Proactive 65+ for Men & Women

Proactive 65+ for Men & Women

Bayer One A Day4.7 (2,443 ratings)
Format:Tablet Quantity: 150 Tablet(s) · 75 servings
Goals
$11.46 $0.15 per serving

Product analysis

51 out of 100

Proactive 65+ for Men & Women combines vitamins and minerals with favorable value for several minerals. Most nutrient forms are not specified, making exact comparisons with other multivitamins harder.

AI assessment of the formula, label and price. How scoring works

Nutrient Quality23

Most nutrient forms are unspecified, leaving how well the body can use them uncertain. The few named vitamin forms do not establish a clear quality advantage for the complete mixture.

Ingredient Transparency65

Most nutrient amounts are listed, but the vitamin K amount is missing. Most nutrient forms are also unspecified, limiting exact ingredient comparisons.

Value For Money50

Several minerals offer favorable value, while selenium is relatively costly for its amount. Value for most other nutrients remains uncertain, and several mineral comparisons are older.

Customer Satisfaction86

Customer feedback is very positive. The number of reviews gives more context to satisfaction but does not establish effectiveness or safety.

Product Focus53

The nutrient mix has support across several intended goals, though benefits are uncertain. None of the ingredients is confirmed to be unnecessary.

Format
Tablet
Container
150 Tablet(s)
Per serving
$0.15
Customer rating
4.7 · 2,443 ratings
Report analysis

Goals

Everyday Health
Impact
Highest effect
B+ Ingredient FitA+ PathwaysA- EvidenceA+ Formulation Logic
Folate · 665 mcg DFEVitamin B12 · 50 mcgVitamin D · 30 mcgMagnesium · 100 mgVitamin K · mcgSelenium · 55 mcgZinc · 15 mgVitamin C · 90 mg

Folate and the B vitamins provide nutrients relevant to normal metabolism and blood formation. Vitamin D adds a nutritional contribution relevant to bone and mineral health. Zinc and Selenium add further nutritional contributions. These contributions matter when dietary intake is inadequate; additional benefits above adequate intake are not established.

How this product is rated for Everyday Health

Ingredient fit81

The included ingredients are focused on the supplied nutritional or general-health roles. Declared amounts provide partial coverage of the saved comparisons; this concerns nutrient availability rather than a proven clinical response.
Goal fit
The included ingredients are focused on the supplied nutritional or general-health roles.
Dose adequacy
Declared amounts provide partial coverage of the saved comparisons; this concerns nutrient availability rather than a proven clinical response.

Pathways100

The strongest connection is energy metabolism cofactors. This describes the main supplied functional connection. The findings span several functional areas, indicating broader coverage without establishing added benefit from combining ingredients.
Depth
The strongest connection is energy metabolism cofactors. This describes the main supplied functional connection.
Breadth
The findings span several functional areas, indicating broader coverage without establishing added benefit from combining ingredients.

Evidence86

The saved findings recognize evidence and preparation matches for the included ingredients. Nutritional availability and narrower outcomes do not establish routine broad health improvement.
Evidence strength
Magnesium leads the saved evidence comparison; its nutritional or indication-specific evidence does not establish broad benefits above adequate status.
Studied preparation
Included preparations matched the saved comparison, without establishing superiority of delivery or chemical form.

Formulation logic100

Included ingredients had no missing required partners or configured conflicts and reached the saved minimum amount threshold.
Partner coverage
No required partner was missing among the included ingredients; this does not establish synergy.
Conflicts
No configured ingredient conflict was identified in the supplied facts.
Effective doses
All included ingredients reached the saved minimum amount threshold; excluded low amounts are not necessarily nutritionally worthless.
Study evidence
Folate Supportive 80 studies
Magnesium Supportive 114 studies
Selenium Supportive 70 studies
Vitamin C Supportive 56 studies
Vitamin D Supportive 115 studies
Vitamin K Supportive 34 studies
Zinc Supportive 60 studies
Bone Health
Impact
Highest effect
C+ Ingredient FitA+ PathwaysA+ EvidenceA+ Formulation Logic
Vitamin K · mcgMagnesium · 100 mgCalcium · 500 mgVitamin D · 30 mcgCopper · 1 mgManganese · 2 mgZinc · 15 mgVitamin C · 90 mg

