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Multi For Her 50+ No Iron

Nature Made
4.5
★ ★ ★ ★ ★
(789 ratings)
Iodine 150 mcg
Molybdenum 75 mcg
Manganese 4 mg
Copper 2 mg
Selenium 70 mcg
Chromium 120 mcg
Vitamin K 80 mcg
Product Image
Score71
Broad iron-free coverage suits older women, though basic mineral forms, modest bone doses, and missing serving data limit confidence.
How scoring works
Quantity:0 Not Present • ( servings)
Goals:
General Health
Immunity
Detoxification

Score 71

Broad iron-free coverage suits older women, though basic mineral forms, modest bone doses, and missing serving data limit confidence.
How scoring works
$11.11($0.00 per serving)
Walmart
$ 11.11
Vitacost
$ 11.49
iHerb
$ 11.49
Report prices

Analysis

The iron-free formula offers broad vitamin and trace-mineral coverage for women over 50. D3, K1, calcium, and magnesium address several bone pathways without adding iron that may not be needed.

Magnesium oxide, zinc oxide, and other basic salts are less appealing than better-absorbed forms. Calcium and magnesium are also modest for a dedicated bone supplement.

Missing format, serving count, and cost data prevent a fair judgment of convenience and value. The formula works best as a broad multivitamin, not as a complete bone or detoxification product.

Who is it for
  • Women over 50 who do not need supplemental iron
  • Adults seeking broad daily micronutrients
Best for
  • Iron-free general nutrition
  • Foundational bone nutrient coverage

Pros

  • No added iron
  • Includes D3 and vitamin K1
  • Broad trace-mineral coverage

Cons

  • Uses basic mineral salts
  • Calcium and magnesium are modest
  • Serving and value data are missing

Warnings

  • Vitamin K1 can interfere with warfarin dosing
  • Magnesium oxide may loosen stools in sensitive users
  • Confirm the serving size before stacking another multivitamin

Nutrient quality

74 High impact

Broad coverage and an iron-free design suit the intended audience. Basic forms and modest major-mineral doses reduce nutrient quality.

Ingredient transparency

72 High impact

The active nutrient list is fully quantified and free of hidden blends. Missing serving information, directions, and non-active ingredients are major practical gaps.

Customer satisfaction

68 High impact

The aggregate rating is favorable and backed by a substantial review volume. No specific comments are available to assess recurring problems or real-world fit.

Value for money

68 High impact

Broad coverage and a focused formula suggest good basic value. Absent serving information makes true daily cost and convenience uncertain.

Report analysis

Goals

General Health
General Health
Impact
Highest effect
A+ Goal FitC+ Strength of SupportA- CoverageA Formula Quality
Folate · 665 mcg DFEVitamin B12 · 25 mcgVitamin D · 25 mcgMagnesium · 100 mgVitamin K · 80 mcgSelenium · 70 mcgZinc · 15 mgVitamin C · 180 mg

A wide vitamin and mineral profile supports nutritional gap coverage, energy metabolism, immune function, and bone health. The iron-free design may suit older women who do not need supplemental iron, while vitamin D3 and selenium provide useful maintenance coverage.

Vitamin K is supplied as K1 rather than K2, while magnesium oxide, zinc oxide, sodium selenate, and cyanocobalamin limit form quality. Several major nutrients are useful, but calcium and magnesium remain too modest to provide complete mineral coverage.

Study evidence
Magnesium Supportive 114 studies
Selenium Supportive 70 studies
Vitamin K Supportive 34 studies
Zinc Supportive 60 studies
Immunity
Immunity
Impact
Highest effect
A Goal FitC+ Strength of SupportA- CoverageA Formula Quality
Magnesium · 100 mgVitamin C · 180 mgZinc · 15 mgVitamin A · 750 mcgVitamin D · 25 mcgSelenium · 70 mcg

Vitamins A, C, and D plus zinc and selenium support barrier integrity, immune-cell function, and antioxidant defenses. The iron-free design may suit older women who do not need iron supplementation.

The breadth is useful for daily nutritional coverage, but vitamin C remains below the amount used for focused immune support. Zinc oxide and sodium selenate are less favorable forms than well-absorbed chelates or organic selenium.

Study evidence
Selenium Mixed 37 studies
Vitamin C Supportive 53 studies
Vitamin D Supportive 85 studies
Zinc Supportive 73 studies
Detoxification
Detoxification
Impact
High effect
C+ Goal FitC+ Strength of SupportB CoverageB- Formula Quality
Folate · 665 mcg DFEVitamin B12 · 25 mcgVitamin B6 · 6 mgMolybdenum · 75 mcgSelenium · 70 mcgMagnesium · 100 mgVitamin E · 27 mgZinc · 15 mgVitamin C · 180 mgRiboflavin · 1.7 mg

Molybdenum supports sulfite oxidase, while vitamin C, selenium, zinc, folate, and B vitamins support antioxidant and enzyme systems. The nutrient range provides broad foundational coverage.

The formula is a general multivitamin rather than a concentrated liver product. Basic mineral salts and conventional B-vitamin forms reduce form quality, although the molybdenum amount reaches the lower edge of a useful targeted range.

Study evidence
Folate Supportive 16 studies
Molybdenum Adverse 1 study
Selenium Supportive 10 studies
Vitamin C Supportive 9 studies
Zinc Supportive 30 studies
Bone Health
Bone Health
Impact
Moderate effect
B Goal FitD Strength of SupportC+ CoverageC- Formula Quality
Vitamin K · 80 mcgMagnesium · 100 mgCalcium · 200 mgVitamin D · 25 mcgCopper · 2 mgManganese · 4 mgZinc · 15 mgVitamin C · 180 mg

Vitamin D3, vitamin K1, calcium, magnesium, zinc, copper, and manganese cover mineralization, transport, and bone-matrix cofactors. The broad nutrient base is relevant to bone health but is not optimized as a dedicated skeletal formula.

