B Complex

B Complex

INNATE Response Formulas4.8 (679 ratings)
Format:Tablet Quantity: 180 Tablet(s) · 180 servings
Goals

Product analysis

64 out of 100

B Complex supports normal energy use and can help tiredness linked to low B-vitamin intake. Missing riboflavin and folate preparation details make close comparisons harder.

AI assessment of the formula, label and price. How scoring works

Nutrient Quality53

Vitamin B1 and B5 have clearly identified usable forms, and the niacin preparation is specified. Several other ingredients have missing preparation details or insufficient quality information.

Ingredient Transparency88

All listed quantities and most forms are disclosed. Riboflavin, folate and kale lack preparation details, limiting precise comparisons.

Value For Money41

Riboflavin compares favorably on serving price. The full serving looks expensive when considered for niacin, vitamin B5 or thiamin, while other value comparisons remain uncertain.

Customer Satisfaction80

Customer feedback is very positive across hundreds of ratings. The review history provides useful satisfaction context without establishing extra energy for adequately nourished adults.

Product Focus67

The main purpose is to cover B-vitamin needs involved in normal energy use. Benefits for tiredness depend on a relevant shortfall, with no established calorie-burning boost from extra intake.

Format
Tablet
Container
180 Tablet(s)
Per serving
$0.43
Customer rating
4.8 · 679 ratings
Report analysis

Goals

Impact
High effect
B+ Ingredient FitF PathwaysB EvidenceA+ Formulation Logic
Vitamin B5 · 45 mgRiboflavin · 9 mgThiamin · 9 mgVitamin B12 · 50 mcg

Folate, Niacin, Vitamin B6, Vitamin B12, Vitamin B5 and Vitamin B2 (Riboflavin) can help reduce tiredness when inadequate intake causes deficiency-related fatigue. B12 and folate support normal red-blood-cell formation; deficiency-related anaemia can cause weakness. These functions do not establish an energy boost when intake is already adequate. The B12 amount falls below the saved comparison threshold, despite its nutritional role.

How this product is rated for Energy

Ingredient fit83

Vitamin B2 (Riboflavin) anchors the recognized ingredient fit, with declared amounts partly meeting the saved comparisons.
Goal fit
Recognized energy-related ingredients share the formula with ingredients serving other goals, reducing its focus.
Dose adequacy
The declared amounts partly meet the saved comparisons, limiting the size of the recognized contribution.

Pathways0

The saved result identifies no coverage of its specific energy pathways. Nutritional fatigue support remains distinct from alertness or exercise capacity.
Depth
No specific energy pathway receives coverage, even though the saved result recognizes nutritional contributions.
Breadth
No energy pathway reaches the saved breadth threshold.

Evidence78

Vitamin B2 (Riboflavin) leads the recognized evidence, but the supplied context limits how broadly its findings apply.
Evidence strength
Vitamin B2 (Riboflavin) supplies the strongest recognized evidence here, subject to the population and application limits described for it.
Studied preparation
The saved findings accept the qualifying preparations; this does not establish form superiority.

Formulation logic100

No required partner is missing, and no configured sedative conflict is present. The recognized amounts reach the saved minimum comparison.
Partner coverage
The recognized ingredients have no missing required partner for their assigned contributions.
Conflicts
No configured sedative conflict applies: valerian, kava, qualifying tryptophan and melatonin are absent.
Effective doses
All recognized ingredients reach the saved minimum amount comparison; that threshold is not proof of a clinical energy effect.
Study evidence
Thiamin Disputed 12 studies
Impact
High effect
B+ Ingredient FitF PathwaysA+ EvidenceA+ Formulation Logic
Biotin · 30 mcgNiacin · 45 mgVitamin B12 · 50 mcgRiboflavin · 9 mgThiamin · 9 mgVitamin B5 · 45 mgVitamin B6 · 10 mg

B vitamins help the body use carbohydrate, fat and protein through normal enzyme and cofactor functions. Supplying more does not establish a rise in resting or daily energy expenditure when intake is adequate. The declared amounts do not demonstrate sustained metabolic-rate or weight-loss effects.

