Hema-Plex Chewables Delicious Mixed Berry Flavor

Hema-Plex Chewables Delicious Mixed Berry Flavor

NaturesPlus4.8 (11,450 ratings)
Format:Gummy Quantity: 60 Tablet(s) · 20 servings
Goals
$11.43 $0.57 per serving

Product analysis

52 out of 100

Hema-Plex Chewables Delicious Mixed Berry Flavor combines iron with B vitamins to support energy and blood formation when intake is low.

AI assessment of the formula, label and price. How scoring works

Nutrient Quality40

Most nutrient forms are named, with a reasonably favorable manganese chelate. The botanical blend composition and a special quality advantage for many other ingredients remain uncertain.

Ingredient Transparency77

Amounts and most ingredient forms are stated. The proprietary plant-compound blend is not broken down, making its contribution harder to compare.

Value For Money39

Value is mixed, with moderate value for copper and manganese and a relatively costly iron serving. Uncertain value for the other nutrients limits a confident judgment of the full combination.

Customer Satisfaction93

Customer feedback is very positive across many thousands of ratings. The large review base gives a broad picture of satisfaction without proving that additional iron is suitable.

Product Focus22

Iron and B vitamins provide a clear connection to blood formation and tiredness linked to low intake. The substantial iron serving makes an identified iron need especially relevant.

Format
Gummy
Container
60 Tablet(s)
Per serving
$0.57
Customer rating
4.8 · 11,450 ratings
Report analysis

Goals

Impact
Highest effect
B+ Ingredient FitB+ PathwaysB+ EvidenceA Formulation Logic
Folate · 667 mcg DFEVitamin B12 · 1000 mcgSelenium · 30 mcgZinc · 9 mgVitamin C · 180 mg
Study evidence
Folate Supportive 80 studies
Selenium Supportive 70 studies
Vitamin C Supportive 56 studies
Zinc Supportive 60 studies
Impact
High effect
B- Ingredient FitF PathwaysA+ EvidenceA+ Formulation Logic
Vitamin B5 · 7.5 mgRiboflavin · 2.55 mgThiamin · 2.25 mgVitamin B12 · 1000 mcgIron · 85 mg
Study evidence
Iron Supportive 74 studies
Thiamin Disputed 12 studies
Hair Health
Impact
High effect
B- Ingredient FitF PathwaysA+ EvidenceA+ Formulation Logic
Zinc · 9 mgIron · 85 mgVitamin C · 180 mg
Study evidence
Copper Adverse 4 studies
Folate Mixed 15 studies
Iron Disputed 25 studies
Niacin Disputed 2 studies
Selenium Disputed 7 studies
Vitamin E No effect 3 studies
Zinc Supportive 22 studies
Impact
Moderate effect
C Ingredient FitF PathwaysA EvidenceA+ Formulation Logic
Iron · 85 mgVitamin B12 · 1000 mcgVitamin B12 · 1000 mcgVitamin B6 · 3 mgZinc · 9 mg
Study evidence
Iron Supportive 69 studies
Zinc Supportive 11 studies

Ingredients

IngredientAmount per servingScore
Vitamin C (Ascorbic Acid)
180 mg
Vitamin E (D-Alpha-Tocopheryl Acetate)
15 mg
Thiamine (Thiamine Hydrochloride)
2.25 mg
Riboflavin
2.55 mg
Niacin (Niacinamide)
15 mg NE
Vitamin B6 (Pyridoxine Hydrochloride)
3 mg
Folate (Calcium L-5-Methyltetrahydrofolate)
667 mcg DFE
Vitamin B12 (Methylcobalamin)
1000 mcg 84
Pantothenic Acid (Calcium Pantothenate)
7.5 mg
Calcium (Calcium Amino Acid Chelate/Complex)
75 mg
Iron (Ferrous Fumarate)
85 mg 39
Zinc (Zinc Monomethionine)
9 mg
Selenium (Selenium Amino Acid Chelate)
30 mcg
Copper (Copper Amino Acid Chelate)
2 mg 67
Manganese (Manganese Amino Acid Chelate/Complex)
4 mg 78
Proanthoplex (Proprietary Proanthocyanidin/Bioflavonoid Complex)
45 mg
Beet
45 mg
L-Cysteine
30 mg
Gluten Free Adults 18–50 Vegan Dairy Free Vegetarian
Report overview
B- Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyD+ Value
A serving provides 4 mg of manganese at a moderate cost per serving. The source is manganese amino acid chelate. The specific amino acid is not named.
How this ingredient is rated

Active Ingredient Quality & Bioavailability70

The source is manganese amino acid chelate. The specific amino acid is not named.
Manganese Chemical Form
The source is manganese amino acid chelate. The specific amino acid is not named.