The 200 mg calcium and magnesium amounts are modest, and carbonate, oxide, sulfate, and K1 forms are less preferred than citrate, chelates, and MK-7. Many nutrients serve general multivitamin needs, which reduces bone-specific dose depth and focus.

Study evidence
Calcium Supportive 144 studies
Copper Disputed 20 studies
Magnesium Supportive 48 studies
Manganese Adverse 12 studies
Vitamin D Supportive 202 studies
Vitamin K Supportive 78 studies
Zinc Supportive 33 studies
Energy
Essential Energy Nutrients
Energy
Impact
Moderate effect
B- Goal FitD Strength of SupportD+ CoverageB+ Formula Quality
Iodine · 150 mcgVitamin D · 25 mcgVitamin B5 · 10 mgMagnesium · 100 mgRiboflavin · 1.7 mgThiamin · 1.5 mgVitamin B12 · 25 mcg

B vitamins and iodine support normal metabolic and thyroid-related energy production. The broad multivitamin may help when fatigue reflects a nutritional shortfall.

Vitamin B12 is modest and magnesium oxide is both underdosed and poorly absorbed for focused energy support. The lack of iron removes an oxygen-transport pathway that could matter for some older women.

Study evidence
Iodine Adverse 3 studies
Magnesium Supportive 4 studies
Hair Health
Hair Health
Impact
Moderate effect
C Goal FitC- Strength of SupportC CoverageC- Formula Quality
Biotin · 30 mcgVitamin D · 25 mcgZinc · 15 mgVitamin C · 180 mg

Vitamin D, zinc, iodine, selenium, copper, biotin, and vitamin C provide broad maintenance support for hair. The iron-free formula does not address low iron stores, and biotin is modest.

Clear amounts help assessment, but several minerals use basic inorganic forms. The general multivitamin design lacks a direct structural or hormonal strategy.

Study evidence
Biotin Supportive 4 studies
Copper Adverse 4 studies
Iodine No effect 1 study
Selenium Disputed 7 studies
Vitamin C Mixed 5 studies
Vitamin D Disputed 34 studies
Zinc Supportive 22 studies

Ingredients

IngredientAmount per serving
Vitamin A (Beta-Carotene, Vitamin A Acetate)
 750 mcg
Vitamin C (Ascorbic Acid)
 180 mg
Vitamin D3 (Cholecalciferol)
 25 mcg
Vitamin E (DL-Alpha-Tocopheryl Acetate)
 27 mg
Vitamin K (Phytonadione)
 80 mcg
Thiamine (Thiamine Mononitrate)
 1.5 mg
Riboflavin
1.7 mg
Niacin (Niacinamide)
 20 mg
Vitamin B6 (Pyridoxine Hydrochloride)
 6 mg
Folate
665 mcg DFE
Vitamin B12 (Cyanocobalamin)
 25 mcg
Biotin
30 mcg
Pantothenic Acid (Calcium D-Pantothenate)
 10 mg
Calcium (Calcium Carbonate)
 200 mg
Iodine (Potassium Iodide)
 150 mcg
Magnesium (Magnesium Oxide)
 100 mg
Zinc (Zinc Oxide)
 15 mg
Selenium (Sodium Selenate)
 70 mcg
Copper (Cupric Sulfate)
 2 mg
Manganese (Manganese Sulfate)
 4 mg
Chromium (Chromium Chloride)
 120 mcg
Molybdenum (Sodium Molybdate)
 75 mcg
Gluten Free Women 50+
Report overview
Iodine (Potassium Iodide) · 150 mcg OverallScore79
A+ Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyF Value

Potassium iodide provides a stable, readily absorbed iodine source at an amount suited to routine support. A broad, calcium-containing tablet is less streamlined than a dedicated iodine product. Value cannot be judged reliably because per-serving cost is unavailable.

View ingredientView products
Molybdenum (Sodium Molybdate) · 75 mcg OverallScore58
C- Active Ingredient Quality & BioavailabilityA- Dose, Safety & Label TransparencyF Value

Sodium molybdate is a soluble form, but no branded source verifies chelation or purity standards. The 75 mcg amount reaches the lower edge of the target range and remains well below the adult upper limit. Value cannot be judged because a serving cost is not provided.

View ingredientView products
Manganese (Manganese Sulfate) · 4 mg OverallScore56
D- Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyF Value

The 4 mg dose is well aligned with the collection target and stays below the adult upper intake limit. Manganese sulfate is a less absorbable form than amino acid chelates or organic acid salts. Value cannot be judged reliably because the number of servings and per-serving cost are not provided.

