BioActive Complete B-Complex

BioActive Complete B-Complex

Life Extension4.8 (112,922 ratings)
Format:Capsule Quantity: 60 Capsule(s) · 30 servings
Goals
$9.00 $0.30 per serving

Product analysis

66 out of 100

BioActive Complete B-Complex supplies B vitamins that support normal energy use and blood formation, particularly when intake is low. Missing proportions within several nutrient mixtures make precise comparisons harder.

AI assessment of the formula, label and price. How scoring works

Nutrient Quality56

Several B vitamins use clearly named, favorable forms. Missing mixture proportions and unspecified biotin, inositol and PABA forms limit a complete quality comparison.

Ingredient Transparency72

All listed amounts and most forms are disclosed. Missing proportions within several nutrient mixtures and three missing form descriptions prevent a fully precise comparison.

Value For Money55

Vitamin B6 and B2 offer the clearest value, while thiamin and PABA are less cost-efficient. Several other ingredients have uncertain value, leaving a mixed price case.

Customer Satisfaction95

Customer feedback is very positive. More than a hundred thousand ratings provide an extensive view of satisfaction, without establishing health benefits.

Product Focus65

The clearest role is filling nutrient gaps that affect normal energy use, blood formation and nerve function. The high vitamin B6 amount is linked with sensory nerve problems during long-term use.

Format
Capsule
Container
60 Capsule(s)
Per serving
$0.30
Customer rating
4.8 · 112,922 ratings
Report analysis

Goals

Impact
High effect
B+ Ingredient FitF PathwaysB+ EvidenceA+ Formulation Logic
Vitamin B5 · 500 mgRiboflavin · 75 mgThiamin · 100 mgVitamin B12 · 300 mcg
Study evidence
Thiamin Disputed 12 studies
Impact
Highest effect
A- Ingredient FitB+ PathwaysB+ EvidenceA Formulation Logic
Folate · 680 mcg DFEVitamin B12 · 300 mcg
Study evidence
Folate Supportive 80 studies
Impact
High effect
B+ Ingredient FitF PathwaysA+ EvidenceA+ Formulation Logic
Biotin · 1000 mcgNiacin · 100 mg NEVitamin B12 · 300 mcgRiboflavin · 75 mgThiamin · 100 mgVitamin B5 · 500 mgVitamin B6 · 100 mg
Study evidence
Biotin Supportive 5 studies
Niacin Supportive 17 studies
Thiamin Supportive 11 studies
Vitamin B6 Supportive 16 studies
Impact
High effect
B Ingredient FitF PathwaysB+ EvidenceA+ Formulation Logic
Biotin · 1000 mcg
Study evidence
Biotin Supportive 4 studies
Folate Mixed 15 studies
Niacin Disputed 2 studies

Ingredients

IngredientAmount per servingScore
Thiamine (Thiamine Hydrochloride)
100 mg 76
Riboflavin (Riboflavin 5-Phosphate)
75 mg 84
Niacin (Niacinamide)
100 mg NE
Vitamin B6 (Pyridoxal 5-Phosphate, Pyridoxine Hydrochloride)
100 mg 72
Folate (L-5-Methyltetrahydrofolate, Calcium Salt)
680 mcg DFE
Vitamin B12 (Methylcobalamin)
300 mcg 67
Biotin
1000 mcg 69
Pantothenic Acid (D-Calcium Pantothenate)
500 mg 86
Calcium (Calcium D-Pantothenate, Dicalcium Phosphate)
90 mg
Inositol
100 mg
PABA
50 mg 78
Gluten Free Adults 18–50
Report overview
B- Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyD- Value
Each serving provides 100 mg of thiamin at a high cost per amount of thiamin. It uses thiamine hydrochloride, a standard water-soluble form.
How this ingredient is rated

Active Ingredient Quality & Bioavailability70

Thiamine Hydrochloride is a standard water-soluble form.
Thiamin Chemical Form
Thiamine Hydrochloride is a standard water-soluble form.
Excipient Purity
No listed artificial sweeteners or colors were flagged; that does not establish a filler-free formula.

Dose, Safety & Label Transparency100

The label states 100 mg of thiamin per serving. The amount falls in the higher range used for metabolic and neurological support.
Thiamin Dosage Potency
The 100 mg amount falls in the higher range used for metabolic and neurological support.
Label Transparency & Proprietary Blends
The label states 100 mg of thiamin per serving.

