Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.
- Diagnosis of magnesium-induced diarrhea.
Fine KD; Santa Ana CA; Fordtran JS Ā· The New England journal of medicine Ā· 1991
Clinical trial19 participantsflagDigestive Health forscienceMagnesium
- Profiling inflammatory and oxidative stress biomarkers following taurine supplementation: a systematic review and dose-response meta-analysis of controlled trials.
Faghfouri AH; Seyyed Shoura SM; Fathollahi P; Shadbad MA; Papi S; Ostadrahimi A; Faghfuri E Ā· European journal of clinical nutrition Ā· 2022
Meta-analysisflagStress Relief forscienceTaurine
- L-theanine in the adjunctive treatment of generalized anxiety disorder: A double-blind, randomised, placebo-controlled trial.
Sarris J; Byrne GJ; Cribb L; Oliver G; Murphy J; Macdonald P; Nazareth S; Karamacoska D; Galea S; Short A; Ee C; Birling Y; Menon R; Ng CH Ā· Journal of psychiatric research Ā· 2020
Randomized trial46 participantsflagStress Relief flagSleep Support forscienceTheanine
- Oral intake of γ-aminobutyric acid affects mood and activities of central nervous system during stressed condition induced by mental tasks.
Yoto A; Murao S; Motoki M; Yokoyama Y; Horie N; Takeshima K; Masuda K; Kim M; Yokogoshi H Ā· Amino acids Ā· 2012
Randomized trial63 participantsflagStress Relief flagMood Support forscienceGABA
- Relationship between Whole-Blood Magnesium and Cognitive Performance among Chinese Adults.
Lu Z; He R; Zhang Y; Li B; Li F; Fu Y; Rong S Ā· Nutrients Ā· 2023
Cross-sectional study1,006 participantsflagMental Focus forscienceMagnesium
- Effect of the laxative magnesium oxide on gastrointestinal functional recovery in fast-track colonic resection: a double-blind, placebo-controlled randomized study.
Andersen J; Christensen H; Pachler JH; Hallin M; Thaysen HV; Kehlet H Ā· Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland Ā· 2012
Randomized trial49 participantsflagDigestive Health forscienceMagnesium
- Effect of Combined Ingestion of L-Theanine and L-Arginine for Short-Term Psychological Stress in Young Adults: A Randomized Placebo-Controlled Study.
Furushima D; Sugiyama I; Nomura Y; Unno K; Yamada H Ā· Journal of nutritional science and vitaminology Ā· 2023
Randomized trial120 participantsflagStress Relief forscienceTheanine
- GABA Supplementation, Increased Heart-Rate Variability, Emotional Response, Sleep Efficiency and Reduced Depression in Sedentary Overweight Women Undergoing Physical Exercise: Placebo-Controlled, Randomized Clinical Trial.
Guimarães AP; Seidel H; Pires LVM; Trindade CO; Baleeiro RDS; Souza PM; Silva FGDE; Coelho DB; Becker LK; Oliveira EC · Journal of dietary supplements · 2024
Randomized trial30 participantsflagStress Relief flagSleep Support forscienceGABA
- Protective and therapeutic effectiveness of taurine supplementation plus low calorie diet on metabolic parameters and endothelial markers in patients with diabetes mellitus: a randomized, clinical trial.
Moludi J; Qaisar SA; Kadhim MM; Ahmadi Y; Davari M Ā· Nutrition & metabolism Ā· 2022
Randomized trial120 participantsflagStress Relief forscienceTaurine
- Serum Magnesium and Cognitive Function Among Qatari Adults.
Al-Ghazali K; Eltayeb S; Musleh A; Al-Abdi T; Ganji V; Shi Z Ā· Frontiers in aging neuroscience Ā· 2020
Cross-sectional study1,000 participantsflagMental Focus forscienceMagnesium
- Lactobacillus reuteri DSM 17938 and Magnesium Oxide in Children with Functional Chronic Constipation: A Double-Blind and Randomized Clinical Trial.
Kubota M; Ito K; Tomimoto K; Kanazaki M; Tsukiyama K; Kubota A; Kuroki H; Fujita M; Vandenplas Y Ā· Nutrients Ā· 2020
Randomized trial60 participantsflagDigestive Health forscienceMagnesium
- Anti-Stress, Behavioural and Magnetoencephalography Effects of an L-Theanine-Based Nutrient Drink: A Randomised, Double-Blind, Placebo-Controlled, Crossover Trial.
White DJ; de Klerk S; Woods W; Gondalia S; Noonan C; Scholey AB Ā· Nutrients Ā· 2016
Randomized trial34 participantsflagStress Relief forscienceTheanine
- Magnesium status and attention deficit hyperactivity disorder (ADHD): A meta-analysis.
Effatpanah M; Rezaei M; Effatpanah H; Effatpanah Z; Varkaneh HK; Mousavi SM; Fatahi S; Rinaldi G; Hashemi R Ā· Psychiatry research Ā· 2019
Meta-analysisflagMental Focus forscienceMagnesium
- Taurine supplementation attenuates delayed increase in exercise-induced arterial stiffness.
Ra SG; Choi Y; Akazawa N; Ohmori H; Maeda S Ā· Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme Ā· 2017
Randomized trial29 participantsflagStress Relief forscienceTaurine
- Cortical gamma-aminobutyric acid and glutamate in posttraumatic stress disorder and their relationships to self-reported sleep quality.
