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Vitamin K2 MK-7 (Menaquinone-7) 180 mcg

Carlson
4.8
★ ★ ★ ★ ★
(276 ratings)
Vitamin K 180 mcg
Product Image
Score80
A high-potency MK-7 softgel with clear active dosing. Two softgels and limited source detail weaken convenience and transparency.
How scoring works
Quantity:90 Softgel(s) • (45 servings)
Goals:
Heart Health
Bone Health
Cardiovascular Support
Anti-Aging
General Health

Score 80

A high-potency MK-7 softgel with clear active dosing. Two softgels and limited source detail weaken convenience and transparency.
How scoring works

Also available as

3 options
90.00mcg • 120 Softgel(s) servings K 90 mcg • 120 Softgel(s) • 120 servings $36.98 ($0.30 per serving) 90.00mcg • 60 Softgel(s) servings K 90 mcg • 60 Softgel(s) • 60 servings $19.13 ($0.31 per serving) 180 servings K 180 mcg • 180 Softgel(s) • 90 servings $54.74 ($0.60 per serving)
$29.24($0.64 per serving)
Pure Formulas
$ 29.24
iHerb
$ 29.24
Vitacost
$ 29.24
Report prices

Analysis

The daily serving supplies 180 mcg of menaquinone-7. That substantial amount suits focused K2 use without mixing in unrelated nutrients.

The label identifies the chemical form but not its raw source, branded ingredient, or carrier oil. Softgel delivery is appropriate for a fat-soluble vitamin, though the missing carrier detail prevents a fuller quality judgment.

Two softgels per serving add burden compared with many one-unit MK-7 products. It fits users intentionally seeking a higher K2 amount rather than basic maintenance.

Who is it for
  • Adults intentionally seeking higher-dose MK-7
  • People who prefer softgels
  • Users who manage vitamin D separately
Best for
  • Focused high-potency K2 use
  • Bone calcium-management support
  • Standalone MK-7 supplementation

Pros

  • Provides 180 mcg of MK-7
  • Clearly names menaquinone-7
  • Uses a softgel format
  • Avoids unrelated actives

Cons

  • Requires two softgels
  • Carrier oil is not identified
  • Raw MK-7 source is not stated
  • No vitamin D is included

Warnings

  • Vitamin K2 can oppose warfarin and related vitamin K antagonists, so intake should remain consistent with prescriber guidance.

Nutrient quality

94 Highest impact

Menaquinone-7 is a well-regarded, longer-acting vitamin K2 form. The higher vitamin K2 amount is meaningful for targeted supplementation.

Ingredient transparency

82 Highest impact

Every active ingredient has a specific amount. Inactive ingredients are not supplied.

Customer satisfaction

68 High impact

The supplied average indicates very strong aggregate satisfaction. No detailed experience reports are available to identify repeated complaints or confirm perceived benefits.

Value for money

71 High impact

The focused, well-formed ingredient provides reasonable value for the cost. Serving value appears moderate for a simple vitamin K supplement.

Report analysis

Goals

Heart Health
Heart Health
Impact
Highest effect
A- Goal FitA+ Strength of SupportC CoverageA+ Formula Quality
Vitamin K · 180 mcg

Vitamin K2 as MK-7 is strongly aligned with healthy calcium handling and arterial support. Human evidence is promising for vascular markers, though broad cardiovascular outcome evidence is still developing.

The 180 mcg amount is within an effective daily range and the softgel suits a fat-soluble vitamin. People taking warfarin or other vitamin K antagonist medicines should keep vitamin K intake consistent and follow their prescriber’s guidance.

Study evidence
Vitamin K Mixed 62 studies
Bone Health
Bone Health
Impact
Highest effect
B+ Goal FitA- Strength of SupportC- CoverageA Formula Quality
Vitamin K · 180 mcg

MK-7 directly supports activation of bone proteins that bind calcium into the matrix. Human evidence supports its role in vitamin K status and bone metabolism, although a stand-alone effect on fracture risk is less certain.

The 180 mcg amount is clearly disclosed and sits within a clinically used range. The softgel is practical, but its lipid carrier, branded source, and all-trans purity are not identified.

Study evidence
Vitamin K Supportive 78 studies
Cardiovascular Support
Cardiovascular Support
Impact
Highest effect
B- Goal FitA+ Strength of SupportD+ CoverageA+ Formula Quality
Vitamin K · 180 mcg

MK-7 supports activation of proteins that help direct calcium away from arteries and into bone. The 180 mcg amount is clearly disclosed and reaches a substantial daily range.

Evidence for effects on arterial stiffness or calcification is promising but less conclusive than evidence for established lipid or blood-pressure therapies. MK-7 can counteract warfarin, so people using vitamin K antagonist anticoagulants need consistent intake and clinician-guided monitoring.

