Product Image

Magnesium 250 mg

21st Century
4.7
★ ★ ★ ★ ★
(73058 ratings)
Magnesium 250 mg
Product Image
Score79
A very inexpensive oxide tablet offers a useful label amount but limited absorption. The small calcium addition does not address the main form-quality weakness.
How scoring works
Quantity:110 Tablet(s) • (110 servings)
Goals:
Energy
Heart Health
General Health
Stress Relief

Score 79

A very inexpensive oxide tablet offers a useful label amount but limited absorption. The small calcium addition does not address the main form-quality weakness.
How scoring works
$4.99($0.04 per serving)
iHerb
$ 4.99
Report prices

Analysis

The tablet supplies 250 mg of magnesium oxide plus 65 mg of calcium carbonate. The magnesium amount is meaningful on the label, yet oxide provides weaker systemic absorption than citrate or chelated forms.

The simple formula may support occasional bowel motility and can contribute some magnesium when dietary intake is low. It is less suited to users seeking predictable support for muscles, stress, bone, or cardiovascular function.

Low cost and a one-tablet serving are clear practical advantages. Better-absorbed magnesium forms would provide stronger quality even if their label amount were lower.

Who is it for
  • Budget-focused adults who tolerate magnesium oxide
  • People seeking a simple mineral tablet with possible motility effects
Best for
  • Low-cost basic supplementation
  • Occasional stool-softening support

Pros

  • Meaningful 250 mg magnesium amount
  • Very simple formula
  • Convenient one-tablet serving

Cons

  • Oxide has poor systemic absorption
  • Calcium carbonate adds little to the main purpose
  • Weak choice for high-confidence replenishment

Warnings

  • Magnesium oxide may cause diarrhea, cramping, or urgency despite limited systemic absorption.
  • Magnesium can bind tetracycline or quinolone antibiotics and oral bisphosphonates, so these medicines should be taken several hours apart.
  • Impaired kidney function can reduce magnesium clearance, making a large supplemental amount less appropriate without clinical guidance.

Nutrient quality

73 High impact

Magnesium oxide has poor systemic absorption, and calcium carbonate is also a basic form. The magnesium amount is useful on paper, while the small calcium amount adds little.

Ingredient transparency

87 Highest impact

Both magnesium and calcium amounts are clearly stated. Magnesium oxide and calcium carbonate are named precisely.

Customer satisfaction

73 High impact

The aggregate rating is strong and the available feedback volume gives it useful support. No specific review comments are supplied to assess recurring benefits or complaints.

Value for money

79 High impact

Exceptional affordability is the main strength, while weak absorption limits quality value. The small calcium addition contributes only modest practical benefit.

Report analysis

Goals

Energy
Energy
Impact
High effect
B+ Goal FitC+ Strength of SupportF CoverageA Formula Quality
Magnesium · 250 mg

Magnesium directly participates in ATP production and reaches the target amount for energy support. A single mineral supplies useful depth but does not address alertness or stress resilience.

The elemental amount is fully disclosed and falls in a practical daily range. Magnesium oxide has poor systemic absorption, sharply reducing quality-adjusted dose confidence.

Study evidence
Magnesium Supportive 4 studies
Heart Health
Healthy Blood Pressure
Heart Health
Impact
High effect
B+ Goal FitC Strength of SupportD CoverageA Formula Quality
Magnesium · 250 mg

Magnesium directly supports vascular tone and normal cardiac electrical function. Its cardiovascular relevance is established, especially when intake is inadequate.

The elemental amount reaches a useful range. Magnesium oxide has poor systemic absorption despite clear disclosure.

Study evidence
Magnesium Supportive 158 studies
General Health
Stress Resilience
General Health
Impact
High effect
A- Goal FitC Strength of SupportD+ CoverageA- Formula Quality
Magnesium · 250 mg

Magnesium is a foundational mineral involved in energy metabolism, nerve signaling, and muscle function. The stated amount is meaningful, but the product addresses only one main wellness pathway.

