingredients have no unmet partner requirement or configured conflict. Their retained amounts meet the minimum comparison threshold.
Partner coverage
The relevant ingredients have no unmet partner requirement in the supplied findings.
Conflicts
No configured ingredient conflict was found; this is not a comprehensive safety assessment.
Effective doses
All ingredients retained for this check meet its minimum amount threshold; that threshold is not a proven effective hair-growth dose.
Study evidence
Biotin Supportive 4 studies
Folate Mixed 15 studies
Niacin Disputed 2 studies

Ingredients

IngredientAmount per servingScore
Thiamine (Thiamine Mononitrate)
100 mg 76
Riboflavin
100 mg 72
Niacin (Niacinamide)
100 mg NE
Vitamin B6 (Pyridoxine Hydrochloride)
100 mg 72
Folate
667 mcg DFE
Vitamin B12 (Methylcobalamin)
100 mcg 59
Biotin (D-Biotin)
300 mcg 66
Pantothenic Acid (D-Calcium Pantothenate)
100 mg 70
Choline (Choline Bitartrate)
19 mg 50
Inositol
100 mg
Gluten Free Adults 18–50 Dairy Free
Report overview
B- Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyD- Value
The serving lists 100 mg of thiamin as thiamine mononitrate, a larger amount in this comparison. The whole-product price works out to about $0.24 per 100 mg of thiamin, which is relatively high for this comparison.
How this ingredient is rated

Active Ingredient Quality & Bioavailability70

Thiamine mononitrate is a standard water-soluble form of thiamin. The additive check did not flag a sweetener or color on its list; no minimal-additive claim was recorded.
Thiamin Chemical Form
Thiamine mononitrate is a standard water-soluble form of thiamin.
Excipient Purity
The additive check did not flag a sweetener or color on its list; no minimal-additive claim was recorded.

Dose, Safety & Label Transparency100

The serving lists 100 mg of thiamin, a larger amount in this comparison. The amount is clearly disclosed.
Thiamin Dosage Potency
The serving lists 100 mg of thiamin, a larger amount in this comparison.
Label Transparency & Proprietary Blends
The label provides the thiamin amount: 100 mg per serving.

Value40

The whole-product price works out to about $0.24 per 100 mg of thiamin, which is relatively high for this comparison.
Price per Declared Dose
The whole-product price works out to about $0.24 per 100 mg of thiamin, which is relatively high for this comparison.
Riboflavin · 100 mg OverallScore72
F Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyA+ Value
Each serving provides 100 mg of riboflavin, and the cost per serving is low. It uses Riboflavin. No artificial colors, flavors or synthetic sweeteners are listed.
How this ingredient is rated

Active Ingredient Quality & Bioavailability30

It uses Riboflavin.
Riboflavin Form Quality
It uses Riboflavin.

Dose, Safety & Label Transparency100

Each serving provides 100 mg of riboflavin. No artificial colors, flavors or synthetic sweeteners are listed.
Dosage for Energy & Metabolism
Each serving provides 100 mg of riboflavin.
R5P Elemental Yield Transparency
The stated amount is standard riboflavin, so phosphate yield is not an issue.
Additive Purity
No artificial colors, flavors or synthetic sweeteners are listed.

Value100

The cost per serving is low.
Price per Serving Value
The cost per serving is low.
A+ Ingredient Form & Label QualityF Dose, Safety & Label TransparencyA+ Value
Each serving contains 100 mg of vitamin B6, a high amount that raises safety concerns. The recorded sources are pyridoxine hydrochloride.
How this ingredient is rated

Ingredient Form & Label Quality100

The recorded B6 source is pyridoxine hydrochloride.
Vitamin B6 Form Identification
The recorded B6 form is pyridoxine hydrochloride.
Clean Label and Excipient Purity
The recorded other-ingredients information does not flag the colors, titanium dioxide, hydrogenated oils or talc checked here.

Dose, Safety & Label Transparency30

The 100 mg of vitamin B6 per serving is a high amount that raises safety concerns. The chemical source is identified.
Vitamin B6 Dose & Safety Policy
The 100 mg of vitamin B6 per serving is a high amount that raises safety concerns.
Label Transparency
The chemical source is identified as pyridoxine hydrochloride.

