Vitamin D + K2
Thorne
Vitamin D + K2
4.9
★ ★ ★ ★ ★
(28053 ratings)
Vitamin K 200 mcg
Score 85.0
A high-quality D + K2 supplement from a professional brand, likely effective for bone and heart health, but its specific K2 form, D dosage, and value are undeterminable from provided data.
Quantity: 1 Fluid Ounce(s)Servings size: 2 Drop(s) (600 servings)
Selected goals:
Other goals:
Bone Health
Heart Health
Cardiovascular Support
General Health
leaderboard Score 85.0
A high-quality D + K2 supplement from a professional brand, likely effective for bone and heart health, but its specific K2 form, D dosage, and value are undeterminable from provided data.
insights Analysis
The foundational strength of Thorne's Vitamin D + K2 lies in its strategic pairing of these two vitamins, which act in concert to regulate calcium. Vitamin D facilitates calcium absorption, while Vitamin K2 directs it appropriately within the body, preventing arterial calcification and promoting bone mineralization. Thorne is known for using bioavailable forms of nutrients and adhering to strict quality control, suggesting the K2 (200mcg) is likely effective (e.g., if it's MK-7, it's a good dose; if MK-4, it's moderate and would benefit from higher doses for therapeutic effects, but still beneficial for maintenance). Online sentiment for Thorne products is generally very positive, reflecting trust in the brand's efficacy. The primary limitation for a comprehensive consumer assessment is the absence of explicit Vitamin D dosage and detailed pricing information per serving, which makes direct value comparisons impossible.
- Formulated by Thorne, a highly reputable professional-grade supplement brand.
- Combines Vitamin D and K2, providing essential synergy for calcium metabolism.
- Likely uses high-quality, bioavailable forms of ingredients.
- 200mcg of K2 is a good dose (especially if MK-7).
- Missing specific Vitamin D dosage information.
- Specific form of Vitamin K2 (MK-4 vs. MK-7) not detailed, which impacts efficacy understanding.
- Crucially, price per serving and total servings are null, preventing value assessment and direct comparison.
$28.80($0.04 per serving)
 iHerb | $ 28.80 | |
 Pure Formulas | $ 32.00 | |
 Vitacost | $ 32.00 |
bolt Effectiveness for goals
Vitamin K is essential for proper blood clotting and plays a significant role in bone metabolism. It helps the body produce proteins necessary for these vital bodily functions.
Vitamin K activates proteins such as osteocalcin, which are crucial for incorporating calcium into the bone matrix. This mechanism supports bone mineralization and helps maintain bone density.
Vitamin K1 (phylloquinone) is primarily effective for blood coagulation and is abundant in green leafy vegetables. Vitamin K2 (menaquinones) is more involved in bone and cardiovascular health, found in fermented foods and animal products, and has different bioavailabilities.
Emerging research suggests that Vitamin K, particularly K2, may help prevent arterial calcification by activating matrix Gla protein. This protein helps inhibit calcium deposition in soft tissues, supporting arterial flexibility.
Vitamin K works synergistically with calcium by helping to direct calcium to the bones and away from soft tissues like arteries. It activates proteins like osteocalcin for bone binding and matrix Gla protein to inhibit soft tissue calcification.
schedule Dosage, timing & forms
Recommended dosages for Vitamin K vary by age and form (K1 vs K2). For adults, the Adequate Intake (AI) for Vitamin K is 120 mcg per day for men and 90 mcg per day for women. Specific supplemental dosages may differ depending on individual needs and health goals.
Yes, dosages can differ between Vitamin K1 and K2 due to their varying potencies and half-lives. While K1 is measured in micrograms (mcg) for general intake, K2 (especially MK-7) may be effective at lower microgram doses due to its longer half-life. It's important to check the specific form and dosage on the supplement label.
Yes, Vitamin K is a fat-soluble vitamin, meaning it is best absorbed when taken with a meal containing some dietary fat. This helps facilitate its absorption into the body.
The two main forms of Vitamin K found in supplements are Vitamin K1 (phylloquinone) and Vitamin K2 (menaquinone). Vitamin K2 further has various subtypes, with MK-4 and MK-7 being the most common in supplements. Each form may have distinct roles and bioavailability.
There is no established Upper Limit (UL) for Vitamin K from food or supplements, as toxicity is rare. However, high doses of synthetic Vitamin K (menadione, K3) can be toxic, though this form is not typically found in supplements. Always adhere to recommended dosages and consult a healthcare provider if you have concerns.
health_and_safety Safety & interactions
Vitamin K plays a crucial role in blood clotting, which is the opposite effect of anticoagulant medications such as warfarin. Consuming inconsistent amounts of Vitamin K can alter warfarin's effectiveness, potentially making the blood thinner less effective or increasing bleeding risk. Individuals taking warfarin should maintain a consistent intake of Vitamin K and consult their healthcare provider.
Individuals taking anticoagulant medications like warfarin should consult their doctor before taking Vitamin K supplements due to potential interactions. People with certain liver conditions or those with a G6PD deficiency should also seek medical advice before supplementation. Always discuss new supplements with a healthcare provider.
Vitamin K supplements are generally considered safe for most healthy individuals when taken at recommended dosages. Side effects are uncommon but can include upset stomach, diarrhea, or allergic reactions in sensitive individuals. High doses of synthetic Vitamin K (menadione, K3) can be toxic, but this form is rarely used in supplements.
Vitamin K is essential during pregnancy and breastfeeding, and adequate intake is important for both mother and child. However, supplementation during these periods should only be undertaken under the guidance of a healthcare professional. High doses are generally not recommended without specific medical advice.
