Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.
- Three-year low-dose menaquinone-7 supplementation helps decrease bone loss in healthy postmenopausal women.
Knapen MH; Drummen NE; Smit E; Vermeer C; Theuwissen E · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2014
Randomized trial244 participantsflagBone Health forscienceVitamin K
- Comparison of concurrent treatment with vitamin K2 and risedronate compared with treatment with risedronate alone in patients with osteoporosis: Japanese Osteoporosis Intervention Trial-03.
Tanaka S; Miyazaki T; Uemura Y; Miyakawa N; Gorai I; Nakamura T; Fukunaga M; Ohashi Y; Ohta H; Mori S; Hagino H; Hosoi T; Sugimoto T; Itoi E; Orimo H; Shiraki M · Journal of bone and mineral metabolism · 2018
Randomized trial1,874 participantsflagBone Health forscienceVitamin K
- Investigating the interrelationship of vitamin K and vitamin D status on bone density: results from the VITamin D and OmegA-3 TriaL.
Chou SH; Booth SL; Cook NR; Kim E; Kotler G; Fu X; Buring JE; Manson JE; LeBoff MS · JBMR plus · 2026
Randomized trial771 participantsflagBone Health forscienceVitamin K
- Associations of dietary calcium intake with metabolic syndrome and bone mineral density among the Korean population: KNHANES 2008-2011.
Kim MK; Chon SJ; Noe EB; Roh YH; Yun BH; Cho S; Choi YS; Lee BS; Seo SK · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2018
Cross-sectional study14,705 participantsflagBone Health forscienceCalcium
- Calcium supplementation during pregnancy and maternal and offspring bone health: a systematic review and meta-analysis.
Tihtonen K; Korhonen P; Isojärvi J; Ojala R; Ashorn U; Ashorn P; Tammela O · Annals of the New York Academy of Sciences · 2022
Meta-analysis1,566 participants7 studies pooledflagBone Health forscienceCalcium
- An update on magnesium and bone health.
Rondanelli M; Faliva MA; Tartara A; Gasparri C; Perna S; Infantino V; Riva A; Petrangolini G; Peroni G · Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2022
Narrative reviewflagBone Health forscienceMagnesium
- Magnesium intake, bone mineral density, and fractures: results from the Women's Health Initiative Observational Study.
Orchard TS; Larson JC; Alghothani N; Bout-Tabaku S; Cauley JA; Chen Z; LaCroix AZ; Wactawski-Wende J; Jackson RD · The American journal of clinical nutrition · 2014
Cohort study73,684 participantsflagBone Health forscienceMagnesium
- Effect of dietary boron on mineral, estrogen, and testosterone metabolism in postmenopausal women.
Nielsen FH; Hunt CD; Mullen LM; Hunt JR · FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 1987
Single-arm trial12 participantsflagBone Health forscienceBoron
- Effects of boron supplementation on bone mineral density and dietary, blood, and urinary calcium, phosphorus, magnesium, and boron in female athletes.
Meacham SL; Taper LJ; Volpe SL · Environmental health perspectives · 1995
Randomized trial28 participantsflagBone Health forscienceBoron
- [Comparative study of the urinary excretion of boron, calcium, magnesium and phosphorus in postmenopausal women with and without osteoporosis].
José Ramón V; Mora Mora M; Marino Alarcón O; Hernández G; Josefina Linares L; Urdaneta Romero H; Arévalo González E · Investigacion clinica · 2013
Case-control study45 participantsflagBone Health forscienceBoron
- The relationship between boron and magnesium status and bone mineral density in the human: a review.
Volpe SL; Taper LJ; Meacham S · Magnesium research · 1994
Narrative reviewflagBone Health forscienceBoron
- Metabolic responses of postmenopausal women to supplemental dietary boron and aluminum during usual and low magnesium intake: boron, calcium, and magnesium absorption and retention and blood mineral concentrations
C D Hunt, J L Herbel, F H Nielsen · The American Journal of Clinical Nutrition · 1997
Non-randomized trial11 participantsflagBone Health forscienceBoron
- What is the impact of daily oral supplementation of vitamin D3 (cholecalciferol) plus calcium on the incidence of hip fracture in older people? A systematic review and meta-analysis.
Manoj P; Derwin R; George S · International journal of older people nursing · 2023
Meta-analysis12,620 participants7 studies pooledflagBone Health forscienceCalcium
- Calcium supplementation prevents seasonal bone loss and changes in biochemical markers of bone turnover in elderly New England women: a randomized placebo-controlled trial.
Storm D; Eslin R; Porter ES; Musgrave K; Vereault D; Patton C; Kessenich C; Mohan S; Chen T; Holick MF; Rosen CJ · The Journal of clinical endocrinology and metabolism · 1998
Randomized trial60 participantsflagBone Health forscienceCalcium
- The effects of calcium supplementation (milk powder or tablets) and exercise on bone density in postmenopausal women.