Study evidence
Vitamin K Supportive 40 studies
Anti-Aging
Anti-Aging
Impact
Highest effect
B Goal FitA- Strength of SupportC- CoverageA Formula Quality
Vitamin K · 180 mcg

MK-7 supports proteins involved in keeping calcium in bones and out of soft tissues, which is relevant to vascular and skeletal aging. The serving provides a strong maintenance amount in a focused softgel.

The active form and quantity are clear, but the source, isomer purity, and lipid carrier are not identified. MK-7 can counteract warfarin, so stable intake and clinician-guided monitoring are important for users of that anticoagulant.

Study evidence
Vitamin K Supportive 27 studies
General Health
General Health
Impact
High effect
A- Goal FitC Strength of SupportB CoverageB- Formula Quality
Vitamin K · 180 mcg

The broad vitamin and mineral mix can help cover several everyday nutrient gaps, with useful amounts of vitamin C, vitamin D, folate, iodine, and selenium. Selenium is clearly disclosed and sits well below its upper intake limit, but sodium selenate is not the preferred retained form.

Some nutrients appear present in very small amounts, while a fruit and vegetable blend adds breadth without clear evidence of meaningful impact. The formula is better viewed as broad nutritional backup than as strong support for every pathway named on the label.

Ingredients

IngredientAmount per serving
Vitamin K2 (Menaquinone-7)
 180 mcg
Gluten Free Adults 18–50 Women
Report overview
Vitamin K (Menaquinone-7) · 180 mcg OverallScore86
B- Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyB+ Value

The 180 mcg MK-7 dose falls comfortably within the effective range for bone and cardiovascular support. The softgel format is practical, but the available label data do not identify a lipid carrier, studied source, or all-trans purity. The MK-7 can counteract warfarin, so people using this anticoagulant need consistent intake and clinician-guided monitoring.

View ingredientView products
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87 Performance

Vitamin K2 100 mcg

SR Sports Research
<p>The formula provides 100 mcg of Vitamin K2 (Menaquinone-7), which may be a better fit than the original’s 180 mcg of Vitamin K2 (Menaquinone-7) when its specific vitamin K form and companion nutrients are preferred. Vitamin K may interfere with warfarin-type anticoagulants, so people using them need clinician-directed intake.</p>
86 Performance

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<p>The formula provides 90 mcg of Vitamin K2 (Menaquinone-7), which may be a better fit than the original’s 180 mcg of Vitamin K2 (Menaquinone-7) when its specific vitamin K form and companion nutrients are preferred. Vitamin K may interfere with warfarin-type anticoagulants, so people using them need clinician-directed intake.</p>
87 Performance

Vitamin K2 as MK-7 100 mcg

Healthy Origins
<p>The formula provides 100 mcg of Vitamin K2 (Menaquinone-7), which may be a better fit than the original’s 180 mcg of Vitamin K2 (Menaquinone-7) when its specific vitamin K form and companion nutrients are preferred. Vitamin K may interfere with warfarin-type anticoagulants, so people using them need clinician-directed intake.</p>
88 Budget

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<p>At a lower recurring cost, the formula provides 100 mcg of Vitamin K (Menaquinone-7), making it a practical budget alternative to the original’s 180 mcg of Vitamin K2 (Menaquinone-7). Vitamin K may interfere with warfarin-type anticoagulants, so people using them need clinician-directed intake.</p>
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NOW
<p>At a lower recurring cost, the formula provides 100 mcg of Vitamin K2 (Menaquinone-7), making it a practical budget alternative to the original’s 180 mcg of Vitamin K2 (Menaquinone-7). Vitamin K may interfere with warfarin-type anticoagulants, so people using them need clinician-directed intake.</p>
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Vitamin K2 MenaQ7 100 mcg

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<p>At a lower recurring cost, the formula provides 100 mcg of Vitamin K2 (Natto), making it a practical budget alternative to the original’s 180 mcg of Vitamin K2 (Menaquinone-7). Vitamin K may interfere with warfarin-type anticoagulants, so people using them need clinician-directed intake.</p>
86 Value

Vitamins D3 2500 IU (62.5 mcg) & K2 120 mcg

NaturesPlus
<p>The formula combines 120 mcg of Vitamin K2 (Menaquinone-7) and 62.50 mcg of Vitamin D3 (Cholecalciferol) with favorable serving value, which may offer a better quality-to-cost balance than the original’s 180 mcg of Vitamin K2 (Menaquinone-7). Vitamin K may interfere with warfarin-type anticoagulants, so people using them need clinician-directed intake.</p>
87 Value

