St. John's Positive Thoughts

St. John's Positive Thoughts

Source Naturals4.6 (646 ratings)
Format:Tablet Quantity: 45 Tablet(s) · 15 servings
Goals
$7.38 $0.49 per serving

Product analysis

45 out of 100

St. John's Positive Thoughts combines mood-related ingredients with nutrients that can help fill dietary gaps. Unclear herbal preparations and small amounts of some calming ingredients limit how confidently the wider blend can be expected to help.

AI assessment of the formula, label and price. How scoring works

Nutrient Quality40

Several vitamin forms are clearly identified, giving part of the formula a more understandable quality picture. The magnesium mixture and several herbal preparations are less clear, limiting comparison of absorption and preparation quality.

Ingredient Transparency66

Amounts are listed and many nutrient forms are named. Numerous other forms and the breakdown of the botanical and magnesium mixtures remain unclear.

Value For Money37

Value is uneven, with favorable vitamin B6 value but costly contributions from several amino acids and other additions. The partly unresolved magnesium mixture also provides little value for its form quality.

Customer Satisfaction75

Customer feedback is broadly positive across hundreds of ratings. The review count offers a useful picture of satisfaction without proving health benefits.

Product Focus8

The mixture spans mood, stress and nutrition, making its purpose broad. Valerian's sedating effect can work against daytime alertness, while several calming ingredients are below the amounts behind their more specific findings.

Format
Tablet
Container
45 Tablet(s)
Per serving
$0.49
Customer rating
4.6 · 646 ratings
Report analysis

Goals

Mood Support
Impact
Highest effect
B- Ingredient FitB+ PathwaysA+ EvidenceA+ Formulation Logic
Folate · 1360 mcg DFEVitamin B6 · 50 mgVitamin B12 · 50 mcgMagnesium · 200 mg
Study evidence
Folate Supportive 84 studies
GABA Supportive 12 studies
Magnesium Supportive 60 studies
Theanine Supportive 12 studies
Valerian Supportive 17 studies
Vitamin B6 Supportive 19 studies
Zinc Supportive 43 studies
Stress Relief
Impact
High effect
C+ Ingredient FitB+ PathwaysA- EvidenceA+ Formulation Logic
Magnesium · 200 mgFolate · 1360 mcg DFEVitamin B12 · 50 mcgGABA · 500 mgVitamin B6 · 50 mgVitamin C · 51 mgTheanine · 50 mg
Study evidence
Folate Supportive 19 studies
GABA Supportive 6 studies
Magnesium Supportive 13 studies
Taurine Supportive 5 studies
Theanine Supportive 16 studies
Valerian Supportive 18 studies
Vitamin C Supportive 11 studies
Zinc Supportive 9 studies
Sleep Support
Impact
High effect
D Ingredient FitB+ PathwaysA+ EvidenceA+ Formulation Logic
Magnesium · 200 mgTheanine · 50 mg
Study evidence
GABA Supportive 4 studies
Magnesium Supportive 23 studies
Taurine Not classified

No linked studies yet.

Theanine Supportive 8 studies
Valerian Supportive 31 studies
Zinc Supportive 14 studies
Impact
Moderate effect
C Ingredient FitF PathwaysA- EvidenceA Formulation Logic
Vitamin B5 · 25 mgMagnesium · 200 mgRiboflavin · 25 mgThiamin · 25 mgVitamin B12 · 50 mcg
Study evidence
Magnesium Supportive 4 studies
Theanine Not classified

No linked studies yet.

Thiamin Disputed 12 studies
Testosterone Support
Impact
Moderate effect
F Ingredient FitD+ PathwaysA EvidenceA+ Formulation Logic
Magnesium · 200 mgZinc · 10 mg
Study evidence
Magnesium Disputed 5 studies
Taurine Not classified

No linked studies yet.

Zinc Disputed 7 studies
Impact
High effect
C+ Ingredient FitB+ PathwaysA- EvidenceA+ Formulation Logic
Folate · 1360 mcg DFEVitamin B12 · 50 mcgMagnesium · 200 mgTaurine · 185 mgZinc · 10 mgVitamin C · 51 mg
Study evidence
Folate Supportive 80 studies
Magnesium Supportive 114 studies
Taurine No effect 3 studies
Vitamin C Supportive 56 studies
Zinc Supportive 60 studies

