Life Extension Mix Tablets without Copper

Life Extension Mix Tablets without Copper

Life Extension4.7 (148 ratings)
Format:Tablet Quantity: 240 Tablet(s) · 30 servings
Goals
$55.45 $1.84 per serving

Product analysis

44 out of 100

Life Extension Mix Tablets without Copper offers broad nutritional support for normal energy use, immunity and bone maintenance when intake is low. Missing blend proportions and unnamed components make its many extras harder to compare.

AI assessment of the formula, label and price. How scoring works

Nutrient Quality41

Some nutrients use favorable forms, particularly iodine and zinc. Unknown mineral proportions and incomplete form details limit a clear judgment of the full mixture.

Ingredient Transparency71

Amounts and many ingredient forms are stated, helping identify much of the formula. Unnamed blend components and missing mixture proportions prevent precise comparison.

Value For Money33

The formula is relatively costly for many of its individual nutrients. Vitamin B6 offers better value within the mix, while several other contributions remain uncertain.

Customer Satisfaction73

Customer feedback is very positive, though based on a relatively modest number of ratings. That gives some context on satisfaction without establishing the formula’s many health claims.

Product Focus0

The extensive formula spreads across many aims, making its practical purpose broad. Filling nutrient gaps has a clearer basis than expecting added benefits across every advertised area.

Format
Tablet
Container
240 Tablet(s)
Per serving
$1.84
Customer rating
4.7 · 148 ratings
Report analysis

Goals

Heart Health
Impact
High effect
D+ Ingredient FitA+ PathwaysA EvidenceA+ Formulation Logic
Magnesium · 420 mgVitamin B12 · 600 mcgVitamin B6 · 105 mgTaurine · 200 mgGreen Tea · 325 mgFolate · 400 mcg DFEVitamin D · 50 mcg

Magnesium offers limited, inconsistent blood-pressure support, while the B vitamins participate in homocysteine metabolism without established general cardiac prevention benefit. Green-tea findings depend on the specific preparation, so this extract cannot inherit effects from a different catechin preparation. Thiamin and selenium matter when intake is deficient, with no established cardiovascular benefit when intake is adequate. The small taurine and potassium amounts provide limited support for blood-pressure expectations.

How this product is rated for Heart Health

Ingredient fit52

Heart-related ingredients sit within a broader formula with other active ingredients. The relevant declared amounts provide substantial but incomplete coverage of the saved exposure comparison.
Goal fit
Heart-related ingredients sit within a broader formula with other active ingredients.
Dose adequacy
The relevant declared amounts provide substantial but incomplete coverage of the saved exposure comparison.

Pathways100

The strongest saved connection is to homocysteine metabolism. Coverage across other heart-related roles is broader.
Depth
The strongest saved connection is to homocysteine metabolism.
Breadth
The broader saved findings cover blood-vessel function, blood-pressure and vascular-tone support, homocysteine metabolism. .

Evidence92

Green Tea leads the saved evidence finding. Accepted preparation matches do not remove the ingredient-specific limitations described above.
Evidence strength
Green Tea provides the leading evidence contribution in the saved comparison; its clinical limitations still apply.
Studied preparation
The saved finding accepts the preparations used for its included ingredients; it does not establish that every labelled preparation matches a clinical trial.

Formulation logic98

The saved checks find no missing required partner or configured conflict. Some included amounts fall below the comparison screen.
Partner coverage
The included ingredients do not lack a required partner under the saved finding; this does not establish added benefit from combining them.
Conflicts
No configured ingredient conflict was triggered by the supplied facts.
Effective doses
Most included ingredients meet the saved amount screen; Quercetin falls below it.
Study evidence
Folate Supportive 116 studies
Green Tea Supportive 84 studies
Magnesium Supportive 158 studies
Niacin Supportive 105 studies
Potassium Supportive 182 studies
Selenium Mixed 89 studies
Taurine Supportive 25 studies
Vitamin B6 Supportive 44 studies
Vitamin D Mixed 164 studies
Impact
Highest effect
C- Ingredient FitA+ PathwaysA+ EvidenceA+ Formulation Logic
Folate · 400 mcg DFEVitamin B12 · 600 mcgVitamin B6 · 105 mgMolybdenum · 125 mcgSelenium · 200 mcgMagnesium · 420 mgVitamin E · 60 mgZinc · 35 mgVitamin C · 970 mgTaurine · 200 mgRiboflavin · 50 mg

Folate supports methyl-group metabolism; low folate can impair elimination of arsenic in exposed adults, but the supplied findings do not establish routine toxin removal in adequately nourished people. Selenium has limited mercury-related findings in low-selenium or exposed groups. NAC’s glutathione-precursor role does not establish general toxin clearance from routine supplementation.