MK-7 Vitamin K-2 100 mcg

NOW
<p>The formula combines 100 mcg of Vitamin K-2 (Menaquinone-7) with favorable serving value, which may offer a better quality-to-cost balance than the original’s 180 mcg of Vitamin K2 (Menaquinone-7). Vitamin K may interfere with warfarin-type anticoagulants, so people using them need clinician-directed intake.</p>
86 Value

Vitamin K2 100 mcg + Vitamin D3 125 mcg

Nutricost
<p>The formula combines 100 mcg of Vitamin K (Menaquinone-7) and 125 mcg of Vitamin D (Cholecalciferol) with favorable serving value, which may offer a better quality-to-cost balance than the original’s 180 mcg of Vitamin K2 (Menaquinone-7). The high vitamin D amount warrants attention to total intake, and vitamin K may interfere with warfarin-type anticoagulants.</p>
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Three-year low-dose menaquinone-7 supplementation helps decrease bone loss in healthy postmenopausal women.
    Knapen MH; Drummen NE; Smit E; Vermeer C; Theuwissen E · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2014
    Randomized trial244 participantsBone Health forVitamin K
  2. Does vitamin K2 play a role in the prevention and treatment of osteoporosis for postmenopausal women: a meta-analysis of randomized controlled trials.
    Huang ZB; Wan SL; Lu YJ; Ning L; Liu C; Fan SW · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2015
    Meta-analysis6,759 participants19 studies pooledBone Health forVitamin K
  3. Investigating the interrelationship of vitamin K and vitamin D status on bone density: results from the VITamin D and OmegA-3 TriaL.
    Chou SH; Booth SL; Cook NR; Kim E; Kotler G; Fu X; Buring JE; Manson JE; LeBoff MS · JBMR plus · 2026
    Randomized trial771 participantsBone Health forVitamin K
  4. Comparison of concurrent treatment with vitamin K2 and risedronate compared with treatment with risedronate alone in patients with osteoporosis: Japanese Osteoporosis Intervention Trial-03.
    Tanaka S; Miyazaki T; Uemura Y; Miyakawa N; Gorai I; Nakamura T; Fukunaga M; Ohashi Y; Ohta H; Mori S; Hagino H; Hosoi T; Sugimoto T; Itoi E; Orimo H; Shiraki M · Journal of bone and mineral metabolism · 2018
    Randomized trial1,874 participantsBone Health forVitamin K
  5. Efficacy and safety of vitamin K2 for postmenopausal women with osteoporosis at a long-term follow-up: meta-analysis and systematic review.
    Zhou M; Han S; Zhang W; Wu D · Journal of bone and mineral metabolism · 2022
    Meta-analysis6,853 participants9 studies pooledBone Health forVitamin K
  6. Menaquinone-7 supplementation improves arterial stiffness in healthy postmenopausal women. A double-blind randomised clinical trial.
    Knapen MH; Braam LA; Drummen NE; Bekers O; Hoeks AP; Vermeer C · Thrombosis and haemostasis · 2016
    Randomized trial244 participantsCardiovascular Support Heart Health forVitamin K
  7. Effects of One-Year Menaquinone-7 Supplementation on Vascular Stiffness and Blood Pressure in Post-Menopausal Women.
    de Vries F; Bittner R; Maresz K; Machuron F; Gåserød O; Jeanne JF; Schurgers LJ · Nutrients · 2025
    Randomized trial165 participantsCardiovascular Support forVitamin K
  8. Vitamin K Intake and Atherosclerotic Cardiovascular Disease in the Danish Diet Cancer and Health Study.
    Bellinge JW; Dalgaard F; Murray K; Connolly E; Blekkenhorst LC; Bondonno CP; Lewis JR; Sim M; Croft KD; Gislason G; Torp-Pedersen C; Tjønneland A; Overvad K; Hodgson JM; Schultz C; Bondonno NP · Journal of the American Heart Association · 2021
    Cohort study53,372 participantsCardiovascular Support Heart Health forVitamin K
  9. Interventions to Attenuate Cardiovascular Calcification Progression: A Systematic Review of Randomized Clinical Trials.
    Murali S; Smith ER; Tiong MK; Tan SJ; Toussaint ND · Journal of the American Heart Association · 2024
    Systematic review9,901 participants49 studies pooledCardiovascular Support forVitamin K
  10. Intake of dietary phylloquinone and menaquinones and risk of stroke.
    Vissers LE; Dalmeijer GW; Boer JM; Monique Verschuren WM; van der Schouw YT; Beulens JW · Journal of the American Heart Association · 2014
