Product Image

B-100

NOW
4.8
★ ★ ★ ★ ★
(14606 ratings)
Thiamin 100 mg
Niacin 100 mg
Riboflavin 100 mg
PABA 10 mg
Vitamin B5 100 mg
Choline 10 mg
Vitamin B12 100 mcg
Product Image
Score75
High amounts of most B vitamins are convenient, but the supplied label omits vitamin B6 and relies largely on conventional forms.
How scoring works
Quantity:100 Capsule(s) • (100 servings)
Goals:
Energy
General Health
Metabolism Boost

Score 75

High amounts of most B vitamins are convenient, but the supplied label omits vitamin B6 and relies largely on conventional forms.
How scoring works

Also available as

3 options
50.00mg • 100 Capsule(s) servings 50.00mg • 100 Capsule(s) • 100 servings $8.00 ($0.08 per serving) 50.00mg • 100 Tablet(s) servings 50.00mg • 100 Tablet(s) • 100 servings $11.60 ($0.11 per serving) 250 servings 1 Veg Capsule(s) • 250 Capsule(s) • 250 servings $30.95 ($0.12 per serving)
$13.02($0.13 per serving)
Pure Formulas
$ 16.14
Walmart
$ 13.02
Vitacost
$ 17.14
Daily Vita
$ 16.20
iHerb
$ 17.14
Amazon
$ 13.02
Report prices

Analysis

Thiamine, riboflavin, niacinamide, folate, B12, biotin, and pantothenic acid are all present at substantial amounts. Clear dose disclosure and a simple capsule format make the listed portion easy to assess.

Vitamin B6 is absent from the supplied ingredient information, so the profile is not complete despite the B-100 positioning. Most listed forms are also conventional, including cyanocobalamin, and the folate form is not specified.

Choline, inositol, and PABA are included at only 10 mg each and add little functional depth. It may fit someone seeking the specifically listed nutrients, but buyers expecting a complete B-complex should verify the current label first.

Who is it for
  • Adults seeking high amounts of the listed B vitamins
  • Capsule users who can verify the current label
Best for
  • High-potency thiamine and riboflavin
  • Broad coverage apart from the missing B6 listing

Pros

  • Substantial amounts of most B vitamins
  • Clearly stated listed doses
  • Convenient capsule format
  • Long bottle supply

Cons

  • Vitamin B6 is not listed in the supplied data
  • Uses conventional B12
  • Folate form is unspecified
  • Extras are minimally dosed

Warnings

  • The supplied ingredient list does not include vitamin B6; people choosing it as a complete B-complex should confirm the current package label before use.

Nutrient quality

62 Moderate impact

Substantial listed B-vitamin amounts support energy metabolism. Conventional forms, missing vitamin B6, and token secondary additions make the panel less complete.

Ingredient transparency

81 Highest impact

The listed actives have stated amounts and no proprietary blend appears. Excipients, daily-use directions, and clarity around the missing vitamin B6 entry remain absent.

Customer satisfaction

72 High impact

The average rating is strong and the large evidence base makes it more dependable. No specific feedback is supplied to judge repeated complaints or alignment with the intended use.

Value for money

85 Highest impact

Low serving cost supports strong value for the listed vitamin coverage. Missing vitamin B6 and several token additions reduce value as a complete B-complex.

Report analysis

Goals

Energy
Energy
Impact
High effect
B+ Goal FitB- Strength of SupportC CoverageA Formula Quality
Vitamin B5 · 100 mgRiboflavin · 100 mgThiamin · 100 mgVitamin B12 · 100 mcg

High-potency thiamin, riboflavin, niacin, pantothenic acid, and B12 support several steps in cellular energy metabolism. The simple capsule provides focused metabolic cofactors without a stimulant component.

The provided label does not list vitamin B6, and cyanocobalamin remains below the targeted B12 range for energy support. It suits focused B-vitamin supplementation better than comprehensive support for stamina, focus, and stress resilience.