Meyerhoff DJ; Mon A; Metzler T; Neylan TC Ā· Sleep Ā· 2014
Case-control study45 participantsflagStress Relief forscienceGABA
- A Randomized Double-blind Placebo-controlled Trial on the Effect of Magnesium Oxide in Patients With Chronic Constipation.
Mori S; Tomita T; Fujimura K; Asano H; Ogawa T; Yamasaki T; Kondo T; Kono T; Tozawa K; Oshima T; Fukui H; Kimura T; Watari J; Miwa H Ā· Journal of neurogastroenterology and motility Ā· 2022
Randomized trial34 participantsflagDigestive Health forscienceMagnesium
- Safety and Efficacy of AlphaWaveĀ® L-Theanine Supplementation for 28 Days in Healthy Adults with Moderate Stress: A Randomized, Double-Blind, Placebo-Controlled Trial.
Moulin M; Crowley DC; Xiong L; Guthrie N; Lewis ED Ā· Neurology and therapy Ā· 2024
Randomized trial30 participantsflagStress Relief flagMental Focus flagProductivity Boost forscienceTheanine
- Comparison of the effects of two amino acids, Gamma-aminobutyric acid (GABA) and L-theanine, on sedation, anxiety, and cognition in preoperative surgical patients - A randomized controlled study.
Deshpande SS; Kurdi M; Baiju A; Athira AS; Sarasamma AG; Gangadharan AK Ā· Journal of anaesthesiology, clinical pharmacology Ā· 2025
Randomized trial168 participantsflagStress Relief flagMood Support forscienceTheanine flagStress Relief forscienceGABA
- The effect of vitamin D and magnesium supplementation on the mental health status of attention-deficit hyperactive children: a randomized controlled trial.
Hemamy M; Pahlavani N; Amanollahi A; Islam SMS; McVicar J; Askari G; Malekahmadi M Ā· BMC pediatrics Ā· 2021
Randomized trial33 participantsflagMental Focus forscienceMagnesium
- Correlations between dietary taurine intake and life stress in Korean college students.
Sung MJ; Chang KJ Ā· Advances in experimental medicine and biology Ā· 2009
Observational studyflagStress Relief forscienceTaurine
- The effect of food, vitamin, or mineral supplements on chronic constipation in adults: A systematic review and meta-analysis of randomized controlled trials.
van der Schoot A; Creedon A; Whelan K; Dimidi E Ā· Neurogastroenterology and motility Ā· 2023
Meta-analysis787 participants8 studies pooledflagDigestive Health forscienceMagnesium
- Effects of L-Theanine Administration on Stress-Related Symptoms and Cognitive Functions in Healthy Adults: A Randomized Controlled Trial.
Hidese S; Ogawa S; Ota M; Ishida I; Yasukawa Z; Ozeki M; Kunugi H Ā· Nutrients Ā· 2020
Randomized trial30 participantsflagStress Relief flagBrain Health flagCognitive Support flagSleep Support forscienceTheanine
- Lactobacillus casei rhamnosus Lcr35 in children with chronic constipation.
Bu LN; Chang MH; Ni YH; Chen HL; Cheng CC Ā· Pediatrics international : official journal of the Japan Pediatric Society Ā· 2007
Randomized trial45 participantsflagDigestive Health forscienceMagnesium
- Effects of L-theanine or caffeine intake on changes in blood pressure under physical and psychological stresses.
Yoto A; Motoki M; Murao S; Yokogoshi H Ā· Journal of physiological anthropology Ā· 2013
Randomized trial14 participantsflagStress Relief forscienceTheanine
- Efficacy of oral magnesium therapy in the treatment of chronic constipation in spastic cerebral palsy children: a randomized controlled trial.
Hassanein SMA; Deifallah SM; Bastawy HA Ā· World journal of pediatrics : WJP Ā· 2021
Randomized trial100 participantsflagDigestive Health forscienceMagnesium
- A Randomized, Triple-Blind, Placebo-Controlled, Crossover Study to Investigate the Efficacy of a Single Dose of AlphaWaveĀ® L-Theanine on Stress in a Healthy Adult Population.
Evans M; McDonald AC; Xiong L; Crowley DC; Guthrie N Ā· Neurology and therapy Ā· 2021
Randomized trialflagStress Relief flagBrain Health forscienceTheanine
- Ca:Mg ratio, medium-chain fatty acids, and the gut microbiome.
Fan L; Zhu X; Sun S; Yu C; Huang X; Ness R; Dugan LL; Shu L; Seidner DL; Murff HJ; Fodor AA; Azcarate-Peril MA; Shrubsole MJ; Dai Q Ā· Clinical nutrition (Edinburgh, Scotland) Ā· 2022
Randomized trial240 participantsflagDigestive Health forscienceMagnesium
- The Magnesium-Rich Formula for Functional Constipation in Infants: a Randomized Comparator-Controlled Study.
Benninga MA; MENA Infant Constipation Study Group; Vandenplas Y Ā· Pediatric gastroenterology, hepatology & nutrition Ā· 2022
Randomized trial286 participantsflagDigestive Health forscienceMagnesium
- The Effects of Green Tea Amino Acid L-Theanine Consumption on the Ability to Manage Stress and Anxiety Levels: a Systematic Review.