Prince R; Devine A; Dick I; Criddle A; Kerr D; Kent N; Price R; Randell A · Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 1995
Randomized trial168 participantsflagBone Health forscienceCalcium
- The efficacy of calcium supplementation alone in elderly Thai women over a 2-year period: a randomized controlled trial.
Rajatanavin R; Chailurkit L; Saetung S; Thakkinstian A; Nimitphong H · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2014
Randomized trial404 participantsflagBone Health forscienceCalcium
- Calcium-enriched foods and bone mass growth in prepubertal girls: a randomized, double-blind, placebo-controlled trial.
Bonjour JP; Carrie AL; Ferrari S; Clavien H; Slosman D; Theintz G; Rizzoli R · The Journal of clinical investigation · 1997
Randomized trial149 participantsflagBone Health forscienceCalcium
- Association between Serum Magnesium and Fractures: A Systematic Review and Meta-Analysis of Observational Studies.
Dominguez LJ; Veronese N; Ciriminna S; Pérez-Albela JL; Vásquez-López VF; Rodas-Regalado S; Di Bella G; Parisi A; Tagliaferri F; Barbagallo M · Nutrients · 2023
Meta-analysis119,755 participants4 studies pooledflagBone Health forscienceMagnesium
- Bioabsorbable Magnesium-Based Materials Potential and Safety in Bone Surgery: A Systematic Review.
Hung CH; Kwok YC; Yip J; Wong HH; Leung YY · Craniomaxillofacial trauma & reconstruction · 2025
Systematic review386 participants8 studies pooledflagBone Health forscienceMagnesium
- Vascularized bone grafting fixed by biodegradable magnesium screw for treating osteonecrosis of the femoral head.
Zhao D; Huang S; Lu F; Wang B; Yang L; Qin L; Yang K; Li Y; Li W; Wang W; Tian S; Zhang X; Gao W; Wang Z; Zhang Y; Xie X; Wang J; Li J · Biomaterials · 2016
Randomized trial48 participantsflagBone Health forscienceMagnesium
- Sex-specific differences in the association of magnesium intake with femoral neck bone mineral density among older adults.
Wang B; Tan X; Yao X; Zhu Z · Endocrine connections · 2025
Cross-sectional study1,343 participantsflagBone Health forscienceMagnesium
- Pregnancy vitamin D supplementation and offspring bone mineral density in childhood follow-up of a randomized controlled trial.
Moon RJ; D' Angelo S; Curtis EM; Ward KA; Crozier SR; Schoenmakers I; Javaid MK; Bishop NJ; Godfrey KM; Cooper C; Harvey NC; MAVIDOS Trial Group · The American journal of clinical nutrition · 2024
Randomized trial454 participantsflagBone Health forscienceVitamin D
- Vitamin D analogs and bone: preclinical and clinical studies with eldecalcitol.
Matsumoto T; Takano T; Saito H; Takahashi F · BoneKEy reports · 2014
Narrative reviewflagBone Health forscienceVitamin D
- Efficacy of vitamin D fortified foods on bone mineral density and serum bone biomarkers: A systematic review and meta-analysis of interventional studies.
Tangestani H; Djafarian K; Emamat H; Arabzadegan N; Shab-Bidar S · Critical reviews in food science and nutrition · 2020
Meta-analysis1,786 participants20 studies pooledflagBone Health forscienceVitamin D
- Cholecalciferol Supplementation Attenuates Bone Loss in Incident Kidney Transplant Recipients: A Prespecified Secondary Endpoint Analysis of a Randomized Controlled Trial.
Tsujita M; Doi Y; Obi Y; Hamano T; Tomosugi T; Futamura K; Okada M; Hiramitsu T; Goto N; Isaka Y; Takeda A; Narumi S; Watarai Y · Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2022
Randomized trial193 participantsflagBone Health forscienceVitamin D
- Vitamin D supplementation and bone health in post-menopausal women: a 24-month randomized controlled intervention with enhanced bioavailability formulations.
Rasool N; Munir Y · European journal of clinical nutrition · 2026
Randomized trial612 participantsflagBone Health forscienceVitamin D
- Vitamin K and the prevention of fractures: systematic review and meta-analysis of randomized controlled trials.
Cockayne S; Adamson J; Lanham-New S; Shearer MJ; Gilbody S; Torgerson DJ · Archives of internal medicine · 2006
Meta-analysis13 studies pooledflagBone Health forscienceVitamin K
- Effect of combined administration of vitamin D3 and vitamin K2 on bone mineral density of the lumbar spine in postmenopausal women with osteoporosis.
Iwamoto J; Takeda T; Ichimura S · Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association · 2001
Randomized trial92 participantsflagBone Health forscienceVitamin K
- Efficacy and safety of vitamin K2 for postmenopausal women with osteoporosis at a long-term follow-up: meta-analysis and systematic review.
