Product Image

Clearface

Codeage
4.5
★ ★ ★ ★ ★
(527 ratings)
Copper 2 mg
Niacin 25 mg
Lysine 500 mg
Zinc 30 mg
Selenium 200 mcg
Vitamin B5 20 mg
Iodine 113 mcg
Product Image
Score59
A broad mix of skin lipids, omega-3 fats, lysine, antioxidant vitamins, and balanced zinc and copper gives the formula meaningful skin support. Hidden blends and incomplete omega-3 and mineral-form details reduce transparency and value.
How scoring works
Quantity:90 Capsule(s) • (30 servings)
Goals:
Skin Health
Hair Health
Immunity
General Health
Vision Support
Nail Health

Score 59

A broad mix of skin lipids, omega-3 fats, lysine, antioxidant vitamins, and balanced zinc and copper gives the formula meaningful skin support. Hidden blends and incomplete omega-3 and mineral-form details reduce transparency and value.
How scoring works
$29.99($0.99 per serving)
Pure Formulas
$ 29.99
Pure Formulas
$ 29.99
iHerb
$ 29.99
Amazon
$ 29.99
Vitacost
$ 29.99
BodyBuilding.com
$ 29.99
Walmart
$ 29.99
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Analysis

The formula is most convincing for skin support because it combines phytoceramides with EPA and DHA, lysine, zinc, copper, and vitamins A, C, D, and E. These actives address barrier lipids, structural support, repair, and oxidative stress from several angles.

The label supplies substantial omega-3 fats and clearly states the amounts of the main vitamins and minerals. Zinc is paired with copper in a sensible balance, but the omega-3 source and molecular form are missing, and the mineral chelates are not chemically specific.

Hair and immune support are credible secondary uses because several of the same nutrients contribute to follicle structure and normal immune function. Bone, metabolism, and testosterone support are much less complete, while the hidden probiotic and skin-cleanse blends make the full formula harder to judge.

Who is it for
  • Adults seeking broad nutritional support for skin barrier and repair
  • People who want omega-3 fats combined with skin-focused vitamins and minerals
  • Users who are not already taking high-dose zinc or selenium
Best for
  • Skin barrier and hydration support
  • Skin antioxidant and repair support
  • Secondary hair and immune nutrition

Pros

  • Phytoceramides directly support the skin-barrier focus
  • EPA and DHA provide a substantial combined omega-3 amount
  • Zinc is paired with copper in a sensible balance
  • Vitamins A, C, D, and E add broad skin-relevant coverage
  • Lysine adds a useful structural amino acid

Cons

  • Omega-3 source and molecular form are not disclosed
  • Two blends hide their individual ingredients and amounts
  • Mineral chelates are not chemically specific
  • Lacks biotin, silicon, collagen, and macular carotenoids
  • Weak fit for bone, metabolism, and testosterone goals

Warnings

  • The 30 mg zinc and 200 mcg selenium amounts are substantial, so stacking another high-dose zinc or selenium supplement could push total intake unnecessarily high.
  • The omega-3 source is not disclosed, so people avoiding fish or other marine ingredients cannot confirm suitability from the supplied label.

Nutrient quality

73 High impact

Substantial omega fats, lysine, zinc, phytoceramides, and antioxidant nutrients provide broad skin-focused support. Generic chelates, two opaque blends, and a relatively high zinc amount weaken form and dose confidence.

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Ingredient transparency

49 Lower impact

Most vitamins, minerals, amino acids, omega fats, and phytoceramides have specific amounts. Two blends hide their contents, while inactive ingredients and complete directions are not supplied.

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Customer satisfaction

65 High impact

The supplied aggregate rating is positive but not exceptional. The review count is substantial enough to provide useful rating confidence.

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Value for money

49 Lower impact

Substantial omega fats and several meaningful skin-support nutrients provide some support for the premium positioning. Opaque blends and a high serving cost keep the value from being compelling.

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Report analysis

Goals

Skin Health
Impact
Highest effect
A Goal FitA- Strength of SupportA CoverageA- Formula Quality
Zinc · 30 mgVitamin C · 120 mgCopper · 2 mgSelenium · 200 mcgVitamin E · 15 mgOmega-3 · 450 mgCeramide · 35 mg

The formula is strongly and specifically aligned with skin health. Phytoceramides, substantial omega-3 fats, zinc, copper, vitamins A, C, and E, selenium, and lysine cover barrier, repair, structure, and oxidative defense.

The serving is broad, but the ingredients remain connected to clear skin pathways. It offers one of the most complete skin-focused profiles in the supplied group.

Study evidence
Ceramide Not classified

No linked studies yet.

Copper Supportive 16 studies
Omega-3 Supportive 35 studies
Selenium Supportive 22 studies
Vitamin C Supportive 53 studies
Zinc Supportive 66 studies
Hair Health
Impact
Highest effect
B+ Goal FitB+ Strength of SupportA- CoverageB+ Formula Quality
Vitamin D · 25 mcgZinc · 30 mgLysine · 500 mgVitamin C · 120 mg

Lysine, zinc, D3, vitamin C, selenium, copper, and omega-3 fats provide broad structural and deficiency-related hair support. Lysine reaches the lower edge of a useful range, while zinc is substantial and balanced with copper.

The formula is designed for skin but has a credible overlap with hair nutrition. Generic chelates and incomplete omega-3 source and molecular-form details reduce quality confidence.

Study evidence
Copper Adverse 4 studies
Lysine Supportive 1 study
Omega-3 Adverse 4 studies
Selenium Disputed 7 studies
Vitamin C Mixed 5 studies
Zinc Supportive 22 studies
Immunity
Impact
Highest effect
A- Goal FitB+ Strength of SupportA- CoverageC+ Formula Quality
Vitamin C · 120 mgZinc · 30 mgVitamin A · 700 mcgVitamin D · 25 mcgOmega-3 · 450 mgSelenium · 200 mcg

Vitamin D3, zinc, selenium, vitamin A, vitamin C, lysine, and substantial EPA plus DHA cover several immune pathways. Zinc and selenium reach focused amounts, while omega-3 fats support inflammatory resolution.

The formula is sold for skin support, but its quantified nutrient core remains strongly relevant to immunity. Generic mineral chelates, an undisclosed omega-3 source, and two proprietary blends reduce form and label confidence.

Study evidence
Lysine Supportive 2 studies
Omega-3 Supportive 24 studies
Selenium Mixed 37 studies
Vitamin A Supportive 107 studies
Vitamin C Supportive 53 studies
Vitamin D Supportive 85 studies
Zinc Supportive 73 studies
General Health
Impact
High effect
B+ Goal FitB Strength of SupportB CoverageC+ Formula Quality
Vitamin D · 25 mcgSelenium · 200 mcgZinc · 30 mgVitamin C · 120 mg

A broad nutrient base and a substantial combined EPA and DHA serving make the formula meaningfully relevant to daily wellness. Vitamin D3, zinc, selenium, and copper also support several foundational systems.

Most key amounts are clearly stated and the zinc dose is balanced with copper. Confidence is reduced by vaguely named mineral chelates and two blends whose individual ingredients and amounts are not disclosed.

