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MK-7 Vitamin K-2 100 mcg

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(31808 ratings)
Vitamin K 100 mcg
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Score87
A strong-value, well-dosed MK-7 capsule with clear labeling, tempered by generic sourcing and dry delivery.
How scoring works
Quantity:60 Capsule(s) • (60 servings)
Goals:
Heart Health
Bone Health
General Health
Cardiovascular Support
Anti-Aging

Score 87

A strong-value, well-dosed MK-7 capsule with clear labeling, tempered by generic sourcing and dry delivery.
How scoring works
$7.00($0.11 per serving)
Vitacost
$ 14.53
Daily Vita
$ 12.70
iHerb
$ 13.46
Pure Formulas
$ 13.08
Walmart
$ 14.78
Amazon
$ 16.85
Daily Vita
$ 7.00
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Analysis

MK-7 is clearly identified at a practical daily amount for vitamin K-dependent calcium handling. Its long-lasting profile suits simple once-daily supplementation.

The single-ingredient capsule offers good value and is easy to combine with separately chosen vitamin D or minerals. No branded source, all-trans claim, or lipid carrier is provided.

The product fits adults wanting straightforward MK-7 without added nutrients. It supports one important bone and arterial pathway rather than broad cardiovascular or skeletal coverage.

Who is it for
  • Adults seeking routine MK-7
  • Value-focused K2 users
  • People building a customized nutrient routine
Best for
  • Calcium-handling proteins
  • Bone-support cofactors
  • Focused arterial-health nutrition

Pros

  • Preferred MK-7 subtype
  • Practical daily amount
  • Low serving cost

Cons

  • No branded or all-trans source claim
  • Dry capsule lacks a lipid carrier
  • No vitamin D companion

Warnings

  • MK-7 can oppose warfarin and related vitamin K antagonist medicines
  • Keep vitamin K intake consistent if anticoagulation therapy permits use
  • Take with a fat-containing meal unless directed otherwise

Nutrient quality

94 Highest impact

Menaquinone-7 is a well-regarded, long-acting vitamin K2 form, and the vitamin K2 amount is meaningful for routine standalone support. The amount is not unnecessarily aggressive for a focused vitamin K2 supplement, while the single-active formula is not padded with low-value ingredients.

Ingredient transparency

84 Highest impact

Specific amounts are listed for every supplied active ingredient. No proprietary blend hides active doses, while capsule, softgel, or tablet excipients are not included in the supplied details.

Customer satisfaction

73 High impact

The supplied aggregate satisfaction metric is very strong, and the large amount of aggregate feedback makes the metric highly stable. No review excerpts were provided, so recurring complaints and purpose-specific experiences cannot be checked.

Value for money

97 Highest impact

A focused formula and well-regarded vitamin K2 form support good value. Each serving provides a meaningful active amount with little burden, while the formula avoids unnecessary active extras.

Report analysis

Goals

Heart Health
Impact
Highest effect
A- Goal FitA Strength of SupportC+ CoverageA+ Formula Quality
Vitamin K · 100 mcg

Vitamin K2 as MK-7 supports calcium placement and may contribute to arterial health. The 100 mcg amount is well aligned with commonly used MK-7 supplementation.

The capsule gives clear subtype disclosure but no lipid carrier or branded source. Vitamin K2 can interfere with warfarin and related vitamin K antagonists, so users of those medicines need managed, consistent vitamin K intake.

Study evidence
Vitamin K Mixed 62 studies
Bone Health
Impact
Highest effect
A- Goal FitA- Strength of SupportC+ CoverageA+ Formula Quality
Vitamin K · 100 mcg

MK-7 directly supports activation of bone-matrix proteins, and the 100 mcg amount is within the preferred range. The subtype and amount are clearly stated, making the intended contribution easy to assess.

The generic source has no branded or all-trans purity claim, and the dry capsule lacks a stated lipid carrier. MK-7 can interfere with warfarin and related vitamin K antagonists, so users of those medicines need consistent intake and clinician-guided management.