How this product is rated for Liver & Detox

Ingredient fit57

The formula includes nutrients counted for this goal alongside many ingredients serving broader purposes. Serving amounts provide differing matches to the supplied reference amounts; these comparisons do not identify proven routine toxin-clearance doses.
Goal fit
The formula includes nutrients counted for this goal alongside many ingredients serving broader purposes.
Dose adequacy
Serving amounts provide differing matches to the supplied reference amounts; these comparisons do not identify proven routine toxin-clearance doses.

Pathways100

The strongest represented area is glutathione and conjugation, reflecting ingredient roles rather than demonstrated toxin clearance.
Depth
The strongest represented area is glutathione and conjugation, reflecting ingredient roles rather than demonstrated toxin clearance.
Breadth
The represented coverage includes liver cell integrity and fat export, glutathione and conjugation, methyl-group supply, detox-enzyme induction. This does not establish removal of unspecified toxins.

Evidence98

Vitamin B9 (Folate) leads the saved evidence comparison; the supplied findings remain limited to their nutritional or disease-specific contexts.
Evidence strength
Vitamin B9 (Folate) leads the saved evidence comparison; the supplied findings remain limited to their nutritional or disease-specific contexts.
Studied preparation
Preparation matching is incomplete for Molybdenum, Vitamin B2 (Riboflavin), Vitamin B6.

Formulation logic100

The counted ingredients meet the saved minimum amount check, which is not evidence of a clinically effective routine detoxification dose.
Partner coverage
No required partner is missing among the counted ingredients; this does not establish added detoxification benefit from their combination.
Conflicts
No configured ingredient conflict was identified from the supplied facts.
Effective doses
The counted ingredients meet the saved minimum amount check, which is not evidence of a clinically effective routine detoxification dose.
Study evidence
Folate Supportive 16 studies
Green Tea Disputed 16 studies
Magnesium Supportive 19 studies
Selenium Supportive 10 studies
Taurine Supportive 2 studies
Vitamin C Supportive 9 studies
Vitamin E Supportive 23 studies
Zinc Supportive 30 studies
Impact
Highest effect
C+ Ingredient FitA+ PathwaysA- EvidenceA Formulation Logic
Folate · 400 mcg DFEVitamin B12 · 600 mcgVitamin D · 50 mcgMagnesium · 420 mgBoron · 3 mgSelenium · 200 mcgTaurine · 200 mgAshwagandha · 125 mgZinc · 35 mgVitamin C · 970 mg

B vitamins contribute to normal energy metabolism, while folate and B12 support normal blood formation. Magnesium can help fill a dietary gap and supports normal energy and mineral metabolism. Vitamin D contributes to bone and mineral nutrition when intake is inadequate. These nutritional roles do not establish extra health benefits when intake is already adequate.

How this product is rated for Everyday Health

Ingredient fit68

The recognized nutritional ingredients share the formula with actives serving other purposes, so its focus on routine general health is mixed. The recognized amounts cover part of the saved comparison ranges; these ranges do not define personal requirements or a clinical response.
Goal fit
The recognized nutritional ingredients share the formula with actives serving other purposes, so its focus on routine general health is mixed.
Dose adequacy
The recognized amounts cover part of the saved comparison ranges; these ranges do not define personal requirements or a clinical response.

Pathways100

The strongest saved connection is normal energy metabolism; this describes ingredient roles rather than demonstrated improvement in overall health.
Depth
The strongest saved connection is normal energy metabolism; this describes ingredient roles rather than demonstrated improvement in overall health.
Breadth
4 evaluated areas reach the saved coverage threshold, led by normal energy metabolism.

Evidence86

Magnesium leads the saved evidence finding; its nutritional contribution is conditional on inadequate intake.
Evidence strength
Magnesium leads the saved evidence finding; its nutritional contribution is conditional on inadequate intake.
Studied preparation
The saved finding accepts the evaluated preparations; it does not establish superiority of a particular chemical form or delivery method.