Study evidence
Selenium Supportive 70 studies
Zinc Supportive 60 studies
Vision Support
Impact
High effect
B- Goal FitB Strength of SupportB+ CoverageB- Formula Quality
Zinc · 30 mgVitamin E · 15 mgVitamin C · 120 mgCopper · 2 mgVitamin A · 700 mcg

DHA, EPA, antioxidant vitamins, zinc, selenium, and copper create substantial support for retinal structure and oxidative defense. The zinc-to-copper balance is sensible for continued use.

Missing lutein and zeaxanthin leave macular light filtration uncovered despite the otherwise broad nutrient pattern. The skin-focused blends also make the formula less precise than a dedicated eye supplement.

Study evidence
Copper Supportive 7 studies
Selenium Supportive 15 studies
Vitamin A Supportive 65 studies
Zinc Supportive 39 studies
Nail Health
Impact
High effect
C Goal FitB- Strength of SupportB CoverageB- Formula Quality

Zinc, selenium, copper, vitamin C, lysine, and phytoceramide provide moderate nutritional and protein-building support for nails. The product lacks biotin, silicon, collagen, or keratin, so direct nail-plate coverage is incomplete.

Lysine is meaningfully dosed and the robust zinc amount is balanced with copper. The acne-focused botanical blend adds substantial content that does not directly strengthen nails.

Study evidence
Selenium Adverse 1 study
Vitamin C Supportive 1 study
Zinc No effect 1 study
Testosterone Support
Impact
Moderate effect
C- Goal FitC+ Strength of SupportD+ CoverageF Formula Quality
Zinc · 30 mgVitamin D · 25 mcg

Zinc at 30 mg and vitamin D3 at 25 mcg offer the strongest foundational hormone support, with selenium adding antioxidant coverage. The formula does not include a meaningful stress modulator, boron, or another specialized free-hormone active.

The zinc and selenium chelates are not chemically specific, which limits confidence despite clearly stated amounts. Skin, detox, probiotic, and ceramide ingredients dominate the formula and make it poorly targeted to testosterone support.

Study evidence
Selenium No effect 16 studies
Vitamin D Supportive 56 studies
Zinc Disputed 7 studies

Ingredients

IngredientAmount per serving
Vitamin A (Beta-Carotene)
700 mcg
Vitamin C (L-Ascorbic Acid)
120 mg
Vitamin D3 (Cholecalciferol)
25 mcg
Vitamin E (Rice Bran)
15 mg
Thiamine (Thiamine Hydrochloride)
5 mg
Riboflavin
5 mg
Niacin (Niacinamide)
25 mg
Pantothenic Acid (D-Calcium Pantothenate)
20 mg
Iodine (Kelp)
113 mcg
Zinc (Zinc Amino Acid Chelate)
30 mg
Selenium (Selenium Amino Acid Chelate)
200 mcg
Copper (Copper Amino Acid Chelate)
2 mg
Manganese (Manganese Citrate)
1.6 mg
Chromium (Chromium Picolinate)
60 mcg
L-Lysine Hydrochloride
500 mg
Omega-3 Fatty Acids (Docosahexaenoic Acid, Eicosapentaenoic Acid)
450 mg
Skin Cleanse and Detox Blend
300 mg
Probiotic Blend
117 mg
Phytoceramide (Rice extract)
35 mg
BioPerine (Black Pepper Fruit Extract)
5 mg
Adults 18–50
Report overview
A+ Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyD+ Value

The clearly named copper amino acid chelate supports good absorption. The copper amount matches the collection target, and the zinc-to-copper ratio is well balanced. Serving cost is relatively high for the copper delivered.

Niacin (Niacinamide) · 25 mg OverallScore79
A Active Ingredient Quality & BioavailabilityA- Dose, Safety & Label TransparencyD- Value

Niacinamide is the right B3 form for a skin-focused formula, and the 25 mg amount is clearly disclosed. Standard capsules offer no special release benefit, but the form has a low flush risk. The complex skin formula carries a substantial premium and offers weak niacin-specific value.

D Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyF Value

The generic amino acid chelate may absorb reasonably, but its undisclosed ligand limits confidence. The standard capsule should dissolve efficiently, though it is not identified as a veggie capsule. The 30 mg amount is a robust daily dose, while the high serving cost substantially weakens value.

