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Vitamin K2 MK-7 (Menaquinone-7) 180 mcg

Carlson
4.8
★ ★ ★ ★ ★
(274 ratings)
Vitamin K 180 mcg
Product Image
Score81
A focused higher-dose MK-7 product with clear active dosing. Missing source and carrier details plus two softgels per serving reduce its appeal.
How scoring works
Quantity:180 Softgel(s) • (90 servings)
Goals:
Heart Health
General Health
Bone Health
Anti-Aging
Cardiovascular Support

Score 81

A focused higher-dose MK-7 product with clear active dosing. Missing source and carrier details plus two softgels per serving reduce its appeal.
How scoring works

Also available as

3 options
90.00mcg • 120 Softgel(s) servings K 90 mcg • 120 Softgel(s) • 120 servings $36.98 ($0.30 per serving) 90.00mcg • 60 Softgel(s) servings K 90 mcg • 60 Softgel(s) • 60 servings $19.13 ($0.31 per serving) 90 servings K 180 mcg • 90 Softgel(s) • 45 servings $29.24 ($0.64 per serving)
$54.74($0.60 per serving)
iHerb
$ 54.74
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Analysis

The daily serving supplies 180 mcg of menaquinone-7 without other active nutrients. The amount is substantial and aimed at users who deliberately want more than a basic maintenance serving.

Softgel delivery suits a fat-soluble vitamin, but the carrier oil and raw MK-7 source are not identified. Those gaps limit assessment of source quality and dietary compatibility.

Two softgels per serving create more burden than many standalone K2 products. It is a reasonable higher-dose option when vitamin D and mineral intake are already managed separately.

Who is it for
  • Adults intentionally seeking 180 mcg of MK-7
  • People managing vitamin D separately
  • Users who prefer softgels
Best for
  • Higher-potency standalone K2
  • Bone calcium-management support
  • Focused MK-7 supplementation

Pros

  • Provides 180 mcg of MK-7
  • Clearly names the K2 form
  • Uses a softgel delivery format
  • Contains no unrelated actives

Cons

  • Requires two softgels
  • Carrier oil is not disclosed
  • Raw MK-7 source is not identified
  • No vitamin D is included

Warnings

  • Vitamin K2 can oppose warfarin and related vitamin K antagonists, so intake should remain consistent with prescriber guidance.

Nutrient quality

94 Highest impact

Menaquinone-7 is a well-regarded, longer-acting vitamin K2 form. The higher vitamin K2 amount is meaningful for targeted supplementation.

Ingredient transparency

82 Highest impact

Every active ingredient has a specific amount. Inactive ingredients are not supplied.

Customer satisfaction

68 High impact

The supplied average indicates very strong aggregate satisfaction. No detailed experience reports are available to identify repeated complaints or confirm perceived benefits.

Value for money

76 High impact

The focused, well-formed ingredient provides reasonable value for the cost. Serving value appears moderate for a simple vitamin K supplement.

Report analysis

Goals

Heart Health
Heart Health
Impact
Highest effect
A- Goal FitA+ Strength of SupportC CoverageA+ Formula Quality
Vitamin K · 180 mcg

Vitamin K2 as MK-7 is strongly aligned with healthy calcium handling and arterial support. Human evidence is promising for vascular markers, though broad cardiovascular outcome evidence is still developing.

The 180 mcg amount is within an effective daily range and the softgel suits a fat-soluble vitamin. People taking warfarin or other vitamin K antagonist medicines should keep vitamin K intake consistent and follow their prescriber’s guidance.

Study evidence
Vitamin K Mixed 62 studies
General Health
General Health
Impact
Highest effect
B+ Goal FitA+ Strength of SupportC CoverageA Formula Quality
Vitamin K · 180 mcg

Vitamin K2 as MK-7 supports normal calcium handling in bone and vascular tissues. The clearly disclosed amount and long-lasting form provide strong depth for that specific pathway.

The single-nutrient formula is focused but does not cover broader nutritional or energy needs. MK-7 can reduce the effect of warfarin-type anticoagulants, so people using those medicines need consistent intake planned with their prescriber.