Formulation logic93

The formula triggers the configured high-B6 concern because its serving contains at least 100 mg of vitamin B6.
Partner coverage
No recognized ingredient has an unmet partner requirement; an additional benefit from combining the ingredients is not established.
Conflicts
The formula triggers the configured high-B6 concern because its serving contains at least 100 mg of vitamin B6.
Effective doses
The recognized ingredients reach the saved amount threshold; this does not establish improved health outcomes.
Study evidence
Boron Supportive 6 studies
Bromelain Supportive 11 studies
Folate Supportive 80 studies
Magnesium Supportive 114 studies
Selenium Supportive 70 studies
Taurine No effect 3 studies
Vitamin C Supportive 56 studies
Vitamin D Supportive 115 studies
Zinc Supportive 60 studies
Impact
High effect
D+ Ingredient FitB+ PathwaysA+ EvidenceA+ Formulation Logic
Vitamin D · 50 mcgVitamin E · 60 mgTaurine · 200 mgVitamin C · 970 mgGreen Tea · 325 mg

Magnesium and zinc can help address low intake that contributes to low-grade inflammation; added benefit is not established when intake is adequate. Vitamin C has a limited connection to lower CRP in people with elevated baseline inflammation. Other antioxidant nutrients contribute to normal defenses, but their presence does not establish broad inflammation relief. The supplied findings emphasize oxidative stress, with more limited relevance to other inflammatory processes.

How this product is rated for Inflammation

Ingredient fit52

The formula contains relevant ingredients, with focus and amount findings reflecting its broader composition.
Goal fit
Relevant ingredients are present within a broader formula containing ingredients aimed at other needs.
Dose adequacy
The counted ingredients meet the saved amount references to differing extents.

Pathways80

The saved findings span oxidative stress and inflammatory gene signalling. They do not establish broad clinical inflammation relief.
Depth
The strongest saved connection is oxidative and mitochondrial stress.
Breadth
The saved findings cover oxidative stress and inflammatory gene signalling, with limited reach into the other pathways.

Evidence96

The saved evidence findings reflect ingredient and preparation matches. Human findings remain limited by population, outcome or preparation differences.
Evidence strength
Vitamin E provides the strongest saved evidence finding among the counted ingredients, while its specific human-evidence limitations still apply.
Studied preparation
The counted preparations match the saved preparation criteria; this does not remove the limitations of the underlying human findings.

Formulation logic100

The counted ingredients meet the saved minimum amounts and most partner requirements, with no matched conflict recorded.
Partner coverage
The counted ingredients can contribute alone or meet the saved partner requirements.
Conflicts
No matched conflict was recorded in the supplied calculation.
Effective doses
All counted ingredients reach the saved minimum amount threshold; this threshold is not proof of an effective clinical dose.
Study evidence
Apigenin No effect 1 study
Bromelain Supportive 12 studies
Luteolin Not classified

No linked studies yet.

Lycopene Supportive 15 studies
Magnesium Supportive 41 studies
Selenium Supportive 34 studies
Taurine Supportive 12 studies
Vitamin C Supportive 50 studies
Vitamin D Supportive 101 studies
Vitamin E Supportive 20 studies
Zinc Supportive 64 studies
Impact
High effect
C Ingredient FitD- PathwaysA+ EvidenceA+ Formulation Logic
Biotin · 3000 mcgNiacin · 190 mg NEVitamin B12 · 600 mcgRiboflavin · 50 mgThiamin · 125 mgVitamin B5 · 600 mgVitamin B6 · 105 mgVitamin D · 50 mcgZinc · 35 mgMagnesium · 420 mgGreen Tea · 325 mg

Iodine supports thyroid hormone production when intake is deficient; additional iodine does not establish a faster metabolic rate when intake is adequate. Green tea catechin preparations have limited, mixed evidence for a small short-term rise in energy expenditure. Extract mass alone does not establish the studied catechin and caffeine exposure.

How this product is rated for Metabolism Support

Ingredient fit64

The saved findings count relevant ingredient amounts within a broader formula aimed at several needs.
Goal fit
The saved findings count relevant ingredient amounts within a broader formula aimed at several needs.
Dose adequacy
The declared serving amounts receive substantial consideration; this compares amounts with supplied reference ranges, without proving a metabolism-related effect.

Pathways42

The strongest saved connection is to adrenergic drive, based on the counted ingredients; this does not itself demonstrate increased energy expenditure. One metabolism-related-related area reaches the saved coverage threshold, leaving the other areas less represented.
Depth
The strongest saved connection is to adrenergic drive, based on the counted ingredients; this does not itself demonstrate increased energy expenditure.
Breadth
One metabolism-related-related area reaches the saved coverage threshold, leaving the other areas less represented.