View ingredientView products
Loading alternative details
85 Performance

Essential Blend Multi Mineral

Jigsaw Health
<p>Chelated zinc, selenium, copper, manganese, chromium, and molybdenum provide substantially stronger trace-mineral forms than the original’s oxide, sulfate, chloride, and selenate forms. The formula omits vitamins, calcium, and magnesium, so it is better only for someone seeking focused mineral support rather than a complete multivitamin.</p>
72 Performance

Multi Vita Min

Pure Synergy
<p>Vitamin D3, vitamin K2, natural tocopherols and tocotrienols, choline, and broad trace minerals create a more refined iron-free foundation. Many B-vitamin and mineral forms are not specified and calcium and magnesium are absent, but the overall nutrient design is stronger than the original’s conventional forms.</p>
77 Performance

Complete Multivitamin

Bayer One A Day Men's 50+
<p>The iron-free older-adult profile supplies vitamin D, vitamin K, B vitamins, iodine, selenium, chromium, and lycopene in amounts broadly comparable with the original. Most forms are undisclosed and zinc is relatively high, but the formula is closely matched to the same life stage and intended role.</p>
79 Budget

One Daily Men's 50+

21st Century
<p>The low-cost long supply covers the main vitamins and trace minerals in an iron-free formula suited to older adults. Magnesium oxide, zinc oxide, synthetic vitamin E, and relatively high zinc are trade-offs similar to or greater than those in the original.</p>
70 Budget

Daily Vits

NOW
<p>A long supply provides practical B vitamins, methylcobalamin, chelated zinc, selenium, copper, manganese, and chromium at economical daily value. Vitamin D2 and token calcium and magnesium reduce suitability for bone support, but the serving economics are clearly disclosed.</p>
77 Budget

Men's 50+ Complete Multivitamin

Bayer One A Day
<p>The long iron-free supply closely matches the original’s older-adult role and covers vitamin D, B vitamins, iodine, zinc, selenium, and chromium. Most chemical forms are not identified and zinc is relatively high, but the simple daily formula remains a practical budget option.</p>
78 Value

Multi For Him

Nature Made
<p>The once-daily formula keeps broad iron-free vitamin and trace-mineral coverage while providing a fully stated serving count and strong daily value. Calcium and magnesium remain modest and forms are conventional, but its practical disclosure is better than the original’s missing serving information.</p>
73 Value

Alive! Garden Goodness Men's Multivitamin

Nature's Way
<p>Vitamin D3, vitamin K, iodine, selenium, and a substantial fruit-and-vegetable blend provide broad iron-free coverage with useful plant content. Zinc oxide and several basic forms limit refinement, but the disclosed serving economics and focused men’s profile create a reasonable quality-to-cost balance.</p>
62 Value