Zhou M; Han S; Zhang W; Wu D · Journal of bone and mineral metabolism · 2022
Meta-analysis6,853 participants9 studies pooledflagBone Health forscienceVitamin K
- Low-dose vitamin K2 (MK-4) supplementation for 12 months improves bone metabolism and prevents forearm bone loss in postmenopausal Japanese women.
Koitaya N; Sekiguchi M; Tousen Y; Nishide Y; Morita A; Yamauchi J; Gando Y; Miyachi M; Aoki M; Komatsu M; Watanabe F; Morishita K; Ishimi Y · Journal of bone and mineral metabolism · 2015
Randomized trial48 participantsflagBone Health forscienceVitamin K
- Increased incidence of fractures in middle-aged and elderly men with low intakes of phosphorus and zinc.
Elmståhl S; Gullberg B; Janzon L; Johnell O; Elmståhl B · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 1999
Cohort study6,576 participantsflagBone Health forscienceZinc
- Zinc Supplementation Increases Procollagen Type 1 Amino-Terminal Propeptide in Premenarcheal Girls: A Randomized Controlled Trial.
Berger PK; Pollock NK; Laing EM; Chertin V; Bernard PJ; Grider A; Shapses SA; Ding KH; Isales CM; Lewis RD · The Journal of nutrition · 2016
Randomized trial147 participantsflagBone Health forscienceZinc
- Randomized controlled trial of prenatal zinc supplementation and fetal bone growth.
Merialdi M; Caulfield LE; Zavaleta N; Figueroa A; Costigan KA; Dominici F; Dipietro JA · The American journal of clinical nutrition · 2004
Randomized trial242 participantsflagBone Health forscienceZinc
- The effects of zinc supplementation on serum zinc, alkaline phosphatase activity and fracture healing of bones.
Sadighi A; Roshan MM; Moradi A; Ostadrahimi A · Saudi medical journal · 2009
Randomized trial60 participantsflagBone Health forscienceZinc
- Is Zinc an Important Trace Element on Bone-Related Diseases and Complications? A Meta-analysis and Systematic Review from Serum Level, Dietary Intake, and Supplementation Aspects.
Ceylan MN; Akdas S; Yazihan N · Biological trace element research · 2021
Meta-analysis40 studies pooledflagBone Health forscienceZinc
- Circulating and dietary magnesium and risk of cardiovascular disease: a systematic review and meta-analysis of prospective studies.
Del Gobbo LC; Imamura F; Wu JH; de Oliveira Otto MC; Chiuve SE; Mozaffarian D · The American journal of clinical nutrition · 2013
Meta-analysis313,041 participants16 studies pooledflagCardiovascular Support forscienceMagnesium
- Magnesium and the risk of cardiovascular events: a meta-analysis of prospective cohort studies.
Qu X; Jin F; Hao Y; Li H; Tang T; Wang H; Yan W; Dai K · PloS one · 2013
Meta-analysis532,979 participants19 studies pooledflagCardiovascular Support forscienceMagnesium
- Quantitative Association Between Serum/Dietary Magnesium and Cardiovascular Disease/Coronary Heart Disease Risk: A Dose-Response Meta-analysis of Prospective Cohort Studies.
Zhao L; Hu M; Yang L; Xu H; Song W; Qian Y; Zhao M · Journal of cardiovascular pharmacology · 2020
Meta-analysis544,581 participants18 studies pooledflagCardiovascular Support flagHeart Health forscienceMagnesium
- Comparative Efficacy of Nutraceuticals on Endothelial Function: A Systematic Review and Network Meta-Analysis.
Norouzzadeh M; Rashedi MH; Mahdavi-Mazdeh G; Kosari A; Shahinfar H · Current atherosclerosis reports · 2026
Meta-analysisflagCardiovascular Support flagHeart Health forscienceMagnesium
- Serum magnesium, mortality, and cardiovascular disease in chronic kidney disease and end-stage renal disease patients: a systematic review and meta-analysis.
Xiong J; He T; Wang M; Nie L; Zhang Y; Wang Y; Huang Y; Feng B; Zhang J; Zhao J · Journal of nephrology · 2020
Meta-analysis200,934 participants20 studies pooledflagCardiovascular Support forscienceMagnesium
- Vitamin K Intake and Atherosclerotic Cardiovascular Disease in the Danish Diet Cancer and Health Study.
Bellinge JW; Dalgaard F; Murray K; Connolly E; Blekkenhorst LC; Bondonno CP; Lewis JR; Sim M; Croft KD; Gislason G; Torp-Pedersen C; Tjønneland A; Overvad K; Hodgson JM; Schultz C; Bondonno NP · Journal of the American Heart Association · 2021
Cohort study53,372 participantsflagCardiovascular Support forscienceVitamin K
- Menaquinone-7 supplementation improves arterial stiffness in healthy postmenopausal women. A double-blind randomised clinical trial.