Study evidence
Vitamin K Supportive 34 studies
Bone Health
Bone Health
Impact
Highest effect
B+ Goal FitA- Strength of SupportC- CoverageA Formula Quality
Vitamin K · 180 mcg

MK-7 directly supports activation of bone proteins that bind calcium into the matrix. Human evidence supports its role in vitamin K status and bone metabolism, although a stand-alone effect on fracture risk is less certain.

The 180 mcg amount is clearly disclosed and sits within a clinically used range. The softgel is practical, but its lipid carrier, branded source, and all-trans purity are not identified.

Study evidence
Vitamin K Supportive 78 studies
Anti-Aging
Anti-Aging
Impact
Highest effect
B Goal FitA- Strength of SupportC- CoverageA Formula Quality
Vitamin K · 180 mcg

MK-7 supports vitamin K-dependent proteins that maintain bone and vascular integrity with age. The focused softgel provides a strong maintenance amount without unrelated ingredients.

The label clearly names MK-7, but the source, isomer purity, and carrier oil are not supplied. MK-7 can oppose warfarin's action, making consistent intake and clinician-guided monitoring important for anticoagulant users.

Study evidence
Vitamin K Supportive 27 studies
Cardiovascular Support
Cardiovascular Support
Impact
Highest effect
B+ Goal FitA Strength of SupportD+ CoverageA Formula Quality
Vitamin K · 180 mcg

Vitamin K2 as MK-7 supports proper calcium placement and is directly relevant to long-term vascular integrity. The 180 mcg amount is substantial and clearly disclosed.

The source lacks an all-trans purity claim, and the oil carrier is not identified, leaving some quality details unresolved. MK-7 can oppose warfarin-type anticoagulants, so people using one need consistent vitamin K intake and prescriber-directed dose management.

Study evidence
Vitamin K Supportive 40 studies

Ingredients

IngredientAmount per serving
Vitamin K2 (Menaquinone-7)
 180 mcg
Gluten Free Adults 18–50 Women
Report overview
Vitamin K (Menaquinone-7) · 180 mcg OverallScore86
B- Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyB+ Value

The MK-7 form and 180 mcg dose are well aligned with effective vitamin K2 use. The generic source lacks a branded or all-trans purity claim, and the softgel carrier is not identified. Cost per serving is close to the collection norm, providing solid value for the dose.

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87 Performance

Vitamin K2 100 mcg

SR Sports Research
<p>The formula provides 100 mcg of Vitamin K2 (Menaquinone-7), which may be a better fit than the original’s 180 mcg of Vitamin K2 (Menaquinone-7) when its specific vitamin K form and companion nutrients are preferred. Vitamin K may interfere with warfarin-type anticoagulants, so people using them need clinician-directed intake.</p>
86 Performance

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<p>The formula provides 90 mcg of Vitamin K2 (Menaquinone-7), which may be a better fit than the original’s 180 mcg of Vitamin K2 (Menaquinone-7) when its specific vitamin K form and companion nutrients are preferred. Vitamin K may interfere with warfarin-type anticoagulants, so people using them need clinician-directed intake.</p>
87 Performance

Vitamin K2 as MK-7 100 mcg

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<p>The formula provides 100 mcg of Vitamin K2 (Menaquinone-7), which may be a better fit than the original’s 180 mcg of Vitamin K2 (Menaquinone-7) when its specific vitamin K form and companion nutrients are preferred. Vitamin K may interfere with warfarin-type anticoagulants, so people using them need clinician-directed intake.</p>
88 Budget

Vitamin K2 MK-7 100 mcg

Nutricost
<p>At a lower recurring cost, the formula provides 100 mcg of Vitamin K (Menaquinone-7), making it a practical budget alternative to the original’s 180 mcg of Vitamin K2 (Menaquinone-7). Vitamin K may interfere with warfarin-type anticoagulants, so people using them need clinician-directed intake.</p>
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MK-7 Vitamin K-2 100 mcg