Value40

The cost per amount of thiamin is high.
Price per Declared Dose
The cost per amount of thiamin is high.
PABA · 50 mg OverallScore78
B+ Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyD- Value
A serving provides 50 mg of PABA, with a high cost relative to the amount. The cost uses the full serving price, so it may overstate the cost of PABA alone. The PABA is named, but its grade is unspecified. No artificial colors, titanium dioxide or hydrogenated oils are listed.
How this ingredient is rated

Active Ingredient Quality & Bioavailability80

PABA is named, but a pharmaceutical grade or high-purity designation is not stated.
PABA Source & Grade
The ingredient is identified as PABA without a specific grade.

Dose, Safety & Label Transparency95

The serving states 50 mg of PABA. No artificial colors, titanium dioxide or hydrogenated oils are listed.
PABA Dosage Alignment
The serving provides 50 mg of PABA.
Label Disclosure Clarity
The PABA amount is listed separately.
Additive and Excipient Quality
The listed ingredients show no artificial colors, titanium dioxide or hydrogenated oils.

Value40

The full serving price makes the cost per amount of PABA high; it may overstate the cost of PABA alone.
Price per 100mg PABA
The full serving price makes the cost per 100 mg of PABA high, potentially overstating PABA's own cost.
A Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyD+ Value
Each serving provides 500 mg of B5, at a moderate cost for that amount. It uses Calcium D-Pantothenate, a stable, well-absorbed form of B5.
How this ingredient is rated

Active Ingredient Quality & Bioavailability90

It uses Calcium D-Pantothenate, a stable, well-absorbed form of B5.
Vitamin B5 Chemical Form
It uses Calcium D-Pantothenate, a stable, well-absorbed form of B5.

Dose, Safety & Label Transparency100

It provides 500 mg of B5 per serving. The label names the B5 amount and its source.
Dosage Potency and Efficacy
It provides 500 mg of B5 per serving.
Label Transparency & Source Clarity
The label names the B5 amount and its source.

