B-Complex 50

B-Complex 50

The Vitamin Shoppe4.7 (195 ratings)
Format:Capsule Quantity: 100 Capsule(s) · 100 servings
Goals
$17.99 $0.17 per serving

Product analysis

64 out of 100

B-Complex 50 may help with tiredness linked to inadequate B-vitamin intake. Its nutritional roles do not establish faster calorie burning when needs are already met.

AI assessment of the formula, label and price. How scoring works

Nutrient Quality59

B6 and d-biotin have clearly identified sources, and B5 uses calcium D-pantothenate. Folate and some added ingredients remain unspecified, while the B5 source proportions are missing.

Ingredient Transparency72

Ingredient amounts and most sources are stated. Some forms and the applicable B5 source proportions are missing, limiting a full comparison.

Value For Money56

Riboflavin and B6 have favorable cost comparisons, while biotin and PABA offer reasonable value. B5 and choline are less economical, and several other contributions cannot be compared confidently.

Customer Satisfaction73

Customer ratings are strongly positive across a moderate number of entries. They offer some context for satisfaction without establishing an energy or metabolism effect.

Product Focus66

The clearest use is filling B-vitamin gaps relevant to normal energy metabolism. The additional ingredients broaden the formula without establishing extra energy when nutritional needs are already met.

Format
Capsule
Container
100 Capsule(s)
Per serving
$0.17
Customer rating
4.7 · 195 ratings
Report analysis

Goals

Impact
High effect
B+ Ingredient FitF PathwaysB EvidenceA+ Formulation Logic
Vitamin B5 · 50 mgRiboflavin · 50 mgThiamin · 50 mgVitamin B12 · 50 mcg
Study evidence
Thiamin Disputed 12 studies
Impact
High effect
B Ingredient FitF PathwaysA+ EvidenceA+ Formulation Logic
Biotin · 300 mcgNiacin · 50 mg NEVitamin B12 · 50 mcgRiboflavin · 50 mgThiamin · 50 mgVitamin B5 · 50 mgVitamin B6 · 50 mg
Study evidence
Biotin Supportive 5 studies
Niacin Supportive 17 studies
Thiamin Supportive 11 studies
Vitamin B6 Supportive 16 studies

Ingredients

IngredientAmount per servingScore
Thiamine (Thiamine Mononitrate)
50 mg 76
Riboflavin
50 mg 72
Niacin (Niacinamide)
50 mg NE
Vitamin B6 (Pyridoxine Hydrochloride)
50 mg 75
Folate
667 mcg DFE
Vitamin B12 (Methylcobalamin)
50 mcg
Biotin (D-Biotin)
300 mcg 66
Pantothenic Acid (D-Calcium Pantothenate, Vitamin B5)
50 mg 70
Choline (Choline Bitartrate)
50 mg 55
Inositol
50 mg
PABA
50 mg 84
Gluten Free Adults 18–50 Dairy Free Sugar Free
Report overview
PABA · 50 mg OverallScore84
B+ Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyB- Value
The serving contains 50 mg of PABA. The whole-product cost per 100 mg of PABA is moderate; it may overstate the cost attributable to PABA. PABA is named, but no pharmaceutical grade or purity claim is available. The other ingredients do not list artificial colors, titanium dioxide or hydrogenated oils.
How this ingredient is rated

Active Ingredient Quality & Bioavailability80

PABA is named, but no pharmaceutical grade or purity claim is available.
PABA Source & Grade
PABA is named, but no pharmaceutical grade or purity claim is available.

Dose, Safety & Label Transparency95

The serving contains 50 mg of PABA. The other ingredients do not list artificial colors, titanium dioxide or hydrogenated oils.
PABA Dosage Alignment
The serving contains 50 mg of PABA.
Label Disclosure Clarity
The PABA amount is stated as 50 mg per serving.
Additive and Excipient Quality
The other ingredients do not list artificial colors, titanium dioxide or hydrogenated oils.

