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Vitamin K2 180 mcg

4.8
★ ★ ★ ★ ★
(356 ratings)
Vitamin K 180 mcg
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Score78
A clear, high-strength MK-7 formula offers good single-nutrient depth, but dry delivery and weak value hold it back.
How scoring works
Capsule
Quantity:90 Capsule(s) • (90 servings)
Goals:
General Health
Heart Health
Cardiovascular Support
Bone Health
Anti-Aging

Score 78

A clear, high-strength MK-7 formula offers good single-nutrient depth, but dry delivery and weak value hold it back.
How scoring works

Also available as

1 option
30 servings K 180 mcg • 30 Capsule(s) • 30 servings $27.99 ($0.93 per serving)
$69.99($0.77 per serving)
Vitacost
$ 77.99
iHerb
$ 76.99
Pure Formulas
$ 69.99
Report prices

Analysis

Menaquinone-7 is a long-acting vitamin K2 form, and the 180 mcg amount is substantial for daily calcium-handling support. The focused formula is easy to understand and avoids decorative ingredients.

The supplied label does not name a branded or verified all-trans source. A dry capsule also offers no built-in lipid carrier for a fat-soluble nutrient.

It fits adults who want a higher-strength K2-only product and already cover vitamin D, calcium, and magnesium elsewhere. Less expensive products provide similar MK-7 exposure.

Who is it for
  • Adults seeking higher-strength MK-7
  • People who already use vitamin D separately
  • Users wanting a focused K2 formula
Best for
  • Targeted vitamin K2 intake
  • Bone and vascular calcium handling
  • Simple single-active supplementation

Pros

  • Supplies 180 mcg of MK-7
  • Uses a long-acting K2 form
  • Clearly discloses the active amount
  • Avoids unrelated additions

Cons

  • Dry-capsule delivery gives no built-in fat source for this fat-soluble nutrient
  • The supplied label does not identify a branded or verified all-trans MK-7 source
  • Costs more than many comparable MK-7 options
  • Covers calcium handling but not the wider range of bone or cardiovascular pathways

Warnings

  • Vitamin K can counteract warfarin and other vitamin K antagonist anticoagulants; use requires prescriber-guided consistency.
  • Bile-acid sequestrants such as cholestyramine can reduce absorption of fat-soluble vitamin K; follow medication-specific spacing advice.
  • Fat-malabsorption conditions can make vitamin K uptake unreliable, so response may need clinical monitoring.

Nutrient quality

92 Highest impact

A well-regarded form and substantial amount create a focused high-potency supplement. The dose is more aggressive than necessary for many routine users.

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Ingredient transparency

84 Highest impact

The active form and amount are exceptionally clear with no hidden blend. Missing intake directions and capsule excipients are the only notable gaps.

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Customer satisfaction

69 High impact

Aggregate satisfaction is very strong and supported by a substantial evidence base. No firsthand experience details are supplied, so recurring complaints and purpose alignment cannot be checked.

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Value for money

60 Moderate impact

The formula has useful ingredients, but its positioning limits value. Many alternatives provide stronger practical value.

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Report analysis

Goals

General Health
General Health
Impact
Highest effect
A- Goal FitA+ Strength of SupportC CoverageA+ Formula Quality
Vitamin K · 180 mcg

Menaquinone-7 provides a preferred long-acting form of vitamin K2 for calcium regulation and bone support. The clearly stated amount offers strong depth for this focused foundational pathway.

A single nutrient cannot cover the wider range of daily wellness needs, but the streamlined design avoids low-value additions. Vitamin K2 can oppose warfarin and related vitamin K antagonist medicines, so users of those drugs need clinician-guided consistency.

Study evidence
Vitamin K Supportive 34 studies
Heart Health
Heart Health
Impact
Highest effect
B Goal FitA+ Strength of SupportC CoverageA+ Formula Quality
Vitamin K · 180 mcg

Vitamin K2 as MK-7 supports activation of proteins that help direct calcium away from blood vessels. The substantial amount and long-acting form provide strong single-pathway support.

Evidence is more established for biological markers of calcium handling than for preventing cardiovascular events. Vitamin K2 can oppose warfarin and other vitamin K antagonist anticoagulants, making unsupervised use inappropriate with those medicines.