Evidence100

Vitamin B1 (Thiamin) provides the strongest saved evidence contribution here; its population and outcome limitations still apply.
Evidence strength
Vitamin B1 (Thiamin) provides the strongest saved evidence contribution here; its population and outcome limitations still apply.
Studied preparation
The counted ingredients meet the saved preparation criteria; this does not make all labelled forms interchangeable with every clinical trial.

Formulation logic100

All counted ingredients meet the saved minimum amount criterion; this does not establish proven thermogenic doses.
Partner coverage
The counted ingredients require no missing partner under the supplied findings; this does not imply an added benefit from combining them.
Conflicts
No listed ingredient conflict was matched in the supplied findings; this does not establish medication compatibility.
Effective doses
All counted ingredients meet the saved minimum amount criterion; this does not establish proven thermogenic doses.
Study evidence
Biotin Supportive 5 studies
Chromium Supportive 47 studies
Green Tea Supportive 31 studies
Iodine Mixed 17 studies
Magnesium Supportive 61 studies
Niacin Supportive 17 studies
Selenium Mixed 28 studies
Taurine Supportive 11 studies
Thiamin Supportive 11 studies
Vitamin B6 Supportive 16 studies
Vitamin D Supportive 65 studies
Zinc Supportive 12 studies
Stress Relief
Impact
High effect
C- Ingredient FitA+ PathwaysA EvidenceA+ Formulation Logic
Vitamin D · 50 mcgAshwagandha · 125 mgMagnesium · 420 mgFolate · 400 mcg DFEVitamin B12 · 600 mcgVitamin B6 · 105 mgVitamin C · 970 mg

Sensoril ashwagandha offers a direct connection to perceived stress, while magnesium may help when magnesium intake is low or in selected clinical settings. Vitamin C has some stress-response findings, but nutritional status and formulation limit generalization. Vitamin B6 has some anxiety evidence, often alongside other ingredients; the wider nutrient mixture does not establish an added emotional stress benefit.

How this product is rated for Stress Relief

Ingredient fit58

Ashwagandha supplies the main practical connection to stress relief. The serving amounts are interpreted within the supplied guidance.
Goal fit
Ashwagandha supplies stress relevance within a formula containing ingredients aimed at other goals.
Dose adequacy
Ashwagandha has a known serving amount that contributes to the saved findings; the amount guidance does not prove an effective daily regimen.

Pathways100

The strongest finding concerns stress regulation, with sleep recovery also represented.
Depth
Stress-hormone regulation is the strongest saved finding, led by ashwagandha.
Breadth
The saved findings span stress regulation, calming, nutrient-related functions and sleep recovery. These links do not demonstrate combined clinical benefit.

Evidence95

Ashwagandha anchors the evidence, with the preparation, population and outcome limitations described for those ingredients.
Evidence strength
Ashwagandha leads the saved evidence finding; the supplied limitations still restrict how broadly its benefit can be described.
Studied preparation
The identified ashwagandha extract is accepted as a studied preparation in the saved findings.

Formulation logic100

The credited ingredients retain their individual contributions and no evaluated conflict was triggered. This does not establish synergy.
Partner coverage
The credited ingredients retain their individual contributions without requiring an additional missing partner.
Conflicts
No evaluated formulation conflict was triggered by the supplied facts.
Effective doses
All credited ingredients meet the saved amount threshold, which is an inclusion rule rather than a proven clinical effect.
Study evidence
Apigenin Supportive 2 studies
Folate Supportive 19 studies
Magnesium Supportive 13 studies
Taurine Supportive 5 studies
Vitamin C Supportive 11 studies
Vitamin D Supportive 41 studies
Zinc Supportive 9 studies