Study evidence
Vitamin K Supportive 78 studies
General Health
Impact
Highest effect
A Goal FitA- Strength of SupportC- CoverageA Formula Quality
Vitamin K · 100 mcg

MK-7 supports calcium regulation and long-term bone and vascular foundations at a well-aligned amount. Its role is focused rather than broadly nutritional.

The subtype and dose are clear, though the dry capsule lacks a lipid carrier. MK-7 can interfere with warfarin and other vitamin K antagonist medicines, so users of those drugs need managed, consistent intake.

Study evidence
Vitamin K Supportive 34 studies
Cardiovascular Support
Impact
Highest effect
B Goal FitA+ Strength of SupportD+ CoverageA+ Formula Quality
Vitamin K · 100 mcg

MK-7 vitamin K2 supports calcium regulation that may help maintain arterial flexibility. The formula is focused on one preventive pathway rather than broad cardiovascular support.

The 100 mcg amount and long-acting MK-7 form are clearly disclosed. Vitamin K2 can oppose warfarin and other vitamin K antagonist anticoagulants, so the intake must remain clinician-guided and consistent.

Study evidence
Vitamin K Supportive 40 studies
Anti-Aging
Impact
High effect
B- Goal FitA- Strength of SupportD CoverageA Formula Quality
Vitamin K · 100 mcg

MK-7 provides targeted support for calcium handling in blood vessels and bones. The disclosed amount is well aligned, although the dry capsule has no stated lipid carrier.

Its focused design offers useful depth but covers only one major aging-related theme. MK-7 can interfere with warfarin and related vitamin K antagonists, making consistent clinician-managed vitamin K intake important for users of those medicines.

Study evidence
Vitamin K Supportive 27 studies

Ingredients

IngredientAmount per serving
Vitamin K-2 (Menaquinone-7)
100 mcg
Gluten Free Adults 18–50 Vegan Kosher Dairy Free Vegetarian
Report overview
C+ Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyA+ Value

The capsule supplies a well-aligned MK-7 dose with clear subtype disclosure. Its low serving cost supports excellent dose efficiency, though no branded source or absorption guidance is provided. MK-7 can interfere with warfarin and related vitamin K antagonists, so users of those medicines need managed, consistent vitamin K intake.