Calcium and magnesium contribute to bone mineral nutrition, while vitamin D supports calcium absorption when intake or status is low. Copper helps cross-link bone collagen in deficiency, and zinc and manganese have supporting roles without established extra skeletal benefit in adequately nourished adults. The 500 mg calcium serving is a practical intake-gap contribution. The saved findings assign no contribution to the zero vitamin K amount or the vitamin C amount.

How this product is rated for Bone Health

Ingredient fit66

The formula’s bone-related ingredients and serving amounts determine its nutritional focus and limitations.
Goal fit
Bone-related nutrients sit within a broader formula containing ingredients without an assessed bone contribution.
Dose adequacy
The serving amounts provide uneven or partial contributions; lower or unresolved amounts limit the saved findings.

Pathways100

The ingredients address bone mineral supply, calcium absorption and regulation, collagen matrix formation, with uneven support across other bone functions.
Depth
The strongest contribution concerns collagen matrix formation.
Breadth
The supported areas are bone mineral supply, calcium absorption and regulation, collagen matrix formation.

Evidence100

The saved preparation and amount findings need to be read alongside the ingredient-specific limits on demonstrated bone outcomes.
Evidence strength
Calcium primarily supports nutritional adequacy; routine fracture prevention is not established.
Studied preparation
The declared preparations match those retained in the saved findings; matching a preparation does not guarantee the same clinical outcome.

Formulation logic100

Partner support and the retained serving amounts determine the formulation finding; no configured conflict was identified.
Partner coverage
The relevant nutrients either stand alone in the saved findings or have their specified partners present.
Conflicts
No configured ingredient conflict was identified in the supplied findings.
Effective doses
The retained ingredients meet the amount threshold used in the saved findings; this is not a proven clinical-effect threshold.
Study evidence
Calcium Supportive 144 studies
Copper Disputed 20 studies
Folate Supportive 50 studies
Magnesium Supportive 48 studies
Manganese Adverse 12 studies
Vitamin A Adverse 56 studies
Vitamin C Supportive 46 studies
Vitamin D Supportive 202 studies
Vitamin K Supportive 78 studies
Zinc Supportive 33 studies
Immunity
Impact
High effect
C- Ingredient FitB+ PathwaysA+ EvidenceA+ Formulation Logic
Magnesium · 100 mgVitamin C · 90 mgZinc · 15 mgVitamin A · 670 mcgVitamin D · 30 mcgSelenium · 55 mcg

Vitamin A supports normal barriers, while zinc and vitamin D contribute to immune regulation. Folate, vitamins B6 and B12 and copper can help restore immune function impaired by low intake. Selenium supplies antioxidant nutrition, without reliable extra benefit when status is adequate. The smaller vitamin C amount was not counted, and magnesium's saved contribution does not establish a routine clinical immune benefit.

How this product is rated for Immunity

Ingredient fit59

Zinc, vitamin D, vitamin A, folate, vitamins B6 and B12, copper and selenium provide relevant immune contributions within a broader formula or product purpose. Nutrient amounts vary, with some supplying substantial contributions and others remaining partial.
Goal fit
Zinc, vitamin D, vitamin A, folate, vitamins B6 and B12, copper and selenium provide relevant immune contributions within a broader formula or product purpose.
Dose adequacy
Nutrient amounts vary, with some supplying substantial contributions and others remaining partial.

Pathways80

The supplied coverage centres on barrier defence and immune-cell regulation.
Depth
The strongest contribution is in immune-cell regulation.
Breadth
The supplied coverage centres on barrier defence and immune-cell regulation.

Evidence100

Zinc supplies the strongest supported contribution at the stated amount; its clinical limits remain relevant.
Evidence strength
Zinc supplies the strongest supported contribution at the stated amount, without establishing infection prevention.
Studied preparation
The supplied findings accept the contributing preparations, without establishing superior clinical effects from particular forms.