Williams JL; Everett JM; D'Cunha NM; Sergi D; Georgousopoulou EN; Keegan RJ; McKune AJ; Mellor DD; Anstice N; Naumovski N Ā· Plant foods for human nutrition (Dordrecht, Netherlands) Ā· 2020
Systematic review9 studies pooledflagStress Relief flagMood Support forscienceTheanine
- Magnesium-Rich Mineral Water Improves Stool Consistency and Bowel Habits in Healthy Subjects: A Randomized Controlled Trial.
Yoneda H; Tomita T; Kitano T; Morishita D; Kodani M; Nishii N; Sei H; Eda H; Sato T; Kawai M; Yokoyama Y; Igeta M; Okugawa T; Fukui H; Shinzaki S Ā· Neurogastroenterology and motility Ā· 2026
Randomized trial40 participantsflagDigestive Health forscienceMagnesium
- L-theanine relieves positive, activation, and anxiety symptoms in patients with schizophrenia and schizoaffective disorder: an 8-week, randomized, double-blind, placebo-controlled, 2-center study.
Ritsner MS; Miodownik C; Ratner Y; Shleifer T; Mar M; Pintov L; Lerner V Ā· The Journal of clinical psychiatry Ā· 2011
Randomized trial60 participantsflagStress Relief flagMood Support forscienceTheanine
- Association between Serum Magnesium and Fractures: A Systematic Review and Meta-Analysis of Observational Studies.
Dominguez LJ; Veronese N; Ciriminna S; Pérez-Albela JL; VÔsquez-López VF; Rodas-Regalado S; Di Bella G; Parisi A; Tagliaferri F; Barbagallo M · Nutrients · 2023
Meta-analysis119,755 participants4 studies pooledflagBone Health forscienceMagnesium
- Bioabsorbable Magnesium-Based Materials Potential and Safety in Bone Surgery: A Systematic Review.
Hung CH; Kwok YC; Yip J; Wong HH; Leung YY Ā· Craniomaxillofacial trauma & reconstruction Ā· 2025
Systematic review386 participants8 studies pooledflagBone Health forscienceMagnesium
- Vascularized bone grafting fixed by biodegradable magnesium screw for treating osteonecrosis of the femoral head.
Zhao D; Huang S; Lu F; Wang B; Yang L; Qin L; Yang K; Li Y; Li W; Wang W; Tian S; Zhang X; Gao W; Wang Z; Zhang Y; Xie X; Wang J; Li J Ā· Biomaterials Ā· 2016
Randomized trial48 participantsflagBone Health forscienceMagnesium
- An update on magnesium and bone health.
Rondanelli M; Faliva MA; Tartara A; Gasparri C; Perna S; Infantino V; Riva A; Petrangolini G; Peroni G Ā· Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine Ā· 2022
Narrative reviewflagBone Health forscienceMagnesium
- Sex-specific differences in the association of magnesium intake with femoral neck bone mineral density among older adults.
Wang B; Tan X; Yao X; Zhu Z Ā· Endocrine connections Ā· 2025
Cross-sectional study1,343 participantsflagBone Health forscienceMagnesium
- Antenatal magnesium sulfate and neuroprotection.
Doyle LW Ā· Current opinion in pediatrics Ā· 2012
Meta-analysis6,145 participants5 studies pooledflagBrain Health forscienceMagnesium
- No. 376-Magnesium Sulphate for Fetal Neuroprotection.
Magee LA; De Silva DA; Sawchuck D; Synnes A; von Dadelszen P Ā· Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC Ā· 2020
Guideline / consensus4,446 participantsflagBrain Health forscienceMagnesium
- Magnesium Sulfate Before Preterm Birth for Neuroprotection: An Updated Cochrane Systematic Review.
Shepherd ES; Goldsmith S; Doyle LW; Middleton P; Marret S; Rouse DJ; Pryde P; Wolf HT; Crowther CA Ā· Obstetrics and gynecology Ā· 2024
Systematic review5,917 participants6 studies pooledflagBrain Health forscienceMagnesium
- Magnesium sulphate for fetal neuroprotection at imminent risk for preterm delivery: a systematic review with meta-analysis and trial sequential analysis.
Wolf HT; Huusom LD; Henriksen TB; Hegaard HK; Brok J; Pinborg A Ā· BJOG : an international journal of obstetrics and gynaecology Ā· 2020
Meta-analysis5,917 participants6 studies pooledflagBrain Health forscienceMagnesium
- Magnesium sulfate and fetal neuroprotection: overview of clinical evidence.
Chollat C; Marret S Ā· Neural regeneration research Ā· 2020
Narrative reviewflagBrain Health forscienceMagnesium
- Effects of Tea (Camellia sinensis) or its Bioactive Compounds l-Theanine or l-Theanine plus Caffeine on Cognition, Sleep, and Mood in Healthy Participants: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
Payne ER; Aceves-Martins M; Dubost J; Greyling A; de Roos B Ā· Nutrition reviews Ā· 2025
Meta-analysis50 studies pooledflagBrain Health flagCognitive Support flagMental Focus forscienceTheanine
- Assessing the effects of caffeine and theanine on the maintenance of vigilance during a sustained attention task.
Foxe JJ; Morie KP; Laud PJ; Rowson MJ; de Bruin EA; Kelly SP Ā· Neuropharmacology Ā· 2012
Randomized trial27 participantsflagBrain Health flagCognitive Support forscienceTheanine
- Effects of l-Theanine on Cognitive Function in Middle-Aged and Older Subjects: A Randomized Placebo-Controlled Study.