Ingredients

IngredientAmount per servingScore
Vitamin A (Beta-Carotene, Vitamin A Acetate)
1500 mcg RAE
Vitamin C (Acerola Extract, Ascorbic Acid, Ascorbyl Palmitate, Calcium Ascorbate, Magnesium Ascorbate, Niacinamide Ascorbate)
970 mg 58
Vitamin D3 (Cholecalciferol)
50 mcg
Vitamin E (D-Alpha-Tocopherol, D-Alpha-Tocopheryl Succinate)
67 mg
Thiamine (Thiamine Hydrochloride)
125 mg 76
Riboflavin (Riboflavin 5-Phosphate)
50 mg 70
Niacin (Niacinamide, Niacinamide Ascorbate)
190 mg NE
Vitamin B6
105 mg 67
Folate (L-5-Methyltetrahydrofolate, Calcium Salt)
400 mcg DFE
Vitamin B12 (Methylcobalamin)
600 mcg 76
Biotin
3000 mcg 78
Pantothenic Acid (D-Calcium Pantothenate)
600 mg 80
Calcium (Calcium Ascorbate, Calcium D-Glucarate, Calcium D-Pantothenate, Dicalcium Phosphate)
500 mg 70
Iodine (Potassium Iodide)
150 mcg 84
Magnesium (Magnesium Arginate, Magnesium Ascorbate, Magnesium Citrate, Magnesium Glycinate, Magnesium Oxide, Magnesium Taurinate)
420 mg 53
Zinc (L-OptiZinc Zinc Mono-L-Methionine Sulfate, Zinc Citrate)
35 mg 66
Selenium (Se-Methyl L-Selenocysteine, SelenoExcell High Selenium Yeast, Sodium Selenite)
200 mcg 64
Manganese (Manganese Citrate, Manganese Gluconate)
1 mg
Chromium (Crominex 3+ Chromium)
500 mcg 54
Molybdenum (Molybdenum Amino Acid Chelate)
125 mcg 58
Potassium (Potassium Citrate)
35 mg
Broccoli concentrate blend (Broccoli powder, extract, Calcium D-Glucarate)
725 mg
N-Acetyl-L-Cysteine
600 mg
decaffeinated Green Tea extract (Epigallocatechin Gallate)
325 mg 61
Acerola extract
300 mg 35
Inositol
250 mg
Bitter Orange Citrus Bioflavonoids (Hesperidin)
200 mg
Fruit/Berry Proprietary Blend
200 mg
Taurine
200 mg 50
Wild Blueberry Anthocyanin extract
150 mg
Sensoril Ashwagandha extract (Glycoside Conjugates, Oligosaccharides)
125 mg 50
Silymarin (Milk Thistle extract)
100 mg
Trimethylglycine (Betaine Anhydrous)
100 mg
CherryPure Sour Cherry (Tart Cherry) Proanthocyanidin extract
85 mg
Pomella Pomegranate extract (Punicalagins)
85 mg
natural Mixed Tocopherols (Alpha-Tocopherol, Beta-Tocopherol, Delta Tocopherol, Gamma-Tocopherol)
60 mg
MirtoSelect Bilberry extract
30 mg
BioVin Grape Proanthocyanidin extract
25 mg
Leucoselect Grape seed Proanthocyanidin extract
25 mg
Bio-Quercetin Phytosome
15 mg
Bromelain (Pineapple)
15 mg
Lutein (Marigold extract)
15 mg
Olive extract (Hydroxytyrosol, Oleuropein, Polyphenols, Tyrosol)
12.5 mg
Sesame seed Lignan extract
10 mg
Luteolin (Japanese Sophora)
8 mg
Apigenin
5 mg 39
Boron (Boron Amino Acid Chelate)
3 mg 59
Lycopene (LycoBeads natural Tomato extract)
3 mg 70
Delphinidins (Delphinol Maqui berry (Aristotelia chilensis) extract)
2 mg
Cyanidin-3-Glucoside (Black Currant extract)
1.25 mg
Adults 18–50
Report overview
A+ Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyF Value
Each serving provides 150 mcg of iodine as potassium iodide, an amount aligned with daily support. A whole-product serving costs about $1.85.
How this ingredient is rated

Active Ingredient Quality & Bioavailability100

The iodine is identified as potassium iodide, and no marine source is recorded in the saved facts.
Iodine Form & Bioavailability
Potassium iodide is the identified iodine form.
Marine Source Purity & Sourcing
No marine source is recorded, so the marine-specific sourcing check does not apply.

Dose, Safety & Label Transparency100

The label gives 150 mcg of iodine per serving, an amount aligned with daily support and below the evaluated upper limit.
Dosage Efficacy for Daily Support
150 mcg per serving is aligned with daily iodine support.
Dosage Safety & Upper Limits
The 150 mcg serving does not exceed the upper limit used in the evaluation.
Elemental Iodine Transparency
The iodine amount is explicitly stated as 150 mcg per serving.