Magnesium oxide offers relatively poor absorption despite its clear elemental amount. People seeking systemic magnesium support may prefer a better-absorbed form such as glycinate or citrate.

Study evidence
Magnesium Supportive 114 studies
Stress Relief
Stress Relief
Impact
High effect
B- Goal FitC- Strength of SupportD- CoverageA- Formula Quality
Magnesium · 250 mg

Magnesium at 250 mg provides direct foundational support for normal nervous-system regulation and may help when low intake contributes to tension. The full amount comes from magnesium oxide, a form with poor systemic absorption.

The single-mineral design gives this pathway useful depth but does not add an adaptogen or direct calming amino acid. Digestive tolerance and practical benefit will depend heavily on the magnesium form.

Study evidence
Magnesium Supportive 13 studies
Cardiovascular Support
Cardiovascular Support
Impact
Moderate effect
B+ Goal FitC- Strength of SupportF CoverageB+ Formula Quality
Magnesium · 250 mg

Magnesium offers direct support for vascular tone and normal cardiac electrical activity at a useful stated amount. Strong evidence for the mineral supports the goal, especially when dietary intake is low.

Magnesium oxide has poor systemic absorption and sharply limits effective contribution. The compact two-mineral formula avoids padding, but the calcium addition does not solve the form-quality weakness.

Study evidence
Magnesium Supportive 123 studies
Digestive Health
Digestive Health
Impact
Moderate effect
C+ Goal FitC- Strength of SupportF CoverageB Formula Quality
Magnesium · 250 mg

The elemental magnesium amount may support bowel motility, but magnesium oxide is a weakly absorbed and less refined form. Its osmotic effect can still influence stool consistency in some users.

The simple label makes the intended mineral contribution easy to understand. Single-pathway action and the added calcium leave the formula narrow for broader digestive health.

Study evidence
Magnesium Supportive 50 studies
Bone Health
Bone Health
Impact
Moderate effect
C+ Goal FitD+ Strength of SupportD CoverageC+ Formula Quality
Magnesium · 250 mgCalcium · 65 mg

A substantial magnesium amount and a small calcium contribution provide focused mineral support. The absence of vitamin D, vitamin K, and stronger calcium coverage keeps the formula basic.

Elemental amounts are clearly stated and easy to assess. Magnesium oxide and calcium carbonate limit absorption quality despite the economical, simple design.

Study evidence
Calcium Supportive 144 studies
Magnesium Supportive 48 studies

Ingredients

IngredientAmount per serving
Calcium (Calcium Carbonate)
 65 mg
Magnesium (Magnesium Oxide)
 250 mg
Gluten Free Adults 18–50
Report overview
Magnesium (Magnesium Oxide) · 250 mg OverallScore50
F Active Ingredient Quality & BioavailabilityA- Dose, Safety & Label TransparencyD+ Value

Magnesium oxide provides the full stated amount but has poor systemic absorption. The elemental dose is clearly listed and sits in the preferred range, while the small calcium amount is unlikely to compete meaningfully. The very low serving cost is attractive, though users seeking absorption quality have better-form options.

View ingredientView products
Loading alternative details
91 Performance

Krebs Magnesium Potassium Complex

Nature's Way
Magnesium lysinate and malate provide favorable forms at a useful amount, with a modest potassium contribution. The better-absorbed form is more suitable for systemic magnesium replenishment than the original’s weaker form. The formula remains focused rather than comprehensive.
88 Performance

Magnesium Bisglycinate Powder

NOW
Magnesium bisglycinate supplies a well-absorbed form at a practical amount in an adjustable powder. The better-absorbed form is more suitable for systemic magnesium replenishment than the original’s weaker form. The single-mineral design does not address needs beyond magnesium.
85 Performance

Magnesium Bisglycinate 200 mg

Natural Factors
Magnesium bisglycinate provides a highly absorbable form at a moderate amount suited to routine use. The better-absorbed form is more suitable for systemic magnesium replenishment than the original’s weaker form. The focused formula offers no additional electrolyte or relaxation ingredients.
79 Budget