Study evidence
Riboflavin Mixed 6 studies
Thiamin Disputed 12 studies
Vitamin B12 Disputed 14 studies
General Health
Daily Energy Vitality
General Health
Impact
High effect
A- Goal FitD+ Strength of SupportC CoverageB- Formula Quality
Folate · 680 mcg DFEVitamin B12 · 100 mcg

A broad B-vitamin formula supports normal energy metabolism and helps cover several foundational nutrient needs. The nutrient roles are well established, but very large amounts are not automatically more useful for routine wellness.

Cyanocobalamin and standard vitamin forms limit form quality, while small choline and inositol amounts add little practical support. The formula suits targeted high-potency B-vitamin use better than balanced daily nutrition.

Study evidence
Vitamin B12 Adverse 66 studies
Metabolism Boost
Metabolism Boost
Impact
High effect
C Goal FitC+ Strength of SupportD+ CoverageB Formula Quality
Biotin · 100 mcgNiacin · 100 mgVitamin B12 · 100 mcgRiboflavin · 100 mgThiamin · 100 mgVitamin B5 · 100 mg

The concentrated blend supports several B-vitamin-dependent energy reactions through thiamine, riboflavin, niacin, pantothenic acid, and related nutrients. Its effect is mainly nutritional support rather than direct stimulation of energy expenditure.

Substantial disclosed amounts give the formula depth, but the supplied ingredient data do not list vitamin B6. That omission leaves a notable gap in an otherwise coherent B-complex and does not add thermogenic, thyroid, or glycemic coverage.

Study evidence
Niacin Supportive 17 studies
Riboflavin Mixed 5 studies
Thiamin Supportive 11 studies
Vitamin B5 Supportive 12 studies

Ingredients

IngredientAmount per serving
Thiamine (Thiamine Hydrochloride, Vitamin B1)
 100 mg
Riboflavin (Vitamin B2)
 100 mg
Niacin (Niacinamide, Vitamin B3)
 100 mg
Folate
680 mcg DFE
Vitamin B12 (Cyanocobalamin)
 100 mcg
Biotin
100 mcg
Pantothenic Acid (Calcium Pantothenate)
 100 mg
Choline (Choline Bitartrate)
 10 mg
Inositol
10 mg
PABA
10 mg
Gluten Free Adults 18–50 Vegan Kosher Dairy Free Vegetarian
Report overview
Thiamin (Thiamine Hydrochloride, Vitamin B1) · 100 mg OverallScore88
B- Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyA+ Value

A high-potency thiamin dose uses a standard water-soluble form and is fully disclosed. The conventional capsule provides ordinary delivery quality without a premium absorption system. Value is excellent for a broad formula priced below the collection norm.

View ingredientView products
Niacin (Niacinamide, Vitamin B3) · 100 mg OverallScore82
B+ Active Ingredient Quality & BioavailabilityA Dose, Safety & Label TransparencyC Value

The B-complex provides a substantial niacinamide amount for general nutritional use. A standard capsule offers no special release control, while the clearly disclosed form keeps classic flushing unlikely. Its serving cost is favorable for the amount and the wider B-vitamin profile.

View ingredientView products
Riboflavin (Vitamin B2) · 100 mg OverallScore77
D- Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyA+ Value

Standard riboflavin requires enzymatic conversion before it becomes metabolically active, while the capsule should dissolve readily. The amount reaches the high-potency range for metabolic support. The low serving cost makes the clearly stated dose highly efficient.