Value70

The whole-product cost per 100 mg of PABA is moderate; it may overstate the cost attributable to PABA.
Price per 100mg PABA
The whole-product cost per 100 mg of PABA is moderate; it may overstate the cost attributable to PABA.
A+ Ingredient Form & Label QualityF Dose, Safety & Label TransparencyA+ Value
A serving provides 50 mg of vitamin B6 at a low cost for that amount. The amount is above the range favored for this purpose. The named B6 form is Pyridoxine Hydrochloride.
How this ingredient is rated

Ingredient Form & Label Quality100

The named B6 form is Pyridoxine Hydrochloride. The listed ingredients do not indicate the specified artificial colors, titanium dioxide, hydrogenated oils, or talc.
Vitamin B6 Form Identification
The named B6 form is Pyridoxine Hydrochloride.
Clean Label and Excipient Purity
The listed ingredients do not indicate the specified artificial colors, titanium dioxide, hydrogenated oils, or talc.

Dose, Safety & Label Transparency37

A serving provides 50 mg of vitamin B6, an amount above the range favored for this purpose. The B6 source is identified as Pyridoxine Hydrochloride.
Vitamin B6 Dose & Safety Policy
A serving provides 50 mg of vitamin B6, an amount above the range favored for this purpose.
Label Transparency
The B6 source is identified as Pyridoxine Hydrochloride.

Value100

The cost per amount of vitamin B6 is low.
Vitamin B6 Price Efficiency
The cost per amount of vitamin B6 is low.
Riboflavin · 50 mg OverallScore72
F Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyA+ Value
Each serving provides 50 mg of riboflavin, and the cost per serving is low. It uses Riboflavin. No artificial colors, flavors or synthetic sweeteners are listed.
How this ingredient is rated

Active Ingredient Quality & Bioavailability30

It uses Riboflavin.
Riboflavin Form Quality
It uses Riboflavin.

Dose, Safety & Label Transparency100

Each serving provides 50 mg of riboflavin. No artificial colors, flavors or synthetic sweeteners are listed.
Dosage for Energy & Metabolism
Each serving provides 50 mg of riboflavin.
R5P Elemental Yield Transparency
The stated amount is standard riboflavin, so phosphate yield is not an issue.
Additive Purity
No artificial colors, flavors or synthetic sweeteners are listed.

