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Calcium with Vitamins D3 & K2

4.8
★ ★ ★ ★ ★
(424 ratings)
Vitamin K 180 mcg
Product Image
Score73
A coherent but high-intensity bone formula with substantial MK-7 and D3, limited by excessive routine vitamin D, calcium carbonate, and high cost.
How scoring works
Capsule
Quantity:30 Capsule(s) • (30 servings)
Goals:
Bone Health
General Health
Heart Health
Anti-Aging
Cardiovascular Support

Score 73

A coherent but high-intensity bone formula with substantial MK-7 and D3, limited by excessive routine vitamin D, calcium carbonate, and high cost.
How scoring works

Also available as

1 option
90 servings K 180 mcg • 90 Capsule(s) • 90 servings $93.50 ($1.03 per serving)
$31.98($1.06 per serving)
Vitacost
$ 39.95
iHerb
$ 35.17
Pure Formulas
$ 31.98
Report prices

Analysis

MK-7 and vitamin D3 provide strong regulation of calcium absorption and placement, while calcium carbonate supplies a smaller structural-mineral contribution. All forms and amounts are clearly stated.

The vitamin D amount is high for everyday use without documented need, and calcium carbonate is less flexible than some alternatives. Generic MK-7 in a dry capsule offers no premium source or lipid-delivery advantage.

The formula fits adults with a monitored need for high vitamin D and a compact bone-support combination. It is a poor match for casual maintenance because of the vitamin D exposure and high serving cost.

Who is it for
  • Adults with a clinician-monitored high-vitamin-D need
  • Users seeking combined calcium regulators
  • People wanting a compact bone-focused formula
Best for
  • Monitored bone-support routines
  • Calcium absorption and placement
  • High-depth D3 and K2 supplementation

Pros

  • Substantial MK-7 amount
  • Vitamin D3 is a logical partner
  • All active amounts are clear

Cons

  • Vitamin D exceeds the usual adult daily upper level
  • Calcium carbonate is less favorable for some users
  • High serving cost

Warnings

  • High vitamin D can raise blood calcium with long-term unsupervised use
  • MK-7 can oppose warfarin and related vitamin K antagonist medicines
  • People prone to hypercalcemia or kidney stones need individualized guidance
  • Account for calcium and vitamin D from other supplements

Nutrient quality

80 High impact

Menaquinone-7 and vitamin D3 are well-regarded, while calcium carbonate is an ordinary form, and vitamin K2 and vitamin D3 are substantial, while calcium is modest. The high vitamin D3 amount may raise calcium levels when combined with other vitamin D or in susceptible users, while the focused formula avoids low-value active extras.

Ingredient transparency

84 Highest impact

Specific amounts are listed for every supplied active ingredient. No proprietary blend hides active doses, while capsule, softgel, or tablet excipients are not included in the supplied details.

Customer satisfaction

70 High impact

The supplied aggregate satisfaction metric is very strong, and the feedback volume is sufficient for a reasonably stable aggregate metric. No review excerpts were provided, so recurring complaints and purpose-specific experiences cannot be checked.

Value for money

51 Moderate impact

Strong vitamin forms help, but high vitamin D, modest calcium, and a high serving cost weaken value. The serving is relatively costly for a small three-active formula, while the formula avoids unnecessary extras.

Report analysis

Goals

Bone Health
Bone Health
Impact
Highest effect
A- Goal FitA- Strength of SupportC+ CoverageA+ Formula Quality
Vitamin K · 180 mcgCalcium · 180 mgVitamin D · 125 mcg

Vitamin D3 and MK-7 strongly support calcium absorption and placement, while 180 mg calcium adds only a small amount of structural mineral. The regulator-focused combination is relevant to bone health but depends heavily on dietary calcium and magnesium.

Forms and amounts are clearly disclosed, with a strong MK-7 serving and a high D3 amount. Long-term use of 5,000 IU D3 without monitoring may raise calcium excessively in susceptible users, and MK-7 can oppose warfarin.

