New MOOD
Onnit
New MOOD
4.3
★ ★ ★ ★ ★
(364 ratings)
Vitamin B6 20 mg
Niacin 30 mg
Tryptophan 400 mg
5-HTP 150 mg
Score 80.0
Onnit New MOOD is a blend targeting mood, stress, and sleep with key ingredients like 5-HTP, Tryptophan, B vitamins, and magnesium, offering a convenient multi-faceted approach despite its proprietary blend and higher price point.
Quantity: 60 Capsule(s)Servings size: 2 Capsule(s) (30 servings)
Selected goals:
Other goals:
Energy
Brain Health
Mood Support
General Health
Heart Health
leaderboard Score 80.0
Onnit New MOOD is a blend targeting mood, stress, and sleep with key ingredients like 5-HTP, Tryptophan, B vitamins, and magnesium, offering a convenient multi-faceted approach despite its proprietary blend and higher price point.
insights Analysis
New MOOD by Onnit is formulated as a comprehensive supplement primarily aimed at mood, stress, and sleep support. It features a blend of serotonin precursors (L-Tryptophan and 5-HTP), essential co-factors (Vitamin B6, Niacin) for serotonin synthesis, and Magnesium Bisglycinate Chelate, a highly absorbable form of magnesium known for its calming properties. The inclusion of Vitamin D3 further adds to general well-being and mood regulation. While the individual dosages of the known ingredients are generally effective for their intended purposes, the product's proprietary 'Onnit Tranquility Blend' lacks transparency regarding the specific quantities of its components, making a full assessment of its contribution impossible. The price per serving is on the higher end when compared to single-ingredient alternatives or some other multi-ingredient formulas in the market.
- Contains well-researched ingredients (5-HTP, L-Tryptophan, Magnesium, B6, Niacin, D3) known for mood, stress, and sleep support.
- Uses highly bioavailable forms of magnesium (Bisglycinate Chelate) and a no-flush form of niacin (Inositol Hexanicotinate).
- Offers a convenient, comprehensive solution for interconnected goals of mood, stress, and sleep.
- The 'Onnit Tranquility Blend' is proprietary, meaning the specific amounts of its constituent ingredients are not disclosed, hindering full efficacy assessment.
- The price per serving ($1.99) is relatively high compared to purchasing individual ingredients or other similar multi-ingredient formulas.
- The dosage of Magnesium (40mg) is lower than often recommended for significant stress or sleep support, potentially requiring additional supplementation.
- Individuals taking antidepressant medications (SSRIs, MAOIs) should consult a healthcare professional before taking New MOOD due to the risk of serotonin syndrome from 5-HTP and L-Tryptophan.
- Pregnant or nursing women, individuals with pre-existing medical conditions, or those on other medications should seek medical advice prior to use.
$59.89($1.99 per serving)
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bolt Effectiveness for goals
Niacin, or Vitamin B3, is primarily known for its role in supporting healthy cholesterol levels, specifically lowering LDL (bad) cholesterol and increasing HDL (good) cholesterol. It also plays a vital part in energy metabolism and DNA repair. Medical supervision is recommended for high-dose use for cholesterol management.
5-HTP is a precursor to serotonin, a neurotransmitter involved in mood, sleep, and appetite regulation. It is commonly taken as a supplement to support mood balance and healthy sleep patterns. Its direct conversion to serotonin bypasses an initial metabolic step.
Vitamin B6 is essential for numerous bodily functions, including protein metabolism, red blood cell formation, and nervous system health. It also supports immune function and cognitive development. It is a cofactor in many enzymatic reactions.
L-Tryptophan is an essential amino acid that serves as a precursor to serotonin, melatonin, and niacin. It is commonly supplemented to support sleep quality and mood regulation. As an essential amino acid, it must be obtained through diet or supplementation.
Yes, Vitamin B6 is a crucial cofactor for the enzyme that converts 5-HTP to serotonin. Adequate B6 levels are therefore important for the body's efficient conversion of Tryptophan to 5-HTP, and subsequently to serotonin. Some supplements combine them for this reason.
schedule Dosage, timing & forms
Daily dosages for niacin vary significantly based on the form and the intended use. For general nutritional support, doses are typically lower, while therapeutic doses for cholesterol management can be much higher and require medical supervision. Always consult product labels or a healthcare provider for appropriate dosing.
For general dietary supplementation, common daily dosages of Vitamin B6 typically range from 1.3 mg to 10 mg. Higher doses are sometimes used for specific conditions under medical guidance, but excessive intake can lead to adverse effects. Always follow recommended guidelines on product labels.