There is currently no established Tolerable Upper Intake Level (UL) for Vitamin K from food or supplements due to its low potential for toxicity. However, excessive intake, especially of synthetic forms, could potentially have adverse effects. It is always best to adhere to recommended dosages on supplement labels or as advised by a healthcare professional.
Ingredients
| Ingredient | Amount per serving |
|---|---|
Vitamin D | 25 mcg |
Vitamin K | 200 mcg |
Categories
Vitamin K 90.0
Represents a strong Vitamin K supplement due to its effective K2 dose and critical pairing with Vitamin D, a combination highly recommended by nutritionists for maximum benefit.
Goals
Bone Health 90.0
The synergistic combination of Vitamin D and K2 is foundational for optimal calcium utilization, promoting strong bones and preventing density loss for skeletal integrity.
Heart Health 90.0
K2 plays a vital role in preventing arterial calcification, and its pairing with Vitamin D makes it highly effective in supporting overall heart health and arterial flexibility.
By ensuring calcium is directed away from blood vessel walls, the D+K2 combination provides excellent support for arterial flexibility and comprehensive cardiovascular wellness.
Recommended Alternatives
100 Value 
Mega D-3 5000 IU & MK-7 180 mcg
NOW
4.8
★★★★★
(25386 ratings)
Provides a clearly specified, highly effective D3+MK-7 combination at an exceptionally low price ($0.21/serving), offering superior value and proven efficacy compared to the original with unknown pricing.
98 Value 
ADK Vitamins
Codeage
4.8
★★★★★
(1294 ratings)
Delivers an incredibly high dose of MK-7 (1800mcg) with D and A for just $0.19/serving, offering vastly superior potency and comprehensive benefits for its cost, making it an excellent value.
95 Value 
Super K
Life Extension
4.7
★★★★★
(11302 ratings)
Offers a robust blend of Vitamin K forms (2600mcg total K) at a competitive price ($0.23/serving), providing broad-spectrum K coverage and excellent value compared to the original's ambiguous value proposition.
100 Performance
Mega D-3 5000 IU & MK-7 180 mcg
NOW
4.8
★★★★★
(25386 ratings)
Offers an explicitly stated high dose of MK-7 (180mcg) synergistically combined with 5000 IU of D3, providing clearer and stronger dosing for optimal bone and cardiovascular health than the original's ambiguous details.
98 Performance
ADK Vitamins
Codeage
4.8
★★★★★
(1294 ratings)
Features an exceptionally high dose of MK-7 (1800mcg) along with Vitamins A and D, making it a very potent ADK complex that offers comprehensive benefits for those seeking high-impact supplementation.
93 Performance 
Vitamins D and K with Sea-lodine
Life Extension
4.8
★★★★★
(20811 ratings)
Combines Vitamin D and K (2100mcg K, likely a beneficial blend) with Sea-Iodine, offering additional synergistic benefits beyond D+K alone, potentially providing a more comprehensive supplement for overall wellness.
60 Budget 
Multi For Him
Nature Made
4.7
★★★★★
(1806 ratings)
A multivitamin at $0.11/serving, providing Vitamin K1 (Phytonadione, 80mcg) at a very low cost, representing a significantly cheaper option for general vitamin intake, though not K2-focused.
60 Budget 
Centrum Silver Women 50+
GSK
4.8
★★★★★
(5910 ratings)
A very inexpensive multivitamin ($0.10/serving) including 50mcg of general Vitamin K, offering a budget-friendly way to supplement Vitamin K, albeit K1-focused and lower dose.
60 Budget 
Centrum Silver Women 50+
Centrum
4.8
★★★★★
(7706 ratings)
Another highly affordable multivitamin ($0.09/serving) with 50mcg of Vitamin K, providing a cost-effective alternative for general vitamin support compared to more specialized options.
100 Value
Mega D-3 5000 IU & MK-7 180 mcg
NOW
4.8
★★★★★
(25386 ratings)
Provides a clearly specified, highly effective D3+MK-7 combination at an exceptionally low price ($0.21/serving), offering superior value and proven efficacy compared to the original with unknown pricing.
98 Value
ADK Vitamins
Codeage
4.8
★★★★★
(1294 ratings)
Delivers an incredibly high dose of MK-7 (1800mcg) with D and A for just $0.19/serving, offering vastly superior potency and comprehensive benefits for its cost, making it an excellent value.
95 Value
Super K
Life Extension
4.7
★★★★★
(11302 ratings)
Offers a robust blend of Vitamin K forms (2600mcg total K) at a competitive price ($0.23/serving), providing broad-spectrum K coverage and excellent value compared to the original's ambiguous value proposition.
100 Performance
Mega D-3 5000 IU & MK-7 180 mcg
NOW
4.8
★★★★★
(25386 ratings)
Offers an explicitly stated high dose of MK-7 (180mcg) synergistically combined with 5000 IU of D3, providing clearer and stronger dosing for optimal bone and cardiovascular health than the original's ambiguous details.
98 Performance
ADK Vitamins
Codeage
4.8
★★★★★
(1294 ratings)
Features an exceptionally high dose of MK-7 (1800mcg) along with Vitamins A and D, making it a very potent ADK complex that offers comprehensive benefits for those seeking high-impact supplementation.
93 Performance
Vitamins D and K with Sea-lodine
Life Extension
4.8
★★★★★
(20811 ratings)
Combines Vitamin D and K (2100mcg K, likely a beneficial blend) with Sea-Iodine, offering additional synergistic benefits beyond D+K alone, potentially providing a more comprehensive supplement for overall wellness.