Liver Guard

Liver Guard

Source Naturals4.5 (597 ratings)
Format:Tablet Quantity: 120 Tablet(s) · 60 servings
Goals
$28.67 $0.47 per serving

Product analysis

47 out of 100

Liver Guard provides B vitamins and vitamin C that support normal energy use when intake is low. Unspecified ingredient forms and mixed-source proportions make parts of the formula harder to compare.

AI assessment of the formula, label and price. How scoring works

Nutrient Quality32

Some nutrient and plant sources are identified, but many form-quality conclusions remain uncertain. Mixed-source proportions and unspecified botanical forms limit comparisons of the complete formula.

Ingredient Transparency68

All ingredient amounts and many forms are disclosed, helping compare the serving. Missing forms and mixed-source proportions still leave important details unclear.

Value For Money41

The cost comparison is mixed, with moderate value for riboflavin and CoQ10. Choline and niacin compare less favorably, while many other ingredient values remain uncertain.

Customer Satisfaction74

Customer feedback is positive across a moderate number of ratings. The feedback describes satisfaction and does not establish effectiveness.

Product Focus29

The formula combines many nutrients and plant ingredients, making it broad rather than focused. The clearest supported goal is normal energy-related nutrition when intake is inadequate.

Format
Tablet
Container
120 Tablet(s)
Per serving
$0.47
Customer rating
4.5 · 597 ratings
Report analysis

Goals

Impact
Moderate effect
C- Ingredient FitF PathwaysB EvidenceA+ Formulation Logic
Vitamin B5 · 15 mgMagnesium · 50 mgRiboflavin · 8 mgThiamin · 8 mgVitamin B12 · 50 mcgPotassium · 48 mgCoenzyme Q-10 · 12 mg
Study evidence
Magnesium Supportive 4 studies
Potassium Supportive 2 studies
Thiamin Disputed 12 studies

Ingredients

IngredientAmount per servingScore
Calories
5 Calorie(s)
Vitamin C (Ascorbic Acid, Ascorbyl Palmitate, Zinc Ascorbate)
250 mg
Vitamin E (D-Alpha-Tocopheryl Succinate)
67 mg
Thiamine
8 mg 37
Riboflavin
8 mg 48
Niacin
50 mg 65
Vitamin B6 (Pyridoxine Hydrochloride)
10 mg
Folate (Calcium Folinate, Folic Acid)
680 mcg DFE
Vitamin B12 (Cyanocobalamin)
50 mcg
Panthothenic Acid (Calcium D-Pantothenate)
15 mg
Calcium (Calcium D-Glucarate, Dicalcium Phosphate)
30 mg
Magnesium (Magnesium Amino Acid Complex, Magnesium Oxide)
50 mg
Zinc (OptiZinc, Zinc Ascorbate)
15 mg
Selenium (L-Selenomethionine)
50 mcg
Potassium (Potassium Citrate)
48 mg
N-Acetyl Cysteine
350 mg
Silymarin (Milk Thistle seed extract)
250 mg
Dandelion whole plant/root extract
175 mg
Turmeric rhizome extract
150 mg 12
Alpha-Lipoic Acid
150 mg
Bupleurum root extract
100 mg
Gamma-Vitamin E Complex
100 mg
Calcium D-Glucarate
100 mg
Oregon Grape
75 mg
Artichoke aerial parts extract (Cynarins)
75 mg
Choline (Choline Bitartrate)
50 mg 55
Inositol
50 mg
Coenzyme Q10
12 mg 40
Adults 18–50
Report overview
Niacin · 50 mg OverallScore65
A- Active Ingredient Quality & BioavailabilityC+ Dose, Safety & Label TransparencyF Value
The serving provides 50 mg of niacin as niacinamide at a high cost. The amount is below the range described for niacinamide in general use. Niacinamide is a non-flushing form.
How this ingredient is rated

Active Ingredient Quality & Bioavailability86

Niacinamide is a standard form of vitamin B3 for general use.
Niacin Form & Goal Alignment
Niacinamide is a standard form of vitamin B3 for general use.
Precursor Source Quality
Niacinamide is a standard B3 form, and no advanced NAD+ claim is recorded.

Dose, Safety & Label Transparency67

The label identifies niacinamide and lists 50 mg per serving. It is a non-flushing form.
Clarity of Chemical Form
The niacin source form is named as niacinamide.
Form-Specific Dosage Efficacy
The 50 mg serving is below the range described for niacinamide in general use.
Flush Risk & Safety Labeling
Niacinamide is non-flushing; no no-flush claim is recorded.

