Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.
- One-carbon metabolism-related compounds are associated with epigenetic aging biomarkers: results from the cross-sectional National Health and Nutrition Examination Survey 1999-2002.
Bozack AK; Khodasevich D; Nwanaji-Enwerem JC; Gladish N; Shen H; Daredia S; Gamble M; Needham BL; Rehkopf DH; Cardenas A · The American journal of clinical nutrition · 2025
Cross-sectional study2,346 participantsflagAnti-Aging forscienceFolate
- Longitudinal associations of one-carbon metabolism biomarkers with biological and epigenetic aging in older adults in India.
Wang J; Crimmins E; Kim JK; Chang NS; Dey S; Lee J; Thyagarajan B; Vivek S · GeroScience · 2026
Cohort studyflagAnti-Aging forscienceFolate
- Associations between leukocyte telomere length and three measures of folate status: a cross-sectional analysis of NHANES 1999-2002.
Xue Q; Chen H · Frontiers in nutrition · 2026
Cross-sectional study7,324 participantsflagAnti-Aging forscienceFolate
- Homocysteine versus the vitamins folate, B6, and B12 as predictors of cognitive function and decline in older high-functioning adults: MacArthur Studies of Successful Aging.
Kado DM; Karlamangla AS; Huang MH; Troen A; Rowe JW; Selhub J; Seeman TE · The American journal of medicine · 2005
Cohort study499 participantsflagAnti-Aging forscienceFolate
- Blood folate is associated with asymptomatic or partially symptomatic Alzheimer's disease in the Nun study.
Wang H; Odegaard A; Thyagarajan B; Hayes J; Cruz KS; Derosiers MF; Tyas SL; Gross MD · Journal of Alzheimer's disease : JAD · 2012
Cohort study60 participantsflagAnti-Aging forscienceFolate
- Selenium Concentrations and Mortality among Community-Dwelling Older Adults: Results from IlSIRENTE Study.
Giovannini S; Onder G; Lattanzio F; Bustacchini S; Di Stefano G; Moresi R; Russo A; Bernabei R; Landi F · The journal of nutrition, health & aging · 2019
Cohort study347 participantsflagAnti-Aging forscienceSelenium
- Selenium and mortality in the elderly: results from the EVA study.
Akbaraly NT; Arnaud J; Hininger-Favier I; Gourlet V; Roussel AM; Berr C · Clinical chemistry · 2005
Randomized trialflagAnti-Aging forscienceSelenium
- Association of dietary selenium intake and all-cause mortality of Parkinson's disease and its interaction with blood cadmium level: a retrospective cohort study.
Tu X; Wu N; Wan Y; Gan J; Liu Z; Song L · BMC geriatrics · 2024
Cohort study184 participantsflagAnti-Aging forscienceSelenium
- Selenium alleviates cadmium-induced biological aging acceleration and the potential mediating role of inflammation.
Li C; Xiang Y; Liu M; Wang Z; Wu Y; Yang Q; Huang L · Ecotoxicology and environmental safety · 2025
Cross-sectional study7,433 participantsflagAnti-Aging forscienceSelenium
- Minerals and Sarcopenia; The Role of Calcium, Iron, Magnesium, Phosphorus, Potassium, Selenium, Sodium, and Zinc on Muscle Mass, Muscle Strength, and Physical Performance in Older Adults: A Systematic Review.
van Dronkelaar C; van Velzen A; Abdelrazek M; van der Steen A; Weijs PJM; Tieland M · Journal of the American Medical Directors Association · 2019
Systematic review10 studies pooledflagAnti-Aging forscienceSelenium
- Non-linear association between serum levels of vitamins A and B12 and accelerated epigenetic aging.
Ma Z; An M; Gong W; Chen X; Liang M; Zhang J; Du X; Lu F; He Q; Wang M; Zhong J; Sun C · Frontiers in nutrition · 2025
Cross-sectional study2,530 participantsflagAnti-Aging forscienceVitamin B12
- Gender-specific impact of personal health parameters on individual brain aging in cognitively unimpaired elderly subjects.
Franke K; Ristow M; Gaser C; Alzheimer's Disease Neuroimaging Initiative · Frontiers in aging neuroscience · 2014
Cross-sectional study228 participantsflagAnti-Aging forscienceVitamin B12
- Homocysteine and the risk of nursing home admission and mortality in older persons.
Swart KM; van Schoor NM; Blom HJ; Smulders YM; Lips P · European journal of clinical nutrition · 2012
Cohort study1,117 participantsflagAnti-Aging forscienceVitamin B12
- Dynamics and interactions of cobalamin and folate status during advanced aging - a longitudinal study in a community-dwelling cohort with multiple follow-ups.
Jungert A; Zenke-Philippi C; Neuhäuser-Berthold M · Nutrition journal · 2021
Cohort study332 participantsflagAnti-Aging forscienceVitamin B12
- Association between serum vitamin B12 and risk of all-cause mortality in elderly adults: a prospective cohort study.
Xu K; Liu X; Liu J; Zhang Y; Ding X; Li L; Sun J · BMC geriatrics · 2021
Cohort study2,086 participantsflagAnti-Aging forscienceVitamin B12
- Low dietary vitamin E intake is associated with high risk of incident dementia among older adults: The Shanghai Aging Study.
Liu S; Luo J; Xiao Z; Wu W; Liang X; Ding S; Zhao Q; Zhao X; Wang Y; Ding D · Frontiers in nutrition · 2024
Cohort study1,550 participantsflagAnti-Aging forscienceVitamin E
- Nutrients and bioactives in green leafy vegetables and cognitive decline: Prospective study.
Morris MC; Wang Y; Barnes LL; Bennett DA; Dawson-Hughes B; Booth SL · Neurology · 2019
Cohort study960 participantsflagAnti-Aging forscienceVitamin E
- Low Intake of Vitamin E Accelerates Cellular Aging in Patients With Established Cardiovascular Disease: The CORDIOPREV Study.
Corina A; Rangel-Zúñiga OA; Jiménez-Lucena R; Alcalá-Díaz JF; Quintana-Navarro G; Yubero-Serrano EM; López-Moreno J; Delgado-Lista J; Tinahones F; Ordovás JM; López-Miranda J; Pérez-Martínez P · The journals of gerontology. Series A, Biological sciences and medical sciences · 2020
Observational study1,002 participantsflagAnti-Aging forscienceVitamin E
- The L-shaped link between total antioxidant capacity and phenotypic age acceleration: evidence from NHANES 2003-2010.
Wu Y; Xiang M; Zhao Y; Zhang Y; Cheng W; Deng J · Biogerontology · 2025
Cross-sectional study16,395 participantsflagAnti-Aging forscienceVitamin E
- Serum levels of vitamin E forms and risk of cognitive impairment in a Finnish cohort of older adults.
Mangialasche F; Solomon A; Kåreholt I; Hooshmand B; Cecchetti R; Fratiglioni L; Soininen H; Laatikainen T; Mecocci P; Kivipelto M · Experimental gerontology · 2014
Cohort study140 participantsflagAnti-Aging forscienceVitamin E
- Selenium and the course of mild Graves' orbitopathy.
Marcocci C; Kahaly GJ; Krassas GE; Bartalena L; Prummel M; Stahl M; Altea MA; Nardi M; Pitz S; Boboridis K; Sivelli P; von Arx G; Mourits MP; Baldeschi L; Bencivelli W; Wiersinga W; European Group on Graves' Orbitopathy · The New England journal of medicine · 2011
Randomized trial159 participantsflagAnti-Inflammatory Support forscienceSelenium
- Effects of selenium supplementation on glucose homeostasis, inflammation, and oxidative stress in gestational diabetes: Randomized, double-blind, placebo-controlled trial.
Asemi Z; Jamilian M; Mesdaghinia E; Esmaillzadeh A · Nutrition (Burbank, Los Angeles County, Calif.) · 2016
Randomized trial70 participantsflagAnti-Inflammatory Support flagMetabolism Boost forscienceSelenium
- Selenium Supplementation Affects Insulin Resistance and Serum hs-CRP in Patients with Type 2 Diabetes and Coronary Heart Disease.
Farrokhian A; Bahmani F; Taghizadeh M; Mirhashemi SM; Aarabi MH; Raygan F; Aghadavod E; Asemi Z · Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme · 2017
Randomized trial60 participantsflagAnti-Inflammatory Support forscienceSelenium
- The effects of selenium supplementation on cardiovascular risk factors in patients with metabolic diseases ‒ A systematic review and meta-analysis of randomized controlled trials.
Qiu W; Huang N; Zhang K; Qiu H; Guo Z; Han F; Sun X; Hou N; Kan C · Nutricion hospitalaria · 2026
Meta-analysis656 participants11 studies pooledflagAnti-Inflammatory Support forscienceSelenium
- Effects of Selenium Supplementation on Metabolic Status in Patients Undergoing for Coronary Artery Bypass Grafting (CABG) Surgery: a Randomized, Double-Blind, Placebo-Controlled Trial.
Kamali A; Amirani E; Asemi Z · Biological trace element research · 2020
Randomized trial33 participantsflagAnti-Inflammatory Support forscienceSelenium
- Efficacy of Vitamin C as Glucocorticoid Substitute for Reducing Pain and Inflammation After Total Hip Arthroplasty: A Randomized Controlled Trial.
Jiang W; Xu H; Jiang X; Zhan Y; Ju Y; Xie J; Huang Z; Huang Q; Pei F · The Journal of bone and joint surgery. American volume · 2025
Randomized trial107 participantsflagAnti-Inflammatory Support forscienceVitamin C
- The Impact of Vitamin C on Analgesic, Anti-inflammatory, and Hemostatic Outcomes After Total Hip and Knee Arthroplasty: A Systematic Review and Meta-Analysis.
Moftakhari Hajimirzaei S; Bagherzadeh Cham M; Dolikhani M; Tabatabaee SM; Ebrahimpour A · The archives of bone and joint surgery · 2026
Meta-analysis1,162 participants10 studies pooledflagAnti-Inflammatory Support forscienceVitamin C
- The impact of vitamin C supplementation on the perioperative outcomes after total hip and knee arthroplasty: a systematic review and meta-analysis.
Liu X; Guo J; Li Y; Yang Y; Liu M; Gao Q; Yang Y; Wu X; Yue C · BMC musculoskeletal disorders · 2026
Meta-analysis852 participants8 studies pooledflagAnti-Inflammatory Support forscienceVitamin C
- Therapeutic Impact of Ascorbic Acid on Oral and Periodontal Tissues: A Systematic Literature Review.
Ruzijevaite G; Acaite E; Jagelaviciene E · Medicina (Kaunas, Lithuania) · 2025
Systematic review811 participants17 studies pooledflagAnti-Inflammatory Support forscienceVitamin C
- Oral vitamin C administration reduces early recurrence rates after electrical cardioversion of persistent atrial fibrillation and attenuates associated inflammation.
Korantzopoulos P; Kolettis TM; Kountouris E; Dimitroula V; Karanikis P; Pappa E; Siogas K; Goudevenos JA · International journal of cardiology · 2005
Randomized trial44 participantsflagAnti-Inflammatory Support forscienceVitamin C
- Vitamin D deficiency and C-reactive protein: a bidirectional Mendelian randomization study.
Zhou A; Hyppönen E · International journal of epidemiology · 2023
Observational study294,970 participantsflagAnti-Inflammatory Support forscienceVitamin D
- Vitamin D in Children With Inflammatory Bowel Disease: A Randomized Controlled Clinical Trial.
El Amrousy D; El Ashry H; Hodeib H; Hassan S · Journal of clinical gastroenterology · 2021
Randomized trial120 participantsflagAnti-Inflammatory Support forscienceVitamin D
- Vitamin D supplementation reduces infection rate and promotes wound healing in patients with diabetic foot ulcers.
Gao YQ; Gao YH; Xing JH · World journal of diabetes · 2025
Randomized trial120 participantsflagAnti-Inflammatory Support forscienceVitamin D
- Associations of C-reactive Protein with 25-hydroxyvitamin D in 24 Specific Diseases: A Cross-sectional Study from NHANES.
Yang F; Sun M; Sun C; Li J; Yang X; Bi C; Wang M; Pu L; Wang J; Wang C; Xie M; Yao Y; Jin L · Scientific reports · 2020
Cross-sectional study9,809 participantsflagAnti-Inflammatory Support forscienceVitamin D
- Combined effects of vitamin D deficiency and systemic inflammation on all-cause mortality and cause-specific mortality in older adults.
Zhang C; Cui J; Li S; Shen J; Luo X; Yao Y; Shi H · BMC geriatrics · 2024
Cohort study3,072 participantsflagAnti-Inflammatory Support forscienceVitamin D
- Effects of delta-tocotrienol supplementation on Glycemic Control, oxidative stress, inflammatory biomarkers and miRNA expression in type 2 diabetes mellitus: A randomized control trial.
Mahjabeen W; Khan DA; Mirza SA; Pervez MA · Phytotherapy research : PTR · 2021
Randomized trial110 participantsflagAnti-Inflammatory Support forscienceVitamin E
- Effect of vitamin E supplementation on serum C-reactive protein level: a meta-analysis of randomized controlled trials.
Saboori S; Shab-Bidar S; Speakman JR; Yousefi Rad E; Djafarian K · European journal of clinical nutrition · 2016
Meta-analysis495 participants12 studies pooledflagAnti-Inflammatory Support forscienceVitamin E
- Efficacy of Nutritional Interventions on Inflammatory Markers in Haemodialysis Patients: A Systematic Review and Limited Meta-Analysis.
Khor BH; Narayanan SS; Sahathevan S; Gafor AHA; Daud ZAM; Khosla P; Sabatino A; Fiaccadori E; Chinna K; Karupaiah T · Nutrients · 2018
Meta-analysis46 studies pooledflagAnti-Inflammatory Support forscienceVitamin E
- Vitamin E improves serum markers and histology in adults with metabolic dysfunction-associated steatotic liver disease: Systematic review and meta-analysis.
Chee NM; Sinnanaidu RP; Chan WK · Journal of gastroenterology and hepatology · 2024
Meta-analysis8 studies pooledflagAnti-Inflammatory Support forscienceVitamin E
- Delta-tocotrienol supplementation improves biochemical markers of hepatocellular injury and steatosis in patients with nonalcoholic fatty liver disease: A randomized, placebo-controlled trial.
Pervez MA; Khan DA; Slehria AUR; Ijaz A · Complementary therapies in medicine · 2021
Randomized trial71 participantsflagAnti-Inflammatory Support forscienceVitamin E
- Zinc decreases C-reactive protein, lipid peroxidation, and inflammatory cytokines in elderly subjects: a potential implication of zinc as an atheroprotective agent.
Bao B; Prasad AS; Beck FW; Fitzgerald JT; Snell D; Bao GW; Singh T; Cardozo LJ · The American journal of clinical nutrition · 2010
Randomized trial40 participantsflagAnti-Inflammatory Support forscienceZinc
- Zinc Supplementation in Individuals with Prediabetes and type 2 Diabetes: a GRADE-Assessed Systematic Review and Dose-Response Meta-analysis.
Nazari M; Nikbaf-Shandiz M; Pashayee-Khamene F; Bagheri R; Goudarzi K; Hosseinnia NV; Dolatshahi S; Omran HS; Amirani N; Ashtary-Larky D; Asbaghi O; Ghanavati M · Biological trace element research · 2024
Meta-analysis23 studies pooledflagAnti-Inflammatory Support forscienceZinc
- The Effects of Zinc Supplementation on C-Reactive Protein and Inflammatory Cytokines: A Meta-Analysis and Systematical Review.
Ceylan MN; Akdas S; Yazihan N · Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research · 2022
Meta-analysis73 studies pooledflagAnti-Inflammatory Support forscienceZinc
- The Effects of Zinc Sulfate Supplementation on Serum Copeptin, C-Reactive Protein and Metabolic Markers in Zinc-Deficient Diabetic Patients on Hemodialysis: A Randomized, Double-Blind, Placebo-Controlled Trial.
Hosseini R; Montazerifar F; Shahraki E; Karajibani M; Mokhtari AM; Dashipour AR; Ferns GA; Jalali M · Biological trace element research · 2021
Randomized trial46 participantsflagAnti-Inflammatory Support forscienceZinc
- Zinc supplementation and cardiovascular disease risk factors: A GRADE-assessed systematic review and dose-response meta-analysis.
Nazari M; Ashtary-Larky D; Nikbaf-Shandiz M; Goudarzi K; Bagheri R; Dolatshahi S; Omran HS; Amirani N; Ghanavati M; Asbaghi O · Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) · 2023
Meta-analysis75 studies pooledflagAnti-Inflammatory Support forscienceZinc
- [Comparative study of the urinary excretion of boron, calcium, magnesium and phosphorus in postmenopausal women with and without osteoporosis].
José Ramón V; Mora Mora M; Marino Alarcón O; Hernández G; Josefina Linares L; Urdaneta Romero H; Arévalo González E · Investigacion clinica · 2013
Case-control study45 participantsflagBone Health forscienceBoron
- Effect of dietary boron on mineral, estrogen, and testosterone metabolism in postmenopausal women.
Nielsen FH; Hunt CD; Mullen LM; Hunt JR · FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 1987
Single-arm trial12 participantsflagBone Health forscienceBoron
- The relationship between boron and magnesium status and bone mineral density in the human: a review.
Volpe SL; Taper LJ; Meacham S · Magnesium research · 1994
Narrative reviewflagBone Health forscienceBoron
- Effects of boron supplementation on bone mineral density and dietary, blood, and urinary calcium, phosphorus, magnesium, and boron in female athletes.
Meacham SL; Taper LJ; Volpe SL · Environmental health perspectives · 1995
Randomized trial28 participantsflagBone Health forscienceBoron
- Metabolic responses of postmenopausal women to supplemental dietary boron and aluminum during usual and low magnesium intake: boron, calcium, and magnesium absorption and retention and blood mineral concentrations
C D Hunt, J L Herbel, F H Nielsen · The American Journal of Clinical Nutrition · 1997
Non-randomized trial11 participantsflagBone Health forscienceBoron
- What is the impact of daily oral supplementation of vitamin D3 (cholecalciferol) plus calcium on the incidence of hip fracture in older people? A systematic review and meta-analysis.
Manoj P; Derwin R; George S · International journal of older people nursing · 2023
Meta-analysis12,620 participants7 studies pooledflagBone Health forscienceCalcium
- Calcium supplementation prevents seasonal bone loss and changes in biochemical markers of bone turnover in elderly New England women: a randomized placebo-controlled trial.
Storm D; Eslin R; Porter ES; Musgrave K; Vereault D; Patton C; Kessenich C; Mohan S; Chen T; Holick MF; Rosen CJ · The Journal of clinical endocrinology and metabolism · 1998
Randomized trial60 participantsflagBone Health forscienceCalcium
- The effects of calcium supplementation (milk powder or tablets) and exercise on bone density in postmenopausal women.
Prince R; Devine A; Dick I; Criddle A; Kerr D; Kent N; Price R; Randell A · Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 1995
Randomized trial168 participantsflagBone Health forscienceCalcium
- The efficacy of calcium supplementation alone in elderly Thai women over a 2-year period: a randomized controlled trial.
Rajatanavin R; Chailurkit L; Saetung S; Thakkinstian A; Nimitphong H · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2014
Randomized trial404 participantsflagBone Health forscienceCalcium
- Calcium-enriched foods and bone mass growth in prepubertal girls: a randomized, double-blind, placebo-controlled trial.
Bonjour JP; Carrie AL; Ferrari S; Clavien H; Slosman D; Theintz G; Rizzoli R · The Journal of clinical investigation · 1997
Randomized trial149 participantsflagBone Health forscienceCalcium
- The Association between Dietary and Circulating Copper Levels and Osteoporosis: a Scoping Review.
Ju Y; Xiong W; Pang Y; Chen Z; Hou J; Zheng S; Li Z; Liu T; Xia H; Xia M; Zhong Y; Li J; Jiang X · Biological trace element research · 2026
Scoping review18 studies pooledflagBone Health forscienceCopper
- Association between dietary copper, iron, zinc, selenium intake and osteopenia or osteoporosis in elderly hypertensive patients: a retrospective cohort study.