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Loading alternative details
81 Performance

Activated B-Complex High Bioavailability

Swanson
<p>Active riboflavin, P-5-P, methylfolate, methylcobalamin, benfotiamine, and pantethine provide much stronger form quality than the original. Vitamin B6 remains high for prolonged use, while choline and biotin are modest.</p>
79 Performance

CoEnzyme B-Complex

KAL
<p>Active and conventional forms provide complete coverage, including vitamin B6, with more restrained amounts than a B-100 formula. The chewable adds carbohydrates and uses mixed B12 forms, but dose balance is better than the original.</p>
81 Performance

Coenzyme B-Complex Caps

Country Life
<p>Coenzyme forms, methylfolate, methylcobalamin, dibencozide, pantethine, and choline create a more refined and complete formula. Vitamin B6 remains elevated, but the original’s missing B6 and conventional forms are resolved.</p>
77 Budget

B-50

NOW
<p>A large supply delivers the core B vitamins, including the vitamin B6 missing from the supplied original label, at lower serving cost. Basic forms and high pyridoxine limit long-term daily suitability.</p>
77 Budget

B-50 Complex 50 mg

Source Naturals
<p>Broad B-vitamin coverage adds the missing vitamin B6 while keeping serving value favorable. High folate and vitamin B6 reduce dose balance, and the forms are mostly conventional.</p>
76 Budget

Hi Potency B Complex

Natural Factors
<p>A complete B-complex adds vitamin B6 and offers a long supply at slightly lower serving cost. High folate and pyridoxine amounts are unnecessarily aggressive for routine unsupervised use.</p>
76 Value

B-100

NOW
<p>The longer-size version adds the vitamin B6 absent from the supplied original panel while retaining broad B-100 coverage at slightly better serving value. Very high pyridoxine and conventional forms remain important long-term drawbacks.</p>
72 Value

Complete B 100 mg

Natural Factors
<p>A complete B-100 profile adds vitamin B6, more biotin, choline, inositol, and PABA at reasonable value. Conventional forms and excessive pyridoxine make it appropriate only for targeted high-potency use.</p>
67 Value