Study evidence
Vitamin K Mixed 62 studies
Cardiovascular Support
Cardiovascular Support
Impact
Highest effect
B+ Goal FitA+ Strength of SupportC CoverageA+ Formula Quality
Vitamin K · 180 mcg

MK-7 vitamin K2 directly supports healthy calcium handling in blood vessels. The clearly disclosed amount and preferred form make it well aligned with long-term vascular support.

The formula addresses one cardiovascular pathway rather than lipids, blood flow, or rhythm. Vitamin K2 can interfere with warfarin and other vitamin K antagonist therapy, so users of those medicines need clinician-guided intake.

Study evidence
Vitamin K Supportive 40 studies
Bone Health
Bone Health
Impact
Highest effect
A Goal FitA+ Strength of SupportC- CoverageB+ Formula Quality
Vitamin K · 180 mcg

MK-7 vitamin K2 directly supports proteins that guide calcium into bone tissue. The fully stated form and meaningful amount make the formula well aligned with calcium-handling support.

The single-nutrient design does not provide calcium, vitamin D, magnesium, or the collagen matrix. MK-7 can reduce warfarin’s anticoagulant effect, so people using warfarin need clinician-guided, consistent vitamin K intake.

Study evidence
Vitamin K Supportive 78 studies
Anti-Aging
Anti-Aging
Impact
Highest effect
B Goal FitA+ Strength of SupportC- CoverageA+ Formula Quality
Vitamin K · 180 mcg

Menaquinone-7 supports bone strength and vascular calcium handling, both relevant to healthy aging. The 180 mcg amount is substantial and uses a preferred long-acting K2 form.

A single-ingredient design offers strong depth but no coverage of mitochondrial, inflammatory, or structural pathways beyond calcium regulation. Vitamin K2 can counteract warfarin and related vitamin K antagonists, making clinician-guided consistency important for users of those medicines.

Study evidence
Vitamin K Supportive 27 studies

Ingredients

IngredientAmount per serving
Vitamin K2 (Menaquinone-7)
 180 mcg
Adults 18–50
Report overview
Vitamin K (Menaquinone-7) · 180 mcg OverallScore75
C+ Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyD- Value

Generic MK-7 is clearly disclosed at an effective clinical amount. The dry capsule has no stated lipid or meal guidance, and no branded source is identified. The high cost yields only average value despite strong dosing.

View ingredientView products
Loading alternative details
86 Performance

Vitamin K2 MK-7 (Menaquinone-7) 90 mcg

Carlson
Compared with 180 mcg of MK-7 vitamin K2, the alternative provides 90 mcg of MK-7 vitamin K2, and the supplied analysis indicates stronger alignment with the Vitamin K collection. Its focused formula offers solid routine value, though vitamin K can conflict with warfarin and similar vitamin K antagonists.
87 Performance

Vitamin K2 as MK-7 100 mcg

Healthy Origins
Compared with 180 mcg of MK-7 vitamin K2, the alternative provides 100 mcg of MK-7 vitamin K2, and the supplied analysis indicates stronger alignment with the Vitamin K collection. Vitamin K2 can reduce the effect of warfarin-type anticoagulants.
87 Performance

Vitamin K2 100 mcg

SR Sports Research
Compared with 180 mcg of MK-7 vitamin K2, the alternative provides 100 mcg of MK-7 vitamin K2, and the supplied analysis indicates stronger alignment with the Vitamin K collection. Vitamin K2 can reduce the effect of warfarin-type anticoagulants, so intake changes require prescriber guidance.
88 Budget

Vitamin K2 MK-7 100 mcg

Nutricost
The supplied serving cost is lower, while the formula provides 100 mcg of MK-7 vitamin K2. Vitamin K2 can interfere with warfarin-type anticoagulants.
89 Budget

Mega D-3 5000 IU & MK-7 180 mcg

NOW
The supplied serving cost is lower, while the formula provides 125 mcg of vitamin D3 with 180 mcg of MK-7 vitamin K2. High vitamin D remains the main dosing limitation, while the dry capsule lacks stated fat-intake guidance.
85 Budget

Vitamin K2 MenaQ7 100 mcg

AN Amazing Nutrition Amazing Formulas
The supplied serving cost is lower, while the formula provides vitamin k2. Its vitamin K can counteract warfarin and related vitamin K antagonists, so people using those medicines need clinician-directed intake.
87 Value

MK-7 Vitamin K-2 100 mcg

NOW
100 mcg of MK-7 vitamin K2 offers a practical value trade-off because the supplied serving cost is lower and the value analysis is stronger. Its long supply supports strong value, though vitamin K can conflict with warfarin and similar vitamin K antagonists.
87 Value