BalanceBlend

Fairhaven Health
<p>Methylfolate, methylcobalamin, active riboflavin and vitamin B6, selenomethionine, and chromium picolinate improve several forms compared with the original. The hidden proprietary blend prevents a full potency check, but the broad iron-free nutrient base offers worthwhile quality for the cost when its intended use fits.</p>
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Three-year low-dose menaquinone-7 supplementation helps decrease bone loss in healthy postmenopausal women.
    Knapen MH; Drummen NE; Smit E; Vermeer C; Theuwissen E · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2014
    Randomized trial244 participantsBone Health forVitamin K
  2. Investigating the interrelationship of vitamin K and vitamin D status on bone density: results from the VITamin D and OmegA-3 TriaL.
    Chou SH; Booth SL; Cook NR; Kim E; Kotler G; Fu X; Buring JE; Manson JE; LeBoff MS · JBMR plus · 2026
    Randomized trial771 participantsBone Health forVitamin K
  3. Efficacy and safety of vitamin K2 for postmenopausal women with osteoporosis at a long-term follow-up: meta-analysis and systematic review.
    Zhou M; Han S; Zhang W; Wu D · Journal of bone and mineral metabolism · 2022
    Meta-analysis6,853 participants9 studies pooledBone Health forVitamin K
  4. What is the impact of daily oral supplementation of vitamin D3 (cholecalciferol) plus calcium on the incidence of hip fracture in older people? A systematic review and meta-analysis.
    Manoj P; Derwin R; George S · International journal of older people nursing · 2023
    Meta-analysis12,620 participants7 studies pooledBone Health forCalcium
  5. Calcium supplementation prevents seasonal bone loss and changes in biochemical markers of bone turnover in elderly New England women: a randomized placebo-controlled trial.
    Storm D; Eslin R; Porter ES; Musgrave K; Vereault D; Patton C; Kessenich C; Mohan S; Chen T; Holick MF; Rosen CJ · The Journal of clinical endocrinology and metabolism · 1998
    Randomized trial60 participantsBone Health forCalcium
  6. The effects of calcium supplementation (milk powder or tablets) and exercise on bone density in postmenopausal women.
    Prince R; Devine A; Dick I; Criddle A; Kerr D; Kent N; Price R; Randell A · Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 1995
    Randomized trial168 participantsBone Health forCalcium
  7. The efficacy of calcium supplementation alone in elderly Thai women over a 2-year period: a randomized controlled trial.
    Rajatanavin R; Chailurkit L; Saetung S; Thakkinstian A; Nimitphong H · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2014
    Randomized trial404 participantsBone Health forCalcium
  8. Calcium-enriched foods and bone mass growth in prepubertal girls: a randomized, double-blind, placebo-controlled trial.
    Bonjour JP; Carrie AL; Ferrari S; Clavien H; Slosman D; Theintz G; Rizzoli R · The Journal of clinical investigation · 1997
    Randomized trial149 participantsBone Health forCalcium
  9. The Association between Dietary and Circulating Copper Levels and Osteoporosis: a Scoping Review.
    Ju Y; Xiong W; Pang Y; Chen Z; Hou J; Zheng S; Li Z; Liu T; Xia H; Xia M; Zhong Y; Li J; Jiang X · Biological trace element research · 2026
    Scoping review18 studies pooledBone Health forCopper
  10. Association between dietary copper, iron, zinc, selenium intake and osteopenia or osteoporosis in elderly hypertensive patients: a retrospective cohort study.
    Chen M; Jia L; Gao R · Frontiers in nutrition · 2024
    Cohort study5,286 participantsBone Health forCopper
  11. Associations of dietary copper intake with total bone mineral density and lumbar spine bone mineral density in American adults.
    Hu M; Wang Z; Li C; Zheng Y; Hu J · Medicine · 2025
    Cross-sectional studyBone Health forCopper
  12. The association between dietary mineral intake and bone mineral density: a cross-sectional study.
    Wei M; Wei J; Huang S · Journal of health, population, and nutrition · 2025
    Cross-sectional study11,520 participantsBone Health forCopper
  13. Association between dietary copper intake and bone mineral density in children and adolescents aged 8-19 years: A cross-sectional study.
    Cui A; Yan J; Li H; Fan Z; Wei X; Wang H; Zhuang Y · PloS one · 2024
    Cross-sectional study6,965 participantsBone Health forCopper
  14. Association between Serum Magnesium and Fractures: A Systematic Review and Meta-Analysis of Observational Studies.
    Dominguez LJ; Veronese N; Ciriminna S; Pérez-Albela JL; Vásquez-López VF; Rodas-Regalado S; Di Bella G; Parisi A; Tagliaferri F; Barbagallo M · Nutrients · 2023
    Meta-analysis119,755 participants4 studies pooledBone Health forMagnesium
  15. Bioabsorbable Magnesium-Based Materials Potential and Safety in Bone Surgery: A Systematic Review.
    Hung CH; Kwok YC; Yip J; Wong HH; Leung YY · Craniomaxillofacial trauma & reconstruction · 2025
    Systematic review386 participants8 studies pooledBone Health forMagnesium
  16. Vascularized bone grafting fixed by biodegradable magnesium screw for treating osteonecrosis of the femoral head.
    Zhao D; Huang S; Lu F; Wang B; Yang L; Qin L; Yang K; Li Y; Li W; Wang W; Tian S; Zhang X; Gao W; Wang Z; Zhang Y; Xie X; Wang J; Li J · Biomaterials · 2016
    Randomized trial48 participantsBone Health forMagnesium
  17. An update on magnesium and bone health.
    Rondanelli M; Faliva MA; Tartara A; Gasparri C; Perna S; Infantino V; Riva A; Petrangolini G; Peroni G · Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2022
    Narrative reviewBone Health forMagnesium
  18. Sex-specific differences in the association of magnesium intake with femoral neck bone mineral density among older adults.
    Wang B; Tan X; Yao X; Zhu Z · Endocrine connections · 2025
    Cross-sectional study1,343 participantsBone Health forMagnesium
  19. Risk of Environmental Chemicals on Bone Fractures Is Independent of Low Bone Mass in US Adults: Insights from 2017 to 2018 NHANES.