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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Associations of selenium status with all-cause and cause-specific mortality: a systematic review and meta-analysis of cohort studies.
    Cui Z; Xie R; Lu X; Schomburg L; Brenner H; Schöttker B · Redox biology · 2025
    Meta-analysis95 participants20 studies pooledGeneral Health forSelenium
  2. Dietary Antioxidants, Circulating Antioxidant Concentrations, Total Antioxidant Capacity, and Risk of All-Cause Mortality: A Systematic Review and Dose-Response Meta-Analysis of Prospective Observational Studies.
    Jayedi A; Rashidy-Pour A; Parohan M; Zargar MS; Shab-Bidar S · Advances in nutrition (Bethesda, Md.) · 2019
    Meta-analysis507,251 participants41 studies pooledGeneral Health forSelenium
  3. The efficacy and safety of selenium supplementation versus placebo in the treatment of Graves' orbitopathy: A systematic review and meta-analysis of randomised controlled trials.
    Sharabati I; Qafesha RM; Hindawi MD; Amro S; Ayesh BM · Clinical endocrinology · 2024
    Meta-analysis4 studies pooledGeneral Health Vision Support forSelenium
  4. Associations of plasma metal concentrations with the risks of all-cause and cardiovascular disease mortality in Chinese adults.
    Shi L; Yuan Y; Xiao Y; Long P; Li W; Yu Y; Liu Y; Liu K; Wang H; Zhou L; Yang H; Li X; He M; Wu T · Environment international · 2021
    Cohort study6,155 participantsGeneral Health forSelenium
  5. Updates on clinical studies of selenium supplementation in radiotherapy.
    Puspitasari IM; Abdulah R; Yamazaki C; Kameo S; Nakano T; Koyama H · Radiation oncology (London, England) · 2015
    Systematic review16 studies pooledGeneral Health forSelenium
  6. Effectiveness of sodium bicarbonate and zinc chloride mouthwashes in the treatment of oral mucositis and quality of life in patients with cancer under chemotherapy.
    Mohammadi F; Oshvandi K; Kamallan SR; Khazaei S; Ranjbar H; Ahmadi-Motamayel F; Gillespie M; Jenabi E; Vafaei SY · Nursing open · 2022
    Randomized trial144 participantsGeneral Health forZinc
  7. Zinc supplementation in young children with acute diarrhea in India.
    Sazawal S; Black RE; Bhan MK; Bhandari N; Sinha A; Jalla S · The New England journal of medicine · 1995
    Randomized trial937 participantsGeneral Health forZinc
  8. Associations of mortality with ocular disorders and an intervention of high-dose antioxidants and zinc in the Age-Related Eye Disease Study: AREDS Report No. 13.
    Clemons TE; Kurinij N; Sperduto RD; AREDS Research Group · Archives of ophthalmology (Chicago, Ill. : 1960) · 2004
    Randomized trial4,753 participantsGeneral Health forZinc
  9. Effects of zinc and probiotic co-supplementation on inflammation, gastrointestinal symptoms, quality of life, and mood in irritable bowel syndrome patients.
    Rezazadegan M; Soheilipour M; Amani R · Scientific reports · 2026
    Randomized trial84 participantsGeneral Health forZinc
  10. Effect of zinc sulfate supplementation on premenstrual syndrome and health-related quality of life: Clinical randomized controlled trial.
    Siahbazi S; Behboudi-Gandevani S; Moghaddam-Banaem L; Montazeri A · The journal of obstetrics and gynaecology research · 2018
    Randomized trial142 participantsGeneral Health forZinc
  11. Menkes disease and response to copper histidine: An Indian case series.
    Yoganathan S; Sudhakar SV; Arunachal G; Thomas M; Subramanian A; George R; Danda S · Annals of Indian Academy of Neurology · 2022
    Case series4 participantsHair Health forCopper
  12. Trace element levels in alopecia areata.
    Bhat YJ; Manzoor S; Khan AR; Qayoom S · Indian journal of dermatology, venereology and leprology · 2009
    Case-control study100 participantsHair Health forCopper
  13. UV damage to hair and the effect of antioxidants and metal chelators.
    Millington KR; Marsh JM · International journal of cosmetic science · 2021
    In vitro / ex vivo studyHair Health forCopper
  14. Preserving fibre health: reducing oxidative stress throughout the life of the hair fibre.
    Marsh JM; Davis MG; Lucas RL; Reilman R; Styczynski PB; Li C; Mamak M; McComb DW; Williams RE; Godfrey S; Navqi KR; Chechik V · International journal of cosmetic science · 2016
    In vitro / ex vivo studyHair Health forCopper
  15. Causes of hair loss and the developments in hair rejuvenation.
    Rushton DH; Norris MJ; Dover R; Busuttil N · International journal of cosmetic science · 2010
    Narrative reviewHair Health forLysine
  16. Bioengineered Plants Can Be a Useful Source of Omega-3 Fatty Acids.
    Amjad Khan W; Chun-Mei H; Khan N; Iqbal A; Lyu SW; Shah F · BioMed research international · 2017
    Narrative reviewHair Health forOmega-3
  17. 36th International Symposium on Intensive Care and Emergency Medicine : Brussels, Belgium. 15-18 March 2016.
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Helme E; Broderick R; Hadfield S; Loveridge R; Ramos J; Forte D; Yang F; Hou P; Dudziak J; Feeney J; Wilkinson K; Bauchmuller K; Shuker K; Faulds M; Raithatha A; Bryden D; England L; Bolton N; Tridente A; Bauchmuller K; Shuker K; Tridente A; Faulds M; Matheson A; Gaynor J; Bryden D; S South Yorkshire Hospitals Research Collaboration; Ramos J; Peroni B; Daglius-Dias R; Miranda L; Cohen C; Carvalho C; Velasco I; Forte D; Kelly JM; Neill A; Rubenfeld G; Masson N; Min A; Boezeman E; Hofhuis J; Hovingh A; De Vries R; Spronk P; Cabral-Campello G; Aragão I; Cardoso T; Van Mol M; Nijkamp M; Kompanje E; Ostrowski P; Omar A; Kiss K; Köves B; Csernus V; Molnár Z; Hoydonckx Y; Vanwing S; Stessel B; Van Assche A; Jamaer L; Dubois J; Medo V; Galvez R; Miranda JP; Stone C; Wigmore T; Arunan Y; Wheeler A; Bauchmuller K; Bryden D; Wong Y; Poi C; Gu C; Molmy P; Van Grunderbeeck N; Nigeon O; Lemyze M; Thevenin D; Mallat J; Ramos J; Correa M; Carvalho RT; Forte D; Fernandez A; McBride C; Koonthalloor E; Walsh C; Webber A; Ashe M; Smith K; Jeanrenaud P; Marudi A; Baroni S; Ragusa F; Bertellini E; Volakli EA; Chochliourou E; Dimitriadou M; Violaki A; Mantzafleri P; Samkinidou E; Vrani O; Arbouti A; Varsami T; Sdougka M; Bollen JA; Van Smaalen TC; De Jongh WC; Ten Hoopen MM; Ysebaert D; Van Heurn LW; Van Mook WN; Sim K; Fuller A; Roze des Ordons A; Couillard P; Doig C; Van Keer RV; Deschepper RD; Francke AF; Huyghens LH; Bilsen JB; Nyamaizi B; Dalrymple C; Molokhia A; Dobru A; Marrinan E; Ankuli A; Molokhia A; McPeake J; Struthers R; Crawford R; Devine H; Mactavish P; Quasim T; Morelli P; Degiovanangelo M; Lemos F; MArtinez V; Verga F; Cabrera J; Burghi G; Rutten A; Van Ieperen S; De Geer S; Van Vugt M; Der Kinderen E; Giannini A; Miccinesi G; Marchesi T; Prandi E · Critical care (London, England) · 2024