Baba Y; Inagaki S; Nakagawa S; Kaneko T; Kobayashi M; Takihara T Ā· Journal of medicinal food Ā· 2021
Randomized trialflagBrain Health flagMental Focus flagProductivity Boost forscienceTheanine
- Circulating and dietary magnesium and risk of cardiovascular disease: a systematic review and meta-analysis of prospective studies.
Del Gobbo LC; Imamura F; Wu JH; de Oliveira Otto MC; Chiuve SE; Mozaffarian D Ā· The American journal of clinical nutrition Ā· 2013
Meta-analysis313,041 participants16 studies pooledflagCardiovascular Support forscienceMagnesium
- Magnesium and the risk of cardiovascular events: a meta-analysis of prospective cohort studies.
Qu X; Jin F; Hao Y; Li H; Tang T; Wang H; Yan W; Dai K Ā· PloS one Ā· 2013
Meta-analysis532,979 participants19 studies pooledflagCardiovascular Support forscienceMagnesium
- Quantitative Association Between Serum/Dietary Magnesium and Cardiovascular Disease/Coronary Heart Disease Risk: A Dose-Response Meta-analysis of Prospective Cohort Studies.
Zhao L; Hu M; Yang L; Xu H; Song W; Qian Y; Zhao M Ā· Journal of cardiovascular pharmacology Ā· 2020
Meta-analysis544,581 participants18 studies pooledflagCardiovascular Support flagHeart Health forscienceMagnesium
- Comparative Efficacy of Nutraceuticals on Endothelial Function: A Systematic Review and Network Meta-Analysis.
Norouzzadeh M; Rashedi MH; Mahdavi-Mazdeh G; Kosari A; Shahinfar H Ā· Current atherosclerosis reports Ā· 2026
Meta-analysisflagCardiovascular Support flagHeart Health forscienceMagnesium
- Serum magnesium, mortality, and cardiovascular disease in chronic kidney disease and end-stage renal disease patients: a systematic review and meta-analysis.
Xiong J; He T; Wang M; Nie L; Zhang Y; Wang Y; Huang Y; Feng B; Zhang J; Zhao J Ā· Journal of nephrology Ā· 2020
Meta-analysis200,934 participants20 studies pooledflagCardiovascular Support forscienceMagnesium
- Taurine Supplementation Lowers Blood Pressure and Improves Vascular Function in Prehypertension: Randomized, Double-Blind, Placebo-Controlled Study.
Sun Q; Wang B; Li Y; Sun F; Li P; Xia W; Zhou X; Li Q; Wang X; Chen J; Zeng X; Zhao Z; He H; Liu D; Zhu Z Ā· Hypertension (Dallas, Tex. : 1979) Ā· 2016
Randomized trial120 participantsflagCardiovascular Support flagHeart Health forscienceTaurine
- Taurine ameliorates blood pressure and vascular function in patients with type 2 diabetes: Randomized, double-blind, placebo-controlled trial.
Li Y; Wang Q; Liu Y; Li Q; Xia W; Lin S; Yang Q; Scholze A; Zhao Z; He H; Zhang H; Yan Z; Tepel M; Mu H; Zhu Z; Liu D Ā· iScience Ā· 2025
Randomized trial165 participantsflagCardiovascular Support flagHeart Health forscienceTaurine
- Taurine reduces the risk for metabolic syndrome: a systematic review and meta-analysis of randomized controlled trials.
Tzang CC; Chi LY; Lin LH; Lin TY; Chang KV; Wu WT; ĆzƧakar L Ā· Nutrition & diabetes Ā· 2024
Meta-analysis1,024 participants25 studies pooledflagCardiovascular Support forscienceTaurine
- Effects of Oral Taurine Supplementation on Cardiometabolic Risk Factors: A Meta-analysis and Systematic Review of Randomized Clinical Trials.
Nie Z; Liu Y; Zhang M; Wu C; Cao Q; Xu J; Zheng Y; Min Z; Zhang W; Han S Ā· Nutrition reviews Ā· 2025
Meta-analysis34 studies pooledflagCardiovascular Support flagGeneral Health forscienceTaurine
- The effects of taurine supplementation on glycemic control and serum lipid profile in patients with type 2 diabetes: a randomized, double-blind, placebo-controlled trial.
Maleki V; Alizadeh M; Esmaeili F; Mahdavi R Ā· Amino acids Ā· 2021
Randomized trial45 participantsflagCardiovascular Support forscienceTaurine
- Magnesium sulphate for women at risk of preterm birth for neuroprotection of the fetus.
Doyle LW; Crowther CA; Middleton P; Marret S; Rouse D Ā· The Cochrane database of systematic reviews Ā· 2009
Meta-analysis6,145 participants5 studies pooledflagCognitive Support forscienceMagnesium
- Effects of magnesium valproate adjuvant therapy on patients with dementia: A systematic review and meta-analysis.
Zhang C; Sun L; Sun H Ā· Medicine Ā· 2022
Meta-analysis1,899 participants22 studies pooledflagCognitive Support forscienceMagnesium
- Effects of magnesium supplementation on serum brain-derived neurotrophic factor levels and cognitive function in patients undergoing fluoxetine therapy for depression.
Noor NJ; Syamsuddin S; Liaury K; Tawali S; Idris I; Azis I; Lisal ST Ā· East Asian archives of psychiatry : official journal of the Hong Kong College of Psychiatrists = Dong Ya jing shen ke xue zhi : Xianggang jing shen ke yi xue yuan qi kan Ā· 2026
Randomized trial40 participantsflagCognitive Support forscienceMagnesium
- Magnesium-L-threonate improves sleep quality and daytime functioning in adults with self-reported sleep problems: A randomized controlled trial.