Value20

A whole-product serving costs about $1.85.
Price Per Effective Serving
A whole-product serving costs about $1.85.
F Active Ingredient Quality & BioavailabilityA- Dose, Safety & Label TransparencyD- Value
An eight-tablet serving provides 500 mcg of chromium from a branded source, but its chemical form is not identified in the saved facts. The whole-product cost is about $0.74 per 200 mcg of chromium.
How this ingredient is rated

Active Ingredient Quality & Bioavailability30

A branded chromium source is recorded, but its chemical form is not identified in the saved facts.
Chromium Chemical Form
The chromium compound is unknown in the saved facts, so its form cannot be assessed.
Branded & Trademarked Sources
A recognized branded chromium source is recorded in the saved facts.

Dose, Safety & Label Transparency85

Each serving provides 500 mcg of chromium; the saved facts do not give a separate weight for the chromium compound.
Elemental Chromium Dosage
Each serving provides 500 mcg of chromium, a substantial amount.
Label Transparency & Disclosure
The chromium amount is given, but a separate compound weight is not recorded in the saved facts.

Value40

The whole-product cost is relatively high when compared per 200 mcg of chromium.
Price per 200 mcg Chromium
The saved price works out to about $0.74 per 200 mcg of chromium, using the cost of the entire product.
F Composition And Label DisclosureA+ Composition And Label Disclosure
+5
Each serving provides 125 mg of ashwagandha, but its preparation is unclear in the saved information. That limits comparison with products that identify an extract or powder.
How this ingredient is rated

Composition and Label Disclosure0

The saved information does not identify the ashwagandha preparation.
Withanolide and Preparation Disclosure
The preparation is unknown in the available information, so its form cannot be compared.

Composition and Label Disclosure100

The ashwagandha amount is individually listed, though its preparation is unclear.
Individual Preparation Amount Disclosure
Each serving lists 125 mg of ashwagandha; its preparation is not identified in the saved information.