B-Complex 100

Bluebonnet
<p>A full B-100 formula adds vitamin B6 and increases choline and inositol while remaining relatively inexpensive. Duplicate label entries, basic forms, and aggressive pyridoxine weaken quality compared with the original.</p>
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Relationship between serum B12 concentrations and mortality: experience in NHANES.
    Wolffenbuttel BHR; Heiner-Fokkema MR; Green R; Gans ROB · BMC medicine · 2021
    Cohort study24,262 participantsGeneral Health forVitamin B12
  2. Holo-transcobalamin is not associated with the risk of all-cause mortality in the general population.
    Stürmer P; Strathmann EA; Rimbach G; Weber KS; Lieb W · Clinical nutrition ESPEN · 2024
    Cohort study862 participantsGeneral Health forVitamin B12
  3. The origin of vitamin B12 levels and risk of all-cause, cardiovascular and cancer specific mortality: A systematic review and dose-response meta-analysis.
    Liu K; Yang Z; Lu X; Zheng B; Wu S; Kang J; Sun S; Zhao J · Archives of gerontology and geriatrics · 2024
    Meta-analysis92,346 participants22 studies pooledGeneral Health forVitamin B12
  4. Disorders of flavin adenine dinucleotide metabolism: MADD and related deficiencies.
    Mereis M; Wanders RJA; Schoonen M; Dercksen M; Smuts I; van der Westhuizen FH · The international journal of biochemistry & cell biology · 2024
    Systematic reviewMetabolism Boost forRiboflavin
  5. Anaemia during pregnancy: could riboflavin deficiency be implicated?
    Duffy B; McNulty H; Ward M; Pentieva K · The Proceedings of the Nutrition Society · 2026
    Narrative reviewMetabolism Boost forRiboflavin
  6. Riboflavin and riboflavin-derived cofactors in adolescent girls with anorexia nervosa.
    Capo-chichi CD; Guéant JL; Lefebvre E; Bennani N; Lorentz E; Vidailhet C; Vidailhet M · The American journal of clinical nutrition · 1999
    Clinical trial34 participantsMetabolism Boost forRiboflavin
  7. Physicochemical properties of and volatile compounds in riboflavin fortified cloudy apple juice; study of its effect on job fatigue among Egyptian construction workers.
    Fouad S; Ibrahim GE; Hussein AMS; Ibrahim FA; El Gendy A · Heliyon · 2021
    Non-randomized trialEnergy forRiboflavin
  8. Vitamin B status in patients with chronic fatigue syndrome.
    Heap LC; Peters TJ; Wessely S · Journal of the Royal Society of Medicine · 1999
    Case-control study30 participantsEnergy forRiboflavin
  9. B-vitamins, related vitamers, and metabolites in patients with quiescent inflammatory bowel disease and chronic fatigue treated with high dose oral thiamine.
    Bager P; Hvas CL; Hansen MM; Ueland P; Dahlerup JF · Molecular medicine (Cambridge, Mass.) · 2023
    Observational studyEnergy forRiboflavin
  10. Metabolic features of chronic fatigue syndrome.
    Naviaux RK; Naviaux JC; Li K; Bright AT; Alaynick WA; Wang L; Baxter A; Nathan N; Anderson W; Gordon E · Proceedings of the National Academy of Sciences of the United States of America · 2024
    Case-control study84 participantsEnergy forRiboflavin
  11. Effectiveness of Riboflavin in Inherited Metabolic Diseases: A Systematic Review
    Bregje Jaeger, Nina N Stolwijk, Femke Aaldering, Charlotte A Ruys, Marije Smits, Nicole I Wolf, Carla E M Hollak, Annet M Bosch · Journal of Inherited Metabolic Disease · 2026
    Systematic review381 studies pooledEnergy Metabolism Boost forRiboflavin
  12. Influence of thiamin supplementation on the health and general well-being of an elderly Irish population with marginal thiamin deficiency.
    Smidt LJ; Cremin FM; Grivetti LE; Clifford AJ · Journal of gerontology · 1991
    Randomized trial80 participantsEnergy forThiamin
  13. Randomised clinical trial: high-dose oral thiamine versus placebo for chronic fatigue in patients with quiescent inflammatory bowel disease.
    Bager P; Hvas CL; Rud CL; Dahlerup JF · Alimentary pharmacology & therapeutics · 2021
    Randomized trial40 participantsEnergy forThiamin
  14. Dietary reference values for thiamin.