NOW
<p>At a lower recurring cost, the formula provides 100 mcg of Vitamin K2 (Menaquinone-7), making it a practical budget alternative to the original’s 180 mcg of Vitamin K2 (Menaquinone-7). Vitamin K may interfere with warfarin-type anticoagulants, so people using them need clinician-directed intake.</p>
85 Budget

Vitamin K2 MenaQ7 100 mcg

AN Amazing Nutrition Amazing Formulas
<p>At a lower recurring cost, the formula provides 100 mcg of Vitamin K2 (Natto), making it a practical budget alternative to the original’s 180 mcg of Vitamin K2 (Menaquinone-7). Vitamin K may interfere with warfarin-type anticoagulants, so people using them need clinician-directed intake.</p>
86 Value

Vitamins D3 2500 IU (62.5 mcg) & K2 120 mcg

NaturesPlus
<p>The formula combines 120 mcg of Vitamin K2 (Menaquinone-7) and 62.50 mcg of Vitamin D3 (Cholecalciferol) with favorable serving value, which may offer a better quality-to-cost balance than the original’s 180 mcg of Vitamin K2 (Menaquinone-7). Vitamin K may interfere with warfarin-type anticoagulants, so people using them need clinician-directed intake.</p>
87 Value

MK-7 Vitamin K-2 100 mcg

NOW
<p>The formula combines 100 mcg of Vitamin K-2 (Menaquinone-7) with favorable serving value, which may offer a better quality-to-cost balance than the original’s 180 mcg of Vitamin K2 (Menaquinone-7). Vitamin K may interfere with warfarin-type anticoagulants, so people using them need clinician-directed intake.</p>
86 Value