Knapen MH; Braam LA; Drummen NE; Bekers O; Hoeks AP; Vermeer C · Thrombosis and haemostasis · 2016
Randomized trial244 participantsflagCardiovascular Support forscienceVitamin K
- Effects of One-Year Menaquinone-7 Supplementation on Vascular Stiffness and Blood Pressure in Post-Menopausal Women.
de Vries F; Bittner R; Maresz K; Machuron F; Gåserød O; Jeanne JF; Schurgers LJ · Nutrients · 2025
Randomized trial165 participantsflagCardiovascular Support forscienceVitamin K
- Dietary Vitamin K1 Intake and Incident Aortic Valve Stenosis.
Schultz CJ; Dalgaard F; Bellinge JW; Murray K; Sim M; Connolly E; Blekkenhorst LC; Bondonno CP; Lewis JR; Gislason GH; Tjønneland A; Overvad K; Hodgson JM; Bondonno NP · Arteriosclerosis, thrombosis, and vascular biology · 2024
Cohort study55,545 participantsflagCardiovascular Support forscienceVitamin K
- Association between vitamin K1 intake and mortality in the Danish Diet, Cancer, and Health cohort.
Palmer CR; Bellinge JW; Dalgaard F; Sim M; Murray K; Connolly E; Blekkenhorst LC; Bondonno CP; Croft KD; Gislason G; Tjønneland A; Overvad K; Schultz C; Lewis JR; Hodgson JM; Bondonno NP · European journal of epidemiology · 2021
Cohort study56,048 participantsflagCardiovascular Support forscienceVitamin K
- Efficacy of oral magnesium therapy in the treatment of chronic constipation in spastic cerebral palsy children: a randomized controlled trial.
Hassanein SMA; Deifallah SM; Bastawy HA · World journal of pediatrics : WJP · 2021
Randomized trial100 participantsflagDigestive Health forscienceMagnesium
- Ca:Mg ratio, medium-chain fatty acids, and the gut microbiome.
Fan L; Zhu X; Sun S; Yu C; Huang X; Ness R; Dugan LL; Shu L; Seidner DL; Murff HJ; Fodor AA; Azcarate-Peril MA; Shrubsole MJ; Dai Q · Clinical nutrition (Edinburgh, Scotland) · 2022
Randomized trial240 participantsflagDigestive Health forscienceMagnesium
- The Magnesium-Rich Formula for Functional Constipation in Infants: a Randomized Comparator-Controlled Study.
Benninga MA; MENA Infant Constipation Study Group; Vandenplas Y · Pediatric gastroenterology, hepatology & nutrition · 2022
Randomized trial286 participantsflagDigestive Health forscienceMagnesium
- A Randomized Double-blind Placebo-controlled Trial on the Effect of Magnesium Oxide in Patients With Chronic Constipation.
Mori S; Tomita T; Fujimura K; Asano H; Ogawa T; Yamasaki T; Kondo T; Kono T; Tozawa K; Oshima T; Fukui H; Kimura T; Watari J; Miwa H · Journal of neurogastroenterology and motility · 2022
Randomized trial34 participantsflagDigestive Health forscienceMagnesium
- Magnesium treatment increases gut microbiome synthesizing vitamin D and inhibiting colorectal cancer: results from a double-blind precision-based randomized placebo-controlled trial.
Sun E; Zhu X; Ness RM; Murff HJ; Sun S; Yu C; Fan L; Azcarate-Peril MA; Shrubsole MJ; Dai Q · The American journal of clinical nutrition · 2025
Randomized trial240 participantsflagDigestive Health forscienceMagnesium
- Magnesium-L-threonate improves sleep quality and daytime functioning in adults with self-reported sleep problems: A randomized controlled trial.
Hausenblas HA; Lynch T; Hooper S; Shrestha A; Rosendale D; Gu J · Sleep medicine: X · 2025
Randomized trial80 participantsflagEnergy forscienceMagnesium
- Total magnesium intake and risk of frailty in older women.
Struijk EA; Fung TT; Bischoff-Ferrari HA; Willett WC; Lopez-Garcia E · Journal of cachexia, sarcopenia and muscle · 2024
Cohort study81,524 participantsflagEnergy forscienceMagnesium
- Red blood cell magnesium and chronic fatigue syndrome.
Cox IM; Campbell MJ; Dowson D · Lancet (London, England) · 1991
Randomized trial32 participantsflagEnergy forscienceMagnesium
- Exercise, magnesium and immune function.
Laires MJ; Monteiro C · Magnesium research · 2008
Narrative reviewflagEnergy forscienceMagnesium
- Effect of Vitamin D Supplementation on Fatigue in Multiple Sclerosis: A Systematic Review and Meta-Analysis.
López-Muñoz P; Torres-Costoso AI; Fernández-Rodríguez R; Guzmán-Pavón MJ; de Arenas-Arroyo SN; Basco-López JÁ; Reina-Gutiérrez S · Nutrients · 2023
Meta-analysis345 participants5 studies pooledflagEnergy forscienceVitamin D
- Vitamin D Supplementation in Adolescents and Young Adults With Juvenile Systemic Lupus Erythematosus for Improvement in Disease Activity and Fatigue Scores: A Randomized, Double-Blind, Placebo-Controlled Trial.