    Meta-analysisHair Health forOmega-3
  18. [Evaluation of the role of dietary intake in the occurrence of alopecia].
    El Fékih N; Kamoun H; Fazaa B; El Ati J; Zouari B; Kamoun MR; Gaigi S · Revue medicale de Liege · 2010
    Case-control study272 participantsHair Health forOmega-3
  19. Effect of a nutritional supplement on hair loss in women
    Caroline Le Floc'h, Ahsène Cheniti, Sophie Connétable, Nathalie Piccardi, Colombina Vincenzi, Antonella Tosti · Journal of cosmetic dermatology · 2015
    Randomized trial120 participantsHair Health forOmega-3
  20. Beyond Efficacy: 0.6% Selenium Disulfide Shampoo Matches 2% Ketoconazole for Seborrheic Dermatitis with Superior Cosmesis.
    Farris PK; Barbosa V; Houshman EB; Kovylkina N · Journal of drugs in dermatology : JDD · 2026
    Randomized trial87 participantsHair Health forSelenium
  21. Selenium Disulfide-based shampoo applied for 4 weeks significantly improves dandruff and seborrheic dermatitis.
    Turcu G; Artenie C; Nowicka D; Arenbergerová M; Lazaridou E; Khobzei K; Ataseven A; Part M; Leclerc-Mercier S · European journal of dermatology : EJD · 2023
    Observational study1,407 participantsHair Health forSelenium
  22. A Comparative Randomized Clinical Study Assessing the Efficacy of a 1% Selenium Disulfide-Based Shampoo versus 2% Ketoconazole Shampoo in Subjects with Moderate to Severe Scalp Seborrheic Dermatitis.
    Barbosa V; Melo DF; Vañó-Galván S; Lutchmanen-Kolanthan V; Sant'Anna B; Leclerc-Mercier S; Reygagne P · Skin appendage disorders · 2025
    Randomized trial64 participantsHair Health forSelenium
  23. Changes of serum trace elements level in patients with alopecia areata: A meta-analysis.
    Jin W; Zheng H; Shan B; Wu Y · The Journal of dermatology · 2018
    Meta-analysis764 participantsHair Health forSelenium
  24. Scientific opinion on the tolerable upper intake level for selenium.
    EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA); Turck D; Bohn T; Castenmiller J; de Henauw S; Hirsch-Ernst KI; Knutsen HK; Maciuk A; Mangelsdorf I; McArdle HJ; Peláez C; Pentieva K; Siani A; Thies F; Tsabouri S; Vinceti M; Aggett P; Crous Bou M; Cubadda F; Ciccolallo L; de Sesmaisons Lecarré A; Fabiani L; Titz A; Naska A · EFSA journal. European Food Safety Authority · 2023
    Systematic reviewHair Health forSelenium
  25. Management of hair loss associated with endocrine therapy in patients with breast cancer: an overview.
    Karatas F; Sahin S; Sever AR; Altundag K · SpringerPlus · 2016
    Narrative reviewHair Health forVitamin C
  26. Elucidating causal relationships of diet-derived circulating antioxidants and the risk of non-scarring alopecia: A Mendelian randomization study.
    Ba Y; Shen L; Peng X; Zhang Y; Wang J · Medicine · 2024
    Methods validation study201,019 participantsHair Health forVitamin C
  27. Alterations of plasma antioxidants and mitochondrial DNA mutation in hair follicles of smokers.
    Liu CS; Chen HW; Lii CK; Tsai CS; Kuo CL; Wei YH · Environmental and molecular mutagenesis · 2002
    Observational studyHair Health forVitamin C
  28. Removal of synthetic hair dye using formamidine sulfinic acid and other sulfinate precursors.
    Hawkes JA; Lewis DM; Mama J; Murray J · International journal of cosmetic science · 2026
    Methods validation studyHair Health forVitamin C
  29. A Zinc Sulphate-Resistant Acrodermatitis Enteropathica Patient with a Novel Mutation in SLC39A4 Gene.
    Kilic M; Taskesen M; Coskun T; Gürakan F; Tokatli A; Sivri HS; Dursun A; Schmitt S; Küry S · JIMD reports · 2013
    Case reportHair Health forVitamin C
  30. The effects of minoxidil, 1% pyrithione zinc and a combination of both on hair density: a randomized controlled trial.
    Berger RS; Fu JL; Smiles KA; Turner CB; Schnell BM; Werchowski KM; Lammers KM · The British journal of dermatology · 2003
    Randomized trial200 participantsHair Health forZinc
  31. Incubatory environment of the scalp impacts pre-emergent hair to affect post-emergent hair cuticle integrity.
    Schwartz JR; Henry JP; Kerr KM; Flagler MJ; Page SH; Redman-Furey N · Journal of cosmetic dermatology · 2018
    Randomized trialHair Health forZinc
  32. A comparison of hair quality and cosmetic acceptance following the use of two anti-dandruff shampoos.
    Draelos ZD; Kenneally DC; Hodges LT; Billhimer W; Copas M; Margraf C · The journal of investigative dermatology. Symposium proceedings · 2006
    Randomized trial40 participantsHair Health forZinc
  33. BMI and levels of zinc, copper in hair, serum and urine of Turkish male patients with androgenetic alopecia.
    Ozturk P; Kurutas E; Ataseven A; Dokur N; Gumusalan Y; Gorur A; Tamer L; Inaloz S · Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) · 2015
    Case-control study216 participantsHair Health forZinc
  34. Analysis of serum zinc and copper concentrations in hair loss.
    Kil MS; Kim CW; Kim SS · Annals of dermatology · 2013
    Case-control study342 participantsHair Health forZinc
  35. Lysine-fortified wheat flour improves the nutritional and immunological status of wheat-eating families in northern China.
    Zhao W; Zhai F; Zhang D; An Y; Liu Y; He Y; Ge K; Scrimshaw NS · Food and nutrition bulletin · 2004
    Clinical trial264 participantsImmunity forLysine
  36. Success of L-lysine therapy in frequently recurrent herpes simplex infection. Treatment and prophylaxis
    R S Griffith, D E Walsh, K H Myrmel, R W Thompson, A Behforooz · Dermatologica · 1987
    Non-randomized trial52 participantsImmunity forLysine
  37. Effects of omega-3 fatty acids on hyper-inflammatory response and clinical outcomes in critically ill patients: a meta-analysis.
    Liu T; Wang X; Wang XH; Wang C; Cai JZ; Wang HF · Intensive & critical care nursing · 2025
    Meta-analysis3,152 participants41 studies pooledImmunity forOmega-3
  38. Effect of ω-3 polyunsaturated fatty acid-supplemented parenteral nutrition on inflammatory and immune function in postoperative patients with gastrointestinal malignancy: A meta-analysis of randomized control trials in China.
    Zhao Y; Wang C · Medicine · 2018
    Meta-analysis1,008 participants16 studies pooledImmunity forOmega-3
  39. Effects of omega-3 fatty acids on patients undergoing surgery for gastrointestinal malignancy: a systematic review and meta-analysis.
    Yu J; Liu L; Zhang Y; Wei J; Yang F · BMC cancer · 2017
    Meta-analysis623 participants9 studies pooledImmunity forOmega-3
  40. Omega-3 PUFA supplementation and the response to evoked endotoxemia in healthy volunteers.
    Ferguson JF; Mulvey CK; Patel PN; Shah RY; Doveikis J; Zhang W; Tabita-Martinez J; Terembula K; Eiden M; Koulman A; Griffin JL; Mehta NN; Shah R; Propert KJ; Song WL; Reilly MP · Molecular nutrition & food research · 2015