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA); Turck D; Bresson JL; Burlingame B; Dean T; Fairweather-Tait S; Heinonen M; Hirsch-Ernst KI; Mangelsdorf I; McArdle HJ; Naska A; Nowicka G; Pentieva K; Sanz Y; Siani A; Sjödin A; Stern M; Tomé D; Van Loveren H; Vinceti M; Willatts P; Lamberg-Allardt C; Przyrembel H; Tetens I; Gudelj Rakic J; Ioannidou S; de Sesmaisons-Lecarré A; Forss AC; Neuhäuser-Berthold M · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusEnergy forThiamin
  15. Effects of thiamine supplementation on exercise-induced fatigue.
    Suzuki M; Itokawa Y · Metabolic brain disease · 1996
    Randomized trial16 participantsEnergy forThiamin
  16. Long-term maintenance treatment with 300 mg thiamine for fatigue in patients with inflammatory bowel disease: results from an open-label extension of the TARIF study.
    Bager P; Hvas CL; Rud CL; Dahlerup JF · Scandinavian journal of gastroenterology · 2022
    Randomized trialEnergy forThiamin
  17. A new perspective on vitamin B12 deficiency in rheumatology: a case-based review.
    Dułak NA; Rytlewska M; Jaskólska M; Chmielewski M · Rheumatology international · 2024
    Case series3 participantsEnergy forVitamin B12
  18. Effects of Vitamin B12 Supplementation on Cognitive Function, Depressive Symptoms, and Fatigue: A Systematic Review, Meta-Analysis, and Meta-Regression.
    Markun S; Gravestock I; Jäger L; Rosemann T; Pichierri G; Burgstaller JM · Nutrients · 2021
    Meta-analysis6,276 participants16 studies pooledEnergy forVitamin B12
  19. Patients' experiences with methylcobalamin injections in amyotrophic lateral sclerosis.
    Zubair AS; Saab L; Scharer K; Khokhar B · Brain circulation · 2024
    Qualitative study5 participantsEnergy forVitamin B12
  20. Cobalamin deficiency: clinical picture and radiological findings.
    Briani C; Dalla Torre C; Citton V; Manara R; Pompanin S; Binotto G; Adami F · Nutrients · 2014
    Narrative reviewEnergy forVitamin B12
  21. Vitamin B12 Deficiency: Common Questions and Answers.
    Patel H; McGuirk R · American family physician · 2025
    Narrative reviewEnergy forVitamin B12
  22. Oral Vitamin B12 versus Placebo for the Prevention of Chemotherapy-Induced Peripheral Neuropathy in Gynecological Cancer Patients: A Randomized, Double-Blind, Placebo-Controlled Trial.
    Insin P; Chaiwongsa T; Prueksaritanond N · Asian Pacific journal of cancer prevention : APJCP · 2026
    Randomized trial40 participantsGeneral Health forVitamin B12
  23. Vitamin B12 Supplementation in Diabetic Neuropathy: A 1-Year, Randomized, Double-Blind, Placebo-Controlled Trial.
    Didangelos T; Karlafti E; Kotzakioulafi E; Margariti E; Giannoulaki P; Batanis G; Tesfaye S; Kantartzis K · Nutrients · 2021
    Randomized trial90 participantsGeneral Health forVitamin B12
  24. A single-center randomized controlled trial of local methylcobalamin injection for subacute herpetic neuralgia.
    Xu G; Lv ZW; Feng Y; Tang WZ; Xu GX · Pain medicine (Malden, Mass.) · 2014
    Randomized trial98 participantsGeneral Health forVitamin B12
  25. Local Injection of Methylcobalamin Combined with Lidocaine for Acute Herpetic Neuralgia.
    Xǔ G; Xu S; Tang WZ; Xú G; Cheng C; Xu J · Pain medicine (Malden, Mass.) · 2017
    Randomized trial204 participantsGeneral Health forVitamin B12
  26. The Effect of Vitamin B12 and Folic Acid Supplementation on Serum Homocysteine, Anemia Status and Quality of Life of Patients with Multiple Sclerosis.
    Nozari E; Ghavamzadeh S; Razazian N · Clinical nutrition research · 2022
    Clinical trial50 participantsGeneral Health forVitamin B12
  27. Niacin and contribution to normal energy-yielding metabolism: evaluation of a health claim pursuant to Article 14 of Regulation (EC) No 1924/2006.
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusMetabolism Boost forNiacin
  28. Targeted Microbiome Intervention by Microencapsulated Delayed-Release Niacin Beneficially Affects Insulin Sensitivity in Humans.
    Fangmann D; Theismann EM; Türk K; Schulte DM; Relling I; Hartmann K; Keppler JK; Knipp JR; Rehman A; Heinsen FA; Franke A; Lenk L; Freitag-Wolf S; Appel E; Gorb S; Brenner C; Seegert D; Waetzig GH; Rosenstiel P; Schreiber S; Schwarz K; Laudes M · Diabetes care · 2018