How this product is rated for Metabolism Support

Ingredient fit82

Vitamin B1 (Thiamin) contributes to the saved ingredient and amount findings. The supplied scientific context limits expectations for a direct metabolism boost.
Goal fit
The formula includes ingredients serving other purposes, reducing its specific focus on the included metabolism-related ingredients.
Dose adequacy
Some included amounts provide partial comparison contributions, without establishing how much energy expenditure would change.

Pathways0

Normal nutrient functions remain separate from thermogenesis. No direct energy-expenditure route receives a contribution.
Depth
No direct energy-expenditure route receives a contribution from the supplied findings.
Breadth
No route meets the coverage threshold, leaving limited breadth across energy-expenditure mechanisms.

Evidence100

Vitamin B1 (Thiamin) leads the included evidence finding. Cellular energy roles and metabolic biomarkers do not by themselves demonstrate higher whole-body energy expenditure.
Evidence strength
Vitamin B1 (Thiamin) leads the saved evidence comparison, while its supplied findings do not establish a routine energy-expenditure boost.
Studied preparation
The included preparations are accepted for comparison; this does not establish that the product reproduces a thermogenesis trial.

Formulation logic100

No missing partner or configured conflict is identified. Meeting comparison amounts does not establish added thermogenesis from the formula.
Partner coverage
The supplied findings identify no missing partner needed by the included ingredients.
Conflicts
No configured ingredient conflict is identified in the supplied formula; this is a limited interaction check.
Effective doses
The included ingredients meet the minimum amount threshold, which does not establish an effective thermogenic dose.
Study evidence
Biotin Supportive 5 studies
Niacin Supportive 17 studies
Thiamin Supportive 11 studies
Vitamin B6 Supportive 16 studies

Ingredients

IngredientAmount per servingScore
Thiamine (Thiamine HCl)
9 mg 56
Riboflavin (organic Brown Rice)
9 mg 54
Niacin (Niacinamide, S. cerevisiae)
45 mg 65
Vitamin B6 (Pyridoxine Hydrochloride, S. cerevisiae)
10 mg
Folate
400 mcg DFE
Vitamin B12 (Cyanocobalamin)
50 mcg
Biotin (Brown Rice)
30 mcg
Pantothenic Acid (Calcium D-Pantothenate)
45 mg 61
Kale
125 mg
Gluten Free Adults 18–50 Vegan Kosher Dairy Free Vegetarian
Report overview
A- Active Ingredient Quality & BioavailabilityC+ Dose, Safety & Label TransparencyF Value
Each serving provides 45 mg of niacin as niacinamide. Niacinamide is generally not associated with the typical niacin flush.
How this ingredient is rated

Active Ingredient Quality & Bioavailability86

Niacinamide is a standard form of niacin.
Niacin Form & Goal Alignment
Niacinamide is a standard form used for general niacin intake.
Precursor Source Quality
The recorded source is niacinamide; no advanced precursor claim is recorded in the saved facts.

Dose, Safety & Label Transparency67

The saved facts identify 45 mg of niacin per serving as niacinamide, a form generally not associated with the typical niacin flush.
Clarity of Chemical Form
Niacinamide is identified as the source form.
Form-Specific Dosage Efficacy
The recorded serving contains 45 mg of niacin as niacinamide.
Flush Risk & Safety Labeling
Niacinamide is generally not associated with the typical niacin flush; the saved facts do not record a no-flush claim.

Value20

A whole-product serving costs about $0.43.
Price Per Effective Serving
A whole-product serving costs about $0.43.
B- Active Ingredient Quality & BioavailabilityD+ Dose, Safety & Label TransparencyD- Value
Each serving provides 9 mg of thiamin from thiamine hydrochloride, a relatively small amount for this comparison. At about $4.81 per 100 mg of thiamin, the whole-product price is high for this ingredient.
How this ingredient is rated

Active Ingredient Quality & Bioavailability70

Thiamine Hydrochloride is a standard thiamin form.
Thiamin Chemical Form
Thiamine Hydrochloride is a standard water-soluble form of thiamin.
Excipient Purity
The evaluation does not flag the checked artificial colors or sweeteners, and no minimal-excipient claim is recorded.