Formulation logic100

All included contributions meet the saved amount criterion; this does not establish infection prevention.
Partner coverage
The included contributions have no unmet required ingredient partner.
Conflicts
No listed ingredient conflict was identified in the supplied findings.
Effective doses
All included contributions meet the saved amount criterion; this does not establish infection prevention.
Study evidence
Magnesium Supportive 8 studies
Selenium Mixed 37 studies
Vitamin A Supportive 107 studies
Vitamin C Supportive 53 studies
Vitamin D Supportive 85 studies
Zinc Supportive 73 studies
Impact
Moderate effect
C Ingredient FitF PathwaysA EvidenceA+ Formulation Logic
Iodine · 150 mcgVitamin D · 30 mcgVitamin B5 · 10 mgMagnesium · 100 mgRiboflavin · 1.7 mgThiamin · 1.2 mgVitamin B12 · 50 mcg

Riboflavin, niacin, folate, vitamins B6 and B12, vitamin C and magnesium provide nutritional support relevant to tiredness. Their role is to support adequacy; more intake does not necessarily mean more energy when nutritional needs are already met.

How this product is rated for Energy

Ingredient fit64

Energy-related nutrients sit within a broader formula containing ingredients for other purposes. The saved findings show partial coverage of reference amounts, with some smaller or undisclosed contributions.
Goal fit
Energy-related nutrients sit within a broader formula containing ingredients for other purposes.
Dose adequacy
The saved findings show partial coverage of reference amounts, with some smaller or undisclosed contributions.

Pathways0

The saved contribution centers on nutritional support, with no coverage of the separately assessed energy mechanisms. No assessed energy mechanism reaches the saved threshold for meaningful coverage.
Depth
The saved contribution centers on nutritional support, with no coverage of the separately assessed energy mechanisms.
Breadth
No assessed energy mechanism reaches the saved threshold for meaningful coverage.

Evidence94

Vitamin D provides the strongest evidence contribution among ingredients meeting the saved amount criteria; the practical benefit remains dependent on context. Most counted ingredients match accepted preparations, with the remaining mismatch involving Iodine.
Evidence strength
Vitamin D provides the strongest evidence contribution among ingredients meeting the saved amount criteria; the practical benefit remains dependent on context.
Studied preparation
Most counted ingredients match accepted preparations, with the remaining mismatch involving Iodine.

Formulation logic100

The counted ingredients can work independently or have their relevant partner present. No configured ingredient conflict was identified in the saved findings. All ingredients counted in this finding reach its minimum amount threshold.
Partner coverage
The counted ingredients can work independently or have their relevant partner present.
Conflicts
No configured ingredient conflict was identified in the saved findings.
Effective doses
All ingredients counted in this finding reach its minimum amount threshold.
Study evidence
Iodine Adverse 3 studies
Magnesium Supportive 4 studies
Thiamin Disputed 12 studies
Vitamin D Supportive 32 studies
Hair Health
Impact
Moderate effect
C Ingredient FitF PathwaysA+ EvidenceA+ Formulation Logic
Biotin · 30 mcgVitamin D · 30 mcgZinc · 15 mgVitamin C · 90 mg

Zinc may help with diffuse shedding when low zinc is the cause. That benefit depends on a deficiency, rather than applying to every kind of thinning hair. The other vitamins and minerals here have nutritional roles, but their presence doesn't mean you'll get more regrowth when you already get enough zinc.

How this product is rated for Hair Health

Ingredient fit61

Zinc may help with shedding caused by zinc deficiency. Zinc supplies 15 mg per selected serving; that amount alone doesn't predict hair growth.
Goal fit
Several nutrients relate to hair nutrition, alongside ingredients with other roles. Zinc may help with shedding caused by zinc deficiency.
Dose adequacy
Zinc supplies 15 mg per selected serving; that amount alone doesn't predict hair growth.