Low Dose Vitamin K2 (MK-7) 45 mcg

Life Extension
45 mcg of MK-7 vitamin K2 offers a practical value trade-off because the supplied serving cost is lower and the value analysis is stronger. Its focused formula offers good routine value, though vitamin K can conflict with warfarin and similar vitamin K antagonists.
86 Value

Vitamin K2 MK-7 (Menaquinone-7) 90 mcg

Carlson
90 mcg of MK-7 vitamin K2 offers a practical value trade-off because the supplied serving cost is lower and the value analysis is stronger. Its focused formula offers solid routine value, though vitamin K can conflict with warfarin and similar vitamin K antagonists.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Three-year low-dose menaquinone-7 supplementation helps decrease bone loss in healthy postmenopausal women.
    Knapen MH; Drummen NE; Smit E; Vermeer C; Theuwissen E · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2014
    Randomized trial244 participantsBone Health forVitamin K
  2. Investigating the interrelationship of vitamin K and vitamin D status on bone density: results from the VITamin D and OmegA-3 TriaL.
    Chou SH; Booth SL; Cook NR; Kim E; Kotler G; Fu X; Buring JE; Manson JE; LeBoff MS · JBMR plus · 2026
    Randomized trial771 participantsBone Health forVitamin K
  3. Efficacy and safety of vitamin K2 for postmenopausal women with osteoporosis at a long-term follow-up: meta-analysis and systematic review.
    Zhou M; Han S; Zhang W; Wu D · Journal of bone and mineral metabolism · 2022
    Meta-analysis6,853 participants9 studies pooledBone Health forVitamin K
  4. Vitamin K status, cardiovascular disease, and all-cause mortality: a participant-level meta-analysis of 3 US cohorts.
    Shea MK; Barger K; Booth SL; Matuszek G; Cushman M; Benjamin EJ; Kritchevsky SB; Weiner DE · The American journal of clinical nutrition · 2020
    Meta-analysis3,891 participants3 studies pooledAnti-Aging General Health forVitamin K
  5. Topical Menaquinone‑7 (Vitamin K2, MK-7) as a Mitochondrial Bioenergetic Activator for Skin Anti-Aging: Mechanistic Evidence in Skin Cells and a Randomized Split-Face/Neck Study.
    Huang H; Wei R; Xu C; Liu C; Zhao S; Li Y; Wang M · ACS omega · 2026
    Randomized trial30 participantsAnti-Aging forVitamin K
  6. Vitamin K status and cognitive function in healthy older adults.
    Presse N; Belleville S; Gaudreau P; Greenwood CE; Kergoat MJ; Morais JA; Payette H; Shatenstein B; Ferland G · Neurobiology of aging · 2014
    Cross-sectional study320 participantsAnti-Aging forVitamin K
  7. High dephospho-uncarboxylated matrix Gla protein concentrations, a plasma biomarker of vitamin K, in relation to frailty: the Longitudinal Aging Study Amsterdam.
    Machado-Fragua MD; Hoogendijk EO; Struijk EA; Rodriguez-Artalejo F; Lopez-Garcia E; Beulens JW; van Ballegooijen AJ · European journal of nutrition · 2021
    Cohort study644 participantsAnti-Aging forVitamin K
  8. Vitamin K Concentration and Cognitive Status in Elderly Patients on Anticoagulant Therapy: A Pilot Study.
    Alisi L; Cafolla C; Gentili A; Tartaglione S; Curini R; Cafolla A · Journal of aging research · 2022
    Cross-sectional study85 participantsAnti-Aging forVitamin K
  9. Vitamin K and the prevention of fractures: systematic review and meta-analysis of randomized controlled trials.
    Cockayne S; Adamson J; Lanham-New S; Shearer MJ; Gilbody S; Torgerson DJ · Archives of internal medicine · 2006
    Meta-analysis13 studies pooledBone Health forVitamin K
  10. Effect of combined administration of vitamin D3 and vitamin K2 on bone mineral density of the lumbar spine in postmenopausal women with osteoporosis.
    Iwamoto J; Takeda T; Ichimura S · Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association · 2001
    Randomized trial92 participantsBone Health forVitamin K