    Randomized trial60 participantsImmunity forOmega-3
  41. Omega-3 fatty acid supplementation during pregnancy and respiratory symptoms in children.
    Escamilla-Nuñez MC; Barraza-Villarreal A; Hernández-Cadena L; Navarro-Olivos E; Sly PD; Romieu I · Chest · 2014
    Randomized trial1,094 participantsImmunity forOmega-3
  42. Effects of selenium supplementation on selenoprotein gene expression and response to influenza vaccine challenge: a randomised controlled trial.
    Goldson AJ; Fairweather-Tait SJ; Armah CN; Bao Y; Broadley MR; Dainty JR; Furniss C; Hart DJ; Teucher B; Hurst R · PloS one · 2011
    Randomized trial119 participantsImmunity forSelenium
  43. Effect of selenium on immune response against hepatitis B vaccine with accelerated method in insulin-dependent diabetes mellitus patients.
    Janbakhsh A; Mansouri F; Vaziri S; Sayad B; Afsharian M; Rahimi M; Shahebrahimi K; Salari F · Caspian journal of internal medicine · 2013
    Randomized trial62 participantsImmunity forSelenium
  44. Chemoprevention trial of human hepatitis with selenium supplementation in China.
    Yu SY; Li WG; Zhu YJ; Yu WP; Hou C · Biological trace element research · 1990
    Non-randomized trial20,847 participantsImmunity forSelenium
  45. Selenium nanoparticles as adjunctive therapy in sepsis: A pilot randomized clinical trial.
    Gu WJ; Huang W; Zhao FZ; Yuan XK; Jin K; Chen JL; Zhang CY; Huang Y; He L; Zhuang H; Yin HY; Chen T · Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy · 2026
    Randomized trial70 participantsImmunity forSelenium
  46. Selenium supplementation in patients with autoimmune thyroiditis decreases thyroid peroxidase antibodies concentrations.
    Gärtner R; Gasnier BC; Dietrich JW; Krebs B; Angstwurm MW · The Journal of clinical endocrinology and metabolism · 2002
    Randomized trial70 participantsImmunity forSelenium
  47. Depressed immune response to tetanus in children with vitamin A deficiency.
    Semba RD; Muhilal; Scott AL; Natadisastra G; Wirasasmita S; Mele L; Ridwan E; West KP; Sommer A · The Journal of nutrition · 1992
    Randomized trial236 participantsImmunity forVitamin A
  48. Impact of a single megadose of vitamin A at delivery on breastmilk of mothers and morbidity of their infants.
    Roy SK; Islam A; Molla A; Akramuzzaman SM; Jahan F; Fuchs G · European journal of clinical nutrition · 1997
    Randomized trial50 participantsImmunity forVitamin A
  49. Vitamin A supplementation reduces measles morbidity in young African children: a randomized, placebo-controlled, double-blind trial.
    Coutsoudis A; Broughton M; Coovadia HM · The American journal of clinical nutrition · 1991
    Randomized trial60 participantsImmunity forVitamin A
  50. Vitamin A supplementation enhances specific IgG antibody levels and total lymphocyte numbers while improving morbidity in measles.
    Coutsoudis A; Kiepiela P; Coovadia HM; Broughton M · The Pediatric infectious disease journal · 1992
    Randomized trial60 participantsImmunity forVitamin A
  51. Vitamin A supplementation reduces the monocyte chemoattractant protein-1 intestinal immune response of Mexican children.
    Long KZ; Santos JI; Estrada Garcia T; Haas M; Firestone M; Bhagwat J; Dupont HL; Hertzmark E; Rosado JL; Nanthakumar NN · The Journal of nutrition · 2006
    Randomized trial127 participantsImmunity forVitamin A
  52. Vitamin C and contribution to the normal function of the immune system: evaluation of a health claim pursuant to Article 14 of Regulation (EC) No 1924/2006.
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusImmunity forVitamin C
  53. Therapeutic effects of high-dose vitamin C supplementation in patients with COVID-19: a meta-analysis.
    Sun L; Zhao JH; Fan WY; Feng B; Liu WW; Chen RQ; Ban C; Dang AG; Wang M; Luo KT; Zhou GY; Yu FF; Ba Y · Nutrition reviews · 2024
    Meta-analysis2,334 participants14 studies pooledImmunity forVitamin C
  54. Effect of micronutrient supplements on influenza and other respiratory tract infections among adults: a systematic review and meta-analysis.
    Abioye AI; Bromage S; Fawzi W · BMJ global health · 2021
    Meta-analysisImmunity forVitamin C
  55. New evidence for antioxidant properties of vitamin C.
    Vojdani A; Bazargan M; Vojdani E; Wright J · Cancer detection and prevention · 2001
    Randomized trial20 participantsImmunity forVitamin C
  56. Enhanced Vitamin C Delivery: A Systematic Literature Review Assessing the Efficacy and Safety of Alternative Supplement Forms in Healthy Adults.
    Calder PC; Kreider RB; McKay DL · Nutrients · 2025
    Systematic review13 studies pooledImmunity forVitamin C
  57. Vitamin D supplementation to prevent acute respiratory infections: individual participant data meta-analysis.
    Martineau AR; Jolliffe DA; Greenberg L; Aloia JF; Bergman P; Dubnov-Raz G; Esposito S; Ganmaa D; Ginde AA; Goodall EC; Grant CC; Janssens W; Jensen ME; Kerley CP; Laaksi I; Manaseki-Holland S; Mauger D; Murdoch DR; Neale R; Rees JR; Simpson S; Stelmach I; Trilok Kumar G; Urashima M; Camargo CA; Griffiths CJ; Hooper RL · Health technology assessment (Winchester, England) · 2020
    Meta-analysis11,321 participants25 studies pooledImmunity forVitamin D
  58. Association Between Vitamin D and Influenza: Meta-Analysis and Systematic Review of Randomized Controlled Trials.
    Zhu Z; Zhu X; Gu L; Zhan Y; Chen L; Li X · Frontiers in nutrition · 2022
    Meta-analysis4,859 participants10 studies pooledImmunity forVitamin D
  59. Vitamin D3 and deconvoluting a rash.
    Ernst MK; Evans ST; Techner JM; Rothbaum RM; Christensen LF; Onay UV; Biyashev D; Demczuk MM; Nguyen CV; Honda KS; McCormick TS; Tsoi LC; Gudjonsson JE; Cooper KD; Lu KQ · JCI insight · 2023
    Randomized trial28 participantsImmunity forVitamin D
  60. Effect of vitamin D3 supplementation on cellular immunity and inflammatory markers in COVID-19 patients admitted to the ICU.
    Bychinin MV; Klypa TV; Mandel IA; Yusubalieva GM; Baklaushev VP; Kolyshkina NA; Troitsky AV · Scientific reports · 2022
    Randomized trial110 participantsImmunity forVitamin D
  61. Current opinion on the role of vitamin D supplementation in respiratory infections and asthma/COPD exacerbations: A need to establish publication guidelines for overcoming the unpublished data.
    Anitua E; Tierno R; Alkhraisat MH · Clinical nutrition (Edinburgh, Scotland) · 2022
    Meta-analysis50,554 participants65 studies pooledImmunity forVitamin D
  62. Nutrient supplementation for prevention of viral respiratory tract infections in healthy subjects: A systematic review and meta-analysis.
    Vlieg-Boerstra B; de Jong N; Meyer R; Agostoni C; De Cosmi V; Grimshaw K; Milani GP; Muraro A; Oude Elberink H; Pali-Schöll I; Roduit C; Sasaki M; Skypala I; Sokolowska M; van Splunter M; Untersmayr E; Venter C; O'Mahony L; Nwaru BI · Allergy · 2022