Hausenblas HA; Lynch T; Hooper S; Shrestha A; Rosendale D; Gu J Ā· Sleep medicine: X Ā· 2025
Randomized trial80 participantsflagCognitive Support flagEnergy forscienceMagnesium
- Could intraoperative magnesium sulphate protect against postoperative cognitive dysfunction?
Hassan WF; Tawfik MH; Nabil TM; Abd Elkareem RM Ā· Minerva anestesiologica Ā· 2021
Randomized trial80 participantsflagCognitive Support forscienceMagnesium
- Dose-response effect of L-theanine on psychomotor speed, sustained attention, and inhibitory control: a double-blind, placebo-controlled, crossover study.
Dassanayake TL; Wijesundara D; Kahathuduwa CN; Weerasinghe VS Ā· Nutritional neuroscience Ā· 2023
Randomized trial32 participantsflagCognitive Support forscienceTheanine
- Acute effects of theanine, caffeine and theanine-caffeine combination on attention.
Kahathuduwa CN; Dassanayake TL; Amarakoon AMT; Weerasinghe VS Ā· Nutritional neuroscience Ā· 2018
Clinical trial20 participantsflagCognitive Support flagMental Focus forscienceTheanine
- Total magnesium intake and risk of frailty in older women.
Struijk EA; Fung TT; Bischoff-Ferrari HA; Willett WC; Lopez-Garcia E Ā· Journal of cachexia, sarcopenia and muscle Ā· 2024
Cohort study81,524 participantsflagEnergy forscienceMagnesium
- Red blood cell magnesium and chronic fatigue syndrome.
Cox IM; Campbell MJ; Dowson D Ā· Lancet (London, England) Ā· 1991
Randomized trial32 participantsflagEnergy forscienceMagnesium
- Exercise, magnesium and immune function.
Laires MJ; Monteiro C Ā· Magnesium research Ā· 2008
Narrative reviewflagEnergy forscienceMagnesium
- Perioperative systemic magnesium to minimize postoperative pain: a meta-analysis of randomized controlled trials.
De Oliveira GS; Castro-Alves LJ; Khan JH; McCarthy RJ Ā· Anesthesiology Ā· 2013
Meta-analysis1,257 participants20 studies pooledflagGeneral Health forscienceMagnesium
- Long-term outcome after intravenous magnesium sulphate in suspected acute myocardial infarction: the second Leicester Intravenous Magnesium Intervention Trial (LIMIT-2).
Woods KL; Fletcher S Ā· Lancet (London, England) Ā· 1994
Randomized trial2,316 participantsflagGeneral Health forscienceMagnesium
- Association of magnesium sulfate use with mortality in critically ill patients with sepsis: a retrospective propensity score-matched cohort study.
Gu WJ; Duan XJ; Liu XZ; Cen Y; Tao LY; Lyu J; Yin HY Ā· British journal of anaesthesia Ā· 2023
Cohort study10,999 participantsflagGeneral Health forscienceMagnesium
- Hypomagnesemia and Mortality in Incident Hemodialysis Patients.
Li L; Streja E; Rhee CM; Mehrotra R; Soohoo M; Brunelli SM; Kovesdy CP; Kalantar-Zadeh K Ā· American journal of kidney diseases : the official journal of the National Kidney Foundation Ā· 2016
Cohort study9,359 participantsflagGeneral Health forscienceMagnesium
- The effects of magnesium supplementation on abnormal uterine bleeding, alopecia, quality of life, and acne in women with polycystic ovary syndrome: a randomized clinical trial.
Jaripur M; Ghasemi-Tehrani H; Askari G; Gholizadeh-Moghaddam M; Clark CCT; Rouhani MH Ā· Reproductive biology and endocrinology : RB&E Ā· 2022
Randomized trial64 participantsflagGeneral Health forscienceMagnesium
- Cognitive Effects of Taurine and Related Sulphur-Containing Amino Acids: A Systematic Review of Human Trials and Considerations for Plant-Based Dietary Transitions.
Moore JA; Cousins AL; Taylor RMJ; Griffiths AR; Young HA Ā· Foods (Basel, Switzerland) Ā· 2026
Systematic review244 participants8 studies pooledflagGeneral Health forscienceTaurine
- Association between habitual dietary taurine intake and the risk of metabolic dysfunction-associated steatotic liver disease: a prospective cohort study.
Zhang S; Xu X; Wang D; Gu Y; Wu H; Meng G; Zhang Q; Liu L; Borné Y; Niu K; Bai L · Food & function · 2026
Cohort study16,699 participantsflagGeneral Health forscienceTaurine
- Effects of magnesium supplementation on improving hyperglycemia, hypercholesterolemia, and hypertension in type 2 diabetes: A pooled analysis of 24 randomized controlled trials.
Xu L; Li X; Wang X; Xu M Ā· Frontiers in nutrition Ā· 2023
Meta-analysis1,325 participants24 studies pooledflagHeart Health forscienceMagnesium
- The effect of lowering blood pressure by magnesium supplementation in diabetic hypertensive adults with low serum magnesium levels: a randomized, double-blind, placebo-controlled clinical trial.