Value20

The cost per serving is high for the niacin provided.
Price Per Effective Serving
The cost per serving is high for the niacin provided.
C+ Active Ingredient Quality & BioavailabilityC- Dose, Safety & Label TransparencyF Value
Each serving supplies 50 mg of choline from Choline Bitartrate, but the cost relative to the amount of choline is high. It includes flow agents.
How this ingredient is rated

Active Ingredient Quality & Bioavailability68

The source is Choline Bitartrate, a systemic choline form. It includes flow agents.
Choline Form Efficacy & Bioavailability
Choline Bitartrate is a systemic choline form.
Formula Purity & Excipient Quality
It includes flow agents.

Dose, Safety & Label Transparency59

The label declares both the 50 mg choline amount per serving and its source.
Choline Dose by Declared Basis
Each serving provides 50 mg of choline.
Elemental Yield Transparency
The label states both the choline amount and its source.

Value20

The cost relative to the choline supplied is high.
Price per 100 mg of Declared Choline Basis
The cost relative to the choline supplied is high.
Riboflavin · 8 mg OverallScore48
F Active Ingredient Quality & BioavailabilityC Dose, Safety & Label TransparencyD+ Value
A serving supplies 8 mg of riboflavin, a low amount, at a fairly high cost per serving. It uses standard riboflavin, which requires conversion in the liver. The Other Ingredients panel lists no artificial colors, flavors or synthetic sweeteners.
How this ingredient is rated

Active Ingredient Quality & Bioavailability30

It uses standard riboflavin, which needs conversion in the liver before it participates in energy metabolism.
Riboflavin Form Quality
It uses standard riboflavin, which needs conversion in the liver before it participates in energy metabolism.

Dose, Safety & Label Transparency64

A serving supplies 8 mg of riboflavin, a low amount. The Other Ingredients panel lists no artificial colors, flavors or synthetic sweeteners.
Dosage for Energy & Metabolism
A serving supplies 8 mg of riboflavin, a low amount.
R5P Elemental Yield Transparency
The phosphate yield question does not apply to standard riboflavin.
Additive Purity
The Other Ingredients panel lists no artificial colors, flavors or synthetic sweeteners.