Lima GL; Paupitz J; Aikawa NE; Takayama L; Bonfa E; Pereira RM · Arthritis care & research · 2016
Randomized trial40 participantsflagEnergy forscienceVitamin D
- Vitamin D in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome After COVID-19 or Vaccination: A Randomized Controlled Trial.
Kodama S; Nakata M; Konishi N; Yoshino M; Fujisawa A; Naganuma M; Kobayashi Y; Hirai Y; Kitagawa A; Miyokawa M; Mishima R; Teramukai S; Fukushima M · Nutrients · 2026
Randomized trial91 participantsflagEnergy forscienceVitamin D
- The effects of vitamin D supplementation on disease activity and fatigue in Libyan rheumatoid arthritis patients.
Elfituri S · Reumatologia · 2024
Randomized trial68 participantsflagEnergy forscienceVitamin D
- The effect of home-based aerobic training and vitamin D supplementation on fatigue and quality of life in patients with multiple sclerosis during COVID-19 outbreak.
Bahmani E; Hoseini R; Amiri E · Science & sports · 2022
Randomized trial40 participantsflagEnergy forscienceVitamin D
- Effects of boron supplementation on the severity and duration of pain in primary dysmenorrhea.
Nikkhah S; Dolatian M; Naghii MR; Zaeri F; Taheri SM · Complementary therapies in clinical practice · 2015
Randomized trial113 participantsflagGeneral Health forscienceBoron
- Efficacy and safety of tavaborole topical solution, 5%, a novel boron-based antifungal agent, for the treatment of toenail onychomycosis: Results from 2 randomized phase-III studies.
Elewski BE; Aly R; Baldwin SL; González Soto RF; Rich P; Weisfeld M; Wiltz H; Zane LT; Pollak R · Journal of the American Academy of Dermatology · 2015
Randomized trialflagGeneral Health forscienceBoron
- The efficacy and safety of tavaborole, a novel, boron-based pharmaceutical agent: phase 2 studies conducted for the topical treatment of toenail onychomycosis.
Toledo-Bahena ME; Bucko A; Ocampo-Candiani J; Herz-Ruelas ME; Jones TM; Jarratt MT; Pollak RA; Zane LT · Journal of drugs in dermatology : JDD · 2015
Clinical trial336 participantsflagGeneral Health forscienceBoron
- Boron neutron capture therapy (BNCT) for glioblastoma multiforme: a phase II study evaluating a prolonged high-dose of boronophenylalanine (BPA).
Henriksson R; Capala J; Michanek A; Lindahl SA; Salford LG; Franzén L; Blomquist E; Westlin JE; Bergenheim AT; Swedish Brain Tumour Study Group · Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology · 2009
Single-arm trial30 participantsflagGeneral Health forscienceBoron
- Effects of Calcium Fructoborate on Levels of C-Reactive Protein, Total Cholesterol, Low-Density Lipoprotein, Triglycerides, IL-1β, IL-6, and MCP-1: a Double-blind, Placebo-controlled Clinical Study
Otilia-Constantina Rogoveanu, George Dan Mogosanu, Cornelia Bejenaru, Ludovic Everard Bejenaru, Octavian Croitoru, Johny Neamtu, Zbigniew Pietrzkowski, Tania Reyes-Izquierdo, Andrei Bita, Iulia Daria Scorei, Romulus Ion Scorei · Biological Trace Element Research · 2015
Randomized trial78 participantsflagGeneral Health forscienceBoron
- Perioperative systemic magnesium to minimize postoperative pain: a meta-analysis of randomized controlled trials.
De Oliveira GS; Castro-Alves LJ; Khan JH; McCarthy RJ · Anesthesiology · 2013
Meta-analysis1,257 participants20 studies pooledflagGeneral Health forscienceMagnesium
- Long-term outcome after intravenous magnesium sulphate in suspected acute myocardial infarction: the second Leicester Intravenous Magnesium Intervention Trial (LIMIT-2).
Woods KL; Fletcher S · Lancet (London, England) · 1994
Randomized trial2,316 participantsflagGeneral Health forscienceMagnesium
- Association of magnesium sulfate use with mortality in critically ill patients with sepsis: a retrospective propensity score-matched cohort study.
Gu WJ; Duan XJ; Liu XZ; Cen Y; Tao LY; Lyu J; Yin HY · British journal of anaesthesia · 2023
Cohort study10,999 participantsflagGeneral Health forscienceMagnesium
- Hypomagnesemia and Mortality in Incident Hemodialysis Patients.
Li L; Streja E; Rhee CM; Mehrotra R; Soohoo M; Brunelli SM; Kovesdy CP; Kalantar-Zadeh K · American journal of kidney diseases : the official journal of the National Kidney Foundation · 2016
Cohort study9,359 participantsflagGeneral Health forscienceMagnesium
- The effects of magnesium supplementation on abnormal uterine bleeding, alopecia, quality of life, and acne in women with polycystic ovary syndrome: a randomized clinical trial.