Magnesium Citrate Pure Powder

Best Naturals
Magnesium citrate in an adjustable powder provides useful absorption with a clearly stated amount. Its serving cost is comparable rather than lower; citrate may loosen stools in sensitive users.
70 Budget

Magnesium Caps 500 mg

Life Extension
Citrate, succinate, and named glycinate broaden the magnesium forms in a very economical capsule. No eligible candidate in this slot is cheaper than the original; the oxide portion lowers average absorption, and the large amount may cause diarrhea or cramping.
74 Budget

Potassium + Magnesium

Nutricost
Magnesium citrate with a modest potassium addition creates a simple two-mineral electrolyte formula. No eligible candidate in this slot is cheaper than the original; potassium is only a supporting amount, and citrate may loosen stools in sensitive users.
80 Value

Magnesium Bisglycinate Chelate

Healthy Origins
TRAACS magnesium bisglycinate combines premium form quality, a useful elemental amount, and a clean powder format. The serving costs more, so the value advantage depends on prioritizing form quality. The formula is narrow, and supplied customer satisfaction is less convincing than its ingredient quality.
78 Value

Magnesium Citrate 420 mg

Nutricost
A substantial magnesium citrate amount offers useful absorption in a focused, economical formula. The serving costs more, so the value advantage depends on prioritizing form quality. The higher amount may loosen stools or cause abdominal discomfort in sensitive users.
77 Value