Pathways18

Antioxidant-related nutrient roles are relevant to hair follicles, but they do not by themselves demonstrate regrowth.
Depth
Antioxidant-related nutrient roles are relevant to hair follicles, but they do not by themselves demonstrate regrowth.
Breadth
The ingredients don't demonstrate broad effects across the different causes of thinning hair.

Evidence97

Zinc may help with shedding caused by zinc deficiency. Preparation-specific hair benefits cannot automatically be transferred to Iodine.
Evidence strength
Zinc may help with shedding caused by zinc deficiency.
Studied preparation
Preparation-specific hair benefits cannot automatically be transferred to Iodine.

Formulation logic97

No particular conflict or missing ingredient partner is identified. This does not imply an added hair benefit from combining ingredients.
Partner coverage
No missing partner is identified for the ingredients relevant to this goal.
Conflicts
No particular ingredient conflict is identified.
Effective doses
Some amounts are unresolved or relatively low; this limits comparison without proving that the serving cannot help.
Study evidence
Biotin Supportive 4 studies
Copper Adverse 4 studies
Folate Mixed 15 studies
Iodine No effect 1 study
Niacin Disputed 2 studies
Selenium Disputed 7 studies
Vitamin A Disputed 13 studies
Vitamin D Disputed 34 studies
Zinc Supportive 22 studies

Ingredients

IngredientAmount per servingScore
Vitamin A (Beta-Carotene)
670 mcg
Vitamin C
90 mg
Vitamin D
30 mcg
Vitamin K
0 mcg
Thiamine
1.2 mg
Riboflavin
1.7 mg
Niacin
20 mg
Vitamin B6
2 mg
Folate
665 mcg DFE
Vitamin B12
50 mcg
Biotin
30 mcg
Pantothenic Acid
10 mg
Calcium
500 mg 59
Iodine
150 mcg 88
Magnesium
100 mg
Zinc
15 mg
Selenium
55 mcg 37
Copper
1 mg 57
Manganese
2 mg 58
Chromium
24 mcg
Dairy Free Seniors 50+
Report overview
Iodine · 150 mcg OverallScore88
C+ Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyA+ Value
150 mcg of iodine per serving comes at a low cost per serving. The amount supports daily iodine intake. The iodine source is unclear; potassium iodide appears in Other Ingredients, but its contribution to the listed iodine is unknown.
How this ingredient is rated

Active Ingredient Quality & Bioavailability69

The iodine source is unclear; potassium iodide appears in Other Ingredients, but its contribution to the listed iodine is unknown. No marine source is indicated, so the seaweed-specific purity concern does not apply.
Iodine Form & Bioavailability
The iodine source is unclear; potassium iodide appears in Other Ingredients, but its contribution to the listed iodine is unknown.
Marine Source Purity & Sourcing
No marine source is indicated, so the seaweed-specific purity concern does not apply.

Dose, Safety & Label Transparency100

150 mcg of iodine per serving supports daily iodine intake. The iodine amount is stated, though the main iodine entry does not identify its source.
Dosage Efficacy for Daily Support
150 mcg of iodine per serving supports daily iodine intake.
Dosage Safety & Upper Limits
The serving amount is below the upper intake level.
Elemental Iodine Transparency
The iodine amount is stated, though the main iodine entry does not identify its source.

Value100

The cost per serving is low.
Price Per Effective Serving
The cost per serving is low.
Calcium · 500 mg OverallScore59
F Active Ingredient Quality & BioavailabilityC Dose, Safety & Label TransparencyA+ Value
500 mg of calcium per serving comes at a low cost per serving. The calcium source remains unclear, and the compounds listed under Other Ingredients cannot be assigned to its total. An artificial additive is listed.
How this ingredient is rated

Active Ingredient Quality & Bioavailability37

The label states 500 mg of calcium per serving. The calcium source is unclear; Other Ingredients lists Calcium Carbonate and Calcium D-Pantothenate, but their contribution to the calcium total is unknown.
Calcium Form & Absorption Potential
The calcium source is unclear; Other Ingredients lists Calcium Carbonate and Calcium D-Pantothenate, but their contribution to the calcium total is unknown.
Elemental Calcium Transparency
The label states 500 mg of calcium per serving.