Ingredients

IngredientAmount per servingScore
Calories
10 Calorie(s)
Total Carbohydrates
1 Gram(s)
Vitamin C (Zinc Ascorbate)
51 mg
Thiamine (Thiamine Mononitrate)
25 mg 65
Riboflavin
25 mg 57
Niacin (Niacinamide)
50 mg 65
Vitamin B6 (Pyridoxine Hydrochloride)
50 mg 73
Folate (Folic Acid)
1360 mcg DFE
Vitamin B12 (Cyanocobalamin)
50 mcg
Biotin
300 mcg 59
Pantothenic Acid (Calcium D-Pantothenate)
25 mg 61
Calcium (Dibasic Calcium Phosphate)
124 mg
Magnesium (Magnesium Oxide, Taurine Complex)
200 mg 42
Zinc (Zinc Ascorbate)
10 mg
Manganese (Manganese Citrate)
3 mg 76
Sodium
15 mg
St. John's Wort aerial parts extract
900 mg 100
GABA
500 mg 73
L-Tyrosine
200 mg 41
Taurine (Magnesium Taurine Complex)
185 mg 45
Holy Basil leaf extract
100 mg
Lemon Balm
100 mg
Valerian root extract
100 mg 70
L-Phenylalanine
100 mg 65
DMAE (DMAE Bitartrate)
60 mg 82
L-Theanine
50 mg 70
N-Acetyl L-Tyrosine
50 mg
Relora (Magnolia bark extract, Phellodendron bark extract)
50 mg
Adults 18–50
Report overview
B+ Active Ingredient Quality & BioavailabilityA- Dose, Safety & Label TransparencyD+ Value
Each serving provides 3 mg of manganese, an amount suited to nutritional maintenance, at a moderately high cost per serving. The manganese comes from Manganese Citrate.
How this ingredient is rated

Active Ingredient Quality & Bioavailability80

The manganese comes from Manganese Citrate.
Manganese Chemical Form
The manganese comes from Manganese Citrate.

Dose, Safety & Label Transparency86

A serving provides 3 mg of manganese. The manganese amount and source are stated.
Manganese Dosage Efficacy & Safety
A serving provides 3 mg of manganese, an amount suited to nutritional maintenance.
Elemental Weight Disclosure
The manganese amount and source are stated.

Value50

The cost per serving is moderately high.
Price per Serving vs. Median
The cost per serving is moderately high.
A+ Ingredient Form & Label QualityF Dose, Safety & Label TransparencyA Value
50 mg of B6 per serving exceeds the European adult upper limit of 12 mg per day; total daily intake may be higher. The cost per amount of B6 is relatively low. The B6 source is Pyridoxine Hydrochloride.
How this ingredient is rated

Ingredient Form & Label Quality100

The B6 source is Pyridoxine Hydrochloride. No artificial colors, titanium dioxide or talc are indicated.
Vitamin B6 Form Identification
The B6 source is Pyridoxine Hydrochloride.
Clean Label and Excipient Purity
No artificial colors, titanium dioxide or talc are indicated.

Dose, Safety & Label Transparency37

50 mg of B6 per serving exceeds the European adult upper limit of 12 mg per day; total daily intake may be higher. The source is also stated.
Vitamin B6 Dose & Safety Policy
50 mg of B6 per serving exceeds the European adult upper limit of 12 mg per day; total daily intake may be higher.
Label Transparency
The label states both the B6 amount and its source.

Value91

The cost per amount of B6 is relatively low.
Vitamin B6 Price Efficiency
The cost per amount of B6 is relatively low.
GABA · 500 mg OverallScore73
B- Active Ingredient Quality & BioavailabilityA Dose, Safety & Label TransparencyD- Value
The serving declares 500 mg of GABA. The cost per serving is high. GABA is named without a specific source or production method. The Other Ingredients panel lists at least one flow aid.
How this ingredient is rated

Active Ingredient Quality & Bioavailability70

GABA is named without a specific source or production method.
GABA Source & Production Method
GABA is named without a specific source or production method.

Dose, Safety & Label Transparency93

The serving declares 500 mg of GABA. The Other Ingredients panel lists at least one flow aid.
GABA Dosage Adequacy & Transparency
The serving declares 500 mg of GABA.
Label Purity & Excipient Quality
The Other Ingredients panel lists at least one flow aid.