Value50

The cost per serving is fairly high.
Price per Serving Value
The cost per serving is fairly high.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Effects of Coenzyme Q10 on Statin-Induced Myopathy: An Updated Meta-Analysis of Randomized Controlled Trials.
    Qu H; Guo M; Chai H; Wang WT; Gao ZY; Shi DZ · Journal of the American Heart Association · 2019
    Meta-analysis575 participants12 studies pooledEnergy forCoenzyme Q-10
  2. Coenzyme Q10 Supplementation in Athletes: A Systematic Review.
    Fernandes MSS; Fidelis DEDS; Aidar FJ; Badicu G; Greco G; Cataldi S; Santos GCJ; de Souza RF; Ardigò LP · Nutrients · 2026
    Systematic review16 studies pooledEnergy forCoenzyme Q-10
  3. Effectiveness of Coenzyme Q10 Supplementation for Reducing Fatigue: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
    Tsai IC; Hsu CW; Chang CH; Tseng PT; Chang KV · Frontiers in pharmacology · 2024
    Meta-analysis1,126 participants13 studies pooledEnergy forCoenzyme Q-10
  4. Antifatigue effects of coenzyme Q10 during physical fatigue.
    Mizuno K; Tanaka M; Nozaki S; Mizuma H; Ataka S; Tahara T; Sugino T; Shirai T; Kajimoto Y; Kuratsune H; Kajimoto O; Watanabe Y · Nutrition (Burbank, Los Angeles County, Calif.) · 2008
    Randomized trial17 participantsEnergy forCoenzyme Q-10
  5. Effect of coenzyme Q10 supplementation on fatigue: A systematic review of interventional studies.
    Mehrabani S; Askari G; Miraghajani M; Tavakoly R; Arab A · Complementary therapies in medicine · 2019
    Systematic review16 studies pooledEnergy forCoenzyme Q-10
  6. Magnesium-L-threonate improves sleep quality and daytime functioning in adults with self-reported sleep problems: A randomized controlled trial.
    Hausenblas HA; Lynch T; Hooper S; Shrestha A; Rosendale D; Gu J · Sleep medicine: X · 2025
    Randomized trial80 participantsEnergy forMagnesium
  7. Total magnesium intake and risk of frailty in older women.
    Struijk EA; Fung TT; Bischoff-Ferrari HA; Willett WC; Lopez-Garcia E · Journal of cachexia, sarcopenia and muscle · 2024
    Cohort study81,524 participantsEnergy forMagnesium
  8. Red blood cell magnesium and chronic fatigue syndrome.
    Cox IM; Campbell MJ; Dowson D · Lancet (London, England) · 1991
    Randomized trial32 participantsEnergy forMagnesium
  9. Exercise, magnesium and immune function.
    Laires MJ; Monteiro C · Magnesium research · 2008
    Narrative reviewEnergy forMagnesium
  10. [Efficacy of potassium N-acetylaminosuccinate (Cogitum) in the treatment of asthenic syndrome: results of double-blind placebo-controlled trial].
    Esin RG; Khayrullin IK; Esin OR; Fatykhova AF; Gismatullina EI; Isaeva YN · Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova · 2023
    Randomized trial37 participantsEnergy forPotassium
  11. Human resting energy expenditure in relation to dietary potassium.
    Dériaz O; Thériault G; Lavallée N; Fournier G; Nadeau A; Bouchard C · The American journal of clinical nutrition · 1991
    Randomized trial8 participantsEnergy forPotassium
  12. Physicochemical properties of and volatile compounds in riboflavin fortified cloudy apple juice; study of its effect on job fatigue among Egyptian construction workers.
    Fouad S; Ibrahim GE; Hussein AMS; Ibrahim FA; El Gendy A · Heliyon · 2021
    Non-randomized trialEnergy forRiboflavin
  13. Vitamin B status in patients with chronic fatigue syndrome.
    Heap LC; Peters TJ; Wessely S · Journal of the Royal Society of Medicine · 1999
    Case-control study30 participantsEnergy forRiboflavin
  14. B-vitamins, related vitamers, and metabolites in patients with quiescent inflammatory bowel disease and chronic fatigue treated with high dose oral thiamine.
    Bager P; Hvas CL; Hansen MM; Ueland P; Dahlerup JF · Molecular medicine (Cambridge, Mass.) · 2023
    Observational studyEnergy forRiboflavin
  15. Metabolic features of chronic fatigue syndrome.
    Naviaux RK; Naviaux JC; Li K; Bright AT; Alaynick WA; Wang L; Baxter A; Nathan N; Anderson W; Gordon E · Proceedings of the National Academy of Sciences of the United States of America · 2024
    Case-control study84 participantsEnergy forRiboflavin
  16. Effectiveness of Riboflavin in Inherited Metabolic Diseases: A Systematic Review
    Bregje Jaeger, Nina N Stolwijk, Femke Aaldering, Charlotte A Ruys, Marije Smits, Nicole I Wolf, Carla E M Hollak, Annet M Bosch · Journal of Inherited Metabolic Disease · 2026
    Systematic review381 studies pooledEnergy forRiboflavin
  17. Influence of thiamin supplementation on the health and general well-being of an elderly Irish population with marginal thiamin deficiency.
    Smidt LJ; Cremin FM; Grivetti LE; Clifford AJ · Journal of gerontology · 1991
    Randomized trial80 participantsEnergy forThiamin
  18. Randomised clinical trial: high-dose oral thiamine versus placebo for chronic fatigue in patients with quiescent inflammatory bowel disease.
    Bager P; Hvas CL; Rud CL; Dahlerup JF · Alimentary pharmacology & therapeutics · 2021
    Randomized trial40 participantsEnergy forThiamin
  19. Dietary reference values for thiamin.
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA); Turck D; Bresson JL; Burlingame B; Dean T; Fairweather-Tait S; Heinonen M; Hirsch-Ernst KI; Mangelsdorf I; McArdle HJ; Naska A; Nowicka G; Pentieva K; Sanz Y; Siani A; Sjödin A; Stern M; Tomé D; Van Loveren H; Vinceti M; Willatts P; Lamberg-Allardt C; Przyrembel H; Tetens I; Gudelj Rakic J; Ioannidou S; de Sesmaisons-Lecarré A; Forss AC; Neuhäuser-Berthold M · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusEnergy forThiamin
  20. Effects of thiamine supplementation on exercise-induced fatigue.
    Suzuki M; Itokawa Y · Metabolic brain disease · 1996
    Randomized trial16 participantsEnergy forThiamin