Magnesium Citrate 200 mg

The Vitamin Shoppe
A moderate magnesium citrate amount provides practical daily supplementation in a simple tablet. The serving costs more, so the value advantage depends on prioritizing form quality. Tablet excipients and complete directions are not supplied, and citrate may affect digestive tolerance.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Role of magnesium supplementation in the treatment of depression: A randomized clinical trial.
    Tarleton EK; Littenberg B; MacLean CD; Kennedy AG; Daley C · PloS one · 2017
    Randomized trial126 participantsStress Relief forMagnesium
  2. Examining the Effects of Supplemental Magnesium on Self-Reported Anxiety and Sleep Quality: A Systematic Review.
    Rawji A; Peltier MR; Mourtzanakis K; Awan S; Rana J; Pothen NJ; Afzal S · Cureus · 2024
    Systematic review15 studies pooledStress Relief forMagnesium
  3. An update on magnesium and bone health.
    Rondanelli M; Faliva MA; Tartara A; Gasparri C; Perna S; Infantino V; Riva A; Petrangolini G; Peroni G · Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2022
    Narrative reviewBone Health forMagnesium
  4. Circulating and dietary magnesium and risk of cardiovascular disease: a systematic review and meta-analysis of prospective studies.
    Del Gobbo LC; Imamura F; Wu JH; de Oliveira Otto MC; Chiuve SE; Mozaffarian D · The American journal of clinical nutrition · 2013
    Meta-analysis313,041 participants16 studies pooledCardiovascular Support forMagnesium
  5. Effects of long-term magnesium supplementation on endothelial function and cardiometabolic risk markers: A randomized controlled trial in overweight/obese adults.
    Joris PJ; Plat J; Bakker SJ; Mensink RP · Scientific reports · 2018
    Randomized trial52 participantsCardiovascular Support forMagnesium
  6. The effect of food, vitamin, or mineral supplements on chronic constipation in adults: A systematic review and meta-analysis of randomized controlled trials.
    van der Schoot A; Creedon A; Whelan K; Dimidi E · Neurogastroenterology and motility · 2023
    Meta-analysis787 participants8 studies pooledDigestive Health forMagnesium
  7. Diagnosis of magnesium-induced diarrhea.
    Fine KD; Santa Ana CA; Fordtran JS · The New England journal of medicine · 1991
    Clinical trial19 participantsDigestive Health forMagnesium
  8. What is the impact of daily oral supplementation of vitamin D3 (cholecalciferol) plus calcium on the incidence of hip fracture in older people? A systematic review and meta-analysis.
    Manoj P; Derwin R; George S · International journal of older people nursing · 2023
    Meta-analysis12,620 participants7 studies pooledBone Health forCalcium
  9. Calcium supplementation prevents seasonal bone loss and changes in biochemical markers of bone turnover in elderly New England women: a randomized placebo-controlled trial.
    Storm D; Eslin R; Porter ES; Musgrave K; Vereault D; Patton C; Kessenich C; Mohan S; Chen T; Holick MF; Rosen CJ · The Journal of clinical endocrinology and metabolism · 1998
    Randomized trial60 participantsBone Health forCalcium
  10. The effects of calcium supplementation (milk powder or tablets) and exercise on bone density in postmenopausal women.
    Prince R; Devine A; Dick I; Criddle A; Kerr D; Kent N; Price R; Randell A · Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 1995
    Randomized trial168 participantsBone Health forCalcium
  11. The efficacy of calcium supplementation alone in elderly Thai women over a 2-year period: a randomized controlled trial.
    Rajatanavin R; Chailurkit L; Saetung S; Thakkinstian A; Nimitphong H · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2014
    Randomized trial404 participantsBone Health forCalcium
  12. Calcium-enriched foods and bone mass growth in prepubertal girls: a randomized, double-blind, placebo-controlled trial.
    Bonjour JP; Carrie AL; Ferrari S; Clavien H; Slosman D; Theintz G; Rizzoli R · The Journal of clinical investigation · 1997
    Randomized trial149 participantsBone Health forCalcium
  13. Association between Serum Magnesium and Fractures: A Systematic Review and Meta-Analysis of Observational Studies.
    Dominguez LJ; Veronese N; Ciriminna S; Pérez-Albela JL; Vásquez-López VF; Rodas-Regalado S; Di Bella G; Parisi A; Tagliaferri F; Barbagallo M · Nutrients · 2023