Chen M; Jia L; Gao R · Frontiers in nutrition · 2024
Cohort study5,286 participantsflagBone Health forscienceCopper
- Associations of dietary copper intake with total bone mineral density and lumbar spine bone mineral density in American adults.
Hu M; Wang Z; Li C; Zheng Y; Hu J · Medicine · 2025
Cross-sectional studyflagBone Health forscienceCopper
- The association between dietary mineral intake and bone mineral density: a cross-sectional study.
Wei M; Wei J; Huang S · Journal of health, population, and nutrition · 2025
Cross-sectional study11,520 participantsflagBone Health forscienceCopper
- Association between dietary copper intake and bone mineral density in children and adolescents aged 8-19 years: A cross-sectional study.
Cui A; Yan J; Li H; Fan Z; Wei X; Wang H; Zhuang Y · PloS one · 2024
Cross-sectional study6,965 participantsflagBone Health forscienceCopper
- Association between Serum Magnesium and Fractures: A Systematic Review and Meta-Analysis of Observational Studies.
Dominguez LJ; Veronese N; Ciriminna S; Pérez-Albela JL; Vásquez-López VF; Rodas-Regalado S; Di Bella G; Parisi A; Tagliaferri F; Barbagallo M · Nutrients · 2023
Meta-analysis119,755 participants4 studies pooledflagBone Health forscienceMagnesium
- Bioabsorbable Magnesium-Based Materials Potential and Safety in Bone Surgery: A Systematic Review.
Hung CH; Kwok YC; Yip J; Wong HH; Leung YY · Craniomaxillofacial trauma & reconstruction · 2025
Systematic review386 participants8 studies pooledflagBone Health forscienceMagnesium
- Vascularized bone grafting fixed by biodegradable magnesium screw for treating osteonecrosis of the femoral head.
Zhao D; Huang S; Lu F; Wang B; Yang L; Qin L; Yang K; Li Y; Li W; Wang W; Tian S; Zhang X; Gao W; Wang Z; Zhang Y; Xie X; Wang J; Li J · Biomaterials · 2016
Randomized trial48 participantsflagBone Health forscienceMagnesium
- An update on magnesium and bone health.
Rondanelli M; Faliva MA; Tartara A; Gasparri C; Perna S; Infantino V; Riva A; Petrangolini G; Peroni G · Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2022
Narrative reviewflagBone Health forscienceMagnesium
- Sex-specific differences in the association of magnesium intake with femoral neck bone mineral density among older adults.
Wang B; Tan X; Yao X; Zhu Z · Endocrine connections · 2025
Cross-sectional study1,343 participantsflagBone Health forscienceMagnesium
- Risk of Environmental Chemicals on Bone Fractures Is Independent of Low Bone Mass in US Adults: Insights from 2017 to 2018 NHANES.
Ling R; Ai Y; Chen C; Zhang J; Zou Z; Cheng S; Li C; Li X; Wang B · Metabolites · 2023
Cross-sectional study2,640 participantsflagBone Health forscienceManganese
- The Manganese-Bone Connection: Investigating the Role of Manganese in Bone Health.
Taskozhina G; Batyrova G; Umarova G; Issanguzhina Z; Kereyeva N · Journal of clinical medicine · 2024
Narrative reviewflagBone Health forscienceManganese
- Associations of multiple metals with bone mineral density: A population-based study in US adults.
Wei MH; Cui Y; Zhou HL; Song WJ; Di DS; Zhang RY; Huang Q; Liu JA; Wang Q · Chemosphere · 2021
Cross-sectional studyflagBone Health forscienceManganese
- Sex-specific associations of urinary mixed-metal concentrations with femoral bone mineral density among older people: an NHANES (2017-2020) analysis.
Li H; Li G; Yi M; Zhou J; Deng Y; Huang Y; He S; Meng X; Liu L · Frontiers in public health · 2024
Cross-sectional study31 participantsflagBone Health forscienceManganese
- Relationship between blood manganese and bone mineral density and bone mineral content in adults: A population-based cross-sectional study.
Wang C; Zhu Y; Long H; Ou M; Zhao S · PloS one · 2022
Cross-sectional study9,732 participantsflagBone Health forscienceManganese
- Pregnancy vitamin D supplementation and offspring bone mineral density in childhood follow-up of a randomized controlled trial.
Moon RJ; D' Angelo S; Curtis EM; Ward KA; Crozier SR; Schoenmakers I; Javaid MK; Bishop NJ; Godfrey KM; Cooper C; Harvey NC; MAVIDOS Trial Group · The American journal of clinical nutrition · 2024
Randomized trial454 participantsflagBone Health forscienceVitamin D
- Vitamin D analogs and bone: preclinical and clinical studies with eldecalcitol.
Matsumoto T; Takano T; Saito H; Takahashi F · BoneKEy reports · 2014
Narrative reviewflagBone Health forscienceVitamin D
- Efficacy of vitamin D fortified foods on bone mineral density and serum bone biomarkers: A systematic review and meta-analysis of interventional studies.
Tangestani H; Djafarian K; Emamat H; Arabzadegan N; Shab-Bidar S · Critical reviews in food science and nutrition · 2020
Meta-analysis1,786 participants20 studies pooledflagBone Health forscienceVitamin D
- Cholecalciferol Supplementation Attenuates Bone Loss in Incident Kidney Transplant Recipients: A Prespecified Secondary Endpoint Analysis of a Randomized Controlled Trial.
Tsujita M; Doi Y; Obi Y; Hamano T; Tomosugi T; Futamura K; Okada M; Hiramitsu T; Goto N; Isaka Y; Takeda A; Narumi S; Watarai Y · Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2022
Randomized trial193 participantsflagBone Health forscienceVitamin D
- Vitamin D supplementation and bone health in post-menopausal women: a 24-month randomized controlled intervention with enhanced bioavailability formulations.
Rasool N; Munir Y · European journal of clinical nutrition · 2026
Randomized trial612 participantsflagBone Health forscienceVitamin D
- Vitamin K and the prevention of fractures: systematic review and meta-analysis of randomized controlled trials.
Cockayne S; Adamson J; Lanham-New S; Shearer MJ; Gilbody S; Torgerson DJ · Archives of internal medicine · 2006
Meta-analysis13 studies pooledflagBone Health forscienceVitamin K
- Three-year low-dose menaquinone-7 supplementation helps decrease bone loss in healthy postmenopausal women.
Knapen MH; Drummen NE; Smit E; Vermeer C; Theuwissen E · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2014
Randomized trial244 participantsflagBone Health forscienceVitamin K
- Effect of combined administration of vitamin D3 and vitamin K2 on bone mineral density of the lumbar spine in postmenopausal women with osteoporosis.
Iwamoto J; Takeda T; Ichimura S · Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association · 2001
Randomized trial92 participantsflagBone Health forscienceVitamin K
- Efficacy and safety of vitamin K2 for postmenopausal women with osteoporosis at a long-term follow-up: meta-analysis and systematic review.
Zhou M; Han S; Zhang W; Wu D · Journal of bone and mineral metabolism · 2022
Meta-analysis6,853 participants9 studies pooledflagBone Health forscienceVitamin K
- Low-dose vitamin K2 (MK-4) supplementation for 12 months improves bone metabolism and prevents forearm bone loss in postmenopausal Japanese women.
Koitaya N; Sekiguchi M; Tousen Y; Nishide Y; Morita A; Yamauchi J; Gando Y; Miyachi M; Aoki M; Komatsu M; Watanabe F; Morishita K; Ishimi Y · Journal of bone and mineral metabolism · 2015
Randomized trial48 participantsflagBone Health forscienceVitamin K
- Associations of dietary folate, vitamin B6 and B12 intake with cardiovascular outcomes in 115664 participants: a large UK population-based cohort.
Zhang B; Dong H; Xu Y; Xu D; Sun H; Han L · European journal of clinical nutrition · 2023
Cohort study115,664 participantsflagCardiovascular Support forscienceFolate
- Folate, Homocysteine, and Adverse Outcomes After Ischemic Stroke.
Shi M; Zheng J; Liu Y; Mao X; Wu X; Chu M; Niu H; Sun L; Chang X; He Y; Liu Y; Guo D; Zhang Y; Zhu Z; Zhao J · Journal of the American Heart Association · 2024
Cohort study3,530 participantsflagCardiovascular Support forscienceFolate
- Effect of folic acid on endothelial function following acute myocardial infarction.
Moens AL; Claeys MJ; Wuyts FL; Goovaerts I; Van Hertbruggen E; Wendelen LC; Van Hoof VO; Vrints CJ · The American journal of cardiology · 2007
Randomized trial40 participantsflagCardiovascular Support forscienceFolate
- Folic acid enhances endothelial function and reduces blood pressure in smokers: a randomized controlled trial.
Mangoni AA; Sherwood RA; Swift CG; Jackson SH · Journal of internal medicine · 2003
Randomized trial24 participantsflagCardiovascular Support forscienceFolate
- 5-methyltetrahydrofolate, the active form of folic acid, restores endothelial function in familial hypercholesterolemia.
Verhaar MC; Wever RM; Kastelein JJ; van Dam T; Koomans HA; Rabelink TJ · Circulation · 1998
Non-randomized trial20 participantsflagCardiovascular Support forscienceFolate
- Circulating and dietary magnesium and risk of cardiovascular disease: a systematic review and meta-analysis of prospective studies.
Del Gobbo LC; Imamura F; Wu JH; de Oliveira Otto MC; Chiuve SE; Mozaffarian D · The American journal of clinical nutrition · 2013
Meta-analysis313,041 participants16 studies pooledflagCardiovascular Support forscienceMagnesium
- Magnesium and the risk of cardiovascular events: a meta-analysis of prospective cohort studies.
Qu X; Jin F; Hao Y; Li H; Tang T; Wang H; Yan W; Dai K · PloS one · 2013
Meta-analysis532,979 participants19 studies pooledflagCardiovascular Support forscienceMagnesium
- Quantitative Association Between Serum/Dietary Magnesium and Cardiovascular Disease/Coronary Heart Disease Risk: A Dose-Response Meta-analysis of Prospective Cohort Studies.
Zhao L; Hu M; Yang L; Xu H; Song W; Qian Y; Zhao M · Journal of cardiovascular pharmacology · 2020
Meta-analysis544,581 participants18 studies pooledflagCardiovascular Support flagHeart Health forscienceMagnesium
- Comparative Efficacy of Nutraceuticals on Endothelial Function: A Systematic Review and Network Meta-Analysis.
Norouzzadeh M; Rashedi MH; Mahdavi-Mazdeh G; Kosari A; Shahinfar H · Current atherosclerosis reports · 2026
Meta-analysisflagCardiovascular Support flagHeart Health forscienceMagnesium
- Serum magnesium, mortality, and cardiovascular disease in chronic kidney disease and end-stage renal disease patients: a systematic review and meta-analysis.
Xiong J; He T; Wang M; Nie L; Zhang Y; Wang Y; Huang Y; Feng B; Zhang J; Zhao J · Journal of nephrology · 2020
Meta-analysis200,934 participants20 studies pooledflagCardiovascular Support forscienceMagnesium
- Effect of supplementation with high-selenium yeast on plasma lipids: a randomized trial.
Rayman MP; Stranges S; Griffin BA; Pastor-Barriuso R; Guallar E · Annals of internal medicine · 2011
Randomized trial501 participantsflagCardiovascular Support forscienceSelenium
- Association of selenium and cadmium with heart failure and mortality based on the National Health and Nutrition Examination Survey.
Xing X; Xu M; Yang L; Shao C; Wang Y; Qi M; Niu X; Gao D · Journal of human nutrition and dietetics : the official journal of the British Dietetic Association · 2023
Cohort study15,689 participantsflagCardiovascular Support forscienceSelenium
- Higher serum selenium concentration is associated with lower risk of all-cause and cardiovascular mortality among individuals with chronic kidney disease: A population-based cohort study of NHANES.
Zhu D; Zhong Q; Lin T; Song T · Frontiers in nutrition · 2023
Cohort study3,063 participantsflagCardiovascular Support forscienceSelenium
- Selenium status in the body and cardiovascular disease: a systematic review and meta-analysis.
Kuria A; Tian H; Li M; Wang Y; Aaseth JO; Zang J; Cao Y · Critical reviews in food science and nutrition · 2021
Meta-analysis13 studies pooledflagCardiovascular Support forscienceSelenium
- Associations of selenium status with all-cause and cause-specific mortality: a systematic review and meta-analysis of cohort studies.
Cui Z; Xie R; Lu X; Schomburg L; Brenner H; Schöttker B · Redox biology · 2025
Meta-analysis95 participants20 studies pooledflagCardiovascular Support flagGeneral Health forscienceSelenium
- Vitamin B12 Status and Cardiovascular Risk: Novel Insights from NMR-Based Lipoprotein Profiling in 20,665 Adults.
Eken Y; Tekin N; Şahin F; Tay İ; Yıldırım Saral N; Serteser M; Baykal AT · Journal of clinical medicine · 2026
Cross-sectional study20,665 participantsflagCardiovascular Support flagHeart Health forscienceVitamin B12
- Pregnancy Metal Mixtures and Blood Pressure and Hypertension in Mid-Life: A Prospective U.S. Cohort Study.
Zhang M; Aris IM; Cardenas A; Rifas-Shiman SL; Lin PD; Ngo LH; Oken E; Hivert MF; Juraschek SP · Hypertension (Dallas, Tex. : 1979) · 2025
Cohort study493 participantsflagCardiovascular Support forscienceVitamin B12
- Vitamin B12 Deficiency, Hyperhomocysteinemia, and Diabetes as Metabolic Determinants of Cardiovascular Risk in Mexican Women.
Ramirez-Villalobos MD; Monterrubio-Flores E; Marquez-Murillo M; Alcalde-Rabanal J; Shamah-Levy T; Perichart-Perera O; Macias-Morales N; Campos-Nonato I · Nutrients · 2025
Cross-sectional study1,197 participantsflagCardiovascular Support forscienceVitamin B12
- Impact of serum vitamin (Vitamin D, Vitamin B12) and trace element (Fe, Zn, Cu) levels on major adverse cardiovascular events and poor prognosis in STEMI patients undergoing primary PCI.
Wang C; Liu D; Tang M; Liu J; Ma Y · Journal of clinical biochemistry and nutrition · 2026
Cohort study202 participantsflagCardiovascular Support forscienceVitamin B12
- Vasoplegic syndrome after cardiovascular surgery: A review of pathophysiology and outcome-oriented therapeutic management.
Datt V; Wadhhwa R; Sharma V; Virmani S; Minhas HS; Malik S · Journal of cardiac surgery · 2021
Systematic reviewflagCardiovascular Support forscienceVitamin B12
- Association between serum pyridoxal 5'-phosphate levels and all-cause, cardiovascular mortality, and cardiovascular disease in adults: a population-based cohort study.
Xuan C; Liu RH; Zhao C; Li J; Zhou TT; Tian QW; He GW · Therapeutic advances in chronic disease · 2024
Cohort studyflagCardiovascular Support forscienceVitamin B6
- Folate and vitamin B6 rapidly normalize endothelial dysfunction in children with type 1 diabetes mellitus.
MacKenzie KE; Wiltshire EJ; Gent R; Hirte C; Piotto L; Couper JJ · Pediatrics · 2006
Randomized trial124 participantsflagCardiovascular Support forscienceVitamin B6
- Pyridoxine improves endothelial function in cardiac transplant recipients.
Miner SE; Cole DE; Evrovski J; Forrest Q; Hutchison S; Holmes K; Ross HJ · The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · 2001
Randomized trial31 participantsflagCardiovascular Support forscienceVitamin B6
- Folate and vitamin B6 from diet and supplements in relation to risk of coronary heart disease among women.
Rimm EB; Willett WC; Hu FB; Sampson L; Colditz GA; Manson JE; Hennekens C; Stampfer MJ · JAMA · 1998
Cohort study80,082 participantsflagCardiovascular Support forscienceVitamin B6
- Efficacy and safety of pyridoxal 5'-phosphate (MC-1) in high-risk patients undergoing coronary artery bypass graft surgery: the MEND-CABG II randomized clinical trial.
MEND-CABG II Investigators; Alexander JH; Emery RW; Carrier M; Ellis SJ; Mehta RH; Hasselblad V; Menasche P; Khalil A; Cote R; Bennett-Guerrero E; Mack MJ; Schuler G; Harrington RA; Tardif JC · JAMA · 2008
Randomized trial3,023 participantsflagCardiovascular Support forscienceVitamin B6
- Supplementation with vitamin E alone is associated with reduced myocardial infarction: a meta-analysis.
Loffredo L; Perri L; Di Castelnuovo A; Iacoviello L; De Gaetano G; Violi F · Nutrition, metabolism, and cardiovascular diseases : NMCD · 2016
Meta-analysis16 studies pooledflagCardiovascular Support forscienceVitamin E
- Vitamin E ameliorates blood cholesterol level and alters gut microbiota composition: A randomized controlled trial.
Chen B; Li Y; Li Z; Hu X; Zhen H; Chen H; Nie C; Hou Y; Zhu S; Xiao L; Li T · Nutrition, metabolism, and cardiovascular diseases : NMCD · 2025
Randomized trial90 participantsflagCardiovascular Support forscienceVitamin E
- Effects of long-term vitamin E supplementation on cardiovascular events and cancer: a randomized controlled trial.
Lonn E; Bosch J; Yusuf S; Sheridan P; Pogue J; Arnold JM; Ross C; Arnold A; Sleight P; Probstfield J; Dagenais GR; HOPE and HOPE-TOO Trial Investigators · JAMA · 2005
Randomized trial9,541 participantsflagCardiovascular Support forscienceVitamin E
- Independent and combined associations of dietary antioxidant exposure with all-cause and cause-specific mortality in the general population.
Liu Z; He Z; Xing Y · Journal of nutritional science · 2026
Cohort study34,955 participantsflagCardiovascular Support forscienceVitamin E
- Tocotrienol rich fraction supplementation improved lipid profile and oxidative status in healthy older adults: A randomized controlled study.
Chin SF; Ibahim J; Makpol S; Abdul Hamid NA; Abdul Latiff A; Zakaria Z; Mazlan M; Mohd Yusof YA; Abdul Karim A; Wan Ngah WZ · Nutrition & metabolism · 2011
Randomized trial62 participantsflagCardiovascular Support forscienceVitamin E
- Vitamin K Intake and Atherosclerotic Cardiovascular Disease in the Danish Diet Cancer and Health Study.
Bellinge JW; Dalgaard F; Murray K; Connolly E; Blekkenhorst LC; Bondonno CP; Lewis JR; Sim M; Croft KD; Gislason G; Torp-Pedersen C; Tjønneland A; Overvad K; Hodgson JM; Schultz C; Bondonno NP · Journal of the American Heart Association · 2021
Cohort study53,372 participantsflagCardiovascular Support forscienceVitamin K
- Menaquinone-7 supplementation improves arterial stiffness in healthy postmenopausal women. A double-blind randomised clinical trial.
Knapen MH; Braam LA; Drummen NE; Bekers O; Hoeks AP; Vermeer C · Thrombosis and haemostasis · 2016
Randomized trial244 participantsflagCardiovascular Support forscienceVitamin K
- Effects of One-Year Menaquinone-7 Supplementation on Vascular Stiffness and Blood Pressure in Post-Menopausal Women.
de Vries F; Bittner R; Maresz K; Machuron F; Gåserød O; Jeanne JF; Schurgers LJ · Nutrients · 2025
Randomized trial165 participantsflagCardiovascular Support forscienceVitamin K
- Dietary Vitamin K1 Intake and Incident Aortic Valve Stenosis.
Schultz CJ; Dalgaard F; Bellinge JW; Murray K; Sim M; Connolly E; Blekkenhorst LC; Bondonno CP; Lewis JR; Gislason GH; Tjønneland A; Overvad K; Hodgson JM; Bondonno NP · Arteriosclerosis, thrombosis, and vascular biology · 2024
Cohort study55,545 participantsflagCardiovascular Support forscienceVitamin K
- Association between vitamin K1 intake and mortality in the Danish Diet, Cancer, and Health cohort.
