Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.
- The Effect of Short-Term Rhodiola rosea Supplementation on Simulated Game Time, Perceived Fatigue, and Performance in Basketball Players.
Wang J; Zhao H; Yu L; Zhao K; Jiang W; Liu S; Dai J; Xu L; Sun P; Yun H; Liu C · Nutrients · 2025
Randomized trial48 participantsflagEnergy forscienceRhodiola
- The Impact of Rhodiola Rosea Extract on Strength Performance in Alternative Bench-Press and Bench-Pull Exercises Under Resting and Mental Fatigue Conditions: A Randomized, Triple-Blinded, Placebo-Controlled, Crossover Trial.
Marcos-Frutos D; Leban Ž; Li Z; Zhang X; Lara PM; Alix-Fages C; Jiménez-Martínez P; Zebboudji N; Caillet A; Redondo B; Vera J; Janicijevic D; García-Ramos A · Nutrients · 2025
Randomized trial18 participantsflagEnergy forscienceRhodiola
- Scientific Opinion on the substantiation of a health claim related to Rhodiola rosea L. extract and reduction of mental fatigue pursuant to Article 13(5) of Regulation (EC) No 1924/2006.
EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) · EFSA journal. European Food Safety Authority · 2026
Guideline / consensusflagEnergy flagStress Relief forscienceRhodiola
- Rhodiola rosea for mental and physical fatigue in nursing students: a randomized controlled trial.
Punja S; Shamseer L; Olson K; Vohra S · PloS one · 2015
Randomized trial48 participantsflagEnergy forscienceRhodiola
- The Effectiveness of Rhodiola rosea L. Preparations in Alleviating Various Aspects of Life-Stress Symptoms and Stress-Induced Conditions-Encouraging Clinical Evidence.
Ivanova Stojcheva E; Quintela JC · Molecules (Basel, Switzerland) · 2022
Narrative reviewflagStress Relief flagProductivity Boost forscienceRhodiola
- [Effects of rhodiola rosea on oxidative stress and negative emotional states in patients with obstructive sleep apnea].
Yu HL; Zhang PP; Zhang C; Zhang X; Li ZZ; Li WQ; Fu AS · Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2019
Randomized trial90 participantsflagStress Relief forscienceRhodiola
- The effectiveness and efficacy of Rhodiola rosea L.: a systematic review of randomized clinical trials.
Hung SK; Perry R; Ernst E · Phytomedicine : international journal of phytotherapy and phytopharmacology · 2012
Systematic review11 studies pooledflagMental Focus forscienceRhodiola
- Acute Rhodiola rosea intake can improve endurance exercise performance.
De Bock K; Eijnde BO; Ramaekers M; Hespel P · International journal of sport nutrition and exercise metabolism · 2004
Randomized trial24 participantsflagMental Focus forscienceRhodiola
- Rosenroot (Rhodiola rosea): traditional use, chemical composition, pharmacology and clinical efficacy.
Panossian A; Wikman G; Sarris J · Phytomedicine : international journal of phytotherapy and phytopharmacology · 2010
Narrative reviewflagMental Focus flagBrain Health forscienceRhodiola
- Dose-Response Effects of Short-Term Rhodiola rosea (Golden Root Extract) Supplementation on Anaerobic Exercise Performance and Cognitive Function in Resistance-Trained Athletes: A Randomized, Crossover, Double-Blind, and Placebo-Controlled Study.
Koozehchian MS; Newton AT; Mabrey G; Bonness FM; Rafajlovska R; Naderi A · Nutrients · 2025
Randomized trial27 participantsflagBrain Health flagMental Focus forscienceRhodiola
- A combination of green tea, rhodiola, magnesium and B vitamins modulates brain activity and protects against the effects of induced social stress in healthy volunteers.
Boyle NB; Billington J; Lawton C; Quadt F; Dye L · Nutritional neuroscience · 2022
Randomized trial100 participantsflagBrain Health forscienceRhodiola
- Rhodiola rosea in stress induced fatigue--a double blind cross-over study of a standardized extract SHR-5 with a repeated low-dose regimen on the mental performance of healthy physicians during night duty.
Darbinyan V; Kteyan A; Panossian A; Gabrielian E; Wikman G; Wagner H · Phytomedicine : international journal of phytotherapy and phytopharmacology · 2001
Randomized trial56 participantsflagBrain Health flagProductivity Boost forscienceRhodiola
- Effects of a Rhodiola rosea extract on mental resource allocation and attention: An event-related potential dual task study.
Koop T; Dienel A; Heldmann M; Münte TF · Phytotherapy research : PTR · 2021
Single-arm trial50 participantsflagBrain Health flagCognitive Support forscienceRhodiola
- Evidence-based efficacy of adaptogens in fatigue, and molecular mechanisms related to their stress-protective activity.