Study evidence
Calcium Supportive 144 studies
Vitamin D Supportive 202 studies
Vitamin K Supportive 78 studies
General Health
General Health
Impact
Highest effect
A- Goal FitB- Strength of SupportB CoverageA Formula Quality
Vitamin D · 125 mcgVitamin K · 180 mcg

The combination is logically built around calcium handling, with vitamin D3 supporting absorption and MK-7 helping direct calcium use. Its benefits are most relevant to bone and calcium metabolism rather than broad coverage of general wellness.

Ingredient forms and amounts are clearly listed, though calcium carbonate is less favorable for absorption than some alternatives. Vitamin D3 at 125 mcg exceeds the adult daily upper limit, and MK-7 can interfere with warfarin and related vitamin K antagonists.

Study evidence
Vitamin D Supportive 115 studies
Vitamin K Supportive 34 studies
Heart Health
Heart Health
Impact
Highest effect
B+ Goal FitA Strength of SupportC CoverageA- Formula Quality
Vitamin K · 180 mcgVitamin D · 125 mcg

Vitamin K2 as MK-7 and vitamin D3 form a logical calcium-management combination relevant to arterial health. The 180 mcg MK-7 amount is substantial, while the 125 mcg vitamin D3 amount is high for routine unsupervised use.

Calcium adds bone-mineral support but makes the formula less focused on cardiovascular needs. MK-7 directly opposes warfarin, and prolonged high-dose vitamin D3 may raise calcium levels, so users of vitamin K antagonists or people prone to hypercalcemia need clinical oversight.

Study evidence
Vitamin D Mixed 164 studies
Vitamin K Mixed 62 studies
Anti-Aging
Anti-Aging
Impact
High effect
B- Goal FitB+ Strength of SupportC+ CoverageA Formula Quality
Vitamin K · 180 mcgVitamin D · 125 mcg

MK-7, vitamin D3, and calcium form a coherent strategy for bone structure and calcium placement. The two vitamins are meaningfully supplied, while calcium provides a smaller supporting amount.

The dry capsule and calcium carbonate form limit delivery quality, and the formula does not address wider aging mechanisms. MK-7 can interfere with warfarin and related vitamin K antagonists, making consistent clinician-managed vitamin K intake important for users of those medicines.

Study evidence
Vitamin D Supportive 50 studies
Vitamin K Supportive 27 studies
Cardiovascular Support
Cardiovascular Support
Impact
High effect
B Goal FitB Strength of SupportC- CoverageA Formula Quality
Vitamin K · 180 mcgVitamin D · 125 mcg

Vitamin D3 and MK-7 form a logical calcium-management pair with potential relevance to vascular and bone health. The addition of calcium makes the product less specifically cardiovascular, and benefits depend on nutritional status.

The 180 mcg MK-7 amount is well aligned, while the 125 mcg vitamin D3 amount is above the usual adult daily upper intake level. MK-7 can oppose warfarin and related vitamin K antagonists, so users of those medicines need medically managed and consistent vitamin K intake.

Study evidence
Vitamin K Supportive 40 studies

Ingredients

IngredientAmount per serving
Vitamin D3 (Cholecalciferol)
 125 mcg
Vitamin K2 (Menaquinone-7)
 180 mcg
Calcium (Calcium Carbonate)
 180 mg
Adults 18–50
Report overview
Vitamin K (Menaquinone-7) · 180 mcg OverallScore77
C+ Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyD+ Value

The capsule provides a well-aligned MK-7 amount together with vitamin D3 and calcium. Its generic MK-7 source and dry delivery limit quality, while the high serving cost weakens value despite the added nutrients. MK-7 can interfere with warfarin and related vitamin K antagonists, so users of those medicines need managed, consistent vitamin K intake.