Palmer CR; Bellinge JW; Dalgaard F; Sim M; Murray K; Connolly E; Blekkenhorst LC; Bondonno CP; Croft KD; Gislason G; Tjønneland A; Overvad K; Schultz C; Lewis JR; Hodgson JM; Bondonno NP · European journal of epidemiology · 2021
Cohort study56,048 participantsflagCardiovascular Support forscienceVitamin K
- Effect of ashwagandha (Withania somnifera) extract with Sominone (Somin-On™) to improve memory in adults with mild cognitive impairment: A randomized, double-blind, placebo-controlled study.
Rai HP; Mishra DN · Journal of psychopharmacology (Oxford, England) · 2025
Randomized trial40 participantsflagCognitive Support forscienceAshwagandha
- Acute and Repeated Ashwagandha Supplementation Improves Markers of Cognitive Function and Mood.
Leonard M; Dickerson B; Estes L; Gonzalez DE; Jenkins V; Johnson S; Xing D; Yoo C; Ko J; Purpura M; Jäger R; Faries M; Kephart W; Sowinski R; Rasmussen CJ; Kreider RB · Nutrients · 2024
Randomized trial59 participantsflagCognitive Support flagEnergy forscienceAshwagandha
- A standardized Ashwagandha root extract alleviates stress, anxiety, and improves quality of life in healthy adults by modulating stress hormones: Results from a randomized, double-blind, placebo-controlled study.
Majeed M; Nagabhushanam K; Mundkur L · Medicine · 2023
Randomized trial54 participantsflagCognitive Support forscienceAshwagandha
- Efficacy and safety of ashwagandha root extract in children and adolescents with mild attention-deficit/hyperactivity disorder: a randomized, double-blind, placebo-controlled trial.
Naik S; Muralidhar G; Rao BS; Agarwal S; Jain M · Journal of medicine and life · 2026
Randomized trial58 participantsflagCognitive Support forscienceAshwagandha
- Efficacy of Withania somnifera supplementation on adult's cognition and mood.
Remenapp A; Coyle K; Orange T; Lynch T; Hooper D; Hooper S; Conway K; Hausenblas HA · Journal of Ayurveda and integrative medicine · 2022
Randomized trial60 participantsflagCognitive Support forscienceAshwagandha
- Cognitive improvement in mild to moderate Alzheimer's dementia after treatment with the acetylcholine precursor choline alfoscerate: a multicenter, double-blind, randomized, placebo-controlled trial.
De Jesus Moreno Moreno M · Clinical therapeutics · 2003
Randomized trial261 participantsflagCognitive Support forscienceCholine
- Association of dietary choline intake with incidence of dementia, Alzheimer disease, and mild cognitive impairment: a large population-based prospective cohort study.
Niu YY; Yan HY; Zhong JF; Diao ZQ; Li J; Li CP; Chen LH; Huang WQ; Xu M; Xu ZT; Liang XF; Li ZH; Liu D · The American journal of clinical nutrition · 2025
Cohort study125,594 participantsflagCognitive Support forscienceCholine
- Choline intake during pregnancy and child cognition at age 7 years.
Boeke CE; Gillman MW; Hughes MD; Rifas-Shiman SL; Villamor E; Oken E · American journal of epidemiology · 2013
Cohort study895 participantsflagCognitive Support forscienceCholine
- Effects of choline alfoscerate on cognitive function and quality of life in type 2 diabetes: A double-blind, randomized, placebo-controlled trial.
Sohn M; Park YH; Lim S · Diabetes, obesity & metabolism · 2025
Randomized trial36 participantsflagCognitive Support forscienceCholine
- Maternal choline supplementation mitigates alcohol exposure effects on neonatal brain volumes.
Warton FL; Molteno CD; Warton CMR; Wintermark P; Lindinger NM; Dodge NC; Zöllei L; van der Kouwe AJW; Carter RC; Jacobson JL; Jacobson SW; Meintjes EM · Alcoholism, clinical and experimental research · 2022
Randomized trial52 participantsflagCognitive Support forscienceCholine
- Effects of 6-Month Folic Acid Supplementation on Cognitive Function and Blood Biomarkers in Mild Cognitive Impairment: A Randomized Controlled Trial in China.
Ma F; Wu T; Zhao J; Han F; Marseglia A; Liu H; Huang G · The journals of gerontology. Series A, Biological sciences and medical sciences · 2017
Randomized trial180 participantsflagCognitive Support forscienceFolate
- Serum folate and B12 levels in association with cognitive impairment among seniors: results from the VELESTINO study in Greece and meta-analysis.
Michelakos T; Kousoulis AA; Katsiardanis K; Dessypris N; Anastasiou A; Katsiardani KP; Kanavidis P; Stefanadis C; Papadopoulos FC; Petridou ET · Journal of aging and health · 2013
Meta-analysis8,122 participants9 studies pooledflagCognitive Support forscienceFolate
- B vitamins and prevention of cognitive decline and incident dementia: a systematic review and meta-analysis.
Wang Z; Zhu W; Xing Y; Jia J; Tang Y · Nutrition reviews · 2022
Meta-analysis46,175 participants95 studies pooledflagCognitive Support forscienceFolate
- Homocysteine and folate as risk factors for dementia and Alzheimer disease.
Ravaglia G; Forti P; Maioli F; Martelli M; Servadei L; Brunetti N; Porcellini E; Licastro F · The American journal of clinical nutrition · 2005
Cohort study816 participantsflagCognitive Support forscienceFolate
- Folate mediates cognitive impairment of aged people with periodontitis.
Liu F; Liu Y; Feng Y; Zhao J; Wang M; Ye M; Zhang Y; Gan X; Pan Q; Shen J · Nutritional neuroscience · 2025
Cross-sectional study1,966 participantsflagCognitive Support forscienceFolate
- Magnesium sulphate for women at risk of preterm birth for neuroprotection of the fetus.
Doyle LW; Crowther CA; Middleton P; Marret S; Rouse D · The Cochrane database of systematic reviews · 2009
Meta-analysis6,145 participants5 studies pooledflagCognitive Support forscienceMagnesium
- Effects of magnesium valproate adjuvant therapy on patients with dementia: A systematic review and meta-analysis.
Zhang C; Sun L; Sun H · Medicine · 2022
Meta-analysis1,899 participants22 studies pooledflagCognitive Support forscienceMagnesium
- Effects of magnesium supplementation on serum brain-derived neurotrophic factor levels and cognitive function in patients undergoing fluoxetine therapy for depression.
Noor NJ; Syamsuddin S; Liaury K; Tawali S; Idris I; Azis I; Lisal ST · East Asian archives of psychiatry : official journal of the Hong Kong College of Psychiatrists = Dong Ya jing shen ke xue zhi : Xianggang jing shen ke yi xue yuan qi kan · 2026
Randomized trial40 participantsflagCognitive Support forscienceMagnesium
- Magnesium-L-threonate improves sleep quality and daytime functioning in adults with self-reported sleep problems: A randomized controlled trial.
Hausenblas HA; Lynch T; Hooper S; Shrestha A; Rosendale D; Gu J · Sleep medicine: X · 2025
Randomized trial80 participantsflagCognitive Support flagEnergy forscienceMagnesium
- Could intraoperative magnesium sulphate protect against postoperative cognitive dysfunction?
Hassan WF; Tawfik MH; Nabil TM; Abd Elkareem RM · Minerva anestesiologica · 2021
Randomized trial80 participantsflagCognitive Support forscienceMagnesium
- Evidence-based efficacy of adaptogens in fatigue, and molecular mechanisms related to their stress-protective activity.
Panossian A; Wikman G · Current clinical pharmacology · 2009
Narrative reviewflagCognitive Support forscienceRhodiola
- Effects of a Rhodiola rosea extract on mental resource allocation and attention: An event-related potential dual task study.
Koop T; Dienel A; Heldmann M; Münte TF · Phytotherapy research : PTR · 2021
Single-arm trial50 participantsflagCognitive Support forscienceRhodiola
- Central additive effect of Ginkgo biloba and Rhodiola rosea on psychomotor vigilance task and short-term working memory accuracy.
Al-Kuraishy HM · Journal of intercultural ethnopharmacology · 2016
Clinical trial112 participantsflagCognitive Support forscienceRhodiola
- Clinical evidence for the adaptogenic effects of Withania somnifera and Rhodiola rosea - A systematic review with molecular interpretation of psychometric outcomes.
Łuszczak J; Kocki J · Annals of agricultural and environmental medicine : AAEM · 2026
Systematic review19 studies pooledflagCognitive Support flagStress Relief forscienceRhodiola
- A randomised, double-blind, placebo-controlled, parallel-group study of the standardised extract shr-5 of the roots of Rhodiola rosea in the treatment of subjects with stress-related fatigue.
Olsson EM; von Schéele B; Panossian AG · Planta medica · 2009
Randomized trial60 participantsflagCognitive Support forscienceRhodiola
- Safety and Efficacy of High-Dose Vitamin B6 as an Adjunctive Treatment for Antipsychotic-Induced Hyperprolactinemia in Male Patients With Treatment-Resistant Schizophrenia.
Zhuo C; Xu Y; Wang H; Fang T; Chen J; Zhou C; Li Q; Liu J; Xu S; Yao C; Yang W; Yang A; Li B; Chen Y; Tian H; Lin C · Frontiers in psychiatry · 2021
Randomized trial200 participantsflagCognitive Support forscienceVitamin B6
- Associations between dietary B vitamin intakes and cognitive function among elderly individuals: An observational study.
Chen Q; Huang J; Shi X; Peng Y; Chen A; Huang L; Zhang Y; Chen X · Nutrition (Burbank, Los Angeles County, Calif.) · 2025
Cross-sectional study2,716 participantsflagCognitive Support forscienceVitamin B6
- Lower Plasma Vitamin B-6 is Associated with 2-Year Cognitive Decline in the Boston Puerto Rican Health Study.
Palacios N; Scott T; Sahasrabudhe N; Gao X; Tucker KL · The Journal of nutrition · 2020
Cohort study949 participantsflagCognitive Support forscienceVitamin B6
- Lower water-soluble vitamins and higher homocysteine are associated with neurodegenerative diseases.
Zhang C; Hu Y; Cao X; Deng Y; Wang Y; Guan M; Wu X; Jiang H · Scientific reports · 2025
Cohort study926 participantsflagCognitive Support forscienceVitamin B6
- Associations of one-carbon metabolism, related B-vitamins and ApoE genotype with cognitive function in older adults: identification of a novel gene-nutrient interaction.
Gordon S; Hoey L; McNulty H; Keenan J; Pangilinan F; Brody LC; Ward M; Strain JJ; McAnena L; McCann A; Molloy AM; Cunningham C; McCarroll K; Hughes CF · BMC medicine · 2025
Observational study4,553 participantsflagCognitive Support forscienceVitamin B6
- Choline and contribution to normal liver function of the foetus and exclusively breastfed infants: evaluation of a health claim pursuant to Article 14 of Regulation (EC) No 1924/2006.
EFSA Panel on Nutrition, Novel Foods and Food allergens (NDA); Turck D; Bohn T; Castenmiller J; De Henauw S; Hirsch-Ernst KI; Knutsen HK; Maciuk A; Mangelsdorf I; McArdle HJ; Naska A; Pentieva K; Thies F; Tsabouri S; Vinceti M; Bresson JL; Fiolet T; Siani A · EFSA journal. European Food Safety Authority · 2024
Guideline / consensusflagDetoxification forscienceCholine
- Adiposity May Moderate the Link Between Choline Intake and Non-alcoholic Fatty Liver Disease.
Mazidi M; Katsiki N; Mikhailidis DP; Banach M · Journal of the American College of Nutrition · 2020
Cross-sectional study20,643 participantsflagDetoxification forscienceCholine
- Choline and Choline-Related Metabolites in Pediatric Short Bowel Syndrome.
Hilberath J; Shunova A; Heister L; Poets CF; Bernhard W · Nutrients · 2026
Observational study80 participantsflagDetoxification forscienceCholine
- Choline Supplementation in Cystic Fibrosis-The Metabolic and Clinical Impact.
Bernhard W; Lange R; Graepler-Mainka U; Engel C; Machann J; Hund V; Shunova A; Hector A; Riethmüller J · Nutrients · 2019
Single-arm trial10 participantsflagDetoxification forscienceCholine
- 1H MR Spectroscopy at 3T for Hepatic Choline Quantification in Healthy Young Women: A Translational Imaging Study with Dietary Correlation.
Hawesa H; Alghamdi R; Allam H; Alfaifi B; Alrabiah N; Alghumaiz M; Shanawani M; Alshegri H; Hassan MG · Current medical imaging · 2026
Cohort study88 participantsflagDetoxification forscienceCholine
- Comparison of efficacy of folic acid and silymarin in the management of antiepileptic drug induced liver injury: a randomized clinical trial.
Asgarshirazi M; Shariat M; Sheikh M · Hepatobiliary & pancreatic diseases international : HBPD INT · 2018
Randomized trial55 participantsflagDetoxification forscienceFolate
- Homocysteine, folate, and nonalcoholic fatty liver disease: a systematic review with meta-analysis and Mendelian randomization investigation.
Yuan S; Chen J; Dan L; Xie Y; Sun Y; Li X; Larsson SC · The American journal of clinical nutrition · 2022
Meta-analysis30,368 participants22 studies pooledflagDetoxification forscienceFolate
- Serum folate levels and urinary arsenic methylation profiles in the US population: NHANES, 2003-2012.
Zhang X; Xu X; Zhong Y; Power MC; Taylor BD; Carrillo G · Journal of exposure science & environmental epidemiology · 2020
Cross-sectional study11,016 participantsflagDetoxification forscienceFolate
- Association between serum folate levels and blood concentrations of cadmium and lead in US adults.
Wu Z; Hu H; Wang C; Wu J; Xiong Y; Fu Y; Cheng X; Su H; Li P · Environmental science and pollution research international · 2022
Cross-sectional study15,501 participantsflagDetoxification forscienceFolate
- Effects of Folic Acid Supplementation on Liver Enzymes, Lipid Profile, and Insulin Resistance in Patients with Non-Alcoholic Fatty Liver Disease: A Randomized Controlled Trial.
Molaqanbari MR; Zarringol S; Talari HR; Taghizadeh M; Bahmani F; Mohtashamian A; Ebrahimzadeh A; Sharifi N · Advanced biomedical research · 2023
Randomized trial66 participantsflagDetoxification forscienceFolate
- Oral magnesium supplementation improves metabolic variables and muscle strength in alcoholics.
Gullestad L; Dolva LO; Søyland E; Manger AT; Falch D; Kjekshus J · Alcoholism, clinical and experimental research · 1992
Randomized trial49 participantsflagDetoxification forscienceMagnesium
- Magnesium Sulfate Administration in Moderate Coronary Artery Disease Patients Improves Atherosclerotic Risk Factors: A Double-Blind Clinical Trial Study.
Farshidi H; Sobhani AR; Eslami M; Azarkish F; Eftekhar E; Keshavarz M; Soltani N · Journal of cardiovascular pharmacology · 2021
Randomized trialflagDetoxification forscienceMagnesium
- Effects of Synbiotic Food Consumption on Serum Minerals, Liver Enzymes, and Blood Pressure in Patients with Type 2 Diabetes: A Double-blind Randomized Cross-over Controlled Clinical Trial.
Asemi Z; Aarabi MH; Hajijafari M; Alizadeh SA; Razzaghi R; Mazoochi M; Esmaillzadeh A · International journal of preventive medicine · 2020
Randomized trialflagDetoxification forscienceMagnesium
- Clinical experience with 781 cases of alcoholism evaluated and treated on an inpatient basis by various methods.
Daus AT; Freeman WM; Wilson J; Aponte C · The International journal of the addictions · 1985
Observational study781 participantsflagDetoxification forscienceMagnesium
- Ionized hypomagnesemia in patients undergoing orthotopic liver transplantation: a complication of citrate intoxication.
Scott VL; De Wolf AM; Kang Y; Altura BT; Virji MA; Cook DR; Altura BM · Liver transplantation and surgery : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society · 1997
Single-arm trialflagDetoxification forscienceMagnesium
- Human molybdenum exposure risk in industrial regions of China: New critical effect indicators and reference dose.
Kuang HX; Li MY; Zeng XW; Chen D; Zhou Y; Zheng T; Xiang MD; Wu QZ; Chen XC; Dong GH; Yu YJ · Ecotoxicology and environmental safety · 2024
Cross-sectional study2,267 participantsflagDetoxification forscienceMolybdenum
- Supplementation with selenium can influence nausea, fatigue, physical, renal, and liver function of children and adolescents with cancer.
Vieira ML; Fonseca FL; Costa LG; Beltrame RL; Chaves CM; Cartum J; Alves SI; Azzalis LA; Junqueira VB; Pereria EC; Rocha KC · Journal of medicinal food · 2015
Randomized trialflagDetoxification forscienceSelenium
- [Selenium and oxidative stress in cancer patients].
Gorozhanskaia ÉG; Sviridova SP; Dobrovol'skaia MM; Zybrikhina GN; Kashnia ShR · Biomeditsinskaia khimiia · 2014
Single-arm trial40 participantsflagDetoxification forscienceSelenium
- Comprehensive Insights into the Health Effects of Selenium Exposure and Supplementation Among the Chinese Community Middle-Aged and Elderly: a Combined Retrospective Cohort Study and Intervention Study.
Li C; Peng X; Zheng J; Shi K; Qin L; Yang Q; Wang Z; Liu Y; Huang L · Biological trace element research · 2024
Other40 participantsflagDetoxification forscienceSelenium
- Heavy metals and metalloids exposure and liver function in Chinese adults - A nationally representative cross-sectional study.
Wang S; Lyu Y; Ji S; Liu N; Wu B; Zhao F; Li Z; Qu Y; Zhu Y; Xie L; Li Y; Zhang Z; Song H; Hu X; Qiu Y; Zheng X; Zhang W; Yang Y; Li F; Cai J; Zhu Y; Cao Z; Tan F; Shi X · Environmental research · 2024
Cross-sectional study9,445 participantsflagDetoxification forscienceSelenium
- Selenium-Biofortified Strawberries Improve Glucose Homeostasis and Hepatic Function: A 30-Day Randomized Controlled Trial in Healthy Adults.
Vasto S; Di Rosa L; Ferrantelli V; Fiore AS; Giordano CP; Cannizzaro A; Sabatino L; Macaluso A; Caldarella R; Caldara GF; Baldassano S · Nutrients · 2026
Randomized trial35 participantsflagDetoxification forscienceSelenium
- Antidotes for acute cyanide poisoning.
Borron SW; Baud FJ · Current pharmaceutical biotechnology · 2013
Narrative reviewflagDetoxification forscienceVitamin B12
- Prospective study of hydroxocobalamin for acute cyanide poisoning in smoke inhalation.
Borron SW; Baud FJ; Barriot P; Imbert M; Bismuth C · Annals of emergency medicine · 2007
Case series69 participantsflagDetoxification forscienceVitamin B12
- Comment on "Rapid visual detection of blood cyanide" by C. Männel-Croisé and F. Zelder, Analytical Methods, 2012, 4, 2632.
Kadjo AF; Dasgupta PK; Boss GR · Analytical methods : advancing methods and applications · 2023
Editorial / commentaryflagDetoxification forscienceVitamin B12
- [Acute intoxication in adults - what you should know].
Zilker T · Deutsche medizinische Wochenschrift (1946) · 2014
Narrative reviewflagDetoxification forscienceVitamin B12
- Investigating vitamin B12 levels in children with obesity: the role of metformin.
Iwańska A; Goncerz D; Ahmed M; Aoun R; Kozioł-Kozakowska A; Szczudlik E; Stępniewska A; Wójcik M; Starzyk JB · European journal of pediatrics · 2026
Observational study500 participantsflagDetoxification forscienceVitamin B12
- Vitamin C supplementation ameliorates liver function profile and antiviral treatment response in Hepatitis C patients.
Nayila I; Javed MS; Khan MA; Hussain G; Raza Naqvi SA; Ali S; Jabeen Z; Shahnawaz S; Akram R; Iman T; Hassan Dogar MZ; Malik SA · Pakistan journal of pharmaceutical sciences · 2022
Non-randomized trial200 participantsflagDetoxification forscienceVitamin C
- Effect of ascorbic acid-rich diet on in vivo-induced oxidative stress.