Niacin is commonly found as nicotinic acid, niacinamide (nicotinamide), and inositol hexanicotinate (flush-free niacin). Each form has distinct properties regarding its effects and potential side effects. The choice of form often depends on the desired outcome and individual tolerance.
A common starting dosage for 5-HTP is often 50 mg to 100 mg per day. Dosages can be adjusted upwards, typically not exceeding 300-400 mg daily, but this should be done cautiously and under guidance. Always begin with the lowest effective dose.
Common dosages for L-Tryptophan can range from 500 mg to 2000 mg per day, depending on the intended use. It is often recommended to start with a lower dose and gradually increase it as needed. Always consult product instructions or a healthcare professional for appropriate dosing.
health_and_safety Safety & interactions
Serotonin Syndrome is a potentially dangerous condition caused by too much serotonin in the brain, leading to symptoms like agitation, confusion, rapid heart rate, muscle rigidity, and fever. Combining 5-HTP with other serotonin-increasing drugs, such as SSRI antidepressants, MAOIs, or certain migraine medications, can significantly increase the risk. Medical supervision is crucial when considering such combinations.
Yes, L-Tryptophan can interact with antidepressants, particularly selective serotonin reuptake inhibitors (SSRIs), monoamine oxidase inhibitors (MAOIs), and tricyclic antidepressants (TCAs). This combination may increase the risk of serotonin syndrome, a potentially serious condition caused by excessive serotonin levels in the brain. Consultation with a healthcare provider is recommended.
Yes, Vitamin B6 is a critical cofactor in the metabolism of both L-Tryptophan and 5-HTP. It is necessary for the conversion of 5-HTP into serotonin in the brain. Adequate Vitamin B6 levels are important for these biochemical pathways to function efficiently.
Common side effects of 5-HTP include nausea, diarrhea, vomiting, and stomach pain, particularly at higher doses. It can also cause drowsiness or muscle problems. More serious concerns involve potential serotonin syndrome when combined with certain medications.
Long-term, high-dose Vitamin B6 supplementation can lead to peripheral neuropathy, a form of nerve damage. Symptoms may include numbness, tingling, and pain in the hands and feet. This risk generally increases with doses exceeding the tolerable upper intake level of 100 mg per day.
Ingredients
| Ingredient | Amount per serving |
|---|---|
| Vitamin D (Vitamin D3) | 25 mcg |
| Niacin (Inositol Hexanicotinate) | 30 mg |
| Vitamin B6 (Pyridoxine Hydrochloride) | 20 mg |
| Magnesium (Magnesium Bisglycinate Chelate) | 40 mg |
| Onnit Tranquility Blend | 450 mg |
| L-Tryptophan | 400 mg |
| 5-Hydroxytryptophan | 150 mg |
Categories
5-HTP 90.0
At 150mg, the 5-HTP content in New MOOD is robust and aligns with or exceeds the dosages often found in standalone 5-HTP supplements. This potent amount directly supports serotonin production, making it highly effective for the product's mood and sleep-related goals.
Vitamin B6 85.0
With 20mg of Pyridoxine Hydrochloride, New MOOD provides a strong and effective dose of Vitamin B6. This amount is sufficient to act as a crucial cofactor for the conversion of 5-HTP and L-Tryptophan into serotonin, enhancing the product's primary mood and sleep benefits.
Tryptophan 80.0
The product includes 400mg of L-Tryptophan, a significant dosage that works synergistically with 5-HTP to provide precursors for serotonin synthesis. While some standalone L-Tryptophan supplements offer 500mg, this amount is still very effective within the combined formula for its intended purpose.
Goals
Mood Support 90.0
The primary strength of New MOOD lies in its comprehensive approach to mood, combining L-Tryptophan and 5-HTP, which are direct precursors to serotonin, a key neurotransmitter for well-being. Additionally, Vitamin B6 acts as a crucial cofactor in this conversion, while magnesium and Vitamin D are also recognized for their roles in mood regulation.
Stress Relief 90.0
The combination of L-Tryptophan, 5-HTP, and particularly Magnesium Bisglycinate Chelate contributes significantly to stress reduction by promoting relaxation and supporting nervous system function. Vitamin B6 also plays a role in neurotransmitter production essential for stress response, making this product highly relevant for calming the mind.
Sleep Support 90.0
New MOOD is well-formulated for sleep, leveraging the serotonin pathway via L-Tryptophan and 5-HTP to aid melatonin production, the body's sleep hormone. The inclusion of magnesium, a known relaxant, further enhances its ability to promote restful sleep by soothing muscle tension and calming the nervous system.
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