Guerrero-Romero F; RodrĆguez-MorĆ”n M Ā· Journal of human hypertension Ā· 2009
Randomized trial82 participantsflagHeart Health forscienceMagnesium
- Positive effects of magnesium supplementation in metabolic syndrome.
Kisters S; Kisters K; Werner T; Vormann J; Tokmak F; Westhoff T; Gröber U; Predel HG; Reuter H · International journal of clinical pharmacology and therapeutics · 2024
Randomized trial54 participantsflagHeart Health forscienceMagnesium
- Seafood diets: hypolipidemic and antiatherogenic effects of taurine and n-3 fatty acids.
Elvevoll EO; Eilertsen KE; Brox J; Dragnes BT; Falkenberg P; Olsen JO; Kirkhus B; Lamglait A; Ćsterud B Ā· Atherosclerosis Ā· 2009
Randomized trial80 participantsflagHeart Health forscienceTaurine
- The effects of taurine supplementation on obesity, blood pressure and lipid profile: A meta-analysis of randomized controlled trials.
Guan L; Miao P Ā· European journal of pharmacology Ā· 2021
Meta-analysis12 studies pooledflagHeart Health forscienceTaurine
- The Effects of Oral Taurine on Resting Blood Pressure in Humans: a Meta-Analysis.
Waldron M; Patterson SD; Tallent J; Jeffries O Ā· Current hypertension reports Ā· 2019
Meta-analysis103 participants7 studies pooledflagHeart Health forscienceTaurine
- The effects of magnesium L-threonate (MagteinĀ®) on cognitive performance and sleep quality in adults: a randomised, double-blind, placebo-controlled trial.
Lopresti AL; Smith SJ Ā· Frontiers in nutrition Ā· 2026
Randomized trial100 participantsflagMental Focus flagProductivity Boost forscienceMagnesium
- Effect of L-theanine on selective attention in a traffic-related reaction task in sleep-deprived young adults: a double-blind placebo-controlled, crossover study.
Karunaratne UW; Dassanayake TL Ā· Nutritional neuroscience Ā· 2025
Randomized trial24 participantsflagMental Focus forscienceTheanine
- Peripartum neuroactive steroid and γ-aminobutyric acid profiles in women at-risk for postpartum depression.
Deligiannidis KM; Kroll-Desrosiers AR; Mo S; Nguyen HP; Svenson A; Jaitly N; Hall JE; Barton BA; Rothschild AJ; Shaffer SA Ā· Psychoneuroendocrinology Ā· 2017
Cohort study56 participantsflagMood Support forscienceGABA
- The role of neurotransmitters in mediating the relationship between brain alterations and depressive symptoms in patients with inflammatory bowel disease.
Wang J; Liu G; Xu K; Ai K; Huang W; Zhang J Ā· Human brain mapping Ā· 2023
Case-control study69 participantsflagMood Support forscienceGABA
- Occipital gamma-aminobutyric acid and glutamate-glutamine alterations in major depressive disorder: An mrs study and meta-analysis.
Truong V; Cheng PZ; Lee HC; Lane TJ; Hsu TY; Duncan NW Ā· Psychiatry research. Neuroimaging Ā· 2021
Observational studyflagMood Support forscienceGABA
- Systematic review of gamma-aminobutyric-acid inhibitory deficits across the reproductive life cycle.
Vigod SN; Strasburg K; Daskalakis ZJ; Blumberger DM Ā· Archives of women's mental health Ā· 2014
Systematic review11 studies pooledflagMood Support forscienceGABA
- Protective role of antioxidant supplementation for depression and anxiety: A meta-analysis of randomized clinical trials.
Wang H; Jin M; Xie M; Yang Y; Xue F; Li W; Zhang M; Li Z; Li X; Jia N; Liu Y; Cui X; Hu G; Dong L; Wang G; Yu Q Ā· Journal of affective disorders Ā· 2023
Meta-analysis4,049 participants52 studies pooledflagMood Support forscienceMagnesium
- Role of magnesium supplementation in the treatment of depression: A randomized clinical trial.
Tarleton EK; Littenberg B; MacLean CD; Kennedy AG; Daley C Ā· PloS one Ā· 2017
Randomized trial126 participantsflagMood Support flagStress Relief forscienceMagnesium
- Magnesium supplementation as an adjunct to fluoxetine therapy for depression.
Walyddaini AS; Lisal ST; Ilhamuddin; Zainuddin AA; Tanra AJ; Widianingsih Y; Syamsuddin S Ā· East Asian archives of psychiatry : official journal of the Hong Kong College of Psychiatrists = Dong Ya jing shen ke xue zhi : Xianggang jing shen ke yi xue yuan qi kan Ā· 2026
Randomized trial40 participantsflagMood Support forscienceMagnesium
- The effects of magnesium supplementation on serum level of brain derived neurotrophic factor (BDNF) and depression status in patients with depression.
Afsharfar M; Shahraki M; Shakiba M; Asbaghi O; Dashipour A Ā· Clinical nutrition ESPEN Ā· 2021
Randomized trial46 participantsflagMood Support forscienceMagnesium
- Dietary magnesium intake and risk of depression.
Sun C; Wang R; Li Z; Zhang D Ā· Journal of affective disorders Ā· 2019
Cross-sectional study17,730 participantsflagMood Support forscienceMagnesium
- l-theanine adjunct to sertraline for major depressive disorder: A randomized, double-blind, placebo-controlled clinical trial.