Dose, Safety & Label Transparency60

Each serving provides 500 mg of calcium. An artificial additive is listed.
Absorption-Optimized Serving Dose
Each serving provides 500 mg of calcium.
Formulation Purity & Additives
An artificial additive is listed.

Value100

The cost per serving is low.
Price Per Serving Efficiency
The cost per serving is low.
Manganese · 2 mg OverallScore58
F Active Ingredient Quality & BioavailabilityA- Dose, Safety & Label TransparencyA+ Value
Each serving provides 2 mg of manganese. The cost per serving is low. Manganese sulfate appears in Other Ingredients, but the source of the stated manganese amount and its proportions are unclear.
How this ingredient is rated

Active Ingredient Quality & Bioavailability8

Manganese sulfate appears in Other Ingredients, but the source of the stated manganese amount and its proportions are unclear.
Manganese Chemical Form
Manganese sulfate appears in Other Ingredients, but the source of the stated manganese amount and its proportions are unclear.

Dose, Safety & Label Transparency86

Each serving provides 2 mg of manganese. The source of that amount is unclear.
Manganese Dosage Efficacy & Safety
Each serving provides 2 mg of manganese.
Elemental Weight Disclosure
The label states 2 mg of manganese, but does not assign a source to that amount.

Value100

The cost per serving is low.
Price per Serving vs. Median
The cost per serving is low.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. What is the impact of daily oral supplementation of vitamin D3 (cholecalciferol) plus calcium on the incidence of hip fracture in older people? A systematic review and meta-analysis.
    Manoj P; Derwin R; George S · International journal of older people nursing · 2023
    Meta-analysis12,620 participants7 studies pooledBone Health forCalcium
  2. Calcium supplementation prevents seasonal bone loss and changes in biochemical markers of bone turnover in elderly New England women: a randomized placebo-controlled trial.
    Storm D; Eslin R; Porter ES; Musgrave K; Vereault D; Patton C; Kessenich C; Mohan S; Chen T; Holick MF; Rosen CJ · The Journal of clinical endocrinology and metabolism · 1998
    Randomized trial60 participantsBone Health forCalcium
  3. The effects of calcium supplementation (milk powder or tablets) and exercise on bone density in postmenopausal women.
    Prince R; Devine A; Dick I; Criddle A; Kerr D; Kent N; Price R; Randell A · Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 1995
    Randomized trial168 participantsBone Health forCalcium
  4. The efficacy of calcium supplementation alone in elderly Thai women over a 2-year period: a randomized controlled trial.
    Rajatanavin R; Chailurkit L; Saetung S; Thakkinstian A; Nimitphong H · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2014
    Randomized trial404 participantsBone Health forCalcium
  5. Calcium-enriched foods and bone mass growth in prepubertal girls: a randomized, double-blind, placebo-controlled trial.
    Bonjour JP; Carrie AL; Ferrari S; Clavien H; Slosman D; Theintz G; Rizzoli R · The Journal of clinical investigation · 1997
    Randomized trial149 participantsBone Health forCalcium
  6. The Association between Dietary and Circulating Copper Levels and Osteoporosis: a Scoping Review.
    Ju Y; Xiong W; Pang Y; Chen Z; Hou J; Zheng S; Li Z; Liu T; Xia H; Xia M; Zhong Y; Li J; Jiang X · Biological trace element research · 2026
    Scoping review18 studies pooledBone Health forCopper
  7. Association between dietary copper, iron, zinc, selenium intake and osteopenia or osteoporosis in elderly hypertensive patients: a retrospective cohort study.
    Chen M; Jia L; Gao R · Frontiers in nutrition · 2024
    Cohort study5,286 participantsBone Health forCopper
  8. Associations of dietary copper intake with total bone mineral density and lumbar spine bone mineral density in American adults.