View ingredientView products
Loading alternative details
86 Performance

Vitamins D3 1000 IU (25 mcg) & K2 100 mcg

NaturesPlus
Compared with 125 mcg of vitamin D3 with 180 mcg of MK-7 vitamin K2, the alternative provides 25 mcg of vitamin D3 with 100 mcg of MK-7 vitamin K2, and the supplied analysis indicates stronger alignment with the Vitamin K collection. Its dry capsule lacks a lipid carrier, and MK-7 requires consistent intake for people using warfarin.
87 Performance

Vitamin D3 25 mcg (1000 IU) & K2 120 mcg

Natural Factors
Compared with 125 mcg of vitamin D3 with 180 mcg of MK-7 vitamin K2, the alternative provides 25 mcg of vitamin D3 with 120 mcg of MK-7 vitamin K2, and the supplied analysis indicates stronger alignment with the Vitamin K collection. Duplicate K2 source entries create minor label ambiguity, though the softgel and strong value are practical strengths.
88 Performance

D3 + K2 Green Apple

EZ Melts
Compared with 125 mcg of vitamin D3 with 180 mcg of MK-7 vitamin K2, the alternative provides 125 mcg of vitamin D3 with 120 mcg of MK-7 vitamin K2, and the supplied analysis indicates stronger alignment with the Vitamin K collection. High vitamin D and absent fat-based delivery guidance are the main limitations, while value is favorable.
88 Budget

Vitamin K2 MK-7 100 mcg

Nutricost
The supplied serving cost is lower, while the formula provides 100 mcg of MK-7 vitamin K2. Vitamin K2 can interfere with warfarin-type anticoagulants.
89 Budget

Mega D-3 5000 IU & MK-7 180 mcg

NOW
The supplied serving cost is lower, while the formula provides 125 mcg of vitamin D3 with 180 mcg of MK-7 vitamin K2. High vitamin D remains the main dosing limitation, while the dry capsule lacks stated fat-intake guidance.
85 Budget

Vitamin K2 MenaQ7 100 mcg

AN Amazing Nutrition Amazing Formulas
The supplied serving cost is lower, while the formula provides vitamin k2. Its vitamin K can counteract warfarin and related vitamin K antagonists, so people using those medicines need clinician-directed intake.
86 Value

Vitamins D3 2500 IU (62.5 mcg) & K2 120 mcg

NaturesPlus
62.5 mcg of vitamin D3 with 120 mcg of MK-7 vitamin K2 offers a practical value trade-off because the supplied serving cost is lower and the value analysis is stronger. Its dry tablet lacks a lipid carrier, and MK-7 requires consistent intake for people using warfarin.
86 Value

Vitamin K2 100 mcg + Vitamin D3 125 mcg

Nutricost
125 mcg of vitamin D3 with 100 mcg of MK-7 vitamin K2 offers a practical value trade-off because the supplied serving cost is lower and the value analysis is stronger. Vitamin K2 can interfere with warfarin-type anticoagulants.
87 Value