Jaripur M; Ghasemi-Tehrani H; Askari G; Gholizadeh-Moghaddam M; Clark CCT; Rouhani MH · Reproductive biology and endocrinology : RB&E · 2022
Randomized trial64 participantsflagGeneral Health forscienceMagnesium
- Vitamin D supplementation for prevention of mortality in adults.
Bjelakovic G; Gluud LL; Nikolova D; Whitfield K; Wetterslev J; Simonetti RG; Bjelakovic M; Gluud C · The Cochrane database of systematic reviews · 2014
Meta-analysis95,286 participants159 studies pooledflagGeneral Health forscienceVitamin D
- Effect of vitamin D on gastrointestinal symptoms and health-related quality of life in irritable bowel syndrome patients: a randomized double-blind clinical trial.
Abbasnezhad A; Amani R; Hajiani E; Alavinejad P; Cheraghian B; Ghadiri A · Neurogastroenterology and motility · 2018
Randomized trial90 participantsflagGeneral Health forscienceVitamin D
- The impact of vitamin D administration on mortality in COVID-19 patients: a systematic review and meta-analysis of randomized controlled trials.
Kow CS; Ramachandram DS; Hasan SS; Wong Z; Thiruchelvam K · Inflammopharmacology · 2024
Meta-analysis2,495 participants19 studies pooledflagGeneral Health forscienceVitamin D
- Vitamin D Status and Mortality: A Systematic Review of Observational Studies.
Heath AK; Kim IY; Hodge AM; English DR; Muller DC · International journal of environmental research and public health · 2019
Systematic review84 studies pooledflagGeneral Health forscienceVitamin D
- Meta-analysis of long-term vitamin D supplementation on overall mortality.
Zheng Y; Zhu J; Zhou M; Cui L; Yao W; Liu Y · PloS one · 2014
Meta-analysis42 studies pooledflagGeneral Health forscienceVitamin D
- Dietary vitamin K intake associates with reduced all-cause mortality in non-alcoholic fatty liver disease patients.
Huang Y; Zhu X; Han L; Hu H · Scientific reports · 2025
Cohort study7,857 participantsflagGeneral Health forscienceVitamin K
- Vitamin K status, cardiovascular disease, and all-cause mortality: a participant-level meta-analysis of 3 US cohorts.
Shea MK; Barger K; Booth SL; Matuszek G; Cushman M; Benjamin EJ; Kritchevsky SB; Weiner DE · The American journal of clinical nutrition · 2020
Meta-analysis3,891 participants3 studies pooledflagGeneral Health forscienceVitamin K
- The Effect of Topical Vitamin K1 on the Treatment of Cetuximab-Induced Skin Rashes in Metastatic Colorectal Cancer Patients.
Roayaei M; Rezaei M; Najafizade N · Advanced biomedical research · 2024
Randomized trial49 participantsflagGeneral Health forscienceVitamin K
- Effect of vitamin K on improving post‑kidney transplant outcomes: a meta‑analysis.
Sun Z; Zhu K; Liang G; Yan F; Chao S; Jia L; Niu Y · Experimental and therapeutic medicine · 2023
Meta-analysis7 studies pooledflagGeneral Health forscienceVitamin K
- Vitamin K1 intake is associated with lower risk for all-cause and cardiovascular disease mortality in community-dwelling older Australian women.
Dupuy M; Radavelli-Bagatini S; Zhong L; Dalla Via J; Zhu K; Blekkenhorst LC; Bondonno NP; Linneberg A; Bellinge JW; Schultz C; Courtney W; Prince RL; Hodgson JM; Lewis JR; Sim M · Nutrition, metabolism, and cardiovascular diseases : NMCD · 2024
Cohort study1,436 participantsflagGeneral Health forscienceVitamin K
- Effectiveness of sodium bicarbonate and zinc chloride mouthwashes in the treatment of oral mucositis and quality of life in patients with cancer under chemotherapy.
Mohammadi F; Oshvandi K; Kamallan SR; Khazaei S; Ranjbar H; Ahmadi-Motamayel F; Gillespie M; Jenabi E; Vafaei SY · Nursing open · 2022
Randomized trial144 participantsflagGeneral Health forscienceZinc
- Zinc supplementation in young children with acute diarrhea in India.
Sazawal S; Black RE; Bhan MK; Bhandari N; Sinha A; Jalla S · The New England journal of medicine · 1995
Randomized trial937 participantsflagGeneral Health forscienceZinc
- Associations of mortality with ocular disorders and an intervention of high-dose antioxidants and zinc in the Age-Related Eye Disease Study: AREDS Report No. 13.
Clemons TE; Kurinij N; Sperduto RD; AREDS Research Group · Archives of ophthalmology (Chicago, Ill. : 1960) · 2004
Randomized trial4,753 participantsflagGeneral Health forscienceZinc
- Effects of zinc and probiotic co-supplementation on inflammation, gastrointestinal symptoms, quality of life, and mood in irritable bowel syndrome patients.