    Meta-analysis119,755 participants4 studies pooledBone Health forMagnesium
  14. Bioabsorbable Magnesium-Based Materials Potential and Safety in Bone Surgery: A Systematic Review.
    Hung CH; Kwok YC; Yip J; Wong HH; Leung YY · Craniomaxillofacial trauma & reconstruction · 2025
    Systematic review386 participants8 studies pooledBone Health forMagnesium
  15. Vascularized bone grafting fixed by biodegradable magnesium screw for treating osteonecrosis of the femoral head.
    Zhao D; Huang S; Lu F; Wang B; Yang L; Qin L; Yang K; Li Y; Li W; Wang W; Tian S; Zhang X; Gao W; Wang Z; Zhang Y; Xie X; Wang J; Li J · Biomaterials · 2016
    Randomized trial48 participantsBone Health forMagnesium
  16. Sex-specific differences in the association of magnesium intake with femoral neck bone mineral density among older adults.
    Wang B; Tan X; Yao X; Zhu Z · Endocrine connections · 2025
    Cross-sectional study1,343 participantsBone Health forMagnesium
  17. Magnesium and the risk of cardiovascular events: a meta-analysis of prospective cohort studies.
    Qu X; Jin F; Hao Y; Li H; Tang T; Wang H; Yan W; Dai K · PloS one · 2013
    Meta-analysis532,979 participants19 studies pooledCardiovascular Support forMagnesium
  18. Quantitative Association Between Serum/Dietary Magnesium and Cardiovascular Disease/Coronary Heart Disease Risk: A Dose-Response Meta-analysis of Prospective Cohort Studies.
    Zhao L; Hu M; Yang L; Xu H; Song W; Qian Y; Zhao M · Journal of cardiovascular pharmacology · 2020
    Meta-analysis544,581 participants18 studies pooledCardiovascular Support Heart Health forMagnesium
  19. Comparative Efficacy of Nutraceuticals on Endothelial Function: A Systematic Review and Network Meta-Analysis.
    Norouzzadeh M; Rashedi MH; Mahdavi-Mazdeh G; Kosari A; Shahinfar H · Current atherosclerosis reports · 2026
    Meta-analysisCardiovascular Support Heart Health forMagnesium
  20. Serum magnesium, mortality, and cardiovascular disease in chronic kidney disease and end-stage renal disease patients: a systematic review and meta-analysis.
    Xiong J; He T; Wang M; Nie L; Zhang Y; Wang Y; Huang Y; Feng B; Zhang J; Zhao J · Journal of nephrology · 2020
    Meta-analysis200,934 participants20 studies pooledCardiovascular Support forMagnesium
  21. Efficacy of oral magnesium therapy in the treatment of chronic constipation in spastic cerebral palsy children: a randomized controlled trial.
    Hassanein SMA; Deifallah SM; Bastawy HA · World journal of pediatrics : WJP · 2021
    Randomized trial100 participantsDigestive Health forMagnesium
  22. Ca:Mg ratio, medium-chain fatty acids, and the gut microbiome.
    Fan L; Zhu X; Sun S; Yu C; Huang X; Ness R; Dugan LL; Shu L; Seidner DL; Murff HJ; Fodor AA; Azcarate-Peril MA; Shrubsole MJ; Dai Q · Clinical nutrition (Edinburgh, Scotland) · 2022
    Randomized trial240 participantsDigestive Health forMagnesium
  23. The Magnesium-Rich Formula for Functional Constipation in Infants: a Randomized Comparator-Controlled Study.
    Benninga MA; MENA Infant Constipation Study Group; Vandenplas Y · Pediatric gastroenterology, hepatology & nutrition · 2022
    Randomized trial286 participantsDigestive Health forMagnesium
  24. A Randomized Double-blind Placebo-controlled Trial on the Effect of Magnesium Oxide in Patients With Chronic Constipation.
    Mori S; Tomita T; Fujimura K; Asano H; Ogawa T; Yamasaki T; Kondo T; Kono T; Tozawa K; Oshima T; Fukui H; Kimura T; Watari J; Miwa H · Journal of neurogastroenterology and motility · 2022
    Randomized trial34 participantsDigestive Health forMagnesium
  25. Magnesium treatment increases gut microbiome synthesizing vitamin D and inhibiting colorectal cancer: results from a double-blind precision-based randomized placebo-controlled trial.
    Sun E; Zhu X; Ness RM; Murff HJ; Sun S; Yu C; Fan L; Azcarate-Peril MA; Shrubsole MJ; Dai Q · The American journal of clinical nutrition · 2025
    Randomized trial240 participantsDigestive Health forMagnesium
  26. Magnesium-L-threonate improves sleep quality and daytime functioning in adults with self-reported sleep problems: A randomized controlled trial.
    Hausenblas HA; Lynch T; Hooper S; Shrestha A; Rosendale D; Gu J · Sleep medicine: X · 2025
    Randomized trial80 participantsEnergy forMagnesium
  27. Total magnesium intake and risk of frailty in older women.
    Struijk EA; Fung TT; Bischoff-Ferrari HA; Willett WC; Lopez-Garcia E · Journal of cachexia, sarcopenia and muscle · 2024