    Meta-analysis199,055 participants115 studies pooledImmunity forZinc
  63. Zinc supplementation reduces the incidence of acute lower respiratory infections in infants and preschool children: a double-blind, controlled trial.
    Sazawal S; Black RE; Jalla S; Mazumdar S; Sinha A; Bhan MK · Pediatrics · 1998
    Randomized trial609 participantsImmunity forZinc
  64. A randomized controlled trial of zinc supplementation in the treatment of acute respiratory tract infection in Thai children.
    Rerksuppaphol S; Rerksuppaphol L · Pediatric reports · 2020
    Randomized trial64 participantsImmunity forZinc
  65. The effect of zinc and vitamin A supplementation on immune response in an older population.
    Fortes C; Forastiere F; Agabiti N; Fano V; Pacifici R; Virgili F; Piras G; Guidi L; Bartoloni C; Tricerri A; Zuccaro P; Ebrahim S; Perucci CA · Journal of the American Geriatrics Society · 1998
    Randomized trial136 participantsImmunity forZinc
  66. The role of specific nutrients in preventing immune system and blood cell disorders: an umbrella review.
    Vecchietti A; Strano P; Minutolo G; Grieco V; Cappuccio G; Granvillano G; Confalonieri L; Briganti GL; Raso E; Chimienti M; Pellegrini M; Mercogliano M; Spatari G; Lugli C; Urbano T; Lorenzon A · Journal of preventive medicine and hygiene · 2026
    Systematic review13 studies pooledImmunity forZinc
  67. Acute selenium toxicity associated with a dietary supplement.
    MacFarquhar JK; Broussard DL; Melstrom P; Hutchinson R; Wolkin A; Martin C; Burk RF; Dunn JR; Green AL; Hammond R; Schaffner W; Jones TF · Archives of internal medicine · 2010
    Observational study201 participantsNail Health forSelenium
  68. Vitamin C Deficiency in Inflammatory Bowel Disease: The Forgotten Micronutrient.
    Dunleavy KA; Ungaro RC; Manning L; Gold S; Novak J; Colombel JF · Crohn's & colitis 360 · 2023
    Other20 participantsNail Health forVitamin C
  69. Vitamins and minerals: their role in nail health and disease.
    Scheinfeld N; Dahdah MJ; Scher R · Journal of drugs in dermatology : JDD · 2007
    Narrative reviewNail Health forZinc
  70. Noninferiority of Copper Dressings Than Negative Pressure Wound Therapy in Healing Diabetic Wounds: A Randomized Clinical Trial.
    Melamed E; Dabbah J; Israel T; Kan I; Pinzur MS; Roth T; Borkow G · Advances in wound care · 2026
    Randomized trialSkin Health forCopper
  71. Improvement of facial skin characteristics using copper oxide containing pillowcases: a double-blind, placebo-controlled, parallel, randomized study.
    Borkow G; Gabbay J; Lyakhovitsky A; Huszar M · International journal of cosmetic science · 2010
    Randomized trial57 participantsSkin Health forCopper
  72. Radially Electrospun Fibrous Membrane Incorporated with Copper Peroxide Nanodots Capable of Self-Catalyzed Chemodynamic Therapy for Angiogenesis and Healing Acceleration of Diabetic Wounds.
    Huang Y; Qi L; Liu Z; Jiang Y; Wang J; Liu L; Li Y; Zhang L; Feng G · ACS applied materials & interfaces · 2023
    Animal experimentSkin Health forCopper
  73. Engineering copper nanoparticle/polysaccharide-immobilized cotton gauze for accelerated healing of Staphylococcus aureus-infected dermal wounds.
    Sahoo M; Banerjee T; Virkar S; Das S; Biswas S; Mitra D · Journal of materials chemistry. B · 2026
    Animal experimentSkin Health forCopper
  74. Stimulation of Healing of Non-Infected Stagnated Diabetic Wounds by Copper Oxide-Impregnated Wound Dressings.
    Melamed E; Rovitsky A; Roth T; Assa L; Borkow G · Medicina (Kaunas, Lithuania) · 2021
    Single-arm trialSkin Health forCopper
  75. Dietetic intervention in psoriatic arthritis: the DIETA trial.
    Leite BF; Morimoto MA; Gomes CMF; Klemz BNC; Genaro PS; Shivappa N; Hébert JR; Damasceno NRT; Pinheiro MM · Advances in rheumatology (London, England) · 2022
    Randomized trial97 participantsSkin Health forOmega-3
  76. Omega-3 fatty acid supplement skin cancer prophylaxis in lung transplant recipients: A randomized, controlled pilot trial.
    Miura K; Vail A; Chambers D; Hopkins PM; Ferguson L; Grant M; Rhodes LE; Green AC · The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · 2019
    Randomized trial49 participantsSkin Health forOmega-3
  77. Clinical and metabolic response to flaxseed oil omega-3 fatty acids supplementation in patients with diabetic foot ulcer: A randomized, double-blind, placebo-controlled trial.
    Soleimani Z; Hashemdokht F; Bahmani F; Taghizadeh M; Memarzadeh MR; Asemi Z · Journal of diabetes and its complications · 2018
    Randomized trial60 participantsSkin Health forOmega-3
  78. Treatment of hard-to-heal wounds in ischaemic lower extremities with a novel fish skin-derived matrix.
    Lee YJ; Han HJ; Shim HS · Journal of wound care · 2024
    Randomized trial50 participantsSkin Health forOmega-3
  79. Effect of eicosapentaenoic acid, an omega-3 polyunsaturated fatty acid, on UVR-related cancer risk in humans. An assessment of early genotoxic markers.
    Rhodes LE; Shahbakhti H; Azurdia RM; Moison RM; Steenwinkel MJ; Homburg MI; Dean MP; McArdle F; Beijersbergen van Henegouwen GM; Epe B; Vink AA · Carcinogenesis · 2003
    Randomized trial42 participantsSkin Health forOmega-3
  80. Comparative clinical trial of bifonazole solution versus selenium sulphide shampoo in the treatment of pityriasis versicolor.
    Chu AC · Dermatologica · 1985
    Randomized trial38 participantsSkin Health forSelenium
  81. Selenium supplementation and secondary prevention of nonmelanoma skin cancer in a randomized trial.
    Duffield-Lillico AJ; Slate EH; Reid ME; Turnbull BW; Wilkins PA; Combs GF; Park HK; Gross EG; Graham GF; Stratton MS; Marshall JR; Clark LC; Nutritional Prevention of Cancer Study Group · Journal of the National Cancer Institute · 2003
    Randomized trial1,312 participantsSkin Health forSelenium
  82. Evidence-Based Nutritional Interventions in Wound Care.
    Saeg F; Orazi R; Bowers GM; Janis JE · Plastic and reconstructive surgery · 2021
    Systematic review2,339 participants36 studies pooledSkin Health forSelenium Skin Health forZinc
  83. A randomized, double-blind placebo-controlled trial evaluating the effects of vitamin E and selenium on arsenic-induced skin lesions in Bangladesh.
    Verret WJ; Chen Y; Ahmed A; Islam T; Parvez F; Kibriya MG; Graziano JH; Ahsan H · Journal of occupational and environmental medicine · 2006
    Randomized trial121 participantsSkin Health forSelenium
  84. The Whitening, Moisturizing, Anti-aging Activities, and Skincare Evaluation of Selenium-Enriched Mung Bean Fermentation Broth.
    Wei K; Guo C; Zhu J; Wei Y; Wu M; Huang X; Zhang M; Li J; Wang X; Wang Y; Wei X · Frontiers in nutrition · 2022