Rezazadegan M; Soheilipour M; Amani R · Scientific reports · 2026
Randomized trial84 participantsflagGeneral Health forscienceZinc
- Effect of zinc sulfate supplementation on premenstrual syndrome and health-related quality of life: Clinical randomized controlled trial.
Siahbazi S; Behboudi-Gandevani S; Moghaddam-Banaem L; Montazeri A · The journal of obstetrics and gynaecology research · 2018
Randomized trial142 participantsflagGeneral Health forscienceZinc
- Effects of magnesium supplementation on improving hyperglycemia, hypercholesterolemia, and hypertension in type 2 diabetes: A pooled analysis of 24 randomized controlled trials.
Xu L; Li X; Wang X; Xu M · Frontiers in nutrition · 2023
Meta-analysis1,325 participants24 studies pooledflagHeart Health forscienceMagnesium
- The effect of lowering blood pressure by magnesium supplementation in diabetic hypertensive adults with low serum magnesium levels: a randomized, double-blind, placebo-controlled clinical trial.
Guerrero-Romero F; Rodríguez-Morán M · Journal of human hypertension · 2009
Randomized trial82 participantsflagHeart Health forscienceMagnesium
- Positive effects of magnesium supplementation in metabolic syndrome.
Kisters S; Kisters K; Werner T; Vormann J; Tokmak F; Westhoff T; Gröber U; Predel HG; Reuter H · International journal of clinical pharmacology and therapeutics · 2024
Randomized trial54 participantsflagHeart Health forscienceMagnesium
- Predictive Model of Nail Consistency Using Scanning Electron Microscopy with Energy-Dispersive X-Ray.
Mingorance Álvarez E; Martínez Quintana R; Pérez Pico AM; Mayordomo R · Biology · 2021
Cross-sectional study57 participantsflagNail Health forscienceCalcium
- Vitamin C Deficiency in Inflammatory Bowel Disease: The Forgotten Micronutrient.
Dunleavy KA; Ungaro RC; Manning L; Gold S; Novak J; Colombel JF · Crohn's & colitis 360 · 2023
Other20 participantsflagNail Health forscienceVitamin C
- Vitamins and minerals: their role in nail health and disease.
Scheinfeld N; Dahdah MJ; Scher R · Journal of drugs in dermatology : JDD · 2007
Narrative reviewflagNail Health forscienceZinc
- Role of magnesium supplementation in the treatment of depression: A randomized clinical trial.
Tarleton EK; Littenberg B; MacLean CD; Kennedy AG; Daley C · PloS one · 2017
Randomized trial126 participantsflagStress Relief forscienceMagnesium
- Effects of Intravenous Esketamine or Magnesium Sulfate on Early Postoperative Negative Emotions and Pain in Patients Undergoing Endoscopic Sinus Surgery: A Randomized Controlled Trial.
Wang L; Zhou J; Liu Q; Qian K; Wang L; Xie C · Therapeutics and clinical risk management · 2026
Randomized trial137 participantsflagStress Relief forscienceMagnesium
- Effect of short-term magnesium supplementation on anxiety, depression and sleep quality in patients after open-heart surgery.
Saba S; Faizi F; Sepandi M; Nehrir B · Magnesium research · 2022
Non-randomized trial60 participantsflagStress Relief forscienceMagnesium
- Effects of dry needling compared to magnesium infiltration in trigger points for patients with myofascial pain syndrome: a randomized controlled study in Tunisia.
Dhouibi J; Moncer R; Kalbousi N; Gaddour M; Laayouni S; Ouanes W; Kacem B; Jemni S · Korean journal of family medicine · 2026
Randomized trial45 participantsflagStress Relief forscienceMagnesium
- Effect of magnesium and vitamin B6 supplementation on mental health and quality of life in stressed healthy adults: Post-hoc analysis of a randomised controlled trial.
Noah L; Dye L; Bois De Fer B; Mazur A; Pickering G; Pouteau E · Stress and health : journal of the International Society for the Investigation of Stress · 2021
Randomized trialflagStress Relief forscienceMagnesium
- Biochemical and physiologic consequences of boron deprivation in humans.
Nielsen FH · Environmental health perspectives · 1995
Single-arm trial12 participantsflagTestosterone Support forscienceBoron
- Plasma boron and the effects of boron supplementation in males.
Green NR; Ferrando AA · Environmental health perspectives · 1995
Randomized trial19 participantsflagTestosterone Support forscienceBoron
- Comparative effects of daily and weekly boron supplementation on plasma steroid hormones and proinflammatory cytokines
Mohammad Reza Naghii, Mahmoud Mofid, Ali Reza Asgari, Mehdi Hedayati, Maryam-Saddat Daneshpour · Journal of Trace Elements in Medicine and Biology · 2011
Non-randomized trial8 participantsflagTestosterone Support forscienceBoron
- Magnesium and anabolic hormones in older men.