    Cohort study81,524 participantsEnergy forMagnesium
  28. Red blood cell magnesium and chronic fatigue syndrome.
    Cox IM; Campbell MJ; Dowson D · Lancet (London, England) · 1991
    Randomized trial32 participantsEnergy forMagnesium
  29. Exercise, magnesium and immune function.
    Laires MJ; Monteiro C · Magnesium research · 2008
    Narrative reviewEnergy forMagnesium
  30. Perioperative systemic magnesium to minimize postoperative pain: a meta-analysis of randomized controlled trials.
    De Oliveira GS; Castro-Alves LJ; Khan JH; McCarthy RJ · Anesthesiology · 2013
    Meta-analysis1,257 participants20 studies pooledGeneral Health forMagnesium
  31. Long-term outcome after intravenous magnesium sulphate in suspected acute myocardial infarction: the second Leicester Intravenous Magnesium Intervention Trial (LIMIT-2).
    Woods KL; Fletcher S · Lancet (London, England) · 1994
    Randomized trial2,316 participantsGeneral Health forMagnesium
  32. Association of magnesium sulfate use with mortality in critically ill patients with sepsis: a retrospective propensity score-matched cohort study.
    Gu WJ; Duan XJ; Liu XZ; Cen Y; Tao LY; Lyu J; Yin HY · British journal of anaesthesia · 2023
    Cohort study10,999 participantsGeneral Health forMagnesium
  33. Hypomagnesemia and Mortality in Incident Hemodialysis Patients.
    Li L; Streja E; Rhee CM; Mehrotra R; Soohoo M; Brunelli SM; Kovesdy CP; Kalantar-Zadeh K · American journal of kidney diseases : the official journal of the National Kidney Foundation · 2016
    Cohort study9,359 participantsGeneral Health forMagnesium
  34. The effects of magnesium supplementation on abnormal uterine bleeding, alopecia, quality of life, and acne in women with polycystic ovary syndrome: a randomized clinical trial.
    Jaripur M; Ghasemi-Tehrani H; Askari G; Gholizadeh-Moghaddam M; Clark CCT; Rouhani MH · Reproductive biology and endocrinology : RB&E · 2022
    Randomized trial64 participantsGeneral Health forMagnesium
  35. Effects of magnesium supplementation on improving hyperglycemia, hypercholesterolemia, and hypertension in type 2 diabetes: A pooled analysis of 24 randomized controlled trials.
    Xu L; Li X; Wang X; Xu M · Frontiers in nutrition · 2023
    Meta-analysis1,325 participants24 studies pooledHeart Health forMagnesium
  36. The effect of lowering blood pressure by magnesium supplementation in diabetic hypertensive adults with low serum magnesium levels: a randomized, double-blind, placebo-controlled clinical trial.
    Guerrero-Romero F; Rodríguez-Morán M · Journal of human hypertension · 2009
    Randomized trial82 participantsHeart Health forMagnesium
  37. Positive effects of magnesium supplementation in metabolic syndrome.
    Kisters S; Kisters K; Werner T; Vormann J; Tokmak F; Westhoff T; Gröber U; Predel HG; Reuter H · International journal of clinical pharmacology and therapeutics · 2024
    Randomized trial54 participantsHeart Health forMagnesium
  38. Effects of Intravenous Esketamine or Magnesium Sulfate on Early Postoperative Negative Emotions and Pain in Patients Undergoing Endoscopic Sinus Surgery: A Randomized Controlled Trial.
    Wang L; Zhou J; Liu Q; Qian K; Wang L; Xie C · Therapeutics and clinical risk management · 2026
    Randomized trial137 participantsStress Relief forMagnesium
  39. Effect of short-term magnesium supplementation on anxiety, depression and sleep quality in patients after open-heart surgery.
    Saba S; Faizi F; Sepandi M; Nehrir B · Magnesium research · 2022
    Non-randomized trial60 participantsStress Relief forMagnesium
  40. Effects of dry needling compared to magnesium infiltration in trigger points for patients with myofascial pain syndrome: a randomized controlled study in Tunisia.
    Dhouibi J; Moncer R; Kalbousi N; Gaddour M; Laayouni S; Ouanes W; Kacem B; Jemni S · Korean journal of family medicine · 2026
    Randomized trial45 participantsStress Relief forMagnesium
  41. Effect of magnesium and vitamin B6 supplementation on mental health and quality of life in stressed healthy adults: Post-hoc analysis of a randomised controlled trial.
    Noah L; Dye L; Bois De Fer B; Mazur A; Pickering G; Pouteau E · Stress and health : journal of the International Society for the Investigation of Stress · 2021
    Randomized trialStress Relief forMagnesium