    Clinical trial31 participantsSkin Health forSelenium
  85. Evaluation of the anti-wrinkle effect of an ascorbic acid-loaded dissolving microneedle patch via a double-blind, placebo-controlled clinical study.
    Lee C; Yang H; Kim S; Kim M; Kang H; Kim N; An S; Koh J; Jung H · International journal of cosmetic science · 2017
    Randomized trial23 participantsSkin Health forVitamin C
  86. Comparative Study on the Outcome of Periorbital Wrinkles Treated with Laser-Assisted Delivery of Vitamin C or Vitamin C Plus Growth Factors: A Randomized, Double-blind, Clinical Trial.
    Machado BHB; Frame J; Zhang J; Najlah M · Aesthetic plastic surgery · 2021
    Randomized trial149 participantsSkin Health forVitamin C
  87. Randomized trial of topical ascorbic acid in DMSO versus imiquimod for the treatment of basal cell carcinoma.
    Burke B; Bailie JE · Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2022
    Randomized trial25 participantsSkin Health forVitamin C
  88. Vitamin C improves healing of foot ulcers: a randomised, double-blind, placebo-controlled trial.
    Gunton JE; Girgis CM; Lau T; Vicaretti M; Begg L; Flood V · The British journal of nutrition · 2022
    Randomized trial16 participantsSkin Health forVitamin C
  89. Dietary nutrient intakes and skin-aging appearance among middle-aged American women.
    Cosgrove MC; Franco OH; Granger SP; Murray PG; Mayes AE · The American journal of clinical nutrition · 2007
    Cross-sectional study4,025 participantsSkin Health forVitamin C
  90. Sex-related differences in response to zinc pyrithione shampoo vs. non-anti-dandruff shampoo.
    Collins LZ; Baines FL; Matheson JR; Turner GA; Diao Y; Li Y; Pi Y · International journal of cosmetic science · 2019
    Meta-analysis2,088 participants20 studies pooledSkin Health forZinc
  91. Maintenance of an Acidic Skin Surface with a Novel Zinc Lactobionate Emollient Preparation Improves Skin Barrier Function in Patients with Atopic Dermatitis.
    Andrew PV; Pinnock A; Poyner A; Brown K; Chittock J; Kay LJ; Cork MJ; Danby SG · Dermatology and therapy · 2024
    Cohort study23 participantsSkin Health forZinc
  92. Spatial expression of metallothionein, matrix metalloproteinase-1 and Ki-67 in human epidermal wounds treated with zinc and determined by quantitative immunohistochemistry: A randomised double-blind trial.
    Ågren MS; Chafranska L; Eriksen JO; Forman JL; Bjerrum MJ; Schjerling P; Larsen HF; Cottarelli E; Jorgensen LN; Gjerdrum LMR · European journal of cell biology · 2021
    Randomized trial30 participantsSkin Health forZinc
  93. A pilot trial using topical regular crystalline insulin vs. aqueous zinc solution for uncomplicated cutaneous wound healing: Impact on quality of life.
    Attia EA; Belal DM; El Samahy MH; El Hamamsy MH · Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society · 2014
    Randomized trial90 participantsSkin Health forZinc
  94. Efficacy of selenium and/or N-acetyl-cysteine for improving semen parameters in infertile men: a double-blind, placebo controlled, randomized study.
    Safarinejad MR; Safarinejad S · The Journal of urology · 2009
    Randomized trial468 participantsTestosterone Support forSelenium
  95. The association between metal exposure and semen quality in Chinese males: The mediating effect of androgens.
    Liu P; Yuan G; Zhou Q; Liu Y; He X; Zhang H; Guo Y; Wen Y; Huang S; Ke Y; Chen J · Environmental pollution (Barking, Essex : 1987) · 2020
    Cross-sectional study1,136 participantsTestosterone Support forSelenium
  96. In utero and peripubertal metals exposure in relation to reproductive hormones and sexual maturation and progression among girls in Mexico City.
    Ashrap P; Sánchez BN; Téllez-Rojo MM; Basu N; Tamayo-Ortiz M; Peterson KE; Meeker JD; Watkins DJ · Environmental research · 2019
    Observational study132 participantsTestosterone Support forSelenium
  97. Relationship between serum levels of testosterone, zinc and selenium in infertile males attending fertility clinic in Nnewi, south east Nigeria.
    Oluboyo AO; Adijeh RU; Onyenekwe CC; Oluboyo BO; Mbaeri TC; Odiegwu CN; Chukwuma GO; Onwuasoanya UF · African journal of medicine and medical sciences · 2013
    Observational studyTestosterone Support forSelenium
  98. EVALUATION OF MALE SEX HORMONES AND TRACE ELEMENTS IN MALE TYPE 2 DIABETIC PATIENTS ATTENDING NNAMDI AZIKIWE UNIVERSITY TEACHING HOSPITAL DIABETIC CLINICS.
    Ubajaka CF; Meludu SC; Dioka CE; Onah CE; Osuji CU; Modebe IA; Ifeadike GC; Okwara JE; Amah UK; Nnebue CC · Nigerian journal of medicine : journal of the National Association of Resident Doctors of Nigeria · 2015
    Cross-sectional studyTestosterone Support forSelenium
  99. Effect of Two Different Doses of Vitamin D Supplementation on Metabolic Profiles of Insulin-Resistant Patients with Polycystic Ovary Syndrome.
    Jamilian M; Foroozanfard F; Rahmani E; Talebi M; Bahmani F; Asemi Z · Nutrients · 2018
    Randomized trial90 participantsTestosterone Support forVitamin D
  100. Androgens and hirsutism score of overweight women with polycystic ovary syndrome improved after vitamin D treatment: A randomized placebo controlled clinical trial.
    Al-Bayyari N; Al-Domi H; Zayed F; Hailat R; Eaton A · Clinical nutrition (Edinburgh, Scotland) · 2021
    Randomized trial60 participantsTestosterone Support forVitamin D
  101. Association between plasma 25-OH vitamin D and testosterone levels in men.
    Nimptsch K; Platz EA; Willett WC; Giovannucci E · Clinical endocrinology · 2012
    Case-control study1,362 participantsTestosterone Support forVitamin D
  102. Causal Link Between Vitamin D and Total Testosterone in Men: A Mendelian Randomization Analysis.
    Chen C; Zhai H; Cheng J; Weng P; Chen Y; Li Q; Wang C; Xia F; Wang N; Lu Y · The Journal of clinical endocrinology and metabolism · 2020
    Other4,254 participantsTestosterone Support forVitamin D
  103. Associations of vitamin D status and vitamin D-related polymorphisms with sex hormones in older men.
    Rafiq R; van Schoor NM; Sohl E; Zillikens MC; Oosterwerff MM; Schaap L; Lips P; de Jongh RT · The Journal of steroid biochemistry and molecular biology · 2017
    Cohort study643 participantsTestosterone Support forVitamin D
  104. Environmental exposure to metals and male reproductive hormones: circulating testosterone is inversely associated with blood molybdenum.
    Meeker JD; Rossano MG; Protas B; Padmanahban V; Diamond MP; Puscheck E; Daly D; Paneth N; Wirth JJ · Fertility and sterility · 2010
    Cross-sectional study219 participantsTestosterone Support forZinc
  105. Nonpharmacological Interventions for the Management of Testosterone and Sperm Parameters: A Scoping Review.