Dose, Safety & Label Transparency51

The label lists 9 mg of thiamin per serving, a relatively small amount for this comparison.
Thiamin Dosage Potency
9 mg of thiamin per serving is a relatively small amount for this comparison.
Label Transparency & Proprietary Blends
The label states 9 mg of thiamin per serving.

Value40

The whole-product price is high when compared by the amount of thiamin.
Price per Declared Dose
The whole-product price works out to about $4.81 per 100 mg of thiamin.
A Active Ingredient Quality & BioavailabilityD+ Dose, Safety & Label TransparencyF Value
Each serving supplies 45 mg of vitamin B5 from calcium d-pantothenate, a modest amount in this comparison. The whole-product price is about $4.81 per 500 mg of B5, making it relatively costly for this ingredient.
How this ingredient is rated

Active Ingredient Quality & Bioavailability90

Calcium D-Pantothenate is a named, stable and well-absorbed B5 source.
Vitamin B5 Chemical Form
Calcium D-Pantothenate is a named, stable and well-absorbed B5 source.

Dose, Safety & Label Transparency52

The label names the B5 source and lists 45 mg per serving.
Dosage Potency and Efficacy
The serving lists 45 mg of B5, a modest amount in this comparison.
Label Transparency & Source Clarity
The label names calcium d-pantothenate and lists 45 mg of B5 per serving.