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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Three-year low-dose menaquinone-7 supplementation helps decrease bone loss in healthy postmenopausal women.
    Knapen MH; Drummen NE; Smit E; Vermeer C; Theuwissen E · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2014
    Randomized trial244 participantsBone Health forVitamin K
  2. Does vitamin K2 play a role in the prevention and treatment of osteoporosis for postmenopausal women: a meta-analysis of randomized controlled trials.
    Huang ZB; Wan SL; Lu YJ; Ning L; Liu C; Fan SW · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2015
    Meta-analysis6,759 participants19 studies pooledBone Health forVitamin K
  3. Investigating the interrelationship of vitamin K and vitamin D status on bone density: results from the VITamin D and OmegA-3 TriaL.
    Chou SH; Booth SL; Cook NR; Kim E; Kotler G; Fu X; Buring JE; Manson JE; LeBoff MS · JBMR plus · 2026
    Randomized trial771 participantsBone Health forVitamin K
  4. Comparison of concurrent treatment with vitamin K2 and risedronate compared with treatment with risedronate alone in patients with osteoporosis: Japanese Osteoporosis Intervention Trial-03.
    Tanaka S; Miyazaki T; Uemura Y; Miyakawa N; Gorai I; Nakamura T; Fukunaga M; Ohashi Y; Ohta H; Mori S; Hagino H; Hosoi T; Sugimoto T; Itoi E; Orimo H; Shiraki M · Journal of bone and mineral metabolism · 2018
    Randomized trial1,874 participantsBone Health forVitamin K
  5. Efficacy and safety of vitamin K2 for postmenopausal women with osteoporosis at a long-term follow-up: meta-analysis and systematic review.
    Zhou M; Han S; Zhang W; Wu D · Journal of bone and mineral metabolism · 2022
    Meta-analysis6,853 participants9 studies pooledBone Health forVitamin K
  6. Menaquinone-7 supplementation improves arterial stiffness in healthy postmenopausal women. A double-blind randomised clinical trial.
    Knapen MH; Braam LA; Drummen NE; Bekers O; Hoeks AP; Vermeer C · Thrombosis and haemostasis · 2016
    Randomized trial244 participantsCardiovascular Support Heart Health forVitamin K
  7. Effects of One-Year Menaquinone-7 Supplementation on Vascular Stiffness and Blood Pressure in Post-Menopausal Women.
    de Vries F; Bittner R; Maresz K; Machuron F; Gåserød O; Jeanne JF; Schurgers LJ · Nutrients · 2025
    Randomized trial165 participantsCardiovascular Support forVitamin K
  8. Vitamin K Intake and Atherosclerotic Cardiovascular Disease in the Danish Diet Cancer and Health Study.
    Bellinge JW; Dalgaard F; Murray K; Connolly E; Blekkenhorst LC; Bondonno CP; Lewis JR; Sim M; Croft KD; Gislason G; Torp-Pedersen C; Tjønneland A; Overvad K; Hodgson JM; Schultz C; Bondonno NP · Journal of the American Heart Association · 2021
    Cohort study53,372 participantsCardiovascular Support Heart Health forVitamin K
  9. Interventions to Attenuate Cardiovascular Calcification Progression: A Systematic Review of Randomized Clinical Trials.
    Murali S; Smith ER; Tiong MK; Tan SJ; Toussaint ND · Journal of the American Heart Association · 2024
    Systematic review9,901 participants49 studies pooledCardiovascular Support forVitamin K
  10. Intake of dietary phylloquinone and menaquinones and risk of stroke.
    Vissers LE; Dalmeijer GW; Boer JM; Monique Verschuren WM; van der Schouw YT; Beulens JW · Journal of the American Heart Association · 2014
    Cohort study35,476 participantsCardiovascular Support forVitamin K
  11. Circulating uncarboxylated matrix Gla protein, a marker of vitamin K status, as a risk factor of cardiovascular disease.
    van den Heuvel EG; van Schoor NM; Lips P; Magdeleyns EJ; Deeg DJ; Vermeer C; den Heijer M · Maturitas · 2014
    Cohort study577 participantsCardiovascular Support forVitamin K
  12. Vitamin K status, cardiovascular disease, and all-cause mortality: a participant-level meta-analysis of 3 US cohorts.
    Shea MK; Barger K; Booth SL; Matuszek G; Cushman M; Benjamin EJ; Kritchevsky SB; Weiner DE · The American journal of clinical nutrition · 2020
    Meta-analysis3,891 participants3 studies pooledAnti-Aging General Health forVitamin K
  13. Topical Menaquinone‑7 (Vitamin K2, MK-7) as a Mitochondrial Bioenergetic Activator for Skin Anti-Aging: Mechanistic Evidence in Skin Cells and a Randomized Split-Face/Neck Study.
    Huang H; Wei R; Xu C; Liu C; Zhao S; Li Y; Wang M · ACS omega · 2026