Value50

The cost is moderate for the amount of B5 provided.
Price per 500mg Vitamin B5
The cost is moderate for the amount of B5 provided.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Physicochemical properties of and volatile compounds in riboflavin fortified cloudy apple juice; study of its effect on job fatigue among Egyptian construction workers.
    Fouad S; Ibrahim GE; Hussein AMS; Ibrahim FA; El Gendy A · Heliyon · 2021
    Non-randomized trialEnergy forRiboflavin
  2. Vitamin B status in patients with chronic fatigue syndrome.
    Heap LC; Peters TJ; Wessely S · Journal of the Royal Society of Medicine · 1999
    Case-control study30 participantsEnergy forRiboflavin
  3. B-vitamins, related vitamers, and metabolites in patients with quiescent inflammatory bowel disease and chronic fatigue treated with high dose oral thiamine.
    Bager P; Hvas CL; Hansen MM; Ueland P; Dahlerup JF · Molecular medicine (Cambridge, Mass.) · 2023
    Observational studyEnergy forRiboflavin
  4. Metabolic features of chronic fatigue syndrome.
    Naviaux RK; Naviaux JC; Li K; Bright AT; Alaynick WA; Wang L; Baxter A; Nathan N; Anderson W; Gordon E · Proceedings of the National Academy of Sciences of the United States of America · 2024
    Case-control study84 participantsEnergy forRiboflavin
  5. Effectiveness of Riboflavin in Inherited Metabolic Diseases: A Systematic Review
    Bregje Jaeger, Nina N Stolwijk, Femke Aaldering, Charlotte A Ruys, Marije Smits, Nicole I Wolf, Carla E M Hollak, Annet M Bosch · Journal of Inherited Metabolic Disease · 2026
    Systematic review381 studies pooledEnergy Metabolism Support forRiboflavin
  6. Influence of thiamin supplementation on the health and general well-being of an elderly Irish population with marginal thiamin deficiency.
    Smidt LJ; Cremin FM; Grivetti LE; Clifford AJ · Journal of gerontology · 1991
    Randomized trial80 participantsEnergy forThiamin
  7. Randomised clinical trial: high-dose oral thiamine versus placebo for chronic fatigue in patients with quiescent inflammatory bowel disease.
    Bager P; Hvas CL; Rud CL; Dahlerup JF · Alimentary pharmacology & therapeutics · 2021
    Randomized trial40 participantsEnergy forThiamin
  8. Dietary reference values for thiamin.
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA); Turck D; Bresson JL; Burlingame B; Dean T; Fairweather-Tait S; Heinonen M; Hirsch-Ernst KI; Mangelsdorf I; McArdle HJ; Naska A; Nowicka G; Pentieva K; Sanz Y; Siani A; Sjödin A; Stern M; Tomé D; Van Loveren H; Vinceti M; Willatts P; Lamberg-Allardt C; Przyrembel H; Tetens I; Gudelj Rakic J; Ioannidou S; de Sesmaisons-Lecarré A; Forss AC; Neuhäuser-Berthold M · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusEnergy forThiamin
  9. Effects of thiamine supplementation on exercise-induced fatigue.
    Suzuki M; Itokawa Y · Metabolic brain disease · 1996
    Randomized trial16 participantsEnergy forThiamin
  10. Long-term maintenance treatment with 300 mg thiamine for fatigue in patients with inflammatory bowel disease: results from an open-label extension of the TARIF study.
    Bager P; Hvas CL; Rud CL; Dahlerup JF · Scandinavian journal of gastroenterology · 2022
    Randomized trialEnergy forThiamin
  11. A new perspective on vitamin B12 deficiency in rheumatology: a case-based review.
    Dułak NA; Rytlewska M; Jaskólska M; Chmielewski M · Rheumatology international · 2024
    Case series3 participantsEnergy forVitamin B12
  12. Effects of Vitamin B12 Supplementation on Cognitive Function, Depressive Symptoms, and Fatigue: A Systematic Review, Meta-Analysis, and Meta-Regression.
    Markun S; Gravestock I; Jäger L; Rosemann T; Pichierri G; Burgstaller JM · Nutrients · 2021
    Meta-analysis6,276 participants16 studies pooledEnergy forVitamin B12
  13. Patients' experiences with methylcobalamin injections in amyotrophic lateral sclerosis.
    Zubair AS; Saab L; Scharer K; Khokhar B · Brain circulation · 2024
    Qualitative study5 participantsEnergy forVitamin B12
  14. Cobalamin deficiency: clinical picture and radiological findings.
    Briani C; Dalla Torre C; Citton V; Manara R; Pompanin S; Binotto G; Adami F · Nutrients · 2014
    Narrative reviewEnergy forVitamin B12
  15. Vitamin B12 Deficiency: Common Questions and Answers.
    Patel H; McGuirk R · American family physician · 2025
    Narrative reviewEnergy forVitamin B12
  16. Intakes of Folate, Vitamin B6, and Vitamin B12 in Relation to All-Cause and Cause-Specific Mortality: A National Population-Based Cohort.
    Bo Y; Xu H; Zhang H; Zhang J; Wan Z; Zhao X; Yu Z · Nutrients · 2022
    Cohort study55,569 participantsEveryday Health forFolate
  17. The responsiveness of plasma homocysteine to small increases in dietary folic acid: a primary care study.
    Schorah CJ; Devitt H; Lucock M; Dowell AC · European journal of clinical nutrition · 1998
    Randomized trial119 participantsEveryday Health forFolate
  18. Associations of Serum Folate and Homocysteine Concentrations with All-Cause, Cardiovascular Disease, and Cancer Mortality in Men and Women in Korea: the Cardiovascular Disease Association Study.
    Song S; Song BM; Park HY · The Journal of nutrition · 2023
    Cohort study21,260 participantsEveryday Health forFolate
  19. The concept of folic acid supplementation and its role in prevention of neural tube defect among pregnant women: PRISMA.
    Seyoum Tola F · Medicine · 2024
    Systematic reviewEveryday Health forFolate
  20. Systematic review of adverse health outcomes associated with high serum or red blood cell folate concentrations.
    Colapinto CK; O'Connor DL; Sampson M; Williams B; Tremblay MS · Journal of public health (Oxford, England) · 2017
    Systematic review71,847 participants46 studies pooledEveryday Health forFolate