Shamabadi A; Kafi F; Arab Bafrani M; Asadigandomani H; A Basti F; Akhondzadeh S Ā· Journal of affective disorders Ā· 2023
Randomized trial60 participantsflagMood Support forscienceTheanine
- Anti-stress effect of theanine on students during pharmacy practice: positive correlation among salivary α-amylase activity, trait anxiety and subjective stress.
Unno K; Tanida N; Ishii N; Yamamoto H; Iguchi K; Hoshino M; Takeda A; Ozawa H; Ohkubo T; Juneja LR; Yamada H Ā· Pharmacology, biochemistry, and behavior Ā· 2014
Randomized trial20 participantsflagMood Support forscienceTheanine
- Cross-sectional and longitudinal associations of magnesium intake and cognition in the Healthy Aging Longitudinal Study in Taiwan.
Tao MH; Chuang SC; Wu IC; Chan HT; Cheng CW; Chen HL; Lee MM; Chang HY; Hsiung CA; Hsu CC Ā· European journal of nutrition Ā· 2024
Cohort study5,663 participantsflagProductivity Boost forscienceMagnesium
- Low levels of serum magnesium are associated with poststroke cognitive impairment in ischemic stroke patients.
Tu X; Qiu H; Lin S; He W; Huang G; Zhang X; Wu Y; He J Ā· Neuropsychiatric disease and treatment Ā· 2022
Cohort study327 participantsflagProductivity Boost forscienceMagnesium
- Hypomagnesemia and Acute Cognitive Decline in Older Adults: An Evaluation of Clinical Practice and Cognitive Outcomes at a National Health Service (NHS) Trust in England.
Lai XN; Sadhwani V; Ng WM; Gani A Ā· Cureus Ā· 2025
Cohort study667 participantsflagProductivity Boost forscienceMagnesium
- Magnesium Depletion Score as a Novel Predictor of Cognitive Impairment: A Population-Based Cross-Sectional Study From NHANES.
Chen M; Xue R; Zhang M; Zhang J; Zheng J; Ye D; Sun J Ā· Journal of the American Medical Directors Association Ā· 2025
Cross-sectional study2,768 participantsflagProductivity Boost forscienceMagnesium
- Cognitive and affective effects of L-Theanine: a systematic review and meta-analysis of 31 randomized trials.
Gerolymos C; Saddier E; Boyer L; Fond G Ā· Molecular psychiatry Ā· 2026
Meta-analysis1,168 participants31 studies pooledflagProductivity Boost forscienceTheanine
- Effects of L-theanine on cognition, mood and sleep: evidence from human trials.
Cotter J; Kilpatrick HE Ā· Frontiers in nutrition Ā· 2026
Narrative reviewflagProductivity Boost forscienceTheanine
- Time for tea: mood, blood pressure and cognitive performance effects of caffeine and theanine administered alone and together.
Rogers PJ; Smith JE; Heatherley SV; Pleydell-Pearce CW Ā· Psychopharmacology Ā· 2008
Randomized trial48 participantsflagProductivity Boost forscienceTheanine
- Safety and Efficacy of Gamma-Aminobutyric Acid from Fermented Rice Germ in Patients with Insomnia Symptoms: A Randomized, Double-Blind Trial.
Byun JI; Shin YY; Chung SE; Shin WC Ā· Journal of clinical neurology (Seoul, Korea) Ā· 2020
Randomized trial40 participantsflagSleep Support forscienceGABA
- Analysis of the Effects of Known Sleep-Support Supplements in Relation to Life Habits, Sleep Conditions, and Sleep Problems.
Imafuku F; Yamamoto K; Tanaka E; Aoki R; Nishino S Ā· Nutrients Ā· 2023
Randomized trial160 participantsflagSleep Support forscienceGABA
- Reduced γ-aminobutyric acid in occipital and anterior cingulate cortices in primary insomnia: a link to major depressive disorder?
Plante DT; Jensen JE; Schoerning L; Winkelman JW Ā· Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology Ā· 2012
Case-control study40 participantsflagSleep Support forscienceGABA
- Effects of magnesium and potassium supplementation on insomnia and sleep hormones in patients with diabetes mellitus.
Khalid S; Bashir S; Mehboob R; Anwar T; Ali M; Hashim M; Waseem H; Basharat S Ā· Frontiers in endocrinology Ā· 2024
Randomized trial320 participantsflagSleep Support forscienceMagnesium
- Association of magnesium intake with sleep duration and sleep quality: findings from the CARDIA study.
Zhang Y; Chen C; Lu L; Knutson KL; Carnethon MR; Fly AD; Luo J; Haas DM; Shikany JM; Kahe K Ā· Sleep Ā· 2022
Cohort study3,964 participantsflagSleep Support forscienceMagnesium
- Lidocaine vs. magnesium: effect on analgesia after a laparoscopic cholecystectomy.
Saadawy IM; Kaki AM; Abd El Latif AA; Abd-Elmaksoud AM; Tolba OM Ā· Acta anaesthesiologica Scandinavica Ā· 2010
Randomized trial120 participantsflagSleep Support forscienceMagnesium
- The effect of magnesium supplementation on primary insomnia in elderly: A double-blind placebo-controlled clinical trial.
Abbasi B; Kimiagar M; Sadeghniiat K; Shirazi MM; Hedayati M; Rashidkhani B Ā· Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences Ā· 2013
Randomized trial46 participantsflagSleep Support forscienceMagnesium
- A randomized, double-blind, placebo-controlled, multicenter study assessing the efficacy of magnesium oxide monohydrate in the treatment of nocturnal leg cramps.