Panossian A; Wikman G · Current clinical pharmacology · 2009
Narrative reviewflagCognitive Support flagMental Focus forscienceRhodiola
- Central additive effect of Ginkgo biloba and Rhodiola rosea on psychomotor vigilance task and short-term working memory accuracy.
Al-Kuraishy HM · Journal of intercultural ethnopharmacology · 2016
Clinical trial112 participantsflagCognitive Support forscienceRhodiola
- Clinical evidence for the adaptogenic effects of Withania somnifera and Rhodiola rosea - A systematic review with molecular interpretation of psychometric outcomes.
Łuszczak J; Kocki J · Annals of agricultural and environmental medicine : AAEM · 2026
Systematic review19 studies pooledflagCognitive Support flagStress Relief forscienceRhodiola
- A randomised, double-blind, placebo-controlled, parallel-group study of the standardised extract shr-5 of the roots of Rhodiola rosea in the treatment of subjects with stress-related fatigue.
Olsson EM; von Schéele B; Panossian AG · Planta medica · 2009
Randomized trial60 participantsflagCognitive Support flagProductivity Boost forscienceRhodiola
- Effects of fungal supplementation on endurance, immune function, and hematological profiles in adult athletes: a systematic review and meta-analysis
Meng-Yuan Shu, Xiu-Chang Zhang, Li Zuo, Fang-Lin Jiang, Jian Liang, Fang Li · Frontiers in Nutrition · 2025
Meta-analysis34 participants2 studies pooledflagEnergy forscienceCordyceps
- Effect of Cs-4 (Cordyceps sinensis) on exercise performance in healthy older subjects: a double-blind, placebo-controlled trial
Steve Chen, Zhaoping Li, Robert Krochmal, Marlon Abrazado, Woosong Kim, Christopher B Cooper · Journal of Alternative and Complementary Medicine · 2010
Randomized trialflagEnergy forscienceCordyceps
- Effects of Rhodiola rosea on Physical and Decision-Making Performance in Football Players: A Randomised Controlled Trial.
Dou Y; Wang Y; Zhang W; Jiang Y; Zhang J; Yang T; Han Z; Li Y; Liu C; Ren D · Nutrients · 2026
Randomized trial24 participantsflagEnergy flagMental Focus forscienceRhodiola
- Combined Effects of Rhodiola Rosea and Caffeine Supplementation on Straight Punch Explosive Power in Untrained and Trained Boxing Volunteers: A Synergistic Approach.
Tao B; Sun H; Li H; Xu Z; Xu Y; Chen L; Ma C; Zhang X; Yu L; Bao S; Liu C · Metabolites · 2025
Randomized trial96 participantsflagEnergy forscienceRhodiola
- Rhodiola rosea in Subjects with Prolonged or Chronic Fatigue Symptoms: Results of an Open-Label Clinical Trial.
Lekomtseva Y; Zhukova I; Wacker A · Complementary medicine research · 2019
Single-arm trial100 participantsflagEnergy flagStress Relief forscienceRhodiola
- Combined Rhodiola rosea and eccentric training boost endurance performance and lower-limb reactive strength in recreationally active women.
Wang IL; Su Y; Zhang L; Tang M; Chen YM · Frontiers in physiology · 2025
Randomized trial30 participantsflagEnergy forscienceRhodiola
- Effects of Rhodiola rosea supplementation on mental performance, physical capacity, and oxidative stress biomarkers in healthy men.
Jówko E; Sadowski J; Długołęcka B; Gierczuk D; Opaszowski B; Cieśliński I · Journal of sport and health science · 2022
Randomized trial26 participantsflagMental Focus flagProductivity Boost forscienceRhodiola
- Vitamin B-6 supplementation in elderly men: effects on mood, memory, performance and mental effort.
Deijen JB; van der Beek EJ; Orlebeke JF; van den Berg H · Psychopharmacology · 1995
Randomized trial76 participantsflagMental Focus forscienceVitamin B6
- The effect of vitamin B6 on cognition.
Malouf R; Grimley Evans J · The Cochrane database of systematic reviews · 2004
Systematic review109 participants2 studies pooledflagMental Focus forscienceVitamin B6
- Antiemetic use during pregnancy and child neurodevelopment: population-based birth cohort study.
Cho Y; Choi EY; Han JY; Kim H; Choe YJ; Shin JY · BMC medicine · 2025
Cohort study630,904 participantsflagMental Focus forscienceVitamin B6
- A nutritional blend of taurine, vitamins B6, B9, and B12 improves motivated behaviors in healthy adults-a double-blinded randomized clinical trial.