    Ling R; Ai Y; Chen C; Zhang J; Zou Z; Cheng S; Li C; Li X; Wang B · Metabolites · 2023
    Cross-sectional study2,640 participantsBone Health forManganese
  20. The Manganese-Bone Connection: Investigating the Role of Manganese in Bone Health.
    Taskozhina G; Batyrova G; Umarova G; Issanguzhina Z; Kereyeva N · Journal of clinical medicine · 2024
    Narrative reviewBone Health forManganese
  21. Associations of multiple metals with bone mineral density: A population-based study in US adults.
    Wei MH; Cui Y; Zhou HL; Song WJ; Di DS; Zhang RY; Huang Q; Liu JA; Wang Q · Chemosphere · 2021
    Cross-sectional studyBone Health forManganese
  22. Sex-specific associations of urinary mixed-metal concentrations with femoral bone mineral density among older people: an NHANES (2017-2020) analysis.
    Li H; Li G; Yi M; Zhou J; Deng Y; Huang Y; He S; Meng X; Liu L · Frontiers in public health · 2024
    Cross-sectional study31 participantsBone Health forManganese
  23. Relationship between blood manganese and bone mineral density and bone mineral content in adults: A population-based cross-sectional study.
    Wang C; Zhu Y; Long H; Ou M; Zhao S · PloS one · 2022
    Cross-sectional study9,732 participantsBone Health forManganese
  24. Pregnancy vitamin D supplementation and offspring bone mineral density in childhood follow-up of a randomized controlled trial.
    Moon RJ; D' Angelo S; Curtis EM; Ward KA; Crozier SR; Schoenmakers I; Javaid MK; Bishop NJ; Godfrey KM; Cooper C; Harvey NC; MAVIDOS Trial Group · The American journal of clinical nutrition · 2024
    Randomized trial454 participantsBone Health forVitamin D
  25. Vitamin D analogs and bone: preclinical and clinical studies with eldecalcitol.
    Matsumoto T; Takano T; Saito H; Takahashi F · BoneKEy reports · 2014
    Narrative reviewBone Health forVitamin D
  26. Efficacy of vitamin D fortified foods on bone mineral density and serum bone biomarkers: A systematic review and meta-analysis of interventional studies.
    Tangestani H; Djafarian K; Emamat H; Arabzadegan N; Shab-Bidar S · Critical reviews in food science and nutrition · 2020
    Meta-analysis1,786 participants20 studies pooledBone Health forVitamin D
  27. Cholecalciferol Supplementation Attenuates Bone Loss in Incident Kidney Transplant Recipients: A Prespecified Secondary Endpoint Analysis of a Randomized Controlled Trial.
    Tsujita M; Doi Y; Obi Y; Hamano T; Tomosugi T; Futamura K; Okada M; Hiramitsu T; Goto N; Isaka Y; Takeda A; Narumi S; Watarai Y · Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2022
    Randomized trial193 participantsBone Health forVitamin D
  28. Vitamin D supplementation and bone health in post-menopausal women: a 24-month randomized controlled intervention with enhanced bioavailability formulations.
    Rasool N; Munir Y · European journal of clinical nutrition · 2026
    Randomized trial612 participantsBone Health forVitamin D
  29. Vitamin K and the prevention of fractures: systematic review and meta-analysis of randomized controlled trials.
    Cockayne S; Adamson J; Lanham-New S; Shearer MJ; Gilbody S; Torgerson DJ · Archives of internal medicine · 2006
    Meta-analysis13 studies pooledBone Health forVitamin K
  30. Effect of combined administration of vitamin D3 and vitamin K2 on bone mineral density of the lumbar spine in postmenopausal women with osteoporosis.
    Iwamoto J; Takeda T; Ichimura S · Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association · 2001
    Randomized trial92 participantsBone Health forVitamin K
  31. Low-dose vitamin K2 (MK-4) supplementation for 12 months improves bone metabolism and prevents forearm bone loss in postmenopausal Japanese women.
    Koitaya N; Sekiguchi M; Tousen Y; Nishide Y; Morita A; Yamauchi J; Gando Y; Miyachi M; Aoki M; Komatsu M; Watanabe F; Morishita K; Ishimi Y · Journal of bone and mineral metabolism · 2015
    Randomized trial48 participantsBone Health forVitamin K
  32. Increased incidence of fractures in middle-aged and elderly men with low intakes of phosphorus and zinc.
    Elmståhl S; Gullberg B; Janzon L; Johnell O; Elmståhl B · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 1999
    Cohort study6,576 participantsBone Health forZinc
  33. Zinc Supplementation Increases Procollagen Type 1 Amino-Terminal Propeptide in Premenarcheal Girls: A Randomized Controlled Trial.
    Berger PK; Pollock NK; Laing EM; Chertin V; Bernard PJ; Grider A; Shapses SA; Ding KH; Isales CM; Lewis RD · The Journal of nutrition · 2016
    Randomized trial147 participantsBone Health forZinc
  34. Randomized controlled trial of prenatal zinc supplementation and fetal bone growth.
    Merialdi M; Caulfield LE; Zavaleta N; Figueroa A; Costigan KA; Dominici F; Dipietro JA · The American journal of clinical nutrition · 2004
    Randomized trial242 participantsBone Health forZinc
  35. The effects of zinc supplementation on serum zinc, alkaline phosphatase activity and fracture healing of bones.
    Sadighi A; Roshan MM; Moradi A; Ostadrahimi A · Saudi medical journal · 2009
    Randomized trial60 participantsBone Health forZinc
  36. Is Zinc an Important Trace Element on Bone-Related Diseases and Complications? A Meta-analysis and Systematic Review from Serum Level, Dietary Intake, and Supplementation Aspects.
    Ceylan MN; Akdas S; Yazihan N · Biological trace element research · 2021
    Meta-analysis40 studies pooledBone Health forZinc
  37. Comparison of efficacy of folic acid and silymarin in the management of antiepileptic drug induced liver injury: a randomized clinical trial.
    Asgarshirazi M; Shariat M; Sheikh M · Hepatobiliary & pancreatic diseases international : HBPD INT · 2018
    Randomized trial55 participantsDetoxification forFolate
  38. Homocysteine, folate, and nonalcoholic fatty liver disease: a systematic review with meta-analysis and Mendelian randomization investigation.
    Yuan S; Chen J; Dan L; Xie Y; Sun Y; Li X; Larsson SC · The American journal of clinical nutrition · 2022