    Santos HO; Cadegiani FA; Forbes SC · Clinical therapeutics · 2022
    Scoping reviewTestosterone Support forZinc
  106. Zinc is an Essential Element for Male Fertility: A Review of Zn Roles in Men's Health, Germination, Sperm Quality, and Fertilization.
    Fallah A; Mohammad-Hasani A; Colagar AH · Journal of reproduction & infertility · 2020
    Narrative reviewTestosterone Support forZinc
  107. Clinical, endocrinological and biochemical effects of zinc deficiency.
    Prasad AS · Clinics in endocrinology and metabolism · 1986
    Narrative reviewTestosterone Support forZinc
  108. Clinical, endocrinologic, and biochemical effects of zinc deficiency.
    Prasad AS · Special topics in endocrinology and metabolism · 1986
    Narrative reviewTestosterone Support forZinc
  109. What did we learn in 35 years of research on nutrition and supplements for age-related macular degeneration: a systematic review.
    Pameijer EM; Heus P; Damen JAA; Spijker R; Hooft L; Ringens PJ; Imhof SM; van Leeuwen R · Acta ophthalmologica · 2023
    Systematic review27 studies pooledVision Support forCopper
  110. Dietary Nutrient Intake and Progression to Late Age-Related Macular Degeneration in the Age-Related Eye Disease Studies 1 and 2.
    Agrón E; Mares J; Clemons TE; Swaroop A; Chew EY; Keenan TDL; AREDS and AREDS2 Research Groups · Ophthalmology · 2021
    Cohort study8,242 participantsVision Support forCopper
  111. Association between late age-related macular degeneration and dietary intake of copper, iron, zinc and selenium: a 2005-2008 NHANES cross-sectional observational study.
    Lu Y; Li C; Liu Y; Wu T; Lu P · BMC ophthalmology · 2025
    Observational study4,996 participantsVision Support forCopper
  112. Associations between dietary nutrient intake and the risk of multiple age-related ocular diseases: evidence from longitudinal analysis.
    Yang Y; Zou H · The journal of nutrition, health & aging · 2026
    Cohort study103,192 participantsVision Support forCopper
  113. Dietary habits and dietary nutrient intake in patients with age-related macular degeneration: A case-control study.
    Šalková Kráľová J; Kolář P; Kapounová Z; Veselý P; Derflerová Brázdová Z · Central European journal of public health · 2023
    Case-control study151 participantsVision Support forCopper
  114. Efficacy and safety of AZR-MD-001 selenium sulfide ophthalmic ointment in adults with meibomian gland dysfunction: A vehicle-controlled, randomized clinical trial.
    Watson SL; Jones LW; Stapleton F; Hinds M; Ng A; Tan J; Alster Y; Bosworth C; Rafaeli O; DePuy V; CELESTIAL STUDY Group · The ocular surface · 2026
    Randomized trial245 participantsVision Support forSelenium
  115. Efficacy and safety of AZR-MD-001 selenium sulfide ophthalmic ointment in adults with meibomian gland dysfunction over six months of treatment: A Phase 2, vehicle-controlled, randomized extension trial.
    Downie LE; Craig JP; Stapleton F; Tan J; Jones LW; Ng A; Hinds M; Bosworth C; Alster Y · The ocular surface · 2025
    Randomized trial245 participantsVision Support forSelenium
  116. AZR-MD-001 0.5% selenium sulfide ophthalmic ointment for the treatment of contact lens discomfort: A vehicle-controlled, randomized, clinical trial.
    Stapleton F; Hinds M; Tan J; Jones L; Chalmers R; Bosworth C; Alster Y · The ocular surface · 2025
    Randomized trial67 participantsVision Support forSelenium
  117. The effect of a biweekly novel selenium sulfide-containing topical treatment in symptomatic contact lens wearers: An exploratory study.
    Stapleton F; Jia T; DePuy V; Bosworth C; Gleeson M; Tan J · The ocular surface · 2025
    Randomized trial14 participantsVision Support forSelenium
  118. A randomized trial of vitamin A and vitamin E supplementation for retinitis pigmentosa.
    Berson EL; Rosner B; Sandberg MA; Hayes KC; Nicholson BW; Weigel-DiFranco C; Willett W · Archives of ophthalmology (Chicago, Ill. : 1960) · 1993
    Randomized trial601 participantsVision Support forVitamin A
  119. Efficacy and safety of retinol palmitate ophthalmic solution in the treatment of dry eye: a Japanese Phase II clinical trial.
    Toshida H; Funaki T; Ono K; Tabuchi N; Watanabe S; Seki T; Otake H; Kato T; Ebihara N; Murakami A · Drug design, development and therapy · 2018
    Randomized trial66 participantsVision Support forVitamin A
  120. Vitamin A supplementation for preventing morbidity and mortality in children from six months to five years of age.
    Imdad A; Mayo-Wilson E; Haykal MR; Regan A; Sidhu J; Smith A; Bhutta ZA · The Cochrane database of systematic reviews · 2022
    Meta-analysis1,223,856 participants47 studies pooledVision Support forVitamin A
  121. Vitamin A supplementation improves retinal function in infants at risk of retinopathy of prematurity.
    Mactier H; McCulloch DL; Hamilton R; Galloway P; Bradnam MS; Young D; Lavy T; Farrell L; Weaver LT · The Journal of pediatrics · 2012
    Randomized trial89 participantsVision Support forVitamin A
  122. Effect of short-term, high-dose retinol on dark adaptation in aging and early age-related maculopathy.
    Owsley C; McGwin G; Jackson GR; Heimburger DC; Piyathilake CJ; Klein R; White MF; Kallies K · Investigative ophthalmology & visual science · 2006
    Randomized trial104 participantsVision Support forVitamin A
  123. Antioxidant vitamin and mineral supplements for age-related macular degeneration.
    Evans JR · The Cochrane database of systematic reviews · 2002
    Systematic review170 participants7 studies pooledVision Support forZinc
  124. Antioxidant vitamin and mineral supplements for slowing the progression of age-related macular degeneration.
    Evans JR; Lawrenson JG · The Cochrane database of systematic reviews · 2023
    Meta-analysis3,790 participants5 studies pooledVision Support forZinc
  125. Oral zinc in macular degeneration.
    Newsome DA; Swartz M; Leone NC; Elston RC; Miller E · Archives of ophthalmology (Chicago, Ill. : 1960) · 1988
    Randomized trial151 participantsVision Support forZinc
  126. A randomized, placebo-controlled, clinical trial of high-dose supplementation with vitamins C and E, beta carotene, and zinc for age-related macular degeneration and vision loss: AREDS report no. 8.
    Age-Related Eye Disease Study Research Group · Archives of ophthalmology (Chicago, Ill. : 1960) · 2001
    Randomized trial3,640 participantsVision Support forZinc
  127. Effect of vitamin A and zinc supplementation on the nutriture of children in Northeast Thailand.
    Udomkesmalee E; Dhanamitta S; Sirisinha S; Charoenkiatkul S; Tuntipopipat S; Banjong O; Rojroongwasinkul N; Kramer TR; Smith JC · The American journal of clinical nutrition · 1992
    Randomized trial133 participantsVision Support forZinc