MK-7 Vitamin K-2 100 mcg

NOW
100 mcg of MK-7 vitamin K2 offers a practical value trade-off because the supplied serving cost is lower and the value analysis is stronger. Its long supply supports strong value, though vitamin K can conflict with warfarin and similar vitamin K antagonists.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Three-year low-dose menaquinone-7 supplementation helps decrease bone loss in healthy postmenopausal women.
    Knapen MH; Drummen NE; Smit E; Vermeer C; Theuwissen E · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2014
    Randomized trial244 participantsBone Health forVitamin K
  2. Investigating the interrelationship of vitamin K and vitamin D status on bone density: results from the VITamin D and OmegA-3 TriaL.
    Chou SH; Booth SL; Cook NR; Kim E; Kotler G; Fu X; Buring JE; Manson JE; LeBoff MS · JBMR plus · 2026
    Randomized trial771 participantsBone Health forVitamin K
  3. Efficacy and safety of vitamin K2 for postmenopausal women with osteoporosis at a long-term follow-up: meta-analysis and systematic review.
    Zhou M; Han S; Zhang W; Wu D · Journal of bone and mineral metabolism · 2022
    Meta-analysis6,853 participants9 studies pooledBone Health forVitamin K
  4. Joint association of serum 25-hydroxyvitamin D concentration and body mass index on the acceleration of clinical biomarker-based biological aging.
    Pan Z; Zeng J; Chen Z; Chen S; Yang J; Li H; Wang S; Wang J; Li N; Gong Y; Liu M; Li C · The journals of gerontology. Series A, Biological sciences and medical sciences · 2026
    Cohort study389,217 participantsAnti-Aging forVitamin D
  5. Serum 25-Hydroxyvitamin D Levels as an Aging Marker: Strong Associations With Age and All-Cause Mortality Independent From Telomere Length, Epigenetic Age Acceleration, and 8-Isoprostane Levels.
    Schöttker B; Hagen L; Zhang Y; Gào X; Holleczek B; Gao X; Brenner H · The journals of gerontology. Series A, Biological sciences and medical sciences · 2019
    Cohort study9,940 participantsAnti-Aging forVitamin D
  6. Sex-specific associations of serum 25-hydroxyvitamin D concentrations with incident sarcopenia in older adults: A 2-year follow-up study.
    Song S; Lim JY; Kim M; Won CW; Park HY · The journal of nutrition, health & aging · 2025
    Cohort study1,292 participantsAnti-Aging forVitamin D
  7. Vitamin D deficit is associated with accelerated brain aging in the general population.
    Terock J; Bonk S; Frenzel S; Wittfeld K; Garvert L; Hosten N; Nauck M; Völzke H; Van der Auwera S; Grabe HJ · Psychiatry research. Neuroimaging · 2022
    Cross-sectional study1,865 participantsAnti-Aging forVitamin D
  8. Vitamin D intake is associated with dementia risk in the Washington Heights-Inwood Columbia Aging Project (WHICAP).
    Zhao C; Tsapanou A; Manly J; Schupf N; Brickman AM; Gu Y · Alzheimer's & dementia : the journal of the Alzheimer's Association · 2021
    Cohort study1,759 participantsAnti-Aging forVitamin D
  9. Vitamin K status, cardiovascular disease, and all-cause mortality: a participant-level meta-analysis of 3 US cohorts.
    Shea MK; Barger K; Booth SL; Matuszek G; Cushman M; Benjamin EJ; Kritchevsky SB; Weiner DE · The American journal of clinical nutrition · 2020
    Meta-analysis3,891 participants3 studies pooledAnti-Aging General Health forVitamin K
  10. Topical Menaquinone‑7 (Vitamin K2, MK-7) as a Mitochondrial Bioenergetic Activator for Skin Anti-Aging: Mechanistic Evidence in Skin Cells and a Randomized Split-Face/Neck Study.
    Huang H; Wei R; Xu C; Liu C; Zhao S; Li Y; Wang M · ACS omega · 2026
    Randomized trial30 participantsAnti-Aging forVitamin K
  11. Vitamin K status and cognitive function in healthy older adults.
    Presse N; Belleville S; Gaudreau P; Greenwood CE; Kergoat MJ; Morais JA; Payette H; Shatenstein B; Ferland G · Neurobiology of aging · 2014