    Meta-analysis30,368 participants22 studies pooledDetoxification forFolate
  39. Serum folate levels and urinary arsenic methylation profiles in the US population: NHANES, 2003-2012.
    Zhang X; Xu X; Zhong Y; Power MC; Taylor BD; Carrillo G · Journal of exposure science & environmental epidemiology · 2020
    Cross-sectional study11,016 participantsDetoxification forFolate
  40. Association between serum folate levels and blood concentrations of cadmium and lead in US adults.
    Wu Z; Hu H; Wang C; Wu J; Xiong Y; Fu Y; Cheng X; Su H; Li P · Environmental science and pollution research international · 2022
    Cross-sectional study15,501 participantsDetoxification forFolate
  41. Effects of Folic Acid Supplementation on Liver Enzymes, Lipid Profile, and Insulin Resistance in Patients with Non-Alcoholic Fatty Liver Disease: A Randomized Controlled Trial.
    Molaqanbari MR; Zarringol S; Talari HR; Taghizadeh M; Bahmani F; Mohtashamian A; Ebrahimzadeh A; Sharifi N · Advanced biomedical research · 2023
    Randomized trial66 participantsDetoxification forFolate
  42. Human molybdenum exposure risk in industrial regions of China: New critical effect indicators and reference dose.
    Kuang HX; Li MY; Zeng XW; Chen D; Zhou Y; Zheng T; Xiang MD; Wu QZ; Chen XC; Dong GH; Yu YJ · Ecotoxicology and environmental safety · 2024
    Cross-sectional study2,267 participantsDetoxification forMolybdenum
  43. Supplementation with selenium can influence nausea, fatigue, physical, renal, and liver function of children and adolescents with cancer.
    Vieira ML; Fonseca FL; Costa LG; Beltrame RL; Chaves CM; Cartum J; Alves SI; Azzalis LA; Junqueira VB; Pereria EC; Rocha KC · Journal of medicinal food · 2015
    Randomized trialDetoxification forSelenium
  44. [Selenium and oxidative stress in cancer patients].
    Gorozhanskaia ÉG; Sviridova SP; Dobrovol'skaia MM; Zybrikhina GN; Kashnia ShR · Biomeditsinskaia khimiia · 2014
    Single-arm trial40 participantsDetoxification forSelenium
  45. Comprehensive Insights into the Health Effects of Selenium Exposure and Supplementation Among the Chinese Community Middle-Aged and Elderly: a Combined Retrospective Cohort Study and Intervention Study.
    Li C; Peng X; Zheng J; Shi K; Qin L; Yang Q; Wang Z; Liu Y; Huang L · Biological trace element research · 2024
    Other40 participantsDetoxification forSelenium
  46. Heavy metals and metalloids exposure and liver function in Chinese adults - A nationally representative cross-sectional study.
    Wang S; Lyu Y; Ji S; Liu N; Wu B; Zhao F; Li Z; Qu Y; Zhu Y; Xie L; Li Y; Zhang Z; Song H; Hu X; Qiu Y; Zheng X; Zhang W; Yang Y; Li F; Cai J; Zhu Y; Cao Z; Tan F; Shi X · Environmental research · 2024
    Cross-sectional study9,445 participantsDetoxification forSelenium
  47. Selenium-Biofortified Strawberries Improve Glucose Homeostasis and Hepatic Function: A 30-Day Randomized Controlled Trial in Healthy Adults.
    Vasto S; Di Rosa L; Ferrantelli V; Fiore AS; Giordano CP; Cannizzaro A; Sabatino L; Macaluso A; Caldarella R; Caldara GF; Baldassano S · Nutrients · 2026
    Randomized trial35 participantsDetoxification forSelenium
  48. Vitamin C supplementation ameliorates liver function profile and antiviral treatment response in Hepatitis C patients.
    Nayila I; Javed MS; Khan MA; Hussain G; Raza Naqvi SA; Ali S; Jabeen Z; Shahnawaz S; Akram R; Iman T; Hassan Dogar MZ; Malik SA · Pakistan journal of pharmaceutical sciences · 2022
    Non-randomized trial200 participantsDetoxification forVitamin C
  49. Effect of ascorbic acid-rich diet on in vivo-induced oxidative stress.
    Alleva R; Di Donato F; Strafella E; Staffolani S; Nocchi L; Borghi B; Pignotti E; Santarelli L; Tomasetti M · The British journal of nutrition · 2012
    Non-randomized trial46 participantsDetoxification forVitamin C
  50. Dietary Vitamin C Intake Is Associated With Improved Liver Function and Glucose Metabolism in Chinese Adults.
    Luo X; Zhang W; He Z; Yang H; Gao J; Wu P; Ma ZF · Frontiers in nutrition · 2022
    Observational study8,307 participantsDetoxification forVitamin C
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    Puspitasari IM; Abdulah R; Yamazaki C; Kameo S; Nakano T; Koyama H · Radiation oncology (London, England) · 2015
    Systematic review16 studies pooledGeneral Health forSelenium
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    Huang Y; Zhu X; Han L; Hu H · Scientific reports · 2025
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  76. Vitamin K status, cardiovascular disease, and all-cause mortality: a participant-level meta-analysis of 3 US cohorts.
    Shea MK; Barger K; Booth SL; Matuszek G; Cushman M; Benjamin EJ; Kritchevsky SB; Weiner DE · The American journal of clinical nutrition · 2020
    Meta-analysis3,891 participants3 studies pooledGeneral Health forVitamin K
  77. The Effect of Topical Vitamin K1 on the Treatment of Cetuximab-Induced Skin Rashes in Metastatic Colorectal Cancer Patients.
    Roayaei M; Rezaei M; Najafizade N · Advanced biomedical research · 2024
    Randomized trial49 participantsGeneral Health forVitamin K
  78. Effect of vitamin K on improving post‑kidney transplant outcomes: a meta‑analysis.
    Sun Z; Zhu K; Liang G; Yan F; Chao S; Jia L; Niu Y · Experimental and therapeutic medicine · 2023
    Meta-analysis7 studies pooledGeneral Health forVitamin K
  79. Vitamin K1 intake is associated with lower risk for all-cause and cardiovascular disease mortality in community-dwelling older Australian women.
    Dupuy M; Radavelli-Bagatini S; Zhong L; Dalla Via J; Zhu K; Blekkenhorst LC; Bondonno NP; Linneberg A; Bellinge JW; Schultz C; Courtney W; Prince RL; Hodgson JM; Lewis JR; Sim M · Nutrition, metabolism, and cardiovascular diseases : NMCD · 2024
    Cohort study1,436 participantsGeneral Health forVitamin K
  80. Effectiveness of sodium bicarbonate and zinc chloride mouthwashes in the treatment of oral mucositis and quality of life in patients with cancer under chemotherapy.