Dose, Safety & Label Transparency100

A serving provides 4 mg of manganese.
Manganese Dosage Efficacy & Safety
A serving provides 4 mg of manganese.
Elemental Weight Disclosure
The manganese amount is stated as 4 mg per serving.

Value50

The cost per serving is moderate.
Price per Serving vs. Median
The cost per serving is moderate.
C- Active Ingredient Quality & BioavailabilityA- Dose, Safety & Label TransparencyD+ Value
2 mg of copper per serving comes at a moderately high cost per serving. The source is copper amino acid chelate. The serving also has 9 mg of zinc, a 4.5:1 zinc-to-copper ratio.
How this ingredient is rated

Active Ingredient Quality & Bioavailability58

The source is copper amino acid chelate. The specific amino acid carrier is unclear.
Copper Form Bioavailability
The source is copper amino acid chelate.
Elemental Copper Labeling Clarity
The label states the copper amount and its source.

Dose, Safety & Label Transparency85

The serving provides 2 mg of copper. The serving also has 9 mg of zinc, a 4.5:1 zinc-to-copper ratio.
Copper Dosage Safety & Efficacy
The serving provides 2 mg of copper.
Zinc-to-Copper Balance
The serving also has 9 mg of zinc, a 4.5:1 zinc-to-copper ratio.

Value50

The cost per serving is moderately high.
Price Per Serving Efficiency
The cost per serving is moderately high.
A+ Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyF Value
It provides 1000 mcg of B12 per serving, a high amount, at a high cost per amount of B12. It uses Methylcobalamin, a bioactive form.
How this ingredient is rated

Active Ingredient Quality & Bioavailability100

It uses Methylcobalamin, a bioactive form.
Bioactive B12 Form Selection
It uses Methylcobalamin, a bioactive form.

Dose, Safety & Label Transparency100

Each serving provides 1000 mcg of B12. The amount and form are stated.
Therapeutic Dosage Level
Each serving provides 1000 mcg of B12, a high amount.
Label and Form Transparency
The label states both the B12 amount and its Methylcobalamin form.