Commercial Price and Usability

No commercial price or usability rule was evaluated.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. [Comparative study of the urinary excretion of boron, calcium, magnesium and phosphorus in postmenopausal women with and without osteoporosis].
    José Ramón V; Mora Mora M; Marino Alarcón O; Hernández G; Josefina Linares L; Urdaneta Romero H; Arévalo González E · Investigacion clinica · 2013
    Case-control study45 participantsBone Health forBoron
  2. Effect of dietary boron on mineral, estrogen, and testosterone metabolism in postmenopausal women.
    Nielsen FH; Hunt CD; Mullen LM; Hunt JR · FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 1987
    Single-arm trial12 participantsBone Health forBoron
  3. The relationship between boron and magnesium status and bone mineral density in the human: a review.
    Volpe SL; Taper LJ; Meacham S · Magnesium research · 1994
    Narrative reviewBone Health forBoron
  4. Effects of boron supplementation on bone mineral density and dietary, blood, and urinary calcium, phosphorus, magnesium, and boron in female athletes.
    Meacham SL; Taper LJ; Volpe SL · Environmental health perspectives · 1995
    Randomized trial28 participantsBone Health forBoron
  5. Metabolic responses of postmenopausal women to supplemental dietary boron and aluminum during usual and low magnesium intake: boron, calcium, and magnesium absorption and retention and blood mineral concentrations
    C D Hunt, J L Herbel, F H Nielsen · The American Journal of Clinical Nutrition · 1997
    Non-randomized trial11 participantsBone Health forBoron
  6. What is the impact of daily oral supplementation of vitamin D3 (cholecalciferol) plus calcium on the incidence of hip fracture in older people? A systematic review and meta-analysis.
    Manoj P; Derwin R; George S · International journal of older people nursing · 2023
    Meta-analysis12,620 participants7 studies pooledBone Health forCalcium
  7. Calcium supplementation prevents seasonal bone loss and changes in biochemical markers of bone turnover in elderly New England women: a randomized placebo-controlled trial.
    Storm D; Eslin R; Porter ES; Musgrave K; Vereault D; Patton C; Kessenich C; Mohan S; Chen T; Holick MF; Rosen CJ · The Journal of clinical endocrinology and metabolism · 1998
    Randomized trial60 participantsBone Health forCalcium
  8. The effects of calcium supplementation (milk powder or tablets) and exercise on bone density in postmenopausal women.
    Prince R; Devine A; Dick I; Criddle A; Kerr D; Kent N; Price R; Randell A · Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 1995
    Randomized trial168 participantsBone Health forCalcium
  9. The efficacy of calcium supplementation alone in elderly Thai women over a 2-year period: a randomized controlled trial.
    Rajatanavin R; Chailurkit L; Saetung S; Thakkinstian A; Nimitphong H · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2014
    Randomized trial404 participantsBone Health forCalcium
  10. Calcium-enriched foods and bone mass growth in prepubertal girls: a randomized, double-blind, placebo-controlled trial.
    Bonjour JP; Carrie AL; Ferrari S; Clavien H; Slosman D; Theintz G; Rizzoli R · The Journal of clinical investigation · 1997
    Randomized trial149 participantsBone Health forCalcium
  11. Association between RBC folate and lumbar bone mineral density in postmenopausal women, a cross-sectional study from NHANES 2009-2018.
    Wei H; Jin Z; Zhou L; Tang G; Chai S; Che X; Tan Y; Zeng W · Frontiers in endocrinology · 2025
    Cross-sectional study1,315 participantsBone Health forFolate
  12. Genetic variants modify the associations of concentrations of methylmalonic acid, vitamin B-12, vitamin B-6, and folate with bone mineral density.
    Liu CT; Karasik D; Xu H; Zhou Y; Broe K; Cupples LA; Cpgm de Groot L; Ham A; Hannan MT; Hsu YH; Jacques P; McLean RR; Paul L; Selhub J; Trajanoska K; van der Velde N; van Schoor N; Kiel DP · The American journal of clinical nutrition · 2021
    Cohort study4,310 participantsBone Health forFolate
  13. Adequate Intake and Supplementation of B Vitamins, in Particular Folic Acid, can Play a Protective Role in Bone Health.
    Rondanelli M; Tartara A; Fossari F; Vecchio V; Faliva MA; Naso M; Perna S; Nichetti M; Peroni G · Current aging science · 2022
    Narrative review35,298 participants29 studies pooledBone Health forFolate Bone Health forVitamin B6
  14. Relation of homocysteine, folate, and vitamin B12 to bone mineral density of postmenopausal women.
    Cagnacci A; Baldassari F; Rivolta G; Arangino S; Volpe A · Bone · 2004
    Cross-sectional study161 participantsBone Health forFolate
  15. Dietary intake of folate, but not vitamin B2 or B12, is associated with increased bone mineral density 5 years after the menopause: results from a 10-year follow-up study in early postmenopausal women.
    Rejnmark L; Vestergaard P; Hermann AP; Brot C; Eiken P; Mosekilde L · Calcified tissue international · 2008
    Cohort study1,869 participantsBone Health forFolate
  16. Association between Serum Magnesium and Fractures: A Systematic Review and Meta-Analysis of Observational Studies.
    Dominguez LJ; Veronese N; Ciriminna S; Pérez-Albela JL; Vásquez-López VF; Rodas-Regalado S; Di Bella G; Parisi A; Tagliaferri F; Barbagallo M · Nutrients · 2023
    Meta-analysis119,755 participants4 studies pooledBone Health forMagnesium
  17. Bioabsorbable Magnesium-Based Materials Potential and Safety in Bone Surgery: A Systematic Review.
    Hung CH; Kwok YC; Yip J; Wong HH; Leung YY · Craniomaxillofacial trauma & reconstruction · 2025
    Systematic review386 participants8 studies pooledBone Health forMagnesium
  18. Vascularized bone grafting fixed by biodegradable magnesium screw for treating osteonecrosis of the femoral head.
    Zhao D; Huang S; Lu F; Wang B; Yang L; Qin L; Yang K; Li Y; Li W; Wang W; Tian S; Zhang X; Gao W; Wang Z; Zhang Y; Xie X; Wang J; Li J · Biomaterials · 2016
    Randomized trial48 participantsBone Health forMagnesium
  19. An update on magnesium and bone health.
    Rondanelli M; Faliva MA; Tartara A; Gasparri C; Perna S; Infantino V; Riva A; Petrangolini G; Peroni G · Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2022
    Narrative reviewBone Health forMagnesium
  20. Sex-specific differences in the association of magnesium intake with femoral neck bone mineral density among older adults.
    Wang B; Tan X; Yao X; Zhu Z · Endocrine connections · 2025
    Cross-sectional study1,343 participantsBone Health forMagnesium