    Mohammadi F; Oshvandi K; Kamallan SR; Khazaei S; Ranjbar H; Ahmadi-Motamayel F; Gillespie M; Jenabi E; Vafaei SY · Nursing open · 2022
    Randomized trial144 participantsGeneral Health forZinc
  81. Zinc supplementation in young children with acute diarrhea in India.
    Sazawal S; Black RE; Bhan MK; Bhandari N; Sinha A; Jalla S · The New England journal of medicine · 1995
    Randomized trial937 participantsGeneral Health forZinc
  82. Associations of mortality with ocular disorders and an intervention of high-dose antioxidants and zinc in the Age-Related Eye Disease Study: AREDS Report No. 13.
    Clemons TE; Kurinij N; Sperduto RD; AREDS Research Group · Archives of ophthalmology (Chicago, Ill. : 1960) · 2004
    Randomized trial4,753 participantsGeneral Health forZinc
  83. Effects of zinc and probiotic co-supplementation on inflammation, gastrointestinal symptoms, quality of life, and mood in irritable bowel syndrome patients.
    Rezazadegan M; Soheilipour M; Amani R · Scientific reports · 2026
    Randomized trial84 participantsGeneral Health forZinc
  84. Effect of zinc sulfate supplementation on premenstrual syndrome and health-related quality of life: Clinical randomized controlled trial.
    Siahbazi S; Behboudi-Gandevani S; Moghaddam-Banaem L; Montazeri A · The journal of obstetrics and gynaecology research · 2018
    Randomized trial142 participantsGeneral Health forZinc
  85. The Role of Sesbania grandiflora-Derived Biotin and Bambusa arundinacea-Derived Silica Extracts in Promoting Hair, Skin, and Nail Health: A Randomized, Double-Blind, Placebo-Controlled Clinical Study.
    Patel MN; Maheshvari J; Patel N · Cureus · 2025
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  86. Low serum biotinidase activity in children with valproic acid monotherapy.
    Schulpis KH; Karikas GA; Tjamouranis J; Regoutas S; Tsakiris S · Epilepsia · 2001
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  87. Vitamins A, B, C, and D: A Short Review for the Dermatologist.
    Coerdt KM; Goggins CA; Khachemoune A · Alternative therapies in health and medicine · 2021
    Narrative reviewHair Health forBiotin
  88. The Infatuation With Biotin Supplementation: Is There Truth Behind Its Rising Popularity? A Comparative Analysis of Clinical Efficacy versus Social Popularity.
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    Narrative reviewHair Health forBiotin
  89. Menkes disease and response to copper histidine: An Indian case series.
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  90. Trace element levels in alopecia areata.
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  91. UV damage to hair and the effect of antioxidants and metal chelators.
    Millington KR; Marsh JM · International journal of cosmetic science · 2021
    In vitro / ex vivo studyHair Health forCopper
  92. Preserving fibre health: reducing oxidative stress throughout the life of the hair fibre.
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  94. Beyond Efficacy: 0.6% Selenium Disulfide Shampoo Matches 2% Ketoconazole for Seborrheic Dermatitis with Superior Cosmesis.
    Farris PK; Barbosa V; Houshman EB; Kovylkina N · Journal of drugs in dermatology : JDD · 2026
    Randomized trial87 participantsHair Health forSelenium
  95. Selenium Disulfide-based shampoo applied for 4 weeks significantly improves dandruff and seborrheic dermatitis.
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  96. A Comparative Randomized Clinical Study Assessing the Efficacy of a 1% Selenium Disulfide-Based Shampoo versus 2% Ketoconazole Shampoo in Subjects with Moderate to Severe Scalp Seborrheic Dermatitis.
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  98. Scientific opinion on the tolerable upper intake level for selenium.
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  99. Management of hair loss associated with endocrine therapy in patients with breast cancer: an overview.
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    Narrative reviewHair Health forVitamin C
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    Observational studyHair Health forVitamin C
  102. Removal of synthetic hair dye using formamidine sulfinic acid and other sulfinate precursors.
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    Methods validation studyHair Health forVitamin C
  103. A Zinc Sulphate-Resistant Acrodermatitis Enteropathica Patient with a Novel Mutation in SLC39A4 Gene.
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    Lee S; Kim BJ; Lee CH; Lee WS · Journal of the European Academy of Dermatology and Venereology : JEADV · 2018
    Meta-analysis2,039 participants14 studies pooledHair Health forVitamin D
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    Rashad AF; Elgamal E; Fouda I · Journal of cosmetic dermatology · 2022
    Randomized trial60 participantsHair Health forVitamin D
  106. Vitamin D and its Analogs in Treatment of Mild to Moderate Alopecia Areata: Systematic Review and Meta-Analysis.
    Alsaati AA; Kaliyadan F; Alsaadoun D; Alzakry LM; Alzabadin RA; Hakami TH; Rubaian NFB · Indian dermatology online journal · 2025
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    Randomized trial60 participantsHair Health forVitamin D
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    Meta-analysis10,670 participants23 studies pooledHair Health forVitamin D
  109. The effects of minoxidil, 1% pyrithione zinc and a combination of both on hair density: a randomized controlled trial.
    Berger RS; Fu JL; Smiles KA; Turner CB; Schnell BM; Werchowski KM; Lammers KM · The British journal of dermatology · 2003
    Randomized trial200 participantsHair Health forZinc
  110. Incubatory environment of the scalp impacts pre-emergent hair to affect post-emergent hair cuticle integrity.
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    Randomized trialHair Health forZinc