Vitamin K2 100 mcg + Vitamin D3 125 mcg

Nutricost
<p>The formula combines 100 mcg of Vitamin K (Menaquinone-7) and 125 mcg of Vitamin D (Cholecalciferol) with favorable serving value, which may offer a better quality-to-cost balance than the original’s 180 mcg of Vitamin K2 (Menaquinone-7). The high vitamin D amount warrants attention to total intake, and vitamin K may interfere with warfarin-type anticoagulants.</p>
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Three-year low-dose menaquinone-7 supplementation helps decrease bone loss in healthy postmenopausal women.
    Knapen MH; Drummen NE; Smit E; Vermeer C; Theuwissen E · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2014
    Randomized trial244 participantsBone Health forVitamin K
  2. Does vitamin K2 play a role in the prevention and treatment of osteoporosis for postmenopausal women: a meta-analysis of randomized controlled trials.
    Huang ZB; Wan SL; Lu YJ; Ning L; Liu C; Fan SW · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2015
    Meta-analysis6,759 participants19 studies pooledBone Health forVitamin K
  3. Investigating the interrelationship of vitamin K and vitamin D status on bone density: results from the VITamin D and OmegA-3 TriaL.
    Chou SH; Booth SL; Cook NR; Kim E; Kotler G; Fu X; Buring JE; Manson JE; LeBoff MS · JBMR plus · 2026
    Randomized trial771 participantsBone Health forVitamin K
  4. Comparison of concurrent treatment with vitamin K2 and risedronate compared with treatment with risedronate alone in patients with osteoporosis: Japanese Osteoporosis Intervention Trial-03.
    Tanaka S; Miyazaki T; Uemura Y; Miyakawa N; Gorai I; Nakamura T; Fukunaga M; Ohashi Y; Ohta H; Mori S; Hagino H; Hosoi T; Sugimoto T; Itoi E; Orimo H; Shiraki M · Journal of bone and mineral metabolism · 2018
    Randomized trial1,874 participantsBone Health forVitamin K
  5. Efficacy and safety of vitamin K2 for postmenopausal women with osteoporosis at a long-term follow-up: meta-analysis and systematic review.
    Zhou M; Han S; Zhang W; Wu D · Journal of bone and mineral metabolism · 2022
    Meta-analysis6,853 participants9 studies pooledBone Health forVitamin K
  6. Menaquinone-7 supplementation improves arterial stiffness in healthy postmenopausal women. A double-blind randomised clinical trial.
    Knapen MH; Braam LA; Drummen NE; Bekers O; Hoeks AP; Vermeer C · Thrombosis and haemostasis · 2016
    Randomized trial244 participantsCardiovascular Support Heart Health forVitamin K
  7. Effects of One-Year Menaquinone-7 Supplementation on Vascular Stiffness and Blood Pressure in Post-Menopausal Women.
    de Vries F; Bittner R; Maresz K; Machuron F; Gåserød O; Jeanne JF; Schurgers LJ · Nutrients · 2025
    Randomized trial165 participantsCardiovascular Support forVitamin K
  8. Vitamin K Intake and Atherosclerotic Cardiovascular Disease in the Danish Diet Cancer and Health Study.
    Bellinge JW; Dalgaard F; Murray K; Connolly E; Blekkenhorst LC; Bondonno CP; Lewis JR; Sim M; Croft KD; Gislason G; Torp-Pedersen C; Tjønneland A; Overvad K; Hodgson JM; Schultz C; Bondonno NP · Journal of the American Heart Association · 2021
    Cohort study53,372 participantsCardiovascular Support Heart Health forVitamin K
  9. Interventions to Attenuate Cardiovascular Calcification Progression: A Systematic Review of Randomized Clinical Trials.
    Murali S; Smith ER; Tiong MK; Tan SJ; Toussaint ND · Journal of the American Heart Association · 2024
    Systematic review9,901 participants49 studies pooledCardiovascular Support forVitamin K
  10. Intake of dietary phylloquinone and menaquinones and risk of stroke.
    Vissers LE; Dalmeijer GW; Boer JM; Monique Verschuren WM; van der Schouw YT; Beulens JW · Journal of the American Heart Association · 2014
    Cohort study35,476 participantsCardiovascular Support forVitamin K
  11. Circulating uncarboxylated matrix Gla protein, a marker of vitamin K status, as a risk factor of cardiovascular disease.
    van den Heuvel EG; van Schoor NM; Lips P; Magdeleyns EJ; Deeg DJ; Vermeer C; den Heijer M · Maturitas · 2014
    Cohort study577 participantsCardiovascular Support forVitamin K
  12. Vitamin K status, cardiovascular disease, and all-cause mortality: a participant-level meta-analysis of 3 US cohorts.
    Shea MK; Barger K; Booth SL; Matuszek G; Cushman M; Benjamin EJ; Kritchevsky SB; Weiner DE · The American journal of clinical nutrition · 2020
    Meta-analysis3,891 participants3 studies pooledAnti-Aging General Health forVitamin K