Value20

At about $4.81 per 500 mg of B5, the whole-product price is relatively high for the amount of B5 supplied.
Price per 500mg Vitamin B5
At about $4.81 per 500 mg of B5, the whole-product price is relatively high for the amount of B5 supplied.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Physicochemical properties of and volatile compounds in riboflavin fortified cloudy apple juice; study of its effect on job fatigue among Egyptian construction workers.
    Fouad S; Ibrahim GE; Hussein AMS; Ibrahim FA; El Gendy A · Heliyon · 2021
    Non-randomized trialEnergy forRiboflavin
  2. Vitamin B status in patients with chronic fatigue syndrome.
    Heap LC; Peters TJ; Wessely S · Journal of the Royal Society of Medicine · 1999
    Case-control study30 participantsEnergy forRiboflavin
  3. B-vitamins, related vitamers, and metabolites in patients with quiescent inflammatory bowel disease and chronic fatigue treated with high dose oral thiamine.
    Bager P; Hvas CL; Hansen MM; Ueland P; Dahlerup JF · Molecular medicine (Cambridge, Mass.) · 2023
    Observational studyEnergy forRiboflavin
  4. Metabolic features of chronic fatigue syndrome.
    Naviaux RK; Naviaux JC; Li K; Bright AT; Alaynick WA; Wang L; Baxter A; Nathan N; Anderson W; Gordon E · Proceedings of the National Academy of Sciences of the United States of America · 2024
    Case-control study84 participantsEnergy forRiboflavin
  5. Effectiveness of Riboflavin in Inherited Metabolic Diseases: A Systematic Review
    Bregje Jaeger, Nina N Stolwijk, Femke Aaldering, Charlotte A Ruys, Marije Smits, Nicole I Wolf, Carla E M Hollak, Annet M Bosch · Journal of Inherited Metabolic Disease · 2026
    Systematic review381 studies pooledEnergy Metabolism Support forRiboflavin
  6. Influence of thiamin supplementation on the health and general well-being of an elderly Irish population with marginal thiamin deficiency.
    Smidt LJ; Cremin FM; Grivetti LE; Clifford AJ · Journal of gerontology · 1991
    Randomized trial80 participantsEnergy forThiamin
  7. Randomised clinical trial: high-dose oral thiamine versus placebo for chronic fatigue in patients with quiescent inflammatory bowel disease.
    Bager P; Hvas CL; Rud CL; Dahlerup JF · Alimentary pharmacology & therapeutics · 2021
    Randomized trial40 participantsEnergy forThiamin
  8. Dietary reference values for thiamin.
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA); Turck D; Bresson JL; Burlingame B; Dean T; Fairweather-Tait S; Heinonen M; Hirsch-Ernst KI; Mangelsdorf I; McArdle HJ; Naska A; Nowicka G; Pentieva K; Sanz Y; Siani A; Sjödin A; Stern M; Tomé D; Van Loveren H; Vinceti M; Willatts P; Lamberg-Allardt C; Przyrembel H; Tetens I; Gudelj Rakic J; Ioannidou S; de Sesmaisons-Lecarré A; Forss AC; Neuhäuser-Berthold M · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusEnergy forThiamin
  9. Effects of thiamine supplementation on exercise-induced fatigue.
    Suzuki M; Itokawa Y · Metabolic brain disease · 1996
    Randomized trial16 participantsEnergy forThiamin
  10. Long-term maintenance treatment with 300 mg thiamine for fatigue in patients with inflammatory bowel disease: results from an open-label extension of the TARIF study.
    Bager P; Hvas CL; Rud CL; Dahlerup JF · Scandinavian journal of gastroenterology · 2022
    Randomized trialEnergy forThiamin
  11. A new perspective on vitamin B12 deficiency in rheumatology: a case-based review.
    Dułak NA; Rytlewska M; Jaskólska M; Chmielewski M · Rheumatology international · 2024
    Case series3 participantsEnergy forVitamin B12
  12. Effects of Vitamin B12 Supplementation on Cognitive Function, Depressive Symptoms, and Fatigue: A Systematic Review, Meta-Analysis, and Meta-Regression.
    Markun S; Gravestock I; Jäger L; Rosemann T; Pichierri G; Burgstaller JM · Nutrients · 2021
    Meta-analysis6,276 participants16 studies pooledEnergy forVitamin B12
  13. Patients' experiences with methylcobalamin injections in amyotrophic lateral sclerosis.
    Zubair AS; Saab L; Scharer K; Khokhar B · Brain circulation · 2024
    Qualitative study5 participantsEnergy forVitamin B12
  14. Cobalamin deficiency: clinical picture and radiological findings.
    Briani C; Dalla Torre C; Citton V; Manara R; Pompanin S; Binotto G; Adami F · Nutrients · 2014
    Narrative reviewEnergy forVitamin B12
  15. Vitamin B12 Deficiency: Common Questions and Answers.
    Patel H; McGuirk R · American family physician · 2025
    Narrative reviewEnergy forVitamin B12
  16. Biotin and contribution to normal energy-yielding metabolism: evaluation of a health claim pursuant to Article 14 of Regulation (EC) No 1924/2006.
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusMetabolism Support forBiotin
  17. Pregnancy and lactation alter biomarkers of biotin metabolism in women consuming a controlled diet.
    Perry CA; West AA; Gayle A; Lucas LK; Yan J; Jiang X; Malysheva O; Caudill MA · The Journal of nutrition · 2015
    Clinical trial75 participantsMetabolism Support forBiotin
  18. Survey of the effect of biotin on glycemic control and plasma lipid concentrations in type 1 diabetic patients in kermanshah in iran (2008-2009)
    Hemmati M, Babaei H, Abdolsalehei M · Oman Medical Journal · 2013
    Randomized trial70 participantsMetabolism Support forBiotin
  19. Chromium picolinate and biotin combination improves glucose metabolism in treated, uncontrolled overweight to obese patients with type 2 diabetes
    César A Albarracin, Bobby C Fuqua, James L Evans, Ira D Goldfine · Diabetes/Metabolism Research and Reviews · 2008
    Randomized trial348 participantsMetabolism Support forBiotin
  20. Biotin supplementation reduces plasma triacylglycerol and VLDL in type 2 diabetic patients and in nondiabetic subjects with hypertriglyceridemia
    Cristina Revilla-Monsalve, Iván Zendejas-Ruiz, Sergio Islas-Andrade, Armida Báez-Saldaña, Miguel Angel Palomino-Garibay, Pedro Martín Hernández-Quiróz, Cristina Fernandez-Mejia · Biomedicine & Pharmacotherapy · 2006
    Randomized trial33 participantsMetabolism Support forBiotin