Value100

The cost per serving is low.
Price per Serving Value
The cost per serving is low.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Physicochemical properties of and volatile compounds in riboflavin fortified cloudy apple juice; study of its effect on job fatigue among Egyptian construction workers.
    Fouad S; Ibrahim GE; Hussein AMS; Ibrahim FA; El Gendy A · Heliyon · 2021
    Non-randomized trialEnergy forRiboflavin
  2. Vitamin B status in patients with chronic fatigue syndrome.
    Heap LC; Peters TJ; Wessely S · Journal of the Royal Society of Medicine · 1999
    Case-control study30 participantsEnergy forRiboflavin
  3. B-vitamins, related vitamers, and metabolites in patients with quiescent inflammatory bowel disease and chronic fatigue treated with high dose oral thiamine.
    Bager P; Hvas CL; Hansen MM; Ueland P; Dahlerup JF · Molecular medicine (Cambridge, Mass.) · 2023
    Observational studyEnergy forRiboflavin
  4. Metabolic features of chronic fatigue syndrome.
    Naviaux RK; Naviaux JC; Li K; Bright AT; Alaynick WA; Wang L; Baxter A; Nathan N; Anderson W; Gordon E · Proceedings of the National Academy of Sciences of the United States of America · 2024
    Case-control study84 participantsEnergy forRiboflavin
  5. Effectiveness of Riboflavin in Inherited Metabolic Diseases: A Systematic Review
    Bregje Jaeger, Nina N Stolwijk, Femke Aaldering, Charlotte A Ruys, Marije Smits, Nicole I Wolf, Carla E M Hollak, Annet M Bosch · Journal of Inherited Metabolic Disease · 2026
    Systematic review381 studies pooledEnergy Metabolism Support forRiboflavin
  6. Influence of thiamin supplementation on the health and general well-being of an elderly Irish population with marginal thiamin deficiency.
    Smidt LJ; Cremin FM; Grivetti LE; Clifford AJ · Journal of gerontology · 1991
    Randomized trial80 participantsEnergy forThiamin
  7. Randomised clinical trial: high-dose oral thiamine versus placebo for chronic fatigue in patients with quiescent inflammatory bowel disease.
    Bager P; Hvas CL; Rud CL; Dahlerup JF · Alimentary pharmacology & therapeutics · 2021
    Randomized trial40 participantsEnergy forThiamin
  8. Dietary reference values for thiamin.
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA); Turck D; Bresson JL; Burlingame B; Dean T; Fairweather-Tait S; Heinonen M; Hirsch-Ernst KI; Mangelsdorf I; McArdle HJ; Naska A; Nowicka G; Pentieva K; Sanz Y; Siani A; Sjödin A; Stern M; Tomé D; Van Loveren H; Vinceti M; Willatts P; Lamberg-Allardt C; Przyrembel H; Tetens I; Gudelj Rakic J; Ioannidou S; de Sesmaisons-Lecarré A; Forss AC; Neuhäuser-Berthold M · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusEnergy forThiamin
  9. Effects of thiamine supplementation on exercise-induced fatigue.
    Suzuki M; Itokawa Y · Metabolic brain disease · 1996
    Randomized trial16 participantsEnergy forThiamin
  10. Long-term maintenance treatment with 300 mg thiamine for fatigue in patients with inflammatory bowel disease: results from an open-label extension of the TARIF study.
    Bager P; Hvas CL; Rud CL; Dahlerup JF · Scandinavian journal of gastroenterology · 2022
    Randomized trialEnergy forThiamin
  11. A new perspective on vitamin B12 deficiency in rheumatology: a case-based review.
    Dułak NA; Rytlewska M; Jaskólska M; Chmielewski M · Rheumatology international · 2024
    Case series3 participantsEnergy forVitamin B12
  12. Effects of Vitamin B12 Supplementation on Cognitive Function, Depressive Symptoms, and Fatigue: A Systematic Review, Meta-Analysis, and Meta-Regression.
    Markun S; Gravestock I; Jäger L; Rosemann T; Pichierri G; Burgstaller JM · Nutrients · 2021
    Meta-analysis6,276 participants16 studies pooledEnergy forVitamin B12
  13. Patients' experiences with methylcobalamin injections in amyotrophic lateral sclerosis.
    Zubair AS; Saab L; Scharer K; Khokhar B · Brain circulation · 2024
    Qualitative study5 participantsEnergy forVitamin B12
  14. Cobalamin deficiency: clinical picture and radiological findings.
    Briani C; Dalla Torre C; Citton V; Manara R; Pompanin S; Binotto G; Adami F · Nutrients · 2014
    Narrative reviewEnergy forVitamin B12
  15. Vitamin B12 Deficiency: Common Questions and Answers.
    Patel H; McGuirk R · American family physician · 2025
    Narrative reviewEnergy forVitamin B12
  16. Biotin and contribution to normal energy-yielding metabolism: evaluation of a health claim pursuant to Article 14 of Regulation (EC) No 1924/2006.
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusMetabolism Support forBiotin
  17. Pregnancy and lactation alter biomarkers of biotin metabolism in women consuming a controlled diet.
    Perry CA; West AA; Gayle A; Lucas LK; Yan J; Jiang X; Malysheva O; Caudill MA · The Journal of nutrition · 2015
    Clinical trial75 participantsMetabolism Support forBiotin
  18. Survey of the effect of biotin on glycemic control and plasma lipid concentrations in type 1 diabetic patients in kermanshah in iran (2008-2009)
    Hemmati M, Babaei H, Abdolsalehei M · Oman Medical Journal · 2013
    Randomized trial70 participantsMetabolism Support forBiotin
  19. Chromium picolinate and biotin combination improves glucose metabolism in treated, uncontrolled overweight to obese patients with type 2 diabetes
    César A Albarracin, Bobby C Fuqua, James L Evans, Ira D Goldfine · Diabetes/Metabolism Research and Reviews · 2008
    Randomized trial348 participantsMetabolism Support forBiotin
  20. Biotin supplementation reduces plasma triacylglycerol and VLDL in type 2 diabetic patients and in nondiabetic subjects with hypertriglyceridemia
    Cristina Revilla-Monsalve, Iván Zendejas-Ruiz, Sergio Islas-Andrade, Armida Báez-Saldaña, Miguel Angel Palomino-Garibay, Pedro Martín Hernández-Quiróz, Cristina Fernandez-Mejia · Biomedicine & Pharmacotherapy · 2006
    Randomized trial33 participantsMetabolism Support forBiotin