Alleva R; Di Donato F; Strafella E; Staffolani S; Nocchi L; Borghi B; Pignotti E; Santarelli L; Tomasetti M · The British journal of nutrition · 2012
Non-randomized trial46 participantsflagDetoxification forscienceVitamin C
- Dietary Vitamin C Intake Is Associated With Improved Liver Function and Glucose Metabolism in Chinese Adults.
Luo X; Zhang W; He Z; Yang H; Gao J; Wu P; Ma ZF · Frontiers in nutrition · 2022
Observational study8,307 participantsflagDetoxification forscienceVitamin C
- Plasma ascorbate deficiency is associated with impaired reduction of sulfamethoxazole-nitroso in HIV infection.
Trepanier LA; Yoder AR; Bajad S; Beckwith MD; Bellehumeur JL; Graziano FM · Journal of acquired immune deficiency syndromes (1999) · 2005
Observational studyflagDetoxification forscienceVitamin C
- Roles of endogenous ascorbate and glutathione in the cellular reduction and cytotoxicity of sulfamethoxazole-nitroso.
Lavergne SN; Kurian JR; Bajad SU; Maki JE; Yoder AR; Guzinski MV; Graziano FM; Trepanier LA · Toxicology · 2006
Clinical trial53 participantsflagDetoxification forscienceVitamin C
- [Therapy of Wilson disease].
Smolarek C; Stremmel W · Zeitschrift fur Gastroenterologie · 1999
Narrative reviewflagDetoxification forscienceZinc
- Efficacy of Zinc Supplement in Minimal hepatic Encephalopathy: A prospective, Randomized Controlled Study (Zinc-MHE Trial).
Janyajirawong R; Vilaichone RK; Sethasine S · Asian Pacific journal of cancer prevention : APJCP · 2021
Randomized trial69 participantsflagDetoxification forscienceZinc
- Effect of zinc on liver cirrhosis with hyperammonemia: a preliminary randomized, placebo-controlled double-blind trial.
Katayama K; Saito M; Kawaguchi T; Endo R; Sawara K; Nishiguchi S; Kato A; Kohgo H; Suzuki K; Sakaida I; Ueno Y; Habu D; Ito T; Moriwaki H; Suzuki K · Nutrition (Burbank, Los Angeles County, Calif.) · 2015
Randomized trial18 participantsflagDetoxification forscienceZinc
- Effects of low dose zinc supplementation on biochemical markers in non-alcoholic cirrhosis: a randomized clinical trial.
Somi MH; Rezaeifar P; Ostad Rahimi A; Moshrefi B · Archives of Iranian medicine · 2012
Randomized trial60 participantsflagDetoxification forscienceZinc
- Correlation of Serum Zinc Levels with Hepatic Encephalopathy Severity in Patients with Decompensated Liver Cirrhosis: A Prospective Observational Study from Egypt.
Semeya AA; Elgamal R; Othman AAA · Biological trace element research · 2025
Observational study200 participantsflagDetoxification forscienceZinc
- Efficacy of oral magnesium therapy in the treatment of chronic constipation in spastic cerebral palsy children: a randomized controlled trial.
Hassanein SMA; Deifallah SM; Bastawy HA · World journal of pediatrics : WJP · 2021
Randomized trial100 participantsflagDigestive Health forscienceMagnesium
- Ca:Mg ratio, medium-chain fatty acids, and the gut microbiome.
Fan L; Zhu X; Sun S; Yu C; Huang X; Ness R; Dugan LL; Shu L; Seidner DL; Murff HJ; Fodor AA; Azcarate-Peril MA; Shrubsole MJ; Dai Q · Clinical nutrition (Edinburgh, Scotland) · 2022
Randomized trial240 participantsflagDigestive Health forscienceMagnesium
- The Magnesium-Rich Formula for Functional Constipation in Infants: a Randomized Comparator-Controlled Study.
Benninga MA; MENA Infant Constipation Study Group; Vandenplas Y · Pediatric gastroenterology, hepatology & nutrition · 2022
Randomized trial286 participantsflagDigestive Health forscienceMagnesium
- A Randomized Double-blind Placebo-controlled Trial on the Effect of Magnesium Oxide in Patients With Chronic Constipation.
Mori S; Tomita T; Fujimura K; Asano H; Ogawa T; Yamasaki T; Kondo T; Kono T; Tozawa K; Oshima T; Fukui H; Kimura T; Watari J; Miwa H · Journal of neurogastroenterology and motility · 2022
Randomized trial34 participantsflagDigestive Health forscienceMagnesium
- Magnesium treatment increases gut microbiome synthesizing vitamin D and inhibiting colorectal cancer: results from a double-blind precision-based randomized placebo-controlled trial.
Sun E; Zhu X; Ness RM; Murff HJ; Sun S; Yu C; Fan L; Azcarate-Peril MA; Shrubsole MJ; Dai Q · The American journal of clinical nutrition · 2025
Randomized trial240 participantsflagDigestive Health forscienceMagnesium
- Oral zinc supplementation for the treatment of acute diarrhea in children: a systematic review and meta-analysis.
Lamberti LM; Walker CL; Chan KY; Jian WY; Black RE · Nutrients · 2014
Meta-analysis18,822 participants104 studies pooledflagDigestive Health forscienceZinc
- Zinc with oral rehydration therapy reduces stool output and duration of diarrhea in hospitalized children: a randomized controlled trial.
Bhatnagar S; Bahl R; Sharma PK; Kumar GT; Saxena SK; Bhan MK · Journal of pediatric gastroenterology and nutrition · 2004
Randomized trial287 participantsflagDigestive Health forscienceZinc
- Lower-Dose Zinc for Childhood Diarrhea - A Randomized, Multicenter Trial.
Dhingra U; Kisenge R; Sudfeld CR; Dhingra P; Somji S; Dutta A; Bakari M; Deb S; Devi P; Liu E; Chauhan A; Kumar J; Semwal OP; Aboud S; Bahl R; Ashorn P; Simon J; Duggan CP; Sazawal S; Manji K · The New England journal of medicine · 2020
Randomized trial4,500 participantsflagDigestive Health forscienceZinc
- Zinc supplementation in young children with acute diarrhea in India.
Sazawal S; Black RE; Bhan MK; Bhandari N; Sinha A; Jalla S · The New England journal of medicine · 1995
Randomized trial937 participantsflagDigestive Health flagGeneral Health forscienceZinc
- Short-course prophylactic zinc supplementation for diarrhea morbidity in infants of 6 to 11 months.
Malik A; Taneja DK; Devasenapathy N; Rajeshwari K · Pediatrics · 2013
Randomized trial272 participantsflagDigestive Health forscienceZinc
- Effects of multi-herb and ashwagandha root formulas on stress modulation: a randomized, double-blind, placebo-controlled clinical study.
McKinney E; Stewart J; Kewalramani R; Singh S · Trials · 2026
Randomized trial186 participantsflagEnergy forscienceAshwagandha
- Efficacy and Safety of Low-Dose Ashwagandha Supplementation on Exercise Endurance: A Randomized, Placebo-Controlled, Double-Blind, Clinical Trial.
Prajapati H; Satia M; Shah D; Basera I; Shah T · Phytotherapy research : PTR · 2026
Randomized trialflagEnergy forscienceAshwagandha
- Enhancing healthspan with Ashwagandha (Withania somnifera): a comprehensive review of its multifaceted geroprotective benefits.
Vittal M; Vinciguerra M · Biogerontology · 2025
Narrative reviewflagEnergy forscienceAshwagandha
- Safety and Efficacy of Ashwagandha Root Extract on Cognition, Energy and Mood Problems in Adults: Prospective, Randomized, Placebo-Controlled Study.
Kale S; Lopresti A; Suri R; Garg N; Langade D · Journal of psychoactive drugs · 2026
Randomized trial120 participantsflagEnergy forscienceAshwagandha
- Total magnesium intake and risk of frailty in older women.
Struijk EA; Fung TT; Bischoff-Ferrari HA; Willett WC; Lopez-Garcia E · Journal of cachexia, sarcopenia and muscle · 2024
Cohort study81,524 participantsflagEnergy forscienceMagnesium
- Red blood cell magnesium and chronic fatigue syndrome.
Cox IM; Campbell MJ; Dowson D · Lancet (London, England) · 1991
Randomized trial32 participantsflagEnergy forscienceMagnesium
- Exercise, magnesium and immune function.
Laires MJ; Monteiro C · Magnesium research · 2008
Narrative reviewflagEnergy forscienceMagnesium
- The Effect of Short-Term Rhodiola rosea Supplementation on Simulated Game Time, Perceived Fatigue, and Performance in Basketball Players.
Wang J; Zhao H; Yu L; Zhao K; Jiang W; Liu S; Dai J; Xu L; Sun P; Yun H; Liu C · Nutrients · 2025
Randomized trial48 participantsflagEnergy forscienceRhodiola
- Effects of Rhodiola rosea on Physical and Decision-Making Performance in Football Players: A Randomised Controlled Trial.
Dou Y; Wang Y; Zhang W; Jiang Y; Zhang J; Yang T; Han Z; Li Y; Liu C; Ren D · Nutrients · 2026
Randomized trial24 participantsflagEnergy forscienceRhodiola
- Combined Effects of Rhodiola Rosea and Caffeine Supplementation on Straight Punch Explosive Power in Untrained and Trained Boxing Volunteers: A Synergistic Approach.
Tao B; Sun H; Li H; Xu Z; Xu Y; Chen L; Ma C; Zhang X; Yu L; Bao S; Liu C · Metabolites · 2025
Randomized trial96 participantsflagEnergy forscienceRhodiola
- Rhodiola rosea in Subjects with Prolonged or Chronic Fatigue Symptoms: Results of an Open-Label Clinical Trial.
Lekomtseva Y; Zhukova I; Wacker A · Complementary medicine research · 2019
Single-arm trial100 participantsflagEnergy flagStress Relief forscienceRhodiola
- Combined Rhodiola rosea and eccentric training boost endurance performance and lower-limb reactive strength in recreationally active women.
Wang IL; Su Y; Zhang L; Tang M; Chen YM · Frontiers in physiology · 2025
Randomized trial30 participantsflagEnergy forscienceRhodiola
- A randomized, double blind, placebo controlled study to evaluate the effects of ashwagandha (Withania somnifera) extract on sleep quality in healthy adults.
Deshpande A; Irani N; Balkrishnan R; Benny IR · Sleep medicine · 2021
Randomized trial150 participantsflagGeneral Health forscienceAshwagandha
- Effects of Ashwagandha ( Withania somnifera) standardized root extract on physical endurance and VO 2max in healthy adults performing resistance training: An eight-week, prospective, randomized, double-blind, placebo-controlled study.
Verma N; Gupta SK; Patil S; Tiwari S; Mishra AK · F1000Research · 2024
Randomized trial80 participantsflagGeneral Health forscienceAshwagandha
- Efficacy of Ashwagandha (Withania somnifera [L.] Dunal) in improving cardiorespiratory endurance in healthy athletic adults.
Choudhary B; Shetty A; Langade DG · Ayu · 2016
Randomized trial50 participantsflagGeneral Health forscienceAshwagandha
- Withania somnifera (L.) Dunal as Add-On Therapy for COPD Patients: A Randomized, Placebo-Controlled, Double-Blind Study.
Singh P; Salman KA; Shameem M; Warsi MS · Frontiers in pharmacology · 2022
Randomized trial150 participantsflagGeneral Health forscienceAshwagandha
- Effect of Ashwagandha (Withania somnifera) extract on sleep: A systematic review and meta-analysis.
Cheah KL; Norhayati MN; Husniati Yaacob L; Abdul Rahman R · PloS one · 2021
Meta-analysis400 participants5 studies pooledflagGeneral Health forscienceAshwagandha
- Intakes of Folate, Vitamin B6, and Vitamin B12 in Relation to All-Cause and Cause-Specific Mortality: A National Population-Based Cohort.
Bo Y; Xu H; Zhang H; Zhang J; Wan Z; Zhao X; Yu Z · Nutrients · 2022
Cohort study55,569 participantsflagGeneral Health forscienceFolate
- The responsiveness of plasma homocysteine to small increases in dietary folic acid: a primary care study.
Schorah CJ; Devitt H; Lucock M; Dowell AC · European journal of clinical nutrition · 1998
Randomized trial119 participantsflagGeneral Health forscienceFolate
- Associations of Serum Folate and Homocysteine Concentrations with All-Cause, Cardiovascular Disease, and Cancer Mortality in Men and Women in Korea: the Cardiovascular Disease Association Study.
Song S; Song BM; Park HY · The Journal of nutrition · 2023
Cohort study21,260 participantsflagGeneral Health forscienceFolate
- The concept of folic acid supplementation and its role in prevention of neural tube defect among pregnant women: PRISMA.
Seyoum Tola F · Medicine · 2024
Systematic reviewflagGeneral Health forscienceFolate
- Systematic review of adverse health outcomes associated with high serum or red blood cell folate concentrations.
Colapinto CK; O'Connor DL; Sampson M; Williams B; Tremblay MS · Journal of public health (Oxford, England) · 2017
Systematic review71,847 participants46 studies pooledflagGeneral Health forscienceFolate
- Perioperative systemic magnesium to minimize postoperative pain: a meta-analysis of randomized controlled trials.
De Oliveira GS; Castro-Alves LJ; Khan JH; McCarthy RJ · Anesthesiology · 2013
Meta-analysis1,257 participants20 studies pooledflagGeneral Health forscienceMagnesium
- Long-term outcome after intravenous magnesium sulphate in suspected acute myocardial infarction: the second Leicester Intravenous Magnesium Intervention Trial (LIMIT-2).
Woods KL; Fletcher S · Lancet (London, England) · 1994
Randomized trial2,316 participantsflagGeneral Health forscienceMagnesium
- Association of magnesium sulfate use with mortality in critically ill patients with sepsis: a retrospective propensity score-matched cohort study.
Gu WJ; Duan XJ; Liu XZ; Cen Y; Tao LY; Lyu J; Yin HY · British journal of anaesthesia · 2023
Cohort study10,999 participantsflagGeneral Health forscienceMagnesium
- Hypomagnesemia and Mortality in Incident Hemodialysis Patients.
Li L; Streja E; Rhee CM; Mehrotra R; Soohoo M; Brunelli SM; Kovesdy CP; Kalantar-Zadeh K · American journal of kidney diseases : the official journal of the National Kidney Foundation · 2016
Cohort study9,359 participantsflagGeneral Health forscienceMagnesium
- The effects of magnesium supplementation on abnormal uterine bleeding, alopecia, quality of life, and acne in women with polycystic ovary syndrome: a randomized clinical trial.
Jaripur M; Ghasemi-Tehrani H; Askari G; Gholizadeh-Moghaddam M; Clark CCT; Rouhani MH · Reproductive biology and endocrinology : RB&E · 2022
Randomized trial64 participantsflagGeneral Health forscienceMagnesium
- Dietary Antioxidants, Circulating Antioxidant Concentrations, Total Antioxidant Capacity, and Risk of All-Cause Mortality: A Systematic Review and Dose-Response Meta-Analysis of Prospective Observational Studies.
Jayedi A; Rashidy-Pour A; Parohan M; Zargar MS; Shab-Bidar S · Advances in nutrition (Bethesda, Md.) · 2019
Meta-analysis507,251 participants41 studies pooledflagGeneral Health forscienceSelenium
- The efficacy and safety of selenium supplementation versus placebo in the treatment of Graves' orbitopathy: A systematic review and meta-analysis of randomised controlled trials.
Sharabati I; Qafesha RM; Hindawi MD; Amro S; Ayesh BM · Clinical endocrinology · 2024
Meta-analysis4 studies pooledflagGeneral Health flagVision Support forscienceSelenium
- Associations of plasma metal concentrations with the risks of all-cause and cardiovascular disease mortality in Chinese adults.
Shi L; Yuan Y; Xiao Y; Long P; Li W; Yu Y; Liu Y; Liu K; Wang H; Zhou L; Yang H; Li X; He M; Wu T · Environment international · 2021
Cohort study6,155 participantsflagGeneral Health forscienceSelenium
- Updates on clinical studies of selenium supplementation in radiotherapy.
Puspitasari IM; Abdulah R; Yamazaki C; Kameo S; Nakano T; Koyama H · Radiation oncology (London, England) · 2015
Systematic review16 studies pooledflagGeneral Health forscienceSelenium
- Oral Vitamin B12 versus Placebo for the Prevention of Chemotherapy-Induced Peripheral Neuropathy in Gynecological Cancer Patients: A Randomized, Double-Blind, Placebo-Controlled Trial.
Insin P; Chaiwongsa T; Prueksaritanond N · Asian Pacific journal of cancer prevention : APJCP · 2026
Randomized trial40 participantsflagGeneral Health forscienceVitamin B12
- Vitamin B12 Supplementation in Diabetic Neuropathy: A 1-Year, Randomized, Double-Blind, Placebo-Controlled Trial.
Didangelos T; Karlafti E; Kotzakioulafi E; Margariti E; Giannoulaki P; Batanis G; Tesfaye S; Kantartzis K · Nutrients · 2021
Randomized trial90 participantsflagGeneral Health forscienceVitamin B12
- A single-center randomized controlled trial of local methylcobalamin injection for subacute herpetic neuralgia.
Xu G; Lv ZW; Feng Y; Tang WZ; Xu GX · Pain medicine (Malden, Mass.) · 2014
Randomized trial98 participantsflagGeneral Health forscienceVitamin B12
- Local Injection of Methylcobalamin Combined with Lidocaine for Acute Herpetic Neuralgia.
Xǔ G; Xu S; Tang WZ; Xú G; Cheng C; Xu J · Pain medicine (Malden, Mass.) · 2017
Randomized trial204 participantsflagGeneral Health forscienceVitamin B12
- The Effect of Vitamin B12 and Folic Acid Supplementation on Serum Homocysteine, Anemia Status and Quality of Life of Patients with Multiple Sclerosis.
Nozari E; Ghavamzadeh S; Razazian N · Clinical nutrition research · 2022
Clinical trial50 participantsflagGeneral Health forscienceVitamin B12
- Dietary intake and blood concentrations of antioxidants and the risk of cardiovascular disease, total cancer, and all-cause mortality: a systematic review and dose-response meta-analysis of prospective studies.
Aune D; Keum N; Giovannucci E; Fadnes LT; Boffetta P; Greenwood DC; Tonstad S; Vatten LJ; Riboli E; Norat T · The American journal of clinical nutrition · 2019
Meta-analysis69 studies pooledflagGeneral Health forscienceVitamin C
- Scientific Opinion on the substantiation of a health claim related to vitamin C and increasing non haem iron absorption pursuant to Article 14 of Regulation (EC) No 1924/2006.
EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) · EFSA journal. European Food Safety Authority · 2026
Guideline / consensusflagGeneral Health forscienceVitamin C
- Vitamin C Depletion and All-Cause Mortality in Renal Transplant Recipients.
Sotomayor CG; Eisenga MF; Gomes Neto AW; Ozyilmaz A; Gans ROB; Jong WHA; Zelle DM; Berger SP; Gaillard CAJM; Navis GJ; Bakker SJ · Nutrients · 2018
Cohort study598 participantsflagGeneral Health forscienceVitamin C
- Associations of Serum Biomarkers of Fruit and Vegetable Intake With the Risk of Cause-Specific Mortality and All-Cause Mortality: A National Prospective Cohort Study.
Pu L; Zhang R; Wang X; Zhao T; Sun H; Han L · Frontiers in nutrition · 2022
Cohort study12,530 participantsflagGeneral Health forscienceVitamin C
- Relation between plasma ascorbic acid and mortality in men and women in EPIC-Norfolk prospective study: a prospective population study. European Prospective Investigation into Cancer and Nutrition.
Khaw KT; Bingham S; Welch A; Luben R; Wareham N; Oakes S; Day N · Lancet (London, England) · 2001
Cohort study19,496 participantsflagGeneral Health forscienceVitamin C
- Effectiveness of sodium bicarbonate and zinc chloride mouthwashes in the treatment of oral mucositis and quality of life in patients with cancer under chemotherapy.