Value20

The cost per amount of B12 is high.
Price per 1,000 mcg B12
The cost per amount of B12 is high.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Large-dose intravenous ferric carboxymaltose injection for iron deficiency anemia in heavy uterine bleeding: a randomized, controlled trial.
    Van Wyck DB; Mangione A; Morrison J; Hadley PE; Jehle JA; Goodnough LT · Transfusion · 2010
    Randomized trial477 participantsEnergy forIron
  2. The Effect of Parenteral or Oral Iron Supplementation on Fatigue, Sleep, Quality of Life and Restless Legs Syndrome in Iron-Deficient Blood Donors: A Secondary Analysis of the IronWoMan RCT.
    Macher S; Herster C; Holter M; Moritz M; Matzhold EM; Stojakovic T; Pieber TR; Schlenke P; Drexler C; Amrein K · Nutrients · 2021
    Randomized trial176 participantsEnergy forIron
  3. Ferric carboxymaltose vs. oral iron in the treatment of pregnant women with iron deficiency anemia: an international, open-label, randomized controlled trial (FER-ASAP).
    Breymann C; Milman N; Mezzacasa A; Bernard R; Dudenhausen J; FER-ASAP investigators · Journal of perinatal medicine · 2018
    Randomized trial252 participantsEnergy forIron
  4. Effect of iron therapy on fatigue symptoms in non-anaemic iron deficient women of reproductive age- A Randomized Controlled Trial.
    Sultana N; Bajwa FA; Sikandar MZ; Haider MM; Majeed T · JPMA. The Journal of the Pakistan Medical Association · 2026
    Randomized trial164 participantsEnergy forIron
  5. Intravenous iron isomaltoside treatment of women suffering from severe fatigue after postpartum hemorrhage.
    Holm C; Thomsen LL; Langhoff-Roos J · The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians · 2019
    Randomized trial85 participantsEnergy forIron
  6. Physicochemical properties of and volatile compounds in riboflavin fortified cloudy apple juice; study of its effect on job fatigue among Egyptian construction workers.
    Fouad S; Ibrahim GE; Hussein AMS; Ibrahim FA; El Gendy A · Heliyon · 2021
    Non-randomized trialEnergy forRiboflavin
  7. Vitamin B status in patients with chronic fatigue syndrome.
    Heap LC; Peters TJ; Wessely S · Journal of the Royal Society of Medicine · 1999
    Case-control study30 participantsEnergy forRiboflavin
  8. B-vitamins, related vitamers, and metabolites in patients with quiescent inflammatory bowel disease and chronic fatigue treated with high dose oral thiamine.
    Bager P; Hvas CL; Hansen MM; Ueland P; Dahlerup JF · Molecular medicine (Cambridge, Mass.) · 2023
    Observational studyEnergy forRiboflavin
  9. Metabolic features of chronic fatigue syndrome.
    Naviaux RK; Naviaux JC; Li K; Bright AT; Alaynick WA; Wang L; Baxter A; Nathan N; Anderson W; Gordon E · Proceedings of the National Academy of Sciences of the United States of America · 2024
    Case-control study84 participantsEnergy forRiboflavin
  10. Effectiveness of Riboflavin in Inherited Metabolic Diseases: A Systematic Review
    Bregje Jaeger, Nina N Stolwijk, Femke Aaldering, Charlotte A Ruys, Marije Smits, Nicole I Wolf, Carla E M Hollak, Annet M Bosch · Journal of Inherited Metabolic Disease · 2026
    Systematic review381 studies pooledEnergy forRiboflavin
  11. Influence of thiamin supplementation on the health and general well-being of an elderly Irish population with marginal thiamin deficiency.
    Smidt LJ; Cremin FM; Grivetti LE; Clifford AJ · Journal of gerontology · 1991
    Randomized trial80 participantsEnergy forThiamin
  12. Randomised clinical trial: high-dose oral thiamine versus placebo for chronic fatigue in patients with quiescent inflammatory bowel disease.
    Bager P; Hvas CL; Rud CL; Dahlerup JF · Alimentary pharmacology & therapeutics · 2021
    Randomized trial40 participantsEnergy forThiamin
  13. Dietary reference values for thiamin.
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA); Turck D; Bresson JL; Burlingame B; Dean T; Fairweather-Tait S; Heinonen M; Hirsch-Ernst KI; Mangelsdorf I; McArdle HJ; Naska A; Nowicka G; Pentieva K; Sanz Y; Siani A; Sjödin A; Stern M; Tomé D; Van Loveren H; Vinceti M; Willatts P; Lamberg-Allardt C; Przyrembel H; Tetens I; Gudelj Rakic J; Ioannidou S; de Sesmaisons-Lecarré A; Forss AC; Neuhäuser-Berthold M · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusEnergy forThiamin
  14. Effects of thiamine supplementation on exercise-induced fatigue.
    Suzuki M; Itokawa Y · Metabolic brain disease · 1996
    Randomized trial16 participantsEnergy forThiamin
  15. Long-term maintenance treatment with 300 mg thiamine for fatigue in patients with inflammatory bowel disease: results from an open-label extension of the TARIF study.
    Bager P; Hvas CL; Rud CL; Dahlerup JF · Scandinavian journal of gastroenterology · 2022
    Randomized trialEnergy forThiamin
  16. A new perspective on vitamin B12 deficiency in rheumatology: a case-based review.
    Dułak NA; Rytlewska M; Jaskólska M; Chmielewski M · Rheumatology international · 2024
    Case series3 participantsEnergy forVitamin B12
  17. Effects of Vitamin B12 Supplementation on Cognitive Function, Depressive Symptoms, and Fatigue: A Systematic Review, Meta-Analysis, and Meta-Regression.
    Markun S; Gravestock I; Jäger L; Rosemann T; Pichierri G; Burgstaller JM · Nutrients · 2021
    Meta-analysis6,276 participants16 studies pooledEnergy forVitamin B12
  18. Patients' experiences with methylcobalamin injections in amyotrophic lateral sclerosis.
    Zubair AS; Saab L; Scharer K; Khokhar B · Brain circulation · 2024
    Qualitative study5 participantsEnergy forVitamin B12
  19. Cobalamin deficiency: clinical picture and radiological findings.
    Briani C; Dalla Torre C; Citton V; Manara R; Pompanin S; Binotto G; Adami F · Nutrients · 2014
    Narrative reviewEnergy forVitamin B12
  20. Vitamin B12 Deficiency: Common Questions and Answers.
    Patel H; McGuirk R · American family physician · 2025
    Narrative reviewEnergy forVitamin B12