    Clinical trialMetabolism Boost forNiacin
  29. The differential impact of three different NAD+ boosters on circulatory NAD and microbial metabolism in humans.
    Christen S; Redeuil K; Goulet L; Giner MP; Breton I; Rota R; Frézal A; Nazari A; Van den Abbeele P; Godin JP; Nutten S; Cuenoud B · Nature metabolism · 2026
    Randomized trial65 participantsMetabolism Boost forNiacin
  30. Effects of extended-release niacin on lipid profile and adipocyte biology in patients with impaired glucose tolerance.
    Linke A; Sonnabend M; Fasshauer M; Höllriegel R; Schuler G; Niebauer J; Stumvoll M; Blüher M · Atherosclerosis · 2009
    Randomized trial30 participantsMetabolism Boost forNiacin
  31. Effect of the antilipolytic nicotinic acid analogue acipimox on whole-body and skeletal muscle glucose metabolism in patients with non-insulin-dependent diabetes mellitus.
    Vaag A; Skött P; Damsbo P; Gall MA; Richter EA; Beck-Nielsen H · The Journal of clinical investigation · 1991
    Clinical trial12 participantsMetabolism Boost forNiacin
  32. Effects of riboflavin and folic acid supplementation on plasma homocysteine levels in healthy subjects.
    Chuang CZ; Boyles A; Legardeur B; Su J; Japa S; Lopez-S A · The American journal of the medical sciences · 2006
    Non-randomized trial34 participantsMetabolism Boost forRiboflavin
  33. Neurological, Psychiatric, and Biochemical Aspects of Thiamine Deficiency in Children and Adults.
    Dhir S; Tarasenko M; Napoli E; Giulivi C · Frontiers in psychiatry · 2026
    Narrative reviewMetabolism Boost forThiamin
  34. Plasma vitamin profiles and their associations with metabolic health and mental wellbeing in midlife Asian women.
    Tan KML; Tint MT; Cabral RM; Lau R; Kee MZL; Garg V; De Iorio M; Tan SSL; Eriksson JG · Scientific reports · 2026
    Cohort study662 participantsMetabolism Boost forThiamin
  35. High-resolution plasma metabolomics and thiamine status in critically Ill adult patients.
    Gundogan K; Nellis MM; Ozer NT; Ergul SS; Sahin GG; Temel S; Yuksel RC; Teeny S; Alvarez JA; Sungur M; Jones DP; Ziegler TR · Metabolomics : Official journal of the Metabolomic Society · 2024
    Cross-sectional study76 participantsMetabolism Boost forThiamin
  36. Pathophysiology, prevention, and treatment of beriberi after gastric surgery.
    Wilson RB · Nutrition reviews · 2021
    Narrative reviewMetabolism Boost forThiamin
  37. Red blood cell transketolase activity and the effect of thiamine supplementation in patients with chronic liver disease.
    Rossouw JE; Labadarios D; Krasner N; Davis M; Williams R · Scandinavian journal of gastroenterology · 1978
    Single-arm trialMetabolism Boost forThiamin
  38. Apolipoprotein E and sex modulate fatty acid metabolism in a prospective observational study of cognitive decline.
    González-Domínguez R; Castellano-Escuder P; Lefèvre-Arbogast S; Low DY; Du Preez A; Ruigrok SR; Lee H; Helmer C; Pallàs M; Urpi-Sarda M; Sánchez-Pla A; Korosi A; Lucassen PJ; Aigner L; Manach C; Thuret S; Samieri C; Andres-Lacueva C · Alzheimer's research & therapy · 2022
    Observational studyMetabolism Boost forVitamin B5
  39. Exploring auxotrophy and engineering vitamin B6 prototrophy in the acetogen Clostridium sp. AWRP.
    Kwon SJ; Lee J; Lee HS · Applied and environmental microbiology · 2024
    Clinical trialMetabolism Boost forVitamin B5
  40. Pantothenate utilization by Plasmodium as a target for antimalarial chemotherapy.
    Spry C; van Schalkwyk DA; Strauss E; Saliba KJ · Infectious disorders drug targets · 2010
    Narrative reviewMetabolism Boost forVitamin B5
  41. Optimum nutrition: thiamin, biotin and pantothenate.
    Bender DA · The Proceedings of the Nutrition Society · 1999
    Narrative reviewMetabolism Boost forVitamin B5
  42. Serum metabolites of hypertension among Chinese adolescents aged 12-17 years.
    Sun J; Ding W; Liu X; Zhao M; Xi B · Journal of human hypertension · 2022
    Other77 participantsMetabolism Boost forVitamin B5