Mohammadi F; Oshvandi K; Kamallan SR; Khazaei S; Ranjbar H; Ahmadi-Motamayel F; Gillespie M; Jenabi E; Vafaei SY · Nursing open · 2022
Randomized trial144 participantsflagGeneral Health forscienceZinc
- Associations of mortality with ocular disorders and an intervention of high-dose antioxidants and zinc in the Age-Related Eye Disease Study: AREDS Report No. 13.
Clemons TE; Kurinij N; Sperduto RD; AREDS Research Group · Archives of ophthalmology (Chicago, Ill. : 1960) · 2004
Randomized trial4,753 participantsflagGeneral Health forscienceZinc
- Effects of zinc and probiotic co-supplementation on inflammation, gastrointestinal symptoms, quality of life, and mood in irritable bowel syndrome patients.
Rezazadegan M; Soheilipour M; Amani R · Scientific reports · 2026
Randomized trial84 participantsflagGeneral Health forscienceZinc
- Effect of zinc sulfate supplementation on premenstrual syndrome and health-related quality of life: Clinical randomized controlled trial.
Siahbazi S; Behboudi-Gandevani S; Moghaddam-Banaem L; Montazeri A · The journal of obstetrics and gynaecology research · 2018
Randomized trial142 participantsflagGeneral Health forscienceZinc
- The Role of Sesbania grandiflora-Derived Biotin and Bambusa arundinacea-Derived Silica Extracts in Promoting Hair, Skin, and Nail Health: A Randomized, Double-Blind, Placebo-Controlled Clinical Study.
Patel MN; Maheshvari J; Patel N · Cureus · 2025
Randomized trial105 participantsflagHair Health flagNail Health flagSkin Health forscienceBiotin
- Low serum biotinidase activity in children with valproic acid monotherapy.
Schulpis KH; Karikas GA; Tjamouranis J; Regoutas S; Tsakiris S · Epilepsia · 2001
Clinical trial125 participantsflagHair Health flagSkin Health forscienceBiotin
- Vitamins A, B, C, and D: A Short Review for the Dermatologist.
Coerdt KM; Goggins CA; Khachemoune A · Alternative therapies in health and medicine · 2021
Narrative reviewflagHair Health forscienceBiotin
- The Infatuation With Biotin Supplementation: Is There Truth Behind Its Rising Popularity? A Comparative Analysis of Clinical Efficacy versus Social Popularity.
Soleymani T; Lo Sicco K; Shapiro J · Journal of drugs in dermatology : JDD · 2018
Narrative reviewflagHair Health forscienceBiotin
- Menkes disease and response to copper histidine: An Indian case series.
Yoganathan S; Sudhakar SV; Arunachal G; Thomas M; Subramanian A; George R; Danda S · Annals of Indian Academy of Neurology · 2022
Case series4 participantsflagHair Health forscienceCopper
- Trace element levels in alopecia areata.
Bhat YJ; Manzoor S; Khan AR; Qayoom S · Indian journal of dermatology, venereology and leprology · 2009
Case-control study100 participantsflagHair Health forscienceCopper
- UV damage to hair and the effect of antioxidants and metal chelators.
Millington KR; Marsh JM · International journal of cosmetic science · 2021
In vitro / ex vivo studyflagHair Health forscienceCopper
- Preserving fibre health: reducing oxidative stress throughout the life of the hair fibre.
Marsh JM; Davis MG; Lucas RL; Reilman R; Styczynski PB; Li C; Mamak M; McComb DW; Williams RE; Godfrey S; Navqi KR; Chechik V · International journal of cosmetic science · 2016
In vitro / ex vivo studyflagHair Health forscienceCopper
- Hair Loss After Metabolic and Bariatric Surgery: a Systematic Review and Meta-analysis.
Zhang W; Fan M; Wang C; Mahawar K; Parmar C; Chen W; Yang W; Global Bariatric Research Collaborative · Obesity surgery · 2021
Meta-analysis2,538 participants18 studies pooledflagHair Health forscienceFolate
- Quantitative Analysis of Selected Circulating Hematological Biomarkers, Essential Minerals, Vitamins, and Thyroid Hormones in Females Affected by Hair Loss.
Al-Fawaeir S; Al-Odat I · Diseases (Basel, Switzerland) · 2025
Case-control study200 participantsflagHair Health forscienceFolate flagHair Health forscienceVitamin B12
- Twelve weeks of protracted venous infusion of fluorouracil (5-FU) is as effective as 6 months of bolus 5-FU and folinic acid as adjuvant treatment in colorectal cancer.
Saini A; Norman AR; Cunningham D; Chau I; Hill M; Tait D; Hickish T; Iveson T; Lofts F; Jodrell D; Ross PJ; Oates J · British journal of cancer · 2003
Randomized trialflagHair Health forscienceFolate
- Role of oxaliplatin combined with 5-fluorouracil and folinic acid in the first- and second-line treatment of advanced colorectal cancer.
Jonker D; Rumble RB; Maroun J; Gastrointestinal Cancer Disease Site Groupof Cancer Care Ontario’s Program in Evidence-Based Care · Current oncology (Toronto, Ont.) · 2012
Randomized trialflagHair Health forscienceFolate
- Phase I-II study of vinorelbine in combination with 5-fluorouracil and folinic acid as first-line chemotherapy in metastatic breast cancer: a regimen with a low subjective toxic burden.
Nolè F; de Braud F; Aapro M; Minchella I; De Pas TM; Zampino MG; Monti S; Andreoni G; Goldhirsch A · Annals of oncology : official journal of the European Society for Medical Oncology · 1997
Randomized trialflagHair Health forscienceFolate
- Beyond Efficacy: 0.6% Selenium Disulfide Shampoo Matches 2% Ketoconazole for Seborrheic Dermatitis with Superior Cosmesis.
Farris PK; Barbosa V; Houshman EB; Kovylkina N · Journal of drugs in dermatology : JDD · 2026
Randomized trial87 participantsflagHair Health forscienceSelenium
- Selenium Disulfide-based shampoo applied for 4 weeks significantly improves dandruff and seborrheic dermatitis.
Turcu G; Artenie C; Nowicka D; Arenbergerová M; Lazaridou E; Khobzei K; Ataseven A; Part M; Leclerc-Mercier S · European journal of dermatology : EJD · 2023
Observational study1,407 participantsflagHair Health forscienceSelenium
- A Comparative Randomized Clinical Study Assessing the Efficacy of a 1% Selenium Disulfide-Based Shampoo versus 2% Ketoconazole Shampoo in Subjects with Moderate to Severe Scalp Seborrheic Dermatitis.
Barbosa V; Melo DF; Vañó-Galván S; Lutchmanen-Kolanthan V; Sant'Anna B; Leclerc-Mercier S; Reygagne P · Skin appendage disorders · 2025
Randomized trial64 participantsflagHair Health forscienceSelenium
- Changes of serum trace elements level in patients with alopecia areata: A meta-analysis.
Jin W; Zheng H; Shan B; Wu Y · The Journal of dermatology · 2018
Meta-analysis764 participantsflagHair Health forscienceSelenium
- Scientific opinion on the tolerable upper intake level for selenium.
EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA); Turck D; Bohn T; Castenmiller J; de Henauw S; Hirsch-Ernst KI; Knutsen HK; Maciuk A; Mangelsdorf I; McArdle HJ; Peláez C; Pentieva K; Siani A; Thies F; Tsabouri S; Vinceti M; Aggett P; Crous Bou M; Cubadda F; Ciccolallo L; de Sesmaisons Lecarré A; Fabiani L; Titz A; Naska A · EFSA journal. European Food Safety Authority · 2023
Systematic reviewflagHair Health forscienceSelenium
- Factors Associated with Premature Hair Graying in a Young Indian Population.
Chakrabarty S; Krishnappa PG; Gowda DG; Hiremath J · International journal of trichology · 2016
Case-control study74 participantsflagHair Health forscienceVitamin B12
- Risk Factors for Pediatric Alopecia Areata: Clinical and Biochemical Findings from a Case - Control Study.
İritaş SY · Dermatology practical & conceptual · 2026
Case-control study600 participantsflagHair Health forscienceVitamin B12
- Hair Loss After Laparoscopic Sleeve Gastrectomy.
Katsogridaki G; Tzovaras G; Sioka E; Perivoliotis K; Zachari E; Magouliotis D; Tasiopoulou V; Chatedaki C; Zacharoulis D · Obesity surgery · 2019
Cohort study50 participantsflagHair Health forscienceVitamin B12
- Demographic Characteristics and Association of Serum Vitamin B12, Ferritin and Thyroid Function with Premature Canities in Indian Patients from an Urban Skin Clinic of North India: A Retrospective Analysis of 71 Cases.
Sonthalia S; Priya A; Tobin DJ · Indian journal of dermatology · 2022
Cross-sectional study71 participantsflagHair Health forscienceVitamin B12
- Management of hair loss associated with endocrine therapy in patients with breast cancer: an overview.
Karatas F; Sahin S; Sever AR; Altundag K · SpringerPlus · 2016
Narrative reviewflagHair Health forscienceVitamin C
- Elucidating causal relationships of diet-derived circulating antioxidants and the risk of non-scarring alopecia: A Mendelian randomization study.
Ba Y; Shen L; Peng X; Zhang Y; Wang J · Medicine · 2024
Methods validation study201,019 participantsflagHair Health forscienceVitamin C
- Alterations of plasma antioxidants and mitochondrial DNA mutation in hair follicles of smokers.
Liu CS; Chen HW; Lii CK; Tsai CS; Kuo CL; Wei YH · Environmental and molecular mutagenesis · 2002
Observational studyflagHair Health forscienceVitamin C
- Removal of synthetic hair dye using formamidine sulfinic acid and other sulfinate precursors.
Hawkes JA; Lewis DM; Mama J; Murray J · International journal of cosmetic science · 2026
Methods validation studyflagHair Health forscienceVitamin C
- A Zinc Sulphate-Resistant Acrodermatitis Enteropathica Patient with a Novel Mutation in SLC39A4 Gene.
Kilic M; Taskesen M; Coskun T; Gürakan F; Tokatli A; Sivri HS; Dursun A; Schmitt S; Küry S · JIMD reports · 2013
Case reportflagHair Health forscienceVitamin C
- The effects of minoxidil, 1% pyrithione zinc and a combination of both on hair density: a randomized controlled trial.
Berger RS; Fu JL; Smiles KA; Turner CB; Schnell BM; Werchowski KM; Lammers KM · The British journal of dermatology · 2003
Randomized trial200 participantsflagHair Health forscienceZinc
- Incubatory environment of the scalp impacts pre-emergent hair to affect post-emergent hair cuticle integrity.
Schwartz JR; Henry JP; Kerr KM; Flagler MJ; Page SH; Redman-Furey N · Journal of cosmetic dermatology · 2018
Randomized trialflagHair Health forscienceZinc
- A comparison of hair quality and cosmetic acceptance following the use of two anti-dandruff shampoos.
Draelos ZD; Kenneally DC; Hodges LT; Billhimer W; Copas M; Margraf C · The journal of investigative dermatology. Symposium proceedings · 2006
Randomized trial40 participantsflagHair Health forscienceZinc
- BMI and levels of zinc, copper in hair, serum and urine of Turkish male patients with androgenetic alopecia.
Ozturk P; Kurutas E; Ataseven A; Dokur N; Gumusalan Y; Gorur A; Tamer L; Inaloz S · Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) · 2015
Case-control study216 participantsflagHair Health forscienceZinc
- Analysis of serum zinc and copper concentrations in hair loss.
Kil MS; Kim CW; Kim SS · Annals of dermatology · 2013
Case-control study342 participantsflagHair Health forscienceZinc
- Folic Acid Therapy Reduces the First Stroke Risk Associated With Hypercholesterolemia Among Hypertensive Patients.
Qin X; Li J; Spence JD; Zhang Y; Li Y; Wang X; Wang B; Sun N; Chen F; Guo J; Yin D; Sun L; Tang G; He M; Fu J; Cai Y; Shi X; Ye P; Chen H; Zhao S; Chen M; Gao C; Kong X; Hou FF; Huang Y; Huo Y · Stroke · 2017
Randomized trial20,702 participantsflagHeart Health forscienceFolate
- Periconception Red Blood Cell Folate and Offspring Congenital Heart Disease : Nested Case-Control and Mendelian Randomization Studies.
Chen H; Zhang Y; Wang D; Chen X; Li M; Huang X; Jiang Y; Dou Y; Wang Y; Ma X; Sheng W; Jia B; Yan W; Huang G; SPCC (Shanghai Preconception Cohort) Group · Annals of internal medicine · 2022
Case-control study985 participantsflagHeart Health forscienceFolate
- Intake of vitamin B6, folate, and vitamin B12 and risk of coronary heart disease: a systematic review and dose-response meta-analysis of prospective cohort studies.
Jayedi A; Zargar MS · Critical reviews in food science and nutrition · 2020
Meta-analysis369,746 participants11 studies pooledflagHeart Health forscienceFolate
- Folate Biomarkers, Folate Intake, and Risk of Death From All Causes, Cardiovascular Disease, and Cancer: A Systematic Review and Dose-Response Meta-Analysis of Prospective Cohort Studies.
Fallah M; Karim Dehnavi M; Lotfi K; Aminianfar A; Azadbakht L; Esmaillzadeh A · Nutrition reviews · 2025
Meta-analysis423,304 participants25 studies pooledflagHeart Health forscienceFolate
- The association between folic acid supplementation and congenital heart defects: Systematic review and meta-analysis.
Wondemagegn AT; Afework M · SAGE open medicine · 2022
Meta-analysis37 studies pooledflagHeart Health forscienceFolate
- Effects of magnesium supplementation on improving hyperglycemia, hypercholesterolemia, and hypertension in type 2 diabetes: A pooled analysis of 24 randomized controlled trials.
Xu L; Li X; Wang X; Xu M · Frontiers in nutrition · 2023
Meta-analysis1,325 participants24 studies pooledflagHeart Health forscienceMagnesium
- The effect of lowering blood pressure by magnesium supplementation in diabetic hypertensive adults with low serum magnesium levels: a randomized, double-blind, placebo-controlled clinical trial.
Guerrero-Romero F; Rodríguez-Morán M · Journal of human hypertension · 2009
Randomized trial82 participantsflagHeart Health forscienceMagnesium
- Positive effects of magnesium supplementation in metabolic syndrome.
Kisters S; Kisters K; Werner T; Vormann J; Tokmak F; Westhoff T; Gröber U; Predel HG; Reuter H · International journal of clinical pharmacology and therapeutics · 2024
Randomized trial54 participantsflagHeart Health forscienceMagnesium
- Vitamin B12 deficiency is associated with cardiovascular autonomic neuropathy in patients with type 2 diabetes.
Hansen CS; Jensen JS; Ridderstråle M; Vistisen D; Jørgensen ME; Fleischer J · Journal of diabetes and its complications · 2018
Cross-sectional study469 participantsflagHeart Health forscienceVitamin B12
- Vitamin B12 and folate status in early pregnancy and cardiometabolic risk factors in the offspring at age 5-6 years: findings from the ABCD multi-ethnic birth cohort.
Krikke GG; Grooten IJ; Vrijkotte TG; van Eijsden M; Roseboom TJ; Painter RC · BJOG : an international journal of obstetrics and gynaecology · 2016
Cohort study1,950 participantsflagHeart Health forscienceVitamin B12
- Orthostatic tolerance in older patients with vitamin B12 deficiency before and after vitamin B12 replacement.
Moore A; Ryan J; Watts M; Pillay I; Clinch D; Lyons D · Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2004
Non-randomized trial16 participantsflagHeart Health forscienceVitamin B12
- The impact of folic acid/VB12 deficiency on essential hypertension in children and adolescents: from a nested case-control and a cohort study.
Liang X; Huang D; Bi Y; He Y; Mao T; Liu Q; Hu G; Tong J; Chen L; Wang Y; An X; Jiang X; Tahir MF · Journal of human hypertension · 2024
Observational study596 participantsflagHeart Health forscienceVitamin B12
- Effects of selenium supplementation on selenoprotein gene expression and response to influenza vaccine challenge: a randomised controlled trial.
Goldson AJ; Fairweather-Tait SJ; Armah CN; Bao Y; Broadley MR; Dainty JR; Furniss C; Hart DJ; Teucher B; Hurst R · PloS one · 2011
Randomized trial119 participantsflagImmunity forscienceSelenium
- Effect of selenium on immune response against hepatitis B vaccine with accelerated method in insulin-dependent diabetes mellitus patients.
Janbakhsh A; Mansouri F; Vaziri S; Sayad B; Afsharian M; Rahimi M; Shahebrahimi K; Salari F · Caspian journal of internal medicine · 2013
Randomized trial62 participantsflagImmunity forscienceSelenium
- Chemoprevention trial of human hepatitis with selenium supplementation in China.
Yu SY; Li WG; Zhu YJ; Yu WP; Hou C · Biological trace element research · 1990
Non-randomized trial20,847 participantsflagImmunity forscienceSelenium
- Selenium nanoparticles as adjunctive therapy in sepsis: A pilot randomized clinical trial.
Gu WJ; Huang W; Zhao FZ; Yuan XK; Jin K; Chen JL; Zhang CY; Huang Y; He L; Zhuang H; Yin HY; Chen T · Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy · 2026
Randomized trial70 participantsflagImmunity forscienceSelenium
- Selenium supplementation in patients with autoimmune thyroiditis decreases thyroid peroxidase antibodies concentrations.
Gärtner R; Gasnier BC; Dietrich JW; Krebs B; Angstwurm MW · The Journal of clinical endocrinology and metabolism · 2002
Randomized trial70 participantsflagImmunity forscienceSelenium
- Depressed immune response to tetanus in children with vitamin A deficiency.
Semba RD; Muhilal; Scott AL; Natadisastra G; Wirasasmita S; Mele L; Ridwan E; West KP; Sommer A · The Journal of nutrition · 1992
Randomized trial236 participantsflagImmunity forscienceVitamin A
- Impact of a single megadose of vitamin A at delivery on breastmilk of mothers and morbidity of their infants.
Roy SK; Islam A; Molla A; Akramuzzaman SM; Jahan F; Fuchs G · European journal of clinical nutrition · 1997
Randomized trial50 participantsflagImmunity forscienceVitamin A
- Vitamin A supplementation reduces measles morbidity in young African children: a randomized, placebo-controlled, double-blind trial.
Coutsoudis A; Broughton M; Coovadia HM · The American journal of clinical nutrition · 1991
Randomized trial60 participantsflagImmunity forscienceVitamin A
- Vitamin A supplementation enhances specific IgG antibody levels and total lymphocyte numbers while improving morbidity in measles.
Coutsoudis A; Kiepiela P; Coovadia HM; Broughton M · The Pediatric infectious disease journal · 1992
Randomized trial60 participantsflagImmunity forscienceVitamin A
- Vitamin A supplementation reduces the monocyte chemoattractant protein-1 intestinal immune response of Mexican children.
Long KZ; Santos JI; Estrada Garcia T; Haas M; Firestone M; Bhagwat J; Dupont HL; Hertzmark E; Rosado JL; Nanthakumar NN · The Journal of nutrition · 2006
Randomized trial127 participantsflagImmunity forscienceVitamin A
- Vitamin C and contribution to the normal function of the immune system: evaluation of a health claim pursuant to Article 14 of Regulation (EC) No 1924/2006.
EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) · EFSA journal. European Food Safety Authority · 2026
Guideline / consensusflagImmunity forscienceVitamin C
- Therapeutic effects of high-dose vitamin C supplementation in patients with COVID-19: a meta-analysis.
Sun L; Zhao JH; Fan WY; Feng B; Liu WW; Chen RQ; Ban C; Dang AG; Wang M; Luo KT; Zhou GY; Yu FF; Ba Y · Nutrition reviews · 2024
Meta-analysis2,334 participants14 studies pooledflagImmunity forscienceVitamin C
- Effect of micronutrient supplements on influenza and other respiratory tract infections among adults: a systematic review and meta-analysis.
Abioye AI; Bromage S; Fawzi W · BMJ global health · 2021
Meta-analysisflagImmunity forscienceVitamin C
- New evidence for antioxidant properties of vitamin C.