  11. Low-dose vitamin K2 (MK-4) supplementation for 12 months improves bone metabolism and prevents forearm bone loss in postmenopausal Japanese women.
    Koitaya N; Sekiguchi M; Tousen Y; Nishide Y; Morita A; Yamauchi J; Gando Y; Miyachi M; Aoki M; Komatsu M; Watanabe F; Morishita K; Ishimi Y · Journal of bone and mineral metabolism · 2015
    Randomized trial48 participantsBone Health forVitamin K
  12. Vitamin K Intake and Atherosclerotic Cardiovascular Disease in the Danish Diet Cancer and Health Study.
    Bellinge JW; Dalgaard F; Murray K; Connolly E; Blekkenhorst LC; Bondonno CP; Lewis JR; Sim M; Croft KD; Gislason G; Torp-Pedersen C; Tjønneland A; Overvad K; Hodgson JM; Schultz C; Bondonno NP · Journal of the American Heart Association · 2021
    Cohort study53,372 participantsCardiovascular Support Heart Health forVitamin K
  13. Menaquinone-7 supplementation improves arterial stiffness in healthy postmenopausal women. A double-blind randomised clinical trial.
    Knapen MH; Braam LA; Drummen NE; Bekers O; Hoeks AP; Vermeer C · Thrombosis and haemostasis · 2016
    Randomized trial244 participantsCardiovascular Support Heart Health forVitamin K
  14. Effects of One-Year Menaquinone-7 Supplementation on Vascular Stiffness and Blood Pressure in Post-Menopausal Women.
    de Vries F; Bittner R; Maresz K; Machuron F; Gåserød O; Jeanne JF; Schurgers LJ · Nutrients · 2025
    Randomized trial165 participantsCardiovascular Support forVitamin K
  15. Dietary Vitamin K1 Intake and Incident Aortic Valve Stenosis.
    Schultz CJ; Dalgaard F; Bellinge JW; Murray K; Sim M; Connolly E; Blekkenhorst LC; Bondonno CP; Lewis JR; Gislason GH; Tjønneland A; Overvad K; Hodgson JM; Bondonno NP · Arteriosclerosis, thrombosis, and vascular biology · 2024
    Cohort study55,545 participantsCardiovascular Support Heart Health forVitamin K
  16. Association between vitamin K1 intake and mortality in the Danish Diet, Cancer, and Health cohort.
    Palmer CR; Bellinge JW; Dalgaard F; Sim M; Murray K; Connolly E; Blekkenhorst LC; Bondonno CP; Croft KD; Gislason G; Tjønneland A; Overvad K; Schultz C; Lewis JR; Hodgson JM; Bondonno NP · European journal of epidemiology · 2021
    Cohort study56,048 participantsCardiovascular Support Heart Health forVitamin K
  17. Dietary vitamin K intake associates with reduced all-cause mortality in non-alcoholic fatty liver disease patients.
    Huang Y; Zhu X; Han L; Hu H · Scientific reports · 2025
    Cohort study7,857 participantsGeneral Health forVitamin K
  18. The Effect of Topical Vitamin K1 on the Treatment of Cetuximab-Induced Skin Rashes in Metastatic Colorectal Cancer Patients.
    Roayaei M; Rezaei M; Najafizade N · Advanced biomedical research · 2024
    Randomized trial49 participantsGeneral Health forVitamin K
  19. Effect of vitamin K on improving post‑kidney transplant outcomes: a meta‑analysis.
    Sun Z; Zhu K; Liang G; Yan F; Chao S; Jia L; Niu Y · Experimental and therapeutic medicine · 2023
    Meta-analysis7 studies pooledGeneral Health forVitamin K
  20. Vitamin K1 intake is associated with lower risk for all-cause and cardiovascular disease mortality in community-dwelling older Australian women.
    Dupuy M; Radavelli-Bagatini S; Zhong L; Dalla Via J; Zhu K; Blekkenhorst LC; Bondonno NP; Linneberg A; Bellinge JW; Schultz C; Courtney W; Prince RL; Hodgson JM; Lewis JR; Sim M · Nutrition, metabolism, and cardiovascular diseases : NMCD · 2024
    Cohort study1,436 participantsGeneral Health forVitamin K
  21. The effect of vitamin K1 on arterial calcification activity in subjects with diabetes mellitus: a post hoc analysis of a double-blind, randomized, placebo-controlled trial.
    Bellinge JW; Francis RJ; Lee SC; Bondonno NP; Sim M; Lewis JR; Watts GF; Schultz CJ · The American journal of clinical nutrition · 2022
    Randomized trial149 participantsHeart Health forVitamin K