    Randomized trial30 participantsAnti-Aging forVitamin K
  14. Vitamin K status and cognitive function in healthy older adults.
    Presse N; Belleville S; Gaudreau P; Greenwood CE; Kergoat MJ; Morais JA; Payette H; Shatenstein B; Ferland G · Neurobiology of aging · 2014
    Cross-sectional study320 participantsAnti-Aging forVitamin K
  15. High dephospho-uncarboxylated matrix Gla protein concentrations, a plasma biomarker of vitamin K, in relation to frailty: the Longitudinal Aging Study Amsterdam.
    Machado-Fragua MD; Hoogendijk EO; Struijk EA; Rodriguez-Artalejo F; Lopez-Garcia E; Beulens JW; van Ballegooijen AJ · European journal of nutrition · 2021
    Cohort study644 participantsAnti-Aging forVitamin K
  16. Vitamin K Concentration and Cognitive Status in Elderly Patients on Anticoagulant Therapy: A Pilot Study.
    Alisi L; Cafolla C; Gentili A; Tartaglione S; Curini R; Cafolla A · Journal of aging research · 2022
    Cross-sectional study85 participantsAnti-Aging forVitamin K
  17. Vitamin K and the prevention of fractures: systematic review and meta-analysis of randomized controlled trials.
    Cockayne S; Adamson J; Lanham-New S; Shearer MJ; Gilbody S; Torgerson DJ · Archives of internal medicine · 2006
    Meta-analysis13 studies pooledBone Health forVitamin K
  18. Effect of combined administration of vitamin D3 and vitamin K2 on bone mineral density of the lumbar spine in postmenopausal women with osteoporosis.
    Iwamoto J; Takeda T; Ichimura S · Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association · 2001
    Randomized trial92 participantsBone Health forVitamin K
  19. Low-dose vitamin K2 (MK-4) supplementation for 12 months improves bone metabolism and prevents forearm bone loss in postmenopausal Japanese women.
    Koitaya N; Sekiguchi M; Tousen Y; Nishide Y; Morita A; Yamauchi J; Gando Y; Miyachi M; Aoki M; Komatsu M; Watanabe F; Morishita K; Ishimi Y · Journal of bone and mineral metabolism · 2015
    Randomized trial48 participantsBone Health forVitamin K
  20. Dietary Vitamin K1 Intake and Incident Aortic Valve Stenosis.
    Schultz CJ; Dalgaard F; Bellinge JW; Murray K; Sim M; Connolly E; Blekkenhorst LC; Bondonno CP; Lewis JR; Gislason GH; Tjønneland A; Overvad K; Hodgson JM; Bondonno NP · Arteriosclerosis, thrombosis, and vascular biology · 2024
    Cohort study55,545 participantsCardiovascular Support Heart Health forVitamin K
  21. Association between vitamin K1 intake and mortality in the Danish Diet, Cancer, and Health cohort.
    Palmer CR; Bellinge JW; Dalgaard F; Sim M; Murray K; Connolly E; Blekkenhorst LC; Bondonno CP; Croft KD; Gislason G; Tjønneland A; Overvad K; Schultz C; Lewis JR; Hodgson JM; Bondonno NP · European journal of epidemiology · 2021
    Cohort study56,048 participantsCardiovascular Support Heart Health forVitamin K
  22. Dietary vitamin K intake associates with reduced all-cause mortality in non-alcoholic fatty liver disease patients.
    Huang Y; Zhu X; Han L; Hu H · Scientific reports · 2025
    Cohort study7,857 participantsGeneral Health forVitamin K
  23. The Effect of Topical Vitamin K1 on the Treatment of Cetuximab-Induced Skin Rashes in Metastatic Colorectal Cancer Patients.
    Roayaei M; Rezaei M; Najafizade N · Advanced biomedical research · 2024
    Randomized trial49 participantsGeneral Health forVitamin K
  24. Effect of vitamin K on improving post‑kidney transplant outcomes: a meta‑analysis.
    Sun Z; Zhu K; Liang G; Yan F; Chao S; Jia L; Niu Y · Experimental and therapeutic medicine · 2023
    Meta-analysis7 studies pooledGeneral Health forVitamin K
  25. Vitamin K1 intake is associated with lower risk for all-cause and cardiovascular disease mortality in community-dwelling older Australian women.
    Dupuy M; Radavelli-Bagatini S; Zhong L; Dalla Via J; Zhu K; Blekkenhorst LC; Bondonno NP; Linneberg A; Bellinge JW; Schultz C; Courtney W; Prince RL; Hodgson JM; Lewis JR; Sim M · Nutrition, metabolism, and cardiovascular diseases : NMCD · 2024
    Cohort study1,436 participantsGeneral Health forVitamin K
  26. The effect of vitamin K1 on arterial calcification activity in subjects with diabetes mellitus: a post hoc analysis of a double-blind, randomized, placebo-controlled trial.
    Bellinge JW; Francis RJ; Lee SC; Bondonno NP; Sim M; Lewis JR; Watts GF; Schultz CJ · The American journal of clinical nutrition · 2022
    Randomized trial149 participantsHeart Health forVitamin K