Value100

A whole-product serving costs about $0.24 for 100 mg of B6, relatively low per mg. The price covers the whole product.
Vitamin B6 Price Efficiency
A whole-product serving costs about $0.24 for 100 mg of B6, relatively low per mg. The price covers the whole product.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Physicochemical properties of and volatile compounds in riboflavin fortified cloudy apple juice; study of its effect on job fatigue among Egyptian construction workers.
    Fouad S; Ibrahim GE; Hussein AMS; Ibrahim FA; El Gendy A · Heliyon · 2021
    Non-randomized trialEnergy forRiboflavin
  2. Vitamin B status in patients with chronic fatigue syndrome.
    Heap LC; Peters TJ; Wessely S · Journal of the Royal Society of Medicine · 1999
    Case-control study30 participantsEnergy forRiboflavin
  3. B-vitamins, related vitamers, and metabolites in patients with quiescent inflammatory bowel disease and chronic fatigue treated with high dose oral thiamine.
    Bager P; Hvas CL; Hansen MM; Ueland P; Dahlerup JF · Molecular medicine (Cambridge, Mass.) · 2023
    Observational studyEnergy forRiboflavin
  4. Metabolic features of chronic fatigue syndrome.
    Naviaux RK; Naviaux JC; Li K; Bright AT; Alaynick WA; Wang L; Baxter A; Nathan N; Anderson W; Gordon E · Proceedings of the National Academy of Sciences of the United States of America · 2024
    Case-control study84 participantsEnergy forRiboflavin
  5. Effectiveness of Riboflavin in Inherited Metabolic Diseases: A Systematic Review
    Bregje Jaeger, Nina N Stolwijk, Femke Aaldering, Charlotte A Ruys, Marije Smits, Nicole I Wolf, Carla E M Hollak, Annet M Bosch · Journal of Inherited Metabolic Disease · 2026
    Systematic review381 studies pooledEnergy Metabolism Support forRiboflavin
  6. Influence of thiamin supplementation on the health and general well-being of an elderly Irish population with marginal thiamin deficiency.
    Smidt LJ; Cremin FM; Grivetti LE; Clifford AJ · Journal of gerontology · 1991
    Randomized trial80 participantsEnergy forThiamin
  7. Randomised clinical trial: high-dose oral thiamine versus placebo for chronic fatigue in patients with quiescent inflammatory bowel disease.
    Bager P; Hvas CL; Rud CL; Dahlerup JF · Alimentary pharmacology & therapeutics · 2021
    Randomized trial40 participantsEnergy forThiamin
  8. Dietary reference values for thiamin.
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA); Turck D; Bresson JL; Burlingame B; Dean T; Fairweather-Tait S; Heinonen M; Hirsch-Ernst KI; Mangelsdorf I; McArdle HJ; Naska A; Nowicka G; Pentieva K; Sanz Y; Siani A; Sjödin A; Stern M; Tomé D; Van Loveren H; Vinceti M; Willatts P; Lamberg-Allardt C; Przyrembel H; Tetens I; Gudelj Rakic J; Ioannidou S; de Sesmaisons-Lecarré A; Forss AC; Neuhäuser-Berthold M · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusEnergy forThiamin
  9. Effects of thiamine supplementation on exercise-induced fatigue.
    Suzuki M; Itokawa Y · Metabolic brain disease · 1996
    Randomized trial16 participantsEnergy forThiamin
  10. Long-term maintenance treatment with 300 mg thiamine for fatigue in patients with inflammatory bowel disease: results from an open-label extension of the TARIF study.
    Bager P; Hvas CL; Rud CL; Dahlerup JF · Scandinavian journal of gastroenterology · 2022
    Randomized trialEnergy forThiamin
  11. A new perspective on vitamin B12 deficiency in rheumatology: a case-based review.
    Dułak NA; Rytlewska M; Jaskólska M; Chmielewski M · Rheumatology international · 2024
    Case series3 participantsEnergy forVitamin B12
  12. Effects of Vitamin B12 Supplementation on Cognitive Function, Depressive Symptoms, and Fatigue: A Systematic Review, Meta-Analysis, and Meta-Regression.
    Markun S; Gravestock I; Jäger L; Rosemann T; Pichierri G; Burgstaller JM · Nutrients · 2021
    Meta-analysis6,276 participants16 studies pooledEnergy forVitamin B12
  13. Patients' experiences with methylcobalamin injections in amyotrophic lateral sclerosis.
    Zubair AS; Saab L; Scharer K; Khokhar B · Brain circulation · 2024
    Qualitative study5 participantsEnergy forVitamin B12
  14. Cobalamin deficiency: clinical picture and radiological findings.
    Briani C; Dalla Torre C; Citton V; Manara R; Pompanin S; Binotto G; Adami F · Nutrients · 2014
    Narrative reviewEnergy forVitamin B12
  15. Vitamin B12 Deficiency: Common Questions and Answers.
    Patel H; McGuirk R · American family physician · 2025
    Narrative reviewEnergy forVitamin B12
  16. Intakes of Folate, Vitamin B6, and Vitamin B12 in Relation to All-Cause and Cause-Specific Mortality: A National Population-Based Cohort.
    Bo Y; Xu H; Zhang H; Zhang J; Wan Z; Zhao X; Yu Z · Nutrients · 2022
    Cohort study55,569 participantsEveryday Health forFolate
  17. The responsiveness of plasma homocysteine to small increases in dietary folic acid: a primary care study.
    Schorah CJ; Devitt H; Lucock M; Dowell AC · European journal of clinical nutrition · 1998
    Randomized trial119 participantsEveryday Health forFolate
  18. Associations of Serum Folate and Homocysteine Concentrations with All-Cause, Cardiovascular Disease, and Cancer Mortality in Men and Women in Korea: the Cardiovascular Disease Association Study.
    Song S; Song BM; Park HY · The Journal of nutrition · 2023
    Cohort study21,260 participantsEveryday Health forFolate
  19. The concept of folic acid supplementation and its role in prevention of neural tube defect among pregnant women: PRISMA.
    Seyoum Tola F · Medicine · 2024
    Systematic reviewEveryday Health forFolate
  20. Systematic review of adverse health outcomes associated with high serum or red blood cell folate concentrations.
    Colapinto CK; O'Connor DL; Sampson M; Williams B; Tremblay MS · Journal of public health (Oxford, England) · 2017
    Systematic review71,847 participants46 studies pooledEveryday Health forFolate