Vojdani A; Bazargan M; Vojdani E; Wright J · Cancer detection and prevention · 2001
Randomized trial20 participantsflagImmunity forscienceVitamin C
- Enhanced Vitamin C Delivery: A Systematic Literature Review Assessing the Efficacy and Safety of Alternative Supplement Forms in Healthy Adults.
Calder PC; Kreider RB; McKay DL · Nutrients · 2025
Systematic review13 studies pooledflagImmunity forscienceVitamin C
- Vitamin D supplementation to prevent acute respiratory infections: individual participant data meta-analysis.
Martineau AR; Jolliffe DA; Greenberg L; Aloia JF; Bergman P; Dubnov-Raz G; Esposito S; Ganmaa D; Ginde AA; Goodall EC; Grant CC; Janssens W; Jensen ME; Kerley CP; Laaksi I; Manaseki-Holland S; Mauger D; Murdoch DR; Neale R; Rees JR; Simpson S; Stelmach I; Trilok Kumar G; Urashima M; Camargo CA; Griffiths CJ; Hooper RL · Health technology assessment (Winchester, England) · 2020
Meta-analysis11,321 participants25 studies pooledflagImmunity forscienceVitamin D
- Association Between Vitamin D and Influenza: Meta-Analysis and Systematic Review of Randomized Controlled Trials.
Zhu Z; Zhu X; Gu L; Zhan Y; Chen L; Li X · Frontiers in nutrition · 2022
Meta-analysis4,859 participants10 studies pooledflagImmunity forscienceVitamin D
- Vitamin D3 and deconvoluting a rash.
Ernst MK; Evans ST; Techner JM; Rothbaum RM; Christensen LF; Onay UV; Biyashev D; Demczuk MM; Nguyen CV; Honda KS; McCormick TS; Tsoi LC; Gudjonsson JE; Cooper KD; Lu KQ · JCI insight · 2023
Randomized trial28 participantsflagImmunity forscienceVitamin D
- Effect of vitamin D3 supplementation on cellular immunity and inflammatory markers in COVID-19 patients admitted to the ICU.
Bychinin MV; Klypa TV; Mandel IA; Yusubalieva GM; Baklaushev VP; Kolyshkina NA; Troitsky AV · Scientific reports · 2022
Randomized trial110 participantsflagImmunity forscienceVitamin D
- Current opinion on the role of vitamin D supplementation in respiratory infections and asthma/COPD exacerbations: A need to establish publication guidelines for overcoming the unpublished data.
Anitua E; Tierno R; Alkhraisat MH · Clinical nutrition (Edinburgh, Scotland) · 2022
Meta-analysis50,554 participants65 studies pooledflagImmunity forscienceVitamin D
- Nutrient supplementation for prevention of viral respiratory tract infections in healthy subjects: A systematic review and meta-analysis.
Vlieg-Boerstra B; de Jong N; Meyer R; Agostoni C; De Cosmi V; Grimshaw K; Milani GP; Muraro A; Oude Elberink H; Pali-Schöll I; Roduit C; Sasaki M; Skypala I; Sokolowska M; van Splunter M; Untersmayr E; Venter C; O'Mahony L; Nwaru BI · Allergy · 2022
Meta-analysis199,055 participants115 studies pooledflagImmunity forscienceZinc
- Zinc supplementation reduces the incidence of acute lower respiratory infections in infants and preschool children: a double-blind, controlled trial.
Sazawal S; Black RE; Jalla S; Mazumdar S; Sinha A; Bhan MK · Pediatrics · 1998
Randomized trial609 participantsflagImmunity forscienceZinc
- A randomized controlled trial of zinc supplementation in the treatment of acute respiratory tract infection in Thai children.
Rerksuppaphol S; Rerksuppaphol L · Pediatric reports · 2020
Randomized trial64 participantsflagImmunity forscienceZinc
- The effect of zinc and vitamin A supplementation on immune response in an older population.
Fortes C; Forastiere F; Agabiti N; Fano V; Pacifici R; Virgili F; Piras G; Guidi L; Bartoloni C; Tricerri A; Zuccaro P; Ebrahim S; Perucci CA · Journal of the American Geriatrics Society · 1998
Randomized trial136 participantsflagImmunity forscienceZinc
- The role of specific nutrients in preventing immune system and blood cell disorders: an umbrella review.
Vecchietti A; Strano P; Minutolo G; Grieco V; Cappuccio G; Granvillano G; Confalonieri L; Briganti GL; Raso E; Chimienti M; Pellegrini M; Mercogliano M; Spatari G; Lugli C; Urbano T; Lorenzon A · Journal of preventive medicine and hygiene · 2026
Systematic review13 studies pooledflagImmunity forscienceZinc
- Elevated intakes of supplemental chromium improve glucose and insulin variables in individuals with type 2 diabetes.
Anderson RA; Cheng N; Bryden NA; Polansky MM; Cheng N; Chi J; Feng J · Diabetes · 1997
Randomized trial180 participantsflagMetabolism Boost forscienceChromium
- Chromium Supplementation and the Effects on Metabolic Status in Women with Polycystic Ovary Syndrome: A Randomized, Double-Blind, Placebo-Controlled Trial.
Jamilian M; Asemi Z · Annals of nutrition & metabolism · 2016
Randomized trial64 participantsflagMetabolism Boost forscienceChromium
- A Comprehensive insight into the effect of chromium supplementation on oxidative stress indices in diabetes mellitus: A systematic review.
Kooshki F; Tutunchi H; Vajdi M; Karimi A; Niazkar HR; Shoorei H; Pourghassem Gargari B · Clinical and experimental pharmacology & physiology · 2024
Systematic review33 studies pooledflagMetabolism Boost forscienceChromium
- Comparison of nutritional supplements in improving glycolipid metabolism and endocrine function in polycystic ovary syndrome: a systematic review and network meta-analysis.
Hu X; Wang W; Su X; Peng H; Tan Z; Li Y; Huang Y · PeerJ · 2023
Meta-analysis2,362 participants41 studies pooledflagMetabolism Boost forscienceChromium flagMetabolism Boost forscienceSelenium
- [Chromium supplementation in patients with type 2 diabetes and high risk of type 2 diabetes: a meta-analysis of randomized controlled trials].
San Mauro-Martin I; Ruiz-León AM; Camina-Martín MA; Garicano-Vilar E; Collado-Yurrita L; Mateo-Silleras Bd; Redondo Del Río Mde P · Nutricion hospitalaria · 2017
Meta-analysis13 studies pooledflagMetabolism Boost forscienceChromium
- Iodine Supplementation Decreases Hypercholesterolemia in Iodine-Deficient, Overweight Women: A Randomized Controlled Trial.
Herter-Aeberli I; Cherkaoui M; El Ansari N; Rohner R; Stinca S; Chabaa L; von Eckardstein A; Aboussad A; Zimmermann MB · The Journal of nutrition · 2015
Randomized trial163 participantsflagMetabolism Boost forscienceIodine
- Effect of oral iodized oil on thyroid size and thyroid hormone metabolism in children with concurrent selenium and iodine deficiency.
Zimmermann MB; Adou P; Torresani T; Zeder C; Hurrell RF · European journal of clinical nutrition · 2000
Single-arm trial51 participantsflagMetabolism Boost forscienceIodine
- Serum Iodine Concentration as a Biomarker for Individual Iodine Nutrition and Thyroid Function in Pregnant Women: A Cross-Sectional Study in Hubei Province.
Xu M; Dai X; Wang Z; Guo C; Zhang B; Guo H · Public health nutrition · 2026
Cross-sectional study1,197 participantsflagMetabolism Boost forscienceIodine
- Iron status influences the efficacy of iodine prophylaxis in goitrous children in Côte d'Ivoire.
Zimmermann MB · International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition · 2002
OtherflagMetabolism Boost forscienceIodine
- Persistence of goiter despite oral iodine supplementation in goitrous children with iron deficiency anemia in Côte d'Ivoire.
Zimmermann M; Adou P; Torresani T; Zeder C; Hurrell R · The American journal of clinical nutrition · 2000
Non-randomized trial109 participantsflagMetabolism Boost forscienceIodine
- Association of magnesium consumption with type 2 diabetes and glucose metabolism: A systematic review and pooled study with trial sequential analysis.
Zhao B; Deng H; Li B; Chen L; Zou F; Hu L; Wei Y; Zhang W · Diabetes/metabolism research and reviews · 2021
Meta-analysis1,168 participants26 studies pooledflagMetabolism Boost forscienceMagnesium
- Magnesium supplementation for glycemic status in women with gestational diabetes: a systematic review and meta-analysis.
Tan X; Huang Y · Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology · 2022
Meta-analysis4 studies pooledflagMetabolism Boost forscienceMagnesium
- Impact of oral magnesium supplementation on glycemic and cardiometabolic outcomes in prediabetic adults: a systematic review and meta-analysis.
Basit A; Kumar S; Ahmed H; Babar R; Saeed SS; Siddiqui TA; Khan S; Saeed A; Khan M; Hanif H; Fasih A; Shabbir S; Kumar H; Kumar L; Raja A; Kumar S; Chander S · Journal of diabetes and metabolic disorders · 2026
Meta-analysis384 participants5 studies pooledflagMetabolism Boost forscienceMagnesium
- Oral magnesium supplementation improves insulin sensitivity and metabolic control in type 2 diabetic subjects: a randomized double-blind controlled trial.
Rodríguez-Morán M; Guerrero-Romero F · Diabetes care · 2003
Randomized trial63 participantsflagMetabolism Boost forscienceMagnesium
- Magnesium Supplementation and the Effects on Wound Healing and Metabolic Status in Patients with Diabetic Foot Ulcer: a Randomized, Double-Blind, Placebo-Controlled Trial.
Razzaghi R; Pidar F; Momen-Heravi M; Bahmani F; Akbari H; Asemi Z · Biological trace element research · 2018
Randomized trial70 participantsflagMetabolism Boost forscienceMagnesium
- Metabolic response to selenium supplementation in women with polycystic ovary syndrome: a randomized, double-blind, placebo-controlled trial.
Jamilian M; Razavi M; Fakhrie Kashan Z; Ghandi Y; Bagherian T; Asemi Z · Clinical endocrinology · 2016
Randomized trial70 participantsflagMetabolism Boost forscienceSelenium
- The Effects of Selenium Supplementation on Gene Expression Related to Insulin and Lipid Metabolism, and Pregnancy Outcomes in Patients with Gestational Diabetes Mellitus: a Randomized, Double-Blind, Placebo-Controlled Trial.
Karamali M; Dastyar F; Badakhsh MH; Aghadavood E; Amirani E; Asemi Z · Biological trace element research · 2021
Randomized trial36 participantsflagMetabolism Boost forscienceSelenium
- Glycemic and lipid responses to selenium-enriched vs. zeaxanthin-enriched eggs in patients with type 2 diabetes: a 12-week randomized controlled trial.
Niu X; Zhang Y; Liu Y; Zhu Y; Fang B; Hu C; Xu X; Wang R; Sang Y; Zhang Q; Guo J · Frontiers in nutrition · 2026
Randomized trial58 participantsflagMetabolism Boost forscienceSelenium
- The efficacy and safety of nutrient supplements in the treatment of mental disorders: a meta-review of meta-analyses of randomized controlled trials.
Firth J; Teasdale SB; Allott K; Siskind D; Marx W; Cotter J; Veronese N; Schuch F; Smith L; Solmi M; Carvalho AF; Vancampfort D; Berk M; Stubbs B; Sarris J · World psychiatry : official journal of the World Psychiatric Association (WPA) · 2025
Systematic review10,951 participants33 studies pooledflagMood Support forscienceFolate
- Continuous supplementation of folic acid in pregnancy and the risk of perinatal depression-A meta-analysis.
Jin X; Cheng Z; Yu X; Tao Q; Huang R; Wang S · Journal of affective disorders · 2022
Meta-analysis26,275 participants15 studies pooledflagMood Support forscienceFolate
- Efficacy of B-vitamins and vitamin D therapy in improving depressive and anxiety disorders: a systematic review of randomized controlled trials.
Borges-Vieira JG; Cardoso CKS · Nutritional neuroscience · 2023
Systematic review2,256 participants20 studies pooledflagMood Support forscienceFolate flagMood Support forscienceVitamin B12
- Folate supplementation as a beneficial add-on treatment in relieving depressive symptoms: A meta-analysis of meta-analyses.
Gao S; Khalid A; Amini-Salehi E; Radkhah N; Jamilian P; Badpeyma M; Zarezadeh M · Food science & nutrition · 2024
Meta-analysis11 studies pooledflagMood Support forscienceFolate
- Oral 5'-methyltetrahydrofolic acid in senile organic mental disorders with depression: results of a double-blind multicenter study.
Passeri M; Cucinotta D; Abate G; Senin U; Ventura A; Stramba Badiale M; Diana R; La Greca P; Le Grazie C · Aging (Milan, Italy) · 1993
Randomized trial96 participantsflagMood Support forscienceFolate
- Protective role of antioxidant supplementation for depression and anxiety: A meta-analysis of randomized clinical trials.
Wang H; Jin M; Xie M; Yang Y; Xue F; Li W; Zhang M; Li Z; Li X; Jia N; Liu Y; Cui X; Hu G; Dong L; Wang G; Yu Q · Journal of affective disorders · 2023
Meta-analysis4,049 participants52 studies pooledflagMood Support forscienceMagnesium
- Role of magnesium supplementation in the treatment of depression: A randomized clinical trial.
Tarleton EK; Littenberg B; MacLean CD; Kennedy AG; Daley C · PloS one · 2017
Randomized trial126 participantsflagMood Support flagStress Relief forscienceMagnesium
- Magnesium supplementation as an adjunct to fluoxetine therapy for depression.
Walyddaini AS; Lisal ST; Ilhamuddin; Zainuddin AA; Tanra AJ; Widianingsih Y; Syamsuddin S · East Asian archives of psychiatry : official journal of the Hong Kong College of Psychiatrists = Dong Ya jing shen ke xue zhi : Xianggang jing shen ke yi xue yuan qi kan · 2026
Randomized trial40 participantsflagMood Support forscienceMagnesium
- The effects of magnesium supplementation on serum level of brain derived neurotrophic factor (BDNF) and depression status in patients with depression.
Afsharfar M; Shahraki M; Shakiba M; Asbaghi O; Dashipour A · Clinical nutrition ESPEN · 2021
Randomized trial46 participantsflagMood Support forscienceMagnesium
- Dietary magnesium intake and risk of depression.
Sun C; Wang R; Li Z; Zhang D · Journal of affective disorders · 2019
Cross-sectional study17,730 participantsflagMood Support forscienceMagnesium
- Subjective well-being in older adults: folate and vitamin B12 independently predict positive affect.
Edney LC; Burns NR; Danthiir V · The British journal of nutrition · 2016
Cohort study391 participantsflagMood Support forscienceVitamin B12
- Association between of vitamin B12 status during pregnancy and probable postpartum depression: the ECLIPSES study.
Cruz-Rodríguez J; Canals-Sans J; Hernández-Martínez C; Arija V · Journal of reproductive and infant psychology · 2025
Cohort study336 participantsflagMood Support forscienceVitamin B12
- The biological relationship among depression, vitamins B9, B12, and D, and genetic variants: a systematic review.
Soriano-Gonzalez R; Ramirez-Olea H; Gonzalez-Soltero R; Chavez-Santoscoy RA · Frontiers in nutrition · 2025
Systematic review24 studies pooledflagMood Support forscienceVitamin B12
- Associations of dietary B vitamins intakes with depression in adults.
Wu Y; Li S; Wang W; Zhang D · International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition · 2023
Observational study17,732 participantsflagMood Support forscienceVitamin B12 flagMood Support forscienceVitamin B6
- High Dose Vitamin B6 Reduces Depression Symptoms.
Field DT; Cracknell R; Biagi N · Depression and anxiety · 2026
Randomized trial267 participantsflagMood Support forscienceVitamin B6
- Can Vitamin B6 Help to Prevent Postpartum Depression? A Randomized Controlled Trial.
Khodadad M; Bahadoran P; Kheirabadi GR; Sabzghabaee AM · International journal of preventive medicine · 2022
Randomized trial81 participantsflagMood Support forscienceVitamin B6
- Associations of Dietary Intake of Vitamin B6 and Plasma Pyridoxal 5'-Phosphate Level With Depression in US Adults: Findings From NHANES 2005-2010.
Lu J; Mao H; Tan Y; Luo G · Brain and behavior · 2024
Cross-sectional study24,683 participantsflagMood Support forscienceVitamin B6
- Impact of vitamin B6 status on psychological distress in a longitudinal study of HIV-1 infection.
Shor-Posner G; Feaster D; Blaney NT; Rocca H; Mantero-Atienza E; Szapocznik J; Eisdorfer C; Goodkin K; Baum MK · International journal of psychiatry in medicine · 1995
Cohort study88 participantsflagMood Support forscienceVitamin B6
- Zinc in depression: From development to treatment: A comparative/ dose response meta-analysis of observational studies and randomized controlled trials.
Yosaee S; Clark CCT; Keshtkaran Z; Ashourpour M; Keshani P; Soltani S · General hospital psychiatry · 2022
Meta-analysisflagMood Support forscienceZinc
- Dietary zinc and iron intake and risk of depression: A meta-analysis.
Li Z; Li B; Song X; Zhang D · Psychiatry research · 2017
Meta-analysis9 studies pooledflagMood Support forscienceZinc
- Zinc sulphate: A reasonable choice for depression management in patients with multiple sclerosis: A randomized, double-blind, placebo-controlled clinical trial.
Salari S; Khomand P; Arasteh M; Yousefzamani B; Hassanzadeh K · Pharmacological reports : PR · 2016
Randomized trial43 participantsflagMood Support forscienceZinc
- Comparative efficacy and tolerability of nutraceuticals for depressive disorder: A systematic review and network meta-analysis.
Cheng YC; Huang WL; Chen WY; Huang YC; Kuo PH; Tu YK · Psychological medicine · 2025
Meta-analysis17,437 participants192 studies pooledflagMood Support forscienceZinc
- Clinician guidelines for the treatment of psychiatric disorders with nutraceuticals and phytoceuticals: The World Federation of Societies of Biological Psychiatry (WFSBP) and Canadian Network for Mood and Anxiety Treatments (CANMAT) Taskforce.
Sarris J; Ravindran A; Yatham LN; Marx W; Rucklidge JJ; McIntyre RS; Akhondzadeh S; Benedetti F; Caneo C; Cramer H; Cribb L; de Manincor M; Dean O; Deslandes AC; Freeman MP; Gangadhar B; Harvey BH; Kasper S; Lake J; Lopresti A; Lu L; Metri NJ; Mischoulon D; Ng CH; Nishi D; Rahimi R; Seedat S; Sinclair J; Su KP; Zhang ZJ; Berk M · The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry · 2022
Guideline / consensusflagMood Support forscienceZinc
- Biotin for the treatment of nail disease: what is the evidence?
Lipner SR; Scher RK · The Journal of dermatological treatment · 2018
Narrative reviewflagNail Health forscienceBiotin
- Treatment of brittle fingernails and onychoschizia with biotin: scanning electron microscopy.
Colombo VE; Gerber F; Bronhofer M; Floersheim GL · Journal of the American Academy of Dermatology · 1991
Other32 participantsflagNail Health forscienceBiotin
- Treatment of brittle nail with a hydroxypropyl chitosan-based lacquer, alone or in combination with oral biotin: A randomized, assessor-blinded trial.
Chiavetta A; Mazzurco S; Secolo MP; Tomarchio G; Milani M · Dermatologic therapy · 2020
Randomized trial50 participantsflagNail Health forscienceBiotin
- Vitamins and minerals: their role in nail health and disease.
Scheinfeld N; Dahdah MJ; Scher R · Journal of drugs in dermatology : JDD · 2007
Narrative reviewflagNail Health forscienceBiotin flagNail Health forscienceZinc
- Acute selenium toxicity associated with a dietary supplement.
MacFarquhar JK; Broussard DL; Melstrom P; Hutchinson R; Wolkin A; Martin C; Burk RF; Dunn JR; Green AL; Hammond R; Schaffner W; Jones TF · Archives of internal medicine · 2010
Observational study201 participantsflagNail Health forscienceSelenium
- Vitamin C Deficiency in Inflammatory Bowel Disease: The Forgotten Micronutrient.