Barna O; Lohoida P; Holovchenko Y; Bazylevych A; Velychko V; Hovbakh I; Bula L; Shechter M Ā· Nutrition journal Ā· 2021
Randomized trial175 participantsflagSleep Support forscienceMagnesium
- Comparison Between Efficacy of Oral Melatonin and Oral L-theanine in Improving Sleep in Cancer Patients Suffering From Insomnia: A Randomised Double-blinded Placebo-controlled Study.
Kurdi MS; As A; Ladhad DA; Mitragotri MV; Baiju A Ā· Indian journal of palliative care Ā· 2024
Randomized trial120 participantsflagSleep Support forscienceTheanine
- The effects of L-theanine consumption on sleep outcomes: A systematic review and meta-analysis.
Bulman A; D'Cunha NM; Marx W; Turner M; McKune A; Naumovski N Ā· Sleep medicine reviews Ā· 2025
Meta-analysis897 participants19 studies pooledflagSleep Support forscienceTheanine
- In Search of a Safe Natural Sleep Aid.
Rao TP; Ozeki M; Juneja LR Ā· Journal of the American College of Nutrition Ā· 2016
Narrative reviewflagSleep Support forscienceTheanine
- Relieving occupational fatigue by consumption of a beverage containing γ-amino butyric acid.
Kanehira T; Nakamura Y; Nakamura K; Horie K; Horie N; Furugori K; Sauchi Y; Yokogoshi H Ā· Journal of nutritional science and vitaminology Ā· 2011
Clinical trial30 participantsflagStress Relief forscienceGABA
- Effects of Intravenous Esketamine or Magnesium Sulfate on Early Postoperative Negative Emotions and Pain in Patients Undergoing Endoscopic Sinus Surgery: A Randomized Controlled Trial.
Wang L; Zhou J; Liu Q; Qian K; Wang L; Xie C Ā· Therapeutics and clinical risk management Ā· 2026
Randomized trial137 participantsflagStress Relief forscienceMagnesium
- Effect of short-term magnesium supplementation on anxiety, depression and sleep quality in patients after open-heart surgery.
Saba S; Faizi F; Sepandi M; Nehrir B Ā· Magnesium research Ā· 2022
Non-randomized trial60 participantsflagStress Relief forscienceMagnesium
- Effects of dry needling compared to magnesium infiltration in trigger points for patients with myofascial pain syndrome: a randomized controlled study in Tunisia.
Dhouibi J; Moncer R; Kalbousi N; Gaddour M; Laayouni S; Ouanes W; Kacem B; Jemni S Ā· Korean journal of family medicine Ā· 2026
Randomized trial45 participantsflagStress Relief forscienceMagnesium
- Effect of magnesium and vitamin B6 supplementation on mental health and quality of life in stressed healthy adults: Post-hoc analysis of a randomised controlled trial.
Noah L; Dye L; Bois De Fer B; Mazur A; Pickering G; Pouteau E Ā· Stress and health : journal of the International Society for the Investigation of Stress Ā· 2021
Randomized trialflagStress Relief forscienceMagnesium
- Effects of taurine supplementation on VDT work induced visual stress.
Zhang M; Bi LF; Ai YD; Yang LP; Wang HB; Liu ZY; Sekine M; Kagamimori S Ā· Amino acids Ā· 2005
Randomized trial25 participantsflagStress Relief forscienceTaurine
- Magnesium and anabolic hormones in older men.
Maggio M; Ceda GP; Lauretani F; Cattabiani C; Avantaggiato E; Morganti S; Ablondi F; Bandinelli S; Dominguez LJ; Barbagallo M; Paolisso G; Semba RD; Ferrucci L Ā· International journal of andrology Ā· 2012
Cohort study399 participantsflagTestosterone Support forscienceMagnesium
- Analysis of the relationship between the blood concentration of several metals, macro- and micronutrients and endocrine disorders associated with male aging.
Rotter I; Kosik-Bogacka DI; DoÅÄgowska B; Safranow K; KuczyÅska M; LaszczyÅska M Ā· Environmental geochemistry and health Ā· 2017
Cross-sectional study313 participantsflagTestosterone Support forscienceMagnesium
- Effect of magnesium supplementation in improving hyperandrogenism, hirsutism, and sleep quality in women with polycystic ovary syndrome: A randomized, placebo-controlled clinical trial.
Gholizadeh-Moghaddam M; Ghasemi-Tehrani H; Askari G; Jaripur M; Clark CCT; Rouhani MH Ā· Health science reports Ā· 2024
Randomized trial64 participantsflagTestosterone Support forscienceMagnesium
- The effects of trace element supplementation on glycolipid metabolism in PCOS: a systematic review and meta-analysis.
Yang L; Gao Y; Zhao W; Qi Y; Duo X; Wang H Ā· Frontiers in nutrition Ā· 2025
Meta-analysis1,600 participants25 studies pooledflagTestosterone Support forscienceMagnesium
- Effects of magnesium supplementation on testosterone levels of athletes and sedentary subjects at rest and after exhaustion.
Cinar V; Polat Y; Baltaci AK; Mogulkoc R Ā· Biological trace element research Ā· 2011
Non-randomized trial20 participantsflagTestosterone Support forscienceMagnesium