  13. Topical Menaquinone‑7 (Vitamin K2, MK-7) as a Mitochondrial Bioenergetic Activator for Skin Anti-Aging: Mechanistic Evidence in Skin Cells and a Randomized Split-Face/Neck Study.
    Huang H; Wei R; Xu C; Liu C; Zhao S; Li Y; Wang M · ACS omega · 2026
    Randomized trial30 participantsAnti-Aging forVitamin K
  14. Vitamin K status and cognitive function in healthy older adults.
    Presse N; Belleville S; Gaudreau P; Greenwood CE; Kergoat MJ; Morais JA; Payette H; Shatenstein B; Ferland G · Neurobiology of aging · 2014
    Cross-sectional study320 participantsAnti-Aging forVitamin K
  15. High dephospho-uncarboxylated matrix Gla protein concentrations, a plasma biomarker of vitamin K, in relation to frailty: the Longitudinal Aging Study Amsterdam.
    Machado-Fragua MD; Hoogendijk EO; Struijk EA; Rodriguez-Artalejo F; Lopez-Garcia E; Beulens JW; van Ballegooijen AJ · European journal of nutrition · 2021
    Cohort study644 participantsAnti-Aging forVitamin K
  16. Vitamin K Concentration and Cognitive Status in Elderly Patients on Anticoagulant Therapy: A Pilot Study.
    Alisi L; Cafolla C; Gentili A; Tartaglione S; Curini R; Cafolla A · Journal of aging research · 2022
    Cross-sectional study85 participantsAnti-Aging forVitamin K
  17. Vitamin K and the prevention of fractures: systematic review and meta-analysis of randomized controlled trials.
    Cockayne S; Adamson J; Lanham-New S; Shearer MJ; Gilbody S; Torgerson DJ · Archives of internal medicine · 2006
    Meta-analysis13 studies pooledBone Health forVitamin K
  18. Effect of combined administration of vitamin D3 and vitamin K2 on bone mineral density of the lumbar spine in postmenopausal women with osteoporosis.
    Iwamoto J; Takeda T; Ichimura S · Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association · 2001
    Randomized trial92 participantsBone Health forVitamin K
  19. Low-dose vitamin K2 (MK-4) supplementation for 12 months improves bone metabolism and prevents forearm bone loss in postmenopausal Japanese women.
    Koitaya N; Sekiguchi M; Tousen Y; Nishide Y; Morita A; Yamauchi J; Gando Y; Miyachi M; Aoki M; Komatsu M; Watanabe F; Morishita K; Ishimi Y · Journal of bone and mineral metabolism · 2015
    Randomized trial48 participantsBone Health forVitamin K
  20. Dietary Vitamin K1 Intake and Incident Aortic Valve Stenosis.
    Schultz CJ; Dalgaard F; Bellinge JW; Murray K; Sim M; Connolly E; Blekkenhorst LC; Bondonno CP; Lewis JR; Gislason GH; Tjønneland A; Overvad K; Hodgson JM; Bondonno NP · Arteriosclerosis, thrombosis, and vascular biology · 2024
    Cohort study55,545 participantsCardiovascular Support Heart Health forVitamin K
  21. Association between vitamin K1 intake and mortality in the Danish Diet, Cancer, and Health cohort.
    Palmer CR; Bellinge JW; Dalgaard F; Sim M; Murray K; Connolly E; Blekkenhorst LC; Bondonno CP; Croft KD; Gislason G; Tjønneland A; Overvad K; Schultz C; Lewis JR; Hodgson JM; Bondonno NP · European journal of epidemiology · 2021
    Cohort study56,048 participantsCardiovascular Support Heart Health forVitamin K
  22. Dietary vitamin K intake associates with reduced all-cause mortality in non-alcoholic fatty liver disease patients.
    Huang Y; Zhu X; Han L; Hu H · Scientific reports · 2025
    Cohort study7,857 participantsGeneral Health forVitamin K
  23. The Effect of Topical Vitamin K1 on the Treatment of Cetuximab-Induced Skin Rashes in Metastatic Colorectal Cancer Patients.
    Roayaei M; Rezaei M; Najafizade N · Advanced biomedical research · 2024
    Randomized trial49 participantsGeneral Health forVitamin K
  24. Effect of vitamin K on improving post‑kidney transplant outcomes: a meta‑analysis.
    Sun Z; Zhu K; Liang G; Yan F; Chao S; Jia L; Niu Y · Experimental and therapeutic medicine · 2023
    Meta-analysis7 studies pooledGeneral Health forVitamin K
  25. Vitamin K1 intake is associated with lower risk for all-cause and cardiovascular disease mortality in community-dwelling older Australian women.
    Dupuy M; Radavelli-Bagatini S; Zhong L; Dalla Via J; Zhu K; Blekkenhorst LC; Bondonno NP; Linneberg A; Bellinge JW; Schultz C; Courtney W; Prince RL; Hodgson JM; Lewis JR; Sim M · Nutrition, metabolism, and cardiovascular diseases : NMCD · 2024
    Cohort study1,436 participantsGeneral Health forVitamin K
  26. The effect of vitamin K1 on arterial calcification activity in subjects with diabetes mellitus: a post hoc analysis of a double-blind, randomized, placebo-controlled trial.
    Bellinge JW; Francis RJ; Lee SC; Bondonno NP; Sim M; Lewis JR; Watts GF; Schultz CJ · The American journal of clinical nutrition · 2022
    Randomized trial149 participantsHeart Health forVitamin K