Dunleavy KA; Ungaro RC; Manning L; Gold S; Novak J; Colombel JF · Crohn's & colitis 360 · 2023
Other20 participantsflagNail Health forscienceVitamin C
- Evaluation of biophysical skin parameters and hair changes in patients with acne vulgaris treated with isotretinoin, and the effect of biotin use on these parameters.
Aksac SE; Bilgili SG; Yavuz GO; Yavuz IH; Aksac M; Karadag AS · International journal of dermatology · 2021
Non-randomized trial60 participantsflagSkin Health forscienceBiotin
- Generalized seborrhoeic dermatitis. Clinical and therapeutic data of 25 patients.
Messaritakis J; Kattamis C; Karabula C; Matsaniotis N · Archives of disease in childhood · 1976
Non-randomized trial25 participantsflagSkin Health forscienceBiotin
- Holocarboxylase synthetase deficiency: novel clinical and molecular findings.
Tammachote R; Janklat S; Tongkobpetch S; Suphapeetiporn K; Shotelersuk V · Clinical genetics · 2010
Case series4 participantsflagSkin Health forscienceBiotin
- Noninferiority of Copper Dressings Than Negative Pressure Wound Therapy in Healing Diabetic Wounds: A Randomized Clinical Trial.
Melamed E; Dabbah J; Israel T; Kan I; Pinzur MS; Roth T; Borkow G · Advances in wound care · 2026
Randomized trialflagSkin Health forscienceCopper
- Improvement of facial skin characteristics using copper oxide containing pillowcases: a double-blind, placebo-controlled, parallel, randomized study.
Borkow G; Gabbay J; Lyakhovitsky A; Huszar M · International journal of cosmetic science · 2010
Randomized trial57 participantsflagSkin Health forscienceCopper
- Radially Electrospun Fibrous Membrane Incorporated with Copper Peroxide Nanodots Capable of Self-Catalyzed Chemodynamic Therapy for Angiogenesis and Healing Acceleration of Diabetic Wounds.
Huang Y; Qi L; Liu Z; Jiang Y; Wang J; Liu L; Li Y; Zhang L; Feng G · ACS applied materials & interfaces · 2023
Animal experimentflagSkin Health forscienceCopper
- Engineering copper nanoparticle/polysaccharide-immobilized cotton gauze for accelerated healing of Staphylococcus aureus-infected dermal wounds.
Sahoo M; Banerjee T; Virkar S; Das S; Biswas S; Mitra D · Journal of materials chemistry. B · 2026
Animal experimentflagSkin Health forscienceCopper
- Stimulation of Healing of Non-Infected Stagnated Diabetic Wounds by Copper Oxide-Impregnated Wound Dressings.
Melamed E; Rovitsky A; Roth T; Assa L; Borkow G · Medicina (Kaunas, Lithuania) · 2021
Single-arm trialflagSkin Health forscienceCopper
- Effect of Evening Primrose Oil on Korean Patients With Mild Atopic Dermatitis: A Randomized, Double-Blinded, Placebo-Controlled Clinical Study.
Chung BY; Park SY; Jung MJ; Kim HO; Park CW · Annals of dermatology · 2022
Randomized trial50 participantsflagSkin Health forscienceGamma Linolenic Acid
- Meta-analysis of placebo-controlled studies of the efficacy of Epogam in the treatment of atopic eczema. Relationship between plasma essential fatty acid changes and clinical response.
Morse PF; Horrobin DF; Manku MS; Stewart JC; Allen R; Littlewood S; Wright S; Burton J; Gould DJ; Holt PJ · The British journal of dermatology · 1989
Meta-analysis9 studies pooledflagSkin Health forscienceGamma Linolenic Acid
- Reduced levels of prostaglandin precursors in the blood of atopic patients: defective delta-6-desaturase function as a biochemical basis for atopy.
Manku MS; Horrobin DF; Morse N; Kyte V; Jenkins K; Wright S; Burton JL · Prostaglandins, leukotrienes, and medicine · 1983
Non-randomized trial50 participantsflagSkin Health forscienceGamma Linolenic Acid
- Effect of borage oil consumption on fatty acid metabolism, transepidermal water loss and skin parameters in elderly people.
Brosche T; Platt D · Archives of gerontology and geriatrics · 2005
Non-randomized trial29 participantsflagSkin Health forscienceGamma Linolenic Acid
- Effects of oral supplementation with evening primrose oil for six weeks on plasma essential fatty acids and uremic skin symptoms in hemodialysis patients.
Yoshimoto-Furuie K; Yoshimoto K; Tanaka T; Saima S; Kikuchi Y; Shay J; Horrobin DF; Echizen H · Nephron · 1999
Randomized trial16 participantsflagSkin Health forscienceGamma Linolenic Acid
- Comparative clinical trial of bifonazole solution versus selenium sulphide shampoo in the treatment of pityriasis versicolor.
Chu AC · Dermatologica · 1985
Randomized trial38 participantsflagSkin Health forscienceSelenium
- Selenium supplementation and secondary prevention of nonmelanoma skin cancer in a randomized trial.
Duffield-Lillico AJ; Slate EH; Reid ME; Turnbull BW; Wilkins PA; Combs GF; Park HK; Gross EG; Graham GF; Stratton MS; Marshall JR; Clark LC; Nutritional Prevention of Cancer Study Group · Journal of the National Cancer Institute · 2003
Randomized trial1,312 participantsflagSkin Health forscienceSelenium
- Evidence-Based Nutritional Interventions in Wound Care.
Saeg F; Orazi R; Bowers GM; Janis JE · Plastic and reconstructive surgery · 2021
Systematic review2,339 participants36 studies pooledflagSkin Health forscienceSelenium flagSkin Health forscienceVitamin E flagSkin Health forscienceZinc
- A randomized, double-blind placebo-controlled trial evaluating the effects of vitamin E and selenium on arsenic-induced skin lesions in Bangladesh.
Verret WJ; Chen Y; Ahmed A; Islam T; Parvez F; Kibriya MG; Graziano JH; Ahsan H · Journal of occupational and environmental medicine · 2006
Randomized trial121 participantsflagSkin Health forscienceSelenium
- The Whitening, Moisturizing, Anti-aging Activities, and Skincare Evaluation of Selenium-Enriched Mung Bean Fermentation Broth.
Wei K; Guo C; Zhu J; Wei Y; Wu M; Huang X; Zhang M; Li J; Wang X; Wang Y; Wei X · Frontiers in nutrition · 2022
Clinical trial31 participantsflagSkin Health forscienceSelenium
- Efficacy and Tolerability of Topical 0.1% Stabilized Bioactive Retinol for Photoaging: A Vehicle-Controlled Integrated Analysis.
Farris P; Berson D; Bhatia N; Goldberg D; Lain E; Mariwalla K; Zeichner J; Miller D; McGuire T; Kizoulis M · Journal of drugs in dermatology : JDD · 2024
Meta-analysis471 participants6 studies pooledflagSkin Health forscienceVitamin A
- Tensile properties and contours of aging facial skin. A controlled double-blind comparative study of the effects of retinol, melibiose-lactose and their association.
Piérard-Franchimont C; Castelli D; Cromphaut IV; Bertin C; Ries G; Cauwenbergh G; Piérard GE · Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2016
Randomized trial120 participantsflagSkin Health forscienceVitamin A
- Antiaging action of retinol: from molecular to clinical.
Bellemère G; Stamatas GN; Bruère V; Bertin C; Issachar N; Oddos T · Skin pharmacology and physiology · 2009
Randomized trial48 participantsflagSkin Health forscienceVitamin A
- An Updated Review of Topical Tretinoin in Dermatology: From Acne and Photoaging to Skin Cancer.
Balado-Simó P; Morgado-Carrasco D; Gómez-Armayones S; López-Ferrer A; Barco D; Ferrándiz-Pulido C; Podlipnik S · Journal of clinical medicine · 2025
Narrative reviewflagSkin Health forscienceVitamin A
- Novel Cyclized Hexapeptide-9 Outperforms Retinol Against Skin Aging: A Randomized, Double-Blinded, Active- and Vehicle-Controlled Clinical Trial.
Chang H; Tao K; Yang Y; Wang Y; Ge M; Wang X; Tang S; Yu H · Journal of cosmetic dermatology · 2025
Randomized trialflagSkin Health forscienceVitamin A
- Evaluation of the anti-wrinkle effect of an ascorbic acid-loaded dissolving microneedle patch via a double-blind, placebo-controlled clinical study.
Lee C; Yang H; Kim S; Kim M; Kang H; Kim N; An S; Koh J; Jung H · International journal of cosmetic science · 2017
Randomized trial23 participantsflagSkin Health forscienceVitamin C
- Comparative Study on the Outcome of Periorbital Wrinkles Treated with Laser-Assisted Delivery of Vitamin C or Vitamin C Plus Growth Factors: A Randomized, Double-blind, Clinical Trial.
Machado BHB; Frame J; Zhang J; Najlah M · Aesthetic plastic surgery · 2021
Randomized trial149 participantsflagSkin Health forscienceVitamin C
- Randomized trial of topical ascorbic acid in DMSO versus imiquimod for the treatment of basal cell carcinoma.
Burke B; Bailie JE · Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2022
Randomized trial25 participantsflagSkin Health forscienceVitamin C
- Vitamin C improves healing of foot ulcers: a randomised, double-blind, placebo-controlled trial.
Gunton JE; Girgis CM; Lau T; Vicaretti M; Begg L; Flood V · The British journal of nutrition · 2022
Randomized trial16 participantsflagSkin Health forscienceVitamin C
- Dietary nutrient intakes and skin-aging appearance among middle-aged American women.
Cosgrove MC; Franco OH; Granger SP; Murray PG; Mayes AE · The American journal of clinical nutrition · 2007
Cross-sectional study4,025 participantsflagSkin Health forscienceVitamin C
- Randomized controlled trial using vitamins E and D supplementation in atopic dermatitis.
Javanbakht MH; Keshavarz SA; Djalali M; Siassi F; Eshraghian MR; Firooz A; Seirafi H; Ehsani AH; Chamari M; Mirshafiey A · The Journal of dermatological treatment · 2011
Randomized trial45 participantsflagSkin Health forscienceVitamin E
- Serum vitamin E levels and chronic inflammatory skin diseases: A systematic review and meta-analysis.
Liu X; Yang G; Luo M; Lan Q; Shi X; Deng H; Wang N; Xu X; Zhang C · PloS one · 2022
Meta-analysis20 studies pooledflagSkin Health forscienceVitamin E
- Effects of tocotrienol on aging skin: A systematic review.
Ghazali NI; Mohd Rais RZ; Makpol S; Chin KY; Yap WN; Goon JA · Frontiers in pharmacology · 2022
Systematic reviewflagSkin Health forscienceVitamin E
- Carotenoids and carotenoids plus vitamin E protect against ultraviolet light-induced erythema in humans.
Stahl W; Heinrich U; Jungmann H; Sies H; Tronnier H · The American journal of clinical nutrition · 2000
Randomized trialflagSkin Health forscienceVitamin E
- Sex-related differences in response to zinc pyrithione shampoo vs. non-anti-dandruff shampoo.
Collins LZ; Baines FL; Matheson JR; Turner GA; Diao Y; Li Y; Pi Y · International journal of cosmetic science · 2019
Meta-analysis2,088 participants20 studies pooledflagSkin Health forscienceZinc
- Maintenance of an Acidic Skin Surface with a Novel Zinc Lactobionate Emollient Preparation Improves Skin Barrier Function in Patients with Atopic Dermatitis.
Andrew PV; Pinnock A; Poyner A; Brown K; Chittock J; Kay LJ; Cork MJ; Danby SG · Dermatology and therapy · 2024
Cohort study23 participantsflagSkin Health forscienceZinc
- Spatial expression of metallothionein, matrix metalloproteinase-1 and Ki-67 in human epidermal wounds treated with zinc and determined by quantitative immunohistochemistry: A randomised double-blind trial.
Ågren MS; Chafranska L; Eriksen JO; Forman JL; Bjerrum MJ; Schjerling P; Larsen HF; Cottarelli E; Jorgensen LN; Gjerdrum LMR · European journal of cell biology · 2021
Randomized trial30 participantsflagSkin Health forscienceZinc
- A pilot trial using topical regular crystalline insulin vs. aqueous zinc solution for uncomplicated cutaneous wound healing: Impact on quality of life.
Attia EA; Belal DM; El Samahy MH; El Hamamsy MH · Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society · 2014
Randomized trial90 participantsflagSkin Health forscienceZinc
- Effects of magnesium and potassium supplementation on insomnia and sleep hormones in patients with diabetes mellitus.
Khalid S; Bashir S; Mehboob R; Anwar T; Ali M; Hashim M; Waseem H; Basharat S · Frontiers in endocrinology · 2024
Randomized trial320 participantsflagSleep Support forscienceMagnesium
- Association of magnesium intake with sleep duration and sleep quality: findings from the CARDIA study.
Zhang Y; Chen C; Lu L; Knutson KL; Carnethon MR; Fly AD; Luo J; Haas DM; Shikany JM; Kahe K · Sleep · 2022
Cohort study3,964 participantsflagSleep Support forscienceMagnesium
- Lidocaine vs. magnesium: effect on analgesia after a laparoscopic cholecystectomy.
Saadawy IM; Kaki AM; Abd El Latif AA; Abd-Elmaksoud AM; Tolba OM · Acta anaesthesiologica Scandinavica · 2010
Randomized trial120 participantsflagSleep Support forscienceMagnesium
- The effect of magnesium supplementation on primary insomnia in elderly: A double-blind placebo-controlled clinical trial.
Abbasi B; Kimiagar M; Sadeghniiat K; Shirazi MM; Hedayati M; Rashidkhani B · Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2013
Randomized trial46 participantsflagSleep Support forscienceMagnesium
- A randomized, double-blind, placebo-controlled, multicenter study assessing the efficacy of magnesium oxide monohydrate in the treatment of nocturnal leg cramps.
Barna O; Lohoida P; Holovchenko Y; Bazylevych A; Velychko V; Hovbakh I; Bula L; Shechter M · Nutrition journal · 2021
Randomized trial175 participantsflagSleep Support forscienceMagnesium
- Efficacy of vitamins B1 and B6 as an adjunctive therapy to lithium in bipolar-I disorder: A double-blind, randomized, placebo-controlled, clinical trial.
Zandifar A; Mousavi S; Schmidt NB; Badrfam R; Seif E; Qorbani M; Mehrabani Natanzi M · Journal of affective disorders · 2023
Randomized trial66 participantsflagSleep Support forscienceVitamin B6
- Therapeutic effects of magnesium and vitamin B6 in alleviating the symptoms of restless legs syndrome: a randomized controlled clinical trial.
Jadidi A; Rezaei Ashtiani A; Khanmohamadi Hezaveh A; Aghaepour SM · BMC complementary medicine and therapies · 2023
Randomized trial75 participantsflagSleep Support forscienceVitamin B6
- Effects of poly-gamma-glutamic acid and vitamin B6 supplements on sleep status: a randomized intervention study.
García-García C; Baik I · Nutrition research and practice · 2022
Randomized trial47 participantsflagSleep Support forscienceVitamin B6
- Effects of Vitamin B6 (Pyridoxine) and a B Complex Preparation on Dreaming and Sleep.
Adventure-Heart DJ; Madden NA; Delfabbro P · Perceptual and motor skills · 2018
Randomized trial100 participantsflagSleep Support forscienceVitamin B6
- The effect of pyridoxine administration on melatonin secretion in normal men.
Luboshitzky R; Ophir U; Nave R; Epstein R; Shen-Orr Z; Herer P · Neuro endocrinology letters · 2003
Randomized trial12 participantsflagSleep Support forscienceVitamin B6
- The effects of iron and/or zinc supplementation on maternal reports of sleep in infants from Nepal and Zanzibar.
Kordas K; Siegel EH; Olney DK; Katz J; Tielsch JM; Kariger PK; Khalfan SS; LeClerq SC; Khatry SK; Stoltzfus RJ · Journal of developmental and behavioral pediatrics : JDBP · 2009
Randomized trial1,444 participantsflagSleep Support forscienceZinc
- Effect of zinc supplementation on quality of life and sleep quality in young women with premenstrual syndrome: a randomized, double-blind, placebo-controlled trial.
Jafari F; Tarrahi MJ; Farhang A; Amani R · Archives of gynecology and obstetrics · 2020
Randomized trial60 participantsflagSleep Support forscienceZinc
- Skin-protective effects of a zinc oxide-functionalized textile and its relevance for atopic dermatitis.
Wiegand C; Hipler UC; Boldt S; Strehle J; Wollina U · Clinical, cosmetic and investigational dermatology · 2013
Non-randomized trialflagSleep Support forscienceZinc
- Associations of serum zinc, copper, and selenium with sleep disorders in the American adults: Data from NHANES 2011-2016.
Deng MG; Liu F; Liang Y; Chen Y; Nie JQ; Chai C; Wang K · Journal of affective disorders · 2023
Cross-sectional study3,660 participantsflagSleep Support forscienceZinc
- Magnesium and Zinc Are Associated with Sleep Quality in Saudi Adults: Evidence from a Cross-Sectional Study.
Al-Musharaf S; Aldhwayan MM; Mazi TA; Abujabir O; Alfawaz W; Aljuraiban GS · Nutrients · 2026
Cross-sectional study1,041 participantsflagSleep Support forscienceZinc
- An investigation into the stress-relieving and pharmacological actions of an ashwagandha (Withania somnifera) extract: A randomized, double-blind, placebo-controlled study.
Lopresti AL; Smith SJ; Malvi H; Kodgule R · Medicine · 2019
Randomized trial60 participantsflagStress Relief forscienceAshwagandha
- Shoden promotes Relief from stress and anxiety: A randomized, double-blind, placebo-controlled study on healthy subjects with high stress levels.
Mishra DN; Kumar M · Heliyon · 2024
Randomized trial60 participantsflagStress Relief forscienceAshwagandha
- Efficacy and Safety of Ashwagandha Root Extract on Cognitive Functions in Healthy, Stressed Adults: A Randomized, Double-Blind, Placebo-Controlled Study.
Gopukumar K; Thanawala S; Somepalli V; Rao TSS; Thamatam VB; Chauhan S · Evidence-based complementary and alternative medicine : eCAM · 2022
Randomized trial130 participantsflagStress Relief forscienceAshwagandha
- A prospective, randomized double-blind, placebo-controlled study of safety and efficacy of a high-concentration full-spectrum extract of ashwagandha root in reducing stress and anxiety in adults.
Chandrasekhar K; Kapoor J; Anishetty S · Indian journal of psychological medicine · 2013
Randomized trial64 participantsflagStress Relief forscienceAshwagandha
- Adaptogenic and Anxiolytic Effects of Ashwagandha Root Extract in Healthy Adults: A Double-blind, Randomized, Placebo-controlled Clinical Study.
Salve J; Pate S; Debnath K; Langade D · Cureus · 2020
Randomized trial60 participantsflagStress Relief forscienceAshwagandha
- Effects of Intravenous Esketamine or Magnesium Sulfate on Early Postoperative Negative Emotions and Pain in Patients Undergoing Endoscopic Sinus Surgery: A Randomized Controlled Trial.
Wang L; Zhou J; Liu Q; Qian K; Wang L; Xie C · Therapeutics and clinical risk management · 2026
Randomized trial137 participantsflagStress Relief forscienceMagnesium
- Effect of short-term magnesium supplementation on anxiety, depression and sleep quality in patients after open-heart surgery.
Saba S; Faizi F; Sepandi M; Nehrir B · Magnesium research · 2022
Non-randomized trial60 participantsflagStress Relief forscienceMagnesium
- Effects of dry needling compared to magnesium infiltration in trigger points for patients with myofascial pain syndrome: a randomized controlled study in Tunisia.
Dhouibi J; Moncer R; Kalbousi N; Gaddour M; Laayouni S; Ouanes W; Kacem B; Jemni S · Korean journal of family medicine · 2026
Randomized trial45 participantsflagStress Relief forscienceMagnesium
- Effect of magnesium and vitamin B6 supplementation on mental health and quality of life in stressed healthy adults: Post-hoc analysis of a randomised controlled trial.