    Cross-sectional study320 participantsAnti-Aging forVitamin K
  12. High dephospho-uncarboxylated matrix Gla protein concentrations, a plasma biomarker of vitamin K, in relation to frailty: the Longitudinal Aging Study Amsterdam.
    Machado-Fragua MD; Hoogendijk EO; Struijk EA; Rodriguez-Artalejo F; Lopez-Garcia E; Beulens JW; van Ballegooijen AJ · European journal of nutrition · 2021
    Cohort study644 participantsAnti-Aging forVitamin K
  13. Vitamin K Concentration and Cognitive Status in Elderly Patients on Anticoagulant Therapy: A Pilot Study.
    Alisi L; Cafolla C; Gentili A; Tartaglione S; Curini R; Cafolla A · Journal of aging research · 2022
    Cross-sectional study85 participantsAnti-Aging forVitamin K
  14. What is the impact of daily oral supplementation of vitamin D3 (cholecalciferol) plus calcium on the incidence of hip fracture in older people? A systematic review and meta-analysis.
    Manoj P; Derwin R; George S · International journal of older people nursing · 2023
    Meta-analysis12,620 participants7 studies pooledBone Health forCalcium
  15. Calcium supplementation prevents seasonal bone loss and changes in biochemical markers of bone turnover in elderly New England women: a randomized placebo-controlled trial.
    Storm D; Eslin R; Porter ES; Musgrave K; Vereault D; Patton C; Kessenich C; Mohan S; Chen T; Holick MF; Rosen CJ · The Journal of clinical endocrinology and metabolism · 1998
    Randomized trial60 participantsBone Health forCalcium
  16. The effects of calcium supplementation (milk powder or tablets) and exercise on bone density in postmenopausal women.
    Prince R; Devine A; Dick I; Criddle A; Kerr D; Kent N; Price R; Randell A · Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 1995
    Randomized trial168 participantsBone Health forCalcium
  17. The efficacy of calcium supplementation alone in elderly Thai women over a 2-year period: a randomized controlled trial.
    Rajatanavin R; Chailurkit L; Saetung S; Thakkinstian A; Nimitphong H · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2014
    Randomized trial404 participantsBone Health forCalcium
  18. Calcium-enriched foods and bone mass growth in prepubertal girls: a randomized, double-blind, placebo-controlled trial.
    Bonjour JP; Carrie AL; Ferrari S; Clavien H; Slosman D; Theintz G; Rizzoli R · The Journal of clinical investigation · 1997
    Randomized trial149 participantsBone Health forCalcium
  19. Pregnancy vitamin D supplementation and offspring bone mineral density in childhood follow-up of a randomized controlled trial.
    Moon RJ; D' Angelo S; Curtis EM; Ward KA; Crozier SR; Schoenmakers I; Javaid MK; Bishop NJ; Godfrey KM; Cooper C; Harvey NC; MAVIDOS Trial Group · The American journal of clinical nutrition · 2024
    Randomized trial454 participantsBone Health forVitamin D
  20. Vitamin D analogs and bone: preclinical and clinical studies with eldecalcitol.
    Matsumoto T; Takano T; Saito H; Takahashi F · BoneKEy reports · 2014
    Narrative reviewBone Health forVitamin D
  21. Efficacy of vitamin D fortified foods on bone mineral density and serum bone biomarkers: A systematic review and meta-analysis of interventional studies.
    Tangestani H; Djafarian K; Emamat H; Arabzadegan N; Shab-Bidar S · Critical reviews in food science and nutrition · 2020
    Meta-analysis1,786 participants20 studies pooledBone Health forVitamin D
  22. Cholecalciferol Supplementation Attenuates Bone Loss in Incident Kidney Transplant Recipients: A Prespecified Secondary Endpoint Analysis of a Randomized Controlled Trial.
    Tsujita M; Doi Y; Obi Y; Hamano T; Tomosugi T; Futamura K; Okada M; Hiramitsu T; Goto N; Isaka Y; Takeda A; Narumi S; Watarai Y · Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2022
    Randomized trial193 participantsBone Health forVitamin D
  23. Vitamin D supplementation and bone health in post-menopausal women: a 24-month randomized controlled intervention with enhanced bioavailability formulations.