    Hu M; Wang Z; Li C; Zheng Y; Hu J · Medicine · 2025
    Cross-sectional studyBone Health forCopper
  9. The association between dietary mineral intake and bone mineral density: a cross-sectional study.
    Wei M; Wei J; Huang S · Journal of health, population, and nutrition · 2025
    Cross-sectional study11,520 participantsBone Health forCopper
  10. Association between dietary copper intake and bone mineral density in children and adolescents aged 8-19 years: A cross-sectional study.
    Cui A; Yan J; Li H; Fan Z; Wei X; Wang H; Zhuang Y · PloS one · 2024
    Cross-sectional study6,965 participantsBone Health forCopper
  11. Association between RBC folate and lumbar bone mineral density in postmenopausal women, a cross-sectional study from NHANES 2009-2018.
    Wei H; Jin Z; Zhou L; Tang G; Chai S; Che X; Tan Y; Zeng W · Frontiers in endocrinology · 2025
    Cross-sectional study1,315 participantsBone Health forFolate
  12. Genetic variants modify the associations of concentrations of methylmalonic acid, vitamin B-12, vitamin B-6, and folate with bone mineral density.
    Liu CT; Karasik D; Xu H; Zhou Y; Broe K; Cupples LA; Cpgm de Groot L; Ham A; Hannan MT; Hsu YH; Jacques P; McLean RR; Paul L; Selhub J; Trajanoska K; van der Velde N; van Schoor N; Kiel DP · The American journal of clinical nutrition · 2021
    Cohort study4,310 participantsBone Health forFolate
  13. Adequate Intake and Supplementation of B Vitamins, in Particular Folic Acid, can Play a Protective Role in Bone Health.
    Rondanelli M; Tartara A; Fossari F; Vecchio V; Faliva MA; Naso M; Perna S; Nichetti M; Peroni G · Current aging science · 2022
    Narrative review35,298 participants29 studies pooledBone Health forFolate Bone Health forVitamin B6
  14. Relation of homocysteine, folate, and vitamin B12 to bone mineral density of postmenopausal women.
    Cagnacci A; Baldassari F; Rivolta G; Arangino S; Volpe A · Bone · 2004
    Cross-sectional study161 participantsBone Health forFolate
  15. Dietary intake of folate, but not vitamin B2 or B12, is associated with increased bone mineral density 5 years after the menopause: results from a 10-year follow-up study in early postmenopausal women.
    Rejnmark L; Vestergaard P; Hermann AP; Brot C; Eiken P; Mosekilde L · Calcified tissue international · 2008
    Cohort study1,869 participantsBone Health forFolate
  16. Association between Serum Magnesium and Fractures: A Systematic Review and Meta-Analysis of Observational Studies.
    Dominguez LJ; Veronese N; Ciriminna S; Pérez-Albela JL; Vásquez-López VF; Rodas-Regalado S; Di Bella G; Parisi A; Tagliaferri F; Barbagallo M · Nutrients · 2023
    Meta-analysis119,755 participants4 studies pooledBone Health forMagnesium
  17. Bioabsorbable Magnesium-Based Materials Potential and Safety in Bone Surgery: A Systematic Review.
    Hung CH; Kwok YC; Yip J; Wong HH; Leung YY · Craniomaxillofacial trauma & reconstruction · 2025
    Systematic review386 participants8 studies pooledBone Health forMagnesium
  18. Vascularized bone grafting fixed by biodegradable magnesium screw for treating osteonecrosis of the femoral head.
    Zhao D; Huang S; Lu F; Wang B; Yang L; Qin L; Yang K; Li Y; Li W; Wang W; Tian S; Zhang X; Gao W; Wang Z; Zhang Y; Xie X; Wang J; Li J · Biomaterials · 2016
    Randomized trial48 participantsBone Health forMagnesium
  19. An update on magnesium and bone health.
    Rondanelli M; Faliva MA; Tartara A; Gasparri C; Perna S; Infantino V; Riva A; Petrangolini G; Peroni G · Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2022
    Narrative reviewBone Health forMagnesium
  20. Sex-specific differences in the association of magnesium intake with femoral neck bone mineral density among older adults.
    Wang B; Tan X; Yao X; Zhu Z · Endocrine connections · 2025
    Cross-sectional study1,343 participantsBone Health forMagnesium