Maggio M; Ceda GP; Lauretani F; Cattabiani C; Avantaggiato E; Morganti S; Ablondi F; Bandinelli S; Dominguez LJ; Barbagallo M; Paolisso G; Semba RD; Ferrucci L · International journal of andrology · 2012
Cohort study399 participantsflagTestosterone Support forscienceMagnesium
- Analysis of the relationship between the blood concentration of several metals, macro- and micronutrients and endocrine disorders associated with male aging.
Rotter I; Kosik-Bogacka DI; Dołęgowska B; Safranow K; Kuczyńska M; Laszczyńska M · Environmental geochemistry and health · 2017
Cross-sectional study313 participantsflagTestosterone Support forscienceMagnesium
- Effect of magnesium supplementation in improving hyperandrogenism, hirsutism, and sleep quality in women with polycystic ovary syndrome: A randomized, placebo-controlled clinical trial.
Gholizadeh-Moghaddam M; Ghasemi-Tehrani H; Askari G; Jaripur M; Clark CCT; Rouhani MH · Health science reports · 2024
Randomized trial64 participantsflagTestosterone Support forscienceMagnesium
- The effects of trace element supplementation on glycolipid metabolism in PCOS: a systematic review and meta-analysis.
Yang L; Gao Y; Zhao W; Qi Y; Duo X; Wang H · Frontiers in nutrition · 2025
Meta-analysis1,600 participants25 studies pooledflagTestosterone Support forscienceMagnesium
- Effects of magnesium supplementation on testosterone levels of athletes and sedentary subjects at rest and after exhaustion.
Cinar V; Polat Y; Baltaci AK; Mogulkoc R · Biological trace element research · 2011
Non-randomized trial20 participantsflagTestosterone Support forscienceMagnesium
- Effect of Two Different Doses of Vitamin D Supplementation on Metabolic Profiles of Insulin-Resistant Patients with Polycystic Ovary Syndrome.
Jamilian M; Foroozanfard F; Rahmani E; Talebi M; Bahmani F; Asemi Z · Nutrients · 2018
Randomized trial90 participantsflagTestosterone Support forscienceVitamin D
- Androgens and hirsutism score of overweight women with polycystic ovary syndrome improved after vitamin D treatment: A randomized placebo controlled clinical trial.
Al-Bayyari N; Al-Domi H; Zayed F; Hailat R; Eaton A · Clinical nutrition (Edinburgh, Scotland) · 2021
Randomized trial60 participantsflagTestosterone Support forscienceVitamin D
- Association between plasma 25-OH vitamin D and testosterone levels in men.
Nimptsch K; Platz EA; Willett WC; Giovannucci E · Clinical endocrinology · 2012
Case-control study1,362 participantsflagTestosterone Support forscienceVitamin D
- Causal Link Between Vitamin D and Total Testosterone in Men: A Mendelian Randomization Analysis.
Chen C; Zhai H; Cheng J; Weng P; Chen Y; Li Q; Wang C; Xia F; Wang N; Lu Y · The Journal of clinical endocrinology and metabolism · 2020
Other4,254 participantsflagTestosterone Support forscienceVitamin D
- Associations of vitamin D status and vitamin D-related polymorphisms with sex hormones in older men.
Rafiq R; van Schoor NM; Sohl E; Zillikens MC; Oosterwerff MM; Schaap L; Lips P; de Jongh RT · The Journal of steroid biochemistry and molecular biology · 2017
Cohort study643 participantsflagTestosterone Support forscienceVitamin D
- Environmental exposure to metals and male reproductive hormones: circulating testosterone is inversely associated with blood molybdenum.
Meeker JD; Rossano MG; Protas B; Padmanahban V; Diamond MP; Puscheck E; Daly D; Paneth N; Wirth JJ · Fertility and sterility · 2010
Cross-sectional study219 participantsflagTestosterone Support forscienceZinc
- Nonpharmacological Interventions for the Management of Testosterone and Sperm Parameters: A Scoping Review.
Santos HO; Cadegiani FA; Forbes SC · Clinical therapeutics · 2022
Scoping reviewflagTestosterone Support forscienceZinc
- Zinc is an Essential Element for Male Fertility: A Review of Zn Roles in Men's Health, Germination, Sperm Quality, and Fertilization.
Fallah A; Mohammad-Hasani A; Colagar AH · Journal of reproduction & infertility · 2020
Narrative reviewflagTestosterone Support forscienceZinc
- Clinical, endocrinological and biochemical effects of zinc deficiency.
Prasad AS · Clinics in endocrinology and metabolism · 1986
Narrative reviewflagTestosterone Support forscienceZinc
- Clinical, endocrinologic, and biochemical effects of zinc deficiency.
Prasad AS · Special topics in endocrinology and metabolism · 1986
Narrative reviewflagTestosterone Support forscienceZinc