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    Draelos ZD; Kenneally DC; Hodges LT; Billhimer W; Copas M; Margraf C · The journal of investigative dermatology. Symposium proceedings · 2006
    Randomized trial40 participantsHair Health forZinc
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    Kil MS; Kim CW; Kim SS · Annals of dermatology · 2013
    Case-control study342 participantsHair Health forZinc
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    Goldson AJ; Fairweather-Tait SJ; Armah CN; Bao Y; Broadley MR; Dainty JR; Furniss C; Hart DJ; Teucher B; Hurst R · PloS one · 2011
    Randomized trial119 participantsImmunity forSelenium
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    Janbakhsh A; Mansouri F; Vaziri S; Sayad B; Afsharian M; Rahimi M; Shahebrahimi K; Salari F · Caspian journal of internal medicine · 2013
    Randomized trial62 participantsImmunity forSelenium
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    Yu SY; Li WG; Zhu YJ; Yu WP; Hou C · Biological trace element research · 1990
    Non-randomized trial20,847 participantsImmunity forSelenium
  117. Selenium nanoparticles as adjunctive therapy in sepsis: A pilot randomized clinical trial.
    Gu WJ; Huang W; Zhao FZ; Yuan XK; Jin K; Chen JL; Zhang CY; Huang Y; He L; Zhuang H; Yin HY; Chen T · Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy · 2026
    Randomized trial70 participantsImmunity forSelenium
  118. Selenium supplementation in patients with autoimmune thyroiditis decreases thyroid peroxidase antibodies concentrations.
    Gärtner R; Gasnier BC; Dietrich JW; Krebs B; Angstwurm MW · The Journal of clinical endocrinology and metabolism · 2002
    Randomized trial70 participantsImmunity forSelenium
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    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusImmunity forVitamin C
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    Sun L; Zhao JH; Fan WY; Feng B; Liu WW; Chen RQ; Ban C; Dang AG; Wang M; Luo KT; Zhou GY; Yu FF; Ba Y · Nutrition reviews · 2024
    Meta-analysis2,334 participants14 studies pooledImmunity forVitamin C
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    Abioye AI; Bromage S; Fawzi W · BMJ global health · 2021
    Meta-analysisImmunity forVitamin C
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    Vojdani A; Bazargan M; Vojdani E; Wright J · Cancer detection and prevention · 2001
    Randomized trial20 participantsImmunity forVitamin C
  123. Enhanced Vitamin C Delivery: A Systematic Literature Review Assessing the Efficacy and Safety of Alternative Supplement Forms in Healthy Adults.
    Calder PC; Kreider RB; McKay DL · Nutrients · 2025
    Systematic review13 studies pooledImmunity forVitamin C
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    Martineau AR; Jolliffe DA; Greenberg L; Aloia JF; Bergman P; Dubnov-Raz G; Esposito S; Ganmaa D; Ginde AA; Goodall EC; Grant CC; Janssens W; Jensen ME; Kerley CP; Laaksi I; Manaseki-Holland S; Mauger D; Murdoch DR; Neale R; Rees JR; Simpson S; Stelmach I; Trilok Kumar G; Urashima M; Camargo CA; Griffiths CJ; Hooper RL · Health technology assessment (Winchester, England) · 2020
    Meta-analysis11,321 participants25 studies pooledImmunity forVitamin D
  125. Association Between Vitamin D and Influenza: Meta-Analysis and Systematic Review of Randomized Controlled Trials.
    Zhu Z; Zhu X; Gu L; Zhan Y; Chen L; Li X · Frontiers in nutrition · 2022
    Meta-analysis4,859 participants10 studies pooledImmunity forVitamin D
  126. Vitamin D3 and deconvoluting a rash.
    Ernst MK; Evans ST; Techner JM; Rothbaum RM; Christensen LF; Onay UV; Biyashev D; Demczuk MM; Nguyen CV; Honda KS; McCormick TS; Tsoi LC; Gudjonsson JE; Cooper KD; Lu KQ · JCI insight · 2023
    Randomized trial28 participantsImmunity forVitamin D
  127. Effect of vitamin D3 supplementation on cellular immunity and inflammatory markers in COVID-19 patients admitted to the ICU.
    Bychinin MV; Klypa TV; Mandel IA; Yusubalieva GM; Baklaushev VP; Kolyshkina NA; Troitsky AV · Scientific reports · 2022
    Randomized trial110 participantsImmunity forVitamin D
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    Anitua E; Tierno R; Alkhraisat MH · Clinical nutrition (Edinburgh, Scotland) · 2022
    Meta-analysis50,554 participants65 studies pooledImmunity forVitamin D
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    Vlieg-Boerstra B; de Jong N; Meyer R; Agostoni C; De Cosmi V; Grimshaw K; Milani GP; Muraro A; Oude Elberink H; Pali-Schöll I; Roduit C; Sasaki M; Skypala I; Sokolowska M; van Splunter M; Untersmayr E; Venter C; O'Mahony L; Nwaru BI · Allergy · 2022
    Meta-analysis199,055 participants115 studies pooledImmunity forZinc
  130. Zinc supplementation reduces the incidence of acute lower respiratory infections in infants and preschool children: a double-blind, controlled trial.
    Sazawal S; Black RE; Jalla S; Mazumdar S; Sinha A; Bhan MK · Pediatrics · 1998
    Randomized trial609 participantsImmunity forZinc
  131. A randomized controlled trial of zinc supplementation in the treatment of acute respiratory tract infection in Thai children.
    Rerksuppaphol S; Rerksuppaphol L · Pediatric reports · 2020
    Randomized trial64 participantsImmunity forZinc
  132. The effect of zinc and vitamin A supplementation on immune response in an older population.
    Fortes C; Forastiere F; Agabiti N; Fano V; Pacifici R; Virgili F; Piras G; Guidi L; Bartoloni C; Tricerri A; Zuccaro P; Ebrahim S; Perucci CA · Journal of the American Geriatrics Society · 1998
    Randomized trial136 participantsImmunity forZinc
  133. The role of specific nutrients in preventing immune system and blood cell disorders: an umbrella review.
    Vecchietti A; Strano P; Minutolo G; Grieco V; Cappuccio G; Granvillano G; Confalonieri L; Briganti GL; Raso E; Chimienti M; Pellegrini M; Mercogliano M; Spatari G; Lugli C; Urbano T; Lorenzon A · Journal of preventive medicine and hygiene · 2026
    Systematic review13 studies pooledImmunity forZinc