    Rasool N; Munir Y · European journal of clinical nutrition · 2026
    Randomized trial612 participantsBone Health forVitamin D
  24. Vitamin K and the prevention of fractures: systematic review and meta-analysis of randomized controlled trials.
    Cockayne S; Adamson J; Lanham-New S; Shearer MJ; Gilbody S; Torgerson DJ · Archives of internal medicine · 2006
    Meta-analysis13 studies pooledBone Health forVitamin K
  25. Effect of combined administration of vitamin D3 and vitamin K2 on bone mineral density of the lumbar spine in postmenopausal women with osteoporosis.
    Iwamoto J; Takeda T; Ichimura S · Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association · 2001
    Randomized trial92 participantsBone Health forVitamin K
  26. Low-dose vitamin K2 (MK-4) supplementation for 12 months improves bone metabolism and prevents forearm bone loss in postmenopausal Japanese women.
    Koitaya N; Sekiguchi M; Tousen Y; Nishide Y; Morita A; Yamauchi J; Gando Y; Miyachi M; Aoki M; Komatsu M; Watanabe F; Morishita K; Ishimi Y · Journal of bone and mineral metabolism · 2015
    Randomized trial48 participantsBone Health forVitamin K
  27. Vitamin K Intake and Atherosclerotic Cardiovascular Disease in the Danish Diet Cancer and Health Study.
    Bellinge JW; Dalgaard F; Murray K; Connolly E; Blekkenhorst LC; Bondonno CP; Lewis JR; Sim M; Croft KD; Gislason G; Torp-Pedersen C; Tjønneland A; Overvad K; Hodgson JM; Schultz C; Bondonno NP · Journal of the American Heart Association · 2021
    Cohort study53,372 participantsCardiovascular Support Heart Health forVitamin K
  28. Menaquinone-7 supplementation improves arterial stiffness in healthy postmenopausal women. A double-blind randomised clinical trial.
    Knapen MH; Braam LA; Drummen NE; Bekers O; Hoeks AP; Vermeer C · Thrombosis and haemostasis · 2016
    Randomized trial244 participantsCardiovascular Support Heart Health forVitamin K
  29. Effects of One-Year Menaquinone-7 Supplementation on Vascular Stiffness and Blood Pressure in Post-Menopausal Women.
    de Vries F; Bittner R; Maresz K; Machuron F; Gåserød O; Jeanne JF; Schurgers LJ · Nutrients · 2025
    Randomized trial165 participantsCardiovascular Support forVitamin K
  30. Dietary Vitamin K1 Intake and Incident Aortic Valve Stenosis.
    Schultz CJ; Dalgaard F; Bellinge JW; Murray K; Sim M; Connolly E; Blekkenhorst LC; Bondonno CP; Lewis JR; Gislason GH; Tjønneland A; Overvad K; Hodgson JM; Bondonno NP · Arteriosclerosis, thrombosis, and vascular biology · 2024
    Cohort study55,545 participantsCardiovascular Support Heart Health forVitamin K
  31. Association between vitamin K1 intake and mortality in the Danish Diet, Cancer, and Health cohort.
    Palmer CR; Bellinge JW; Dalgaard F; Sim M; Murray K; Connolly E; Blekkenhorst LC; Bondonno CP; Croft KD; Gislason G; Tjønneland A; Overvad K; Schultz C; Lewis JR; Hodgson JM; Bondonno NP · European journal of epidemiology · 2021
    Cohort study56,048 participantsCardiovascular Support Heart Health forVitamin K
  32. Vitamin D supplementation for prevention of mortality in adults.
    Bjelakovic G; Gluud LL; Nikolova D; Whitfield K; Wetterslev J; Simonetti RG; Bjelakovic M; Gluud C · The Cochrane database of systematic reviews · 2014
    Meta-analysis95,286 participants159 studies pooledGeneral Health forVitamin D
  33. Effect of vitamin D on gastrointestinal symptoms and health-related quality of life in irritable bowel syndrome patients: a randomized double-blind clinical trial.
    Abbasnezhad A; Amani R; Hajiani E; Alavinejad P; Cheraghian B; Ghadiri A · Neurogastroenterology and motility · 2018
    Randomized trial90 participantsGeneral Health forVitamin D
  34. The impact of vitamin D administration on mortality in COVID-19 patients: a systematic review and meta-analysis of randomized controlled trials.