Noah L; Dye L; Bois De Fer B; Mazur A; Pickering G; Pouteau E · Stress and health : journal of the International Society for the Investigation of Stress · 2021
Randomized trialflagStress Relief forscienceMagnesium
- The Effectiveness of Rhodiola rosea L. Preparations in Alleviating Various Aspects of Life-Stress Symptoms and Stress-Induced Conditions-Encouraging Clinical Evidence.
Ivanova Stojcheva E; Quintela JC · Molecules (Basel, Switzerland) · 2022
Narrative reviewflagStress Relief forscienceRhodiola
- Stress management and the role of Rhodiola rosea: a review.
Anghelescu IG; Edwards D; Seifritz E; Kasper S · International journal of psychiatry in clinical practice · 2019
Narrative reviewflagStress Relief forscienceRhodiola
- Plant-based medicines for anxiety disorders, part 2: a review of clinical studies with supporting preclinical evidence.
Sarris J; McIntyre E; Camfield DA · CNS drugs · 2013
Narrative reviewflagStress Relief forscienceRhodiola
- Effects of Withania somnifera (L.) Dunal (Ashwagandha) on cognitive and physical function in adults: a systematic review and meta-analysis.
Zhu X; Zeng Q; Lei Y; Xu D · Frontiers in pharmacology · 2026
Meta-analysis1,249 participants20 studies pooledflagTestosterone Support forscienceAshwagandha
- Effect of standardized root extract of ashwagandha (Withania somnifera) on well-being and sexual performance in adult males: A randomized controlled trial.
Chauhan S; Srivastava MK; Pathak AK · Health science reports · 2024
Randomized trial50 participantsflagTestosterone Support forscienceAshwagandha
- Examining the Effects of Herbs on Testosterone Concentrations in Men: A Systematic Review.
Smith SJ; Lopresti AL; Teo SYM; Fairchild TJ · Advances in nutrition (Bethesda, Md.) · 2021
Systematic review32 studies pooledflagTestosterone Support forscienceAshwagandha
- Do "testosterone boosters" really increase serum total testosterone? A systematic review.
Morgado A; Tsampoukas G; Sokolakis I; Schoentgen N; Urkmez A; Sarikaya S · International journal of impotence research · 2024
Systematic review3 studies pooledflagTestosterone Support forscienceAshwagandha
- Safety and Tolerability of Withania somnifera Root Extract in Healthy Male Participants: A Pilot Randomized, Double-Blind, Placebo-Controlled Clinical Trial.
Vaidya N; Agarwal R; Kshirsagar P; Ganu G; Nagore D; Mehta A; Vora A; Nair S · Food science & nutrition · 2025
Randomized trial40 participantsflagTestosterone Support forscienceAshwagandha
- Biochemical and physiologic consequences of boron deprivation in humans.
Nielsen FH · Environmental health perspectives · 1995
Single-arm trial12 participantsflagTestosterone Support forscienceBoron
- Plasma boron and the effects of boron supplementation in males.
Green NR; Ferrando AA · Environmental health perspectives · 1995
Randomized trial19 participantsflagTestosterone Support forscienceBoron
- Comparative effects of daily and weekly boron supplementation on plasma steroid hormones and proinflammatory cytokines
Mohammad Reza Naghii, Mahmoud Mofid, Ali Reza Asgari, Mehdi Hedayati, Maryam-Saddat Daneshpour · Journal of Trace Elements in Medicine and Biology · 2011
Non-randomized trial8 participantsflagTestosterone Support forscienceBoron
- Magnesium and anabolic hormones in older men.
Maggio M; Ceda GP; Lauretani F; Cattabiani C; Avantaggiato E; Morganti S; Ablondi F; Bandinelli S; Dominguez LJ; Barbagallo M; Paolisso G; Semba RD; Ferrucci L · International journal of andrology · 2012
Cohort study399 participantsflagTestosterone Support forscienceMagnesium
- Analysis of the relationship between the blood concentration of several metals, macro- and micronutrients and endocrine disorders associated with male aging.
Rotter I; Kosik-Bogacka DI; Dołęgowska B; Safranow K; Kuczyńska M; Laszczyńska M · Environmental geochemistry and health · 2017
Cross-sectional study313 participantsflagTestosterone Support forscienceMagnesium
- Effect of magnesium supplementation in improving hyperandrogenism, hirsutism, and sleep quality in women with polycystic ovary syndrome: A randomized, placebo-controlled clinical trial.
Gholizadeh-Moghaddam M; Ghasemi-Tehrani H; Askari G; Jaripur M; Clark CCT; Rouhani MH · Health science reports · 2024
Randomized trial64 participantsflagTestosterone Support forscienceMagnesium
- The effects of trace element supplementation on glycolipid metabolism in PCOS: a systematic review and meta-analysis.
Yang L; Gao Y; Zhao W; Qi Y; Duo X; Wang H · Frontiers in nutrition · 2025
Meta-analysis1,600 participants25 studies pooledflagTestosterone Support forscienceMagnesium
- Effects of magnesium supplementation on testosterone levels of athletes and sedentary subjects at rest and after exhaustion.
Cinar V; Polat Y; Baltaci AK; Mogulkoc R · Biological trace element research · 2011
Non-randomized trial20 participantsflagTestosterone Support forscienceMagnesium
- Efficacy of selenium and/or N-acetyl-cysteine for improving semen parameters in infertile men: a double-blind, placebo controlled, randomized study.
Safarinejad MR; Safarinejad S · The Journal of urology · 2009
Randomized trial468 participantsflagTestosterone Support forscienceSelenium
- The association between metal exposure and semen quality in Chinese males: The mediating effect of androgens.
Liu P; Yuan G; Zhou Q; Liu Y; He X; Zhang H; Guo Y; Wen Y; Huang S; Ke Y; Chen J · Environmental pollution (Barking, Essex : 1987) · 2020
Cross-sectional study1,136 participantsflagTestosterone Support forscienceSelenium
- In utero and peripubertal metals exposure in relation to reproductive hormones and sexual maturation and progression among girls in Mexico City.
Ashrap P; Sánchez BN; Téllez-Rojo MM; Basu N; Tamayo-Ortiz M; Peterson KE; Meeker JD; Watkins DJ · Environmental research · 2019
Observational study132 participantsflagTestosterone Support forscienceSelenium
- Relationship between serum levels of testosterone, zinc and selenium in infertile males attending fertility clinic in Nnewi, south east Nigeria.
Oluboyo AO; Adijeh RU; Onyenekwe CC; Oluboyo BO; Mbaeri TC; Odiegwu CN; Chukwuma GO; Onwuasoanya UF · African journal of medicine and medical sciences · 2013
Observational studyflagTestosterone Support forscienceSelenium
- EVALUATION OF MALE SEX HORMONES AND TRACE ELEMENTS IN MALE TYPE 2 DIABETIC PATIENTS ATTENDING NNAMDI AZIKIWE UNIVERSITY TEACHING HOSPITAL DIABETIC CLINICS.
Ubajaka CF; Meludu SC; Dioka CE; Onah CE; Osuji CU; Modebe IA; Ifeadike GC; Okwara JE; Amah UK; Nnebue CC · Nigerian journal of medicine : journal of the National Association of Resident Doctors of Nigeria · 2015
Cross-sectional studyflagTestosterone Support forscienceSelenium
- Efficacy of Tribulus Terrestris for the treatment of premenopausal women with hypoactive sexual desire disorder: a randomized double-blinded, placebo-controlled trial.
Vale FBC; Zanolla Dias de Souza K; Rezende CR; Geber S · Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology · 2018
Randomized trial40 participantsflagTestosterone Support forscienceTribulus
- The Effects of 6 Weeks of Tribulus terrestris L. Supplementation on Body Composition, Hormonal Response, Perceived Exertion, and CrossFit® Performance: A Randomized, Single-Blind, Placebo-Controlled Study.
Fernández-Lázaro D; Mielgo-Ayuso J; Del Valle Soto M; Adams DP; González-Bernal JJ; Seco-Calvo J · Nutrients · 2021
Randomized trial30 participantsflagTestosterone Support forscienceTribulus
- Tribulus terrestris versus placebo in the treatment of erectile dysfunction and lower urinary tract symptoms in patients with late-onset hypogonadism: A placebo-controlled study.
GamalEl Din SF; Abdel Salam MA; Mohamed MS; Ahmed AR; Motawaa AT; Saadeldin OA; Elnabarway RR · Urologia · 2019
Randomized trial70 participantsflagTestosterone Support forscienceTribulus
- Efficacy of Tribulus terrestris for the treatment of hypoactive sexual desire disorder in postmenopausal women: a randomized, double-blinded, placebo-controlled trial.
de Souza KZ; Vale FB; Geber S · Menopause (New York, N.Y.) · 2018
Randomized trial45 participantsflagTestosterone Support forscienceTribulus
- Effect of oral administration of Tribulus terrestris extract on semen quality and body fat index of infertile men.
Salgado RM; Marques-Silva MH; Gonçalves E; Mathias AC; Aguiar JG; Wolff P · Andrologia · 2018
Single-arm trial65 participantsflagTestosterone Support forscienceTribulus
- Effect of Two Different Doses of Vitamin D Supplementation on Metabolic Profiles of Insulin-Resistant Patients with Polycystic Ovary Syndrome.
Jamilian M; Foroozanfard F; Rahmani E; Talebi M; Bahmani F; Asemi Z · Nutrients · 2018
Randomized trial90 participantsflagTestosterone Support forscienceVitamin D
- Androgens and hirsutism score of overweight women with polycystic ovary syndrome improved after vitamin D treatment: A randomized placebo controlled clinical trial.
Al-Bayyari N; Al-Domi H; Zayed F; Hailat R; Eaton A · Clinical nutrition (Edinburgh, Scotland) · 2021
Randomized trial60 participantsflagTestosterone Support forscienceVitamin D
- Association between plasma 25-OH vitamin D and testosterone levels in men.
Nimptsch K; Platz EA; Willett WC; Giovannucci E · Clinical endocrinology · 2012
Case-control study1,362 participantsflagTestosterone Support forscienceVitamin D
- Causal Link Between Vitamin D and Total Testosterone in Men: A Mendelian Randomization Analysis.
Chen C; Zhai H; Cheng J; Weng P; Chen Y; Li Q; Wang C; Xia F; Wang N; Lu Y · The Journal of clinical endocrinology and metabolism · 2020
Other4,254 participantsflagTestosterone Support forscienceVitamin D
- Associations of vitamin D status and vitamin D-related polymorphisms with sex hormones in older men.
Rafiq R; van Schoor NM; Sohl E; Zillikens MC; Oosterwerff MM; Schaap L; Lips P; de Jongh RT · The Journal of steroid biochemistry and molecular biology · 2017
Cohort study643 participantsflagTestosterone Support forscienceVitamin D
- Environmental exposure to metals and male reproductive hormones: circulating testosterone is inversely associated with blood molybdenum.
Meeker JD; Rossano MG; Protas B; Padmanahban V; Diamond MP; Puscheck E; Daly D; Paneth N; Wirth JJ · Fertility and sterility · 2010
Cross-sectional study219 participantsflagTestosterone Support forscienceZinc
- Nonpharmacological Interventions for the Management of Testosterone and Sperm Parameters: A Scoping Review.
Santos HO; Cadegiani FA; Forbes SC · Clinical therapeutics · 2022
Scoping reviewflagTestosterone Support forscienceZinc
- Zinc is an Essential Element for Male Fertility: A Review of Zn Roles in Men's Health, Germination, Sperm Quality, and Fertilization.
Fallah A; Mohammad-Hasani A; Colagar AH · Journal of reproduction & infertility · 2020
Narrative reviewflagTestosterone Support forscienceZinc
- Clinical, endocrinological and biochemical effects of zinc deficiency.
Prasad AS · Clinics in endocrinology and metabolism · 1986
Narrative reviewflagTestosterone Support forscienceZinc
- Clinical, endocrinologic, and biochemical effects of zinc deficiency.
Prasad AS · Special topics in endocrinology and metabolism · 1986
Narrative reviewflagTestosterone Support forscienceZinc
- What did we learn in 35 years of research on nutrition and supplements for age-related macular degeneration: a systematic review.
Pameijer EM; Heus P; Damen JAA; Spijker R; Hooft L; Ringens PJ; Imhof SM; van Leeuwen R · Acta ophthalmologica · 2023
Systematic review27 studies pooledflagVision Support forscienceCopper
- Dietary Nutrient Intake and Progression to Late Age-Related Macular Degeneration in the Age-Related Eye Disease Studies 1 and 2.
Agrón E; Mares J; Clemons TE; Swaroop A; Chew EY; Keenan TDL; AREDS and AREDS2 Research Groups · Ophthalmology · 2021
Cohort study8,242 participantsflagVision Support forscienceCopper
- Association between late age-related macular degeneration and dietary intake of copper, iron, zinc and selenium: a 2005-2008 NHANES cross-sectional observational study.
Lu Y; Li C; Liu Y; Wu T; Lu P · BMC ophthalmology · 2025
Observational study4,996 participantsflagVision Support forscienceCopper
- Associations between dietary nutrient intake and the risk of multiple age-related ocular diseases: evidence from longitudinal analysis.
Yang Y; Zou H · The journal of nutrition, health & aging · 2026
Cohort study103,192 participantsflagVision Support forscienceCopper
- Dietary habits and dietary nutrient intake in patients with age-related macular degeneration: A case-control study.
Šalková Kráľová J; Kolář P; Kapounová Z; Veselý P; Derflerová Brázdová Z · Central European journal of public health · 2023
Case-control study151 participantsflagVision Support forscienceCopper
- Efficacy and safety of AZR-MD-001 selenium sulfide ophthalmic ointment in adults with meibomian gland dysfunction: A vehicle-controlled, randomized clinical trial.
Watson SL; Jones LW; Stapleton F; Hinds M; Ng A; Tan J; Alster Y; Bosworth C; Rafaeli O; DePuy V; CELESTIAL STUDY Group · The ocular surface · 2026
Randomized trial245 participantsflagVision Support forscienceSelenium
- Efficacy and safety of AZR-MD-001 selenium sulfide ophthalmic ointment in adults with meibomian gland dysfunction over six months of treatment: A Phase 2, vehicle-controlled, randomized extension trial.
Downie LE; Craig JP; Stapleton F; Tan J; Jones LW; Ng A; Hinds M; Bosworth C; Alster Y · The ocular surface · 2025
Randomized trial245 participantsflagVision Support forscienceSelenium
- AZR-MD-001 0.5% selenium sulfide ophthalmic ointment for the treatment of contact lens discomfort: A vehicle-controlled, randomized, clinical trial.
Stapleton F; Hinds M; Tan J; Jones L; Chalmers R; Bosworth C; Alster Y · The ocular surface · 2025
Randomized trial67 participantsflagVision Support forscienceSelenium
- The effect of a biweekly novel selenium sulfide-containing topical treatment in symptomatic contact lens wearers: An exploratory study.
Stapleton F; Jia T; DePuy V; Bosworth C; Gleeson M; Tan J · The ocular surface · 2025
Randomized trial14 participantsflagVision Support forscienceSelenium
- A randomized trial of vitamin A and vitamin E supplementation for retinitis pigmentosa.
Berson EL; Rosner B; Sandberg MA; Hayes KC; Nicholson BW; Weigel-DiFranco C; Willett W · Archives of ophthalmology (Chicago, Ill. : 1960) · 1993
Randomized trial601 participantsflagVision Support forscienceVitamin A
- Efficacy and safety of retinol palmitate ophthalmic solution in the treatment of dry eye: a Japanese Phase II clinical trial.
Toshida H; Funaki T; Ono K; Tabuchi N; Watanabe S; Seki T; Otake H; Kato T; Ebihara N; Murakami A · Drug design, development and therapy · 2018
Randomized trial66 participantsflagVision Support forscienceVitamin A
- Vitamin A supplementation for preventing morbidity and mortality in children from six months to five years of age.
Imdad A; Mayo-Wilson E; Haykal MR; Regan A; Sidhu J; Smith A; Bhutta ZA · The Cochrane database of systematic reviews · 2022
Meta-analysis1,223,856 participants47 studies pooledflagVision Support forscienceVitamin A
- Vitamin A supplementation improves retinal function in infants at risk of retinopathy of prematurity.
Mactier H; McCulloch DL; Hamilton R; Galloway P; Bradnam MS; Young D; Lavy T; Farrell L; Weaver LT · The Journal of pediatrics · 2012
Randomized trial89 participantsflagVision Support forscienceVitamin A
- Effect of short-term, high-dose retinol on dark adaptation in aging and early age-related maculopathy.
Owsley C; McGwin G; Jackson GR; Heimburger DC; Piyathilake CJ; Klein R; White MF; Kallies K · Investigative ophthalmology & visual science · 2006
Randomized trial104 participantsflagVision Support forscienceVitamin A
- Role of Oral Vitamin 'C' on Astigmatic Errors in Phacoemulsification.
Mohan S; Sah K; Khattri M; Ahmad L; Sachan SK · Current eye research · 2021
Randomized trial400 participantsflagVision Support forscienceVitamin C
- Ascorbic acid metabolites are involved in intraocular pressure control in the general population.
Hysi PG; Khawaja AP; Menni C; Tamraz B; Wareham N; Khaw KT; Foster PJ; Benet LZ; Spector TD; Hammond CJ · Redox biology · 2019
Observational studyflagVision Support forscienceVitamin C
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Weikel KA; Garber C; Baburins A; Taylor A · Nutrition reviews · 2014
Narrative reviewflagVision Support forscienceVitamin C
- Dietary n-3 Fatty Acid, α-Tocopherol, Zinc, vitamin D, vitamin C, and β-carotene are Associated with Age-Related Macular Degeneration in Japan.
Aoki A; Inoue M; Nguyen E; Obata R; Kadonosono K; Shinkai S; Hashimoto H; Sasaki S; Yanagi Y · Scientific reports · 2017
Case-control study530 participantsflagVision Support forscienceVitamin C flagVision Support forscienceVitamin E
- Adherence to a Mediterranean diet, lifestyle and age-related macular degeneration: the Coimbra Eye Study - report 3.
Raimundo M; Mira F; Cachulo MDL; Barreto P; Ribeiro L; Farinha C; Laíns I; Nunes S; Alves D; Figueira J; Merle BM; Delcourt C; Santos L; Silva R · Acta ophthalmologica · 2019
Case-control study883 participantsflagVision Support forscienceVitamin C
- Antioxidant vitamin and mineral supplements for preventing age-related macular degeneration.
Evans JR; Lawrenson JG · The Cochrane database of systematic reviews · 2018
Meta-analysis55,614 participants4 studies pooledflagVision Support forscienceVitamin E
- Dietary carotenoids, vitamins C and E, and risk of cataract in women: a prospective study.
Christen WG; Liu S; Glynn RJ; Gaziano JM; Buring JE · Archives of ophthalmology (Chicago, Ill. : 1960) · 2008
Cohort study35,551 participantsflagVision Support forscienceVitamin E
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Cohort study408 participantsflagVision Support forscienceVitamin E
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Cohort study4,765 participantsflagVision Support forscienceVitamin E
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Evans JR · The Cochrane database of systematic reviews · 2002
Systematic review170 participants7 studies pooledflagVision Support forscienceZinc
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Evans JR; Lawrenson JG · The Cochrane database of systematic reviews · 2023
Meta-analysis3,790 participants5 studies pooledflagVision Support forscienceZinc
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Randomized trial151 participantsflagVision Support forscienceZinc
- A randomized, placebo-controlled, clinical trial of high-dose supplementation with vitamins C and E, beta carotene, and zinc for age-related macular degeneration and vision loss: AREDS report no. 8.
Age-Related Eye Disease Study Research Group · Archives of ophthalmology (Chicago, Ill. : 1960) · 2001
Randomized trial3,640 participantsflagVision Support forscienceZinc
- Effect of vitamin A and zinc supplementation on the nutriture of children in Northeast Thailand.
Udomkesmalee E; Dhanamitta S; Sirisinha S; Charoenkiatkul S; Tuntipopipat S; Banjong O; Rojroongwasinkul N; Kramer TR; Smith JC · The American journal of clinical nutrition · 1992
Randomized trial133 participantsflagVision Support forscienceZinc