    Cohort study35,476 participantsCardiovascular Support forVitamin K
  11. Circulating uncarboxylated matrix Gla protein, a marker of vitamin K status, as a risk factor of cardiovascular disease.
    van den Heuvel EG; van Schoor NM; Lips P; Magdeleyns EJ; Deeg DJ; Vermeer C; den Heijer M · Maturitas · 2014
    Cohort study577 participantsCardiovascular Support forVitamin K
  12. Vitamin K status, cardiovascular disease, and all-cause mortality: a participant-level meta-analysis of 3 US cohorts.
    Shea MK; Barger K; Booth SL; Matuszek G; Cushman M; Benjamin EJ; Kritchevsky SB; Weiner DE · The American journal of clinical nutrition · 2020
    Meta-analysis3,891 participants3 studies pooledAnti-Aging forVitamin K
  13. Topical Menaquinone‑7 (Vitamin K2, MK-7) as a Mitochondrial Bioenergetic Activator for Skin Anti-Aging: Mechanistic Evidence in Skin Cells and a Randomized Split-Face/Neck Study.
    Huang H; Wei R; Xu C; Liu C; Zhao S; Li Y; Wang M · ACS omega · 2026
    Randomized trial30 participantsAnti-Aging forVitamin K
  14. Vitamin K status and cognitive function in healthy older adults.
    Presse N; Belleville S; Gaudreau P; Greenwood CE; Kergoat MJ; Morais JA; Payette H; Shatenstein B; Ferland G · Neurobiology of aging · 2014
    Cross-sectional study320 participantsAnti-Aging forVitamin K
  15. High dephospho-uncarboxylated matrix Gla protein concentrations, a plasma biomarker of vitamin K, in relation to frailty: the Longitudinal Aging Study Amsterdam.
    Machado-Fragua MD; Hoogendijk EO; Struijk EA; Rodriguez-Artalejo F; Lopez-Garcia E; Beulens JW; van Ballegooijen AJ · European journal of nutrition · 2021
    Cohort study644 participantsAnti-Aging forVitamin K
  16. Vitamin K Concentration and Cognitive Status in Elderly Patients on Anticoagulant Therapy: A Pilot Study.
    Alisi L; Cafolla C; Gentili A; Tartaglione S; Curini R; Cafolla A · Journal of aging research · 2022
    Cross-sectional study85 participantsAnti-Aging forVitamin K
  17. Vitamin K and the prevention of fractures: systematic review and meta-analysis of randomized controlled trials.
    Cockayne S; Adamson J; Lanham-New S; Shearer MJ; Gilbody S; Torgerson DJ · Archives of internal medicine · 2006
    Meta-analysis13 studies pooledBone Health forVitamin K
  18. Effect of combined administration of vitamin D3 and vitamin K2 on bone mineral density of the lumbar spine in postmenopausal women with osteoporosis.
    Iwamoto J; Takeda T; Ichimura S · Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association · 2001
    Randomized trial92 participantsBone Health forVitamin K
  19. Low-dose vitamin K2 (MK-4) supplementation for 12 months improves bone metabolism and prevents forearm bone loss in postmenopausal Japanese women.
    Koitaya N; Sekiguchi M; Tousen Y; Nishide Y; Morita A; Yamauchi J; Gando Y; Miyachi M; Aoki M; Komatsu M; Watanabe F; Morishita K; Ishimi Y · Journal of bone and mineral metabolism · 2015
    Randomized trial48 participantsBone Health forVitamin K
  20. Dietary Vitamin K1 Intake and Incident Aortic Valve Stenosis.
    Schultz CJ; Dalgaard F; Bellinge JW; Murray K; Sim M; Connolly E; Blekkenhorst LC; Bondonno CP; Lewis JR; Gislason GH; Tjønneland A; Overvad K; Hodgson JM; Bondonno NP · Arteriosclerosis, thrombosis, and vascular biology · 2024
    Cohort study55,545 participantsCardiovascular Support Heart Health forVitamin K
  21. Association between vitamin K1 intake and mortality in the Danish Diet, Cancer, and Health cohort.
    Palmer CR; Bellinge JW; Dalgaard F; Sim M; Murray K; Connolly E; Blekkenhorst LC; Bondonno CP; Croft KD; Gislason G; Tjønneland A; Overvad K; Schultz C; Lewis JR; Hodgson JM; Bondonno NP · European journal of epidemiology · 2021
    Cohort study56,048 participantsCardiovascular Support Heart Health forVitamin K
  22. The effect of vitamin K1 on arterial calcification activity in subjects with diabetes mellitus: a post hoc analysis of a double-blind, randomized, placebo-controlled trial.
    Bellinge JW; Francis RJ; Lee SC; Bondonno NP; Sim M; Lewis JR; Watts GF; Schultz CJ · The American journal of clinical nutrition · 2022
    Randomized trial149 participantsHeart Health forVitamin K