    Kow CS; Ramachandram DS; Hasan SS; Wong Z; Thiruchelvam K · Inflammopharmacology · 2024
    Meta-analysis2,495 participants19 studies pooledGeneral Health forVitamin D
  35. Vitamin D Status and Mortality: A Systematic Review of Observational Studies.
    Heath AK; Kim IY; Hodge AM; English DR; Muller DC · International journal of environmental research and public health · 2019
    Systematic review84 studies pooledGeneral Health forVitamin D
  36. Meta-analysis of long-term vitamin D supplementation on overall mortality.
    Zheng Y; Zhu J; Zhou M; Cui L; Yao W; Liu Y · PloS one · 2014
    Meta-analysis42 studies pooledGeneral Health forVitamin D
  37. Dietary vitamin K intake associates with reduced all-cause mortality in non-alcoholic fatty liver disease patients.
    Huang Y; Zhu X; Han L; Hu H · Scientific reports · 2025
    Cohort study7,857 participantsGeneral Health forVitamin K
  38. The Effect of Topical Vitamin K1 on the Treatment of Cetuximab-Induced Skin Rashes in Metastatic Colorectal Cancer Patients.
    Roayaei M; Rezaei M; Najafizade N · Advanced biomedical research · 2024
    Randomized trial49 participantsGeneral Health forVitamin K
  39. Effect of vitamin K on improving post‑kidney transplant outcomes: a meta‑analysis.
    Sun Z; Zhu K; Liang G; Yan F; Chao S; Jia L; Niu Y · Experimental and therapeutic medicine · 2023
    Meta-analysis7 studies pooledGeneral Health forVitamin K
  40. Vitamin K1 intake is associated with lower risk for all-cause and cardiovascular disease mortality in community-dwelling older Australian women.
    Dupuy M; Radavelli-Bagatini S; Zhong L; Dalla Via J; Zhu K; Blekkenhorst LC; Bondonno NP; Linneberg A; Bellinge JW; Schultz C; Courtney W; Prince RL; Hodgson JM; Lewis JR; Sim M · Nutrition, metabolism, and cardiovascular diseases : NMCD · 2024
    Cohort study1,436 participantsGeneral Health forVitamin K
  41. Vitamin D supplementation for cardiometabolic risk markers in pregnant women based on the gestational diabetes mellitus or obesity status : a randomized clinical trial.
    Yin WJ; Wang P; Ma SS; Tao RX; Hu HL; Jiang XM; Zhang Y; Tao FB; Zhu P · European journal of nutrition · 2024
    Randomized trial1,537 participantsHeart Health forVitamin D
  42. Paricalcitol and endothelial function in chronic kidney disease trial.
    Zoccali C; Curatola G; Panuccio V; Tripepi R; Pizzini P; Versace M; Bolignano D; Cutrupi S; Politi R; Tripepi G; Ghiadoni L; Thadhani R; Mallamaci F · Hypertension (Dallas, Tex. : 1979) · 2015
    Randomized trial88 participantsHeart Health forVitamin D
  43. Vitamin D Supplementation, Serum 25(OH)D Concentrations and Cardiovascular Disease Risk Factors: A Systematic Review and Meta-Analysis.
    Mirhosseini N; Rainsbury J; Kimball SM · Frontiers in cardiovascular medicine · 2020
    Meta-analysis81 studies pooledHeart Health forVitamin D
  44. Does vitamin D supplementation modulate metabolic risk factors of cardiovascular disease? A systematic review and meta-analysis of clinical trials.
    Abumweis S; Alqadi S; Al Tarteer A; Alrefai W; Alzoughool F; Jew S; Qudah T · Asia Pacific journal of clinical nutrition · 2026
    Meta-analysis45 studies pooledHeart Health forVitamin D
  45. Comparative Efficacy of Nutraceuticals on Endothelial Function: A Systematic Review and Network Meta-Analysis.
    Norouzzadeh M; Rashedi MH; Mahdavi-Mazdeh G; Kosari A; Shahinfar H · Current atherosclerosis reports · 2026
    Meta-analysisHeart Health forVitamin D
  46. The effect of vitamin K1 on arterial calcification activity in subjects with diabetes mellitus: a post hoc analysis of a double-blind, randomized, placebo-controlled trial.
    Bellinge JW; Francis RJ; Lee SC; Bondonno NP; Sim M; Lewis JR; Watts GF; Schultz CJ · The American journal of clinical nutrition · 2022
    Randomized trial149 participantsHeart Health forVitamin K