Anlacan VM; Jamora RDG; Krattinger LF; De Longis E; Hartweg M; Steinmann M; Trovò L · Frontiers in nutrition · 2026
Randomized trial44 participantsflagMental Focus forscienceVitamin B6
- B-Vitamin Therapy for Kidney Transplant Recipients Lowers Homocysteine and Improves Selective Cognitive Outcomes in the Randomized FAVORIT Ancillary Cognitive Trial
Tammy M Scott, Graham Rogers, Daniel E Weiner, Kathryn Livingston, Jacob Selhub, Paul F Jacques, Irwin H Rosenberg, Aron M Troen · The Journal of Prevention of Alzheimer's Disease · 2017
Randomized trial584 participantsflagMental Focus forscienceVitamin B6
- Efficacy of Pharmacological Interventions in Milder Depression: A Systematic Review and Meta-Analysis.
Urata M; Sakurai H; Ueno F; Maruki T; Tada T; Uchida T; Matsumoto Y; Murao M; Tomita M; Baba H; Kato M; Tsuboi T; Watanabe K · Neuropsychopharmacology reports · 2025
Meta-analysis1,049 participants2 studies pooledflagMood Support forscienceRhodiola
- The Effect of Acute Rhodiola rosea Ingestion on Exercise Heart Rate, Substrate Utilisation, Mood State, and Perceptions of Exertion, Arousal, and Pleasure/Displeasure in Active Men.
Duncan MJ; Clarke ND · Journal of sports medicine (Hindawi Publishing Corporation) · 2015
Clinical trial10 participantsflagMood Support forscienceRhodiola
- Herbal medicine for depression, anxiety and insomnia: a review of psychopharmacology and clinical evidence.
Sarris J; Panossian A; Schweitzer I; Stough C; Scholey A · European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology · 2012
Systematic review66 studies pooledflagMood Support forscienceRhodiola
- Medicinal Plants in the Treatment of Depression. II: Evidence from Clinical Trials.
Moragrega I; Ríos JL · Planta medica · 2022
Systematic reviewflagMood Support forscienceRhodiola
- Multicenter, open-label, exploratory clinical trial with Rhodiola rosea extract in patients suffering from burnout symptoms.
Kasper S; Dienel A · Neuropsychiatric disease and treatment · 2020
Single-arm trial118 participantsflagMood Support forscienceRhodiola
- Acute Cordyceps militaris supplementation and elevated resting oxygen uptake with faster reaction times: A randomized crossover trial
Hamidreza Farzan, Maryam Koushkie Jahromi · PLOS ONE · 2026
Randomized trial12 participantsflagProductivity Boost forscienceCordyceps
- A double-blind, placebo-controlled pilot study of the stimulating and adaptogenic effect of Rhodiola rosea SHR-5 extract on the fatigue of students caused by stress during an examination period with a repeated low-dose regimen.
Spasov AA; Wikman GK; Mandrikov VB; Mironova IA; Neumoin VV · Phytomedicine : international journal of phytotherapy and phytopharmacology · 2000
Randomized trialflagProductivity Boost forscienceRhodiola
- Stress management and the role of Rhodiola rosea: a review.
Anghelescu IG; Edwards D; Seifritz E; Kasper S · International journal of psychiatry in clinical practice · 2019
Narrative reviewflagStress Relief forscienceRhodiola
- Plant-based medicines for anxiety disorders, part 2: a review of clinical studies with supporting preclinical evidence.
Sarris J; McIntyre E; Camfield DA · CNS drugs · 2013
Narrative reviewflagStress Relief forscienceRhodiola
- Effect of magnesium and vitamin B6 supplementation on mental health and quality of life in stressed healthy adults: Post-hoc analysis of a randomised controlled trial.
Noah L; Dye L; Bois De Fer B; Mazur A; Pickering G; Pouteau E · Stress and health : journal of the International Society for the Investigation of Stress · 2021
Randomized trialflagStress Relief forscienceVitamin B6
- Can Vitamin B6 Help to Prevent Postpartum Depression? A Randomized Controlled Trial.
Khodadad M; Bahadoran P; Kheirabadi GR; Sabzghabaee AM · International journal of preventive medicine · 2022
Randomized trial81 participantsflagStress Relief forscienceVitamin B6
- RENAL PROTECTIVE EFFECT AND CLINICAL ANALYSIS OF VITAMIN B 6 IN PATIENTS WITH SEPSIS.
Wang Y; Lu WL; Feng WM; Xu W; Liu LH; He LM · Shock (Augusta, Ga.) · 2024
Randomized trial128 participantsflagStress Relief forscienceVitamin B6
- Superiority of magnesium and vitamin B6 over magnesium alone on severe stress in healthy adults with low magnesemia: A randomized, single-blind clinical trial.
Pouteau E; Kabir-Ahmadi M; Noah L; Mazur A; Dye L; Hellhammer J; Pickering G; Dubray C · PloS one · 2019
Randomized trial264 participantsflagStress Relief forscienceVitamin B6
- Associations between dietary intake of B-vitamins and psychological disorders among Iranian women: a cross-sectional study.
Mozaffari H; Darooghegi Mofrad M; Surkan PJ; Askari M; Azadbakht L · Public health nutrition · 2021
Cross-sectional study447 participantsflagStress Relief forscienceVitamin B6