Value40

The cost per serving is high.
Price per Effective Dose
The cost per serving is high.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Magnesium-L-threonate improves sleep quality and daytime functioning in adults with self-reported sleep problems: A randomized controlled trial.
    Hausenblas HA; Lynch T; Hooper S; Shrestha A; Rosendale D; Gu J · Sleep medicine: X · 2025
    Randomized trial80 participantsEnergy forMagnesium
  2. Total magnesium intake and risk of frailty in older women.
    Struijk EA; Fung TT; Bischoff-Ferrari HA; Willett WC; Lopez-Garcia E · Journal of cachexia, sarcopenia and muscle · 2024
    Cohort study81,524 participantsEnergy forMagnesium
  3. Red blood cell magnesium and chronic fatigue syndrome.
    Cox IM; Campbell MJ; Dowson D · Lancet (London, England) · 1991
    Randomized trial32 participantsEnergy forMagnesium
  4. Exercise, magnesium and immune function.
    Laires MJ; Monteiro C · Magnesium research · 2008
    Narrative reviewEnergy forMagnesium
  5. Physicochemical properties of and volatile compounds in riboflavin fortified cloudy apple juice; study of its effect on job fatigue among Egyptian construction workers.
    Fouad S; Ibrahim GE; Hussein AMS; Ibrahim FA; El Gendy A · Heliyon · 2021
    Non-randomized trialEnergy forRiboflavin
  6. Vitamin B status in patients with chronic fatigue syndrome.
    Heap LC; Peters TJ; Wessely S · Journal of the Royal Society of Medicine · 1999
    Case-control study30 participantsEnergy forRiboflavin
  7. B-vitamins, related vitamers, and metabolites in patients with quiescent inflammatory bowel disease and chronic fatigue treated with high dose oral thiamine.
    Bager P; Hvas CL; Hansen MM; Ueland P; Dahlerup JF · Molecular medicine (Cambridge, Mass.) · 2023
    Observational studyEnergy forRiboflavin
  8. Metabolic features of chronic fatigue syndrome.
    Naviaux RK; Naviaux JC; Li K; Bright AT; Alaynick WA; Wang L; Baxter A; Nathan N; Anderson W; Gordon E · Proceedings of the National Academy of Sciences of the United States of America · 2024
    Case-control study84 participantsEnergy forRiboflavin
  9. Effectiveness of Riboflavin in Inherited Metabolic Diseases: A Systematic Review
    Bregje Jaeger, Nina N Stolwijk, Femke Aaldering, Charlotte A Ruys, Marije Smits, Nicole I Wolf, Carla E M Hollak, Annet M Bosch · Journal of Inherited Metabolic Disease · 2026
    Systematic review381 studies pooledEnergy forRiboflavin
  10. Influence of thiamin supplementation on the health and general well-being of an elderly Irish population with marginal thiamin deficiency.
    Smidt LJ; Cremin FM; Grivetti LE; Clifford AJ · Journal of gerontology · 1991
    Randomized trial80 participantsEnergy forThiamin
  11. Randomised clinical trial: high-dose oral thiamine versus placebo for chronic fatigue in patients with quiescent inflammatory bowel disease.
    Bager P; Hvas CL; Rud CL; Dahlerup JF · Alimentary pharmacology & therapeutics · 2021
    Randomized trial40 participantsEnergy forThiamin
  12. Dietary reference values for thiamin.
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA); Turck D; Bresson JL; Burlingame B; Dean T; Fairweather-Tait S; Heinonen M; Hirsch-Ernst KI; Mangelsdorf I; McArdle HJ; Naska A; Nowicka G; Pentieva K; Sanz Y; Siani A; Sjödin A; Stern M; Tomé D; Van Loveren H; Vinceti M; Willatts P; Lamberg-Allardt C; Przyrembel H; Tetens I; Gudelj Rakic J; Ioannidou S; de Sesmaisons-Lecarré A; Forss AC; Neuhäuser-Berthold M · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusEnergy forThiamin
  13. Effects of thiamine supplementation on exercise-induced fatigue.
    Suzuki M; Itokawa Y · Metabolic brain disease · 1996
    Randomized trial16 participantsEnergy forThiamin
  14. Long-term maintenance treatment with 300 mg thiamine for fatigue in patients with inflammatory bowel disease: results from an open-label extension of the TARIF study.
    Bager P; Hvas CL; Rud CL; Dahlerup JF · Scandinavian journal of gastroenterology · 2022
    Randomized trialEnergy forThiamin
  15. A new perspective on vitamin B12 deficiency in rheumatology: a case-based review.
    Dułak NA; Rytlewska M; Jaskólska M; Chmielewski M · Rheumatology international · 2024
    Case series3 participantsEnergy forVitamin B12
  16. Effects of Vitamin B12 Supplementation on Cognitive Function, Depressive Symptoms, and Fatigue: A Systematic Review, Meta-Analysis, and Meta-Regression.
    Markun S; Gravestock I; Jäger L; Rosemann T; Pichierri G; Burgstaller JM · Nutrients · 2021
    Meta-analysis6,276 participants16 studies pooledEnergy forVitamin B12
  17. Patients' experiences with methylcobalamin injections in amyotrophic lateral sclerosis.
    Zubair AS; Saab L; Scharer K; Khokhar B · Brain circulation · 2024
    Qualitative study5 participantsEnergy forVitamin B12
  18. Cobalamin deficiency: clinical picture and radiological findings.
    Briani C; Dalla Torre C; Citton V; Manara R; Pompanin S; Binotto G; Adami F · Nutrients · 2014
    Narrative reviewEnergy forVitamin B12
  19. Vitamin B12 Deficiency: Common Questions and Answers.
    Patel H; McGuirk R · American family physician · 2025
    Narrative reviewEnergy forVitamin B12
  20. Intakes of Folate, Vitamin B6, and Vitamin B12 in Relation to All-Cause and Cause-Specific Mortality: A National Population-Based Cohort.
    Bo Y; Xu H; Zhang H; Zhang J; Wan Z; Zhao X; Yu Z · Nutrients · 2022
    Cohort study55,569 participantsEveryday Health forFolate